BGC0002197: terrestric acid biosynthetic gene cluster from Penicillium crustosum
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Location: 1 - 33,648 nt. (total: 33,648 nt).
This entry is originally from NCBI GenBank MK360919.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002197
Short description terrestric acid biosynthetic gene cluster from Penicillium crustosum
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
  • NRPS (Type I)
Loci
MK360919.1
1 - 33648
via Heterologous expression, Enzymatic assays
Compounds
  • terrestric acid
Species Penicillium crustosum [taxonomy]
References
Chemical products information
terrestric acid Evidence:
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Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • QBK15049.1
 1639 - 13691 (-) PKS-NRPS hybrid TraA
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    • QBK15050.1
    		 14815 - 16814 (+) cytochrome P450 TraB
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      • QBK15051.1
      		 17342 - 18663 (-) hypothetical protein TraC
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        • QBK15052.1
        		 19823 - 20764 (-) NAD(P)H dehydrogenase TraD
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          • QBK15053.1
          		 21458 - 21928 (+) hypothetical protein TraE
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            • QBK15054.1
            		 22417 - 24211 (-) major facilitator TraF
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              • QBK15055.1
              		 25000 - 26171 (+) enoyl reductase TraG
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                • QBK15056.1
                		 27346 - 28433 (+) FeII/2-oxoglutarate-dependent oxygenase TraH
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                  Biosynthesis information

                  Biosynthetic modules

                  Name
                  Unk01
                  Type
                  nrps-type1
                  Genes
                  QBK15049.1
                  Substrates
                  malic acid (evidence: Structure-based inference, Feeding study)
                  Integrated Monomers
                  Domains
                  adenylation
                  Annotation changelog

                  Entry version: 1

                  Date
                  Changes
                  Submitters
                  Reviewers
                  2022-09-15
                  Entry added
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  2022-09-15
                  Added NRP substrate specificities
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  Detailed domain annotation
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