LOCUS       BGC0002207             22513 bp    DNA     linear   PLN 08-MAY-2018
DEFINITION  Psilocybe cyanescens strain 2631 scaffold5617, whole genome shotgun
            sequence.
ACCESSION   BGC0002207
VERSION     BGC0002207
KEYWORDS    .
SOURCE      Psilocybe cyanescens
  ORGANISM  Psilocybe cyanescens
            Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina;
            Agaricomycetes; Agaricomycetidae; Agaricales; Agaricineae;
            Strophariaceae; Psilocybe.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 17:08:21
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     subregion       1..22513
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0002207"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..22513
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(508..1666)
                     /locus_tag="CVT25_004288"
     mRNA            complement(join(508..1368,1439..1666))
                     /locus_tag="CVT25_004288"
                     /product="Psilocin Phosphotransferase (PsiK)"
     CDS             complement(join(508..1368,1439..1666))
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="CVT25_004288"
                     /product="Psilocin Phosphotransferase (PsiK)"
                     /protein_id="PPQ83229.1"
                     /sec_met_domain="APH (E-value: 2.9e-11, bitscore: 32.8,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAFDLKTPEGLLLYLTRHLSLDVDPSGVKRLSGGFVNVTWRIRLN
                     APYQGHTSIILKHAQPHLSSDEDFKIGVERSAYEYQALKVMSANQEVLGGDDSRVSVPE
                     GLHYDVENNALIMQDVGTMKTLLDYATAKPPLSTEIASLVGTEIGAFIARLHNLGRKRR
                     DQPAFKFFSGNIVGRTTADQLYQTIIPNAAKYGINDPLLPTVVKDLVGEVMNSEETLIM
                     ADLWSGNILLEFVEGNPSELKKIWLVDWELCKYGPASLDMGYFLGDCYLIARFQDELVG
                     TTMRKAYLKGYARTAKGTINYSKVTASIGAHLVMWTDFMKWGNYEEREEFVKKGVEALH
                     DAWEDNNDGEITSVLVNEASST"
     gene            complement(2004..4114)
                     /locus_tag="CVT25_004281"
     mRNA            complement(join(2004..2066,2123..2165,2234..2315,
                     2385..2468,2532..2832,2894..3699,3754..4114))
                     /locus_tag="CVT25_004281"
                     /product="Psilocybin Transporter (PsiT)"
     CDS             complement(join(2004..2066,2123..2165,2234..2315,
                     2385..2468,2532..2832,2894..3699,3754..4114))
                     /codon_start=1
                     /locus_tag="CVT25_004281"
                     /product="Psilocybin Transporter (PsiT)"
                     /protein_id="PPQ83222.1"
                     /transl_table=11
                     /translation="MAPVDGTSDERTSLLSGRAQSVPKSTTTTERQSRSSRKSPWVSPV
                     TIITIITLVYRLATTLLTTTTIRVLHKIACQLWFHVNDPDAFPGGHIPEQSCATPGVNK
                     YYSMMISTTTIVDGLGGIFGTGVASYLSSRVGRKPVLIFLLACTMTDHLAILTVQNIYG
                     WTQFAIFGLIAIVETIGNENTTVFLVSMYIVDITEAEQRYAINPIPMCFSRYELIFLRQ
                     NCCSEFDYRVACARYLCHTTFLLGYFLRCRVGGALAYSIGGFITTYSHSDSIVYVISFV
                     VVGLVLTFTAFVLPESFSAERRELLRLKRLAETPTVSHTLVQKVKAIAAVALEPLELLK
                     PTYNPLTGKPNRRLVYCSVHTFIVTVADAYAAPAMLIFFTTQYSYTPAQVGYVMSTYSF
                     SSVFVLAIGLPLVIRWLKPLYSRTQAKSIPEEDENNEAIDPVDRNEPLQEVVVSGTSDN
                     MDVHITVISWAIESLTYIGLGTMGTFYGQLLAVASVGVGSGRIPGCRSLVAASVDPLKQ
                     GEALASVEMVSNVGRIISPMIMGTIMTATISTNPQMIFYVHAAIVAVGAPVLFLVRDSD
                     RYQ"
     gene            6855..8895
                     /locus_tag="CVT25_004275"
     mRNA            join(6855..7056,7105..7213,7265..7480,7540..7685,
                     7746..7861,7926..8043,8110..8123,8179..8462,8518..8655,
                     8754..8895)
                     /locus_tag="CVT25_004275"
                     /product="Dimethyrltryptamine 4-hydroxylase (PsiH)"
     CDS             join(6855..7056,7105..7213,7265..7480,7540..7685,
                     7746..7861,7926..8043,8110..8123,8179..8462,8518..8655,
                     8754..8895)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 165.9; E-value: 2.5e-50)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="CVT25_004275"
                     /product="Dimethyrltryptamine 4-hydroxylase (PsiH)"
                     /protein_id="PPQ83216.1"
                     /sec_met_domain="p450 (E-value: 2e-65, bitscore: 210.3,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPLTTMIPIVLSLLIAGCIYYINARRIKRSRLPPGPPGIPIPFI
                     GNMFDMPSESPWLIFLQWGQEYQTDIIYVDAGGTDMIILNSLEAITDLLEKRGSLYSGR
                     LESTMVNELMGWEFDFGFIPYGERWREERRMFAKEFSEKNIRQFRHAQVKAANQLVRQL
                     TDKPDRWSHHIRHQIASMALDIGYGIDLAEDDPWIAASELANEGLAVASVPGSFWVDTF
                     PFLKYLPSWLPGAEFKRNAKMWKEGADHMVNMPYETMKKLSAQGLTRPSYASARLQAMD
                     PNGDLEHQERVIKNTATQVNVGGGDTTVGAVSAFILAMVKYPEVQRKVQAELDEFTSKG
                     RIPDYDEDNDSLPYLSACFKELFRWGQIAPLAIAHRLIKDDVYREYTIPKNALVFANNW
                     YGRTVLNDPSEYPNPSEFRPERYLGPDGKPDDTVRDPRKAAFGYGRRVCPGIHLAQSTV
