BGC0002228 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002228 (Colletotrichum incanum)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	18,237	CIML B/CIML A/CIML D/CIML C	NRPS:Type I	100%

BGC0002228 - Region 1 - T1PKS

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Location: 1 - 18,237 nt. (total: 18,237 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 18,238
Label		BGC0002228

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002228	1.00	NRP	CIML B, CIML A, CIML D, CIML C	Colletotrichum incanum
BGC0002227	0.37	NRP	AKML B, AKML D, AKML A, AKML C	Aspergillus luchuensis IFO 4308
BGC0002211	0.32	Polyketide	HEx-pks1 polyketide	Paraphaeosphaeria sporulosa
BGC0001124	0.28	Polyketide	pyranonigrin E	Aspergillus niger ATCC 1015
BGC0002180	0.27	Polyketide	(+)-asperlin, (2Z,4Z,6E)-octa-2,4,6-trienoic acid	Aspergillus nidulans FGSC A4
BGC0002729	0.27	Polyketide	sordarial	Neurospora crassa OR74A
BGC0001913	0.26	Polyketide	phomoidride	fungal sp. ATCC 74256
BGC0000046	0.26	Polyketide	depudecin	Alternaria brassicicola
BGC0001141	0.26	Polyketide	4-epi-15-epi-brefeldin A	Penicillium brefeldianum
BGC0001749	0.26	Polyketide	epipyriculol	Pyricularia oryzae 70-15

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002228	1.00	NRP	CIML B, CIML A, CIML D, CIML C	Colletotrichum incanum
BGC0002227	0.69	NRP	AKML B, AKML D, AKML A, AKML C	Aspergillus luchuensis IFO 4308
BGC0002211	0.65	Polyketide	HEx-pks1 polyketide	Paraphaeosphaeria sporulosa
BGC0001124	0.62	Polyketide	pyranonigrin E	Aspergillus niger ATCC 1015
BGC0002180	0.60	Polyketide	(+)-asperlin, (2Z,4Z,6E)-octa-2,4,6-trienoic acid	Aspergillus nidulans FGSC A4
BGC0002729	0.60	Polyketide	sordarial	Neurospora crassa OR74A
BGC0001913	0.60	Polyketide	phomoidride	fungal sp. ATCC 74256
BGC0000046	0.60	Polyketide	depudecin	Alternaria brassicicola
BGC0001141	0.60	Polyketide	4-epi-15-epi-brefeldin A	Penicillium brefeldianum
BGC0001749	0.59	Polyketide	epipyriculol	Pyricularia oryzae 70-15

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 18237:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

CI238_12752

PKS_AT (596..905): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Methylmalonyl-CoA: 66.7%; Ethylmalonyl-CoA: 62.5%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 65.0
Methoxymalonyl-CoA: 53.4
Malonyl-CoA: 39.9
Propionyl-CoA: 27.0
Benzoyl-CoA: 25.7
CHC-CoA: 24.0
trans-1,2-CPDA: 21.2
fatty_acid: 21.0
2-Methylbutyryl-CoA: 20.2
Ethylmalonyl-CoA: 16.2
Isobutyryl-CoA: 16.0
3-Methylbutyryl-CoA: 8.2
inactive: 0.0
Acetyl-CoA: 0.0