BGC0002239: GKK1032 A2 biosynthetic gene cluster from Acremonium sp.
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Location: 1 - 32,747 nt. (total: 32,747 nt).
This entry is originally from NCBI GenBank MW690134.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002239
Short description GKK1032 A2 biosynthetic gene cluster from Acremonium sp.
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
  • NRPS (Type I)
Loci
MW690134.1
via Heterologous expression
Compounds
  • GKK1032 A2
  • pyrrocidine A
  • pyrrocidine B
Species Acremonium sp. [taxonomy]
References
Chemical products information
GKK1032 A2 Evidence:
(no structure information available)
pyrrocidine A Evidence:
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Chemical database entries
PubCHEM
ChEMBL
pyrrocidine B Evidence:
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Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • QXF14596.1
  • pydG
 1104 - 2384 (-) PydG
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    • QXF14597.1
    • pydF
    		 4625 - 5944 (+) PydF
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      • QXF14599.1
      • pydZ
      		 6446 - 6820 (-) PydZ
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        • QXF14600.1
        • pydA
        		 7583 - 21059 (-) PydA
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          • QXF14598.1
          • pydX
          		 7607 - 8095 (+) PydX
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            • QXF14601.1
            • pydB
            		 21955 - 23253 (-) PydB
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              • QXF14602.1
              • pydC
              		 23726 - 24914 (+) PydC
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                • QXF14603.1
                • pydD
                		 25464 - 27287 (-) PydD
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                  • QXF14604.1
                  • pydE
                  		 27824 - 29034 (+) PydE
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                    • QXF14605.1
                    • pydY
                    		 30413 - 31038 (+) PydY
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                      Biosynthesis information

                      Biosynthetic modules

                      Name
                      Unk01
                      Type
                      nrps-type1
                      Genes
                      pydA
                      Substrates
                      tyrosine (evidence: Structure-based inference [2])
                      Integrated Monomers
                      Domains
                      adenylation
                      Annotation changelog

                      Entry version: 1

                      Date
                      Changes
                      Submitters
                      Reviewers
                      2022-09-15
                      Entry added
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      2022-09-15
                      Added NRP substrate specificities
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      Detailed domain annotation
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