LOCUS       BGC0002215             31462 bp    DNA     linear   CON 22-MAR-2015
DEFINITION  Endocarpon pusillum Z07020 unplaced genomic scaffold C653857, whole
            genome shotgun sequence.
ACCESSION   BGC0002215
VERSION     BGC0002215
KEYWORDS    .
SOURCE      Endocarpon pusillum Z07020
  ORGANISM  Endocarpon pusillum Z07020
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Chaetothyriomycetidae; Verrucariales;
            Verrucariaceae; Endocarpon.
COMMENT     ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2024-10-17 17:09:07
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 48852
            Orig. end    :: 80314
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     gene            complement(1..849)
                     /locus_tag="EPUS_05787"
     mRNA            complement(join(1..512,567..849))
                     /locus_tag="EPUS_05787"
                     /product="hypothetical protein"
     CDS             complement(join(1..512,567..849))
                     /NRPS_PKS="Domain: PKS_KR (4-175). E-value: 1.9e-09. Score:
                     29.5. Matches aSDomain: nrpspksdomains_EPUS_05787_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     118.4; E-value: 6e-36)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="EPUS_05787"
                     /product="hypothetical protein"
                     /protein_id="ERF77218.1"
                     /transl_table=11
                     /translation="MAPRVVLITGANTGIGFQIVRSLCSSDQAYDIIVGGRSLSKAEDA
                     ISSAVKEFPSSRSKLFPIQVDIEQDDSIKHAFNEVQSKFGKLDALVNNAGAQLEAQFAA
                     GKLTERDIWNQSWNINTVGAQVMTSSFIPLLLQTPDPRLLFITSNASTLAGTENLALPI
                     DRSPPKGWPKRGFSIAAYRSAKSGMNMMMREWHRTLKEDGVKVWCLAPGFSATGLGGNP
                     EASKKMGAGDPAVAGPFIRSVLEGERDGDVGKVITKDGVQAW"
     subregion       1..31462
                     /aStool="mibig"
                     /contig_edge="False"
                     /label="PKS"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..31462
                     /contig_edge="False"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     aSDomain        complement(join(271..512,567..837))
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EPUS_05787_PKS_KR.1"
                     /evalue="1.90E-09"
                     /label="EPUS_05787_PKS_KR.1"
                     /locus_tag="EPUS_05787"
                     /protein_end="175"
                     /protein_start="4"
                     /score="29.5"
                     /tool="antismash"
                     /translation="VVLITGANTGIGFQIVRSLCSSDQAYDIIVGGRSLSKAEDAISSA
                     VKEFPSSRSKLFPIQVDIEQDDSIKHAFNEVQSKFGKLDALVNNAGAQLEAQFAAGKLT
                     ERDIWNQSWNINTVGAQVMTSSFIPLLLQTPDPRLLFITSNASTLAGTENLALPIDRSP
                     PKGWPKRG"
     gene            complement(2425..5087)
                     /locus_tag="EPUS_05788"
     mRNA            complement(join(2425..3273,3337..3861,3930..4719,
                     4805..4962,5067..5087))
                     /locus_tag="EPUS_05788"
                     /product="hypothetical protein"
     CDS             complement(join(2425..3273,3337..3861,3930..4719,
                     4805..4962,5067..5087))
                     /codon_start=1
                     /locus_tag="EPUS_05788"
                     /product="hypothetical protein"
                     /protein_id="ERF77219.1"
                     /transl_table=11
                     /translation="MAPSEKPTQSWSTHDIACTHCRERKIRCGRERPQCAHCRRDGVEC
                     EYSTPGKRVNHIKLLCNNIGGLEDRLSNIEGELSRLMTLLKAGVHQRPFMDNSTTEESS
                     ATLSIKDSLADVTSCSLPTHDQGACRHNDPIDRHHGPCTLLALCNAFSDTILSEQWTPG
                     PAPGKDQLPKSNKQEDFAKNEAVKDVLVRMCLEAGIEESFDLQPNHTPIRLPPKQFLFM
                     IQNQCFQQADYATDIFVQSSFWSNVERIYSQPFTPADKAWAICFNTIILLVLGSEVQIQ
                     NSDPIVESQFVLPFLSTVRTALNNPRVLMAPKLINVQALALLSLAAQQYYPPGFADSIF
                     AQACVLARTLGLHQTPMASDNASPEEQQERFKVFKSLYLRDKSFTISRGSFCWLPGSDC
                     SLSSQLDQSAIADPKLASRVQLAKLQEEIYRLFHPAESQRRCSIRHKTLLLRIEQSLER
                     WADTHDIFTSVNTNPRNVDLQLEFLAARISVLHGSLEPVHCDQSMFQRPDGLSISKSPS
                     LKGLNKSTSRRSSKDKTSSNDACSGSTEENANQPISLRSHRLPDTFSAHGFFLLARNLI
                     QPISTDDESQADEDMNLLQKVCACYRELEGGSQANNHTRKVGHAFGRLLQVVNLVKNDQ
                     QLQPLPTMLHQASTAHTPPSTQNFFAGQQGLSDFTDLSTASSYPAPPMPLEGFSSKNNS
                     TAATTSVSTCPSPGLLTPMELEFFSPHFEQPQSIMSPSGRKRVRLSGPNAVMDESPNSR
                     LLSELLAASPMMSFDVAAQEDIHTAVL"
     gene            complement(8394..10267)
                     /locus_tag="EPUS_05789"
     mRNA            complement(join(8394..9379,9435..9620,9823..10120,
                     10175..10267))
                     /locus_tag="EPUS_05789"
                     /product="hypothetical protein"
     CDS             complement(join(8394..9379,9435..9620,9823..10120,
                     10175..10267))
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 355.5; E-value:
                     7.5e-108)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="EPUS_05789"
                     /product="hypothetical protein"
                     /protein_id="ERF77220.1"
                     /sec_met_domain="p450 (E-value: 6.6e-76, bitscore: 245.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDSAADLRGRGSWSYSAAEYPVVAVTACSVLLILWAIAHILYNIF
                     LHPLRNHPGPKLWAATRVPWCWYQYQGILHERLLELHVKYGHTVRIAPYELSFTSDTAW
                     KTIYGHRSVEMDKDPVFRLHTPTGAQNILVADRQTHIRQRRLLSHAFSEKALREQEGIL
                     QTYVSKLLEQLSLRYTAGPLNMVAWYNFTTFDLIGDLSSGEKFGCLDKGDYVPFVRATE
                     RIAKELTFTQMLIYFGVAGVRQFFLPKAVAGQRAQNMKRAIDTVERRIQRDTDRKDFLY
                     YILAANDEKGMSRAEIHVNSFSFNIAGSESSATALSGITYHILTRSSAYSELIHEIRTS
                     FTSEEEITIASTNDLKYLEAVISESLRLYPPVAGTLPRVVPAPGETIDGIHVPTGTTVG
                     VHHFSCFRHPANFHRPDEFLPERWLPECKDVPPFDKDNRAAVQPFSFGPRNCLGKNLAR
                     AEMRLIMAKLLWRFDLELVPGGGGSGKGMGMGNGKSWRDGQKVWGFWVKPPLMCWLRPV
                     SRD"
     gene            complement(11407..18214)
                     /locus_tag="EPUS_05790"
     mRNA            complement(join(11407..13062,13115..13876,13924..16166,
                     16225..16418,16470..17476,17524..17815,17874..18214))
                     /locus_tag="EPUS_05790"
                     /product="hypothetical protein"
     CDS             complement(join(11407..13062,13115..13876,13924..16166,
                     16225..16418,16470..17476,17524..17815,17874..18214))
                     /NRPS_PKS="Domain: SAT (25-259). E-value: 3.9e-79. Score:
                     257.4. Matches aSDomain: nrpspksdomains_EPUS_05790_SAT.1"
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (393-826). E-value:
                     5e-146. Score: 478.7. Matches aSDomain:
                     nrpspksdomains_EPUS_05790_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (927-1224). E-value: 3.9e-84.
                     Score: 274.4. Matches aSDomain:
                     nrpspksdomains_EPUS_05790_PKS_AT.1"
                     /NRPS_PKS="Domain: PT (1313-1628). E-value: 2.1e-120.
                     Score: 393.7. Matches aSDomain:
                     nrpspksdomains_EPUS_05790_PT.1"
                     /NRPS_PKS="Domain: ACP (1694-1762). E-value: 7.9e-18.
                     Score: 56.4. Matches aSDomain:
                     nrpspksdomains_EPUS_05790_ACP.1"
                     /NRPS_PKS="Domain: ACP (1809-1871). E-value: 1.8e-14.
