LOCUS       BGC0002225             18926 bp    DNA     linear   CON 08-DEC-2016
DEFINITION  Aspergillus aculeatus ATCC 16872 unplaced genomic scaffold
            ASPACscaffold_8, whole genome shotgun sequence.
ACCESSION   BGC0002225
VERSION     BGC0002225
KEYWORDS    .
SOURCE      Aspergillus aculeatus ATCC 16872
  ORGANISM  Aspergillus aculeatus ATCC 16872
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus; Aspergillus subgen. Circumdati.
COMMENT     URL -- http://genome.jgi.doe.gov/Aspac1
            JGI Project ID: 52394
            The DNA was provided by David Culley (David.Culley@pnnl.gov)
            The strain is available from David Culley
            Contacts: David Culley (David.Culley@pnnl.gov)
            Assembly and annotation done by JGI.
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376).
            ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 17:10:02
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..18926
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[1963:5200]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1964..5200
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..18926
                     /SMILES="NC(C(C)C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..18926
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0002225"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..18926
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            1..1518
                     /locus_tag="ASPACDRAFT_119783"
     mRNA            1..1518
                     /locus_tag="ASPACDRAFT_119783"
                     /product="hypothetical protein"
     CDS             225..1121
                     /codon_start=1
                     /db_xref="InterPro:IPR008775"
                     /db_xref="JGIDB:Aspac1_119783"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PhyH"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ASPACDRAFT_119783"
                     /product="hypothetical protein"
                     /protein_id="OJJ99912.1"
                     /sec_met_domain="PhyH (E-value: 9.1e-37, bitscore: 116.4,
                     seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRSSPKSILRRVAAHEGAPKILQVLKEDGAVIIRGFLNQNLFQK
                     LNKEMEDELAKRPLICEHNGEWVSGLAGSQTRRLNQLPAFSPTFRQEILNHPLFHEICE
                     PLFGTHGCDYWMNTATVVQIGPGNAAQSLHRDQELYPVFNPIGKDAPEALVNFFCALST
                     FTDENGATRVIPGSHQWDDFTTDVTRCVPQTIPAEMEAGDCLLFSGKTVHGGGANRSKD
                     NVRRGMALGVQATYLTAEENYQHIPREIVESMTPLAQKMIHWRSSYCPGGAGLWQINGT
                     ELANEIGLKANQPKKTI"
     gene            <1964..>5200
                     /locus_tag="ASPACDRAFT_29371"
     mRNA            <1964..>5200
                     /locus_tag="ASPACDRAFT_29371"
                     /product="hypothetical protein"
     CDS             1964..5200
                     /NRPS_PKS="Domain: AMP-binding (19-418). E-value: 5.2e-88.
                     Score: 287.2. Matches aSDomain:
                     nrpspksdomains_ASPACDRAFT_29371_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (564-632). E-value: 4.5e-16. Score:
                     50.7. Matches aSDomain:
                     nrpspksdomains_ASPACDRAFT_29371_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (698-849). E-value:
                     1e-12. Score: 39.6. Matches aSDomain:
                     nrpspksdomains_ASPACDRAFT_29371_Condensation_LCL.1"
                     /codon_start=1
                     /db_xref="InterPro:IPR000873"
                     /db_xref="InterPro:IPR001242"
                     /db_xref="InterPro:IPR006163"
                     /db_xref="JGIDB:Aspac1_29371"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     284.4; E-value: 2.2e-86)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ASPACDRAFT_29371"
                     /note="GO_function: GO:3824; cofactor binding - catalytic
                     activity [PMID 48037]; GO_process: GO:8152 - metabolic
                     process"
                     /product="hypothetical protein"
                     /protein_id="OJJ99913.1"
                     /sec_met_domain="AMP-binding (E-value: 3.6e-96, bitscore:
                     311.3, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.9e-15, bitscore:
                     45.3, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 3.8e-18, bitscore:
                     54.6, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLDDNPVPPTLPYTLHGVFQQNVLDRPDASAVCAWDGDLTYREL
                     DEKSSTLAHILRHRGVQDGALVALCFDHSLWTAVAMMAVSKAGGVWFFLEPKHPVNRLR
                     QMCRSVQARMVLCSRSQASVAAELSDDQMEAPLSIEEAVLREEDPGPMDLEVVSPERPA
                     YVAFTSGSTGSPKGAVMTHQAAVTGVLHNAKPMQLDRTARILQFASFAFDISFLEHFWA
                     LLLGGCLCIPAPLDRQNNTIHAVQSLQVNWMFLTPTVARLLEPPQLPSLRTLVLGGEPV
                     TQADLDMWLPYVHLAGLYGPAECAVGIAVQPDYSRVESANNVGPPFSVACWIVSEQDPT
                     QLAPRGAVGELVVEGPSISEGYINAPEQTTRAYLTNPTWLPAARHSTKKLYRTGDLARV
                     LDDGSLLFHGRKDTQVKINGQRIELGEIEYHTRAVLGKEHLRSPPVVAEAMEVRGRALT
                     VIAFYQVEGVCQDLDHDGQDLFLPPDDGFVGRKQSYQSQLRDHLPEYMIPTSFIPVRGL
                     PLTMSGKTDRKTLREKFAQLPSDRIKAYFVDGDGGSRSTEGMPTTPLERQMQELWAATL
                     KLELEEVGRNDPWMSLGGESLAAMRLVARARKEGIAVTVPDIFRHKTIATLCQHVSVRP
                     GPETIESFPPFSLVQCQQGSTGIEELRHAAAQQCGLTPEAIEDLYPFTAMQEAVVIPPA
                     TIGVNYTLRLDVKLPAELDLEQLMRAWDMVVAANSVLRMRVVRLPADESETMVLAVTRP