                     WIAGVALVSAFNIELPVDKDGKCIDIPAAFTTGFFR"
     gene            complement(9599..9949)
                     /locus_tag="CVT25_004291"
     mRNA            complement(9599..9949)
                     /locus_tag="CVT25_004291"
                     /product="hypothetical protein"
     CDS             complement(9599..9949)
                     /codon_start=1
                     /locus_tag="CVT25_004291"
                     /product="hypothetical protein"
                     /protein_id="PPQ83231.1"
                     /transl_table=11
                     /translation="MILHTDSRTNVQMNRVGRSLKHQRSSYTLKPVAQGGNLDGVLRTN
                     TQREGKDYPSPPAHYWCWGKEPSRGFRSSSVIRNGGVFNERDKVSGVLAKMRNWDISAE
                     AAIELVQPTHRQ"
     gene            10744..12824
                     /locus_tag="CVT25_004274"
     mRNA            join(10744..10945,10993..11101,11157..11372,11423..11568,
                     11629..11744,11806..11923,11998..12011,12086..12360,
                     12427..12564,12683..12824)
                     /locus_tag="CVT25_004274"
                     /product="Dimethyltryptamine 4-hydroxylase (PsiH)"
     CDS             join(10744..10945,10993..11101,11157..11372,11423..11568,
                     11629..11744,11806..11923,11998..12011,12086..12360,
                     12427..12564,12683..12824)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 182.1; E-value: 3.2e-55)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="CVT25_004274"
                     /product="Dimethyltryptamine 4-hydroxylase (PsiH)"
                     /protein_id="PPQ83215.1"
                     /sec_met_domain="p450 (E-value: 6e-71, bitscore: 228.5,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPLTTMITILLSLLLAGCIYYINARRVRRSHLPPGPPGIPIPFI
                     GNMFDMPSESPWLTFLQWGRDYQTDILYVDAGGSEMIILNSLEAITDLLEKRGSIYSGR
                     LESTMVNELMGWEFDLGFITYGERWREERRMFAKEFSEKNIRQFRHAQVQAANRLVRQL
                     IKTPGRWSQHIRHQIAAMSLDIGYGIDLAEDDPWLEATQLANEGLAIASVPGSFWVDSF
                     PSLKYLPSWLPGAGFKRKARVWKEGADHMVNMPYETMKKLSAQGLARPSYASARLQAMD
                     PNGDLEHQEHVIKNTATEVNVGGGDTTVSAMSAFILAMVKYPEVQRKAQAELDMLTSKG
                     LIPDYDEEDDSLPYLTACVKELFRWNQIAPLAIAHRLIKDDVYRGYTIPKNALVFANTW
                     AVLNDPEEYPDPSEFRPERYLGPDGKPDHTVRDPRKAAFGYGRRTCPGLHLAQSTVWIA
                     GATLLSVFNVERPVDRTGKPIDIPAAFTTGFFR"
     gene            complement(13552..15618)
                     /locus_tag="CVT25_004287"
     mRNA            complement(join(13552..13693,13732..13875,13945..14228,
                     14297..14828,14888..15183,15210..15233,15286..15392,
                     15471..15618))
                     /locus_tag="CVT25_004287"
                     /product="Psilocybin Transporter (PsiT)"
     CDS             complement(join(13552..13693,13732..13875,13945..14228,
                     14297..14828,14888..15183,15210..15233,15286..15392,
                     15471..15618))
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 41.9; E-value: 8.4e-13)"
                     /gene_kind="transport"
                     /locus_tag="CVT25_004287"
                     /product="Psilocybin Transporter (PsiT)"
                     /protein_id="PPQ83228.1"
                     /transl_table=11
                     /translation="MSLERSTSPEPDEHTSLLSDTASTCSSRDDLEDPKAKQPRTPIPT
                     GQLGEPIIYSHLWPYINQFVNDIGVADGNPRNVGFYSGLIESVFAVGETVGCVPLAKSS
                     NTSPNSLLDRIGRRPVLLPSALGIAVFTALFGLSTSFTMMLILRVCAGLLAGATPIVHS
                     IVGELTDETNNALVVPLYGLITPIGFAIGPLIGGTLEHAATKYPNVFGYEFLQKYPYFL
                     PSFVPCCLAIFGVTFGYFFLQEVGTFIEFLASDLAHILSQTLPSIVKAKKRLERQKSSS
                     SISSGTSTLYGATDSHNRDAPESTAFPPDDTEDEIDSKPQSIKELIKDPSIRAVMGSGT
                     FLMFLYTSSDVLFSLYCFTAVEDGGVGLPPDKIGYAFSVAGMIAMLMQLCITPWVLRTF
                     DKAKVYKFCMCSFPLVFALMGCLNPLARTGYNEISKTIHPTTTGLLYAAIALLLLMARV
                     CVMAFPISMMLVKQSADKHSLATANGLVQVSMTIARAFCPTVARYEFFEAQGNRSLFAY
                     STSHNILGGYFWVVIMVTLSFAGVWQSMSIARVTKRQEEKL"
     gene            complement(17583..19181)
                     /locus_tag="CVT25_004289"
     mRNA            complement(join(17583..17627,17695..17784,17864..17933,
                     18007..18107,18164..18278,18339..18456,18520..18593,
                     18652..18764,18861..18936,18992..19051,19105..19181))
                     /locus_tag="CVT25_004289"
                     /product="norbaeocystin methyltransferase (PsiM)"
     CDS             complement(join(17583..17627,17695..17784,17864..17933,
                     18007..18107,18164..18278,18339..18456,18520..18593,
                     18652..18764,18861..18936,18992..19051,19105..19181))
                     /codon_start=1
                     /locus_tag="CVT25_004289"
                     /product="norbaeocystin methyltransferase (PsiM)"
                     /protein_id="PPQ83230.1"
                     /transl_table=11