                     Score: 45.7. Matches aSDomain:
                     nrpspksdomains_EPUS_05790_ACP.2"
                     /NRPS_PKS="Domain: Thioesterase (1921-2069). E-value:
                     5.1e-31. Score: 100.7. Matches aSDomain:
                     nrpspksdomains_EPUS_05790_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     itr_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093:Beta-ketoacyl synthase (Score: 64.2; E-value:
                     1.5e-19)"
                     /gene_kind="biosynthetic"
                     /locus_tag="EPUS_05790"
                     /product="hypothetical protein"
                     /protein_id="ERF77221.1"
                     /sec_met_domain="itr_KS (E-value: 2.7e-161, bitscore:
                     526.3, seeds: 96, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 6.3e-85, bitscore: 274.4,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.5e-16, bitscore:
                     50.1, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDDSVQPNPSMPPILVGSTQASCQLFLFGDLTTSFEQDLRRLLHV
                     KDNATLHSFFEKVSAAFRTEFGKLPARQQALLPRFTTITDLLANLGETEGKPALSFALH
                     CLCEIGQFIRYFGEGSRPYPSDANTYLVALCTGSFAAAAISTSRTLSELIPAGIEAVLA
                     AFRTGLCSLELRNDIERPSSRIPRSWSAIVSASEAQAAELLQSFNSKNTLSGSSRLFLS
                     AVSPNSITISGPPSILHNFLASVSLNSYCLPNESPFHAPSLFGSYEVNEIISYFPDELL
                     GSYKPRIPLLSAASGKPIVAEDFKTLLHTVVSDTLCEQVRWDNILRSLVEDVFQQKSFK
                     ECTISPVLSNAAHLLSSAITRATKINVTTTNLLNLGVSDSQPARPTGKFEQSKIAITGF
                     SGRFPEAASNEEFWELLSAGRDVHRTIPEDRFNWKTHFDAAGKVKNTSRVQYGCFINEP
                     GLFDARFFNMSPRESQNTDPAQRLAITTTYEAIEMAGLVPNRTPSTQQDRIGVFFGVTS
                     DDWREVNSGQNIDTYFIPGGNRAFVPGRISYFFRFSGPSLSIDTACSSSFAAIQTACNY
                     LWRGECDTAVAGGTNVLTNPDNFAGLDRGHFLSTTGNCNAFDDGASGYCRADAVGSVIL
                     KRLEDAQADNDPIFGVIDGAFTNHCGQTESITRPHEGDQASVFNRIMRNSNVNPLDVSY
                     IEMHGTGTQAGDATEMNSVLSVFVPGRERMPHHPLYLGSAKANVGHAEAASGVSALIKV
                     LMMMKNNQIPPHCGIKTKINRNYPLDLKERNVNIALKTVPWHRTDCVGGKRTCFLNNFS
                     AAGGNTAVLLEDAPLPQSENTAIETRSVHPVIVTAKSVQSLKQNIESLITFLEKNPSTS
                     LPSLSYTTTARRIHHNYRTICSGSDIESIRDALRQKASSSDIKPIPNVTKLPKVAFVFT
                     GQGCLYAGVGKQLFETVSHFRADILRFDNIAQRQGFPSFLPVVDGSVANVGELEPVVSH
                     LAVTCVQMALSRLWISWGVVPSLTTGHSLGEYAALYAAGVVTASDAIHLVGTRAQLLSK
                     HCNKGTHTMLAIKASLDSIKPRLSASVCEVACFNQPASNVISGPSEEISRLMREYQSDG
                     FECIELDIPFAFHSAQVEPILELFERAANGVQFHAPSIPYMSPLLGRIISDGDVLGPSY
                     LARACRNAVNFQGALQAAKASSVVNEKSVWLEIGSHPACSGMIKGTLGTHALTIPSLKK
                     ATDTWKVLASGLESLYLSGIEIDWNEYHRDFESSHKVLELPRYCWDLKNYWIQYRNDFC
                     LTKGDDPPPQKEIGAAPAVEQKPVPLYISPSVQRILEEHNAADVSTLLAESDIHDPRLA
                     PIFQGHNVNGTALCPSSLYADIALTVVDYMLKTNDMQNDTTGLDVGDVKVDKSLIADSN
                     AVTQLLRISASANWSTKVVSLALYSINAQGRKLADHAKCQVRITEKQSWFQEWKRSSYL
                     IKSRVTSLYKGVDGGDSHQIKRGMVYKLFSSIVDYDARYQAMQEVVLDSNELEATAQVS
                     FQVDDEGFNFNPCWIDGLGHIAGFIMNGNDNVHSKDQVFINHGWDTMRCATKFRKGKTY
                     RSYNKMQLVSGSLYAGDTYILEDDNVVAVIEGVKFAGIPRQVLNQVLPPKSGAAGPAVT
                     KSRSSTQSKPVPMATANPLPKSTRTATATPLPKQAISPPNSNTKHTKASPTNSIVPLVL
                     AIIAEEAGLDAAELGPSSEFADYGIDSLLSLTITGRIQEELGLDLPSSLFVDQPTVKEF
                     TVFLDSSNNRPLLSSPSGNSTPVSNPEQETLSEATPEDYETDATSVTDGQSVMEIIRAT
                     IAAETGVSLEDLTPSTSFSELGVDSLLALTIMGKLGEVLETDLPQTLLADNDNLSEIEK
                     ALSLKLKGPDLNRNPVATSPRADPFDPEMPPHATSVKLQGNPKNATKTIFLFPDGSGSA
                     TSYASIPKLSPEIVVYGLNCPWMKTPQDMKCSLEHLTSKYIIEIRRRQPKGPYYFGGWS
                     AGGICAFEAAQQLASQGEETRRLILIDSPNPVGLENPPQRMYDFFESLDFFGMNGKAAP
                     SWLRPHFNAFISTLDHYKVKPFSGPRLETHLIYARDGICKHPSDPRPEIRPDDPREMLW
                     LLNNRTDFSGRGWDDLVGKENLKIQVLDEVNHFSMVAPGPKIQELGAFIARAME"
     aSDomain        complement(11695..12138)
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EPUS_05790_Thioesterase.1"
                     /evalue="5.10E-31"
                     /label="EPUS_05790_Thioesterase.1"
                     /locus_tag="EPUS_05790"
                     /protein_end="2069"
                     /protein_start="1921"
                     /score="100.7"
                     /tool="antismash"
                     /translation="TIFLFPDGSGSATSYASIPKLSPEIVVYGLNCPWMKTPQDMKCSL
                     EHLTSKYIIEIRRRQPKGPYYFGGWSAGGICAFEAAQQLASQGEETRRLILIDSPNPVG
                     LENPPQRMYDFFESLDFFGMNGKAAPSWLRPHFNAFISTLDHYK"
     aSModule        complement(11695..12474)
                     /domains="nrpspksdomains_EPUS_05790_ACP.2"
                     /domains="nrpspksdomains_EPUS_05790_Thioesterase.1"
                     /final_module
                     /incomplete
                     /locus_tags="EPUS_05790"
                     /tool="antismash"
                     /type="unknown"
     CDS_motif       complement(11887..11961)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EPUS_05790_0007"
                     /evalue="5.60E-13"
                     /label="NRPS-te1"
                     /locus_tag="EPUS_05790"
                     /protein_end="2005"
                     /protein_start="1980"
                     /score="41.2"
                     /tool="antismash"
                     /translation="QPKGPYYFGGWSAGGICAFEAAQQL"
     aSDomain        complement(12289..12474)
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EPUS_05790_ACP.2"
                     /evalue="1.80E-14"
                     /label="EPUS_05790_ACP.2"
                     /locus_tag="EPUS_05790"
                     /protein_end="1871"
                     /protein_start="1809"
                     /score="45.7"
                     /tool="antismash"
                     /translation="EIIRATIAAETGVSLEDLTPSTSFSELGVDSLLALTIMGKLGEVL
                     ETDLPQTLLADNDNLSE"
     aSDomain        complement(12616..12819)
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EPUS_05790_ACP.1"
                     /evalue="7.90E-18"
                     /label="EPUS_05790_ACP.1"
                     /locus_tag="EPUS_05790"
                     /protein_end="1762"
                     /protein_start="1694"
                     /score="56.4"
                     /tool="antismash"
                     /translation="LVLAIIAEEAGLDAAELGPSSEFADYGIDSLLSLTITGRIQEELG
                     LDLPSSLFVDQPTVKEFTVFLDS"
     aSModule        complement(12616..16930)
                     /complete
                     /domains="nrpspksdomains_EPUS_05790_PKS_KS.1"
                     /domains="nrpspksdomains_EPUS_05790_PKS_AT.1"
                     /domains="nrpspksdomains_EPUS_05790_PT.1"
                     /domains="nrpspksdomains_EPUS_05790_ACP.1"
                     /iterative
                     /locus_tags="EPUS_05790"
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(join(13018..13062,13115..13876,13924..14061))
                     /aSDomain="PT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EPUS_05790_PT.1"
                     /evalue="2.10E-120"
                     /label="EPUS_05790_PT.1"
                     /locus_tag="EPUS_05790"
                     /protein_end="1628"
                     /protein_start="1313"
                     /score="393.7"
                     /tool="antismash"
                     /translation="PSVQRILEEHNAADVSTLLAESDIHDPRLAPIFQGHNVNGTALCP
                     SSLYADIALTVVDYMLKTNDMQNDTTGLDVGDVKVDKSLIADSNAVTQLLRISASANWS
                     TKVVSLALYSINAQGRKLADHAKCQVRITEKQSWFQEWKRSSYLIKSRVTSLYKGVDGG
                     DSHQIKRGMVYKLFSSIVDYDARYQAMQEVVLDSNELEATAQVSFQVDDEGFNFNPCWI
                     DGLGHIAGFIMNGNDNVHSKDQVFINHGWDTMRCATKFRKGKTYRSYNKMQLVSGSLYA
                     GDTYILEDDNVVAVIEGVKFAGIPRQVLNQVLPP"
     CDS_motif       complement(join(13865..13876,13924..13941))
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EPUS_05790_0006"
                     /evalue="2.80E+01"
                     /label="PKSI-KS_m3"
                     /locus_tag="EPUS_05790"
                     /protein_end="1363"
                     /protein_start="1353"
                     /score="-1.4"
                     /tool="antismash"
                     /translation="TALCPSSLYA"
     aSDomain        complement(14329..15219)
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EPUS_05790_PKS_AT.1"
                     /evalue="3.90E-84"
                     /label="EPUS_05790_PKS_AT.1"
                     /locus_tag="EPUS_05790"
                     /protein_end="1224"
                     /protein_start="927"