                     EIPMEPLFAERFAPGVDLWGLGKPLVRVGVAPGRLVMLIQHALYDGHSLGLIFRDLEQA
                     YRGQPVAAVSYSPFVHWSTEWQDGSNKQQYWREKFAGFDGRVCPPRVADAGIGCMESQH
                     FWGSLNFRPDGFTVTSKIRVALAVVLSWHFDTCDIVLGGIYARRGAPIPGIMESPVPAS
                     AILPDRIRLDPTQSLRANVDQDQENILTMMPYEGIRPSQVLDLSEAARAASQFQTILAV
                     QQDNSSVYPEMFRDHEMGYYGPVTAHNLMMQCFLSPDRASARVSLRLSERTMQETTAWD
                     RFLAHFEAVVDAIQEKPEIPVDRLRQHLGA"
     aSDomain        2021..3217
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASPACDRAFT_29371_AMP-binding.1"
                     /evalue="5.20E-88"
                     /label="ASPACDRAFT_29371_AMP-binding.1"
                     /locus_tag="ASPACDRAFT_29371"
                     /protein_end="418"
                     /protein_start="19"
                     /score="287.2"
                     /specificity="substrate consensus: Val"
                     /tool="antismash"
                     /translation="FQQNVLDRPDASAVCAWDGDLTYRELDEKSSTLAHILRHRGVQDG
                     ALVALCFDHSLWTAVAMMAVSKAGGVWFFLEPKHPVNRLRQMCRSVQARMVLCSRSQAS
                     VAAELSDDQMEAPLSIEEAVLREEDPGPMDLEVVSPERPAYVAFTSGSTGSPKGAVMTH
                     QAAVTGVLHNAKPMQLDRTARILQFASFAFDISFLEHFWALLLGGCLCIPAPLDRQNNT
                     IHAVQSLQVNWMFLTPTVARLLEPPQLPSLRTLVLGGEPVTQADLDMWLPYVHLAGLYG
                     PAECAVGIAVQPDYSRVESANNVGPPFSVACWIVSEQDPTQLAPRGAVGELVVEGPSIS
                     EGYINAPEQTTRAYLTNPTWLPAARHSTKKLYRTGDLARVLDDGSLLFHGRKDTQVKIN
                     "
     aSModule        2021..3859
                     /complete
                     /domains="nrpspksdomains_ASPACDRAFT_29371_AMP-binding.1"
                     /domains="nrpspksdomains_ASPACDRAFT_29371_PCP.1"
                     /locus_tags="ASPACDRAFT_29371"
                     /monomer_pairings="Val -> Val"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       2450..2509
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASPACDRAFT_29371_0001"
                     /evalue="1.90E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="ASPACDRAFT_29371"
                     /protein_end="182"
                     /protein_start="162"
                     /score="26.5"
                     /tool="antismash"
                     /translation="AYVAFTSGSTGSPKGAVMTH"
     CDS_motif       2993..3076
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASPACDRAFT_29371_0002"
                     /evalue="3.30E-10"
                     /label="NRPS-A_a6"
                     /locus_tag="ASPACDRAFT_29371"
                     /protein_end="371"
                     /protein_start="343"
                     /score="32.2"
                     /tool="antismash"
                     /translation="PRGAVGELVVEGPSISEGYINAPEQTTR"
     CDS_motif       3182..3247
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASPACDRAFT_29371_0003"
                     /evalue="3.30E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ASPACDRAFT_29371"
                     /protein_end="428"
                     /protein_start="406"
                     /score="38.2"
                     /tool="antismash"
                     /translation="FHGRKDTQVKINGQRIELGEIE"
     aSDomain        3656..3859
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASPACDRAFT_29371_PCP.1"
                     /evalue="4.50E-16"
                     /label="ASPACDRAFT_29371_PCP.1"
                     /locus_tag="ASPACDRAFT_29371"
                     /protein_end="632"
                     /protein_start="564"
                     /score="50.7"
                     /tool="antismash"
                     /translation="ERQMQELWAATLKLELEEVGRNDPWMSLGGESLAAMRLVARARKE
                     GIAVTVPDIFRHKTIATLCQHVS"
     aSDomain        4058..4510
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASPACDRAFT_29371_Condensation_LC
                     L.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.00E-12"
                     /label="ASPACDRAFT_29371_Condensation_LCL.1"
                     /locus_tag="ASPACDRAFT_29371"
                     /protein_end="849"
                     /protein_start="698"
                     /score="39.6"
                     /tool="antismash"
                     /translation="NYTLRLDVKLPAELDLEQLMRAWDMVVAANSVLRMRVVRLPADES
                     ETMVLAVTRPEIPMEPLFAERFAPGVDLWGLGKPLVRVGVAPGRLVMLIQHALYDGHSL
                     GLIFRDLEQAYRGQPVAAVSYSPFVHWSTEWQDGSNKQQYWREKFAG"
     CDS_motif       4061..4165
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASPACDRAFT_29371_0004"
                     /evalue="1.30E-04"
                     /label="C2_LCL_024-062"
                     /locus_tag="ASPACDRAFT_29371"
                     /protein_end="734"
                     /protein_start="699"
                     /score="14.4"
                     /tool="antismash"
                     /translation="YTLRLDVKLPAELDLEQLMRAWDMVVAANSVLRMR"
     CDS_motif       4343..4402
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASPACDRAFT_29371_0005"
                     /evalue="1.70E-04"
                     /label="C3_DCL_135-156"
                     /locus_tag="ASPACDRAFT_29371"
                     /protein_end="813"
                     /protein_start="793"
                     /score="14.3"
                     /tool="antismash"
                     /translation="HALYDGHSLGLIFRDLEQAY"
     gene            complement(<6276..>7782)
                     /locus_tag="ASPACDRAFT_60731"
     mRNA            complement(join(<6276..6735,6842..7121,7194..>7782))
