LOCUS       BGC0002239             32747 bp    DNA     linear   PLN 05-JUL-2021
DEFINITION  Acremonium sp. pyd gene cluster, complete sequence.
ACCESSION   BGC0002239
VERSION     BGC0002239
KEYWORDS    .
SOURCE      Acremonium sp
  ORGANISM  Acremonium sp.
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Sordariomycetes; Hypocreomycetidae; Hypocreales; Hypocreales
            incertae sedis; Acremonium.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 17:11:32
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 32747
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..32747
                     /db_xref="taxon:2046025"
                     /mol_type="genomic DNA"
                     /organism="Acremonium sp."
     protocluster    1..32747
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[7582:21059]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      7583..21059
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     protocluster    1..32747
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[7582:21059]"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      7583..21059
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
     cand_cluster    1..32747
                     /SMILES="C([*])C(-O)(C)NC(Cc1ccc(O)cc1)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="chemical_hybrid"
                     /product="T1PKS"
                     /product="NRPS"
                     /protoclusters="2"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..32747
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0002239"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..32747
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(<1104..>2384)
                     /gene="pydG"
     mRNA            complement(<1104..>2384)
                     /gene="pydG"
                     /product="PydG"
     CDS             complement(1104..2384)
                     /codon_start=1
                     /gene="pydG"
                     /note="alpha/beta hydrolase"
                     /product="PydG"
                     /protein_id="QXF14596.1"
                     /transl_table=11
                     /translation="MFTFSSSFMFDFELTRLLGSASSGGCDVGEFKSAVGKIKKDDPES
                     WSVAWKEQAERAQRIGDQAAKAGYRLLARNAYLRASNYFRVTPYMFSNDDARVVPLIEQ
                     SISSFKKAAVLMDGEVICVEIPYEKGITLPGYLFLPPSYARLPGKVPIVMYAAGADSTK
                     EELYFLYGHTGPQLGYAVLCLEGPGQGLLLKKSKVPLRPDFEVVAEKIVEFLDNLSESR
                     PTLELDTGRLAMAGAATGGYFALRAATNPRVKACISIDPFFSLWELCLSRAPKAFFKLW
                     DSGWVPDSTFDTFTDVHGRGNFQSGWEINLGRSSMGAEKPTAMFRRFKDFTLEPAAGEV
                     PILDKIRCAVFLTGPGAGQDMYSSAEESTFKIHRLLSNVPDSNKEVWVPTDVAEGGLTA
                     KIGAWALLAQKTFEFLDKHFDIKRPEL"
     misc_feature    1104..31038
                     /note="pyd gene cluster"
     gene            <4625..>5944
                     /gene="pydF"
     mRNA            <4625..>5944
                     /gene="pydF"
                     /product="PydF"
     CDS             4625..5944
                     /codon_start=1
                     /gene="pydF"
                     /note="transcriptional factor"
                     /product="PydF"
                     /protein_id="QXF14597.1"
                     /transl_table=11
                     /translation="MGRPQRADKQRRETDGPQKSRPSLTQAQKNSTTIRIHSDDHDQGR
                     PNTNGYARQEQHAWEDASLHSLDFRLCHSSNLEDDEMHGTATDDMIPVNFDFVSPQVPH
                     AMSDLGMYDFGSEATASDLLDPEPCAQFISLASHSAADHVEKATAERPGNDGSSSPSSS
                     LLRTSSSPSQQAVEKLSDLNVQIHRQLTTDHGSLDSAGRRTQLSCAVVSMIEGLKTFRE
                     LLFDILSTTSRSPLQAAFRDGQNNGTSRPNTAASQNMQQHRRSGSMLSLSDCDAVSLSN
                     SNSDSRPFQEGSHHFGCLDMSTSLLLLSCYANLILLCREVFAAIRRALPISGHQSTLLE
                     LSGFRIGSVAVQEDSDLQITILIQVVVRLIDGIGHCLGYPYSSTTERGEASPSDRGISL
                     ELLDLVLGPKGRQGQPSHIGQIEALREDIRNLSKIVYKSI"
     gene            complement(<6446..>6820)
                     /gene="pydZ"
     mRNA            complement(<6446..>6820)
                     /gene="pydZ"
                     /product="PydZ"
     CDS             complement(6446..6820)
                     /codon_start=1
                     /gene="pydZ"
                     /note="hypothetical protein"
                     /product="PydZ"
                     /protein_id="QXF14599.1"
                     /transl_table=11
                     /translation="MSSAHVLSDWLSYSIAGFSALCVQAHLTSRFTPAFSRNLSEKLPE
                     HNRAVFWWAGMSTRALRYVFVVINITITALLLSEELRSFGLKFSLVLLGVGFYSDMKLG
                     ESPVPHMILCSVVGAAILVR"
     gene            complement(<7583..>21059)
                     /gene="pydA"
     mRNA            complement(join(<7583..8108,8504..11456,11537..13348,
                     13419..14125,14192..16466,16566..16786,16878..19960,
                     20052..>21059))
                     /gene="pydA"
                     /product="PydA"
     CDS             complement(join(7583..8108,8504..11456,11537..13348,
                     13419..14125,14192..16466,16566..16786,16878..19960,
                     20052..21059))
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (16-451). E-value:
                     1.1e-167. Score: 550.1. Matches aSDomain:
                     nrpspksdomains_pydA_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (564-880). E-value: 2.6e-90.
                     Score: 294.6. Matches aSDomain:
                     nrpspksdomains_pydA_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (952-1128). E-value: 3.6e-24.
                     Score: 77.9. Matches aSDomain:
                     nrpspksdomains_pydA_PKS_DH.1"
                     /NRPS_PKS="Domain: cMT (1390-1593). E-value: 2e-71. Score:
                     232.2. Matches aSDomain: nrpspksdomains_pydA_cMT.1"
                     /NRPS_PKS="Domain: PKS_KR (2140-2313). E-value: 1.8e-47.
                     Score: 153.5. Matches aSDomain:
                     nrpspksdomains_pydA_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (2429-2503). E-value: 7.4e-09.
                     Score: 27.7. Matches aSDomain:
                     nrpspksdomains_pydA_PKS_PP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (2592-2884). E-value:
                     1.9e-65. Score: 212.7. Matches aSDomain:
                     nrpspksdomains_pydA_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (3055-3467). E-value:
                     9.7e-94. Score: 306.1. Matches aSDomain:
                     nrpspksdomains_pydA_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (3585-3658). E-value: 7.9e-13.
                     Score: 40.3. Matches aSDomain: nrpspksdomains_pydA_PCP.1"
                     /NRPS_PKS="Domain: TD (3698-3924). E-value: 2.3e-59. Score:
                     192.4. Matches aSDomain: nrpspksdomains_pydA_TD.1"
                     /codon_start=1
                     /gene="pydA"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     itr_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 219.1; E-value:
                     1.7e-66)"
                     /gene_kind="biosynthetic"
                     /note="PKS-NRPS"
                     /product="PydA"
                     /protein_id="QXF14600.1"
                     /sec_met_domain="itr_KS (E-value: 7.9e-175, bitscore:
                     571.0, seeds: 96, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 4.7e-91, bitscore: 294.6,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 4.2e-42, bitscore:
                     133.5, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 1.8e-52, bitscore:
                     167.6, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2.8e-93, bitscore:
                     302.1, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 7e-13, bitscore:
                     38.4, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 2e-43, bitscore:
                     137.7, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAERDTESIAGGREPIAVVGSGMRFPGSSSSPSKLWKLLLKPRD
                     LLSRIPENRFNADSFYHPNSSHHGTTDVQESYFLEEDHRHFDAAFFNIKPVEAHAIDPQ
                     QRVLMEVVYESLEASGMTMESLAGSPTGVYVGLMCADYAELVNSDVNALPTYTPTGNAR
                     SIMSNRISYFFDWHGPSMTIDTACSSSLVAVHEAVQLLRSGDSDVAIAAGSNLMLAPLQ
                     YIAASKLKMLSADSRSRMWDANASGYARGEGVAAVVLKRLSSAIADGDHIECIIRETAI
                     NQDGRTKGITMPSSKAQADLIAKTYAKAGLDPRNPDQRCQYFEAHGTGTAAGDPKEAEA
                     ISKAFFHPGEVVSGASDPLYVGSIKTVIGHTEGTAGLAGLLRASLAVQHGTIPPNMLFD
                     SLHPNVEPFYTNLKIATEPTAWPKLAEGTSRRCSINSFGFGGTNAHAIVENYVPPAPVQ
                     VSQASPGRQFTPFTFSAASERSLRGVLADYAEHLRLHPDISLHDLAYTLHARRSGHAVR
                     THVSADSVADLHTKIDGLLRAPTSSDGGSRNLGLRSRPWSSPLRALGVFTGQGAQWATM
                     GRELVLHSQYCRDLVRDVDRMLQLLPEAERPDWSVMDQVTCDAPLSRIDSAVISQPLCT
                     VVQIMLFDLLTSAGVRFQAVVGHSSGEIAAAYAAGYLTRDDAVKVAYYRGYFTSLTPSD
                     RPGAMMAVGTSAEDANELCNLSMFKGRLAVAAINSSSSVTISGDRDAVEQAKEVLEDEK
                     KFARILKVDKAYHSHHMLPCAEEYLRALERSGINPLQGRDDCVWHSSTYENRHVHGARD
                     LAGQYWADNMVRPVLFSHCVDAAAAGSEARFDFAVELGPHPTLKGPALQTIQEAHKVTV
                     PYTGLLQRGKDDVQAFSDALGYLWSQFSPSIVDLGAFDTLVSGIKSRKMLQDLPAYHWD
                     HDNIFWHKSRPTKAFLTQKSIPHPLLGTRTTDVMDEQIRWRNHLLLNELPWIRGHQLQG
                     QVIYPATAYLSTAIEAAMFLVPEGASAQLVEVRDFNLGKPLIFGEDGSGIETVFTLSDI
                     TKGEDKTYSASFTYHACSNADAEQLSTHATGRVIVITGEASAGLLPSQSKDLPNLVDIP
                     EDRFYKSLETVGYGYSGDFRAMSSIQRKLNFSSSRVRVPLQEDDRVKLMLHPAMLDTAL
                     QGIFLAYCWPGDGSLDQLHVPTGIQSCRVNAGLCRQQLESATEVTSSSQLTGNPLVTKN
                     LNGNVEISTEDGSCLVQMEGLKVVSFSEPTAEADRAVFTEYVWDVLAPDAERAMQGKRA
                     TAEDYELAFAIERVSVYYMRQLASLFPEETRSSLNLEWHFVCLFNFITHVLSTTGAGQR
                     KTAKKEWLQDSAADIERIKERYADTVDMRLARAVGDNLPAVIRGETTMLEHITKDNLLD
                     RFYEVGLGLKEFSGYVGKTVEQVVHRHPHMKMLEIGAGTGGATKVIMGGIGRAFSSYTY
                     TDISPNFFETASEVFSSVADKMIFKTLDVEKDIVQQGYEEHSYDLVVASLVLHATKNLK