                     /score="274.4"
                     /tool="antismash"
                     /translation="VFTGQGCLYAGVGKQLFETVSHFRADILRFDNIAQRQGFPSFLPV
                     VDGSVANVGELEPVVSHLAVTCVQMALSRLWISWGVVPSLTTGHSLGEYAALYAAGVVT
                     ASDAIHLVGTRAQLLSKHCNKGTHTMLAIKASLDSIKPRLSASVCEVACFNQPASNVIS
                     GPSEEISRLMREYQSDGFECIELDIPFAFHSAQVEPILELFERAANGVQFHAPSIPYMS
                     PLLGRIISDGDVLGPSYLARACRNAVNFQGALQAAKASSVVNEKSVWLEIGSHPACSGM
                     IKGTLGTHALTIPSLK"
     CDS_motif       complement(14863..14982)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EPUS_05790_0005"
                     /evalue="4.20E-14"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="EPUS_05790"
                     /protein_end="1046"
                     /protein_start="1006"
                     /score="44.5"
                     /tool="antismash"
                     /translation="GVVPSLTTGHSLGEYAALYAAGVVTASDAIHLVGTRAQLL"
     CDS_motif       complement(15169..15216)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EPUS_05790_0004"
                     /evalue="4.90E-03"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="EPUS_05790"
                     /protein_end="944"
                     /protein_start="928"
                     /score="10.1"
                     /tool="antismash"
                     /translation="FTGQGCLYAGVGKQLF"
     aSDomain        complement(join(15523..16166,16225..16418,16470..16930))
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EPUS_05790_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="5.00E-146"
                     /label="EPUS_05790_PKS_KS.1"
                     /locus_tag="EPUS_05790"
                     /protein_end="826"
                     /protein_start="393"
                     /score="478.7"
                     /tool="antismash"
                     /translation="IAITGFSGRFPEAASNEEFWELLSAGRDVHRTIPEDRFNWKTHFD
                     AAGKVKNTSRVQYGCFINEPGLFDARFFNMSPRESQNTDPAQRLAITTTYEAIEMAGLV
                     PNRTPSTQQDRIGVFFGVTSDDWREVNSGQNIDTYFIPGGNRAFVPGRISYFFRFSGPS
                     LSIDTACSSSFAAIQTACNYLWRGECDTAVAGGTNVLTNPDNFAGLDRGHFLSTTGNCN
                     AFDDGASGYCRADAVGSVILKRLEDAQADNDPIFGVIDGAFTNHCGQTESITRPHEGDQ
                     ASVFNRIMRNSNVNPLDVSYIEMHGTGTQAGDATEMNSVLSVFVPGRERMPHHPLYLGS
                     AKANVGHAEAASGVSALIKVLMMMKNNQIPPHCGIKTKINRNYPLDLKERNVNIALKTV
                     PWHRTDCVGGKRTCFLNNFSAAGGNTAVLLEDAP"
     CDS_motif       complement(15763..15807)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EPUS_05790_0003"
                     /evalue="9.40E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="EPUS_05790"
                     /protein_end="746"
                     /protein_start="731"
                     /score="9.0"
                     /tool="antismash"
                     /translation="GSAKANVGHAEAASG"
     CDS_motif       complement(15874..15921)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EPUS_05790_0002"
                     /evalue="8.50E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="EPUS_05790"
                     /protein_end="709"
                     /protein_start="693"
                     /score="11.7"
                     /tool="antismash"
                     /translation="YIEMHGTGTQAGDATE"
     CDS_motif       complement(16352..16399)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EPUS_05790_0001"
                     /evalue="1.10E-05"
                     /label="PKSI-KS_m3"
                     /locus_tag="EPUS_05790"
                     /protein_end="569"
                     /protein_start="553"
                     /score="17.5"
                     /tool="antismash"
                     /translation="GPSLSIDTACSSSFAA"
     aSDomain        complement(join(17333..17476,17524..17815,17874..18139))
                     /aSDomain="SAT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EPUS_05790_SAT.1"
                     /evalue="3.90E-79"
                     /label="EPUS_05790_SAT.1"
                     /locus_tag="EPUS_05790"
                     /protein_end="259"
                     /protein_start="25"
                     /score="257.4"
                     /tool="antismash"
                     /translation="FLFGDLTTSFEQDLRRLLHVKDNATLHSFFEKVSAAFRTEFGKLP
                     ARQQALLPRFTTITDLLANLGETEGKPALSFALHCLCEIGQFIRYFGEGSRPYPSDANT
                     YLVALCTGSFAAAAISTSRTLSELIPAGIEAVLAAFRTGLCSLELRNDIERPSSRIPRS
                     WSAIVSASEAQAAELLQSFNSKNTLSGSSRLFLSAVSPNSITISGPPSILHNFLASVSL
                     NSYCLPNESPFH"
     gene            complement(20093..20594)
                     /locus_tag="EPUS_05791"
     mRNA            complement(join(20093..20377,20448..20594))
                     /locus_tag="EPUS_05791"
                     /product="hypothetical protein"
     CDS             complement(join(20093..20377,20448..20594))
                     /codon_start=1
                     /locus_tag="EPUS_05791"
                     /product="hypothetical protein"
                     /protein_id="ERF77222.1"
                     /transl_table=11
                     /translation="MSKKLFALTICGYRKSGMDEDEYHRYLSDNHAPLLKDLLIKNKII
                     DYTMQHNTSETKKMMGQIFGSLHAGNVAECDCFVQIVFRDVQDFINVKEDPHYKKMVVP
                     DHENFADGKRTTIVTGWFESHIPSRHGGAIENGVSINGH"
     gene            complement(21844..23211)
                     /locus_tag="EPUS_05792"
     mRNA            complement(join(21844..22175,22248..22532,22589..22886,
                     22981..23211))
                     /locus_tag="EPUS_05792"
                     /product="hypothetical protein"
     CDS             complement(join(21844..22175,22248..22532,22589..22886,
                     22981..23211))
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087:hypothetical
                     protein (Score: 118.8; E-value: 5.6e-36)"
                     /gene_kind="other"
                     /locus_tag="EPUS_05792"
                     /product="hypothetical protein"
                     /protein_id="ERF77223.1"
                     /transl_table=11
                     /translation="MAIHWSLDHLEKLLPKRLFAKLSEISCNPNVPIEAGGNYPIINAE
                     TGDLLAGVPYARGFRVPRSKMRALCAEGIDVQYGKNLTDLAFSEKGDLVFASFSDGTIA
                     QGSVLLGADGPRSKVREFAMSGAEAAQVSKFPICHHNMTVCYRDVDKAKYLRQRFPTSY
                     LALSQKSHHAFQSISSMPDGQDHPETWLFHLAMAWLGDPEHSLSYEERLAIIKERAQGM
                     GEPARSAFTWIPEDTLVHKADISYWITQPWDNRGGRVTLVGDAAHPMPPYRGQGLNHCI
                     CDSSHLLDGLELVRANKATIKDAITAYDEELVPRGRDEVKCSLENGLMLHDWQKVKESP
                     VFRNGFRPMTGHDGKEALSEHAQAQMKRDEEEQRDIPVAAT"
     gene            24952..26270
                     /locus_tag="EPUS_05793"
     mRNA            join(24952..25717,25957..26270)
                     /locus_tag="EPUS_05793"
                     /product="hypothetical protein"
     CDS             join(24952..25717,25957..26270)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="EPUS_05793"
                     /product="hypothetical protein"
                     /protein_id="ERF77224.1"
                     /sec_met_domain="Fe-ADH (E-value: 7.7e-37, bitscore: 116.1,
                     seeds: 218, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTFVESSISPLFGLWQPLPHLKHLYYGSSCVQKHLFATLPSHDS
                     KVFIVTGNSIATKTPLLQQVETLLGDHHAGTFTKIRQHAPMADIDQATEIIAKNPLVDT
                     ILSLGGGSPIDSAKTISFRMHERNGKFLTHLTIPTTLSAAECTIGGGYTKADGVKTSVM
                     TPEIGVTAVFYDPGYAKYTPLKLWLSTGMRAMDHAVESQYQPYASEMPWRAMSSWAVST
                     FFECLPIAKASHPSDEDVITRLLLAAFASLGFRDGETSCLTLGPVVQLKARAKQEDAKQ
                     IARLLPWIGGTSSGDDLKDALEVGCKISALVESLGLHQSLTERGIGRDQIPIVVERATG
                     GLKEGSLYDIVTLLVEGLY"
     gene            complement(27838..29342)
                     /locus_tag="EPUS_05794"
     mRNA            complement(join(27838..28463,28536..28621,28681..28773,
                     28837..29342))
                     /locus_tag="EPUS_05794"
                     /product="hypothetical protein"
     CDS             complement(join(27838..28463,28536..28621,28681..28773,
                     28837..29342))
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:O-methyltransferase (Score: 165.4; E-value:
                     3.3e-50)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="EPUS_05794"
                     /product="hypothetical protein"
                     /protein_id="ERF77225.1"
                     /transl_table=11
                     /translation="MAREANTATMLTLAGEIFGQTYQLEKFMKEKSIKEPSLAVGAYTE
                     LWSSHTTEIATAQTSILDLTQKLTKLLYGPHGFLHEYVSSNWEYGALYTVLEFDILEKI
