BGC0002194 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002194 (Epicoccum nigrum)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	15,466	epipyrone A	PKS	100%

BGC0002194 - Region 1 - T1PKS

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Location: 1 - 15,466 nt. (total: 15,466 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 15,467
Label		BGC0002194

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002194	1.00	Polyketide	epipyrone A	Epicoccum nigrum
BGC0002525	0.34	Polyketide	fusarubin, 1233A, 1233B, NG-391, lucilactaene	Fusarium sp.
BGC0002191	0.33	Polyketide	prolipyrone B, gibepyrone D	Fusarium graminearum PH-1
BGC0001252	0.33	Polyketide	UNII-YC2Q1O94PT	Alternaria alternata
BGC0002610	0.33	Terpene	stellatic acid	Aspergillus stellatus
BGC0001606	0.32	Polyketide	gibepyrone-A	Fusarium fujikuroi IMI 58289
BGC0002224	0.32	Polyketide	zopfiellin	Diffractella curvata
BGC0002222	0.32	Polyketide	zopfiellin	Diffractella curvata
BGC0002155	0.31	Polyketide	nectriapyrone C, nectriapyrone D, nectriapyrone	Pyricularia oryzae 70-15
BGC0002515	0.30	Polyketide	solanapyrone A	Ascochyta rabiei

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002194	1.00	Polyketide	epipyrone A	Epicoccum nigrum
BGC0002525	0.67	Polyketide	fusarubin, 1233A, 1233B, NG-391, lucilactaene	Fusarium sp.
BGC0002191	0.66	Polyketide	prolipyrone B, gibepyrone D	Fusarium graminearum PH-1
BGC0001252	0.66	Polyketide	UNII-YC2Q1O94PT	Alternaria alternata
BGC0002610	0.66	Terpene	stellatic acid	Aspergillus stellatus
BGC0001606	0.66	Polyketide	gibepyrone-A	Fusarium fujikuroi IMI 58289
BGC0002224	0.66	Polyketide	zopfiellin	Diffractella curvata
BGC0002222	0.65	Polyketide	zopfiellin	Diffractella curvata
BGC0002155	0.64	Polyketide	nectriapyrone C, nectriapyrone D, nectriapyrone	Pyricularia oryzae 70-15
BGC0002515	0.63	Polyketide	solanapyrone A	Ascochyta rabiei

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 15466:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Me-redmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

B5807_07929

PKS_AT (587..893): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 83.3%; Methylmalonyl-CoA: 70.8%; 2-Methylbutyryl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 86.1
Methylmalonyl-CoA: 84.5
Methoxymalonyl-CoA: 82.8
Isobutyryl-CoA: 75.4
Ethylmalonyl-CoA: 47.0
Propionyl-CoA: 37.0
2-Methylbutyryl-CoA: 34.7
trans-1,2-CPDA: 27.0
inactive: 23.3
fatty_acid: 21.2
Acetyl-CoA: 20.7
Benzoyl-CoA: 18.3
3-Methylbutyryl-CoA: 16.1
CHC-CoA: 13.8