                     QTLANTRRLLRPGGYLVIQEVCNNEPSRTGFMMCALPGWWLGQDDGRKLSPCVSTPEWN
                     DLLLQTGFSGVDSTTHELDSVPFQLAVIVSQAVDERVSLLREPLALVGTDSPVAEHWDL
                     VLVGGQSPKSSHLIEEIVGMLQSPNVSHTIVKTVDDIDSSTISETTAILFLEELDKPVF
                     KGITERTLEGLKRLFETQRTVLWVTQGSRSADPYMGMSVGLGRTLILENPDLVLQFLDL
                     EPGIEPEARTILEALLRLRQSDRWAKEGGTFEDVLWTNEHELAYINGELCLSRVHLAAP
                     LNDRFNASKRTVLEAMNPQSVPMNLSLGQTIAPGLVLNDHLASKMLGSPDAVESESETV
                     IRVSHSLLMPDLATIPPSYLVLGTNTGQNGRIVLAISETNGSYASVPPGRVLDVAPLQG
                     EEPLLLSRLHTQLQVDGMLSICEDGSVLAIHEPPVDLASAIVERGASLGIHVYITTAAS
                     PSDRSWTQVHSYSPRTVVKSLLPPDISVFIDCSTRSLSQRAGSLIASCLPETCLKTTSA
                     SLPSLRRIRGFSVADMIDNLKGALPRALEKLAAPESSTNTLPLIRADQLGPGSSDADLF
                     TPAIVAWNTTGKVPVQVSTVDSHTTFRSDRTYVFFGLTSDLAQSICDWMVTHGARNIVL
                     TSRHPNIDARWKRTLKEAGVRVEVFSNDITDKAALVSLVDHIRQNLPPIAGIAHGAMVL
                     NDVSFFEMTFEKMIQVIRPKVQGAIYLDELFQEPTLDFCIFFSSCTAIAGNRGQSAYTA
                     ANMFMSSLASQRREKGLAGSILHIGAVMGVGYINRGFKDYIFTALSRAGYMMVTEREFH
                     LCFGEAVLASHPKSGRNPDVVTALETSKFGDTLPLWAKFPRFQYCLAAADSGSLKQAQK
                     KHNAAVSTKLRLAEATTAEEALEIVQDSFYQKLQVVLQISPDTEKSQVLASGTDDLGID
                     SLVAVEIRSWFIKEIDTEIAVFKVLSGISIAELVEFAVENMPGELTPNMSDSLNAVPET
                     PTAPVIPASPPSGSVSSAPSSDPPKTTAETSQHLSESSSKTSQPDEKQSEERDSSTASL
                     EEPLETAYEKVLPVSPGQARFWFLKHLMEDQTTANNTILVSVQGQVRLDSLDAAVRRVG
                     ARHESLRTSFFVDKNQKAVQAISDSSRLYLQTKEIHSEAQVEAEFEALKNHAYDLINGE
                     CMQLIHLGMNATESYLLIGSHHIVMDGISLEVFLNDVQKAYNGQSLSSQVYQYSDYSEK
                     LRQELGNGAMQKEIEYWRSEFAEAPTPLPLLPFAAVKQRKALTAYRHTSVSRTVDAKVA
                     RQISDTCRKLKANVFHFYLGVFEVLLFKLFGKNDVCIGMADANRWDDQVAQSIGMYLNL
                     LPLRFRLDKQQSFETVLKDTRRKAYNAMSNSRLPFDALLDNLNCDRSTAFSPLFQAFIN
                     YRQGVRENRTLGSARGVTKKISLPRAGYDMSLDIIENPGGDTRLAFMLQDALYSEEETA
                     QVLELYCNLLSELSGSPGQILKDVSLFTRSDVDKAVQLGRGAALPSQGSETLVHRIDAM
                     IANPPQEIALRDHTGRSWTWEQLGQQVNRMASTLLQVNVTAGSVIAVHQEASPDLVFSL
                     LAILRVGGIYVPLDSNLPEARLRSIITECDPSVLLLDQTTLARAGDLALPPSVTVLDVS
                     SLPPRVKDAICPTTARRATDPAAILFTSGSTGVPKGVILSHGGLRNHVEALVHTHGFGR
                     ETVLQQSSVGFDMSLNQIFMSLANGGTLVLVPEPFRKDSAAVAKMILEQNITYTSATPS
                     EYLAWLRHGSNSLFQSTSWRFATAGGEQFTPQLLEAFQTLGTQFEHPFHAFNAYGPTEC
                     TLSSNEMKVSLEASSSARQITAGKALPNCSFYVVDDSLDPLPVGWPGEILIGGAGVALG
                     YLNNPAETARKFLVDPKASSSAMGQGWGRMYRTGDKGVLRPDGTLQILGRIEGDTQIKL
                     RGLRIEMQDVEKSILDASEGQISEVGVTPRGDPTILVAHVVLSRNASFSNKQQYLRDLS
                     ASLPLPQYMRPAAIIPIDCMPLTASGKVDRRALQGLELSSTRGQSHIQDQGAATQLTEA
                     ESELAQIWKDVLPQQLQEVHLIDGASDFFQVGGNSMLLIELRRLVASRLQVDIPLLRLF
                     ESSTLGAMAAVIQDLSTVAQVPEVGWEAETQVPSSWAQGDVQPAHLQSHSSPRTVVITG
                     ATGFLGKQLVRLLVANANIHRVHCIAVRNVEKLAEFAGSDKVSIHPGDLAQPRCGLSEA
                     DAVSIFRSTDAIIHNGADVSFLKSYSSLRAPNVLSTKELVKLSLPRLIPLHYVSTATVG
                     KLNRSDTLAPESLARFPPGATFSDGYAASKWASEVFLENATKKLGLPTFIHRPSSITGD
                     QAAENDIVPNLLKYSSLIKALPDTAKWSGYVDLISVERAAAGIIGSVLQDRPDLGTTAP
                     ETQFLHQTGEKVIPAQSIKAVLSPKDEPEWDSLAMAEWVSRAVQKGMNPLIGEFLLSVD
                     RGQGLSVGQKLLLKTDQAKKGMNFSTSERLQCRRDKTNPGRQVCDQGPSSVHPQPAFHR
                     GRDVSPRHPALDHPDPIQGRSHVPHVRETEQQTDGVPRHGARGSKLISTDEQIDDAESV
                     VDGVDHDEDPAPPQASRCPPSWEVGVCALAEGRLHPGSEDEVLVKSKGEYPCGSDGREE
                     AEEAEWQCDEGHGDGEPDD"
     gene            <7607..>8095
                     /gene="pydX"
     mRNA            <7607..>8095
                     /gene="pydX"
                     /product="PydX"
     CDS             7607..8095
                     /codon_start=1
                     /gene="pydX"
                     /note="hypothetical protein"
                     /product="PydX"
                     /protein_id="QXF14598.1"
                     /transl_table=11
                     /translation="MSLIALPLRLLRLLPAITSTWVLAFALDEHLIFGTWVQPSLRESA
                     NANLPAWWTTGGLRWRWILIVVYPINYALGVVNLFVGRDELRATGAMSWYTIGLLFSLA
                     HMGYMRTALDRIGMIERGVPRGNVTSSMESWLRMNRTRALVTDLPAWICFVTAALKAL"
     aSDomain        complement(8791..9468)
                     /aSDomain="TD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_pydA_TD.1"
                     /evalue="2.30E-59"
                     /label="pydA_TD.1"
                     /locus_tag="pydA"
                     /protein_end="3924"
                     /protein_start="3698"
                     /score="192.4"
                     /tool="antismash"
                     /translation="VVITGATGFLGKQLVRLLVANANIHRVHCIAVRNVEKLAEFAGSD
                     KVSIHPGDLAQPRCGLSEADAVSIFRSTDAIIHNGADVSFLKSYSSLRAPNVLSTKELV
                     KLSLPRLIPLHYVSTATVGKLNRSDTLAPESLARFPPGATFSDGYAASKWASEVFLENA
                     TKKLGLPTFIHRPSSITGDQAAENDIVPNLLKYSSLIKALPDTAKWSGYVDLISVERAA
                     AGII"
     aSModule        complement(8791..12866)
                     /complete
                     /domains="nrpspksdomains_pydA_Condensation_LCL.1"
                     /domains="nrpspksdomains_pydA_AMP-binding.1"
                     /domains="nrpspksdomains_pydA_PCP.1"
                     /domains="nrpspksdomains_pydA_TD.1"
                     /final_module
                     /locus_tags="pydA"
                     /monomer_pairings="Tyr -> Tyr"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(9406..9471)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_pydA_0017"
                     /evalue="2.00E-02"
                     /label="PKSI-KR_m1"
                     /locus_tag="pydA"
                     /protein_end="3719"
                     /protein_start="3697"
                     /score="7.6"
                     /tool="antismash"
                     /translation="TVVITGATGFLGKQLVRLLVAN"
     aSDomain        complement(9589..9807)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_pydA_PCP.1"
                     /evalue="7.90E-13"
                     /label="pydA_PCP.1"
                     /locus_tag="pydA"
                     /protein_end="3658"
                     /protein_start="3585"
                     /score="40.3"
                     /tool="antismash"
                     /translation="ESELAQIWKDVLPQQLQEVHLIDGASDFFQVGGNSMLLIELRRLV
                     ASRLQVDIPLLRLFESSTLGAMAAVIQD"
     CDS_motif       complement(10129..10179)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_pydA_0016"
                     /evalue="1.50E-04"
                     /label="NRPS-A_a8"
                     /locus_tag="pydA"
                     /protein_end="3478"
                     /protein_start="3461"
                     /score="14.5"
                     /tool="antismash"
                     /translation="DTQIKLRGLRIEMQDVE"
     aSDomain        complement(10162..11397)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_pydA_AMP-binding.1"
                     /evalue="9.70E-94"
                     /label="pydA_AMP-binding.1"
                     /locus_tag="pydA"
                     /protein_end="3467"
                     /protein_start="3055"
                     /score="306.1"
                     /specificity="substrate consensus: Tyr"
                     /tool="antismash"
                     /translation="ANPPQEIALRDHTGRSWTWEQLGQQVNRMASTLLQVNVTAGSVIA
                     VHQEASPDLVFSLLAILRVGGIYVPLDSNLPEARLRSIITECDPSVLLLDQTTLARAGD
                     LALPPSVTVLDVSSLPPRVKDAICPTTARRATDPAAILFTSGSTGVPKGVILSHGGLRN
                     HVEALVHTHGFGRETVLQQSSVGFDMSLNQIFMSLANGGTLVLVPEPFRKDSAAVAKMI
                     LEQNITYTSATPSEYLAWLRHGSNSLFQSTSWRFATAGGEQFTPQLLEAFQTLGTQFEH
                     PFHAFNAYGPTECTLSSNEMKVSLEASSSARQITAGKALPNCSFYVVDDSLDPLPVGWP
                     GEILIGGAGVALGYLNNPAETARKFLVDPKASSSAMGQGWGRMYRTGDKGVLRPDGTLQ
                     ILGRIEGDTQIKL"
     CDS_motif       complement(10303..10392)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_pydA_0015"
                     /evalue="9.80E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="pydA"
                     /protein_end="3420"
                     /protein_start="3390"
                     /score="43.5"
                     /tool="antismash"
                     /translation="PVGWPGEILIGGAGVALGYLNNPAETARKF"
     CDS_motif       complement(10924..10983)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_pydA_0014"
                     /evalue="2.00E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="pydA"
                     /protein_end="3213"
                     /protein_start="3193"
                     /score="23.4"
                     /tool="antismash"
                     /translation="AAILFTSGSTGVPKGVILSH"
     CDS_motif       complement(11182..11223)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_pydA_0013"
                     /evalue="1.40E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="pydA"
                     /protein_end="3127"
                     /protein_start="3113"
                     /score="12.2"
                     /tool="antismash"
                     /translation="LAILRVGGIYVPLD"
     CDS_motif       complement(11835..11951)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_pydA_0012"
                     /evalue="5.30E-08"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="pydA"
                     /protein_end="2936"
                     /protein_start="2897"
                     /score="25.1"
                     /tool="antismash"
                     /translation="RRKAYNAMSNSRLPFDALLDNLNCDRSTAFSPLFQAFIN"
     aSDomain        complement(11991..12866)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_pydA_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.90E-65"
                     /label="pydA_Condensation_LCL.1"
                     /locus_tag="pydA"