                     /translation="MHIRNPYRSPIDYQALVEAFPPLRPYVTVNQDNTTSIDLTVPEVQ
                     RLYTAALLHRDFGLVIDLPEDRLCPTLLTRTPRLNYVLWVEDILKVTNTALGLSEDRPV
                     KGIDIGTGAAAIYPMLACARFKTWSMIGTEIDRKCIDTARVNVLTNNLQDRLSIIETSI
                     DGPILVPIFEATTDYEYDFTMCNPPFYDGAADMQTSDAAKGFGFGVNAPHSGTVIEMST
                     EGGESAFVAQMVRESLDHRTRCRWFTSNLGKLKSLHEIVGLLREHQISNYAINEYVQGT
                     TRRYAIAWSFTNIRLPEDLTRPSNPELSSLF"
     gene            complement(20658..21961)
                     /locus_tag="CVT25_004277"
     mRNA            complement(join(20658..21713,21770..21961))
                     /locus_tag="CVT25_004277"
                     /product="Tryptophan decarboxylase (PsiD)"
     CDS             complement(join(20658..21713,21770..21961))
                     /codon_start=1
                     /locus_tag="CVT25_004277"
                     /product="Tryptophan decarboxylase (PsiD)"
                     /protein_id="PPQ83218.1"
                     /transl_table=11
                     /translation="MGWLPASDAVFNEFMGDLTDRTCNEKYSSQVTLMQPIQDFKAFIE
                     SDPVVYQEFITMFEGIEESPRNYHELCNMFNDIFRKAPVYGDLGPPVYMIMARIMNTQA
                     GFSAFTKQSLNFHFKKLFDTWGLFLSSKDSRNVLVADQFDDKHYGWLSERAKSAMVKHY
                     NGRTFEEVFICDERSPYHGFTSYDDFFNRRFRDRDIDRPVVGGIDDTTLISAACESLSY
                     NVSHNVQSLDTLFIKGEAYSLKHLLHNDPFTPQFEHGSIIQGFLNVTAYHRWHAPVNGT
                     ILKIVNVPGTYFAQAPSTIGEPIPDNDFDPPPYLKSLIYFSNIAARQIMFIEADNKDIG
                     LIFLVFIGMTEISTCEATVSEGQHVNRGDDLGMFHFGGSSFALGLRKDCTAEIFETFKE
                     SGTVIKINDLVAAVKK"
ORIGIN
        1 ttatcacgag tagaagggcc atcataatta gtagacagct gtggaatatt tacaatagtc
       61 ctgctcagtt ctaaagttgt actgagtctt tgcgcgtaac ataaagtagc catacggcga
      121 aattgaataa gaccgcgcgg tgtttgaact actgaatctc aatgccgatc ggcttatctc
      181 tatatccatg tcgttctctt tagaaatggg atttaatccc aagatttaga ggtttgggag
      241 cattgagact taaagtgatt aatgaagttg acgcaacaag taattagaag tgtttaacta
      301 tcaaaaccat cagtcgcatg cttaacaagg tccactcaaa ttaaccctat ggtgggatta
      361 attagagacc cgacaaagct acattctcat atgcaacatc actacgactc agatgaaggc
      421 tctttactcc cgacacgaga ggctggtttt aggagcctgc attgttggta tgcgcaaaga
      481 aacgcaactt tagaattgat tcctagttta agtgcttgac gcttcgttca ctagtacaga
      541 cgtaatctcc ccgtcgttat tgtcctccca cgcgtcatgt aatgcctcca cgcccttctt
      601 tacaaactct tccctctcct catagttccc ccatttcatg aaatcagtcc acatgacgag
      661 atgtgcaccg atacttgcgg taactttcga atagttaatc gtgcccttgg cagtccgtgc
      721 atagcccttc aagtaggcct ttcgcatcgt tgtccctacc agttcgtctt ggaatcgagc
      781 gatcaaataa cagtccccta ggaagtaacc catgtccaaa gatgccgggc catacttaca
      841 cagctcccaa tccacgagcc atatcttctt cagctctgat ggatttccct ccacgaattc
      901 gagaagaatg tttccactcc ataaatccgc catgataagc gtttcctcgc tgttcatgac
      961 ttcccccact aggtctttca ccacagtcgg gagaaggggg tcattaatgc cgtatttagc
     1021 agcatttggt atgatggtct gatacagctg gtctgcggtt gttctcccga cgatgttgcc
     1081 agagaagaat ttgaaggcag gttgatctct cctcttgcgc cccaaattat gaagcctagc
     1141 aatgaatgcc ccaatttcag tgccgacgag gctggcgatc tctgtggaaa gtggtggttt
     1201 ggcggtagcg taatccaaca gagtcttcat cgtcccaaca tcttgcatga tcaacgcgtt
     1261 attctctacg tcgtagtgaa ggccctcagg tacagatacc cgactatcgt cgcctcctag
     1321 aacctcctga ttggctgaca tgaccttgag ggcttgatac tcgtacgcct atgcatagaa
     1381 cgcccgatga ttattagtca acggatacaa cattcttgca gagtggacta tcacacaccg
     1441 agcgttccac acctatcttg aaatcttcat ccgaagacaa gtgtggctga gcatgcttca
     1501 gaatgatgct cgtgtgacct tgataagggg cgttgagcct gatccgccag gtgacgttga
     1561 cgaaccctcc gctgaggcgt ttcactccgc tgggatcaac atccaaagac aagtgtctag
     1621 tgagatataa gagaagacct tctggagtct tgagatcgaa agccatggtg aggtgctgaa
     1681 agggaaggag gggtgtcacc atgcattcat ttaatttgaa ctgtcaagta ctgtgggatt
     1741 ctacactatt ctcagcaatg gcggcaaacg ttggttccta acgtgaggag attcgggatt
     1801 atacccaccc gaggaagaga ttaaatatgc tatatacaga atatagatga catccgtact
     1861 ggtgtctgtt acgtatacgg taaacgtcat cacggtcgtg tgctcggccc agtaaatttc
     1921 ccgaagacag gtatgtacag taagatatag tccgtcgtga tcttcaaatc tggtatatgt
     1981 gagctacgat gtacgatgac aggctattga tagcgatcgg agtccctaac gaggaaaagt
     2041 acaggtgcac cgaccgcaac gattgcctgt catagttata tttaacttaa ttagacatgc
     2101 cgaatacaag agtcaaacgt actgcgtgaa cgtaaaatat catctgtgga ttggtagaga
     2161 tagtcctgca gcacaatcat caagaatagt gtcagatatg acaatggtgt gcattgagcg
     2221 accatggact gacgccgtca ttatggttcc cataatcatt ggagagatga ttcttccaac
     2281 attcgagacc atctctacgg aggcaagcgc ctcgcctgtg atatccacgt cagatagatg
     2341 gtttggtaga ttgcagactt aaatacttaa atgccacgac tgaccttgct ttaagggatc
     2401 taccgaggca gcaaccaaac ttcgacatcc cggaatgcgt ccagatccaa caccaacgga
     2461 agcaacagct acacgataaa cggagggtga agcgacaacg atagacgatg aggaatgtca
     2521 agggaaccaa cctaagagtt ggccgtaaaa tgtgcccatg gttccaagac cgatgtaagt
     2581 caacgactcg atggcccatg agatgaccgt aatatgtacg tccatgttat cggaagtccc
     2641 ggaaacgact acctcctgca aaggctcatt tctgtccact gggtctatcg cctcgttatt
