LOCUS       BGC0002226             12549 bp    DNA     linear   CON 08-DEC-2016
DEFINITION  Aspergillus aculeatus ATCC 16872 unplaced genomic scaffold
            ASPACscaffold_16, whole genome shotgun sequence.
ACCESSION   BGC0002226
VERSION     BGC0002226
KEYWORDS    .
SOURCE      Aspergillus aculeatus ATCC 16872
  ORGANISM  Aspergillus aculeatus ATCC 16872
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus; Aspergillus subgen. Circumdati.
COMMENT     URL -- http://genome.jgi.doe.gov/Aspac1
            JGI Project ID: 52394
            The DNA was provided by David Culley (David.Culley@pnnl.gov)
            The strain is available from David Culley
            Contacts: David Culley (David.Culley@pnnl.gov)
            Assembly and annotation done by JGI.
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376).
            ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 17:10:04
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12549
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[138:8200]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      139..8200
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..12549
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /detection_rules="(indsynth or dmat or indole_PTase)"
                     /kind="neighbouring"
                     /product="NRPS"
                     /product="indole"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     subregion       1..12549
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0002226"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..12549
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /contig_edge="True"
                     /product="NRPS"
                     /product="indole"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /rules="(indsynth or dmat or indole_PTase)"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(<139..>8200)
                     /locus_tag="ASPACDRAFT_46595"
     mRNA            complement(join(<139..825,892..1251,1750..3996,4053..4145,
                     4214..4488,4552..7536,7606..>8200))
                     /locus_tag="ASPACDRAFT_46595"
                     /product="hypothetical protein"
     CDS             complement(join(139..825,892..1251,1750..3996,4053..4145,
                     4214..4488,4552..7536,7606..8200))
                     /NRPS_PKS="Domain: AMP-binding (18-400). E-value: 1.8e-76.
                     Score: 249.2. Matches aSDomain:
                     nrpspksdomains_ASPACDRAFT_46595_AMP-binding.1"
                     /NRPS_PKS="Domain: Condensation_DCL (601-883). E-value:
                     1.9e-32. Score: 104.4. Matches aSDomain:
                     nrpspksdomains_ASPACDRAFT_46595_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1040-1423). E-value:
                     4.2e-75. Score: 244.7. Matches aSDomain:
                     nrpspksdomains_ASPACDRAFT_46595_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (1530-1600). E-value: 1.5e-14.
                     Score: 45.8. Matches aSDomain:
                     nrpspksdomains_ASPACDRAFT_46595_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1641-1887). E-value:
                     6.1e-28. Score: 89.6. Matches aSDomain:
                     nrpspksdomains_ASPACDRAFT_46595_Condensation_LCL.1"
                     /codon_start=1
                     /db_xref="InterPro:IPR000873"
                     /db_xref="InterPro:IPR001242"
                     /db_xref="InterPro:IPR006163"
                     /db_xref="JGIDB:Aspac1_46595"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     252.5; E-value: 1.1e-76)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ASPACDRAFT_46595"
                     /note="GO_function: GO:3824; cofactor binding - catalytic
                     activity [PMID 48037]; GO_process: GO:8152 - metabolic
                     process"
                     /product="hypothetical protein"
                     /protein_id="OJJ96433.1"
                     /sec_met_domain="Condensation (E-value: 1.2e-32, bitscore:
                     100.8, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 3.8e-77, bitscore:
                     247.2, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.4e-15, bitscore:
                     45.4, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVLAEQDTVLDLFAGPVIRWPDHIAVDDGRKGTRTYRQLDEESTD
                     LAASLKANGVRPGHIVPIVTTTCIQMVVGVLGILKAGAVYVPIDRERSPRHRIEYVLNK
                     SQAKIVLYTGTEFSADQARAIRLPTASVSSEYNDQVANRIDDVLAVIFTSGTTNKPKGV
                     RVRSSSVARFVTSPGFNYDVTPADRVLLVLSVGFDACMGTMFNTLCNGGTLVLADSDSL
                     AERARESSIIIATPSILAALGPPIPTNYSKLRRIVLGGETASEHLLDLWDSVQVPIWIA
                     YGPTEATCAVLTQRLQRDPQTARFSPTRLGHPIPGSTIMLLDPKDDSLITELKTPGEIG
                     IAGPCLSAGYLGDEIQTNKKFIHLGGHTTYRTGDIAEWVENMDGTRILQFHGREDRLIK
                     NRGFLVNLDQDVDQGIIRSCPSVQAAYSLKVNGMLCTAIVSPQLDTGEVLTTWKSAALP
                     YAVPDHLIRLPKLPLSSNGKVDPHQLSSILEKRISTAQKTQRSMTSFSQLKLTPKQIVL
                     AWFQDEMKVPSTEIDLSASCVSMGVSSLAAVNLSSFCGQAGYAISVADVLEAPSLREVF
                     ARCKATSTAPSSKFSSEQTGLVTHSTLSPLQHKMVLETKVDPRVNYAQHISYYRTQDIR
                     RIKKAWETVTRAEPIFRTVFIDSESDVIQEVVTESQFHWEEQKVRSSQQVKELQDGIIR
                     RTALGMSVLVLHHEGIELPRGESMIVWTSHRALLDGFSSLLLLKKLDLALQGHEIKPSI
