BGC0002226: acu-dioxomorpholine B biosynthetic gene cluster from Aspergillus aculeatus ATCC 16872
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Location: 92,151 - 104,699 nt. (total: 12,549 nt).
This entry is originally from NCBI GenBank KV878985.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002226
Short description acu-dioxomorpholine B biosynthetic gene cluster from Aspergillus aculeatus ATCC 16872
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
KV878985.1
92151 - 104699
via Heterologous expression
Compounds
  • acu-dioxomorpholine B
  • acu-dioxomorpholine A
Species Aspergillus aculeatus ATCC 16872 [taxonomy]
References
Chemical products information
acu-dioxomorpholine B Evidence:
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Chemical database entries
NPAtlas
acu-dioxomorpholine A Evidence:
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List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ASPACDRAFT_46595
  • OJJ96433.1
 92289 - 100350 (-) hypothetical protein
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    • ASPACDRAFT_46596
    • OJJ96434.1
    		 100949 - 102359 (+) hypothetical protein
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      • ASPACDRAFT_1890851
      • OJJ96435.1
      		 103240 - 104578 (-) hypothetical protein
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        Biosynthesis information

        Biosynthetic modules

        Name
        Unk01
        Type
        nrps-type1
        Genes
        ASPACDRAFT_46595
        Substrates
        tryptophan (evidence: Structure-based inference [1])
        Integrated Monomers
        Domains
        adenylation
        Name
        Unk02
        Type
        nrps-type1
        Genes
        ASPACDRAFT_46595
        Substrates
        D-phenyllactic acid (evidence: Structure-based inference [1])
        Integrated Monomers
        Domains
        adenylation
        Annotation changelog

        Entry version: 2

        Date
        Changes
        Submitters
        Reviewers
        2022-10-07
        Changed chemical structures for compounds: acu-dioxomorpholine B.
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
        2022-10-07
        Added NPAtlas links to compounds: acu-dioxomorpholine B.
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

        Entry version: 1

        Date
        Changes
        Submitters
        Reviewers
        2022-09-15
        Entry added
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
        2022-09-15
        Added NRP substrate specificities
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
        Detailed domain annotation
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