BGC0002233 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002233 (Trichoderma virens Gv29-8)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	31,758	trichoxide	PKS	100%

BGC0002233 - Region 1 - T1PKS

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Location: 1 - 31,758 nt. (total: 31,758 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 31,759
Label		BGC0002233

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002233	0.92	Polyketide	trichoxide	Trichoderma virens Gv29-8
BGC0002234	0.34	Polyketide	flavoglaucin	Aspergillus ruber CBS 135680
BGC0001264	0.30	Polyketide	betaenone A, betaenone B, betaenone C	Phoma betae
BGC0001124	0.28	Polyketide	pyranonigrin E	Aspergillus niger ATCC 1015
BGC0002211	0.27	Polyketide	HEx-pks1 polyketide	Paraphaeosphaeria sporulosa
BGC0000046	0.27	Polyketide	depudecin	Alternaria brassicicola
BGC0002228	0.27	NRP	CIML B, CIML A, CIML D, CIML C	Colletotrichum incanum
BGC0001141	0.27	Polyketide	4-epi-15-epi-brefeldin A	Penicillium brefeldianum
BGC0002731	0.26	Polyketide	nanangenine A, nanangenine B, nanangenine C	Aspergillus nanangensis
BGC0001504	0.25	Polyketide	amycomicin	Amycolatopsis sp. AA4

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002233	1.00	Polyketide	trichoxide	Trichoderma virens Gv29-8
BGC0002234	0.68	Polyketide	flavoglaucin	Aspergillus ruber CBS 135680
BGC0001264	0.63	Polyketide	betaenone A, betaenone B, betaenone C	Phoma betae
BGC0001124	0.62	Polyketide	pyranonigrin E	Aspergillus niger ATCC 1015
BGC0002211	0.61	Polyketide	HEx-pks1 polyketide	Paraphaeosphaeria sporulosa
BGC0000046	0.61	Polyketide	depudecin	Alternaria brassicicola
BGC0002228	0.60	NRP	CIML B, CIML A, CIML D, CIML C	Colletotrichum incanum
BGC0001141	0.60	Polyketide	4-epi-15-epi-brefeldin A	Penicillium brefeldianum
BGC0002731	0.60	Polyketide	nanangenine A, nanangenine B, nanangenine C	Aspergillus nanangensis
BGC0001067	0.59	Polyketide, Terpene	fumagillin, β-trans-bergamotene, fumagillol	Aspergillus fumigatus Af293

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 3734 - 31758:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Me-redmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

TRIVIDRAFT_47407

PKS_AT (534..850): mmal

ATSignature: Malonyl-CoA, Ethylmalonyl-CoA, Methylmalonyl-CoA

Top 3 matches:: Malonyl-CoA: 62.5%; Ethylmalonyl-CoA: 62.5%; Methylmalonyl-CoA: 62.5%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 72.5
Methoxymalonyl-CoA: 70.5
Malonyl-CoA: 53.4
Ethylmalonyl-CoA: 41.9
Propionyl-CoA: 31.8
Isobutyryl-CoA: 22.9
trans-1,2-CPDA: 20.8
fatty_acid: 15.3
CHC-CoA: 14.5
Acetyl-CoA: 12.9
2-Methylbutyryl-CoA: 10.7
inactive: 0.0
Benzoyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0