                     /protein_end="2884"
                     /protein_start="2592"
                     /score="212.7"
                     /tool="antismash"
                     /translation="VLPVSPGQARFWFLKHLMEDQTTANNTILVSVQGQVRLDSLDAAV
                     RRVGARHESLRTSFFVDKNQKAVQAISDSSRLYLQTKEIHSEAQVEAEFEALKNHAYDL
                     INGECMQLIHLGMNATESYLLIGSHHIVMDGISLEVFLNDVQKAYNGQSLSSQVYQYSD
                     YSEKLRQELGNGAMQKEIEYWRSEFAEAPTPLPLLPFAAVKQRKALTAYRHTSVSRTVD
                     AKVARQISDTCRKLKANVFHFYLGVFEVLLFKLFGKNDVCIGMADANRWDDQVAQSIGM
                     YLNLLPLRFRL"
     CDS_motif       complement(12000..12089)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_pydA_0011"
                     /evalue="5.00E-06"
                     /label="C5_LCL_267-296"
                     /locus_tag="pydA"
                     /protein_end="2881"
                     /protein_start="2851"
                     /score="19.0"
                     /tool="antismash"
                     /translation="DVCIGMADANRWDDQVAQSIGMYLNLLPLR"
     CDS_motif       complement(12420..12482)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_pydA_0010"
                     /evalue="1.40E-07"
                     /label="C3_LCL_132-143"
                     /locus_tag="pydA"
                     /protein_end="2741"
                     /protein_start="2720"
                     /score="24.1"
                     /tool="antismash"
                     /translation="HHIVMDGISLEVFLNDVQKAY"
     CDS_motif       complement(12687..12782)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_pydA_0009"
                     /evalue="5.90E-08"
                     /label="C2_DCL_024-062"
                     /locus_tag="pydA"
                     /protein_end="2652"
                     /protein_start="2620"
                     /score="25.0"
                     /tool="antismash"
                     /translation="LVSVQGQVRLDSLDAAVRRVGARHESLRTSFF"
     aSDomain        complement(join(13134..13348,13419..13425))
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_pydA_PKS_PP.1"
                     /evalue="7.40E-09"
                     /label="pydA_PKS_PP.1"
                     /locus_tag="pydA"
                     /protein_end="2503"
                     /protein_start="2429"
                     /score="27.7"
                     /tool="antismash"
                     /translation="VQDSFYQKLQVVLQISPDTEKSQVLASGTDDLGIDSLVAVEIRSW
                     FIKEIDTEIAVFKVLSGISIAELVEFAVE"
     aSModule        complement(13134..21011)
                     /complete
                     /domains="nrpspksdomains_pydA_PKS_KS.1"
                     /domains="nrpspksdomains_pydA_PKS_AT.1"
                     /domains="nrpspksdomains_pydA_PKS_DH.1"
                     /domains="nrpspksdomains_pydA_cMT.1"
                     /domains="nrpspksdomains_pydA_PKS_KR.1"
                     /domains="nrpspksdomains_pydA_PKS_PP.1"
                     /iterative
                     /locus_tags="pydA"
                     /monomer_pairings="pk -> Me-pk"
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(join(13774..14125,14192..14358))
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_pydA_PKS_KR.1"
                     /evalue="1.80E-47"
                     /label="pydA_PKS_KR.1"
                     /locus_tag="pydA"
                     /protein_end="2313"
                     /protein_start="2140"
                     /score="153.5"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="TYVFFGLTSDLAQSICDWMVTHGARNIVLTSRHPNIDARWKRTLK
                     EAGVRVEVFSNDITDKAALVSLVDHIRQNLPPIAGIAHGAMVLNDVSFFEMTFEKMIQV
                     IRPKVQGAIYLDELFQEPTLDFCIFFSSCTAIAGNRGQSAYTAANMFMSSLASQRREKG
                     LAGSILHIGA"
     CDS_motif       complement(13813..13923)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_pydA_0008"
                     /evalue="2.90E-17"
                     /label="PKSI-KR_m4"
                     /locus_tag="pydA"
                     /protein_end="2300"
                     /protein_start="2263"
                     /score="55.2"
                     /tool="antismash"
                     /translation="LDFCIFFSSCTAIAGNRGQSAYTAANMFMSSLASQRR"
     CDS_motif       complement(14263..14358)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_pydA_0007"
                     /evalue="1.60E-11"
                     /label="PKSI-KR_m1"
                     /locus_tag="pydA"
                     /protein_end="2172"
                     /protein_start="2140"
                     /score="36.8"
                     /tool="antismash"
                     /translation="TYVFFGLTSDLAQSICDWMVTHGARNIVLTSR"
     aSDomain        complement(join(16000..16466,16566..16707))
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_pydA_cMT.1"
                     /domain_subtypes="cMT"
                     /evalue="2.00E-71"
                     /label="pydA_cMT.1"
                     /locus_tag="pydA"
                     /protein_end="1593"
                     /protein_start="1390"
                     /score="232.2"
                     /tool="antismash"
                     /translation="MLEHITKDNLLDRFYEVGLGLKEFSGYVGKTVEQVVHRHPHMKML
                     EIGAGTGGATKVIMGGIGRAFSSYTYTDISPNFFETASEVFSSVADKMIFKTLDVEKDI
                     VQQGYEEHSYDLVVASLVLHATKNLKQTLANTRRLLRPGGYLVIQEVCNNEPSRTGFMM
                     CALPGWWLGQDDGRKLSPCVSTPEWNDLLLQTGFSGVDST"
     aSDomain        complement(17585..18112)
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_pydA_PKS_DH.1"
                     /evalue="3.60E-24"
                     /label="pydA_PKS_DH.1"
                     /locus_tag="pydA"
                     /protein_end="1128"
                     /protein_start="952"
                     /score="77.9"
                     /tool="antismash"
                     /translation="HPLLGTRTTDVMDEQIRWRNHLLLNELPWIRGHQLQGQVIYPATA
                     YLSTAIEAAMFLVPEGASAQLVEVRDFNLGKPLIFGEDGSGIETVFTLSDITKGEDKTY
                     SASFTYHACSNADAEQLSTHATGRVIVITGEASAGLLPSQSKDLPNLVDIPEDRFYKSL
                     ETVGYGYSGDFRA"
     CDS_motif       complement(17951..18028)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_pydA_0006"
                     /evalue="2.00E-10"
                     /label="PKSI-DH_m2"
                     /locus_tag="pydA"
                     /protein_end="1006"
                     /protein_start="980"
                     /score="33.1"
                     /tool="antismash"
                     /translation="WIRGHQLQGQVIYPATAYLSTAIEAA"
     aSDomain        complement(18329..19276)
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_pydA_PKS_AT.1"
                     /evalue="2.60E-90"
                     /label="pydA_PKS_AT.1"
                     /locus_tag="pydA"
                     /protein_end="880"
                     /protein_start="564"
                     /score="294.6"
                     /specificity="substrate consensus: pk"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="VFTGQGAQWATMGRELVLHSQYCRDLVRDVDRMLQLLPEAERPDW
                     SVMDQVTCDAPLSRIDSAVISQPLCTVVQIMLFDLLTSAGVRFQAVVGHSSGEIAAAYA
                     AGYLTRDDAVKVAYYRGYFTSLTPSDRPGAMMAVGTSAEDANELCNLSMFKGRLAVAAI
                     NSSSSVTISGDRDAVEQAKEVLEDEKKFARILKVDKAYHSHHMLPCAEEYLRALERSGI
                     NPLQGRDDCVWHSSTYENRHVHGARDLAGQYWADNMVRPVLFSHCVDAAAAGSEARFDF
                     AVELGPHPTLKGPALQTIQEAHKVTVPYTGLLQRG"
     CDS_motif       complement(18920..19024)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_pydA_0005"
                     /evalue="4.20E-11"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="pydA"
                     /protein_end="683"
                     /protein_start="648"
                     /score="35.2"
                     /tool="antismash"
                     /translation="GVRFQAVVGHSSGEIAAAYAAGYLTRDDAVKVAYY"
     CDS_motif       complement(19229..19276)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_pydA_0004"
                     /evalue="2.50E-05"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="pydA"
                     /protein_end="580"
                     /protein_start="564"
                     /score="16.7"
                     /tool="antismash"
                     /translation="VFTGQGAQWATMGREL"
     aSDomain        complement(join(19616..19960,20052..21011))
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_pydA_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="1.10E-167"
                     /label="pydA_PKS_KS.1"
                     /locus_tag="pydA"
                     /protein_end="451"
                     /protein_start="16"
                     /score="550.1"
                     /tool="antismash"
                     /translation="IAVVGSGMRFPGSSSSPSKLWKLLLKPRDLLSRIPENRFNADSFY
                     HPNSSHHGTTDVQESYFLEEDHRHFDAAFFNIKPVEAHAIDPQQRVLMEVVYESLEASG
                     MTMESLAGSPTGVYVGLMCADYAELVNSDVNALPTYTPTGNARSIMSNRISYFFDWHGP
                     SMTIDTACSSSLVAVHEAVQLLRSGDSDVAIAAGSNLMLAPLQYIAASKLKMLSADSRS
                     RMWDANASGYARGEGVAAVVLKRLSSAIADGDHIECIIRETAINQDGRTKGITMPSSKA
                     QADLIAKTYAKAGLDPRNPDQRCQYFEAHGTGTAAGDPKEAEAISKAFFHPGEVVSGAS
                     DPLYVGSIKTVIGHTEGTAGLAGLLRASLAVQHGTIPPNMLFDSLHPNVEPFYTNLKIA
                     TEPTAWPKLAEGTSRRCSINSFGFGGTNAHAIVENY"
     CDS_motif       complement(join(19958..19960,20052..20096))
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_pydA_0003"
                     /evalue="3.50E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="pydA"
                     /protein_end="337"
                     /protein_start="321"
                     /score="10.1"
                     /tool="antismash"
                     /translation="YFEAHGTGTAAGDPKE"
     CDS_motif       complement(20301..20339)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_pydA_0002"
                     /evalue="3.80E-03"
                     /label="PKSI-KS_m4"
                     /locus_tag="pydA"
                     /protein_end="253"