                     PLDGEVHVSELAMLSGLPENKLLRILRLVACEQILEETSEQVFRHTVISEELVRNKKMK
                     AWVGFQLFETRVASAHLADSLKHRNDFQTGSSAFKHAWGASMYDWHKAHPEKFARFNLA
                     MQGVTQSLDPGNGLFCDWFNSNKRNKHRNLVVYIGARDGHVYQYLAEQYPDISVEVQDN
                     SEQLLTQGQKSLPPDLQPRITYTKREIFTPQPAPSSPDNQTLAFILRNVLWNLSDSDAI
                     TLLRTFIPVLEASPETVILVNDMLSPARGEFDAQTEKAYRRRDITVMTMHNAKQRTEGD
                     WRQLFEAVSPHFVVRGWTAFTSHAYRGLWEIKWVLAN"
     gene            complement(30329..31462)
                     /locus_tag="EPUS_05795"
     mRNA            complement(join(30329..30971,31086..31462))
                     /locus_tag="EPUS_05795"
                     /product="hypothetical protein"
     CDS             complement(join(30329..30971,31086..31462))
                     /NRPS_PKS="Domain: PKS_ER (20-242). E-value: 1.3e-34.
                     Score: 111.6. Matches aSDomain:
                     nrpspksdomains_EPUS_05795_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028:crotonyl-CoA reductase / alcohol dehydrogenase
                     (Score: 170.5; E-value: 8.5e-52)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="EPUS_05795"
                     /product="hypothetical protein"
                     /protein_id="ERF77226.1"
                     /sec_met_domain="ADH_N (E-value: 3e-10, bitscore: 29.3,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 2e-11, bitscore:
                     33.3, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQLTTTQYQAIGKGGPFAVVSVPKPTPGHNEVSIRMEAVALNPLD
                     WKKLYFGAMVESWPTVLGIDGAGIVEAVGEGITRYKTGDEVFSLFGHETKAASFQEVAV
                     VPEHYVAKKPGNISFEEAASLPICYCTAGSAIYYGLQIPLPFLPDGTTSGPQPKSILVL
                     GGSSGVGASAIQILRLALPSATILTTSSSKHHVYLESLGATQAFDQKSPSLIEDIKSAT
                     PEGKGVEMILDAVASSASQKDIFDTLSADGPKEYSEVFTGTPTLVPDGVKRHVVYGRKL
                     FETPGGQNVMTALADLVRKGDYKIPIQVKNVGSGFEAIGPGLEELKAGVSATKLVVTI"
     aSDomain        complement(join(30623..30971,31086..31402))
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EPUS_05795_PKS_ER.1"
                     /evalue="1.30E-34"
                     /label="EPUS_05795_PKS_ER.1"
                     /locus_tag="EPUS_05795"
                     /protein_end="242"
                     /protein_start="20"
                     /score="111.6"
                     /tool="antismash"
                     /translation="SVPKPTPGHNEVSIRMEAVALNPLDWKKLYFGAMVESWPTVLGID
                     GAGIVEAVGEGITRYKTGDEVFSLFGHETKAASFQEVAVVPEHYVAKKPGNISFEEAAS
                     LPICYCTAGSAIYYGLQIPLPFLPDGTTSGPQPKSILVLGGSSGVGASAIQILRLALPS
                     ATILTTSSSKHHVYLESLGATQAFDQKSPSLIEDIKSATPEGKGVEMILDAVASSASQK
                     "
     CDS_motif       complement(30821..30874)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EPUS_05795_0002"
                     /evalue="1.30E-03"
                     /label="PKSI-ER_m5"
                     /locus_tag="EPUS_05795"
                     /protein_end="176"
                     /protein_start="158"
                     /score="11.5"
                     /tool="antismash"
                     /translation="SILVLGGSSGVGASAIQI"
     CDS_motif       complement(join(30953..30971,31086..31099))
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EPUS_05795_0001"
                     /evalue="2.40E-03"
                     /label="PKSI-ER_m4"
                     /locus_tag="EPUS_05795"
                     /protein_end="132"
                     /protein_start="121"
                     /score="11.5"
                     /tool="antismash"
                     /translation="AASLPICYCTA"
ORIGIN
        1 tcaccaagcc tgcacaccat ccttcgtaat gaccttacca acgtcaccat ccctttcacc
       61 ctccaaaaca ctcctgatga aagggcccgc caccgccgga tcaccagctc ccattttctt
      121 tgaggcctcc ggattcccac caaggcccgt agccgagaaa cctggagcaa gacaccatac
      181 tttcacaccg tcttccttca gcgtgcggtg ccattcacgc atcatcatgt tcatgccgct
      241 tttggcactg cggtatgccg caatactgaa accgcgtttc ggccaccctt taggaggaga
      301 gcggtcaatg ggtagagcaa ggttctcggt tccagcgaga gtggacgcgt tggacgtgat
      361 gaacagcagg cgcgggtcag gagtctggag caggagaggt atgaagcttg aggtcattac
      421 ttgcgccccc acggtgttga tattccatga ctggttccaa atgtcgcgct ccgtcagctt
      481 accagcggca aactgcgctt cgagctgcgc gcctgcggtt cttgtcagag aacactgtcg
      541 tcgttgctga tgcattatac acataccagc attgtttacc aaagcatcaa gctttccgaa
      601 cttagactgc acctcgttga acgcgtgttt gatagagtca tcctgctcaa tgtcgacctg
      661 aattggaaaa agcttactgc gagaggaggg gaactcctta acagcggagc tgatggcatc
      721 ctcagccttg gacagcgatc gcccaccaac gatgatgtcg taagcttgat cagagctgca
      781 gagtgacctc acaatctgaa aaccaatgcc agtgttggca cccgtgatca agacgactct
      841 tggagccatt gttgcgagcg gttgaggtcg atctacacaa gactcgagga gagcttacga
      901 tttctgtctt gaaggattcg gagttcgtat agcccttgac atcggaaacc caaacacccc
      961 actcggcccg cccacgtgat tttatcccac cagtgaccgt cgccatccgg ccctcaggct
     1021 ttcgaatctg tgggtctttg caaaccaggg ccggccattg taccccgact cgagtcgctg
     1081 ctgtacgtag tcgggcatca aaagtcttca atatacacta actaggaaga agaacggcta
     1141 gctgttcttg tggtagcttt gtgctactct ctggggacga ttgcgggccg gctgaagggg
     1201 ccgaatgcct aatacgccca acagcctaga cgaagcctct atagacaatc caggatatca
     1261 gggtctgtca agaggcactt agaggggccc tctctacgga gtcatgcacc agaagtagtc
     1321 aaactacgct aatactaata aggtaagagc tagaaggtaa gtgtaagcta caccctctag
     1381 cctaaaatat atagcggata atgtataagc gtgctgagat gggcctccac actaggggca
     1441 ctatggtata agtgggcaat cacttaaagg gaagcctaaa gaacactgat caaggggctt
     1501 ctctaggctt tctttagatc aaagtatctg tacaactaag cattctctta cgctaatgag
     1561 caatcgctat ccttggtaga gtcttaatgt cagcgtagtt ttgactactt ttggtgcacg
     1621 actccgtatt gtgcgtggat aactacgtac acagtgctaa gctcagctag agagtgctag
     1681 tgggcgctct agtcatagcg catattgtta acttttgatg cacgactctg tatcctttcg
     1741 tgctcgacaa tgggtttcaa gaactgatcc cggagtgaac tataggactg tgaccctctg
     1801 catggagtcg ataacgatgg cgatcttact tcaggttaac actcacttcc tgtctcatcg
     1861 cactggttcg cgatcacaga tctcactgcc tacggagcat acagaatcgt gacagatcct
     1921 ctccgcagag tctccagcct atagctcgct cgctcgctcg cttcacacgc ctttgggacc
     1981 tccaacaccc ctgacgatat gcctccattt ccgaagcaaa gcggcgaaat aggtatggca
     2041 atcatggtag tgttactcgg gaaacaggct cgtacttgac ggtgaacacg ttaaaatcag
     2101 acaaaagaaa cggtcacaga atgcacaaga gaacttcttt tcgagaccgc tgatcattat
     2161 gtggctataa tgccgcggac aggatgtgtt ccgttctttc actcagccgt tctctcttcc
     2221 agaagcggca cggttcgcag ttctctcagc aacgactggc ccagtgtcga gtgtcctctc
     2281 tctacctccc gtcccagctt atcaatttgg gtggatcatt ggctcgtaga ttatcgtcaa
     2341 gacaacagta tattcctatg agcgaaccaa gtcttttcta ttgtatgagc tgagcaccgg
     2401 caatatcctt aggaggggtg atatctataa tacagcggta tgtatgtcct cttgcgccgc
     2461 aacatcaaac gacatcatag ggcttgcggc caggagttcg gaaagaagcc tcgagttggg
     2521 tgattcatcc ataacagcat tcggcccact taaacgcact cgcttcctgc ccgacggtga
     2581 cattatactc tgcggctgct cgaaatgtgg agaaaagaat tccagttcca ttggagtaag
     2641 taagccaggt gaagggcatg tactgaccga ggtggtcgct gcggtagagt tattcttgga
     2701 ggagaagccc tccaatggca tgggaggtgc tgggtaagac gatgcagtcg acaggtctgt
     2761 gaagtcggaa agtccttgtt ggccagcaaa gaagttttga gtgctgggtg gagtatgagc
     2821 ggtgcttgcc tgatgtagca tggttggtaa tggttgaagt tgttggtcat ttttaacgag
     2881 gtttaccact tgcaaaagtc ttccgaaagc gtgtccaact ttgcgcgtgt ggttgttcgc
     2941 ttgacttccc ccttcaagtt ctctgtagca tgcgcatact ttctgcaata gattcatgtc
     3001 ttcgtctgct tgtgattcat cgtctgttga tattggctgt ataagattcc ttgctagtaa
     3061 gaaaaatccg tgtgccgaga aagtatctgg cagacggtgt gaacgtaacg atataggttg
     3121 atttgcattt tcctctgtgc tgccagagca agcgtcgttg ctggaggtct tgtctttgct
     3181 cgatcgacga ctggtagatt tgttgagacc tttcagcgat gggcttttcg agattgagag
     3241 accgtcaggt cgctgaaaca tagactgatc acacttaccg taggagatga gcagcaaaaa
     3301 acaactggtt cttgcgtcat tcaatacccg gcgtacatga acgggctcaa gactgccatg
     3361 caggacactg atgcgggccg ctaaaaactc gagttgcaag tcgacattgc gagggttagt
     3421 attaactgag gtgaaaatat catgggtatc ggcccaacgc tcaagacttt gctcgatgcg
     3481 taacagtaaa gtcttatgcc taatcgagca tcgcctttgt gattccgctg gatgaaataa
     3541 tcggtagatt tcctcttgca acttggcaag ttgtacccga gaggcgagtt ttggatcagc
     3601 aatggcactc tggtcgagct gagaggagag actgcaatcg gaacctggaa gccagcagaa
     3661 agatcctcgc gaaatcgtga agctcttatc tcgaaggtat aatgatttga agactttgaa
     3721 gcgctcttgc tgttcctctg gactagcgtt atctgatgcc atcggcgttt gatggagacc
     3781 tagggttctg gctagtacac aagcttgcgc aaaaatcgag tccgcaaaac ctggcggata
     3841 gtactgttga gcagcgagac tcttgcagaa acagttagta atcatggcag cgtagtatgc
     3901 aatttaaatg atcattcaga agcactcacc aaaagtgcca aagcctgcac attgatcaac
