BGC0002232: ergotamine biosynthetic gene cluster from Claviceps purpurea 20.1
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 234,064 - 290,014 nt. (total: 55,951 nt).
This entry is originally from NCBI GenBank CAGA01000020.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002232
Short description ergotamine biosynthetic gene cluster from Claviceps purpurea 20.1
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • other (other)
Loci
CAGA01000020.1
234064 - 290014
via
Compounds
  • ergotamine
Species Claviceps purpurea 20.1 [taxonomy]
References
Chemical products information
ergotamine Evidence: NMR [1], [2]
Copy SMILES
C33H35N5O5
Chemical database entries
ChEBI
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • CPUR_04073
  • CCE30225.1
 235117 - 246051 (-) non-ribosomal peptide synthetase
    copy AA seq
    copy Nt seq
    • CPUR_04074
    • CCE30226.1
    		 249862 - 260793 (-) non-ribosomal peptide synthetase
      copy AA seq
      copy Nt seq
      • CPUR_04075
      • CCE30227.1
      		 261607 - 262551 (+) uncharacterized protein
        copy AA seq
        copy Nt seq
        • CPUR_04076
        • CCE30228.1
        		 263944 - 265409 (-) uncharacterized protein
          copy AA seq
          copy Nt seq
          • CPUR_04077
          • CCE30229.1
          		 266067 - 267145 (+) uncharacterized protein
            copy AA seq
            copy Nt seq
            • CPUR_04078
            • CCE30230.1
            		 267505 - 268654 (-) uncharacterized protein
              copy AA seq
              copy Nt seq
              • CPUR_04079
              • CCE30231.1
              		 269008 - 270510 (-) probable isoamyl alcohol oxidase
                copy AA seq
                copy Nt seq
                • CPUR_04080
                • CCE30232.1
                		 271319 - 272167 (+) related to D-arabinitol 2-dehydrogenase
                  copy AA seq
                  copy Nt seq
                  • CPUR_04081
                  • CCE30233.1
                  		 272896 - 274403 (+) probable catalase isozyme P
                    copy AA seq
                    copy Nt seq
                    • CPUR_04082
                    • CCE30234.1
                    		 275063 - 277174 (+) related to trichodiene oxygenase cytochrome P450
                      copy AA seq
                      copy Nt seq
                      • CPUR_04083
                      • CCE30235.1
                      		 277495 - 281470 (-) related to non-ribosomal peptide synthetase
                        copy AA seq
                        copy Nt seq
                        • CPUR_04084
                        • CCE30236.1
                        		 282015 - 283157 (+) probable NADPH2 dehydrogenase chain OYE2
                          copy AA seq
                          copy Nt seq
                          • CPUR_04085
                          • CCE30237.1
                          		 284234 - 289659 (+) related to AM-toxin synthetase (AMT)
                            copy AA seq
                            copy Nt seq
                            Biosynthesis information
                            Annotation changelog

                            Entry version: next

                            Date
                            Changes
                            Submitters
                            Reviewers
                            2024-04-23
                            MIBiG v4 annotathon
                            • (ID: WGYEEFADVXA7X4KRF2R4CDK4)
                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                            Entry version: 1

                            Date
                            Changes
                            Submitters
                            Reviewers
                            2022-09-15
                            Entry added
                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                            Similar known gene clusters from MIBiG 4.0
                            Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
                            Click on reference genes to show details of similarities to genes within the current region.
                            Click on an accession to open that entry in the MiBIG database.