                     /locus_tag="ASPACDRAFT_60731"
                     /product="hypothetical protein"
     CDS             complement(join(6276..6735,6842..7121,7194..7782))
                     /codon_start=1
                     /db_xref="JGIDB:Aspac1_60731"
                     /locus_tag="ASPACDRAFT_60731"
                     /product="hypothetical protein"
                     /protein_id="OJJ99914.1"
                     /transl_table=11
                     /translation="MTPDLVARFWLVELHVRLPAWLRGITSASASVAVKRPGSSKKPLE
                     PAPQPAPYKPTHYRHIIYAYDVMEEKCEIPVLEHDPFDFLDPQKTLVPPENTILIDPVA
                     VGLPWFSTMKGTPQCIHWREAEAAGLELIEQVMAARGAGAVIPEKLKTSDQRRKMMELV
                     ETAVTICIYLYAVSDAARIRVLTKSIVFLFLHDDVMESKANAEGNSILEGWDTDTFKAN
                     ELEGESRNDIFLDFCREAIALDPVLGLELMQDTVRWARYSRVNSTKADKTHATWQDFRD
                     FRELDIAYDFMITAVRFGAAILYDPAERPVFEWIEKLYIRHCLYINDLYSYEKEFREHQ
                     QEGAPLHNSVHMIEQVLSVPPGSAKAILRSVLWDCERQVREEYVRLMQLPELTHTQKVY
                     LQRLIESFAGNYMYSMSTYRYARLSGKLIGPPPEDCLLKNYVQ"
     gene            <8468..>10012
                     /locus_tag="ASPACDRAFT_60732"
     mRNA            <8468..>10012
                     /locus_tag="ASPACDRAFT_60732"
                     /product="hypothetical protein"
     CDS             8468..10012
                     /codon_start=1
                     /db_xref="InterPro:IPR001128"
                     /db_xref="JGIDB:Aspac1_60732"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 202.9; E-value: 1.5e-61)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ASPACDRAFT_60732"
                     /note="GO_function: GO:4497; iron ion binding -
                     monooxygenase activity [Evidence 20037] [PMID 5506]"
                     /product="hypothetical protein"
                     /protein_id="OJJ99915.1"
                     /sec_met_domain="p450 (E-value: 2e-72, bitscore: 233.4,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMSAAICTLLAVIATTSLGLLFLSIIRRGKLPPGPPPKPIVGNLH
                     QFPKVNRAQVFDQWHRTYGPIVGLRLGLKKLILVGSYQVARELLDRRGAIYSSRPRVVM
                     AGEIANRGNHTALMPYGPKWKLHNRVHSALMNPTMVKRYQYLQDIESRQLVHDLLQGST
                     SDFGARIHRYSSSLLFALAYGRRLPTSDAFEIQENAHIAHQFINNLAAGRWLVDAFPVL
                     NYLPTWLAPWKKIGEQLYQRKFGLLQRHTALALEKPVWNWTKHFHGPKKPAEASWEELL
                     NIIGVLYEAGADTTTSALEAFVMAAVLHPDAVRRVQAEIDALVGGAARMPSFEDVQQLP
                     FVDAFVNETMRWRPIAPEGVPHSLMKEDEYEGFTIPKNSIVIANQWHMAMDPATFTDPQ
                     AFRPERWLEDPKLPISAFGFGRRACPGRHIALNSMKIVMCRLLWAYDFDHAYENGRKVT
                     IDPDNFVREGVLSKPAPFKAALRVRSPAHEKTIQSALRESEQDEDKILAHIAAGLA"
     gene            10798..12019
                     /locus_tag="ASPACDRAFT_78840"
     mRNA            join(10798..11012,11088..12019)
                     /locus_tag="ASPACDRAFT_78840"
                     /product="hypothetical protein"
     CDS             join(10887..11012,11088..11918)
                     /codon_start=1
                     /db_xref="JGIDB:Aspac1_78840"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ASPACDRAFT_78840"
                     /product="hypothetical protein"
                     /protein_id="OJJ99916.1"
                     /sec_met_domain="PF00561 (E-value: 1.4e-09, bitscore: 27.0,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.8e-12, bitscore:
                     37.4, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKDNEEKTYSEVEFLTVDGLKLRGRLYLGEANGPALVMAHGFNA
                     VKEIVIPWAAEVFQKNGISVLLFDPRNYGESEGMPRQEVDPEKQIEDYFDAVTFLRQQP
                     GIDPEAIGLWGVSTSGATAIGAACFDKRVRLIISVCPLIEATFREEMVPDVMAQIIRER
                     EALVAARTAGQQSPQPTLVPMINQVGVSPMGFNAIHGKNFYEEMPWFKETAPNFRPHTT
                     TLTYYKMLRWHPLSNIRCLSPTPIQMLIPGKDDVCPTQEQLDFFEALPGPKRMEYYEDR
                     NHHGLLLGSAFEGVMEAQVRFVQDVLAGKFALKSGSQ"
     gene            complement(12194..14498)
                     /locus_tag="ASPACDRAFT_78841"
     mRNA            complement(join(12194..12583,12662..12822,12901..13341,
                     13406..13497,13572..13686,13761..14025,14103..14166,
                     14228..14498))
                     /locus_tag="ASPACDRAFT_78841"
                     /product="hypothetical protein"
     CDS             complement(join(12418..12583,12662..12822,12901..13341,
                     13406..13497,13572..13686,13761..14025,14103..14166,
                     14228..14411))
                     /codon_start=1
                     /db_xref="InterPro:IPR001128"
                     /db_xref="JGIDB:Aspac1_78841"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 293.5; E-value: 4.9e-89)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ASPACDRAFT_78841"
                     /note="GO_function: GO:4497; iron ion binding -
                     monooxygenase activity [Evidence 20037] [PMID 5506]"
                     /product="hypothetical protein"
                     /protein_id="OJJ99917.1"
                     /sec_met_domain="p450 (E-value: 1.5e-65, bitscore: 210.8,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIAGLVLVVLLTKYLQRVFLHPLSKFPGPSIAAVSHLWEFWHDWV
                     KNGTFLEGVADLHRSYKSPVVRIAPNHLHVNDVEVYHQVFKVNTNFYKAPYFYEAFGFA
                     TSIATITNPHRHKPLRTTVAPMFTGTAVDGMSDEMYDMVRKATDLLAARSTGTGNKFNV
                     MQFLRCITTDVSCNLIFGETLDLVSNGYHSDRFLGNLDTFVENVWIMVHAPWIAQFALM
                     LPNSLTDKIVPGYAYFREQCISWIDKVRARRAKGITLMRNGRPTLFDVLMDDNPDKNYK