                     PYAQTGKDLHQLRERMKDEALRFWEDRQNELLLSKGEFNIPDTVSQDRLGPVNIEYVHT
                     ESVDRVQLSQSAKRLDVTPASLLHAAWALLVSLYSDSSQVMFGMVLSGRDLPFTWAPSV
                     IGPLINQLPYNCAINRQMSVSTFVQRVYKDIRNYARFQLFESPVGTPPITTMLVVQDTD
                     MRRPSVILPPLREPLMRESTSLPLVMEVQSSGEMRLVYRSDRFNALIIQDVAAIFQNIV
                     QLLISTEDGLTVGHCLHHSFPPPIRHNLLQLGNIDRPESRVTSSGPTLRSIFRNTVSQH
                     PDLIAVRKDTISITYRQLLDSAERVASAVLSHARPGDAVAVIADRSINWIIGVWAAVLA
                     NTAYCPIDASFPIDYQVSLVKQSRAPLVLFPSSEQRRRGRFQGVTTVATEEVLQNAKIP
                     VLRSWPTQRPSDVAYVCFTSGSTGVPKGVKCLHRGLVTLQSREEYRIFSRPGRRIAQFL
                     SPGFGGCIFEVFGTLCYGATLVLRAKDDDMLSHLGQVDATILTPSVAAEMVPWHFPNIQ
                     FVYFAGEPATEPIVARWWSPERQLYNAYGSTEATVMNTLGRLAPGLPICLGSPVPSSRL
                     YILNDDGDLVPPNTVGHIHIAGAQVSDGYINTISTKQNEFQQDPFVDGHERMYRTGDLG
                     YFDHEGNLWYCSRKDRQVKVRGYRVNLDDIAHAVYRLVPTVRKAVAVLREDGTIVLVVC
                     PKRVDEAGIREALCTALPPHYQPSQIQTLEKMPTTKNGKMDLQALKKLNARRDSGSKPE
                     TQIHPLNATARAIAEAWKRILGLEPSADINGEDNFFVLGGDSISMLKLARELNDTFRVR
                     VTVRDVVLRSVLRDLAALIDTLPKTSLGVHSAQEESTRRLGTTDLSPPEVLWVHYYNSC
                     HCPSAFNVPFHASLSPRVDFHKLAWSVEETLNRHRVLRTRIKKARNGYIRTISDQRIEV
                     VYETTVDVGEWVSEPFHLGQGLVRAAITKDTLLLNFSHLLCDNDTLTQLLQEVGDLYHG
                     RQLSAVAREYFDEEPWSFPVPLPKQLQAFWSAHLTDLEVPRPLAAQRVRSYRGASMQSI
                     IPTASAKRLRETCAGCHLSLRHFALAVVAITLQTLADTRDVLLGCPYINRPDEAGANTI
                     GLHLEPLPLRFRVANSSEATQTVEHLLRAVGTMAQSAVAHAVPWHALLALLGLPFPSTH
                     DAVFDCAVTFPDERSVEDDQRLPHIDGLIPRAVSPDGAIFALLFEWHFTADEQGVSLRL
                     GYDTDIFSSSVMNVLVRLLCVALDNMLDLNLTQTRLRHVLRQALDDACLRAGMEPDQVQ
                     DLARKSLIGAVPVDQPQQGDPPVAQIYEARPAPEGTPPSTNIVLRFHPGCYVQDTWNDS
                     FRNAEFRSCVMTEFISAVASLDEPVKELSLCNFQNINPTDPKVVLNLTQILRTLRALRM
                     NNTNEHDESNGENDLEQDEPHKFFPELPSFLADPGSRDPRTPHIYSSNYFGFYPKLDLR
                     GVHLLRFKTLALGNYAFVNDSQLQWILSHGKTLTELYLDDTPILFEVSVYNKDRAFLDS
                     GRYTHKPGLREKHFATYDKRWQHYFQAFQAGLPQLRHFRYGRSEPWWEDDMTPLERETE
                     ITVGMHDDSYMVFCDGFGPTPYMHTTVYDTDDEEPSYDGDGVDCVEEDQQALVELLEKI
                     GQPLEIVD"
     protocluster    1090..12549
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[11089:12428]"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      11090..12428
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="2"
     cand_cluster    1090..12549
                     /candidate_cluster_number="2"
                     /contig_edge="True"
                     /detection_rules="(indsynth or dmat or indole_PTase)"
                     /kind="single"
                     /product="indole"
                     /protoclusters="2"
                     /tool="antismash"
     aSDomain        complement(2284..3021)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASPACDRAFT_46595_Condensation_LC
                     L.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="6.10E-28"
                     /label="ASPACDRAFT_46595_Condensation_LCL.1"
                     /locus_tag="ASPACDRAFT_46595"
                     /protein_end="1887"
                     /protein_start="1641"
                     /score="89.6"
                     /tool="antismash"
                     /translation="SAFNVPFHASLSPRVDFHKLAWSVEETLNRHRVLRTRIKKARNGY
                     IRTISDQRIEVVYETTVDVGEWVSEPFHLGQGLVRAAITKDTLLLNFSHLLCDNDTLTQ
                     LLQEVGDLYHGRQLSAVAREYFDEEPWSFPVPLPKQLQAFWSAHLTDLEVPRPLAAQRV
                     RSYRGASMQSIIPTASAKRLRETCAGCHLSLRHFALAVVAITLQTLADTRDVLLGCPYI
                     NRPDEAGANTIGLHLEPLPLRFRV"
     CDS_motif       complement(2293..2382)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASPACDRAFT_46595_0014"
                     /evalue="5.40E-04"
                     /label="C5_LCL_267-296"
                     /locus_tag="ASPACDRAFT_46595"
                     /protein_end="1884"
                     /protein_start="1854"
                     /score="12.5"
                     /tool="antismash"
                     /translation="DVLLGCPYINRPDEAGANTIGLHLEPLPLR"
     CDS_motif       complement(2908..3021)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASPACDRAFT_46595_0013"
                     /evalue="4.80E-05"
                     /label="C2_LCL_024-062"
                     /locus_tag="ASPACDRAFT_46595"
                     /protein_end="1679"
                     /protein_start="1641"
                     /score="15.8"
                     /tool="antismash"
                     /translation="SAFNVPFHASLSPRVDFHKLAWSVEETLNRHRVLRTRI"
     aSDomain        complement(3145..3354)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASPACDRAFT_46595_PCP.1"
                     /evalue="1.50E-14"
                     /label="ASPACDRAFT_46595_PCP.1"
                     /locus_tag="ASPACDRAFT_46595"
                     /protein_end="1600"
                     /protein_start="1530"
                     /score="45.8"
                     /tool="antismash"
                     /translation="RAIAEAWKRILGLEPSADINGEDNFFVLGGDSISMLKLARELNDT
                     FRVRVTVRDVVLRSVLRDLAALIDT"
     aSModule        complement(3145..6328)
                     /complete
                     /domains="nrpspksdomains_ASPACDRAFT_46595_Condensation_DCL.