                     /protein_start="240"
                     /score="10.6"
                     /tool="antismash"
                     /translation="WDANASGYARGEG"
     CDS_motif       complement(20481..20528)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_pydA_0001"
                     /evalue="5.40E-07"
                     /label="PKSI-KS_m3"
                     /locus_tag="pydA"
                     /protein_end="193"
                     /protein_start="177"
                     /score="21.4"
                     /tool="antismash"
                     /translation="GPSMTIDTACSSSLVA"
     gene            complement(<21955..>23253)
                     /gene="pydB"
     mRNA            complement(<21955..>23253)
                     /gene="pydB"
                     /product="PydB"
     CDS             complement(21955..23253)
                     /codon_start=1
                     /gene="pydB"
                     /note="lipocalin-like Diels-Alderase homolog"
                     /product="PydB"
                     /protein_id="QXF14601.1"
                     /transl_table=11
                     /translation="MMHQSLGLGLVVFVAAPVVAFQTQYPLSPPFPERLHEEWDESCSI
                     SKSTAFETFKGPNNFSTSPSEHIHSVKITPSINATNWEQWEFDGLSHTGLSGLLMAFSR
                     DASYAFFGQGNLRVEFYITLGDGTVIQELDYISESYVADCPGFTAGVWNSSDRSYSFHV
                     TKDHQFARLKFDSWRVRGGFTMSSSTKPHLADGSPWTADGGKADATEISPGLHYGLSMG
                     GADVNVDATLSSGRRIAFKGRGGSTRLWATDGWLKLCEGWKVFRAWAGPYSIVYWDVMG
                     RMGRPGKYVSGHLFYNDELLVGSRVGNVSAEEDYVLFTDNYDGEMSGRYKDKNTGHTFE
                     FASPSKDKKWKFDMQHVVTQYEMGAGAGFGMSGFANRVVGGEVGGVQYEGKGHSEQTYW
                     PEYIEEWKIWLVWGFGFLGKGKTYVMKMVSYVL"
     gene            <23726..>24914
                     /gene="pydC"
     mRNA            join(<23726..24234,24359..>24914)
                     /gene="pydC"
                     /product="PydC"
     CDS             join(23726..24234,24359..24914)
                     /NRPS_PKS="Domain: PKS_ER (29-148). E-value: 8.1e-16.
                     Score: 49.8. Matches aSDomain:
                     nrpspksdomains_pydC_PKS_ER.1"
                     /codon_start=1
                     /gene="pydC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028:crotonyl-CoA reductase / alcohol dehydrogenase
                     (Score: 73.9; E-value: 2.1e-22)"
                     /gene_kind="biosynthetic-additional"
                     /note="enoylreductase"
                     /product="PydC"
                     /protein_id="QXF14602.1"
                     /transl_table=11
                     /translation="MSPPALPSHHRAIVQANTDPVTFEISENRPVPVPLDDEILIKVSA
                     VALNHCDYKMPGRVPCPGAVNGADYSGTVVRMGKKAELESGLRIGDHVAGAQVASSRRA
                     PWAGAFAEYIRHHHSMVWKVPDGWSWEKAAAIGCATTSTVGMALWITLGLTGTPEEPAQ
                     EPEFVLVSGYRVVTTCSPKNFAMVESYGAEKAFDYHSSTCGEDIRAYTENRLQYVLDII
                     TEARTIRQCYAAIGRGGGKYCGFELLPDDLLSTLRKSVKADWTMGLELTGNEVDLPGGY
                     YRAANPEMHKWFVLWKQRYVALYDAGKLKPHPITVREGGLDKVIDGIETMRRREVSGEK
                     IVYPLYNNSSKGVV"
     aSDomain        23813..24169
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_pydC_PKS_ER.1"
                     /evalue="8.10E-16"
                     /label="pydC_PKS_ER.1"
                     /locus_tag="pydC"
                     /protein_end="148"
                     /protein_start="29"
                     /score="49.8"
                     /tool="antismash"
                     /translation="PVPVPLDDEILIKVSAVALNHCDYKMPGRVPCPGAVNGADYSGTV
                     VRMGKKAELESGLRIGDHVAGAQVASSRRAPWAGAFAEYIRHHHSMVWKVPDGWSWEKA
                     AAIGCATTSTVGMAL"
     gene            complement(<25464..>27287)
                     /gene="pydD"
     mRNA            complement(join(<25464..26868,26974..>27287))
                     /gene="pydD"
                     /product="PydD"
     CDS             complement(join(25464..26868,26974..27287))
                     /codon_start=1
                     /gene="pydD"
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 310.7; E-value:
                     2.1e-94)"
                     /gene_kind="transport"
                     /note="transporter"
                     /product="PydD"
                     /protein_id="QXF14603.1"
                     /transl_table=11
                     /translation="MLQEDKSSETMHDPSTRGVETRNVTAVDSPLETATTSESPETERT
                     NVAPAKRDWRFWALLVSISLAGLLTALEGTITSTALPSIVNDLGGGHLYVWVVNGYLFA
                     MTAMQPMYGQLANIFGRRWPMLGATALFVLGSGICGGATNIETLIAGRILQGIGASGTT
                     VLTETIICDVVPLRERSKFLAIVMGMIFLGTALGPFFAGLIVQYSTWRWTFYLALPVGG
                     AALVALFSFLKVKYQKETNLATKISTIDWAGNALFVAAISSVLIGLSWAGSVYAWSSFR
                     VLVPLFVGIAGMGLFMVFEGSRFAPNPTVPLHLFGNRTSVGVMIMTFFHGIITIWQLYF
                     MPVYFQGVLGSSPSRSGVQILATILAILPAAGIGGFLMTKMGRYKPIHYASWAVTLIGL
                     GLFSLLDSGSSTGAWVGFQIVYSMGAGMLVPTLLPALLAPLSESDTALGAATWSFVRSF
                     GMVWGTAIPAAVFNTRSDQLAPELINSPALRADIMGGKAYEHATSAFLGTLSDAASEQM
                     KNVFSRSLRQTWLVSLAFAGMGLLAATLAREVPMRSELDTEYGMEERKPKKASEA"
     gene            <27824..>29034
                     /gene="pydE"
     mRNA            join(<27824..28489,28603..>29034)
                     /gene="pydE"
                     /product="PydE"
     CDS             join(27824..28489,28603..29034)
                     /NRPS_PKS="Domain: PKS_ER (35-362). E-value: 2e-16. Score:
                     51.9. Matches aSDomain: nrpspksdomains_pydE_PKS_ER.1"
                     /codon_start=1
                     /gene="pydE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028:crotonyl-CoA reductase / alcohol dehydrogenase
                     (Score: 124.7; E-value: 7.3e-38)"
                     /gene_kind="biosynthetic-additional"
                     /note="MDR"
                     /product="PydE"
                     /protein_id="QXF14604.1"
                     /sec_met_domain="ADH_zinc_N (E-value: 1e-17, bitscore:
                     53.9, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSTMRGWVRQHRGPYESSLKLIDSLPVPPDPGSDSSDIIVRVSY
                     VALEFSIAHIMGIFPALPFAPPLVPEICVSGTVASAGGKAPEELRQPGTQVLAMTDPMS
                     MMLFGTGALKEYMRLPEQYVVPLLQPSHSVTTDHPHGTAERPQALTLAEGAGLISNGSA
                     AQAVVRAANVLSGQRVLVNGASGSVGHIVSQLCRARGAYVVGVASGVNQDFVRRYGCNE
                     FVDYTKHTDLPEYLASTYGSQPFDSILDCVGSQDLYANSPRYLLPGRPLVNIGAFSMTD
                     SLLSTLYQWSMNSWCPTWLGGVPRPYILFSNTPDMQGVLSLVEMVQQGKLKVHIDSEFE
                     MEDLIKAYERVTSKRARGKVLIRIH"
     aSDomain        join(27929..28489,28603..29022)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_pydE_PKS_ER.1"
                     /evalue="2.00E-16"
                     /label="pydE_PKS_ER.1"
                     /locus_tag="pydE"
                     /protein_end="362"
                     /protein_start="35"
                     /score="51.9"
                     /tool="antismash"
                     /translation="SSDIIVRVSYVALEFSIAHIMGIFPALPFAPPLVPEICVSGTVAS
                     AGGKAPEELRQPGTQVLAMTDPMSMMLFGTGALKEYMRLPEQYVVPLLQPSHSVTTDHP
                     HGTAERPQALTLAEGAGLISNGSAAQAVVRAANVLSGQRVLVNGASGSVGHIVSQLCRA
                     RGAYVVGVASGVNQDFVRRYGCNEFVDYTKHTDLPEYLASTYGSQPFDSILDCVGSQDL
                     YANSPRYLLPGRPLVNIGAFSMTDSLLSTLYQWSMNSWCPTWLGGVPRPYILFSNTPDM
                     QGVLSLVEMVQQGKLKVHIDSEFEMEDLIKAYERVTSKRARGKVLI"
     CDS_motif       28349..28393
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_pydE_0001"
                     /evalue="9.50E-04"
                     /label="PKSI-ER_m5"
                     /locus_tag="pydE"
                     /protein_end="190"
                     /protein_start="175"
                     /score="11.9"
                     /tool="antismash"
                     /translation="GQRVLVNGASGSVGH"
     gap             29306..29405
                     /estimated_length=unknown
     gene            <30413..>31038
                     /gene="pydY"
     mRNA            join(<30413..30466,30535..>31038)
                     /gene="pydY"
                     /product="PydY"
     CDS             join(30413..30466,30535..31038)
                     /codon_start=1
                     /gene="pydY"
                     /note="hypothetical protein"
                     /product="PydY"
                     /protein_id="QXF14605.1"
                     /transl_table=11
                     /translation="MATPGNVTFKNTHDSWGMNWGLCDSSEQMLTMQGMPWIMRKLASW
                     ISVTVVIKTWTDPETGETRFLLQHNPPMGLPGMSEERALDYVPDELTVPNLGKLRVRTR
                     WGTAKELDQLDKYLARGLEKGPHSMIHMMTEHLDIDAVTHQIFGYEEIDGTRYHVRRIV
                     VRKGHEVARLRLVYNYLGPRAG"
ORIGIN
        1 caaaaaacat gatgcatatt cggtgctcgg gctctctcgt aaccacttct agggcacttt
       61 gatttcgctt tcaaatatat ggattgaagt ttatcacact cgactattga aaggtaaaca
      121 cacccctgtc cttgaaggtg aaatttgttg ttgaaatgca ctttcgaaat cagtcgaatg
      181 acgaaggatg gaagcaaatg cgtccaatga aacaggatca aactcagcat ttcaggtagg
      241 aatgtacgaa aatcccatca gtctcacagc cctcggccac gctggcaaat acagagttag
      301 tccagaaccg gccagttcac caaattcggg cgagacggac atgctacagg gtagcgtatc
      361 tcaccaagtc tgaaagtaaa gtcgtgcatc actggattac gtcgcgattg gaggagacca
      421 cttgtggcac tgctagagca gtcagtcatt tgccattgac aatgtacgtg tacggaaaga
      481 gaggtgtagg taggtaagta gtggaatata tcacgaagat cgagagccag ccttcgggcc
      541 atgttagtca gcaccgccgc ccctgctcag gctttgatca ctgatgcttt ggtcatcgta
      601 gccttttcct cttgtcaagg gaccggatac gaatctatca tcgactgccg tcaacgccct
      661 tgtgttcgcg ctgtatttcg tcaacaaaaa gagaaacatt gccttgcctt ggaattcagt
      721 cggttgcgcc cgtggcgagt ggctgagggc aagtcagttg gcgagcccga tttccagcct
      781 cgtccgcccc tgatctcgcc atccttccta ggtatctaag gtagtaaggg acctgtccaa
      841 ctgatctcac tcgactttgt cgctctctat ctttgcgaac ttttgcggcc gggtcgctcg
      901 ctgctacttg atccccaatt ccttcatccg cttcgcagat agccgagcag caatgcccgg