     3961 tttggcgcca tcaggacgcg aggattgttt agagctgtgc gaactgttga gaggaatggt
     4021 aggacgaact gtgattcgac tattggatca ctgttttgaa tttgcacttc tgacccaagg
     4081 accagcagga taattgtgtt gaagcagatc gcccaagctt tgtcggccgg cgtaaagggt
     4141 tggctataga ttcgttccac gttagaccag aaggatgatt gcacaaatat atctgtcgcg
     4201 tagtctgctt gctgaaagca ttgattttgt atcatgaaga ggaactgctt gggtggaagt
     4261 cggatggggg tgtgattcgg ttgaagatca aaagactctt caataccggc ttcgagacac
     4321 atacggacga gcacgtcctt gactgcttca ttctttgcga agtcttcctg tttattggat
     4381 tttggtaact ggtccttgcc cggagccggg ccgggtgtcc actgctccga caagatggta
     4441 tcgctgaagg cgttacaaag agctaacaaa gtgcaaggac catgatgacg atctatagga
     4501 tcattatgac ggcacgcccc ctgatcatgc gtcggcaacg aacaggatgt cacgtcggca
     4561 agagagtcct tgattgataa agtggctgac gactcttcgg ttgttgagtt atccatgaac
     4621 ggcctttgat gaacaccggc cttgagtaat gtcatcaagc gtgagagctc gccctcgatg
     4681 ttactcaggc gatcctcaag accgccaatg ttgttgcatc tgcgaaggtc agtgtgttag
     4741 gccgataata tgtttgacca agcaatgtgc aatgaagtgg ctcgaggagt gagatccaac
     4801 ttacaatagc ttgatatgat tgaccctctt gccaggggtt gagtattcgc actccactcc
     4861 atcacgcctg caatgtgcac attgtggtct ctcacgcccg caccgaattt ttctttcgcg
     4921 gcaatgagta caagctatgt catgagtaga ccatgactgc gtctatttca gggagtgtca
     4981 gctagggcga tgtggtgaaa catgtgaaaa tatgctgacg catgcgaggg tcgaggtaga
     5041 atgcttcatt gtttggatgg gcataccggt ttctctgatg gcgccatagt gtcggaaggg
     5101 aagcgcgtgg accaagtgct ggagcgacaa tatagtcatt caaacgtaac cgtgtcagac
     5161 gttagtcttt tccacttcaa ggcaatcaag gcaatcagaa gagtcaagtt gatcgtataa
     5221 gaaaagactg tttgcgtatt gtcttatcat ggaacaagcg tgaggtcgat caatggtttg
     5281 gaaaatcggc tggtcctgtc aagtccttta tcgaaactca aagcagggca gtccatacgc
     5341 aacttctcca gagtacattg catctagtaa gcatgagcct cgaccttacc atcccagaaa
     5401 tcctagatgc cggactgatt gcaaaccaac atcgtactcc tcctgaaacg gtgtttcgct
     5461 ctgtaatacg tggtaaatcc gacattgtgg agcagtatca gctcaatgca tcaattgggg
     5521 tgtgtatgac taggaatcta cgtactagta gtaaaataca aagtttggat ggaataactc
     5581 cgcaggcgcc aaggccccat gacgtggcca tggtactact agtactaact actatgcgag
     5641 gttgtacacg ggggggtact ttacccgcag ccggaccctg atagcgcacg ccactaatac
     5701 cactagtaat aacagtacaa taagtcttcc tgagtgctca tgattgatca taataatttg
     5761 tactacagtt gcatacaaat tgttgagatt aatcctggta aagtaagaat cttaattatt
     5821 taatatacat tctctcaaaa atgattgcac atgattgttc atgattactt ccaataattt
     5881 gtactatagt tgcatacaaa ttgttgagat taatcctaat aaagtaggaa tcttaattat
     5941 ttaatacaca ttctgtcaaa aatgattgct catgattgct catgattgct catgattact
     6001 cacaataatt tatactacat ttacatacaa attgttgtga ttaatcatga tcaatcagga
     6061 agacttattg tataattaga ataccaagct aatacagagt taattcccac taatgcacac
     6121 taataagggt ccggctgcgg gtaaagtaca cctccgtgtg gtacctccta gccatggccc
     6181 aatgggtgga gcccttacca gggcccactt gtagagggtt gcccccctac aagcccgcgc
     6241 gcagcgcgtg gctgccaccg taacgctcat accaccgtaa cgcttaactt tcgctcatgc
     6301 tacattaatg cttataactc tatgaattct tgatggatta agctgaaatt ttaagtatag
     6361 atacttgaaa ttatattaaa tataatagag gtctaaaaat ctttatattc taagtattaa
     6421 agtagtaaaa gcttattttc aagaagctta atttatagaa atacagaact aataaagata
     6481 taacaaaaat aaaaaaagta tgaatttatt gtataataaa aaattttgga aaaataataa
     6541 gatattatta atttatttaa aaataaagtt attaaattgc tggaggtctt gtcnnnnnnn
     6601 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     6661 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     6721 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     6781 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     6841 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     6901 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     6961 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7021 nntatataat atttatagtt taaacttcat ttaaattcat caagaattca tagagttata
     7081 agcataaata tcagttaagc aaaagttgag cgttacagtg gtatgagcgt tgcggtggca
     7141 gccacacgct gcgcgcgggc ttgtaggggg tgcacccccc tgcgagtggg ggccccaggg
     7201 gctccaccca ttgggccacg gctactatgc gaggcctccg cacgaaagga actacaccat
     7261 aaagagcagg cgctttggtg ttgcgtacag tggccgaagc tagggcccag agatcttgag
     7321 ttttgtttgc gttgtttgag ttgtttaagt tgtttaagta aactgaaaca gtggtaacag
     7381 ctgtatatat ctaactttta taacactctt acaaatgggt agtgctataa tagcgggact
     7441 gagagtccta caagagcgag gctttgacat atctcaagca ttgttcgggt ttcacaaagc
     7501 ttgacaggca caggtctgcg gaaagcggtg agccatgcat gctagcatac agttatccat
     7561 catccttatc ggagaatgta aaataaaaat tattaggtta ggtacccttc gtattcatgt
     7621 ccttcaccga gtcattctgt gcctccacac ctctttcatc cttcggggcc aaggttgatt
     7681 aggaatatag ggagaaaaac gcgtatagca ttgtatcccc cgtgtgtcaa tgattggtga
     7741 gcatcctaat taggactaag gggataagtc agcggtgagg ctggtgtcta tcctgtagtg
     7801 tcgcataagt gcacatgccg tagtgaccat ccctccatca gtgtactcag tacaggttct
     7861 tcagactatc acagggtcaa tgcttatgca agttgacacg tcagaaaagg acattggaag
     7921 acgtgacgtg tcttgataag atcgcagtga gataagttcc tgattcagtg taacagtcta
     7981 atcacacatc tcactttcat tggcaacagc cttaaagccg atatcaccgt ttgtgtcaat
     8041 tttaagccac caactttttg tccagtgtca tcctacaaat gctcatctat gatgtcagga
     8101 gggcagggtt atccctgtgt cactgaatgg gcaacatttc cctgtagata tagtgttcct
     8161 atgagcctac atgaatcaga tgcctggcat tgctgtgata gtgctaattc gaaagtaata
     8221 ggttcatgtt tcaagaaaga ttctccacta aatgactcgt gagaagtcta cctactgaaa
     8281 aaagacctct cttgctgctc agactagctt cactcaacta gagctaccga acgtgtcgtc
     8341 tggtttccat ctccttctca atttccttct ccaagcgaca atccatgcct cagtcaatct
     8401 ctactcacag gcctcagcca acacatcaat ggtggcttga cccaaaaacc ccagaccttc
     8461 tgtccatccc tccaactctt gccatttccc attcccattc ccttcccgct ccctccccca
     8521 cccggaacca actctaaatc aaacctccac agcagcttcg ccattatcag cctcatctcc
     8581 gctcgtgcta gattctttcc caaacaattc cgtggaccga atgagaacgg ctgcaccgcc
     8641 gccctgttgt ccttgtcaaa cggcggaaca tctttgcatt ccggaagcca gcgctcgggg
     8701 agaaactcgt ctgggcggtg gaaattagcc gggtggcgga agcaagagaa gtggtggaca
     8761 ccgacagtgg tgccggtggg tacatggatg ccatcaatgg tctcgcctgg ggcgggcacg
     8821 acacggggga gggtgccggc gacgggcggg tagagacgga gagattcgga aatgacggct
     8881 tcgaggtatt tgaggtcgtt ggtgctggcg attgtgatct cttcttcgga cgtgaaagag
     8941 gtgcgaattt cgtggatgag ttctgagtag gcggatgagc gggtgaggat gtggtatgtt
     9001 attccggaaa gagcagtcgc acttgattct gagccggcga tgttgaagga aaatgaattt
     9061 acatggatct ctgccctgct catgcctttc tcgtcgttgg cggcgaggat atagtagagg
     9121 aagtcttttc ggtcagtgtc ccgttggatt cgtcgctcca cggtgtcgat tgcgcgtttc
     9181 atgttctgag cgcgctggcc ggccacagct ttgggcaaga agaattgccg gacgcccgcc
     9241 acgccgaagt agattagcat ttgggtgaag gtgagctctt ttgctatcct ctccgttgcg
     9301 cggacgaagg ggacgtaatc acccttgtca aggcacccga acttttcgcc agacgacagg
     9361 tctcctatca ggtcgaaggc tacgatgcga gattagcgac aatattcgtg actgatattg
     9421 ctgcaaatac ttacttgtga aattgtacca tgcgaccatg ttcagcggtc ctgcagtata
     9481 tctcaaagat agctgttcca acagcttgct cacatatgtt tgtaaaatac cttcttgctc
     9541 cctaagtgct ttttcagaaa atgcatggga aagcagtcgt ctttggcgaa tatgcgtctg
     9601 gcggtcggcc accaggatat cttttacgca aatgtcagtt ccataacctt tttaggaggc
     9661 gtaaaaccaa gatgcatttg cctactacac ttgcgttcga caaaacgtct aagacggcca
     9721 tcctcagcag gacacttccc attatgattg aagttagaat gagaattaca cgggtttctg
     9781 tgcttaagtt tcccattcca agtaaagaaa aattcaactg actctgtgct ccagtaggag
     9841 tgtgaaggcg aaaaacagga tccttgtcca tctccacgga tctgtgtcca tatatcgtct
     9901 tccatgccgt gtctgaggtg aaggagagtt cgtaaggagc gatacggaca gtgtgaccgt
     9961 acttgacatg aagctccaat aaacgctcgt gtaggatgcc ttggtactga taccaacacc
    10021 atggtacgcg agttgcggcc cagagctttg gtccagggtg atttctgagc ggatgaagga
    10081 aaatgttata aaggatatga gcgatcgccc atagaattag ctgaaagtgg ctgtcagtat
    10141 tctataattg aaatttggaa ggcttgtcca gtacgagaac agagcaggcc gtcacagcga
    10201 ccacaggata ttcggctgcg ctatagctcc agctacctcg ccctcgaaga tctgcagcag
    10261 aatccattgg gcagtgatga cgacgtttct ttcacaacag catcagcacc atatgtattt
    10321 gggtcttttc ttgtgtggtt gtagcacgag agagatagag aaacttcaaa ccagacgacg
    10381 tctatatttt gaaagcgcca ttggtgccgg tacttagtgc actgagcagg tgacccaagc
    10441 ggcaagcatc ttcaactgca acctccaaaa caacaatatc atagcccaag caggagtatt
    10501 ttggatatga cccttgggta agcagttaat gcagcctgtc tctgtgctct gcgggacatg
    10561 acaggaactc gggagccgag tgagctatga agcagtcctt cgtgtccgcc taatgtatcc
    10621 cggcgagagc cagacggggg ttgtgcttgt tccgtcctgc ttccgtatca cggtgtctat
    10681 gtagtagctg tgtgccttcg ctcggtcgcc gttgtcgagc atggcaaggt gtagtgcacg
    10741 gtgggaggat gatatgtgct cccaatgccc tttggatgta tgtgtcagta tgcgagcttt
    10801 ctgtcatgtc agaaaggtga tgttgctgat ggagaagtga tcaatatgaa gctcagtaga