                     VPSKSELIDQAFLFAIAGTDTTSMATTFAVFHILNNPAVRERLCEELRGASAIIRDQYN
                     YREVRKLPYLSAVIKEALRMSSPFPGRLPRVVPPEGMKLDNKFVPGGTIISISSRCIMD
                     DPKIYPEPEKFLPERWMGENAKSMDRNMIAFGKGSRSCLGTNLAYLKMYTMLSTMFCRW
                     DLRLVSPTDHKLRYLDHALIEMKSQVVVEILADHWTT"
     gene            14976..16961
                     /locus_tag="ASPACDRAFT_119792"
     mRNA            join(14976..15185,15264..16537,16618..16961)
                     /locus_tag="ASPACDRAFT_119792"
                     /product="hypothetical protein"
     CDS             join(15027..15185,15264..16537,16618..16777)
                     /codon_start=1
                     /db_xref="InterPro:IPR001128"
                     /db_xref="JGIDB:Aspac1_119792"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 311.1; E-value: 2.2e-94)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ASPACDRAFT_119792"
                     /note="GO_function: GO:4497; iron ion binding -
                     monooxygenase activity [Evidence 20037] [PMID 5506]"
                     /product="hypothetical protein"
                     /protein_id="OJJ99918.1"
                     /sec_met_domain="p450 (E-value: 3.8e-63, bitscore: 202.8,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNATAQALVLPFITQVTRAVSLSENVKVLGGIPFAEDGTYLEWLS
                     ILGFTIGCYYVIYTFYALCFHPLRKYPGPWHLAVSNIPNRWSTISGNSSYWLYDLHEKY
                     GPIVRVAPNEISYSDPQAWQDIYGPQPNQRLGMPKDPKFFSSFEDKKTAASIITSQPKD
                     YMRMRHIYSYGFSKQVMLAKEEMIQGIIDRAMEALRQTKQQPQDIVQIFRATDFSIVTE
                     IVFGKAYHIFDRPTYQPWFKSLMGWIRSTAVITATTDYPLGKLAAWLLTPRSVLKQRNV
                     YLKYVNGEIEERIGESNAGRKDVVQLMFETTDQPKLAESDIRANLPFMVIAASETTTTL
                     MSGMIAHLLNSPDALSQLTAEVRGRFRSPSDITIATVNNLPFLNACVNEALRVYPAAPT
                     QLPRVVPGEGATVCNRWVPGGTKVYVAPYATFRSAENFYQPDAFLPQRWLPENGESFDV
                     DKKNAWRPFGLGAHECPGQVITNLITRLIMCKLLLSFDLELCADSQDWLSRQPVWIVWD
                     KPELLIKARPAAA"
     gene            complement(<17114..>18923)
                     /locus_tag="ASPACDRAFT_43554"
     mRNA            complement(join(<17114..17522,17591..17726,17901..17921,
                     17998..18162,18248..18333,18394..>18923))
                     /locus_tag="ASPACDRAFT_43554"
                     /product="hypothetical protein"
     CDS             complement(join(17114..17522,17591..17726,17901..17921,
                     17998..18162,18248..18333,18394..18923))
                     /codon_start=1
                     /db_xref="InterPro:IPR000073"
                     /db_xref="JGIDB:Aspac1_43554"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ASPACDRAFT_43554"
                     /product="hypothetical protein"
                     /protein_id="OJJ99919.1"
                     /sec_met_domain="PF00561 (E-value: 1.3e-13, bitscore: 40.2,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVEQNIAPAKLIDRFSHDGPGKCRTSEWRFEVPLNHSKPDEGTV
                     RLFARSIHCVLGVDDPELPWMLYLQGGPGLGCKTPLEYAWLPSILEKGYRVLFLDERGT
                     GQSSPITAKTLAQQGDHKKQADLLKRFRADNIVRDCEAVRKHLYQDAPADQSKWSVMAA
                     SFGGFCAISYVSMFPNSLVEVFIGGGPCPMVNEPGQVIPRLFAVAARRNEVYYKKYPED
                     VGRVKRIIKYLKENKVALSKGTLTPERFQQLGVMLGLHGGIDYIHGVVQRTDNDLDMFK
                     FLTAPTLDLIENSGMAHNVIYSLLQEPMYCQGKAGGWCADKCRKADPRFSLNERNAQIW
                     FTGEAIFSDMFESYDELKDLKPVAELLARSSDWGQLYNEAQLARNEVPVYVATAVEDMY
                     VSYDLGCHTASKVKNLQQVVNNTWYHDAVETKASEVMPALFALKEDRID"
ORIGIN
        1 gccacagccg cagggatggg ccacgtcagc acaagggatg gcgcctttca taggagagaa
       61 ggactgttga gggcacagta caaaactcga gagcctctcg cgctcatggc cttctttcac
      121 cacctgttcc tcacgcacag gattaacaca cttacttgac tccttcttgg ctgcaagcaa
      181 agaacgaaca tctagatcct cagcaaaacc ctctcgcatc cattatgaca cgctcatccc
      241 caaagtccat cctgcgtcga gtggcagctc acgagggtgc accgaagatc ttgcaggtcc
      301 tgaaagagga tggggcggtg atcatccggg ggtttctcaa ccagaatctg ttccaaaagc
      361 tcaacaagga gatggaagat gaactggcga agcggcctct gatctgtgag cacaacggtg
      421 aatgggtgtc ggggttggcg gggtcgcaaa cgcgacgttt gaatcaactg cccgccttca
      481 gcccaacctt ccgccaggag atccttaatc accccttatt tcatgagatc tgcgagcccc
      541 tgttcgggac ccatggctgt gactattgga tgaacacggc aacggtggtg cagattgggc
      601 ccggtaacgc ggcgcaatcc ctccatcgcg accaggagct gtatcccgtc ttcaatccca
      661 tcggcaagga tgcccccgag gcgctcgtca acttcttctg cgcgctgagc acctttaccg
      721 acgagaatgg ggcgacgcgg gttatccctg gtagtcacca gtgggacgac ttcaccaccg
      781 atgtgacccg ctgcgtaccg cagaccattc cggcggagat ggaggccggg gactgcctgc
      841 tcttcagcgg gaagactgta cacggtggag gagccaatcg ctctaaggac aacgttcgcc
      901 gggggatggc gctcggcgtt caggcaacgt atctcaccgc ggaggaaaac taccagcata
      961 ttccccggga aatcgtcgag tccatgaccc cactagctca gaaaatgatc cactggcgct
     1021 cctcctattg tcccgggggc gccgggctct ggcagatcaa tggcacggaa ttggccaacg
     1081 agatcgggct gaaggccaat cagccgaaga aaaccatcta agctttcgtt taaccggcag
     1141 ccggcaagtg gatggtactc gatgcaagtc agtacatggg cgtgggcttg aagtaccgtt
     1201 atatatgggt tcgtttggag ggattcggag ttgtattatg tcgttcagac acaaacgtca
     1261 gaggagtttc aacgtagaac accctgataa gcagatagaa cgggaatttg tgcttcctct
     1321 gttttcttct ctttcctctt tcctctttgt tatctagatt gattgttatg gtctagttcg
     1381 acggctcgca ttgaacgacc gggtcattct cccatatgga aaacttttat ccacgggtgt
     1441 acgaatacct ggtcatacat gcttggaccc agatcatgag ctgatcaaag gataaatgaa
     1501 tgcttaacct cggtgatgat tatgtatggc cggtaaaagg aatttgtgta tccaatgaca
