BGC0002198 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002198 (Aspergillus terreus var. terreus)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS	1	114,922	nanangelenin B/terreazepine	NRPS:Type I	100%

BGC0002198 - Region 1 - NRPS

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Location: 1 - 114,922 nt. (total: 114,922 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 114,923
Label		BGC0002198

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002198	0.61	NRP	nanangelenin B, terreazepine	Aspergillus terreus var. terreus
BGC0002157	0.33	NRP, Alkaloid	(-)-ditryptophenaline	Aspergillus flavus
BGC0000900	0.32	Other	ferrichrome	Aspergillus oryzae
BGC0001249	0.31	NRP	dimethylcoprogen	Alternaria alternata
BGC0002710	0.30	NRP	metachelin C, metachelin A, metachelin A-CE, metachelin B, dimerumic acid 11-mannoside, dimerumic acid	Metarhizium robertsii ARSEF 23
BGC0002208	0.30	NRP	oxepinamide F	Aspergillus ustus
BGC0002242	0.30	NRP	oxepinamide D	Aspergillus ustus
BGC0001261	0.28	NRP	AM-toxin	Alternaria alternata
BGC0000348	0.27	NRP	ergovaline	Epichloe festucae var. lolii
BGC0000420	0.26	NRP	histidyltryptophanyldiketopiperazine, dehydrohistidyltryptophanyldiketopiperazine, roquefortine D, roquefortine C, glandicoline A, glandicoline B, meleagrine	Penicillium rubens Wisconsin 54-1255

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002198	1.00	NRP	nanangelenin B, terreazepine	Aspergillus terreus var. terreus
BGC0002157	0.66	NRP, Alkaloid	(-)-ditryptophenaline	Aspergillus flavus
BGC0000900	0.66	Other	ferrichrome	Aspergillus oryzae
BGC0002245	0.65	Terpene	terpestacin, preterpestacin 3, preterpestacin 2, preterpestacin 1	Bipolaris maydis C5
BGC0002219	0.65	Terpene	(-)-(R)-nephthenol	Stereum hirsutum FP-91666 SS1
BGC0001249	0.65	NRP	dimethylcoprogen	Alternaria alternata
BGC0002710	0.64	NRP	metachelin C, metachelin A, metachelin A-CE, metachelin B, dimerumic acid 11-mannoside, dimerumic acid	Metarhizium robertsii ARSEF 23
BGC0002208	0.64	NRP	oxepinamide F	Aspergillus ustus
BGC0000348	0.63	NRP	ergovaline	Epichloe festucae var. lolii
BGC0001820	0.62	NRP	verticillin	Gliocladium sp.

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 72114 - 114922:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

FAC38_35

AMP-binding (245..648): X

nrpys: Ant

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: GIILFGVGVK
Nearest Stachelhaus code(s):: Ant GIILFGVGVK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1351..1753): X

nrpys: Kyn

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAAMIMGIAK
Nearest Stachelhaus code(s):: Kyn DAAMIMGIAK (100% 8Å match)
Stachelhaus code match:: 100% (strong)