     2701 ttcgtcctcc tccgggattg actttgcctg agttctactg tacaacggct tgagccatcg
     2761 gataaccaac ggcaagccta ttgccagaac aaatacactg gagaaactgt atgtcgacat
     2821 tacatatccc acctacgcaa cagggaatta ggaagagcaa aacgatgtag attagctagc
     2881 gaagtgtgca gacctgagca ggcgtatacg aatattgggt cgtaaagaat atcaacatcg
     2941 caggagcagc atacgcatct gcaacagtga caataaaggt atgcacgcta caataaacaa
     3001 gccgccgatt cggcttgcca gtcaaagggt tatatgtagg tttgagaagt tccaatggct
     3061 ccagagcgac agctgcaatt gccttgactt tttgaaccag agtgtgtgat acggtaggag
     3121 tttctgcgag tcgcttgaga cgtaataact ctctcctttc cgctgagaat gattcgggga
     3181 gtacaaaggc agtaaatgtt agtaccaagc caaccacgac aaatgatatc acgtatacga
     3241 tagaatcgga gtgtgaataa gttgttatga atccgcctat tgagtaggca agggcgcctc
     3301 ctacacgaca tctcagaaag tatccaagta aaaaggttgt gtggcacaaa tacctagcac
     3361 aagccaccct gtaatcgaac tcagagcagc agttctgtcg caagaaaatc agctcatatc
     3421 gactgaaaca cataggaatc ggattgatag cgtacctttg ttcagcttca gtaatatcca
     3481 cgatatacat acttacgagg aagactgtag tattctcatt cccaatcgtc tcgacaatcg
     3541 caatcaagcc gaatatcgcg aattgtgtcc atccatagat attttgaaca gtcagaatag
     3601 ccagatgatc ggtcatagta caagcaagca ggaatatcag cactggcttt cttccaactc
     3661 gtgaggacaa gtaactggca actccggttc caaatatgcc taaaaatgtc tacttttaga
     3721 acgaattaga acgacattca agatgacaat taccaccaag gccgtccaca attgtggtcg
     3781 tggatatcat cattgaataa tatttattga ccccaggtgt cgcgcatgac tgttcaggta
     3841 tgtggccgcc tggaaacgca tccggatcgt tgacgtggaa ccatagctga cacgcgatct
     3901 tgtggaggac ccgaatggtg gttgtggtca aaagcgtcgt cgcgagtcga tagaccagag
     3961 tgattatcgt gatgattgtc actggcgaca cccaagggga ctttcgggaa gaccgcgatt
     4021 gtcgctcggt tgtagtcgtc gatttcggca cagattgcgc tctgccagat aacaaggatg
     4081 tccgttcatc ggatgtacca tccacagggg ccatggtgaa aaatgatact aaacaccctc
     4141 caggtcaacg cgatggttca agatagataa gaagtagagc tgtaatgtac tcgcatcgtg
     4201 gagcgcgacc gctgtaacga ttgactgaca cagtggctga gtaagtggct agtgttgcga
     4261 atcggcacac agaggaactc gaaagacggg ttttacgttt aagaattcac tggggactcg
     4321 tacaagtaga gctagggttt atatagatac tcgaagagtc ttaatggaaa taatgaatga
     4381 gtgaaacagt ttaagtaagg aacagaaaag ttgtatacta aaggattaga gtccaagcta
     4441 ggcacaggaa atgaggaatt tggagaaatc atatgacaaa taggaagcgg cgatgaccga
     4501 tccgttacaa ccgtttttca ctacgaaaac gagtctgttc aaatggagct tttcgaaccg
     4561 ttttggtggg ggtattacag tgatgtgcga gttacgcccc gaagttatat aactcgccga
     4621 taattatggc gagttactaa ctagttatga gttatcacta actttgatga tgggttatta
     4681 catagccacc gggttgtggg ccggtgcatt gatccagagg gaaatagttt agtccatgtc
     4741 atcaatactg ttacgagtcc ttctaggact cgttattata agggcgtttc ctagtgtcga
     4801 gttgtaatgg ttattgagcc ggcaatcaac ggcatgaaat tgattgattg ttcccatcaa
     4861 ttattancag agggaaatag tttagtccat gtcatcaata ctgttacgag tccttctagg
     4921 actcgttatt ataagggcgt ttcctagtgt cgagttgtaa tggttattga gccggcaatc
     4981 aacggcatga aattgattga ttgttcccat caattattat tatgtaattc ttgctatcgt
     5041 ttctggtcat tctttataat aacagaaatc aaacttcatt gtttaagtgt ttaaataaaa
     5101 gagctagtct actattttat gttaaggtaa aataaaaaaa gacctcatac cttgaatcaa
     5161 gcgcaatgat gcatggaagc agtaagtctt agcactctta atgttaaatc acaaaactgt
     5221 ataactatag cataaagatg attaaatcaa ggttaaaaac agacatggac atagggatgg
     5281 actcgtacct gccatgtgta agcaatggcc ctctttacaa gttagtaact agttataact
     5341 tagttataac tttgatcgct gcataactct aactcgatca aatagttagt acccgcacat
     5401 cactggggta ttacacagca ggcctccttc attgaaccat tgcgcactgc gcgggcggct
     5461 ttaagtatgt attgtcagtc gaacactggc gttattacat agcggacccc gtatgcacat
     5521 tgtactgtgc tgcggaagag tataaaaaag attgaaaaaa agagatatgt acatgaagga
     5581 agaaacagaa acctgggaac tttgccggcc aggcatagaa tgtgtctaaa tgaaccacat
     5641 gggtcagcga gagccgtttc cgggggtagg acactggagc gcccttcgag tcacgatagt
     5701 ggtatgatcc tgaggagacc tatcgcaggt tttgaaggct agagcttttt tacgcacaac
     5761 tcagctaagt accttgggta tattcaaatg ggcgttttaa aaaaatattc cacatgtgta
     5821 tgccagggct cagcatgacg ctctccccgt gccactgcat cctcgatgca taggctgcat
     5881 aggcagaaat caagggggac catggttgga tatcggactc caaattcatg caaaagaagc
     5941 gatgaagagg tatgaagaga aagtcgacag tccatcttgt tgtgcaggtc ttcggcagcc
     6001 ttgcatggaa ttggagggtc aatttcaaat caacggcggc ccttgctgag ttgttggcca
     6061 aggctcttca tatataccaa gagatatgaa tccacgtgtc tctgagccgg tgtctattga
     6121 taatgttgtg gatacttttc tgtatcgcga cagctttata cacatcagga tcgattcctg
     6181 gagccagcag ttctctctga agataatttt gagaagatca gtatgtagca atctctgata
     6241 tctggaagcg tgcctttggt tgttgaagta agacgagagc ggagaaagtc acggcagcat
     6301 gcagtttggt tcgatgcaga gcataggcga tggagtaggg acgctttgct agagacaggc
     6361 ccgaagccag tggataatcg ggacaggtga acaggtgaat gatgaccgca gtgaatcgtg
     6421 gggcgtacgt tacgcaccac gcacattact ggacgaacga gcatacccaa gttgaccaac
     6481 ttctggccaa aaaaaaagtc cgagtaagcc gatattatcg tactggtgta tgtacttatt
     6541 agcaagggag catagaattc gtgttacata ccggtgccca gccgacagcc gtcctgacct
     6601 agcaagcaac ctacccaaac atgtagcaga tgccagagca gaggtccgat gtggaagtct