     1561 gagttgcgac atggtctctg cttgaaggca tctcgttcaa acgctcgtca gatactcggc
     1621 gacggagaca tcccgtgcac tgtttccgag ttgcttttcc tgccagggtc taactggcgg
     1681 tcaaagatcg agccaaaact caactcggag gattcctgag cacgtaaggg gcttctacca
     1741 ccgtacaccg actttcaccg ggcttgcaca gatgtgcaac tgtattgcaa cgagatggag
     1801 cataagccgc atgactcggg ccttatgtag tgaattagga atataaaggg gctctccgag
     1861 agctcatcaa tgtattcaga accgacccat cctcgtcaag gctttgcggt cggtggcccg
     1921 atagttaaca gcttgcctct ccaatcactt tccagccccg acgatgactc tggacgacaa
     1981 tcctgtccca ccgacgttgc cctacaccct tcacggcgtc ttccagcaga atgtcctgga
     2041 ccgacccgat gcctcagctg tctgcgcctg ggatggcgac ctgacttatc gggaactgga
     2101 cgagaagtcc tcgaccctag cccacatcct ccgtcaccgg ggagttcaag atggggcgct
     2161 cgtggcgcta tgttttgatc attcgctctg gacggcggtg gccatgatgg ccgtctccaa
     2221 ggccgggggg gtatggttct ttctcgagcc caagcatccc gtcaatcgac tgcgccagat
     2281 gtgccgcagc gtgcaggcgc gcatggtcct atgcagcaga tcgcaggcga gtgtggcggc
     2341 tgaattgagc gacgaccaaa tggaggcacc gctcagcatc gaggaggcgg tcctgcgtga
     2401 ggaggatcct ggtccgatgg acctcgaggt cgtcagcccg gagcgccccg cgtatgtggc
     2461 cttcacctca ggctcgaccg gcagccccaa gggcgctgtc atgacgcacc aggcggcggt
     2521 gaccggcgtg ttgcacaatg cgaagcccat gcagctcgac cggaccgctc ggattctgca
     2581 attcgcctcg ttcgcctttg atatcagttt cctcgaacac ttttgggcgc tgctcttggg
     2641 aggatgtctc tgtatccctg ccccgctgga ccgccagaac aacaccatcc acgcggtcca
     2701 gagcctgcag gtcaattgga tgttcctcac gcccaccgtg gcgcggctcc tggagccgcc
     2761 gcagctgcca tctctgcgga cgctcgtgct gggcggagag ccggtcaccc aggcagacct
     2821 ggatatgtgg ctgccctacg tgcacctggc gggactgtac gggccagcgg agtgcgccgt
     2881 cgggatcgcc gtccagccgg actatagccg ggtggagtcg gccaacaatg tcgggccgcc
     2941 cttctcggtc gcttgctgga tcgtcagcga gcaagacccg acgcaattgg ctccgcgcgg
     3001 cgcggtaggt gagttggtgg tggaaggccc ctccatcagt gagggctaca tcaacgcccc
     3061 ggagcagacg acgagggcct atctgaccaa ccccacgtgg ctgcccgccg ctcgccactc
     3121 caccaaaaag ctctaccgga cgggggactt ggcgcgtgtc ctggacgatg gctccttgct
     3181 ctttcacggc cggaaggata cccaggtcaa gatcaacggg cagcgcatcg agctggggga
     3241 aatcgagtat cacacccgag ccgttctcgg caaggaacac ttgcggtccc ccccggtggt
     3301 ggccgaagcc atggaggtga gagggcgcgc cctcacggtg attgccttct accaggtgga
     3361 aggggtgtgc caggacctcg accacgacgg ccaggacctc ttcctgccac ccgacgatgg
     3421 gttcgtcggc cggaagcaga gctatcagtc gcagctccgg gatcatctgc ccgaatacat
     3481 gatccccacc agtttcatcc ccgtgcgggg gttgcccctc accatgtcgg ggaagacgga
     3541 ccgcaaaacg ctgcgggaga agtttgccca gctgccctcg gaccggatca aggcatactt
     3601 tgtcgacgga gacgggggta gcaggagcac ggaggggatg ccgaccacgc ctctcgagcg
     3661 gcagatgcag gagctgtggg cggccacgct gaagctcgag ctggaggagg tcggacggaa
     3721 tgatccctgg atgtcgctcg ggggcgagtc cctcgcagcg atgcggttgg tcgcgcgcgc
     3781 gcgcaaggag ggtattgccg tcacggtgcc cgacatcttc cgccacaaga ccatcgcgac
     3841 tttgtgtcaa catgtgtcgg tccgcccggg cccggagacc atcgagagct ttccgccatt
     3901 ctcgttggtg cagtgccagc agggctcgac ggggatcgag gagcttcggc atgctgccgc
     3961 ccaacaatgc gggctcaccc ccgaggcgat cgaggacctc tacccattca ccgcgatgca
     4021 agaggcagtg gtcatccccc ccgcaaccat tggcgtcaac tacaccctcc gcctcgacgt
     4081 caagctgccc gccgagctgg acctggagca gctgatgcgg gcctgggaca tggtcgtggc
     4141 cgccaactca gtcctccgca tgcgcgtcgt gcgactaccc gccgatgaga gtgagacaat
     4201 ggtcctggct gtgacccgcc cagagatccc catggagccg ctcttcgccg agcgatttgc
     4261 ccccggggtc gatttatggg gactggggaa gccgctggtc cgcgtggggg tggcgccagg
     4321 gcggctggtg atgttgatcc agcatgcgct ctacgatggt cactcgctcg ggctcatctt
     4381 ccgcgacctc gaacaggcat accggggcca gccggtggcg gctgtctcat atagtccgtt
     4441 tgtgcactgg tcgaccgaat ggcaagacgg ctccaacaag caacaatact ggcgagagaa
     4501 attcgccggg ttcgacggcc gcgtgtgtcc gccgcgcgtc gccgacgccg gcatcggctg
     4561 catggagagc cagcatttct ggggctcgct gaatttccgg ccggatggtt tcacggtaac
     4621 cagcaagatt cgggtggcac tggctgtggt cctctcctgg catttcgaca cctgtgacat
     4681 cgtgctcggg gggatctacg cccgtcgtgg ggcccccatc ccgggcatca tggagtcccc
     4741 cgtgccagcc tccgccatcc tgcccgatcg aatccgcctg gatcccacgc agtcgctgcg
     4801 ggccaacgtc gaccaggatc aagagaacat tctgaccatg atgccatacg aggggatccg
     4861 gccgagtcag gtcctggacc tgagcgaggc ggctcgcgcg gcaagtcagt tccaaaccat
     4921 cctggcggtg cagcaggaca actcctcggt ctatccggag atgtttcgtg accacgaaat
     4981 gggctactac ggccccgtca ccgcgcacaa cctcatgatg cagtgctttc tgagcccgga
     5041 ccgcgcatcg gcccgggtct ctctccggct aagtgagcga acgatgcagg agaccacggc
     5101 ctgggaccgc ttcttggccc acttcgaagc tgtcgtggat gctatccagg agaaacctga
     5161 gataccagta gacaggctgc gccagcacct gggggcgtag ttgctgtatc ggatagagtc
     5221 tcgcttgttg tttccatcct gccttattcc ttgtgttgtt gcgctttttg ggatttaagg
     5281 gtgccttggc gtaatgattg atgatgtcct tttcagcctt gggttgctgc tcgctcatat
     5341 cggaattctc tggacagcaa ttcctagtaa tctgaaattt tatttgtgcc tcgcatcctt
     5401 tctcactcat gaaatataca tctgctccta aatatataga cgtgaacgag agagccttgg
     5461 gctcccgacg caaccagtag tactgggtct tctgggcaat agcctttttt ttttgacgcg
     5521 ttagggcaag gtagtggatg ggccgcggta acagtgccac gatggcgaaa gagtcttacc
     5581 gcggggcagt acgcgggatc tgagacaaag gcagtcactg ggaaaagaga gaaatagaca
     5641 tataacgaat ccgtaatgga taatcagaaa agcttgatat gtggcgagtt cagcctgtac
     5701 ctgataatct catcgaaaca gccgtatagg gtgatctgaa ccctagcaca cccagtaatt
     5761 gagatatatg acccctgatc ctaaagcagc aaaccattta tctctctgac caccacccaa
     5821 atggcacgcg atgaacagta ctaggttcag gtattgtcat tcggactggt tgaaggcaac