      961 taaggaggac gcgcgagact tctttcgcca agggaagaga tgaaaggctc tagctaatgc
     1021 accgaaggta tagtcgagtg gctgtgaacc aagtaacaaa gaatcgtatt caagggcggt
     1081 gctagtctct atcatatcaa aaactacagc tcaggacgct tgatatcaaa atgcttgtcc
     1141 agaaactcaa acgtcttctg cgccagcaac gcccacgcac caatcttggc cgttagaccc
     1201 ccctcggcca catccgtcgg tacccagacc tccttgttgc tgtcaggtac attgctgagg
     1261 aggcgatgaa tcttaaaggt actctcctcg gccgacgaat acatgtcttg tcctgcacca
     1321 ggccctgtga gaaacacggc gcacctgatc ttgtctaaga tcggaacctc gccagccgct
     1381 ggctccaagg tgaagtcctt gaatcgtctg aacatggccg tgggcttttc agcacccatg
     1441 ctgcttcttc caaggttgat ctcccatcct gactgaaagt ttcccctgcc atgcacgtct
     1501 gtgaacgtgt caaaggtcga gtctggaacc cagccgctgt cccacagctt gaagaaggcc
     1561 ttgggggcgc ggctcaagca cagctcccac aagctgaaga aagggtcgat ggatatgcac
     1621 gctttgaccc ggggattagt cgctgcacga agggcaaagt aaccgccggt ggcggcccct
     1681 gccatggcaa gccttccagt atcgagctcc agtgttggac gagactcgga gaggttgtcg
     1741 agaaattcca caatcttctc tgccacaacc tcaaagtccg gcctcagtgg gaccttggac
     1801 ttcttcagaa gcaggccttg acctgggcct tcgaggcaga ggacggcata gccaagctgg
     1861 ggcccggtgt gcccatacaa gaagtacagc tcctcctttg tcgaatccgc cccggctgca
     1921 tacatgacga tgggtacctt gcccggcagt cgggcatacg aaggaggcag aaacaggtac
     1981 ccgggaagag tgatgccttt ttcgtacggt atctccacac atataacttc cccgtccatc
     2041 agcacagcgg ccttcttgaa actgctgatt gactgctcaa tcaagggcac cacgcgggca
     2101 tcatcgttgc tgaacatgta cggcgttacc cgaaagtagt tggaagctcg aaggtacgca
     2161 ttcctcgcca gaagtctata cccagccttt gcggcttggt ctccaatgcg ctgtgcccgt
     2221 tctgcctgct ctttccatgc aacactccag gattcggggt catccttctt gatcttgcca
     2281 actgcacttt tgaactcgcc gacgtcgcag ccgccgcttg atgcgctgcc gagaagtcgg
     2341 gtgagctcga aatcgaacat gaaggagctg gagaaggtaa acatgatggc cttggtttgg
     2401 tggctcaagc ctgaggaaaa tagtgatgca attgatcaac gggggaaggc cggcatagat
     2461 gttctccaaa cttattcaac gcattcgcca gaaaagggtc cggcaagtac ctacaggcat
     2521 ctgctcgtgt ggaaagtctc acctcacctc ggctctgtca atgtatcggc cgcattagat
     2581 cagttgagat ggtatcagac catttgaggc catttggagc ttcggcacat agccttgcag
     2641 agaagacttt caactttgct cgtgactttg gcaaagcctt tgcctcgtcg ccattcggac
     2701 catcttgatc ggaccgtgtc atttgaattt tcgggacttt tcttttcggc gtgtcgcccg
     2761 ggactttgcg agtcgctgcc tgggagaatc tcctcacctt gcaggcgcat tctcaccgtg
     2821 caggatgcat tatcttgcag cggcccggac aagtatatgt cagacccacg gctgctgtcc
     2881 ctctacatcc cacagttccc ttgcaagaat ggcggccata tacaagcata gcgtaccgcg
     2941 tggcttgcca tgctgtgatg gaattcagcc ccagatgtcg cgatgatgat cccggcggac
     3001 ccacaatcga cattcaagac cggcagcacc aatgtggcca acgtaagccc gtccatggat
     3061 ctatacaaac ctgtcaggga ggtaacagca cgaggtggcc tgcagatcat gaaagtgttg
     3121 gcgcacatct tttcccggcg tacgttggag tttgcatgcg ccccgggtga agaggacggg
     3181 cgaagacaga cagagacttg tagctgttct agtggaacaa gttagtcaag ttgcggggag
     3241 caaaggaaac cacgaaataa tagtactcta ctaccatgga gcatgatgaa cccatatttg
     3301 caacttcaat ttttcagcgc gctccatgct gggcgagaga aaccactttc cctcggtgtg
     3361 tgaaggctgc agataggcat agtcgtccaa ttgattatag agtctaaagg acttggtgta
     3421 ctgcaggcgc caatcctcac gacatgcatt cgctaaagac gggccgttct cgccacggga
     3481 cgactcttct agcttccccg ttccgggctc tactactaat acagtatcat agcccttgca
     3541 ttagcgttca gcatgaggac ggacttagcc cgcggacact gtctcgatgc gcacctggtc
     3601 atcagcctat tcctgctggt ttgccgtacg aacggaggtc agctacattg gtacttcagg
     3661 attcttggta ggctctgata gacctagtat gtgaagaaga agagaaaaca aaagagagag
     3721 aaccgccttc tactcctggg cacctcgggt aagccacagg gcgttgtctg cagtggccac
     3781 aggggacatt cggcctacgc catttagggg ggtatgcacg tgatatgtat gcgcggagtg
     3841 acgcgtgaag gtgatggagg gtggtgcatt ttgcgtcctg aggcactatt gcctggcacc
     3901 tagactacta ggtaccgctt ggtcaatcat agctaggagt cacgggcagc cacaacctaa
     3961 cgcgagacgg cagcaagctt cctggcctgc atgtggcaat gcgagaccgc cgtctcaccg
     4021 agtgctcgac atgccgctcc caggcacgtc gggcgagtca gaactgccat atcccgcctc
     4081 taacgtgtcc tggatgaggc gccggctgac gtggggctac gcgaacacaa ccaaagcgac
     4141 ggccacaccc acaagtccac aactgttgca gatccggttt gcgcggatca agccagtaag
     4201 cacggatctg gatccttgga gggtccgcgc gggcattggg ctgagcaagc cgcgtcctgt
     4261 ggctactcga ggtccccagg gaactgacta atggaataca taactgacaa gtaggtattc
     4321 acctatatgt gaacatgacc cacgagggcg aagctcatca ctcattgaga tcgggatagc
     4381 tcatcaacta gccgagcact acctagagaa gctagcgtgg actgggagaa gggcttgttc
     4441 gaacgctctc ttcatgatca agtcgccaat gcctggagtc aaaacccatc aacggcacca
     4501 acaagttgcc tgtgaccgat gcagaggcca gaagctccgc tgcatacgga actcaacccg
     4561 gtacgactcg tgtgagcgat gtcacaaagc tggtgcgacc tgtgttgtcg atccgtccgt
     4621 tcgcatgggc cgtccgcagc gtgcggacaa gcaacgtcgg gagacagacg gtccccaaaa
     4681 gtcccggccg tcattaacac aggcgcaaaa gaactcgacg actatccgga tccattccga
     4741 tgaccatgat caagggcgtc ctaatacgaa tggttatgct cggcaagaac agcatgcttg
     4801 ggaggatgca agtcttcatt ctcttgattt cagactgtgt cacagcagca acctggaaga
     4861 tgacgagatg catggaacgg cgacagatga catgatacca gtcaactttg actttgtctc
     4921 tccgcaagta ccgcatgcaa tgtcggacct cggcatgtac gacttcggat ctgaagcaac
     4981 ggccagcgac ttgttggatc ctgagccgtg cgcccaattc atttctctgg cgtctcactc
     5041 agccgcggat catgttgaaa aggccacggc agagcgtccg ggcaacgatg ggtcttcctc
     5101 tccgtcttct tctctcctcc gaacttcatc atcgccgtca caacaggcgg tcgagaagct
     5161 ttcggatctg aatgtgcaga tccaccggca gttgaccact gatcatggtt cattggactc
     5221 ggcagggcgg agaactcagc tctcatgtgc cgtggtgtcc atgattgagg gcttgaaaac
     5281 tttccgcgag ctgctcttcg atatcctcag cactacgagt aggagtcctc tacaggcagc
     5341 ctttcgcgat gggcagaaca acggcacctc gcggccgaac actgcggctt cccagaacat
     5401 gcagcagcac cgtcgctcag gaagcatgtt gagcctctcg gattgcgacg cggtatctct
     5461 gtccaattca aacagcgata gccgtccgtt tcaagagggc tcacaccatt tcggctgtct
     5521 agacatgtca acaagtcttc ttctcctgtc atgctacgct aacctcatcc tgctctgtcg
     5581 agaagtcttc gcggcaatcc gacgcgcact gcccatctca ggtcaccagt ccactcttct
     5641 cgaactttca ggctttcgca ttggcagcgt ggcggtacag gaggactccg acttgcaaat
     5701 cacaattctc atccaggtcg tcgtcaggct gatcgacggc atcgggcact gcctcggcta
     5761 cccatacagc tccacgaccg aacgaggcga ggccagcccg tctgacagag gcatctcgct
     5821 cgaactacta gatcttgtct tggggccaaa gggaaggcag ggacaaccgt cgcacatagg
     5881 tcaaatagag gcgttgcggg aagacatacg gaatctaagc aagatcgtct acaagtcaat
     5941 ataggcgaca ctcggccatg ctgcggatga gggaggaatg ggcttcgtgg aatccagagc
     6001 tttatcgcag aggaggcaag ggcctgatac tacaaacata cagcatacat ctccttgcat
     6061 gctgcgaatc aggatctaga aagccatgtg gtgtcaatgt tagagctcga ctacattcgc
     6121 gattcgtgga gatactgaaa gcggccaaag gggggggggg ggagctcaaa cttggtgtta
     6181 tcacgggaga agtatagcca gggtggtaag tttatgaact tgccgcataa ggttccaaca
     6241 cttatcaagg acaggataat gctagctgtg gtgctccacg gagaagcttg tcatgctatg
     6301 cattacacag taacgtcata cccaattgca gcattcacag tacaaaagaa cacagacctt
     6361 tctgcgctgg ctctgtcact ataagcaaca agtcccccat ttcatgacaa cccactgtcg
     6421 tgcctttgcc tcacctcacc tcacctcacc tcaccagtat cgcggcgccc acaacgctgc
     6481 acagaatcat gtgcggaacc gggctctctc ccagcttcat gtccgaatag aagcccacac
     6541 ccaacaagac cagggagaac ttgagaccga agctgcgcag ctcctccgag aggagcagag
     6601 ccgtgatggt gatgttgatc accacgaaga cgtatctcag agcgcgggtg gacatgccgg
     6661 cccaccagaa gacggccctg ttgtgctcag gaagcttctc gctgaggttc ctggagaaag
     6721 caggcgtgaa cctggaggtc aggtgggctt ggacgcagag ggcgctgaag ccggcgatgc
     6781 tgtatgacag ccaatcgctc aggacgtggg cggaactcat ggcgagtgcg tgtgttgttg
     6841 ttgttgttgt tgttgatgat ctgattctcc gtgtgactgg attgcaagta gaccagacta
     6901 tagagagatt gacagaaagg cgcaactggc ccttcttctc cagctcgaga acctcttttt
     6961 gtaacgctta caggtacgat tcttgggcat gtccgctgga tatcggaggg aggagcgcca
     7021 accccccctt ttttgctctt ggacagcaac acggagagtt gtcgtccagt gcggtgaagt
     7081 aacacgacga gacatgagat gcagaggaga gccgtgggca gaaaatctcc gattgtccga
     7141 accctgcctg gaggcccccc cccccccccc cccccccccc cccccttctt caccttgtca
     7201 aaaaatgtgc cgaacgcgaa ggactcactc gggggatttc tctctctctc tcgtcgcgtt
     7261 tgggactcct gctttggtca gtcgggactt gtgtgtgtct gggcaacgga ggtccgagtc
     7321 ctcgccttca gctgctgcag aacgctgcat tgccttgcag acggtatgca ggccgaacat
     7381 gcgacactgg catcgactga tgcgcccaca aggttgttgt gtttttgttc gacgatgagg
     7441 ccgcactggg tgaaatgtcc accttgccct gatgcatccg cgtttgggac agtggtgtgt
     7501 gtgtctcccc ccctcccccc ccgggccatg ttgatattca gtggcgatgc aaagctggag
     7561 tcaatatacg caagtttgta tctcagtcat ctggttctcc atcaccatgt ccctcatcgc
     7621 attgccactc cgcctcctcc gcctcctccc ggccatcact tccacatggg tactcgcctt
     7681 tgctcttgac gagcacctca tcttcggaac ctgggtgcag ccttccctcc gcgagagcgc
     7741 aaacgccaac ctcccagctt ggtggacaac gggaggcttg cggtggcgct ggatcctcat
     7801 cgtggtctac cccatcaact acgctctcgg cgtcgtcaat ctgttcgtcg gtcgagatga
     7861 gcttcgagcc acgggcgcca tgtcgtggta caccatcggt ctgctgttca gtctcgcgca
     7921 catggggtac atgagaacgg ccttggatcg gatcgggatg atcgagcgcg gggtgccgag
     7981 gggaaacgtc acgtcctcga tggaaagctg gttgaggatg aaccgaactc gggccttggt
     8041 cacagacctg ccggcctgga tttgttttgt cacggcggca ctgaaggcgc tctgaagtgc
     8101 tgaagttcct gaagttagta gagaagcata cctgcagcaa agcggtcaag agatttcggt
     8161 gcggaggaga ggcagaacct tgatattgga tcctgagcgt agatctaagc tctcatagat
     8221 tccagttttc ttcttgatgg aaacacaacc gggattattc taacttttga cgactgtgac
     8281 tgaaggattg gtgacgcccc agccttctca ttcggagcac ataaaggcac aatagagagc
     8341 catctcataa ggacagagtc aagttactcc ataacgccgt tgacgaagat gaagcctcag
     8401 gcacggctca ttgtttctct ctctaccaga ctatagagtt ccagacgagg atcaaacaag
     8461 aaatacaaag gataaaaatc aagacaccgc tggaacgcct cacatgcctt tttttgcctg
     8521 gtccgtcttc agcaatagct tctgaccaac tgaaaggccc tggcctcggt ccaccgagag
     8581 gaggaactcg ccgatcagag gattcatgcc cttctggacg gccctgctca cccactcagc
     8641 catcgcgagt gaatcccact ccggttcgtc cttgggactg agcacggcct tgatggactg
     8701 tgcagggatc accttctccc cagtttgatg aaggaactgc gtctcgggcg ccgtcgtgcc
     8761 caggtctggt ctgtcctgca acacagagcc gatgatgcca gcggcagctc tctcgacact
     8821 gatcagatcg acatagccgc tccacttggc agtgtcaggg agggctttga tgagtgatga
     8881 gtacttgagc aggttgggca cgatatcatt ctcggccgcc tgatcgcccg tgatggagga
