BGC0002228 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002228 (Colletotrichum incanum)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	T1PKS	1	22,490	High	CIML B/CIML A/CIML D/CIML C	NRPS:Type I

BGC0002228 - Region 1 - T1PKS

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Location: 1 - 22,490 nt. (total: 22,490 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

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Gene details

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Gene overview

MIBiG

Tailoring

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

NRPS/PKS domains

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 22,491
Label		BGC0002228

Tailoring functions

Oxidoreductases: oxygenase

CI238_12749: cytochrome P450

smcogs: SMCOG1034: cytochrome P450

Ligases: synthase

CI238_12752: Beta-ketoacyl synthase

smcogs: SMCOG1093: Beta-ketoacyl synthase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002228.3	1.00	NRPS	CIML B, CIML A, CIML D, CIML C	Colletotrichum incanum
BGC0002227.3	0.69	NRPS	AKML B, AKML D, AKML A, AKML C	Aspergillus luchuensis IFO 4308
BGC0002191.2	0.67	PKS	prolipyrone B, gibepyrone D	Fusarium graminearum PH-1
BGC0001284.4	0.66	PKS	alternariol	Parastagonospora nodorum SN15
BGC0001273.3	0.66	PKS	asperlactone	Aspergillus ochraceus
BGC0001275.3	0.66	PKS	6-methylsalicyclic acid	Glarea lozoyensis
BGC0002211.3	0.65	PKS	HEx-pks1 polyketide	Paraphaeosphaeria sporulosa
BGC0001164.3	0.65	PKS	1-heptadecene	Cyanothece sp. PCC 7822
BGC0001160.5	0.65	PKS	1-nonadecene, (14Z)-1,14-nonadecadiene	Synechococcus sp. PCC 7002
BGC0002192.3	0.64	PKS	FR901512	fungal sp. No.14919

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002228.3	1.00	NRPS	CIML B, CIML A, CIML D, CIML C	Colletotrichum incanum
BGC0002227.3	0.69	NRPS	AKML B, AKML D, AKML A, AKML C	Aspergillus luchuensis IFO 4308
BGC0002191.2	0.67	PKS	prolipyrone B, gibepyrone D	Fusarium graminearum PH-1
BGC0001284.4	0.66	PKS	alternariol	Parastagonospora nodorum SN15
BGC0001273.3	0.66	PKS	asperlactone	Aspergillus ochraceus
BGC0001275.3	0.66	PKS	6-methylsalicyclic acid	Glarea lozoyensis
BGC0002211.3	0.65	PKS	HEx-pks1 polyketide	Paraphaeosphaeria sporulosa
BGC0001164.3	0.65	PKS	1-heptadecene	Cyanothece sp. PCC 7822
BGC0001160.5	0.65	PKS	1-nonadecene, (14Z)-1,14-nonadecadiene	Synechococcus sp. PCC 7002
BGC0002192.3	0.64	PKS	FR901512	fungal sp. No.14919

Similar known clusters from MIBiG 4.0

Module view

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Detailed domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 22490:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

CI238_12752: pk

PKS_AT (596..905): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Methylmalonyl-CoA: 66.7%; Ethylmalonyl-CoA: 62.5%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 65.0
Methoxymalonyl-CoA: 53.4
Malonyl-CoA: 39.9
Propionyl-CoA: 27.0
Benzoyl-CoA: 25.7
CHC-CoA: 24.0
trans-1,2-CPDA: 21.2
fatty_acid: 21.0
2-Methylbutyryl-CoA: 20.2
Ethylmalonyl-CoA: 16.2
Isobutyryl-CoA: 16.0
3-Methylbutyryl-CoA: 8.2
inactive: 0.0
Acetyl-CoA: 0.0

Link to PARAS substrate predictor