                     1"
                     /domains="nrpspksdomains_ASPACDRAFT_46595_AMP-binding.2"
                     /domains="nrpspksdomains_ASPACDRAFT_46595_PCP.1"
                     /locus_tags="ASPACDRAFT_46595"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(3649..3711)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASPACDRAFT_46595_0012"
                     /evalue="5.30E-08"
                     /label="NRPS-A_a8"
                     /locus_tag="ASPACDRAFT_46595"
                     /protein_end="1432"
                     /protein_start="1411"
                     /score="25.2"
                     /tool="antismash"
                     /translation="YCSRKDRQVKVRGYRVNLDDI"
     aSDomain        complement(join(3676..3996,4053..4145,4214..4488,
                     4552..5011))
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASPACDRAFT_46595_AMP-binding.2"
                     /evalue="4.20E-75"
                     /label="ASPACDRAFT_46595_AMP-binding.2"
                     /locus_tag="ASPACDRAFT_46595"
                     /protein_end="1423"
                     /protein_start="1040"
                     /score="244.7"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FRNTVSQHPDLIAVRKDTISITYRQLLDSAERVASAVLSHARPGD
                     AVAVIADRSINWIIGVWAAVLANTAYCPIDASFPIDYQVSLVKQSRAPLVLFPSSEQRR
                     RGRFQGVTTVATEEVLQNAKIPVLRSWPTQRPSDVAYVCFTSGSTGVPKGVKCLHRGLV
                     TLQSREEYRIFSRPGRRIAQFLSPGFGGCIFEVFGTLCYGATLVLRAKDDDMLSHLGQV
                     DATILTPSVAAEMVPWHFPNIQFVYFAGEPATEPIVARWWSPERQLYNAYGSTEATVMN
                     TLGRLAPGLPICLGSPVPSSRLYILNDDGDLVPPNTVGHIHIAGAQVSDGYINTISTKQ
                     NEFQQDPFVDGHERMYRTGDLGYFDHEGNLWYCSRKDRQVKVR"
     CDS_motif       complement(3823..3885)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASPACDRAFT_46595_0011"
                     /evalue="1.90E-05"
                     /label="NRPS-A_a6"
                     /locus_tag="ASPACDRAFT_46595"
                     /protein_end="1374"
                     /protein_start="1353"
                     /score="17.1"
                     /tool="antismash"
                     /translation="PPNTVGHIHIAGAQVSDGYIN"
     CDS_motif       complement(join(3988..3996,4053..4067))
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASPACDRAFT_46595_0010"
                     /evalue="2.10E+00"
                     /label="NRPS-A_a5"
                     /locus_tag="ASPACDRAFT_46595"
                     /protein_end="1319"
                     /protein_start="1311"
                     /score="2.2"
                     /tool="antismash"
                     /translation="YGSTEATV"
     CDS_motif       complement(join(4472..4488,4552..4594))
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASPACDRAFT_46595_0009"
                     /evalue="2.70E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="ASPACDRAFT_46595"
                     /protein_end="1199"
                     /protein_start="1179"
                     /score="23.0"
                     /tool="antismash"
                     /translation="AYVCFTSGSTGVPKGVKCLH"
     CDS_motif       complement(4787..4828)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASPACDRAFT_46595_0008"
                     /evalue="1.70E+00"
                     /label="NRPS-A_a2"
                     /locus_tag="ASPACDRAFT_46595"
                     /protein_end="1115"
                     /protein_start="1101"
                     /score="2.9"
                     /tool="antismash"
                     /translation="WAAVLANTAYCPID"
     aSDomain        complement(5483..6328)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASPACDRAFT_46595_Condensation_DC
                     L.1"
                     /domain_subtypes="Condensation_DCL"
                     /evalue="1.90E-32"
                     /label="ASPACDRAFT_46595_Condensation_DCL.1"
                     /locus_tag="ASPACDRAFT_46595"
                     /protein_end="883"
                     /protein_start="601"
                     /score="104.4"
                     /tool="antismash"
                     /translation="TLSPLQHKMVLETKVDPRVNYAQHISYYRTQDIRRIKKAWETVTR
                     AEPIFRTVFIDSESDVIQEVVTESQFHWEEQKVRSSQQVKELQDGIIRRTALGMSVLVL
                     HHEGIELPRGESMIVWTSHRALLDGFSSLLLLKKLDLALQGHEIKPSIPYAQTGKDLHQ
                     LRERMKDEALRFWEDRQNELLLSKGEFNIPDTVSQDRLGPVNIEYVHTESVDRVQLSQS
                     AKRLDVTPASLLHAAWALLVSLYSDSSQVMFGMVLSGRDLPFTWAPSVIGPLINQLPYN
                     C"
     CDS_motif       complement(5492..5578)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASPACDRAFT_46595_0007"