     6661 gatgactgat gcaaccgtgg cgctcccgcc tgagggacgc cgttcagatc cgcggatgac
     6721 tgggggtcca aataggttgt tcggcggatt tttattttga gaaatcgagt gtgggcttaa
     6781 ataggccaaa gaattgatat tctatgtcta tgcgcctctc gttccgggtt aaaaaaaaac
     6841 gtcctctgag aaccatggca cctctcacca ccatgatccc catagtactc tcgctcctca
     6901 tagcaggatg catatactac atcaacgctc gcaggataaa gcgttcccgc ttaccccctg
     6961 gaccgcctgg catacctatc ccattcattg ggaatatgtt tgatatgcct tcagagtctc
     7021 catggttgat ctttttacaa tggggacagg aatatcgtaa gtcagcgtgg tatgctttgg
     7081 ccaacgttta atcaacttcg gcagaaaccg acatcatcta cgtcgatgct ggaggaacgg
     7141 acatgattat tctgaactca ttggaggcta taaccgactt gttggaaaag cgggggtccc
     7201 tgtactccgg tcggtaagtc gttactctca tacagatgac ttcttgttga tgagaacgcg
     7261 tcagactcga gagcacgatg gtgaacgagc tcatgggatg ggagttcgat tttggattca
     7321 taccctacgg cgagagatgg cgcgaagaaa ggcgcatgtt cgccaaggag ttcagcgaga
     7381 aaaatataag gcaattccgc cacgctcaag tgaaggctgc caatcagctt gtccggcagc
     7441 tgacagacaa gccagatcgt tggtcacacc acatccggca gtgagtgacc cctatttggg
     7501 aagagatgaa tagatgcttg actatcgagt atgatacagt cagatagcgt ctatggctct
     7561 ggatattggc tatgggatcg atctggccga ggatgatccc tggattgcag catctgagct
     7621 agcaaacgaa gggctcgctg ttgcatcagt gccgggcagt ttctgggtcg acacattccc
     7681 tttccgtgag tgcacttcta atataatctc aaggtatcaa tcaccgacat ttgagtgtct
     7741 ctcagttaaa taccttccgt cctggcttcc aggtgctgaa ttcaagcgca atgcaaagat
     7801 gtggaaggaa ggcgctgacc atatggtgaa tatgccatat gaaacaatga aaaaactgtc
     7861 tgtaagtcgt actccatatt acctcgtgaa tcatcgggca gattaaattg acagttattc
     7921 tcaaggctca aggtttgacc cgaccctcat acgcctcggc tcgcctccag gctatggatc
     7981 ctaatggcga tctcgagcac caggaacgtg tgatcaagaa tacggccaca caagtcaatg
     8041 tcggtaagta aaaataacat cccatcggca attaaagtac agggcgctaa ttgattattt
     8101 ttggtctagg tggcggtgat acggtaaata aatcttccag ccacaaaccc gaccactgat
     8161 acgtttgtct aaattcagac tgtcggtgct gtgtcagcat ttattttagc tatggtcaaa
     8221 tatcccgagg ttcaacgtaa agtccaagct gagctggatg aattcacgag taaaggccgt
     8281 atcccagatt acgacgaaga taacgactcc ttgccgtatc tcagcgcatg ctttaaggaa
     8341 ctctttcgat ggggccagat tgcacccctt gctattgctc atcgacttat caaggatgat
     8401 gtttaccgcg agtatactat acctaagaat gctttggtct tcgctaataa ttggtacgga
     8461 cggtatattt atgatatatg cgtgtggtag acgacttaca ggctgtcatg tttccaggac
     8521 tgtactgaac gatccctctg agtatccaaa tccctctgag ttccgtccag aacgatatct
     8581 cggtcctgac gggaagcccg acgatacggt tcgtgatccc cgcaaagcag cattcgggta
     8641 tggtcgtcgc gtttggtaag tatgtttttt gaacacatca tgttggacaa gtctttccat
     8701 gagtcgcctg ccaatcttat gcactagctg acgtgtggca ttatgttatg tagccctgga
     8761 atccaccttg ctcagtcgac ggtatggatt gcaggggtgg ctcttgtgtc cgcgttcaac
     8821 atcgaactgc ctgttgataa ggatgggaaa tgtattgaca taccagcggc gtttacaaca
     8881 ggatttttca ggtaattcat tcattcgcct gatgccctct tcttataatt cacaattcaa
     8941 accgcatctc actcactacg accttgggac tatgcagaca tccggaacct ttccaatgcc
     9001 gattcgtgcc tcgcaatcag gagggtctca aatctgcgtc tcgattctga tgtgtttgtc
     9061 tcggctaggc atttggaagt taaactcggc aatggcacgt ataagtatgt tcagaatcaa
     9121 gggcaggagg agcaggagta gagataaagg agatcggaca gtggattcat aatatacttt
     9181 gatatcatag gcccatacac atgttgagag agcaaactga caaggacagc gtagcaaatt
     9241 aaatgccaag ttaccctgac atggcggacg atttggcggc gacggctttg ttcaatgttg
     9301 cagtccgcag ttagggagat gggaaaatga ttatgtaata agtgctcacg taatgtactt
     9361 cgagactcgc tgtcggatca acttcatcac caggactcgg cttgaaatgt agccaacctt
     9421 gaaccaatac catcaccctt tctgttgcag ccctatcctc taagaaggcc aagctcgcgc
     9481 agggagtggg ggattatcca ctcactgttg acctactggt tgaagttcat gttgagtcca
     9541 tgtaagttga cttaatgccg tgccatcaat acattctaat gattaaacca gcttgcctct
     9601 actgcctatg ggttggctga accaattcta ttgctgcttc tgccgatata tcccaatttc
     9661 tcatcttcgc caacaccccg ctgaccttat cccgctcatt gaatacccca ccgttccgta
     9721 taaccgaact actgcggaat cccctcgatg gctcctttcc ccagcaccaa tagtgagctg
     9781 gaggagaggg atagtccttg ccctctcgtt gtgtgttcgt cctgagcaca ccgtccaggt
     9841 tgcccccttg cgccaccggc ttcagtgtgt agctactgcg ctggtgtttc aaggatctac
     9901 ctaccctgtt catctgcaca ttcgttcgag aatcagtatg gagaatcata gattgtgtat
     9961 tcagtgtaag ggccttactc tctttagtcc cacctaattc gatcgatgta attactccag
    10021 cgttcttcgg tgctggtata ctggttcgaa cgccggctgg ggcttcctca agctcaattc
    10081 cccgtcattc tcatattctg acgttgggta atagtcattg gtaaagtctg agcctgattt
    10141 caagacgaac tggtagggac aaggatacaa aaggcctcct tgaaggtcta cgtacttact
    10201 aacacggcta cgcacagaca gccaaagacc cttttaatta cgcgacagtc accgcaggca
    10261 tcggcgcata tctcgtcatg cgggttgatt ctatgaagtt ggggaacgat gaggagatgg
    10321 aagcgtttgt gaagaaggcc ttggaagcct ttcatgatgg gtgggggaca ataaagactg
    10381 ggagattacg tctgcgctag ccgaggaagc atgtagcaac acgttgtact tactatcttc
    10441 aaaactggac tactgattac ggtacccatt ctgctcgtgt gagcgataat gaataaactt
    10501 taagaacggg caattcagcc ttctctcaca ccatgcaccc tgacggcctt gcagttctgc
    10561 cgatgactgg gcctggaggt gatgtaacat tgtcctaata ggttgttcgg cacggttcta