     5881 ttgccagccc gagttcctac gaagggcgcc ccaccaataa tgctattgcc atgctggtag
     5941 cctacatccc ctgggaccct ggggggacgt ctacgtttct gccccgtgcg cctggtttac
     6001 atacttcccc tcacttttta ggcgggtgtt cgcaatatga ttgaatacca ttagctggag
     6061 ttccagttga ccttgatttc agctcaaaac atgaagagag gattcttggg gttgtttttc
     6121 aaaaagcatc tgctgagtgg cgcagtcgaa taaaagttcg tttcatcatt tgtataatct
     6181 atctatgcgg agagaagcct gaatctatcg ctgtcagtca gtgaaacagc ccttctctct
     6241 gcgtctccaa gcaggagctg gcaaccgccc gtcgctcatt gcacataatt cttcaagagg
     6301 cagtcttctg ggggcgggcc gatcagcttc ccactgagcc gggcgtaccg ataggtgctc
     6361 atggaataca tataattgcc ggcgaagctc tcaatcagcc gctggagata gaccttctgt
     6421 gtgtgggtca actcgggcag ttgcatgagc cgaacatatt cctcgcggac ttggcgctca
     6481 cagtcccaca agacggatcg gaggattgcc ttggcggagc cggggggcac ggagaggacc
     6541 tgctcgatca tgtgtaccga gttgtgcagc ggggcgccct cttgctggtg ctcgcggaat
     6601 tccttctcgt agctgtagag gtcgttaatg tagaggcagt ggcgaatgta gagcttctcg
     6661 atccactcaa agacgggccg ctcggcaggg tcgtagagga tggcagcccc aaagcgaacc
     6721 gccgtaatca taaagctata atcaagaaaa agagaagtga gcaaagagga ttccagacga
     6781 gtcagcttcc ctgagcgttg gaaaggcagg ggatgggggg gggggcgggg gttgtcccta
     6841 ctcgtaggca atgtccagct cccgaaagtc ccggaagtct tgccacgtcg catgggtctt
     6901 gtcagccttg gtgctgttga cccgagagta acgcgcccag cgaacggtgt cctgcatcaa
     6961 ctccagtccg aggactgggt cgagcgcgat ggcctcccgg cagaaatcga ggaagatgtc
     7021 attgcgcgac tcgccctcca gctcgttcgc cttgaaggta tccgtgtccc acccctcaag
     7081 gatggagttg ccctcggcgt tggccttcga ttccatgaca tctgcaacca ccattcatct
     7141 cagttatcaa gggacatttt gagcagagga atccggagaa cacaggctct taccatcgtg
     7201 caggaacaga aacacaatcg acttggtgag gacgcggatc cgcgccgcat ccgacacggc
     7261 atacagatag atgcagatgg tcacggccgt ctcgaccagt tccatcatct tccggcgctg
     7321 gtcgctggtc ttgagcttct ctgggatcac agcgcctgcg ccccgcgccg ccatgacttg
     7381 ctcgataagt tccagcccag ccgcctcggc ctcgcgccag tggatacact gcggagtccc
     7441 cttcatcgtg gagaaccacg gcaggcccac tgcaaccggg tcaatcagaa tggtattctc
     7501 gggcgggacc agcgtcttct gagggtcgag gaagtcgaag ggatcgtgtt ccaagacggg
     7561 aatctcgcac ttctcctcca tcacgtcgta cgcatagatg atatgccggt agtgcgttgg
     7621 tttgtatggg gctggttgcg gggcgggctc caggggcttc ttagagctac cgggtcgttt
     7681 caccgcaacg gatgcagaag cgcttgtgat gccccttagc catgcaggta gtcggacatg
     7741 aagctccacc agccagaaac gagcaacgag gtcgggcgtc atagctagag acactctgag
     7801 gaactgcaaa cacactgaaa agtttgccta cttctcgtat ccccttccac gctccgaaag
     7861 caagttcgat ggcagcgaag ctgaatataa agattgaggc cttgtagacg tgcgacaaag
     7921 ggagacggac gtgggaggag agaaaaagga aagatagaga gaacgcccgg aggagataga
     7981 tgatttttaa atcccttgtg agtaagacat ctgtgcccag tatcgcggaa cgtgatcccg
     8041 tcgcctgcaa ccccgtgggc ctcgcgttgc tgatcgcacc aggataggat gacgacatct
     8101 ctttcctggc aagatcgagg caggagtgga atcaagggga aggttgggcg ttcgccacgg
     8161 tctggctggt gtgtgcattg tggtataagg gatcgaccgt aggcaaggag gaatcattcc
     8221 ttgacatcag atgcaaggga gtgtggcaca gctctcggtg tactatgtaa gccggagaga
     8281 taagggcaag aagagaggcg gacggagggt ctcttcgata ttagcttatc tctctggtgc
     8341 tcgcattcgc ccctaaccta tatgttgttc tgcttccttc gtttcccatc acaagagtac
     8401 tcagagcatt ccagcggcgt tcccccgggc acacgacact ctaacaccat ctcctccacc
     8461 gtcgagaatg atgagcgccg ccatatgcac tcttctggcc gttatcgcta ccactagctt
     8521 aggcctattg tttctctcca tcatccggcg tggcaagctt cctccagggc ctccacctaa
     8581 gcccattgtg ggcaacctcc accaattccc gaaagtcaat cgcgcgcagg tctttgatca
     8641 atggcatcgg acgtacggcc cgattgtggg attgcgactg gggctgaaga agctcattct
     8701 cgtcggaagc tatcaggtag cccgcgagtt gcttgaccgg cgaggagcta tctacagctc
     8761 acgcccgcgg gtggtgatgg ctggcgagat cgcgaatcgc ggcaatcaca cggcgctgat
     8821 gccctacggc cccaagtgga agctccacaa tcgtgtacac agcgccctga tgaatccaac
     8881 catggtcaag cggtatcagt acctccagga cattgagagc cggcagcttg tccacgacct
     8941 gctccagggc tcgacctcgg actttggcgc ccgcatacac cgctactcca gcagcctgct
     9001 cttcgccttg gcctacggcc ggcggctgcc caccagcgat gccttcgaga tccaagagaa
     9061 cgcgcacatc gcccatcagt tcatcaacaa cctcgcggcg ggtcgctggc tggtcgatgc
     9121 cttccccgtg ctcaactatc tccccacctg gctcgccccc tggaagaaga ttggcgaaca
     9181 gctgtaccag cgcaagttcg gcctcctgca gcgccacacc gcgctcgcct tggagaagcc
     9241 tgtctggaac tggacaaagc acttccatgg gcccaagaag ccggctgaag cgagctggga
     9301 ggagctgctg aacatcatcg gggtactcta cgaggcgggc gcggatacca ccacctcggc
     9361 cctggaggct tttgtcatgg ctgccgtgct acacccggac gctgtccgcc gcgtgcaggc
     9421 ggagatcgac gctctcgttg gcggcgcggc gcgcatgccc tccttcgagg acgtgcagca
     9481 gctccctttc gtggacgcct tcgtcaatga gacgatgcgg tggcggccca ttgcgcccga
     9541 gggggtgccc cacagcctca tgaaggagga cgaatacgag gggttcacca tccccaagaa
     9601 ctccatcgtg atcgcgaacc agtggcacat ggccatggat cccgccacct tcactgaccc
     9661 gcaggccttc cggccggagc gctggctcga ggatcccaag ttgcccatca gtgcttttgg
     9721 cttcgggcgc cgcgcgtgtc ccggccgcca catcgccctg aactccatga agatcgtgat
     9781 gtgtcgcctg ctgtgggcgt atgactttga ccatgcctac gagaatgggc ggaaggtcac
     9841 catcgaccct gacaatttcg ttcgcgaggg agtcctctcc aaaccagccc cgttcaaagc
     9901 cgccctgcgc gttagaagcc ccgcgcatga gaagaccatt caatcggctc tccgggagag
     9961 cgagcaggac gaggataaaa tcttggcgca tattgctgcg ggccttgctt agagctgggc
    10021 tggaggtcaa aactggaaag agaaggggct gagtacagag taagagtaag gggggaggga
    10081 aataaagtta ctggaggaat tgaggtacaa gaatgattcc atagagtagg gaagatagag
    10141 tggaaaccct aatggaataa ctatcgctgc ttacaccgcc accctttcct ctgcctttcc
    10201 cccttccctc cgcggagcaa gctttcgatc atatatgtca ctttatgcga ccaggtggat