     8941 cgggcggtgg atgaaggtag gcagaccgag cttcttggtc gcgttctcca gaaagacctc
     9001 gctcgcccac ttggatgccg cgtagccgtc ggagaatgtt gcgccggggg ggaaccgggc
     9061 gagcgactcg ggagccagag tgtctgacct gttgagcttg cccaccgtag cagtggagac
     9121 gtagtgcaga ggaatcagcc gaggaagcga gagcttgaca agctccttcg tcgagaggac
     9181 gttgggcgct ctaagagagc tgtaggactt gaggaacgaa acgtcagccc cgttgtggat
     9241 gatggcgtcc gtcgaccgga agatggagac ggcgtctgcc tcagacagtc cacatcgcgg
     9301 ctgtgcgaga tctcctgggt gaatggagac cttgtctgaa cctgcgaact cggcaagctt
     9361 ctcaacgttg cggacggcaa tgcagtgcac tctgtgtatg tttgcattcg cgaccaaaag
     9421 gcgcaccaac tgcttgccga ggaatcccgt ggcgccagtg atgacgacgg tcctgggtga
     9481 gctgtggctc tgcaagtgtg ccggctgcac atcaccctgt gcccagcttg acgggacctg
     9541 agtttcggct tcccatccaa cctcagggac ctgagctaca gtggagagat cctgtattac
     9601 tgctgccatg gccccgagcg tgctgctctc aaagaggcgc agcagtggaa tgtccacctg
     9661 cagtctactc gccacaagcc gtcgaagctc gataaggagc atggagttgc ctccgacctg
     9721 gaagaagtcg gaggctccat caatgaggtg tacttcttgt agctgctgcg gtaagacgtc
     9781 cttccagatc tgcgccagct cggattccgc ctctgtgagc tgtgttgccg ccccctggtc
     9841 ctggatgtga ctctggcccc gagtgcttga aagctctaac ccctgcagag cacgccggtc
     9901 aaccttccca gatgcagtca gaggcatgca atcaatggga atgatggctg ctgggcgcat
     9961 gtactgcggg agtggaagcg aggcagacaa gtcgcggagg tactgctgct tgttgctgaa
    10021 cgaggcattg cgagatagaa ccacatgggc gacaaggatg gttggatcac cccgaggagt
    10081 aaccccgacc tcactgatct gcccttcaga agcgtctaag atggacttct cgacgtcttg
    10141 catctcaatg cggaggcctc tcagcttgat ctgggtgtcc ccttcgatgc gaccgaggat
    10201 ctgcagagta ccgtccggtc tcagcacacc cttgtcccca gttcgataca tccggcccca
    10261 gccttgtccc atagcagagg aggatgcctt cgggtctacc aggaacttcc tcgcagtctc
    10321 ggcgggattg ttcaggtacc cgagggcgac acctgctccg ccgatgagga tctctccggg
    10381 ccatccaacc ggcaggggat ccaaactgtc gtcgactaca tagaacgagc agttcggcag
    10441 agccttgcca gcagtgatct gcctggccga agaggaggct tccaggctta ccttcatctc
    10501 gtttgaggac agggtgcact ctgtcggccc ataggcattg aatgcgtgga agggatgctc
    10561 gaactgggtt ccaagtgttt ggaacgcctc caaaagctga ggggtgaact gctcgcctcc
    10621 agccgtggca aacctccatg atgtactctg gaagaggctg ttagagccat gtcgaagcca
    10681 agcaagatac tctgatggag ttgcgctggt gtatgtgatg ttctgctcca gaatcatctt
    10741 tgccacggca gccgagtcct tgcgaaacgg ctctgggaca aggacgagcg tcccaccgtt
    10801 ggccagggac atgaagatct ggtttaggga catgtcgaag cccacggagc tttgctgcaa
    10861 gaccgtctcc cggccgaacc catgtgtgtg tacgagggcc tcgacgtggt tgcgcaagcc
    10921 tccgtgggaa agaatgacgc ccttgggcac tccagtgctg ccgctggtaa agaggatagc
    10981 ggcaggatcc gtggcacggc gggcagtggt cggacagatg gcgtccttca cgcgaggagg
    11041 cagggaagag acgtccaaga cagtgaccga tggcgggagt gctagatcac cggctcgtgc
    11101 caatgtcgtt tggtcgagga gaagaacaga aggatcgcac tcggtgatga tgctgcggag
    11161 ccttgcttct ggtagattgc tgtccagggg cacatatata ccgccgaccc ggaggatggc
    11221 gagaagggag aagacgaggt cgggggaagc ctcttgatga actgcaatca ctgatcctgc
    11281 tgtgacgttc acttgaagca aggtagatgc cattctgttg acttgttgcc cgagctgctc
    11341 ccaagtccag gatcggccag tatgatctct tagagcaatc tcctgagggg ggttcgcaat
    11401 catagcgtcg atacgatgca ccagggtctc tgagccctga gatggcaaag cggctcctgg
    11461 acaaaattag ttatgatggc ttcgcaaagc ttggagtgat ctgcgccttg caatggtggg
    11521 atcggagata tctcacctcg gccaagctgg acggctttgt cgacgtccga tcttgtgaac
    11581 aacgagacat ctttcaggat ctggccagga gagcctgaaa gttcgctcag gagattgcag
    11641 tacagctcaa gcacttgtgc tgtctcctct tcggagtaca gggcatcctg aagcatgaag
    11701 gcgagacgcg tgtcgccacc agggttttcg atgatgtcga gagacatatc ataaccggcc
    11761 ctgggaagcg agatcttctt tgtcacgcct ctcgcgctgc ccaacgtccg gttctccctg
    11821 acgccttggc gatagttaat gaaggcctgg aaaagaggac tgaacgctgt cgagcggtcg
    11881 cagttgaggt tgtcgagaag agcatcgaac ggcaacctcg agttggacat ggcgttgtac
    11941 gcttttctgc gcgtgtcctt gagcacagtc tcaaaggact gctgcttgtc aagtcggaat
    12001 cgcagcggaa ggagattgag atacattccg atgctttgag caacctgatc atcccaacga
    12061 tttgcgtctg ccatgccgat gcagacgtca ttcttgccga acagcttgaa gagcagcacc
    12121 tcgaacacgc ccaggtagaa gtggaagacg ttggccttca acttgcgaca agtgtccgag
    12181 atctgcctcg ctaccttggc gtcgacggtg cggctcacgg aggtgtgtct ataagctgtg
    12241 agggccttgc gctgcttgac agcggcaaaa gggagcaggg gcaagggcgt cggcgcttct
    12301 gcaaactctg acctccagta ctcaatctcc ttctgcatgg caccatttcc cagctcctgg
    12361 cgcagctttt ccgagtagtc ggagtactgg taaacttggc ttgaaaggct ctggccgttg
    12421 taggctttct gaacgtcgtt caagaaaacc tccaggctga tcccgtccat gacgatgtgg
    12481 tgggagccga tgagaaggta gctctctgta gcattcatgc cgaggtggat gagctgcatg
    12541 cattcgccgt tgatgaggtc gtatgcgtgg ttcttgaggg cttcgaactc ggcctcgacc
    12601 tgggcctcgg agtggatttc cttcgtctgc aagtacaggc gagaggagtc cgatatagcc
    12661 tggacagcct tctggttctt gtcgacgaag aaagaggtcc gcagcgactc gtggcgagcg
    12721 ccaactctgc gaaccgccgc gtcgaggctg tcaagccgga cctggccctg aacagagacc
    12781 agtatagtgt tgtttgccgt tgtctggtcc tccatcaagt gcttcaggaa ccagaatctc
    12841 gcttggcccg gggacacggg aagaaccttc tcgtaagcgg tctccagagg ttcttccagc
    12901 gaggcagtgg acgaatctct ttcctcactt tgcttctcgt cgggctggct ggtcttggaa
    12961 ctgctctcac ttaaatgctg actggtctcg gcagttgtct tggggggatc gctgctcggt
    13021 gctgaagaca cagagcctga cggcggtgat gctggtatga ccggtgccgt gggcgtctcg
    13081 ggaacagcgt tgagggagtc gctcatattg ggcgtcaatt ctccaggcat attctcgacc
    13141 gcgaactcca caagctctgc gatggagatc cctgacaaga ccttgaagac agcaatctcc
    13201 gtatcgatct ccttgatgaa ccacgagcgg atctcgaccg ccaccagaga gtcgatgcca
    13261 agatcatctg tcccggaagc cagcacttga gacttttcag tgtccggcga aatctggaga
    13321 acaacctgca gcttctggta gaatgagtct tgtatcatgt tagttcatcg gaaattcccc
    13381 ccgtcaaagg agtgctggtc cgcgctatca agactcacct tggacaatct cgagcgcttc
    13441 ttctgctgta gttgcctcgg ccagccggag cttggtggac acggcagcat tgtgcttctt
    13501 ctgggcctgt ttgagcgatc cgctgtctgc tgctgcaagg cagtactgga accgggggaa
    13561 cttggcccac agagggagtg tgtcgccgaa cttggacgtc tccagtgccg tgacaacgtc
    13621 gggattgcga cctgacttcg ggtgcgaggc gaggactgcc tcgccgaagc acaagtggaa
    13681 ttcccgctcc gtgaccatca tgtagccagc ccggctgagt gcagtgaaga tgtagtcttt
    13741 gaaccctcgg ttgatgtagc caacccccat gactgctcca atgtggagaa tcgaaccggc
    13801 caagcccttc tcgcgccttt gacttgccag tgaagacatg aacatgttgg cagctgtgta
    13861 agcagattgt ccgcggttgc ccgcaatggc cgtgcaggag gagaagaaga tgcagaagtc
    13921 cagagtgggc tcctggaaaa gttcatccag atagatggcg ccttgcactt taggcctgat
    13981 gacttggatc atcttctcaa aggtcatttc aaagaaggag acatcgttga ggaccatggc
    14041 gccgtgggcg atgccggcga taggaggcaa gttctgacgt atatggtcga caagggaaac
    14101 cagggccgct ttatctgtga tatcgctgtg attcatgctg ttagcctttc ctttttgttt
    14161 tcctggcttc gtgaacgtcc agcattctta ctttgagaaa acttcaactc taactccagc
    14221 ttccttcaga gtgcgcttcc accttgcatc gatattcgga tggcgacttg tcaacacgat
    14281 attccgggcg ccatgcgtca ccatccagtc acagatagac tgtgccaagt cactcgtaag
    14341 accaaagaag acataagtcc tgtcgctcct gaaggtggtg tggctgtcga ccgtggaaac
    14401 ctgaacagga accttcccag tggtgttcca agcgacaatg gctggtgtga atagatcggc
    14461 gtcagaacta ccagggccta gttgatcggc tcgaatcaga ggcaatgtgt ttgttgaact
    14521 ttcaggtgcg gccagcttct ctaatgccct tggcagagcg cccttgaggt tgtcgatcat
    14581 gtcagcaaca gagaagccac gaatgcgtct cagtgacgga aggctagcag atgtcgtctt
    14641 gaggcatgtc tccggcagac aggaggcgat caaggatccg gctcgctggc ttaagcttcg
    14701 tgtcgagcag tcaataaaca cggatatgtc gggagggagc agagacttga cgacagtcct
    14761 aggagaatac gaatgaacct gagtccatga cctgtccgag ggagacgctg ccgttgtgat
    14821 gtacacgtgg atgcctaaag aggcaccacg ctcgacaatg gctgacgcga gatccacggg
    14881 aggctcatgg atggcgagaa cagagccgtc ctcgcagatc gacaacatgc cgtcgacctg
    14941 cagttgagtg tgtagacgtg acagaaggag tggttcttcg ccttgaagag gagcaacatc
    15001 cagcaccctt cctgggggca ctgaagcata ggagccgttc gtttccgaga tggccaagac
    15061 gatcctccca ttctgcccag tgttcgtacc aagaacgagg tacgatggcg gtattgtggc
    15121 aagatcgggc atcaaaagcg aatggctgac tctgatcact gtctcggact cgctctccac
    15181 tgcgtctggg gagccgagca ttttcgatgc gagatgatcg ttcagaacaa gaccaggggc
    15241 tatcgtttgt cccagagaga ggttcatagg gaccgactgc gggttcatcg cctcaagaac
    15301 tgtacgcttg gacgcgttga acctgtcgtt gagaggcgcg gcaagatgga ctcgggagag
    15361 acagagttct ccgttgatgt aggccagttc gtgttcgttt gtccatagca catcttcaaa
    15421 ggtgcccccc tccttggccc atctatcgct ctgccgcagc cgcagcagtg cttcgaggat
    15481 tgtacgggcc tctggctcga taccgggctc cagatcaagg aattgcagaa ccaggtcggg
    15541 attctccagg atcaaagtcc gtccaagacc gactgacatg cccatgtacg gatctgccga
    15601 tctagagcct tgcgtcaccc agagcactgt tcgttgtgtt tcgaaaagcc tcttgaggcc
    15661 ctccagcgtc ctttcagtta ttcccttgaa gactggcttg tccaactcct caaggaacag
    15721 aatggcagtc gtctcagaaa tcgtgctgct gtcaatgtcg tcgacggtct tgacaatcgt
    15781 gtgcgaaaca ttgggagact gaagcatacc aacaatctcc tcaattagat ggcttgactt
    15841 gggactttgg cctccgacaa gcacaagatc ccagtgttcg gcaactggtg aatcagtgcc
    15901 gacgagagca aggggttcgc ggagcagaga gacgcgctcg tcaacggcct gggacacaat
    15961 gacagccagc tggaagggca cagagtcgag ctcgtgcgta gtcgaatcaa cgccggagaa
    16021 gcccgtctga aggagaaggt cattccactc aggcgttgag acacacggcg acagtttcct
    16081 tccgtcgtcc tggcccaacc accagcctgg taaagcgcac atcatgaatc cggttctgga
    16141 gggctcattg ttgcacacct cttggatgac gaggtaacca ccaggcctga gcagtcgccg
    16201 agtgttggcc agcgtttgct tgagattctt ggttgcatga agaaccagag acgcgaccac
    16261 gagatcgtag gaatgctctt catagccctg ctggacaata tccttctcga cgtccagagt
    16321 cttgaagatc atcttgtcgg caacggacga gaaaacctcg gaagcagtct caaagaaatt
    16381 gggcgatatg tctgtataag tgtacgagga aaatgcacga ccgatgcctc ccatgatgac
    16441 cttggtggcg ccaccggtcc cggctcctga tgtcaaggtc agtcggagtt ctaccagata
    16501 ctcatcttct caagttccat ggttttgtgt gtgtgtgtgt gtgtgcttct cgggtttctt
    16561 cttacctatc tcaagcatct tcatatgagg atgacgatga accacctgct ccacggtctt
    16621 gcctacgtaa ccggagaact ccttcaagcc gagcccaact tcgtagaaac ggtctaggag
    16681 attgtctttg gtgatgtgct ccagcatggt tgtctcgccg cgaatgacag caggtaagtt
    16741 gtcacccaca gcccgagcga gcctcatgtc cacagtatct gcgtacctaa tgtaggatca
    16801 gcatctcgtt caagcaacct ttctcactcc tttctctctc tgctttcttt ataactcctt