    10861 tcaaaggttg tatttcttta gaatggaggc gctctctagc aggttgaatt ttactatagg
    10921 gaaggcgagt acatttctct tggtggggtg gcttggggcc ctttgggctc aataggcaaa
    10981 gataccattc gctttcaaag cagtccccca cagttccaat ccacccttgg gtggcggggc
    11041 ctccaggcct ccttctgggt ggctctccac tccatgttga caatcatccc ttcttattag
    11101 aggtggatgt taggtgctca acgcctagaa tgatggcaca attaaccact tagcctccac
    11161 cgcctcttac cctgtcagct tttaacaaat cagcttccaa caaatcggaa ttacaatcaa
    11221 gcaaatgatt gaagcatgcc atcaagaacc tcactatcat ctaactagtg gacgtattgc
    11281 catagcgatt gtagattttt tctttcatgt gaataatgtt gatatcctaa acgaaatcta
    11341 taacttaaat gaacctctaa acaatctgcc atcctgtaat gtaaaactaa gccctcaatg
    11401 cttgcctcac tccattgcac gtgcgatgaa agcaccgagc tcttgaattt tcggaccagg
    11461 cgccaccatc gaaaaatgat tgacctcgtc caacacttgg atcttcaggt tctccttccc
    11521 aaccaagtca tcccagcccc tgccactgaa atcagtgcga ttgttgagaa gccagagcat
    11581 ctcccgagga tcatcggggc gaatctccgg tcgaggatca ctgggatgtt tgcaaattcc
    11641 atcacgagcg tagattaggt gagtctcaag ccgtggacct gaaaaaggtt tcaccttgta
    11701 atgatccagc gtgctgatga aggcattgaa atggggccgt agccagcttg gagccgcctt
    11761 gccattcatg ccgaaaaagt ccaagctttc aaagaagtcg tacatgcgct gaggcggatt
    11821 ctccaagccg actggatttg gtgaatcaat caatatcagt cgtctagtct cttcaccctg
    11881 gctggccagc tgttgcgcag cttcaaatgc gcatattcct cccgccgacc aaccaccaaa
    11941 gtaataaggg ccttttggct gccgacggcg gatctcgata atatatttgc ttgtcaggtg
    12001 ttccaaggag catttcatat cctgtggtgt cttcatccag ggacagttca agccatacac
    12061 cacgatctcg ggcgagagtt taggaattga agcgtacgag gtagctgatc cagaaccatc
    12121 tggaaagagg aatattgtct ttgtggcatt cttgggattc ccttggagct tgactgatgt
    12181 ggcgtgagga ggcatctcgg ggtcgaacgg gtccgctctt ggagaagtag ccacaggatt
    12241 tcggttgagg tctggtccct tcagcttcag gctcaatgcc ttttcgatct cggacagatt
    12301 gtcgttatcg gcaagaagtg tttgcggaag atccgtttct aagacttcac caagctttcc
    12361 catgatcgtg agcgctagca gagaatctac accaagctct gagaaactcg tcgaaggtgt
    12421 caagtcctca agagagacac cagtctctgc agcgatcgtg gcgcggatga tttccatcac
    12481 gctttggccg tctgtaactg atgttgcgtc tgtttcgtag tcttccggcg tagcttccga
    12541 aagggtttct tgctctggat ttgagactgg cgtcgagttg ccggaaggac ttgacaacaa
    12601 gggcctgttg ttgctactat caaggaacac tgtaaattcc ttcacagtag gctggtccac
    12661 aaagagtgaa gagggtagat cgagtccgag ctcttcttgt attctcccag ttatggtgag
    12721 ggacaacaat gagtcaatgc cataatcggc aaattcgctg cttggtccaa gctcggccgc
    12781 gtcgaggcca gcctcctctg caatgattgc caatactagg ggcacaatgc tattcgtcgg
    12841 tgacgctttg gtatgctttg tattggagtt tggtggtgat attgcttgtt tggggagcgg
    12901 agtagccgtg gctgtgcgag ttgattttgg aagcggattg gctgtggcca tcggcaccgg
    12961 ttttgattgc gttgaagaac gcgatttagt cactgcgggt cctgctgctc cagactttgg
    13021 aggcaatacc tggttcagga cttggcgcgg tattccagcg aactgcattt atttggtcaa
    13081 taatccccca ccgaaaaagc tagttagtac ataccttgac accttcaatg acagcaacaa
    13141 cgttgtcgtc ctcaagaata tacgtatcgc ccgcgtataa tgatccactc acaagctgca
    13201 ttttgttgta gcttcggtaa gtcttgccct tcctgaactt cgtcgcgcat cgcatggtat
    13261 cccagccatg attgataaac acctggtcct tcgagtgaac attgtcattt ccattcatga
    13321 tgaacccagc gatatgccca aggccgtcaa tccaacaagg gttgaagttg aatccttcat
    13381 catcaacctg gaatgacacc tgtgcggtag cttcgagctc gttgctatcg agtacgacct
    13441 cttgcatggc ttgatatctt gcatcatagt ccacaatgga agagaacagc ttgtagacca
    13501 tgccacgctt gatctggtgc gaatcgcctc catcgactcc tttgtaaagt gatgtgactc
    13561 tgctcttgat gagatacgag ctgcgcttcc actcttgaaa ccatgactgc ttttcagtga
    13621 tccggacctg gcatttcgcg tgatcggcta actttctgcc ctgtgcgtta atgctgtaga
    13681 gggcaagtga aacgactttg gttgaccaat ttgcggacgc cgaaatacga agtagttgtg
    13741 tcacagcgtt agaatcagct ataagcgatt tgtcgacctt cacgtcgccc acgtcaaggc
    13801 cagtagtatc attttgcata tcgtttgtct tcagcatgta atcaacgacc gtcagggcga
    13861 tgtcggcata cagagactaa aagagttagt agtggctaaa ttgctgtcag gaaagcaact
    13921 tactgaagga catagagctg taccattcac gttgtggcct tggaagatgg gagcaagtcg
    13981 cggatcgtgt atgtctgatt cggcgagaag agttgacaca tcagctgcat tgtgctcctc
    14041 aagaatacgt tgaacagagg gtgaaatata gagaggcaca ggcttctgct caacagcagg
    14101 agcagcacca atttcttttt gtggtggtgg atcgtcccct ttggtgaggc agaagtcatt
    14161 cctgtactgg atccaataat tcttcaaatc ccaacagtac cttggaagct ctagaacctt
    14221 atgcgagctc tcaaagtctc ggtgatattc attccaatcg atctcaatgc cgctgagata
    14281 aagtgattcg agcccgctgg ctagcacttt ccacgtgtct gtagcttttt taagagacgg
    14341 tattgtcaag gcatgtgtgc ccagcgttcc cttgatcatg ccagaacaag ctggatgcga
    14401 tccaatttcc aaccagactg acttctcgtt gacaacagat gaagctttcg cagcctgaag
    14461 agcaccttgg aagtttactg cattgcggca tgctcgagca aggtatgatg gtcctaacac
    14521 atcaccatct gagataatgc ggcccagcaa aggcgacatg tagggaattg aaggggcatg
    14581 gaactggacg ccgttggctg ccctctcgaa tagctccaag ataggctcaa cttgtgctga
    14641 atgaaaagcg aacggtatgt ctagctcgat acattcgaaa ccgtctgatt gatattccct
    14701 cattaagcgg ctgatttctt cgctgggtcc gctgatcaca ttgctggcag gctggttgaa
    14761 acaagcgact tcgcagacgg aggcgcttag acggggtttg atggagtcga gagatgcttt
    14821 gatggccagc atagtatgtg ttcctttatt gcaatgcttc gatagcaact gtgctctggt
    14881 accaacaagg tgaatggcgt cgctggctgt cacgacccca gccgcataga gggcggcgta
    14941 ttctcccagg ctgtggccag ttgtcaaact cggaaccaca ccccaagaga tccagaggcg
    15001 agaaagcgcc atttgcacgc atgtcactgc caaatgggaa accactggct ctagctcacc
    15061 aacattggcg acgctaccat cgaccacagg caaaaagctt gggaaacctt gccgctgagc
    15121 tatgttgtcg aaccgaagaa tatcagctct gaaatgcgag accgtctcga atagctgttt
    15181 gccaacacct gcatacagac agccttgacc tgtgaagacg aaggccacct tcggaagctt
    15241 ggttacattt ggaataggct tgatgtcgga actgctggct ttctgcctga gagcgtcccg
    15301 aatggattcg atgtctgacc ctgagcagat ggtgcggtaa ttgtggtgaa ttcgtcgtgc
    15361 cgtagtagtg tatgataatg atggaagcga ggtgctcggg ttcttctcaa gaaaggtgat
    15421 caaggactcg atattttgtt tcagagactg tacactcttt gcagtcacta tgacgggatg
    15481 tactgagcga gtctctattg ctgtgttttc tgattgaggt aacggagcgt cttctaggag
    15541 cacggctgtg ttacctccag cggcgctgaa attgttcaga aaacatgtgc gcttcccacc
    15601 gacgcaatca gttcgatgcc aagggacagt tttcaacgca atgttgacat tgcgctcttt
    15661 gagatcaaga ggatagttac ggttgatctt agttttgatt ccgcaatgcg gtggtatctg
    15721 gttgttcttc atcatcatca ggaccttgat caaagcagaa acaccactgg ctgcctctgc
    15781 gtgaccaacg ttggctttcg cggacccaag atatagcggg tggtgtggca ttcgctcgcg
    15841 accaggcacg aaaactgata gaactgaatt catctcagta gcatctcctg cttgggttcc
    15901 agttccatgc atttctatgt agctaacatc cagtggattg acgttggaat tcctcatgat
    15961 ccggttaaag acggaagctt ggtcgccctc gtgaggtctt gtgatggatt ctgtttgacc
    16021 acaatgattt gtaaaagctc catcgatgac cccaaagatt ggatcgttgt ccgcttgcgc
    16081 atcttcgagc ctcttgagaa tgacggaccc cacggcgtct gctctgcagt agccgctagc
    16141 accgtcatca aaggcattac agtttcctac ccgggaaggt gtcagcacct catctaaatg
    16201 aacaagttta aaagggacac gtacctgtgg tcgataggaa gtgtccacga tcaaggccag
    16261 caaagttgtc aggattggtg agtacattgg ttcctccggc aactgcagta tcacattctc
    16321 ctctccataa atagttacac gccgtttgga ttgcagcgaa gcttgaggaa catgctgtat
    16381 cgatactcag gcttggacca gaaaatctaa agaagtagct gtttcgatgt cagcaagtct
    16441 gattcgtgtg gaaatcatag ttgacttacc ttatgcgtcc ggggacaaat gcacggtttc
    16501 cgccagggat aaaatatgtg tcgatgtttt ggccgctatt gacctctcgc caatcatcac
    16561 tagtcacccc aaaaaagaca ccaatgcggt cttgttgtgt ggaaggtgtc ctgttaggga
    16621 ccaatcctgc catttctata gcctcgtatg ttgtcgtgat ggctaacctc tgagctggat
    16681 ctgtgttttg agattctctg ggggacatgt tgaaaaatcg agcatcaaat aatcctggct
    16741 cattgatgaa gcatccatac tgaaccctgc ttgtgttctt taccttacct gctgcatcga
    16801 agtgagtttt ccagttgaag cgatcttcag gaattgtgcg atggacgtct cgtcctgcac
    16861 ttagcagctc ccaaaattcc tcattcgatg cagcttccgg gaaacgacct gaaaacccag
    16921 tgatggctat ctttgactgc tcgaatttac cagtaggcct ggcaggctgg gagtccgaga
    16981 cgccgagatt caacaaattg gtcgttgtga cattgatttt tgtggcgcgc gttattgctg
    17041 aagagaggag gtgagcagca ttagacaata cgggtgatat tgtgcattct ttgaaggact
    17101 tctgctggaa gacatcttcc acgagcgacc ggaggatgtt gtcccatcga acctgctcgc
    17161 acagagtgtc tgacacaacc gtatgcagca gggtcttgaa gtcctcagcg acgataggtt
    17221 tgccggaagc agcagataac agaggaattc gcggcttgta tgaaccaagc aattcatcag
    17281 ggaagtagct aattatctca ttaacctcat aagacccaaa cagggaagga gcatggaacg
    17341 gcgactcgtt cggtaggcaa tacgagttca aagaaactga agccagaaag ttgtgtagaa
    17401 tgcttggagg cccactgatt gttatactgt ttggcgaaac ggcgcttaga aaaagcctgg
    17461 agcttccaga tagagtctgc tacggttagt caggcgaact tccgaaacca tatcacgacg
    17521 cacgtttttt gagttgaaac tctgcagaag ttcagcggcc tgtgcttctg aagcactcac
    17581 aatcgcggac caagatcgag gtattcgact gctcggccgc tctatatcat ttcgaagctc
    17641 cagcgagcac agaccggtcc tgaaggctgc aagaacggct tcgattcctg cgggaatcaa
    17701 ctctgaaagt gttcgagagg tactgattgc agcggcagca aacgagccag tgcacagtgc