    10261 actgtctgca tgacgtatcg gaatgtcgga atatgattcc accgctaaaa cttctgtggt
    10321 cacaatatag tttgcgatcc tggcaaaagc aaggtacgga gaccgtacag atcctctccc
    10381 cttgggactg ggtgacgatc atgccacccc cagggatatc tatgccaaac ccgaaaaatg
    10441 attgcgaaat cacgcaagga actttcagag gcagccaacc agtcaatctg gcccgggtaa
    10501 tattcccgca aacctgccgg tgtggtcgat cactcaggcc ttgcatctta ggaatgccgg
    10561 gcgatgacgc tgggaacatt cttcatcctt gcttgacata cttgtcccgc acatgacagg
    10621 caaggggaat tctgtcgaac gcctgcagtc gacatgcatt gccaagtagc ctgggtcttg
    10681 cagctcagac tggcggtcag tatgtctcac actctaaact catcacacca caaaacggag
    10741 ggaaaagagg tagttgtctc cgtttcctcc gttcatgcgc gcccaattgc cccccacgaa
    10801 gtccgcttcc caactacaat cggcagctca ggaatacagt ctgcctaacc cacttgcaca
    10861 cacatacgac acactgaatc ctcataatga ccaaagataa cgaagagaaa acttacagcg
    10921 aggtcgaatt cctcacggtc gatgggctca agctgcgagg gcggttgtac ttgggcgaag
    10981 ccaatggccc ggcgttggtg atggctcacg gggtgcgtct cgccccttct tcatttctga
    11041 tatcttctcg tctccgatgg actactgacg aatgtcgact gccctagttt aacgcggtga
    11101 aggaaatagt catcccgtgg gcggcggagg tcttccaaaa gaatggcatc agcgtgctcc
    11161 tgttcgaccc acgcaactat ggcgagagcg aggggatgcc acggcaagag gtggacccgg
    11221 agaagcaaat cgaggattac ttcgacgcgg tgacctttct gcggcagcag cccggcatcg
    11281 acccggaggc gatcgggctc tggggggtgt cgaccagcgg ggccacggcc atcggggccg
    11341 cctgctttga caagcgggtg cggctcatca tctccgtgtg cccgctcatc gaggcgacct
    11401 ttcgggagga gatggtgccg gacgtgatgg cgcagatcat tcgcgagcgc gaggccctcg
    11461 tcgcggcgcg caccgccggc cagcagtcgc cccagccgac tctggtgccg atgatcaacc
    11521 aggtcggcgt cagcccgatg gggttcaacg cgatccacgg caagaacttc tacgaggaga
    11581 tgccgtggtt caaggagacg gcccccaact tccggccgca caccaccacc ctcacctact
    11641 acaagatgct gcgctggcac cccctcagca acatccgctg cctcagcccc acccccatcc
    11701 agatgctgat ccccggcaag gatgatgtct gcccgactca ggagcagctg gacttcttcg
    11761 aggccctgcc gggtcccaag cggatggagt attacgagga tcgcaaccat catggcctgt
    11821 tgctgggctc tgcttttgag ggcgtcatgg aggctcaggt gcgctttgtg caggatgtgc
    11881 tggccgggaa attcgcgctg aagagcggaa gccagtaatg tttgtgattg tgtgtgtgtg
    11941 tgtctaactc gcacatgtag cgagatcgat gagttctaaa ttgcaaatct aagacagtcg
    12001 attcgtcaag tcagcaccgc aacaagggca tagatctcag ttcgcgtagt ttgtaggtat
    12061 cccgcggaga ttagttgggc tggtaagcga gcgagcagag ctctcccaaa gaatgaatgg
    12121 gctgtccatc caacctacag ggccatggcg cgtaagtctt ggaatttgtg acttgagcca
    12181 agatggtgga tttcagctat cgagaaggaa ccttttatta cgcagacatg tacaagtacg
    12241 tcgtagagtg acgcccatcg tttgaggatc tcatgtcatt cggttaagaa aagtcgtggt
    12301 gtggagccag ggcatcaagg gccggccgaa acctgctcgt catttgagga ctaaatcact
    12361 acaattatct atcgcgcact ttgtaacggt cttcctcctc caacccaggc cgaccgttca
    12421 tgtggtccaa tggtctgcga ggatctccac caccacctgc gacttcattt caatcaaggc
    12481 atggtcgagg tagcgaagct tgtggtctgt cgggctgacc agccgaagat cccaccggca
    12541 aaacatggtc gagagcatcg tgtacatttt gaggtaggcc aggcttgagg ccagtcagca
    12601 taacaattca gggacaaaat ccggtgccgg aggggttaac gcatcgcaag gagaaaccta
    12661 ctttgtgccg agacaactcc gactgccttt gccaaaggca atcatatttc ggtccatgct
    12721 ctttgcattc tcgcccatcc agcgctctgg caggaacttc tcaggttccg ggtatatctt
    12781 tgggtcgtcc atgatgcacc gagagctgat cgagatgata gtctggacag aaaaacgcat
    12841 gagccacgga actgcacgtt agggtttaca accatcaaca ggtcaacgga aaatacgtac
    12901 cccgcctgga acaaacttgt tgtcaagctt catgccttct gggggtacca cgcgaggcaa
    12961 gcgtcccgga aaggggctcg acattcgcag cgcctccttg atcaccgcgg acaggtacgg
    13021 cagcttccgg acctctcggt aattgtactg atctctgata atggcggagg ctccacgtag
    13081 ttcttcgcag aggcgctccc ggactgcggg gttgttgaga atgtgaaaga ctgcaaacgt
    13141 cgttgccata ctcgtcgtat ccgtgccggc aatcgcgaaa aggaaggctt gatcgatcag
    13201 ctcactcttg ctcgggactt tgtagttctt gtctgggtta tcgtccatga gcacatcgaa
    13261 caaggtaggg cggccgttcc tcatcagagt gatccccttt gcccggcggg cgcgcacctt
    13321 gtcgatccat gaaatgcatt gctgtagggt cagagtcagt gggaagggac cctcgaacaa
    13381 gtccccgggg gctgggttat cgaacctctc ggaagtaggc atagcccggc acgattttat
    13441 cggtgaggct gttgggaagc atcaacgcaa actgggcaat ccagggggcg tgcaccacta
    13501 tacggattcg agtcagccac gaccatgcca atcagagcag ctcgaaaggc tgagccgcga
    13561 ggaaacccta ctgatccaca cgttttcgac aaaggtgtcc aggttgccca gaaagcgatc
    13621 cgagtgatac ccattgctga ccaggtccag cgtctcgccg aaaatgaggt tgcaactgac
    13681 gtctgtctgc gcaccacacc aacctccgaa tcagtatctt cggtcccaat tgctcggtag
    13741 ctcgatccat gcgcactcac cgtgatacac cgcaggaact gcatgacgtt gaacttgttc
    13801 cctgttccgg tcgaccgggc cgccaggagg tcggttgcct tgcgaaccat atcgtacatc
    13861 tcgtcggaca tgccatccac cgccgttcca gtgaacatgg gcgccacggt cgtccgcagc
    13921 ggcttgtgtc gatggggatt ggtgatggtg gcgatggagg tggcaaagcc gaaggcctcg
    13981 tagaaatacg gtgccttgta gaagttggtg ttgaccttga atactctgcc atcatcaagg
    14041 gtcagctccc gcgccgtgat cagatacgga agaagagaac cgcggcgtgg gtgctaacat
    14101 actgatgata aacctcgaca tcattgacgt gcaggtgatt tggcgcgata cggactaccg
    14161 gggactctat acttgttcat cagccgccgg ttgcggtctc ggactccagc atccaacaag
    14221 tgcttactgt aacttctgtg tagatcagct actccttcga ggaaggtccc gttctttacc
    14281 cagtcgtgcc agaactccca tagatgcgaa acggcggcaa tcgaaggccc gggaaatttg
    14341 ctgagtggat gcaagaatac gcgttgcaag tatttggtca gcaagactac cagcaccaag
    14401 ccagcaatca tcgagccaag atgggaagat gccagagata tcctcccccc cagcaagccg
    14461 gaatggctaa ggtcgatagg cggcaacacc atattgtttg agccccaggt ccgcagattg
    14521 gcgttctgaa tcgatcaaca tggtggaggg gcacccgggg ttccgactta cgcctaatat