    16861 cacgccagaa tgctcacctt tccttgattc tctcaatgtc agctgcgcta tcttgcagcc
    16921 actccttctt ggccgttttc cgttgaccag ccccagttgt cgaaagcaca tgtgtgatga
    16981 agttgaagag acagacaaag tgccactcca aattcagaga actgcgagtc tcctcaggaa
    17041 acaggctggc cagctgcctc atgtaataca ctgatactct ctcgatagcg aaagccagtt
    17101 cgtagtcctc tgcagtggcc ctcttcccct gcatggcacg ctcggcgtcg ggagccaaca
    17161 catcccaaac atactcggtg aacaccgcac gatctgcttc cgccgtgggc tcagagaagg
    17221 atacaacctt gagcccctcc atctggacca ggcaagaccc atcctcggtt gagatctcga
    17281 cgtttccatt gagattcttc gtaaccagag gatttcccgt caactgggaa gacgatgtca
    17341 cctctgtcgc agactcaagc tgctgccggc aaaggcctgc attgacgcga cagctctgga
    17401 taccagtcgg tacgtggagc tgatcaaggc taccatctcc cggccagcaa tatgccaaga
    17461 aaatgccctg caaggcagta tccaacattg ctgggtgcag catcagcttg acacgatcgt
    17521 cttcctgcag aggcacccga accctggagg aagagaagtt gagcttcctt tggatggatg
    17581 acattgctct gaaatctcca ctgtagccat aacccacagt ttccaaggac ttgtaaaagc
    17641 gatcctctgg gatgtcgacc aggttgggga ggtccttgct ctgtgagggc aacaagccag
    17701 cggatgcttc accagttatg acgatgactc tgccggtggc gtgagtcgag agctgctcag
    17761 catctgcgtt gctacaggca tgatatgtga aggaagcgga ataagtcttg tcttctccct
    17821 tggtgatgtc gctcagggtg aagacagtct cgattccaga cccatcttct ccaaagatga
    17881 gaggcttccc aagattgaag tctcgaacct ccactaactg ggcgctcgct ccctcaggca
    17941 cgaggaacat ggcggcctcg atggcagtgg acaggtaggc agtggccggg tagatgacct
    18001 gtccctggag ctgatgaccc cgaatccaag gaagctcatt cagcaaaaga tgattcctcc
    18061 acctaatctg ctcatccatg acatccgttg tcctggtgcc tagcagagga tgggggatac
    18121 tcttctgcgt gagaaaggcc tttgtcggac gggacttgtg ccagaagata ttgtcgtgat
    18181 cccagtggta ggcgggtagg tcctgcagca tctttctgct cttgatcccc gagaccaatg
    18241 tatcaaaagc ccccaagtcc actatcgagg gagagaactg agaccagagg tagcccagtg
    18301 catcggagaa ggcctggaca tcatccttgc cccgttgcag gagtccggtg taggggactg
    18361 tcaccttgtg agcctcttgg atcgtctgga gtgcaggtcc cttgagcgtg ggatgaggcc
    18421 caagctcgac cgcaaagtca aagcgtgcct ctgatccagc tgcagcagcg tccacacaat
    18481 gtgagaaaag aacaggtcgg accatgttat ccgcccagta ttggcctgca agatcccggg
    18541 ccccatgtac gtgtctgttc tcgtaggtgc tggaatgcca aacgcagtca tctcttcctt
    18601 gcagggggtt gatgccggat ctctcgagtg cccggaggta ctcctctgca caaggcagca
    18661 tgtggtgaga gtggtaggcc ttgtcgactt tgagtatccg tgcaaacttc ttctcatcct
    18721 caaggacttc tttggcctgc tccacggcat cacggtctcc agagattgtc acgctggagg
    18781 aggagttgat ggccgcgaca gccagacgac ccttgaacat ggacaagttg cacagctcgt
    18841 tggcatcttc tgccgaggta ccgacggcca tcattgctcc tggtcggtca gatggtgtca
    18901 ggctggtgaa gtagcctctg tagtaggcga ccttgactgc atcatctcgc gtcaggtagc
    18961 cagccgcata ggctgcggca atctctccag acgagtgacc aacgactgcc tgaaacctga
    19021 ctcccgcgct cgtcaggagg tcgaaaagca tgatctgcac aacggtgcac agcggctgcg
    19081 agatgacggc agagtcgatc ctggaaaggg gagcatcaca cgtgacttgg tccatgacgg
    19141 accaatctgg tcgctccgcc tcgggaagca actgaagcat gcggtccacg tcacggacaa
    19201 ggtccctgca gtactgtgag tgaagaacga gttctctgcc catcgtcgcc cactgtgctc
    19261 cttggccggt gaagacgccg agtgcccgga gcggcgatga ccatggtctg gatcgcaacc
    19321 caaggttccg gctgcccccg tcgctggacg ttggtgctcg caagaggccg tcaatcttcg
    19381 tgtgcagatc agcaacagaa tctgccgaga cgtgtgtccg gactgcgtgc ccacttctcc
    19441 gagcatgcag tgtgtaggcc agatcgtgaa gagagatgtc ggggtgaagt ctcagatgct
    19501 ccgcgtagtc ggccagaacg cctcgtagag acctttccga ggcagcagag aaggtaaagg
    19561 gggtgaattg gcgacccgga gaagcttggc taacctgcac aggcgctggt ggaacgtagt
    19621 tctctacgat ggcgtgcgcg ttggtgcctc caaagccgaa gctattgatg ctacaccgcc
    19681 tggaagtacc ctctgcaagc ttcggccagg ccgtgggctc tgttgcgatc ttcaggttgg
    19741 tgtagaaagg ttcgacgttt ggatgcagcg aatcgaagag catgttgggg gggatggtgc
    19801 cgtgctggac tgcgagcgaa gccctgagaa gaccagccaa acctgctgtg ccctccgtgt
    19861 ggccgatgac agtcttgata gagccgacat agagagggtc gctggctcca gagaccactt
    19921 cgcccgggtg gaagaaggcc ttgctgatag cttcagcttc ctaagcaacg agaagatagt
    19981 atcagtaagt ctgtctcatc tgatggtcct gaacagcact cccacaagca gcagcagggt
    20041 tccaacatta ccttgggatc tcctgcggct gttcccgttc cgtgagcctc gaaatactgg
    20101 cagcgttggt ccgggtttct aggatcgagg ccggctttgg catatgtctt tgcgatcagg
    20161 tctgcctgtg ctttggaact aggcatggtg attcctttgg tgcggccgtc ctgattgatg
    20221 gcagtctctc gaatgatgca ctcgatgtga tcgccgtctg caatagcact gcttagacgc
    20281 ttcaggacca cagcggcgac tccttcgcca cgagcatacc cagaagcatt agcgtcccac
    20341 atacgtgacc ggctgtcggc tgatagcatc tttagcttgc tcgctgcaat gtactggagc
    20401 ggtgcgagca tgaggtttga tccagcagcg atggccacgt ccgagtcacc actgcgcagt
    20461 agctgaaccg cttcgtgaac ggcaaccaaa ctggatgagc aagctgtgtc gatggtcatg
    20521 ctcggaccat gccagtcgaa gaagtaggag atcctgttcg acatgatact tcgagcgttc
    20581 ccagtcggcg tgtaagtcgg cagggcattt acatcgctgt tgacaagctc ggcgtagtcg
    20641 gcacacatca gaccgacgta gacgccagtc ggagatccag ccaacgactc cattgtcatc
    20701 ccggacgctt cgagcgactc gtataccacc tccatcaaca cgcgctgctg cgggtcgatg
    20761 gcgtgcgcct caacaggctt gatgttgaag aacgccgcat cgaagtggcg atgatcttct
    20821 tcgaggaagt aggattcctg cacatccgtt gtgccatgat gagacgagtt tggatgatag
    20881 aaagagtctg cattgaatcg attctcaggg atcctcgaca gtaggtcacg aggcttgagt
    20941 aacagcttcc agagcttgga cgggctgctg gaagaacctg ggaaccgcat gccgcttcct
    21001 acgacagcga ttggttccct cccgccggca atgctttcgg tgtctctctc ggccttcatg
    21061 attttgtctt gtgaaatctt tctgatatgg ggtgttgaaa cctgaccaag ctggtggact
    21121 tgagagctgt caaaccacag tagatggatg ataggtggag ggctgggagg tatggcacta
    21181 tcactaccaa ggccaagaca gtcacaccga tcctattatc aaagacctcg atatattcga
    21241 gatatagacg caaaccgcct tctggcgtgt tcaagaaaag cgcaggaatt tcccccgagt
    21301 cggggtttcg accaccttca accgagccgc aacccgagga gtcaaaggta agctcgggat
    21361 ttcgatctcc tatgtccgag tcagctgcat tcggaggttt tagataagat ccgagccctt
    21421 tgagagcgca tgacctgata cgtacagcgc cgtaggccag ccgccgtact cagcaacagt
    21481 cacccgccat tcgacggtct cgcagccagg actacgtgag tactatcgtg gttgtgcgag
    21541 ttgacgcaga agtagcactg ccggtgagtg gttcgatcat catgtgattt gcgttgaacg
    21601 tacttgtgtc agcctggttt aggaatacac atgacagaag agttggtgaa tactttcggt
    21661 aacatgcatg gttgctggcg ctaccttgat cttatgcgtg tgtagggcat ccctcgagga
    21721 aatagtgaga atcaatggga aggtatatga agtagaatag agatgctgca aggactttgg
    21781 ttgcgtaatt ggctgtgcaa taaaaccaaa tcttggctag ccagcccaag atccatccat
    21841 ccatccatga gctcctcaga gctggaacct atgttccgtt tctcgaaagc atgctagacg
    21901 acagtctgct caaagcgaat gcctatgaaa gacgagatcg cccgagcaca ctcgctacag
    21961 gacgtagctg accatcttca tcacatatgt ctttcccttc cccaggaacc caaagcccca
    22021 gacaagccag atcttccact cctcgatgta ctcgggccag tacgtctgct ccgagtgacc
    22081 tttaccttcg tactgcactc cgccaacctc accgccaacc actcggttag caaacccgct
    22141 cataccgaag ccagcaccgg cgcccatctc gtattgagtc acaacatgct gcatgtcgaa
    22201 cttccacttc ttatccttgg aaggcgacgc gaactcaaac gtgtggcccg tgttcttgtc
    22261 cttgtatctt cccgacattt ccccgtcata gttgtcagtg aacaggacgt aatcctcctc
    22321 ggcagagacg ttcccgaccc tggaaccgac gagcagctcg tcattataga ataggtgacc
    22381 tgagacgtat ttgccaggcc tgcccatgcg ccccatcaca tcccagtaca cgatggagta
    22441 tggtcctgcc catgcccgga acaccttcca tccctcgcaa agcttgagcc agccgtcggt
    22501 agcccacaga cgggtggaac cacctctccc tttgaaggcg atgcgtctcc cggaagaaag
    22561 ggtggcgtct acgttgacat cggcccctcc catggacagg ccgtaatgta gcccgggaga
    22621 gatctcggtc gcgtctgcct taccgccgtc tgcagtccaa ggtgatccat cagccaggtg
    22681 aggcttcgtg ctggaggaca tggtgaatcc acctcgcacg cgccacgagt caaacttgag
    22741 cctcgcgaat tgatggtcct tggtaacatg gaaagagtac gacctgtccg agctgttcca
    22801 taccccagct gtgaagcctg ggcagtcggc aacataggac tcgctgatgt agtcaagttc
    22861 ttgaatgaca gtgccatcac caagcgtgat gtagaactca acgcgcaggt ttccctgtcc
    22921 gaaaaaggcg taggaagcgt ctctggagaa tgccatgagg aggccggaga ggccagtgtg
    22981 cgacaggcca tcgaactccc actgctccca gtttgttgca ttgatcgacg gcgttatctt
    23041 gaccgagtgt atatgctctg aaggcgatgt agagaagttg ttgggcccct tgaaggtttc
    23101 gaaggcagtg cttttgctaa tggagcaaga ttcgtcccat tcctcgtgca gccgctcagg
    23161 aaacggaggg ctcaaggggt actgcgtctg gaaggcaacg acgggcgcag cgacgaacac
    23221 cacgaggcct agaccgagac tctgatgcat cattgctagg acgttggctt agaaacgttt
    23281 gtcaaaacaa tagctgaagt cgcgaggtag gtagcagttg agcgaccagg ggctcgaaac
    23341 agttgatcaa taagggtaga aatggcagag tatcggatgg tctgtcagag caacagagag
    23401 aaccagcctg cttcaatgat tgtgtaggag gaaaagaacc taagcggcga actggttcaa
    23461 gactcgtcaa gactgatcaa ggggaaaagg ggggaggggg atggaaagtc ccgaacagtg
    23521 aagctgaatt cccgaatcat ggcggccgcc accctttcgt ttgtcagcac cgatggcaga
    23581 tcatcgtgtg acatggtcac atcaaggtag acatttgtag tgctctttgc aagacgcagg
    23641 ttcaaaagag gctttggatt ggaaaacccc tgttcgtcca agaagccaaa gcgacgcgct
    23701 tgaagaagaa gctctgcaca caaccatgag tcccccagca ctgccctccc accacagggc
    23761 cattgtgcag gccaacacag accctgtcac gtttgagata tccgagaaca gaccggtccc
    23821 ggtgcccttg gacgatgaga tcctcatcaa ggtgtcggcc gtggcgctga accactgcga
    23881 ctacaagatg cccggacggg tcccctgccc cggggcagtc aacggagccg actactcagg
    23941 gaccgtggtg cgcatgggca aaaaggcaga gctggagtca gggctgcgta tcggggacca
    24001 tgtagcaggc gcgcaggtgg cctcaagccg tcgggcgccg tgggccgggg cctttgcaga
    24061 gtacatcagg caccatcaca gcatggtctg gaaggttccc gacggctggt cttgggaaaa
    24121 ggccgcggcg atcggatgcg ccacaacgag cactgtaggc atggccctct ggatcacact
    24181 gggcttgacc gggacgccag aggagccggc tcaggagccc gagtttgtcc ttgtgtacgg
    24241 aggcgccacg gccagtggga cgtttgccat ccagttgctg aagctgcaag tttatctcct
    24301 tcctcccgct tgtgattcaa aaaagaaaaa gctgacatga agtgttgtgc gccattagat
    24361 ctggctaccg agttgtgacg acctgctctc ccaagaactt cgccatggtg gaaagttacg
    24421 gcgctgagaa ggcctttgac taccactcgt cgacgtgcgg agaagacatt cgcgcataca
    24481 ctgagaacag gctacagtac gtcctggaca tcatcaccga ggcccggacc atccgacagt
    24541 gctatgctgc cattggacga ggaggcggca agtattgcgg cttcgagctc ctacctgacg
    24601 acctgctctc cacgctgaga aagtccgtca aggcggactg gacaatgggc ctggagctga
    24661 cggggaatga agtcgacctc ccgggaggct actaccgagc ggccaacccg gagatgcaca
    24721 agtggttcgt cctctggaag caaagatacg tggcgctgta cgatgcaggg aagctgaagc