    17761 cacaagatag gtgttggcat cgctaggata aggtctggat ccttctccaa aatatctgag
    17821 catcggacag ttagctcaac gctaattaaa cttttctgga gtgcagctag tacctaatga
    17881 attgaccaat ctcacagaga cagtggagag cgaaactcaa ggctggcttt ccttctgtct
    17941 cacccaaatt tgcaagaaga tcggtaatgg tggtaaagcg aggaagcaag gcttgctgac
    18001 gagcagggag tttcccaaat tccgtacgaa aggcagcact gactttctcg aagaaggaat
    18061 gtaaggtagc attatctttg acatgaagaa gtcgacgaag gtcttgctcg aaagatgtgg
    18121 ttagatcccc aaagaggaat agttggcacg aagcttgcgt ggaccctact agtataggag
    18181 gcatggaggg gtttggctgg actgaatcat ccattgttga atgaacttca ggactcacaa
    18241 tgtaagcata gatttgaaga gatggataca aagagcatgt atcacttcat atatcttgca
    18301 aaaattgcct tcccagaggc gatcttgtga aatgtatgtc atctctatag gatggaccca
    18361 cgcagccctc gtatcccccg ggacataaca ggtctgagaa ttcggtcgca ttgcttccgt
    18421 ctcttacaac ctcagtaccg ttgattgtca ggctgacaga ttaaccatta tattcgtaca
    18481 tcaacgtcga agctgtcagg cacaagctag ttcacggttg tccgagggcc gcggcataag
    18541 cccggtcgac gcgcccgcag catcagagac tctctagcag acccaattgg ctagattctg
    18601 agctcttatc cctgtgctcg tctccagtta gaccccagta cgtcacggat ccgtcagtac
    18661 aattcggata tcgaattgat ggtgcatacg tacttgatga tataatgacg actacccaga
    18721 agacttctgt agggtcagaa agttgtagtg taatggttgg acaagggagt gtggggagga
    18781 ggtgggtgac acaactacgg agtttccaca gtattataca ggaactaaac aaggaacgat
    18841 tacagtaggg agataaaact gtcggtaatt tatctagaaa agatgtagaa gataaaaaca
    18901 aaaggttata taatcattca agttaaatta agcgattgaa ataatgtatt ctactaagta
    18961 ttataataat ctattatgtc tttagatatt acttctatct aatactaggt agttatagat
    19021 tttctaaaaa tttactagaa agaaagtctt atcttacgta acttcagtcc acaattacgt
    19081 acatccaact tatgtttcta gaacctttct ggacaaaaag ttaccaagag gtgtgacaca
    19141 taggctagtt tacggttgtc ctgagccctc gtccttttgg tccaacaaaa agatttttga
    19201 tactaatgac catttaccaa tcttggcggc ttcaacgtgt ttggaaggat gttctatggg
    19261 acctcgtgtt tggtattgaa ctacggggtc atagaagcgg tcatgatatc agtggccatt
    19321 ggaacaatca tccgggcgcg cagcgtgtcc ttgggacaat ggaaacatcc gggcatgcat
    19381 tacctgtcaa attgttgtga acggacgact gatgggacaa tgcatccggt gcacgtatgg
    19441 atgtgaccca gacgaaagag tcggccttcg gatgccgtct aatagaggat cattggcatc
    19501 ctccacccaa gcagcacgtt tcttgacggg cttttctgga tcatattact tagttgcttc
    19561 tcttattccc agcagctatt gaacatgtcc ctgtaatacg aagggcattc gtcaatcgtg
    19621 atgtgagtct caccagaagc gatactatcg atatcaatgt ttccaatgcc tatttagtat
    19681 atttgcattg cagggtagta gcatgatgta attagaactt ggtagcatcc cagtgcagga
    19741 tgtgtatggt atgtagtgtg agtactcaac ctttgacaca acgtgtgtat aggcaacttt
    19801 actgtcactg atgaacatgt aattgaggtt gtagagctga caaagagctt agcgtgtctt
    19861 ctcacacagg attctaaaac aacgcgaaag attaattaag cgcgcgcctc cagcctcttt
    19921 tttccgtagg acgtaagttc cgtgaaagtt tgcccgtact ccgctgacag ggctattctc
    19981 cacccagatt atttaaagtt gactcgatac ttgtggtctg ccagagcaat agcattctta
    20041 acggtaaagg ccagtagtgt tttgtaatac ttggcctcca ccgaaaccac attcaatgtc
    20101 catttatcga gactccattc tcaattgctc caccgtgcct gcttggaata tgactctcga
    20161 accagccagt cactattgta gtcctcttgc catcagcgaa gttctcatga tcaggcacca
    20221 ccatcttctt gtaatggggg tcctctttga cgttgatgaa gtcctgaacg tcccggaata
    20281 caatctggac gaagcagtca cactcagcaa cgttgccagc atgcagactt ccgaatattt
    20341 ggcccatcat cttcttggtt tcgctcgtgt tgtgttgctg ttttccgtca gtttggttgc
    20401 tgcttctggg ttctgtcgca gaatttgaca actggaagga aacacaccat tgtataatca
    20461 ataatcttgt tcttgatcaa cagatccttc agtaaaggtg catgattatc gcttaagtat
    20521 ctgtggtatt cgtcctcgtc catgcctgac ttgcgatagc cgcagatggt caaggcgaag
    20581 agttttttcg acattgtggt aatatttctc gggtgtgact cggatggttt cacaaatatg
    20641 aaaggattgg gttgagccag gaaaaggtat aacacattcc tttaacacct aacgtggttg
    20701 acatctactt agaagcttca tggatacact caacatgtcc caagaggtca cacatgctga
    20761 ggatttagct gctgctctct tcctggcaat cttccccgta ttcctaagca tctaacatca
    20821 gaaggaatca cgaagagatc ttggcgagct ccctttccaa cctctacctt ccatgagtca
    20881 gtcggaggtc ggtctccgcc gctctaccat acgaatgcct agcattccta ctccgactct
    20941 ggctacaatg atgcaggaag ccctctttct acccaccggc atgtgctctc cgaccctggg
    21001 acctgtaaaa gtggaaagcc cttcatcatg aggtcgaagg cttctacccc gatagtgtcc
    21061 ctttcaacac aaatcatatc tcttcaaaca cgtaataggc attgaacgaa actcaactat
    21121 caagccaacc taaatctaca aaatgtcctc caaaaacagc cctccaacaa tagatcttag
    21181 gatacccgac atgagcctac aggatggtct tcacattgac ccgctcattc tactcgtacc
    21241 aaggttgtat tgagctcgta ttgaagaata agacaaatgg tgcggtgcaa aatgctcgct
    21301 ctccgggagg cggtcacatc attcagtagg tagactcatg ggaagtgagt aaggtattat
    21361 gattgtctga gacggcgatt gtcccttatc accatgatat cccaagacgg tgttcggccg
    21421 ctctctccta tatccgacta aggtagttgc atcagcgtgg ctccctcagc cgtaacggag
    21481 actcctctgc ataaggatta ttagcgacca tccggaagcc gatggccgag cgtgcaagca
    21541 ccattttttt gcccctgcac catgcaacag ggggcctggt cccgcatgct ggtgtaacct
    21601 tacatgcgca ggacctatcc gctggcaggc atcatagcaa gcagcatagt aggggcgatc
    21661 gaaaatcata gagtgcacat aatattacat caagctagtg aaaatcatct cgcaaatcag
    21721 gtgtaggagt tgaaaagatg gtgcagaaaa gccaccccat agtgagcaaa gcatcaatac
    21781 ctaagcatat ttatcaagag atcaatcaat tgccaccccc tttcccactt tcattccacg
    21841 ttctcaagtc gcagcgacag ggatatccct ctgctcctcc tcatccctct tcatctgcgc
    21901 ctgcgcatgc tcactaagag cctccttgcc gtcgtgacca gtcataggcc tgaatccgtt
    21961 cctgaatacg gggctctcct tcaccttctg ccagtcatgc agcatgaggc cgttctccaa
    22021 cgagcatttg acctcgtcac gtccgcgagg gacgagttct tcatcgtagg cagtaatggc
    22081 atccttgatg gttgccttgt tggcacgtac gagctcaaga ccatcgagga ggtgagaact
    22141 gtcacagatg cagtggttga ggccttgacc acgatctaga aaagaattag ctcatcattc
    22201 tccgttaagg ccgagaggca gtgcaactgg gaggagacaa cacttacagg gtggcatggg
    22261 atgcgcagca tctcctacaa gggtgactct acctccacgg ttgtcccacg gttgcgtgat
    22321 ccaatagctg atgtctgcct tgtggaccag ggtgtcctcg gggatccacg tgaatgctga
    22381 tcgagcaggc tcgcccatac cttgtgcacg ttccttaatg atggcaagac gctcttcgta
    22441 gctgagtgag tgctccgggt cacccagcca ggccatggcg agatgaaaca accatgtttc
    22501 tggatggtct tgaccatcag gcatgctaga gactgtgact agtgtgagtc tcgtactcca
    22561 ttggggcaaa gcaggatatt tgcctcactc gactgaaaag cgtggtgcga cttctggctc
    22621 agagccaaat agctcgttgg aaaccgttgt ctcagatact ttgccttatc cacatctcga
    22681 tagcaaacag tcatattgtg atgacagatc ggaaacttgc tgacttgcgc tgcctctgct
    22741 ccagacatgg cgaattctcg aactttcgag cgtgggccat cggcgccaag aagtacagag
    22801 ccttgggcga tcgtgccgtc gctaaacgag gcgaacacaa ggtcaccctt ctcgctgaac
    22861 gcaagatccg taaggttctt gccgtactgg agaggataaa gatatagtca gtttagataa
    22921 tatcttactt tggaatcatg attacttggc tgatgcaatc gacagggaca agccacttac
    22981 ctggacatca attccttcag cacacaaagc gcgcattttg ctcctgggaa cgcggaatcc
    23041 cctggcgtac ggcacgccgg caagcagatc cccggtctcg gcattgatga ttgggtaatt
    23101 accaccagct tctatgggaa cgttgggatt gcaagaaatc tctgagagct tagcgaagag
    23161 tcgcttgggg aggagcttct cgagatggtc gagggaccag tgaatggcca tagtccattc
    23221 gttgctacga tagttgagtt ttgtctcctt ttcgaagatt gtatagcgaa atccatgctg
    23281 ataggtatat tttagcagat attcctaatg gaagtgggta ggaagacatg ccttttggag
    23341 agcctgggcg agtatcaagc cagtaatacc tgacgaactc agaatcgcgc agaaagccga
    23401 actctgacaa cagaactcac ctgctccaat gatgaggaca tgcatgccct tggttacatt
    23461 ctggtcggcc attgacgcag tgcttgtctc aggaatcggg tggtagagaa atcagaaggg
    23521 ctattggtga aggtgtaata acttttgaga ctgagatgtt caaaagctca atactcgtct
    23581 caataaaata tgtgttccgc cctcaggtaa tgctgtaatt tttctgggac tgctacgagc
    23641 cccgaacaag tggacatgcg gacgaaatta gtacgcagat caaaccttcg tcggcaacgc
    23701 acctccccag gcaccaacat acttctatat tttccctttg ggtggtcatg taacacggtt
    23761 cccgagcagc agattcttag attgtttaga attctctcct cgcacccgaa cttccgatgc
    23821 agtgaacaaa tagaagaccg cacgagcgtg aaccaaaagc agctctgggc agcctggttc
    23881 ggaaacatag aggatcggaa gcgttattgt tcattatgca atactcactc atgggacgat
    23941 accgtatcgc agggtgctca atccggtgtt gcaaacccat ttttgtggca tttgatggta
    24001 tgattcactg tattttcaag ttacgcccga tagctgagtt tgcaacgcca aattgttatg
    24061 gggctcggga gccggggtag aagtatgtgt gtacgggcag actattgaga ccaaacagtc
    24121 agttaaattt caactccata gcaccatgta tgttggtttt gtcattgcgt catccacaga
    24181 ccagaaagca caaattcaat ggctaaccgg ctattgatat aatacttgaa acagtgtggt
    24241 ggatgttggt tttaccgctg cacccttacc tgaacttttt taacgaatag aaaggtttag
    24301 attaagaaga aattcagcaa gtctgaggga tgaaaatata aacctgtagc ctcgttatgg
    24361 aatgttataa gagaggtgtt aatagctcta ttacaagagt atatggagga tggtaacaac
    24421 ttgttgatcc tctgagaggg cctattggcc gcgtttcata tgcttctaat tggtcaatct
    24481 acgccgcaat ttcgcttcta atttcgctgt acagtacagc cagttgtact tagatctacg
    24541 ctctctaccc ctgtagctat caaccatctt gcttctctac gcactctgca cagcaggttc