    10621 tctttagaaa tagggtgtgg gcttaaatgg gccaaagaag tgatattcta ttcggctctg
    10681 ctcaatgtct atgcacctca aggtatctca cgtccaggtt aaaagaaacg tcttctgagg
    10741 acaatggcac ctctcaccac catgatcact atactactct cgctccttct agcaggatgc
    10801 atatactaca tcaacgctcg cagagtacgg cgctcccacc tgccaccagg cccgcctggc
    10861 atacctatcc ccttcattgg gaatatgttt gatatgcctt cagagtctcc atggttgacg
    10921 tttttgcaat ggggacggga ctatcgtgag tcaacatatg ctatgatttg cacgtctaat
    10981 cgggttctgt agaaactgat atcctctacg tggatgctgg gggatcggag atgattattt
    11041 tgaactcatt agaggctata accgacttgt tggaaaagag ggggtcgata tactccggtc
    11101 ggtaagtcgg actcgtcacc acatctcata gcgatcatgt gatgaagacg cgctagactt
    11161 gagagtacga tggtgaacga gctcatggga tgggagttcg acttgggatt cattacctac
    11221 ggcgaaagat ggcgcgaaga aaggcgcatg ttcgccaagg agttcagcga gaaaaatatc
    11281 cggcaattcc gccacgctca agtgcaagct gccaatcggc ttgtcaggca gctcatcaaa
    11341 acgccaggtc gctggtcgca gcacatccgg cagtaagtgt cctccgtttc agaaatgacg
    11401 ctgaatactg agaatagtgc agtcagatag cggctatgtc gctagatatt ggttatggaa
    11461 tcgatctcgc agaggatgat ccatggcttg aagcaacaca gctagcgaac gaagggctcg
    11521 ccatcgcatc agtaccgggc agtttctggg tcgactcatt tccctcccgt aagtgcgcct
    11581 cttctataat aagaaaccag ttgccgacta tctgctattt tctctcagtt aaataccttc
    11641 cttcttggct tcccggtgct ggattcaagc gcaaagcaag ggtatggaaa gaaggtgccg
    11701 accatatggt gaacatgccc tatgagacga tgaaaaaact atccgtaagt cttactttat
    11761 ggtaactcat gaaccattgg gtagaatgaa ctggttatta tcaaggctca aggcttggcc
    11821 cgaccatcat acgcctcagc tcgtcttcag gctatggatc ccaacggcga tcttgagcat
    11881 caggaacacg tgatcaaaaa tacagcgacg gaggtcaatg tcggtaagaa taattacatt
    11941 cgtcggctac ttaaattctg ggcgctaatt ataatcaatt ggctgttttt tgtctaggtg
    12001 gcggtgatac ggtaaatcaa cccccagtga ctaacccgat tgtacaccct cttacctatt
    12061 cgctttgaca cttttcccaa ttcagaccgt ctctgctatg tcagcgttta ttttggctat
    12121 ggtcaaatat cccgaagttc aacgcaaagc ccaagcggag ctggatatgc tcacgagtaa
    12181 aggccttatc ccagattacg acgaggaaga tgactcatta ccgtatctca cggcatgcgt
    12241 taaggagctc tttcgatgga accagattgc acccctcgct atcgcgcatc ggctcattaa
    12301 ggacgacgtt taccgcgggt atactatacc aaagaacgct ttggttttcg cgaatacttg
    12361 gtacggacgt tctatatttc tgatatgtaa gtagtacatc cgcttacggg tttacactat
    12421 ttctagggca gtactgaacg atccagaaga atatccagac ccctctgagt tccgcccaga
    12481 acggtatctc ggtcctgacg ggaaacctga ccatacggtt cgcgatcccc gcaaggcagc
    12541 attcggctat ggtcgacgca cttggtcagt atgcttcgaa taaaccgtat ttgacgactc
    12601 ttatcatgag ttgcccgccg atctgatgca ccgactaacc tgtggcattc tttgtttcta
    12661 tatacttatg cttattcttt agccccggac tccaccttgc gcagtcgacg gtatggattg
    12721 caggggcgac tcttctgtcc gtgttcaatg tcgaacgacc tgtggatagg actgggaaac
    12781 ctatcgacat accagcggcg tttacgacag gatttttcag gtaattcatt catacgcttg
    12841 aatgctttcg ccttgtaatt caaaaattca tctcactcac gacgaccttg gggctatgca
    12901 ggcatcctga acctttccaa tgccgattcg tgccccgcac tcgagagatt cccacatctg
    12961 tatccggcgt ctgatgtatt cggttcccag gttagactcg gcaatagcat gtatatatgt
    13021 agcaccgagt ctatttgata gatgcggata cacatgatcc taagatttaa taattaagta
    13081 catatgatgc aataaacgcc agatgcaagg gtctccactc tgaaggacag actgaataga
    13141 agtcgccttc gattcgtggc tagatcgccc tccattttgg tccttccaat ctcccctatc
    13201 actaatatat ctggtcgtgt gactcgcgaa aagaagcaag ggttgtaaaa gtatgcatta
    13261 aatcaatttt tattggttta tgcttgaatg agatattcta agtatatagt atgaacagaa
    13321 taactgcaat gtgatgaaga taacaagtat gcaaaaatgt aatgtacgaa tatgacgaca
    13381 catagaaaac aaaaaacaaa ccaacgaaga tagagtacag taatgcaatc caactgaata
    13441 cagaaggata agtgatcaaa ggaccgtgtc taataaagga aagtgtgggt ttaataacaa
    13501 agggaaatgt gcaaggacat cttatgggga aagggaaagg ttagagggct tttatagctt
    13561 ctcttcctgt cttttggtga cgcgggcgat gctcatcgac tgccagacgc ctgcgaagga
    13621 caaggtcacc ataatgacga cccagaaata accgcccagg atattatggc ttgtggaata
    13681 agcgaacagc gagctaaaag atgtgagagc agttggtcag tcaaagctta ccgattgcct
    13741 tgtgcttcaa agaattcgta cctagcgacc gtagggcaaa atgctctcgc aatggtcatc
    13801 gatacttgca ccagcccgtt cgcagtggcc agcgaatgtt tatcagcgct ttgcttaacc
    13861 aacatcatac taatcctgaa ataaaaaaga aaccttcatg aacaacagta cgcgtcgatt
    13921 ggcttctaaa ataagaacac atacgggaaa gccataacgc agacacgcgc cataagaagc
    13981 aagagagcga tagcagcgta cagtaaaccc gtagtcgtcg ggtggatagt cttagagatt
    14041 tcattgtacc ccgttcgcgc gagcgggtta agacatccca tgagcgcaaa gactaacggg
    14101 aacgagcaca tgcagaactt gtatacttta gccttatcga atgtacggag aacccagggt
    14161 gttatgcaga gctgcataag catagcaatc atgcccgcaa cagagaaagc ataaccaatt
    14221 ttgtcgggct acattaggaa taaagacaat aagaacgcgt taccaagcca agaatcatta
    14281 taaggttttg acttacaggt aatccgactc ctccgtcctc gacagcagtg aagcagtaga
    14341 gtgagaaaag aacatcggaa ctcgtgtaga gaaacatcaa aaaggtacca gaacccataa
    14401 cggcacgtat agaagggtct ttgatcaatt ctttaatgct ttggggtttg gaatcaattt
    14461 cgtcttccgt atcatccgga ggaaatgcgg ttgactctgg cgcatccctg ttatgactgt
    14521 ctgtggcacc ataaagagtg gaggtccctg acgaaatgga cgacgaggac ttttgacgtt
