BGC0002227 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002227 (Aspergillus luchuensis IFO 4308)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	18,661	AKML B/AKML D/AKML A/AKML C	NRPS:Type I	100%

BGC0002227 - Region 1 - T1PKS

Download region GenBank file

Download region SVG

Location: 1 - 18,661 nt. (total: 18,661 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 18,662
Label		BGC0002227

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002227	1.00	NRP	AKML B, AKML D, AKML A, AKML C	Aspergillus luchuensis IFO 4308
BGC0002228	0.34	NRP	CIML B, CIML A, CIML D, CIML C	Colletotrichum incanum
BGC0001913	0.29	Polyketide	phomoidride	fungal sp. ATCC 74256
BGC0001340	0.28	Polyketide	byssochlamic acid	Byssochlamys fulva
BGC0002266	0.26	Terpene, Polyketide	calidoustene A, calidoustene B, calidoustene C	Aspergillus calidoustus
BGC0001124	0.26	Polyketide	pyranonigrin E	Aspergillus niger ATCC 1015
BGC0002180	0.25	Polyketide	(+)-asperlin, (2Z,4Z,6E)-octa-2,4,6-trienoic acid	Aspergillus nidulans FGSC A4
BGC0002211	0.24	Polyketide	HEx-pks1 polyketide	Paraphaeosphaeria sporulosa
BGC0001749	0.24	Polyketide	epipyriculol	Pyricularia oryzae 70-15
BGC0002729	0.24	Polyketide	sordarial	Neurospora crassa OR74A

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002227	1.00	NRP	AKML B, AKML D, AKML A, AKML C	Aspergillus luchuensis IFO 4308
BGC0002228	0.67	NRP	CIML B, CIML A, CIML D, CIML C	Colletotrichum incanum
BGC0001913	0.63	Polyketide	phomoidride	fungal sp. ATCC 74256
BGC0001340	0.62	Polyketide	byssochlamic acid	Byssochlamys fulva
BGC0002266	0.60	Terpene, Polyketide	calidoustene A, calidoustene B, calidoustene C	Aspergillus calidoustus
BGC0001124	0.60	Polyketide	pyranonigrin E	Aspergillus niger ATCC 1015
BGC0002180	0.58	Polyketide	(+)-asperlin, (2Z,4Z,6E)-octa-2,4,6-trienoic acid	Aspergillus nidulans FGSC A4
BGC0002211	0.58	Polyketide	HEx-pks1 polyketide	Paraphaeosphaeria sporulosa
BGC0001749	0.58	Polyketide	epipyriculol	Pyricularia oryzae 70-15
BGC0002729	0.57	Polyketide	sordarial	Neurospora crassa OR74A

Similar known gene clusters from MIBiG 4.0

Module view

Legend

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 18661:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

AKAW_03689

PKS_AT (574..879): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Methylmalonyl-CoA: 70.8%; 2-Methylbutyryl-CoA: 62.5%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 63.1
Methoxymalonyl-CoA: 55.8
Malonyl-CoA: 40.7
Propionyl-CoA: 27.9
Isobutyryl-CoA: 19.1
Benzoyl-CoA: 15.2
Ethylmalonyl-CoA: 14.6
CHC-CoA: 11.3
fatty_acid: 10.9
2-Methylbutyryl-CoA: 9.7
3-Methylbutyryl-CoA: 9.4
trans-1,2-CPDA: 0.0
inactive: 0.0
Acetyl-CoA: 0.0