    24781 cgcatcccat caccgtgaga gaaggtgggc tggacaaggt cattgatggc atcgagacta
    24841 tgcgccgaag agaggtttcg ggcgagaaga ttgtatatcc cctttacaac aactccagca
    24901 agggagtagt ctgaatccat gggctcgtgt agatccatcc atacttatct gcccatgcga
    24961 tcctgcacac tggaaatcca tctctccagg ctcttcgtat cgcggattcg cggtcgtaga
    25021 gagcagcagt cacaaagcaa agagtagtaa ttgaggcgat tctaccaaag gtaggaggca
    25081 cagccaaggt gtgtgtgtaa agtctgaatt cctccagcag tcatcagtgt ccccacttcc
    25141 cagtcactgt aggagagtac cacgacccca cgtgacgtga cgcaacactt cgcgttacct
    25201 tgagtgggtc atccttgacg ctggcgtgac tgctgttgcc cccccttacc cgtgatcagg
    25261 tcttcaatga agggaaacaa ttgaagttac atatcaagct tcttctatac tgtatcttta
    25321 caaacgaacc tggcctccca ccatctatgg tggacctggg tactgcatct ctagtttttc
    25381 tgcaccccga cgtgactggt tccatcatcg gcatccgcca aaaagcgtcg ctaggtgtgt
    25441 catggatact gtaggagagg cactcaggct tcagaggcct tcttgggctt cctctcttcc
    25501 atcccgtatt cggtatccaa ctcactgcgc ataggtacct ctctcgccag ggtggcagcc
    25561 agcagtccca tgccagcaaa ggcaagcgag acgagccacg tctgacgcag gcttctggaa
    25621 aagacatttt tcatctgttc acttgcggca tcagacagcg ttccgaggaa ggctgaagtg
    25681 gcatgctcgt acgccttgcc tcccatgatg tcagccctga gcgccgggct attgatgagc
    25741 tcgggtgcca gctgatcaga gcgcgtgttg aacacggcag cggggatggc cgttccccaa
    25801 accatgccga agctgcggac gaacgaccac gtcgccgccc ccagagcggt atcggactcg
    25861 ctgagcggcg ccaggagtgc cgggagaagc gtcgggacca gcatgccggc tcccatggag
    25921 tacacgatct ggaagccgac ccatgccccg gtgctcgacc cactgtcgag gagggaaaac
    25981 agcccgaggc cgataagagt gacggcccag gaggcgtagt ggattggctt gtagcgaccc
    26041 atcttggtca tgagaaagcc gccgattcca gccgccggga ggatcgcgag gatggtggcc
    26101 agaatctgga cacctgagcg actaggcgag gagcccagga caccttggaa gtaaacgggc
    26161 atgaagtaga gctgccagat ggtgatgatg ccgtggaaga aggtcatgat catgacgccc
    26221 acggacgttc ggttgccgaa cagatgcaac ggaacagtcg ggttcggagc aaagcgagac
    26281 ccctcaaaga ccatgaacaa gcccatccca gcgatgccaa cgaagagcgg caccaagacg
    26341 cggaaggacg accacgcgta cacagaccca gcccacgaca gaccgatcag aaccgacgag
    26401 atggcggcga cgaagagggc gtttcccgcc cagtcaatgg tggaaatctt ggtcgccagg
    26461 ttggtctcct tctggtactt gaccttgagg aaggagaaca gggcgacaag cgcagcgccg
    26521 ccgaccggca gagcgaggta aaaggtccaa cgccaggtcg agtactgcac gatgagccca
    26581 gcaaagaacg gccccagcgc agtgcccagg aagatcatgc ccatgacaat ggccaggaac
    26641 ttgctgcgct ccctcagggg caccacgtcg cagatgatgg tctcggtgag cacggtggtg
    26701 ccgctggcgc cgatgccctg gaggatgcgt ccggcgatga gggtttcgat gttggttgca
    26761 ccgccgcaga taccgctgcc cagaacgaag agcgcggtcg ccccgagcat gggccagcgg
    26821 cgaccgaaga tgttggcgag ctgtccatac atgggctgca tcgcggtcct gatcgggaat
    26881 gttagttagt tcacagcttt tgaacttttt tttttcttct tctctttttt tggaggtcat
    26941 aacaagtcgg ggaaagagcg ccgtatagct tacatggcaa agagatatcc gttcacgacc
    27001 cagacgtaga gatgaccacc tccgaggtcg ttgacgatgg agggaagtgc agtggaggta
    27061 atggttccct ctagagcggt gagcagaccg gcaagactga tggagaccaa cagagcccag
    27121 aatctccagt ctctcttcgc cggggccaca ttcgtacgct cagtctcggg actctcagaa
    27181 gtagtagctg tttccagggg ggaatccacg gctgtaacgt tgcgggtctc gacgcctcgg
    27241 gttgagggat cgtgcatggt ttcagagctt ttgtcttcct gcaacatgtt ggctcgagga
    27301 tgcgttttcg ccctcttcct tgcgtatgct ggctggcccc cgaggtgagg tcgtcaggta
    27361 tgcggtcaga ggtctgcgat ggagaggagg atgagggagg tgtggatgtg cgcgtatcga
    27421 gaagctagtc tttaagtctc tggatgatat tctaaggtac agagacgaac gcccgtacat
    27481 tctcatctct tttcgcttgt tcattttggt ttcattttgg ttgtttgtcc ttcatggcca
    27541 cggcggagta gcggagttgg tggccggacc ctccgaacgg ggcactccat tcggcgcctg
    27601 ggaattgcca gattaggaaa ttcggatcct ccgatccaag tcgtagtcgc cggcctcacc
    27661 tcccgccttg tgaatcttga atcttgacca cctcctcctg ctcctcatct catgctcaag
    27721 ctcgagctcg agctcatgca gccacaccga tgggagaact gttcttccca ttctaattac
    27781 cacacttgac ctgctgcaag cccttcactc ataccacccc accatgtcat ccacaatgag
    27841 aggctgggtc cgccagcatc gtgggcccta cgagtcgtcc ctcaagctaa tcgactcgtt
    27901 acctgtccct cccgacccag gctctgactc cagcgacatc atcgttcgcg tttcttatgt
    27961 cgctcttgag ttctccatcg ctcacatcat gggcatcttt cccgctctgc cgtttgcgcc
    28021 ccctttggtc ccggagatat gtgtctctgg tacggtagca tccgccggtg gcaaggcgcc
    28081 cgaggagctg agacagcctg gcacgcaggt cctggccatg actgacccga tgagcatgat
    28141 gctcttcggc accggcgcgc tgaaagagta catgcgtctg cctgagcaat atgtcgtgcc
    28201 actcctacag cccagccact ctgtgaccac cgatcaccca catggcaccg ctgagcgtcc
    28261 ccaagctctc acactggccg agggcgcagg gctcatctct aatgggtcag cagcccaagc
    28321 cgtagtgcga gcggccaatg tcctttcggg tcagcgggtg ctcgtcaacg gggcgagtgg
    28381 aagtgtcggc cacatcgtct ctcaactttg ccgcgctcgc ggtgcctacg ttgtgggagt
    28441 tgcaagcggc gtcaatcaag attttgttcg tcgatacgga tgcaatgaag tatgcctccc
    28501 caccctccac cctctctctc cctctctttc ttgtttccct ttttgccagt aaggaggaag
    28561 tcgtgctaaa caaaaaaacc ccgtgtcttt ctttttgtac agtttgtcga ctacacgaaa
    28621 cacacggacc tgcccgagta tttggcttca acctacggat cgcagccttt cgactctata
    28681 ctagactgtg ttgggtcgca agacctttac gcgaattctc ccagatatct ccttcccggt
    28741 cggcctctgg tcaacatcgg cgctttcagc atgacggaca gcctgctgtc aacactatat
    28801 caatggtcca tgaacagctg gtgtccaacc tggcttgggg gtgtaccccg tccatacatc
    28861 cttttcagca acactcctga catgcaaggg gttctgagct tggtagagat ggtgcagcaa
    28921 ggaaagctca aggttcacat agactccgag ttcgaaatgg aagacctcat caaggcatat
    28981 gagcgcgtca cgagcaagag agcacgtggc aaggttctga ttcggattca ttagacatac
    29041 cacgacacag ccctgtggat aagtagatgc aactgctttc ttctgcacgg caacggcaga
    29101 tgatctactg cgtttcattc gctttaagtt ctttcttcta tatagtgccg caggtcatcc
    29161 caccttgtat tccaagtaaa ttcatcgttc cggccactct tctataggtc aaagatcctc
    29221 cttctgcccc cccccccccc cccccccccc cccccccccc cccccccccc cccccccccc
    29281 cccccccccc cccccccccc cccccnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    29341 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    29401 nnnnngactg ttcgcctaaa ccgagagtca agctcaagaa atgagggctg caccatggca
    29461 tccggcgcca atcaagcacg tcactggccc ccagttcaag gactcaatat actctcgaca
    29521 ctgcaaccgt gcagaaaggc cgtcagactc acacataatg ggtgagagca agttaagtcg
    29581 ggcattttta accccgagag ggggtctgga gagcactccc gttcggcaca gaagtcggga
    29641 catttttgtg tcctggagag gaagtcggaa gggtacgttc gggaaaagtc ccatccttcc
    29701 gatgtcgcca cgacatgcat acacggtaat acgcaaggag gccgagtcca gaaagagtca
    29761 tagaattgag ctttgagtcg ggaggcacgc aggctgagaa ggagggcatt tccgacgcag
    29821 tacggggtcg agagaccgaa gtccaagtgt tcgacattac gacctgcaga tctcggtctt
    29881 tatagaggct cgagtgcaga acagaaatct gtagtgcatg ataagttagt cgccgctgag
    29941 tgaatagtct gagatttgta ctatcatgtg ttcgactccc tattgtaagc tcatgtcttc
    30001 tcggcggtat ttttccccca catgctgtat gtattctgat gcgccgatcc cgaaatggaa
    30061 ctgcgtctga tcctacagac ttgaggcgcg cgcatcggcg gtttgctggt ccagttcttc
    30121 gtccttcaat actcccgaag actggtaaaa tgtaatacag aagcatcgcc catttcatag
    30181 gtcgcctacg gccttgtgcc attgtagtca gtatcgatac cccagcagtt tcttaccaag
    30241 ggcatcagca tccggcgacg tttctattgc actgtgatac cttaccacac gcaacaatct
    30301 atcgtcgaaa tctagttgaa agtcgcaggc caaaacactt gcgatctgac gaagcttgac
    30361 tccacccagc ccctggatca ccgagaagag aaacagcaag atctcctgta cgatggcgac
    30421 gcccggaaat gtcaccttca agaacaccca cgacagctgg gggatggtaa atgcgcctct
    30481 tccaccagga catattgccc aggttgcccc aaatgctaat caacgactcg gtagaattgg
    30541 ggtctctgcg actctagcga gcagatgctc accatgcaag gcatgccgtg gataatgcgc
    30601 aaactcgcca gctggatctc ggtcacggtc gtgatcaaga cgtggacgga tccggaaacg
    30661 ggggagacgc ggttcctcct gcagcacaac cctcccatgg gcttgccggg catgtccgag
    30721 gagcgggcgc tggattacgt gccggacgag ctgacagttc ccaaccttgg gaagcttcgc
    30781 gtgcgtacgc gttggggcac agccaaggag cttgatcagt tggacaagta cctggccaga
    30841 ggcttggaga aggggccgca ctcgatgatc catatgatga cggagcatct ggacattgac
    30901 gcggtgacgc accagatatt tgggtatgag gagatcgatg ggaccagata ccacgtcagg
    30961 cgtattgtgg tgcgcaaggg ccatgaggtg gcgaggctga ggctggtgta taactacctt
    31021 gggcctcgag ctggataatg acggctgttg tcgaggatga agtggtagaa atgatgaagg
    31081 gtagggaaat gcaaacacga tggcccattc tctgactctc gtgaccactg atgtcttctt
    31141 ttcccaattg acgagagaca gtcgacaaga agagaatcac gtttatgatt agccaattga
    31201 taagacacta tccgtaagaa ggtacaccgt acgtacagtt tggaattcga ggccatcgtg
    31261 gatccggtcc acttgcctag cgggcccagc ccatgctatt gacaggttgg ggtcgggaat
    31321 ctcgtccatg ggtgctttgt caaccgtccc gtccatctcc tgcatgatac accgtgggtg
    31381 ccgtttcaat gagggtcgtg gttcgtaaca caaagacggg catgatttca cggcgtgatc
    31441 gttttctcgg tggtttagga ggggggacgg attaaaatct ttccgggtgg cagtcgccca
    31501 aacttcagcg gctttgtctt ccagccgcca tgatctcaca cggtatgaca gttcagtcac
    31561 atcccatcac tccatccctc catccctcaa gtcacatatc atcatgcacc aacaacaacc
    31621 ccagcagcca tcgttttcaa agcgatgggc gtgcgaccga tgtcgagacc acaagttgcg
    31681 atgtctgaga acccaaggcc ggagcgaagg tccctgtgtc cgctgttcta gagctggtgc
    31741 atcatgcgtc acgggcgctc caatgccact cggtcgttct cgcgccagct ctgagaactc
    31801 acctcgcccg caggcctcca gaagaccacg gcactcggtc tttgtacctg tcacgctatc
    31861 cgggtctact cccctggcat ctgctagtat cgcagtcccc tcacatccag aacctgatgc
    31921 tgtcaccgag tcttctgggg cacatgcgca accatcacct ctcgacgggc tcgaatgctt
    31981 ccataaccac cttactgcag acgcgggaga gctcccaagc ctattcctcg acgacggagt
    32041 gcctggtggt cagggctcag atgctgctgt cgacaatgct ctggaatttg cattccccga
    32101 cgccgcagca gaagcaatgg atcttgtcaa cggccgagac catggacatt ttcccaactc
    32161 tctcggtctc tgcataggtc ccgatttcca acttcagtct ttttccggga acacccttga
    32221 cgttgctagt aggaccccgg aaccgtcaat cagctcaagc caaatcctgg cccgacttgc
    32281 tcatctcaac gaaggcatcg cccaccagct tgcatacatg gagagcctgg tcctgagcat
    32341 cccccctaca cacctcaccc cttcctgtgt cgacaaggtc ggggatcggc aggtcaatcc
    32401 catcctccgg gctctagaga gcacctctgc cctaaccgcc atcatcaagc agatcatctc
    32461 accagtccag gaccacggta cgttgcccgt caccacgcca gtcgtgctca tgtgcgtgtc
    32521 tggctacatt cagctgctgc agatctacaa ctccatgttt tgccacgttc accggtttct
    32581 cacgggtctg catgacatca gcagcttctt tgaggacttg ccgggcttcg cgaatatcag
    32641 cggcctgccg cccgtcaagg gggacctgta catcaaggtc gtcatccaag tagcccagca
    32701 caacatcggt agtcttgagc gagcaatcgg cctgccgcca gaattgt
//