    14581 ctagtctttt cttagccttt actatactgg gaagcgtctg tgacagaatg tgagcaagat
    14641 ccgaagccag gaattcaatg aaagtgccca cttcttgcag gaaaaagtag ccaaacgtga
    14701 cgccaaagat ggctaggcag caaggaacaa aggacggtaa aaaataggga tatttttgaa
    14761 gaaactcgta accaaagacg ttgggatact tagttgcagc gtgttcgagg gttcccccga
    14821 tcaggggcct ttcgagaaaa ggaagtcagc gaacgaccac gcgccatatg ctagataaaa
    14881 tgttcacccg atagcaaaac caatgggtgt aatcaaccca tacaagggca ctacgagggc
    14941 attattggtc tcgtctgtaa gctcccccac aatagaatga actatagggg tagctccggc
    15001 tagaagacca gcgcaaaccc ggagaatcaa catcatagta aacgaggttg acaaaccaaa
    15061 cagcgctgta aatactgcta tgcccagtgc agacgggagc agcactggcc gacgacctat
    15121 tctgtctaga aggctattag ggctggtgtt actcgacttt gcgagaggta cgcacccgac
    15181 agtcttgata gcacgaaaat agaacacact tctccgacgg caaatacact ctcctataga
    15241 ggttgttagt aattgcgagg cggaaagcta aacgaaatta cttacgatca acccactgta
    15301 gaacccaaca ttacgagggt tcccgtcagc gacgccgata tcattaacga attggttgat
    15361 gtatggccat aaatgactgt atattatggg ttctgtaaac ctgatagaga ataaaactgc
    15421 aaatacgatg cgttcagcgc gtttgatatt ttgatgagct gagcacttac caccgagctg
    15481 tcctgtgggt atcggcgtgc ggggctgctt cgccttcgga tcttcaaggt cgtctctcga
    15541 cgagcaggta gacgcagtat cggatagcag agacgtgtgc tcgtctggtt caggacttgt
    15601 tgagcgctct aatgacatag gaggttggta agagagaggg aaaaaagctc cagcatttcg
    15661 tcagagtttc gctggctaaa tgcaaatctt taattagctg tcaatttaga gcaactcggc
    15721 ccacattcgg cgtgggtgtg catttccatt gtccgtgttt gcccctatag gagatctagc
    15781 ccaaaaggtg ctcaatttag tgatggcatc aatcggctgt tcggccgacg gtcaaatatc
    15841 actggctggg agcgtcaact ccggtgtaaa tactccatcg gaatgtatct cgctgcaatc
    15901 tgggtgtcac tgccttctag catttgtagg cgacgtgcta atgttcgtcg ggtcccggcc
    15961 tgctccgaac aagagatgag catgggaagt atgacgactc actgcatttc cggccagaac
    16021 cttgtgcgag caaatcggaa gctagcgcgt attgagcgcg cggcgctaaa atgttggaaa
    16081 taacatactt aaactgtaat ggaatcaagc aatatgtaag cctgtggcta taggtgctac
    16141 ggtgtaatca ggtttgcgat ttctgagtta cttgtccaaa aaagccgatg aatgaagatt
    16201 cgaacacctc atggcaacct caggtcacct gtctggctag aaggatcaaa tccgactgtc
    16261 cgagggctgt cctcttcata tcaatgggat agcgttagaa gaaatgagtg ttcgattctt
    16321 ggtgcagcac gcgatggcac cgactgctgc caattggcta ctgcaactta aagcttagga
    16381 taagaaggag gaaaggggtt tttagaattc gtcatactag agactcgagt tcctatcatg
    16441 ccggggtttc tgtagcttcc tctacctagt gtttaattga agatccgaga acgatgggtt
    16501 tctgggtcca ctgagaatta ttttggagca ctctttttct ttttctggtg aaagaaccca
    16561 tgttcgaatt atatcgttga ctggtgtagc cacagagtac ttgtggggca cgccagtggg
    16621 cgcaaggagc gttgagagga agttaatata tccgataatg gaatcatcat ttacacgctc
    16681 cgaggagatg ttgccctgta gccatttctg atgatgataa gtgggtgtca ttgttcgatt
    16741 ggcacaattt aatttccccg ttaagccaaa tcccacggca gtgttcccaa tgctctccgt
    16801 tgctctccgt tgtctctccg gttcggtggt gggttcaacg ttcatagttc gatacatcca
    16861 tacaatgtac tgtataacat tcaatataaa ttgtcgaata cgagactcat tcttcaacag
    16921 gatttgagag attctctaaa gactccatac atcttattga gaaattgatt aggaactcct
    16981 acagtaaatc aggtgaaatt atccattcct acttacagat atctggagac acagacttca
    17041 actcaataaa ttttgacacc catgaattga catttatttg cattcttaat ccttgattgc
    17101 aagaaaatga cttctttatg actttgcata gaccgagaca aagttttaga gattcgtaca
    17161 tactgaaact ctctatttct gtgcaataag tagcttgaga aacgacaaat gaaccttttt
    17221 gttcagattg attaagtgtc ctaattgtat taccatcata ctaatagcat agatttcttg
    17281 taggtagatg cagtgcgtct aagtattgtt tgtctactgc agatattcag acgacccctc
    17341 tacggccggc aattatattc caatcgtatc taatctaatc aaaaatggtc acgtgactgg
    17401 gatagaatta taaccaatcg aacgatgcaa aagaaatata ttgttcgaag ttatctgaat
    17461 agtctacaga gcacagagcc tatcttcatc caagaaccgc agaaatatga ccaaatcatt
    17521 gataaagact cttctctcct tcctccaagg ggttacttgg atgtgggtat caggttaacc
    17581 ttctagaaaa gagagctaag ctcggggtta gatggacggg tcaaatcctg tcaaattaat
    17641 cggtttatca ttcatcagtc ataaagatag agactcgaat gacgcgagac gcacttcagg
    17701 tagtcgaatg ttagtgaaag accacgcaat tgcatatcga cgagtggttc cttggacgta
    17761 ttcgttgatt gcatagttac ttatctgcat cagttgcaat ttaagttccc tagttagtga
    17821 gcgagggaaa ggaagcgaac agagcactgg cagggaaaca tacctgatgt tcccgcagca
    17881 accccacgat ttcgtgcaaa gacttcaact tccccaagtt actagtgaac catctagaac
    17941 atcaaaagat taacgtgatc agtggtcaca cgacaaggaa tacaaaggaa agaagcacgg
    18001 gcgtacctgc atcgtgttcg atggtccaag ctttcgcgaa ccatctgggc cacgaaggcc
    18061 gattcacctc cctcggtgga catctcgata accgtgccgg aatgcggcta ttaaaagtaa
    18121 tcagataatc gtgatgggat caaaaaggag acagaaagca tacagcgttc acgccgaacc
    18181 caaacccttt tgcagcatcc gatgtttgca tatcggccgc accatcgtag aatggaggat
    18241 tacacatcgt gaaatcgtac tcgtagtccg tggtcgctct atagaatatt tcaagaatag
    18301 ttagatccgc ttatgaagag aacgtaaagc gcacatactc gaagatgggg acaagtatag
    18361 gaccatcaat ggacgtttct atgatcgaaa gacggtcttg gaggttattg gttaagacgt
    18421 tcacgcgggc cgtgtcaatg catttcctgt ctatctctgt gagagggatc agatatataa
    18481 atttcgagga acgcataaat agtcaaaaga tctccgtacc tgttccaatc atggaccatg