                     /evalue="1.50E-03"
                     /label="C5_DCL_263-294"
                     /locus_tag="ASPACDRAFT_46595"
                     /protein_end="880"
                     /protein_start="851"
                     /score="11.1"
                     /tool="antismash"
                     /translation="VMFGMVLSGRDLPFTWAPSVIGPLINQLP"
     CDS_motif       complement(6164..6235)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASPACDRAFT_46595_0006"
                     /evalue="1.30E-02"
                     /label="C2_DCL_024-062"
                     /locus_tag="ASPACDRAFT_46595"
                     /protein_end="656"
                     /protein_start="632"
                     /score="7.8"
                     /tool="antismash"
                     /translation="DIRRIKKAWETVTRAEPIFRTVFI"
     CDS_motif       complement(6908..6964)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASPACDRAFT_46595_0005"
                     /evalue="1.10E-02"
                     /label="NRPS-A_a8"
                     /locus_tag="ASPACDRAFT_46595"
                     /protein_end="408"
                     /protein_start="389"
                     /score="8.7"
                     /tool="antismash"
                     /translation="FHGREDRLIKNRGFLVNLD"
     aSDomain        complement(join(6932..7536,7606..8146))
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASPACDRAFT_46595_AMP-binding.1"
                     /evalue="1.80E-76"
                     /label="ASPACDRAFT_46595_AMP-binding.1"
                     /locus_tag="ASPACDRAFT_46595"
                     /protein_end="400"
                     /protein_start="18"
                     /score="249.2"
                     /specificity="substrate consensus: Trp"
                     /tool="antismash"
                     /translation="RWPDHIAVDDGRKGTRTYRQLDEESTDLAASLKANGVRPGHIVPI
                     VTTTCIQMVVGVLGILKAGAVYVPIDRERSPRHRIEYVLNKSQAKIVLYTGTEFSADQA
                     RAIRLPTASVSSEYNDQVANRIDDVLAVIFTSGTTNKPKGVRVRSSSVARFVTSPGFNY
                     DVTPADRVLLVLSVGFDACMGTMFNTLCNGGTLVLADSDSLAERARESSIIIATPSILA
                     ALGPPIPTNYSKLRRIVLGGETASEHLLDLWDSVQVPIWIAYGPTEATCAVLTQRLQRD
                     PQTARFSPTRLGHPIPGSTIMLLDPKDDSLITELKTPGEIGIAGPCLSAGYLGDEIQTN
                     KKFIHLGGHTTYRTGDIAEWVENMDGTRILQFHGREDRLIKN"
     CDS_motif       complement(7049..7129)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASPACDRAFT_46595_0004"
                     /evalue="5.10E-06"
                     /label="NRPS-A_a6"
                     /locus_tag="ASPACDRAFT_46595"
                     /protein_end="361"
                     /protein_start="334"
                     /score="18.9"
                     /tool="antismash"
                     /translation="TPGEIGIAGPCLSAGYLGDEIQTNKKF"
     CDS_motif       complement(7262..7288)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASPACDRAFT_46595_0003"
                     /evalue="1.40E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="ASPACDRAFT_46595"
                     /protein_end="290"
                     /protein_start="281"
                     /score="5.5"
                     /tool="antismash"
                     /translation="YGPTEATCA"
     CDS_motif       complement(7706..7753)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASPACDRAFT_46595_0002"
                     /evalue="1.70E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="ASPACDRAFT_46595"
                     /protein_end="165"
                     /protein_start="149"
                     /score="17.5"
                     /tool="antismash"
                     /translation="VIFTSGTTNKPKGVRV"
     CDS_motif       complement(7934..7975)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASPACDRAFT_46595_0001"
                     /evalue="2.40E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="ASPACDRAFT_46595"
                     /protein_end="89"
                     /protein_start="75"
                     /score="17.5"
                     /tool="antismash"
                     /translation="LGILKAGAVYVPID"
     gene            <8799..>10209
                     /locus_tag="ASPACDRAFT_46596"
     mRNA            join(<8799..9167,9222..9366,9428..9636,9693..9792,
                     9896..>10209)
                     /locus_tag="ASPACDRAFT_46596"
                     /product="hypothetical protein"
     CDS             join(8799..9167,9222..9366,9428..9636,9693..9792,
                     9896..10209)
                     /codon_start=1
