BGC0002237 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002237 (Aspergillus oryzae RIB40)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	23,559	dichlorodiaporthin	PKS	100%

BGC0002237 - Region 1 - T1PKS

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Location: 1 - 23,559 nt. (total: 23,559 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 23,560
Label		BGC0002237

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002237	1.00	Polyketide	dichlorodiaporthin	Aspergillus oryzae RIB40
BGC0000013	0.60	Polyketide	alternariol	Aspergillus nidulans FGSC A4
BGC0002236	0.34	Polyketide	8-methyldiaporthin	Aspergillus oryzae RIB40
BGC0002253	0.33	Polyketide	waikikiamide A, waikikiamide B, waikikiamide C, (+)-semivioxanthin, semivioxanthin	Aspergillus sp. FM242
BGC0002596	0.32	Polyketide	lecanoric acid, orsellinic acid	Claviceps purpurea 20.1
BGC0000161	0.30	Polyketide	isoterrein	Aspergillus terreus NIH2624
BGC0000048	0.25	Polyketide	dothistromin	Dothistroma septosporum
BGC0001284	0.22	Polyketide	alternariol	Parastagonospora nodorum SN15
BGC0001264	0.22	Polyketide	betaenone A, betaenone B, betaenone C	Phoma betae
BGC0001906	0.22	Polyketide	naphthalene	Daldinia eschscholzii IFB-TL01

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002237	1.00	Polyketide	dichlorodiaporthin	Aspergillus oryzae RIB40
BGC0000013	0.84	Polyketide	alternariol	Aspergillus nidulans FGSC A4
BGC0002236	0.67	Polyketide	8-methyldiaporthin	Aspergillus oryzae RIB40
BGC0002253	0.66	Polyketide	waikikiamide A, waikikiamide B, waikikiamide C, (+)-semivioxanthin, semivioxanthin	Aspergillus sp. FM242
BGC0002596	0.65	Polyketide	lecanoric acid, orsellinic acid	Claviceps purpurea 20.1
BGC0000161	0.64	Polyketide	isoterrein	Aspergillus terreus NIH2624
BGC0000048	0.58	Polyketide	dothistromin	Dothistroma septosporum
BGC0001284	0.55	Polyketide	alternariol	Parastagonospora nodorum SN15
BGC0001264	0.55	Polyketide	betaenone A, betaenone B, betaenone C	Phoma betae
BGC0001906	0.55	Polyketide	naphthalene	Daldinia eschscholzii IFB-TL01

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 23559:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

AO090701000530

PKS_AT (969..1308): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 91.7%; inactive: 58.3%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 109.3
Methylmalonyl-CoA: 56.2
inactive: 55.6
Methoxymalonyl-CoA: 54.8
Propionyl-CoA: 40.8
Isobutyryl-CoA: 23.9
Acetyl-CoA: 21.7
Benzoyl-CoA: 18.5
2-Methylbutyryl-CoA: 18.4
Ethylmalonyl-CoA: 14.2
3-Methylbutyryl-CoA: 13.6
CHC-CoA: 13.4
fatty_acid: 13.2
trans-1,2-CPDA: 8.2