    18541 tcttaaaccg agcgcatgcg agcatgggat atatggccgc agcgcctgtt ccgctatcac
    18601 agagacagga tattggcttc agtactggag gcagagttgg gcgactctca catatctatc
    18661 cccttgactg gacggtcctc cgagagaccg agagcagtgt tagtaacttt aagaatgtct
    18721 tcaacccaaa gaacgtagtt aagcctaggt gttctcgtta gtagctataa ttaccataac
    18781 agatgctagc gagtcaccga ttgggtacct ggatgaattg ttagcaaaaa tgattgaagt
    18841 ggtgacaagt cctgacgtac tgttgggcat agacggtcct ctggaaggtc gattacaagt
    18901 ccgaaatctc gatggagaag ggcagccgtg tagagtctag gttcatactg tttcagcgga
    18961 gaaatatagg gaaaatatgg aatagactga ccgttggact tctggaactg tgaggtcgat
    19021 ggaagtcgtg ttgtcttgat tgactgtcac actatagtgc tttatatttg aatgaatgga
    19081 agtgaaaata gaatgagggc gcactatggt ctgagggggg ggaatgcttc aaccaatgct
    19141 tggtagtcaa ttggactgcg gtacgggttt ctgatatgca tggaggtaag cagggatttg
    19201 caaactagtt agagggcaat cgctattgaa ctggccctga cgactagcct tatgtaccta
    19261 acaccccagg tgatcgattt taatagatgg gtgatcgtaa agcgtgttcg taaagcgtgt
    19321 ttggacaatg agaattcgtg gagaatcgag ggtcagtttg tttttacgtt ttcaccttcg
    19381 acggcgttgt acttgaggct agaattcgct agatgcaggc ggggttcata aagatcaatc
    19441 atgtattcga tcgcctgaac agagatagac gatgccattg gttcgtgact ttcctacgat
    19501 agcactgtga cctgcccaga taagcgtgga gatgatgcgg cgaatttgcg gcgaatgggt
    19561 ttgggcatcc aattggcatc cgagtaagtt gcgagtaggt gcaacggtta caaaagtgac
    19621 gcaatcgaac gacaggaaca agacaaactg tgtgaaaagg atgcaagagg atacaaaata
    19681 ttcgtcacca gaggagaaag cggtcgcgaa ctcgagcgat ggaccgaacg tagatcagct
    19741 agcaaagccg cggcacacgt ttgactttat ttggtttgct cagattggtg ccacttaagt
    19801 cgaaagtcaa gcgccgctca tggagatcga ggttgcagga ggttgctcac gagtcggtct
    19861 tcctgatgag agttgtatta agtaatttag aagattagaa gaccagtggc actggcaata
    19921 ggagatattc atacctcatg tggcgaagcg tcatttatgg catcatcgct gtggcgtatt
    19981 ccaattatcc gagttcaagg ctcaggagcg gtctcacttc tttaccgtag aagtatagta
    20041 caactcacaa atgtggattg cataataggg tcgagcaatc gtgaggaggg gagagtacca
    20101 ttatctccca atgagcattt aatcacggtc aactcggatt aattacgagc ttcccgacca
    20161 cagctcgtta ttgtcgttgc ccgagtaagc cttttggatt ttctaattat ttatttaata
    20221 catcccctta gcagtcttat ctataaaccg aaaacgggta tttcaatttg gaatgcaatt
    20281 taatttgcac cgagaatagt aacgcattga tatgtctgaa tgtttgatat gtttttcatc
    20341 tacttgtccg aaaagtgaat gttggaacta atcaatgccg gcaaactaca aatagactaa
    20401 taatctattt atagcaaccg caagtcaaca aaaatcgctc acaagacctc aataaatccg
    20461 tcatccacta gcgccgaaaa cactttatta tctccatttt ggggttgatt ctaacaatac
    20521 atccttctca gatctggtcg gttgtcaaat gcattctttg agaaagaaaa aatcacagtg
    20581 tagtcgtaca tctatgttac ttgaatcatt cgcatttcat tgtccaaact aacgtccaat
    20641 cagaatttta gagccgacta ctttttgacg gccgcaacca ggtcgttaat tttgatgacg
    20701 gtccccgatt ccttgaatgt ttcgaagatc tccgctgtac agtccttccg caagccaaga
    20761 gcgaatgacg aaccgccgaa atggaacatg cccaaatcgt caccacgatt gacatgctga
    20821 ccttcagata ccgttgcctc gcaagtcgag atctcggtca taccgatgaa gaccaggaaa
    20881 ataaggccga tgtctttgtt atcggcttcg atgaacatga tttgccgcgc agcgatgttg
    20941 gagaagtaaa tgagagattt taagtaagga ggggggtcga aatcattatc tgggatgggc
    21001 tcgccaattg tgctaggagc ttgggcgaag taggtgcccg gaacgttgac gattttgaga
    21061 attgtgccat tcacgggagc gtgccatcgg tggtaagcgg tgacgtttag gaatccttga
    21121 atgatgctcc catgttcgaa ttgtggtgta aaagggtcgt tgtgaagtag atgtttaagc
    21181 gaataagcct cgcctttgat gaatagcgtg tcgagagatt ggacattgtg agagacgtta
    21241 tacgaaagtg attcacaggc agccgaaatg agagtggtgt cgtcaatccc accgacaaca
    21301 ggccggtcta tatccctatc cctgaacctg cgattaaaga agtcgtcgta agaagtgaag
    21361 ccgtggtacg gagagcgctc gtcgcagatg aagacttctt cgaatgtgcg cccgttgtaa
    21421 tgtttcacca tggcagattt cgctcgctcg ctcaaccagc cgtaatgctt gtcgtcaaac
    21481 tgatcagcaa caagcacgtt gcgagagtct ttcgaggaaa ggaatagccc ccaggtgtcg
    21541 aaaagctttt tgaagtggaa gttcaagctc tgttttgtga acgcagagaa acccgcctgt
    21601 gtgttcataa tcctagccat gatcatgtaa actggaggcc caagatcgcc gtagactggg
    21661 gctttgcgaa aaatatcgtt gaacatatta catagctcgt gataattcct gggctgaaaa
    21721 caaagaataa gtagggaaat gctatctata ctcagaaaaa gggactaaca gactcctcga
    21781 tcccctcaaa cattgtgatg aattcttgat acacaacggg gtcgctttcg atgaaagcct
    21841 tgaagtcttg gataggctgc atgagggtaa cctgactgga gtacttttcg ttgcatgtgc
    21901 ggtcggtcaa gtcccccatg aattcgttaa agactgcatc gctagcaggg agccacccca
    21961 tttttcgaaa ggcctccggg gttgggcata atgatgtaag cgcgctatat ttttgtatcg
    22021 cacgtagtca gtacagaaat ctaatgaaca gaaaatagat atcacatacg aagagtggca
    22081 cgcgggcatt acctgcattt ttgggcttcg agctggggta gaatgttcga acttggggga
    22141 gtatacttca tgatcttgtt aggaggcata catttatacc aagttacttt ctgactagaa
    22201 ggtaatcaag acggtggtgc aggatccaag ctgtcgtaaa aaaagacttc caggtcgaac
    22261 gtcagcgtgc attaaatttt aaagtaatgc ccccttaggt acacagagcg tggcgtctgg
    22321 ccagattgcc ggttcaccgc gacgtaatgg cgtaacttac ttgttaattg aagatcttgt
    22381 tgacataatg catcgtccta ctcaccccaa tgtggcacac gaccgcattt ctgcttcagt
    22441 actggtggta acgagtgcct taaaggcggc aaaaactgca atgaagttgt ctacattcac
    22501 cacccagatc ccc
//