                     /db_xref="InterPro:IPR001509"
                     /db_xref="JGIDB:Aspac1_46596"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score: 42;
                     E-value: 1.3e-12)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ASPACDRAFT_46596"
                     /note="GO_function: GO:3824; coenzyme binding - catalytic
                     activity [PMID 50662]; GO_process: GO:44237 - cellular
                     metabolic process"
                     /product="hypothetical protein"
                     /protein_id="OJJ96434.1"
                     /transl_table=11
                     /translation="MNLALPPGSTVVVTGANGYLASHTSNELLKLGYRVRGTVRSPKPW
                     LNAFYEREYGPNRFHTVLVPDFRDPEAIEAILTGADGVVHLVTNLLLSLRTRSTLSMSS
                     FIFHLYCFSFPNLQPYVSNVVPWSRQATLSVLQAASQVSSMRRVVFISSSMALYTPNPG
                     QQGVLVDQDTWNVSAVLKALSPSWNLKSQIHDSAPPGVQKRQVEVYSACKMICEWEAWE
                     WVRCHRPAFEFNTVVAAFAVGKILMDEIPGSTMNWVRGLLHGDCTPMTLVPPKWFVDVE
                     DIARLFVIALLEPTVASERLFAFGESANWTDVLTILEQLQPENPLIPRPMPGELHDCAD
                     IQPRGRAMQLLREFYGQPGMTPIAMSIARGIGCEPLKN"
     gene            complement(11081..>12428)
                     /locus_tag="ASPACDRAFT_1890851"
     mRNA            complement(join(11081..11189,11260..>12428))
                     /locus_tag="ASPACDRAFT_1890851"
                     /product="hypothetical protein"
     CDS             complement(join(11090..11189,11260..12428))
                     /codon_start=1
                     /db_xref="JGIDB:Aspac1_1890851"
                     /gene_functions="biosynthetic (rule-based-clusters) indole:
                     dmat"
                     /gene_kind="biosynthetic"
                     /locus_tag="ASPACDRAFT_1890851"
                     /product="hypothetical protein"
                     /protein_id="OJJ96435.1"
                     /sec_met_domain="dmat (E-value: 6.9e-123, bitscore: 398.4,
                     seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGSSTTKDVKEGGAGAKPYLHLSKSLRFSNLDEHQYWHHHGPML
                     GKLLFDGNYSVHRQYEYLCLFAHLIVPSLGPFPSPGRELFQCILGSTGPFELSQNFTKS
                     RSTTRIAFEPTSHRATTGQDPFNRALLPCALHDLKATGAAINLDLHHALLERLTLSDSD
                     VARLPPTEIAKLPFKTQTILALDLDPAGISVKEYFYPTLKAQVTAQSATQLCLDAIRTI
                     DSEQLFAQGCDALQEYLQQPSQKTDIFLVSCDLVDPHRTRLKFYLAEFDVRFDRVIEHW
                     TMGDRLAKEDPDITEGLSMLEELWRALDIVEGPRAYPTRPSQPGDPPTYLPLMLNYEIH
                     PGRRAPIPKFYFPISGIPDTKIAAVLTDFFERHDMSDQAAVYAANLQNYFAGENLDETT
                     HHQAWLSFSYARSKGPYLTVYYH"
ORIGIN
        1 ttcttttcct ctatgttctt tttgtaggat tggaagaatg ccatctgggc ttcctcaatg
       61 caaagagtag cgataacctc ctttttagcc ttcatatata tcgtatcatc ctgaggttct
      121 atgacctctg tggggcctct aatccactat ctccaatggc tgcccaatct tctccagtaa
      181 ctccaccaac gcctgctgat cttcttccac acaatccact ccatcaccat cataggatgg
      241 ctcctcgtca tcggtgtcat agaccgtggt atgcatatac ggtgtcggcc cgaacccgtc
      301 gcagaagacc atgtaactgt catcatgcat cccaactgta atctccgtct cgcgctccaa
      361 gggcgtcatg tcatcctccc accacggttc cgagcgcccg tagcggaaat ggcgcagttg
      421 cgggagcccc gcctggaagg cctggaagta gtgctgccag cgcttgtcgt acgtcgcaaa
      481 gtgtttctcg cgcagccctg gtttgtgggt gtatcggcca gagtctagaa aggcccgatc
      541 tttgttgtag acggagacct cgaagaggat gggggtgtcg tcgaggtaga gctcggttag
      601 ggtcttgccg tgcgagagga tccattggag ctgggagtcg ttgacaaagg cgtagttgcc
      661 cagggccagc gtcttgaagc gcaggaggtg gacccctcgt agatccagct tgggatagaa
      721 gccgaagtag ttgctggagt agatgtgagg tgttcgaggg tcacggctgc cggggtcagc
      781 caagaaggat ggaagctcgg ggaagaattt gtgcggttcg tcttgctaga acttagttag
      841 ggactgggag acgcgaaaag ccaaggagaa taaagaatga gagcgtccta cctcaagatc
      901 gttttcgccg ttgctttcgt cgtgttcatt agtattattc atccgcagtg cgcgcagagt
      961 gcgcaagatc tgggtgagat tcaggaccac cttggggtcc gtcgggttga tgttctggaa
     1021 gttacacaga gacagctctt tcacaggctc gtcgagggac gccaccgccg agataaactc
     1081 agtcattaca caggagcgga actcggcatt ccgaaaggag tcattccagg tatcttggac
     1141 ataacagccc ggatgaaagc gaagcacgat gttcgtagac gggggggttc cttcaggcgc
     1201 gggacgagcc tcataaatct gcgcaactgg aggatcacct tgttgcggtt gctttgattg
     1261 acatagcttg cttgcgtgaa gtactgtgtc gatgagtaca gggttcagtg tatataaggg
     1321 aaggggaatt tatgccggcc caggcgctga catccagata taacctgtgc accagtcgtg
     1381 cccgagttct gtcttcgaga atctcctgaa atctttctcg gctttctttc tggagataca
     1441 cggtgatcac cttcagcagt tccctgatcc acactagctt cttcagcaaa ggtttccact
     1501 gggactttgt gtcttgaaaa tgagtcaatt tgcctttgca tcattcacaa aactggagag
     1561 cgacccttag catgccggcc ggatcgtgtt cagcatcaga caacccatca tcaaatcacc