    24601 acacaactca ttacagcaag cggtactact tacgactact gactcgaaca tcatggcagg
    24661 ttattatata caatcaacca tgttcgacta ccattccaca aatcctggca gagaaagatc
    24721 aatatctatc atcttacccc agtgctatct gcgacgtggg cttccgtctc ggagctttca
    24781 aaattgtgat ttctgggccg ggctccggct cctggtgtta gcattcttcc tcgcaaagac
    24841 aatggactat gtaggtatgg gaaggtcact cgcagccgat ccgggtcctt tatcacgagt
    24901 tctcactgct gcgattacct caagtctttt ttagagccct tatgagccac aatgactaca
    24961 tttgtagaat catccatctc gccgcttttc gggctgtggc agcctcttcc ccacttgaaa
    25021 catctctatt atggttcgtc ttgcgttcaa aagcatctat tcgcgactct cccttcacac
    25081 gattcgaaag ttttcatcgt cacaggaaat tctatcgcga ccaagactcc tcttcttcaa
    25141 caagtcgaga ctttactcgg agatcaccat gcgggaacat tcaccaaaat cagacaacat
    25201 gcgccaatgg ccgatattga ccaagccacg gagatcatcg ccaaaaatcc gttggttgat
    25261 actatcttat cgttgggagg tggatctccc atcgattccg caaaaacaat atcattccgc
    25321 atgcatgaga gaaatggcaa attcctgaca catctcacga tccctacgac gctgagtgct
    25381 gctgagtgca cgataggcgg cggctacacg aaagcagacg gtgtcaagac ttcagtaatg
    25441 acgcccgaaa ttggtgtgac tgcagtattt tacgacccgg gctatgccaa atatactccg
    25501 ttgaagctat ggctatcgac tggtatgcgt gctatggacc acgccgtgga atcacaatat
    25561 cagccatacg cgtcagagat gccatggagg gcaatgtcgt cttgggcagt gtccaccttc
    25621 tttgaatgtc taccaatagc caaggcatct catcccagcg acgaagacgt tataacgaga
    25681 ttactacttg ctgcgtttgc cagcttgggc ttccgcggta agaatgtaag gggggggatg
    25741 ggattgtcgc acaccatggg acatgctttg ggtagtccgt acggaatccc tcgtaagagc
    25801 cctcgatctc cttttctaca atggcagtgc tagccacttt gtatctgatg ccaagaatct
    25861 ctttggcact tggtagtaac cgaaattggg cgaagcccct aaccgttgtt caaatcattg
    25921 cttgtcaagg caatcagaac gctaacataa ggacagatgg agagactagc tgcctcactc
    25981 tcggtcccgt ggtccagctt aaggcgcggg ccaagcaaga ggacgcaaaa caaattgcaa
    26041 gactcctgcc ttggattggc gggacgtcga gcggtgatga tctcaaagat gctttggagg
    26101 tcggatgcaa gatcagtgcg ttagtagaga gcctgggatt acatcaaagc cttacagaga
    26161 ggggtattgg cagagaccag attccaatcg tggtggaacg ggctactggt ggtttgaaag
    26221 aaggctcact atatgacatc gtcacgcttt tggtcgaggg tttatactaa caggcgggac
    26281 ttcatggtcc ctgcataaat tgcccatgac gaaaagatgc atctttagca tcttcttcac
    26341 catttggttc accccttccg tgtgatttac gccctttcat ccactcctat tggcagtgga
    26401 tattaagctg gtcgaattgt ccccatgaca ttgtgagaga cgcccttcat caagaaccgt
    26461 tcctttcaag agcagagtcc agttgctttc tgaagattct agtcaaacag aatacccatc
    26521 ggctccctaa ccttcgtcga cgcatgaagc cgtgctcact tttgttcttc cgttttctag
    26581 aagccgtata ttacagcaaa tcttcgaatc gtgcgaggag ctcttcatcc ttcgtaaaat
    26641 ggctgagcag aaacctccat gtcagaaatc atacctcctt tcgcaactga agtctcttag
    26701 ttagcgtacg cctttttcct tagtcggttt tcacaacctc cccacaaatt ttcccatgta
    26761 catctgcact cttactgtct ctccattcat cggtcttagg gaagtaggtc cattccctat
    26821 agggctgtat tctgagtagt acgcaagact gtttctaggc tctccttctc cacgaagcat
    26881 gaatagttgc tttatatctc tcattggatc aatcaagcca acaatcatct caatacttta
    26941 caatatttac ctctacacca tacgatctct caagctacta caaccctcct tcaaagatag
    27001 tcctcaagcg aacccttgca ccatcgcatc tcgggccatc aaatctccag aagaagatct
    27061 tttatcacag cacccataaa cacccatcca ttcgaaacga aaactatgac tctagccccc
    27121 cattgccttg agtcaggccc cattatgatc ccacattgat atcaagcatc cttgcagccg
    27181 tcaccttcgt atccgacttc ctttcttctc accctcctga gattcagaca accaacgtcg
    27241 ttggtacgtc ttctggtgaa ggaaatgtct atcctgggtc cataacgatg cctaaatttt
    27301 caaaccgacg aagaaccgaa caagaaccgg agtagtgtca ggaacaacgg ggtagcagct
    27361 tctttcattc ttcaacgaat tgttccggac tccagcagtg gccgatacaa ccttggaccg
    27421 ctcttctccg tcatcgagaa aagcgggtga ggggctgggg aagtcgggct cagtaacggt
    27481 cagctgcgga tgcgagttcg cgtcgctgca catgccgtgg ctatttctga aagagggcaa
    27541 tgcgaatata tttcttctgg gctgtggggt tgggatgagg cgtcgtcgcc gtcatcatta
    27601 taattcatct agagtcgact agaaccaaaa gggggaatga gattgtattc tgcaattccc
    27661 caattaggaa atgatcataa atgttcagct tactgcaatc tatggcccgt catgcattaa
    27721 tccttccttc ccacgggtac agaactcctc catagccaat tgctcatctg tttaagcttg
    27781 gtcacgacag acgcccaaat gcctcgccgg caggcttttc cagaagaacc cctgttctta
    27841 atttgcaagc acccacttaa tctcccaaag acccctataa gcatgactcg taaaggccgt
    27901 ccacccccta accacaaaat gcggactcac cgcctcgaac aactgcctcc aatccccctc
    27961 cgtcctctgc ttcgcattat gcattgtcat caccgtgatg tcgcgtctgc gatatgcttt
    28021 ctcggtctgg gcgtcaaatt cgccgcgggc gggtgacaac atatcgttga ccagaatgac
    28081 ggtttctggc gaggcttcga gaacggggat gaaggtgcgg aggagggtga tggcgtccga
    28141 gtcagagagg ttccagagga cgttgcggag gatgaaggcg agggtttggt tgtctgggga
    28201 ggagggggcg ggttgcgggg tgaagatctc gcgcttggtg taggtgattc ggggttggag
    28261 gtctggtggg agggattttt ggccttgggt gaggagttgt tccgaattgt cttggacttc
    28321 gacggagatg tcgggatatt gctctgctag atactggtag acgtgcccgt ctctagcgcc
    28381 aatgtataca accaggttgc ggtgcttgtt tcgcttgttg ctattgaacc agtcgcagaa
    28441 aagaccattt cctgggtcga gagcttttga acaaaatgaa tttatcagtg tacagtgaag
    28501 ggatttgaag aagacgtttt gatttcagaa cttacattga gtgacaccct gcattgccag
    28561 gttaaaacgg gcgaatttct ccggatgggc tttgtgccag tcatacatag aagctcccca
    28621 gctgagttcg ggtgtattag tctctgttga gtggaagttt gagaaagaac atgaacttac
    28681 gcgtgtttga aagccgacga cccagtttga aagtcgttgc gatgcttgag tgagtcggcc
    28741 aaatgcgcgc ttgcaacacg tgtctcaaac aacctgtcag cagtgaattg attatcagct
    28801 tgtggttggt gtgactgctt gatagacgtt gcatactgga atccaaccca tgccttcatc
    28861 ttcttgttcc tcaccaattc ctcggatatc acagtatggc ggaagacctg ttcggaggtc
    28921 tcttccaaga tttgctcgca ggcgaccaac cgtaatatac gcagaagctt gttctcaggt
    28981 aagccggaca gcatagccag ctctgatacg tggacctctc catcaagcgg gatcttttcg
    29041 aggatgtcga attcgagaac tgtgtacaga gcaccgtatt cccagttcga ggaaacatac
    29101 tcatgcagga atccgtgtgg tccatagagg agttttgtga gcttctgggt taagtcgagg
    29161 atgctggtct gagctgtagc gatttctgtc gtgtgggacg accatagctc agtgtaggct
    29221 ccaacggcaa gagaaggttc tttgatggat ttctccttca tgaacttttc caactggtaa
    29281 gtttgaccaa agatttcccc agcgagggtg agcatcgtgg cagtattggc ttctcgcgcc
    29341 attgttgtgg tctgcttgga acccgatcaa ttggaactct tgtgattttg aggggagtta
    29401 tttttgcata ggtagcatgg acctcgaaga catagcttac actactcagc aatgattctc
    29461 agtcgtagca atgttaaaca cctgtacttg atcacaacta tcctggagta ctgcatccga
    29521 atactcgaga tgtggtcaac caagttcggc ttccgagcat ggtgcacaaa ccgcccacaa
    29581 ggatgctgac attcgcgtcc aactcaactg acataagtca tattctttgt agttcattct
    29641 tcacattgaa ccataacata aagaagacgc tcaccatgag gcgatatttt gttatgaaaa
    29701 cccctctttt ccaactgccc cttggggcta gacgctttgg aaggccatga tacttacttt
    29761 attgcccatt gcaaaactgt tgcgactcct ccgcacccca aatctgctgc tggctgccct
    29821 cagccattga tactgaatcc ttcgttatgc ggttaaatgt acttaaatct gtataattca
    29881 gtagctttca atagtacttg tagagtttcg atggagtagg taaagtttta agtatataag
    29941 aattaccact agtatttaag aaagagtctc acatagttaa agtttatcct ggtggaatca
    30001 ataggagctc tgttaagtac ggattgattt agatattaca tcattttgta gctctgtagc
    30061 catttgagta gaacagatcg gaggaacagc agcagctccg aagcatccgc caaggattcg
    30121 caacactttt gcaatgggca ataatttatt gagatttgtt ggaccaagag accgcggccc
    30181 ttggcggacc gatgaagtac tagcttatgt ctgacaagat ttttttcata cgaatagaac
    30241 tgatctctca gaggaaacaa gataaatgaa gcgttggagc ttctctatat aaacagtctt
    30301 ccagtattag ccatgatatc ttcctcatct aaattgtgac caccaatttt gtcgcactca
    30361 caccagcctt caattcctct aatccaggtc caatagcctc aaacccgctt cccacattct
    30421 ttacctgaat ggggattttg tagtcccctt tccttaccaa gtctgccaaa gcagtcatca
    30481 cgttttgtcc tcccggtgtc tcgaataact tccgcccata tacaacgtgt ctcttgactc
    30541 catccggtac cagggtcggt gtcccggtga acacttccga gtactccttc ggtccatctg
    30601 cactgagggt atcgaagata tccttctgcg aagcactgct ggcaactgca tcaaggatca
    30661 tttctacgcc cttgccttct ggtgttgcag atttgatgtc ctcgatcaaa gatggagact
    30721 tctggtcaaa agcttgggtt gcgccaagag attccaggta gacgtgatgc ttggaggagc
    30781 tcgtcgtaag gatggtagcc gagggaagcg caaggcgcaa tatctggatt gcggaagcac
    30841 caacaccaga gctgccgcca aggacgagga tggacttcgg ctgtgggccg ctagttgtac
    30901 cgtctgggag aaacgggaga gggatctgta ggccgtagta gatggcggag ccagcggtgc
    30961 agtaacagat gctggaatca tgtgttaggg ctaccaatcg acgaatcgag gactttcaat
    31021 gtcccttgcc ccggcttatc aaacgagaat atgaaagaga aggaagaaga gaaaaattct
    31081 cgtacggtag tgatgctgcc tcctcgaagc ttatgtttcc cggcttctta gcaacgtagt
    31141 gttctggcac aacggcaacc tcctggaaag aagcagcctt cgtctcatgc ccaaatagac
    31201 tgaaaacctc gtccccggtt ttgtatctag tgatgccctc tccaacagct tccacaatcc
    31261 cggcgccgtc gatgcccaac acggtcggcc agctctcgac catggcgcca aagtacagtt
    31321 tcttccaatc taacggattc aaagcaaccg cttccatccg gatagagact tcattgtgtc
    31381 ccggggtagg tttgggaact gacacgacgg cgaagggccc cccttttcca atggcttggt
    31441 attgagtagt tgtcaattgc at
//