    14581 atgtggaccg ctgtatcata catcagcggg tcttcgcgct tgtcccttca ttgctcttcc
    14641 catttctcgg caccttgcgt ccggggacgt atgtatttgc actgcctgaa agtcgaaact
    14701 gcggtgagag cgagacatgc ccaagcagct gcaagggttg cttgatacct tctacactcg
    14761 aaccttaccc ccttcacacc cccttgcatt gcggacgatt cctgagggta taactctggc
    14821 tttcgtgctt atgcatgcct atgcatggct ttgaggcaca actggctcct taccgggggt
    14881 ggtcgtatcg atgacgattg agaagcaagg cccggcatcc gtactatata taagcgacgg
    14941 gttatcgtcc gattttgtca gatcatccct gtcatcccag gagcccccga attgtactcc
    15001 tcccccctct tctccgtctg cacgccatga acgcaaccgc gcaggccctt gtccttccct
    15061 tcatcaccca agttacgcgc gctgtttctc tttcggagaa cgtgaaggtg ctgggtggga
    15121 tcccctttgc ggaagatgga acctatctcg agtggttaag tatcttgggt ttcaccatcg
    15181 gttgtgtacg aggctggtcc ctttcgtgaa agccccaaat ttccactggg cattgctgac
    15241 tcgttgcccg cacatcatct cagtactatg tgatctatac cttctacgcc ttgtgcttcc
    15301 atccactgcg caagtaccct ggaccatggc atctcgcggt cagcaacatc cccaaccgat
    15361 ggtcgacgat ctccggcaat tcgtcttatt ggttatacga cctccacgag aagtacggcc
    15421 ccattgtgcg cgtggctccc aatgaaatca gctattccga cccccaggcg tggcaggaca
    15481 tctatggccc gcagcccaac caacggctgg ggatgcccaa agaccccaag ttcttcagct
    15541 cctttgagga caagaagacg gccgcctcga tcatcacctc ccagcccaag gactatatgc
    15601 gcatgcgcca catctactcg tacgggttct cgaagcaggt gatgctcgcc aaggaggaga
    15661 tgatccaggg gatcattgac cgggcgatgg aggcactgcg ccagaccaag cagcaacccc
    15721 aggacatcgt gcagatcttc cgggccaccg actttagcat cgtgacggaa atcgtcttcg
    15781 gcaaggcgta ccatatcttc gaccggccta cctaccagcc ctggttcaag agcctcatgg
    15841 gttggatccg gtcgaccgcc gtcatcaccg cgaccaccga ctaccctctg ggcaagctgg
    15901 cggcctggct cttgaccccg cgcagcgtcc tcaagcagcg caacgtctac ctgaagtatg
    15961 tgaacgggga gatcgaggaa cgcatcggcg agtcgaacgc ggggcggaag gacgtcgtgc
    16021 agctcatgtt cgagacgacg gatcaaccca agctggccga gtcggacatt cgcgccaacc
    16081 tgccgttcat ggtgattgcc gccagtgaga ccacgacgac cctgatgagt ggcatgatcg
    16141 cccatcttct caactccccg gacgccctgt cgcagcttac ggcggaggtc cgcggccggt
    16201 ttcgctcccc cagcgacatc accatcgcca ccgtcaacaa cctgcccttc ttgaatgcct
    16261 gcgtcaacga ggccctgcgc gtctaccccg ccgcgcccac tcagttaccc cgcgtcgtgc
    16321 cgggcgaggg cgcaacggtc tgtaaccgct gggtgccggg gggcaccaag gtctacgtcg
    16381 ccccgtacgc caccttccgc tccgccgaga acttctacca gcccgatgct ttccttccgc
    16441 aacgctggct ccccgagaac ggagagtcct ttgatgtcga taagaaaaac gcctggcgac
    16501 cctttgggct gggcgcgcac gaatgtcccg gtcaagtgta agtggtcgag tttccctgcc
    16561 ctcccttgct ctgatatggt tagctttcca gttgtctaaa ccaatattct aaaccaggat
    16621 caccaacctc attacacggc ttatcatgtg caaactgctc ctcagcttcg atctggagct
    16681 gtgtgcggac agccaagact ggctgtctcg ccagccagtg tggattgtat gggacaagcc
    16741 cgagctgctg atcaaagccc ggcccgccgc cgcgtgaagg cgggagcttt agggctcctg
    16801 tgtgcacagc acccaaaggc acccgcccgt ataagacaac acgcggacgg ggacaacgcc
    16861 agtgctggag gccgaggtac tagacttcag ataacttcaa atagaatcta cttactcata
    16921 tcgtgcctcg cagagagtat actgaccaca tcacgtcacg gaacacccgc ggaaactccg
    16981 aagtattatt ataaccgttc tacatagaaa acctgcacgg gatgaaatag acacaataga
    17041 caaaagacca aggaggaaaa ataaacccaa gccctcaaca gtaggtatag tcaagacacg
    17101 ccgcccttca aaatcaatca atccggtcct ctttcagggc gaacaaggcg ggcatcacct
    17161 cggaggcctt ggtctccacc gcgtcgtggt accaggtgtt gttgacgact tgctgcagat
    17221 tcttgacctt ggaagcagtg tggcatccca gatcgtaact gacgtacatg tcctccaccg
    17281 cggtggccac gtagacaggg acctcgttcc gggcgagttg cgcctcgttg tagagttgcc
    17341 cccagtcgct gctgcgggcc agcagctcgg cgaccggctt gaggtctttc agctcatcgt
    17401 aggactcgaa catgtcggag aagatggcct ccccggtgaa ccagatctgg gcgttgcgtt
    17461 cgttgaggct gaagcgaggg tcggccttgc ggcatttgtc cgcacaccag ccgccggctt
    17521 tgctacatgc acaaaaaaaa gacagttaag ggctagctcc agacatctca acggggccaa
    17581 atcatcttac ccttggcaat acattggttc ctggaggaga ctgtagatga cgttgtgcgc
    17641 cattccggag ttctcaatca ggtccagggt gggggctgtc agaaacttga acatgtccag
    17701 gtcgttgtca gtccgctgga cgacgcctaa agaaaacccg attgtggtca gtaatcgatt
    17761 cttcaacagg cttctgatct cacaacaacg cgaatcgtta tggagttctt tcgccctttc
    17821 cttgattttc ttccattggt gatttttctt gggtggaagg gcgagttgag gctgggggga
    17881 atgtttcttg gcaagctcac cgtgaatgta gtcgattcca cctgcacatc accgggacgc
    17941 atcgttagtt tccatgtctt gatatcctgg ggagggtatt gcagagctac tgcttaccgt
    18001 gcaagcccag catgactccc aattgttgga atcgctcggg agtgagagtt cccttgctca
    18061 aggcgacttt gttctccttc aagtacttga tgatccgctt gacgcggcca acatcctccg
    18121 ggtatttctt gtagtaaact tcatttcgtc gggcggccac cgctgcatga tacgacggct
    18181 cgtcaacacc aacggccacc tcggtaaaag cacgagtcgt tttaaaggta gaggagggga
    18241 agcgtaccaa acaagcgtgg gataacctgg ccaggctcgt tgaccatcgg acaaggtcca
    18301 cccccaataa agacttcgac taacgagttg ggactagtcc accatcacga ttagttcaat
    18361 gaatttgcga acaatcatga aagaggcact tacaacatgg agacatagga gatggcacag
    18421 aagccgccga aactggccgc catgacgctc cacttgctct ggtcggcggg cgcatcctgg
    18481 tagagatgct tccgaaccgc ctcacagtcg cggacgatgt tgtcggcgcg gaaccgcttc
    18541 aacaggtcgg cctgcttctt gtgatcgccc tgctgggcca gggtcttggc cgtgatgggc
    18601 gagctctgcc ctgttccacg ttcgtccagg aacaagaccc ggtagccctt ctcgaggatg
    18661 ctagggagcc aggcatactc caggggggtc ttgcagccca ggccggggcc accctgcagg
    18721 tacagcatcc aggggagctc cggatcgtcg acgcccagta cgcagtgaat actgcgcgca
    18781 aagaggcgca ccgtcccttc gtcaggcttg ctgtggttga ggggcacctc aaagcgccat
    18841 tccgaagtgc ggcatttgcc cggcccgtca tgcgagaacc ggtcgatgag cttggcaggc
    18901 gcaatgttct gctcgacggc catggt
//