     1621 actccaagct atttggcaag aattttggac actccatggc agaggacgaa actgctttta
     1681 attcaattga tcattccaaa cacctaaatt acacagtata ttcttcagtc acaaataata
     1741 aggtcagaca tcaaccggaa cagccccgat caaactttta cgcgccaaat cctgcacctg
     1801 gtcaggctcc atccccgcgc gcagacaagc gtcatccagg gcttgtcgta gcacgtgtcg
     1861 caaccgcgtc tgcgttagat tgagatcaag catgttatcc agagcgacgc ataacagtcg
     1921 aaccagtaca ttcatgacag aagaagagaa aatatccgta tcatacccga gccgcagtga
     1981 taccccctgc tcatcagccg tgaagtgcca ctcgaacagg agagcaaaga tagcgccgtc
     2041 gggagagacc gcgcgcggga tcagtccatc aatgtgcggg agccgctggt catcctcaac
     2101 actgcgctca tccggaaagg tgacggcgca atcaaacacg gcatcgtgag tggagggaaa
     2161 tgggagtccc aagagcgcca gcaacgcatg ccacggaacc gcatgtgcta cggcggactg
     2221 cgccatcgtt cccactgcac gcagcagatg ttcaactgtt tgtgttgctt ctgaggagtt
     2281 cgccaccctg aagcgaagag gcagcggctc caggtggagt ccgatcgtgt tggcgcctgc
     2341 ttcatcggga cggttgatgt aagggcatcc gagcaggacg tctcgggtat cggccagtgt
     2401 ctgcaaagtg atcgcgacaa cagccagggc gaaatgtcgc agcgataaat ggcaacccgc
     2461 acaggtctcc cggagacgtt ttgctgaggc ggtgggaatt atggattgca tagaggcacc
     2521 acggtaagaa cggactcgct gcgccgctag aggacgtggc acctcaaggt ccgtcagatg
     2581 agcactccag aaggcctgta actgtttcgg caatggcact gggaaggacc agggttcctc
     2641 gtcgaagtat tcacgcgcca cagcagatag ttgtctcccg tgatacaaat ccccaacctc
     2701 ctgtaggagc tgtgtcagag tatcattatc acagagcaga tgagaaaagt tgagaagcaa
     2761 tgtatcttta gtaatggcgg ctcggaccaa gccttgtcca aggtggaacg gctcactgac
     2821 ccattcccct acatcgactg tcgtctcata taccacctca atgcgctggt ccgagatggt
     2881 gcggatgtac ccattacggg ccttcttgat gcgagtcctt aatacgcggt ggcgatttag
     2941 tgtctcttct acactccaag cgagtttgtg gaaatcaaca cgtggcgaaa ggctggcatg
     3001 gaagggaaca ttgaaagcgc ttggacaatg acagctgttg tagtaatgta cccacagcac
     3061 ttcgggagga gatagatcag tggtccccag gcgcctagtg ctctcctcct gcgccgaatg
     3121 tacgccgagt gaagtcttgg ggagggtatc gatcaaggct gcaagatccc gcaggacaga
     3181 ccgcaacacg acatcgcgga ccgtcacccg aacccgaaag gtatcgttca gctcgcgcgc
     3241 cagtttaagc attgagattg agtctccgcc gagtacaaag aagttatctt ctccatttat
     3301 atcagcagag ggctcaaggc ctaaaatgcg tttccaggct tcagctatag ctcgcgccgt
     3361 tgcattgagt gggtggattt gcgtttcggg tttcgacccg gagtctctcc tggcgttgag
     3421 cttctttagt gcttgcaggt ccatctttcc gtttttcgtc gtcggcattt tctccagtgt
     3481 ttgtatctga gagggttgat aatgaggggg tagggcagtg cacaaggctt cacgaatacc
     3541 agcctcatcc accctcttcg gacacacaac gagcacgatt gtaccatctt cacgcagaac
     3601 cgccacggct ttgcggactg tgggcaccag gcggtagact gcatgcgcga tgtcgtcgag
     3661 gttcactcga tatccgcgga ccttcacctg gcggtctttg cggctgcagt accaaagatt
     3721 gccctcgtgg tcaaagtagc ccaaatctcc ggtgcgatac attctttcgt gcccatcgac
     3781 aaaagggtct tgctggaatt cattctgttt tgttgatatc gtattaatgt atccatcact
     3841 cacctgcgcc cccgcaatgt ggatgtgtcc gaccgtgttc ggtggaacaa ggtccccgtc
     3901 gtcgttcaat atatacagcc gggaggacgg gacgggacta cccaagcata ttggtaaacc
     3961 gggggctagt cggcctaggg tattcattac cgtagcctag cagattgcat agttagtgag
     4021 gagagcaatg gcagaagaag gaaggtgtct acctcggtgg agccgtaagc attgtacagc
     4081 tgccgctctg gggaccacca acgggcgaca atgggctctg tggccggttc gccggcaaaa
     4141 tagacctacc agccatgtgg tgtcagcaat gtcatctaga gaaccaggag aggcgaacag
     4201 atgccacact cacaaactgg atgttgggaa agtgccaggg aaccatttcg gcggcaacgg
     4261 atggggtaag aatggtggcg tccacctggc ccagatgtga cagcatgtca tcgtcctttg
     4321 ctcgtagcac caaagtggca ccataacaca aagtaccaaa gacctcgaat atgcaacctc
     4381 caaagccagg agagagaaac tgggcaatcc gacgtcccgg tcggctgaag atccgatatt
     4441 cctcgcggga ttgaagggtt actaatcccc tgtgaagaca ctttacacct gtttgcaatg
     4501 gaatattaga cgaaaagcga gctttggggc caaatcctcg aggagacaca cctttgggaa
     4561 cgccagtcga cccggaggta aaacagacgt atgccacatc acttggcctt tgtgtcggcc
     4621 acgatctcaa aacgggtatt ttggcgttct gtagaacttc ctcagtggca acagttgtca
     4681 cgccttggaa tcgccctcgt ctgcgttgct ctgacgatgg aaatagcact agaggggcac
     4741 ggctttgctt caccagtgaa acttgatagt cgattggaaa tgaagcatca attgggcaat
     4801 aggccgtgtt agccagcacc gcagcccaaa ccccgataat ccagttgata gatcgatcag
     4861 caatcacggc aacggcatct cctgggcgcg catgcgaaag gacggcagaa gccacacgct
     4921 cagccgagtc gagtagttgg cgatatgtta tggaaattgt gtcctttctt acagcgatga
     4981 ggtcgggatg ctgactcact gtgttccgga agatgctgcg gagtgtcggt ccagagctgg
     5041 tcactcgtga ttctggccga tcgatattac ccagctgtag gagattgtgt cgtataggcg
     5101 gtgggaaact gtggtgaagg caatgcccta cagtgagacc gtcttcggtg ctgattagaa
     5161 gctggacgat gttttggaag atagctgcca cgtcctgtat tattagagca ttgaaccgat
     5221 cactgcgata cacaagacgc atctcgcccg agctttgaac ctccatcaca agaggaaggc
     5281 tggtagattc tctcataagt ggttcacgca gtgggggcag gatcactgat ggcctgcgca
     5341 tgtcagtgtc ctgcaccacg agcatagtgg taatcggcgg ggtgcccacg gggctctcaa
     5401 aaagttgaaa tcgcgcgtag ttgcggatgt ccttataaac gcgctggacg aacgtagaca
     5461 cggacatttg tctattgatc gcgcaattgt atggcagctg attgatcaaa ggaccgatca
     5521 cagacggggc ccaggtgaaa ggtaagtccc ggcccgagag caccatccca aacatcacct
     5581 ggctggaatc agagtacagt gagaccagca aggcccaggc agcgtgtaga agtgaggcag
     5641 gggttacgtc caatcgtttt gcgctctggc tcagttgcac acggtccacg gattccgtgt
     5701 gaacgtactc gatattcacc gggccaagcc tgtcctggga tactgtatca ggaatattga
     5761 attcgccttt ggacaatagc aactcgtttt gacgatcttc ccagaacctc aatgcctcat
     5821 ccttcatccg ttctcggagc tggtgcagat cctttcctgt ttgcgcatat ggaatagagg
     5881 gtttgatttc gtgtccttga agtgccagat ccagcttttt caacaatagg agacttgaga
     5941 acccatccaa cagagcacga tgagaggtcc acactatcat gctttcaccc cgtggcagct
     6001 caatgccttc gtggtgtagt accaaaacgg acatacctag agcggttcgt ctgataattc
     6061 catcctgaag ttccttgact tgctgcgagg agcgaacttt ttgttcctcc cagtggaatt
     6121 ggctttccgt taccacctct tgaataacat cggattcact gtcaatgaaa accgtccgaa
     6181 aaatcggctc tgcgcgcgtc acagtctccc atgccttctt gatgcgcctg atatcctggg
     6241 tgcgatagta ggaaatgtgt tgtgcataat tcactcgggg gtcaaccttt gtctccaata
     6301 ccatcttgtg ctgcagcgga ctaagggttg aatgcgtcac gagacctgtc tgctcgctgg
     6361 aaaacttgct actaggcgcg gtcgatgttg ctttacatcg ggcaaacacc tccctgagtg
     6421 acggtgcttc gagaacatca gctactgaga ttgcataacc agcctgcccg cagaaggagg
     6481 acagattgac tgcagcgaga gaactgactc ccattgacac acacgaagca ctcaagtcaa
     6541 tctcagtgga aggaaccttc atctcatcct ggaaccaggc caggacaatc tgctttggcg
     6601 tcagtttcaa ttgggagaat gaagtcattg atctctgggt tttctgggct gttgaaattc
     6661 tcttctccaa aatggatgag agttgatgcg gatccacttt gccattggag ctcaagggca
     6721 gcttgggcag ccgaattaag tggtcgggaa cggcgtaggg cagggccgct gacttccagg
     6781 tggtcaacac ctctccggta tccagctgcg ggctgacgat ggctgtacag agcattccat
     6841 tgaccttcaa tgaataagcc gcttgcactg aggggcacga tcggatgatc ccctggtcga
     6901 cgtcctggtc taggttgact aggaaccccc ggtttttgat caagcgatct tcacgcccat
     6961 gaaactgcag aatgcgagtg ccatccatgt tctctaccca ctcagctatg tctcctgtgc
     7021 ggtatgttgt atggccaccg agatgaatga acttcttgtt ggtttgaatc tcgtcgccga
     7081 ggtagccggc cgacagacag ggtcctgcaa tcccgatctc gcctggcgtc ttgagctcag
     7141 tgatgaggct atcatctttt gggtctaaaa gcataatcgt ggaacctgga atcggatgtc
     7201 cgagtcgcgt aggcgagaac cgtgctgttt gcgggtcacg ctgtaatctc tgagtcaaga
     7261 cggcgcaagt ggcctctgtc ggcccatagg caatccagat cggtacttgt acgctatccc
     7321 ataggtcaag gagatgttct gaggcagtct caccccccaa gacaatgcgc ctcaatttcg
     7381 aataattcgt ggggataggg ggcccgagcg ccgccaggat cgaaggggtg gcaatgatga
     7441 tgctgctttc tcttgcacgc tctgccagag aatccgagtc ggccaggact aacgtacccc
     7501 cattgcacag tgtgttgaac atggtcccca tgcacgctgc aaaattcact gtcagcatga
     7561 taaccctcat cggaatgggt cgatggaaac ttgcaagata cgtaccatcg aagccaacgg
     7621 ataagaccag caagacccga tcagctggcg taacatcgta gttaaaccct ggagaagtca
     7681 caaagcgcgc taccgagctg cttctaaccc ggacaccttt gggtttattc gttgtgccag
     7741 aggtgaatat gacagcgaga acatcgtcga tgcgattggc tacctggtcg ttatattcag
     7801 aagagaccga agccgtcgga aggcgaattg ctcttgcctg atcggcggag aactctgttc
     7861 ccgtgtatag cacgattttg gcttggcttt tgtttaagac atactctatg cggtgacggg
     7921 gacttcgttc tcggtcgatg gggacataca cagcgcctgc tttcagaatg ccaaggaccc
     7981 ctaccaccat ctgtatgcag gtggtagtaa cgataggcac tatgtgacct ggtctcactc
     8041 cgttggcctt caaggatgct gccaggtccg tggactcttc gtccagttgt cggtatgtcc
     8101 tcgtgccctt gcgcccatcg tctaccgcga tatggtcggg ccagcgaatc accggcccag
     8161 cgaaaagatc taaaacagtg tcttgctcgg caagcaccat gacaactgag ttttatgagt
     8221 ctatttccct caatccttga atctttagtc gtgcccttat atatcatttc gatatttgcc
     8281 caagagatgc aaagatcggc agaggagcgt gggtcaagat gcagtgtgga ttgaaggggt
     8341 caaaagacgt cagaaaacag gcattcgaaa acgagcccac ccaccggggt ccagcgccat
     8401 ggtcaggtca ccgatctatc gccatcgcgg gcgcttgagt catgtgtcat gtcctctgtc
     8461 atggcaatgt aatggtggat tacgttgttt gccttctgca cggcatagtc ctccggcatg
     8521 tccgaccctc ctcatccaaa gattctagac cgacacacag cgagctggaa gcactcggga
     8581 ttacgacaga ttgacaccga accagatctc tgctgcccat ctaagctttg tgggtccaga
     8641 tctggtgagc ttctcatcgg caatctgctt tcccgcttgc cgagccatga tcatgaacaa
     8701 taaaatgccc ccggattatc attgacctag gctaagccgc gcttttgatg atcattgaaa
     8761 tgttgataca gaagaataca gattgatttt tccctgagat gaacctcgct ctccctccag
     8821 gatctacagt cgtcgtgacg ggagccaacg gctacctggc gtcacacacc agtaatgaac
     8881 tgctcaaatt ggggtaccgc gtgcgcggca ccgttcgcag ccctaaacct tggctaaatg
     8941 cgttttacga gagagagtac gggccgaaca ggtttcacac agttctcgtg ccggactttc
     9001 gtgatcccga ggcaattgag gctatactga ctggcgcgga tggggtcgta cacctggtga
     9061 ccaacctcct tctctccctg cggacacgat ccacactttc catgtcatcg ttcatttttc
     9121 acttgtactg cttctccttt cccaatctac aaccgtatgt ctctaacgta tgtggcttcg
     9181 tgtaggtctc cgactttaca ctgggaactg acatcaatga ggtggttcct tggtcccgac
     9241 aagcaacgtt gagcgtctta caggcggcgt cacaagtgtc ttccatgcgt agggtggtgt
     9301 tcatctcctc ttcaatggcg ttatatactc caaaccctgg acagcaaggc gtgttggtcg
     9361 accaaggtga gcataaacct aaacgaaatg gctgtttggc actaacctga atttcaaccc
     9421 gaatcagata cctggaatgt gtccgctgtt ctcaaagcct tatcgccctc ttggaacctt
     9481 aagtcgcaaa tacatgactc cgcgccccca ggggtgcaga aacggcaggt cgaggtatac
     9541 agcgcctgta agatgatctg tgagtgggag gcgtgggaat gggtgcgctg ccaccgacct
     9601 gcctttgagt ttaacactgt agtcgcagcg tttgcggttt gttctcatcc ctccaattcc
     9661 tggcctctgt ttcactcgct aaacaagaac aggtcggcaa gatcctaatg gacgagatcc
     9721 ccggctcgac catgaactgg gtacgcggcc tgcttcacgg tgactgtacc ccaatgactc
     9781 ttgttccacc cagtgagctt ctcagccttt cctttcgttg tcatcctctt tgccgttcaa
     9841 ttcaggccct cctcttgtcg gacttagtgg atgaccacaa actgattcgt cccagagtgg
     9901 tttgtcgacg tcgaagatat cgcccggctg tttgtgattg ctttgctcga gccgacagtg
     9961 gcctcggaac gcttgttcgc ctttggtgag tcggccaact ggacagatgt cctcactatt
    10021 ctggagcagc tacagcccga gaaccctttg attccacgcc cgatgcccgg ggagttgcac
    10081 gattgcgcag acattcagcc ccgcgggcgg gcgatgcagt tgcttcgcga gttttatggc
    10141 caaccaggca tgacgcctat tgcaatgagt attgcccgcg gaattgggtg tgagcctttg
    10201 aagaactgag aaaggatatc tcgaagactg gaggattctg ctggttcttt ttgctttttc
    10261 ctggtcgttt atctttccct ttcttttctt tttctcttat cggcaacaaa gatcacaggg
    10321 aaaatggaag actcaaggag gctgggtgca ggtcgagtcc cgcagaattt gatgttaggg
    10381 ttctgggcag actgcgcaag ggataggagt cacttctgca ggtcacgttg tgcggtaaag
    10441 gatcaaggct ttcactagga gtaccaattt aaatccattt caagcctccc ggaaaaggca
    10501 tatactaagt cgaagaccgt ataacagatt gcacagtcag acagaaagtg aagaagtgaa
    10561 gtaggagaat gagaagagaa gcagggaaag aatgtgagga ggcctgaatc ccgggccctg
    10621 gcatttcccg ccgcgtcact cccattgggc ggatcaatcg gccggcaaga ccagaagaat
    10681 gtactgtaca tggacatggc tcaatggcgc atgctcaata ggtggttggt atgatccttt
    10741 caaatgtcat agagctgcca aatcgctgtc agacggttat ggtggaccca ggctcagaaa
    10801 tatatctggc gcgacctttt tgcgcccatc acccagccgc ctcgaccaca gttttgtcca
    10861 cacatggagc atgcatagcg aataagtatc agcacgatcc tggaatgtta atttcgtaaa
    10921 taccgtctag gacataatgc tgccaccaat agagcggctt gttgggccct gaactatgga
    10981 acatggattc actgcaatta tgtttttccc aagcacaaat catatttcat cgagtagtta
    11041 ttttccacga ttaaccactg tttcctccct gcatagatac agttcattat taatgataat
    11101 acacagtaag atacgggccc ttgctcctag cgtacgaaaa agacaaccac gcctggtgat
    11161 gcgtggtctc gtccaggttc tccccagcac taggatccca gtcagtttca actgcactcc
    11221 tgagtctttt agcccacttg aaggtaagga taaacttaca agtagttctg caagttcgca
    11281 gcatagacag ctgcttgatc tgacatgtca tgacgttcaa agaaatccgt cagcacagcc
    11341 gcgatcttgg tatccggtat cccggaaata gggaagtaga atttggggat cggggcgcga
    11401 cggccaggat ggatctcgta attgagcatc aaaggcaagt acgtgggggg atcaccgggc
    11461 tgcgagggcc gggtgggata agcgcgaggg ccctccacaa tatctagagc gcgccagagc
    11521 tcctctagca ttgacaggcc ctcggtgata tctggatcct ccttcgccag ccggtcaccc
    11581 attgtccagt gctcgatgac acggtcgaag cggacgtcga attcggctag gtagaacttc
    11641 agacgtgtgc ggtgcgggtc gaccaggtcg caggacacga ggaaaatgtc cgtcttttgt
    11701 gacggttgtt gcaggtattc ttggagggcg tcgcatccct gcgcgaagag ttgctcggag
    11761 tcgatggtgc ggatggcatc caggcatagc tgtgtcgcgg actgagctgt gacttgggcc
    11821 ttgagtgttg ggtagaagta ctccttgacg gagattccgg ctgggtccag gtcgagggca
    11881 agaattgtct gtgtcttgaa gggtagtttt gcgatttcgg tgggaggtag gcgtgcaaca
    11941 tcgctgtcgc tgagggtcag acgctcgagg agggcatggt gtaagtccaa gttgatcgcg
    12001 gcgccggtgg cctttaggtc gtgcagagcg cagggtagca gggcgcggtt gaacggatct
    12061 tgacctgtag tggccctgtg gctggtcggc tcgaatgcaa tgcgcgtggt tgaacggctc
    12121 ttggtgaaat tctgactcag ttcaaagggc ccagtgcttc ctaggatgca ttgaaagagc
    12181 tcgcggccag ggctagggaa ggggcccaac gaaggaacga ttaggtgggc gaagaggcag
    12241 agatactcat actgtcggtg cacactgtaa ttaccgtcga atagtagctt tcccagcatg
    12301 gggccatggt ggtgccagta ctggtgttca tctaaattcg agaagcgcag ggatttactg
    12361 agatgaagat agggcttagc tccagccccg ccttccttaa catcttttgt cgtcgatgag
    12421 cccgtcatga tagtggtgta ttgagaagga cttgggaaat ttgcaatccc aacatgaact
    12481 cacttcccaa tgacaaatat ccaggtagcc catgacagag cggcacaatt atcaatgcgc
    12541 tgccggcca
//
