BGC0002240 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002240 (Metarhizium anisopliae)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	11,531	BAB/BAA	PKS	100%

BGC0002240 - Region 1 - T1PKS

Download region GenBank file

Download region SVG

Location: 1 - 11,531 nt. (total: 11,531 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 11,532
Label		BGC0002240

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002240	1.00	Polyketide	BAB, BAA	Metarhizium anisopliae
BGC0002191	0.22	Polyketide	prolipyrone B, gibepyrone D	Fusarium graminearum PH-1
BGC0002596	0.21	Polyketide	lecanoric acid, orsellinic acid	Claviceps purpurea 20.1
BGC0002175	0.21	Polyketide	YWA1	Aspergillus oryzae RIB40
BGC0000107	0.21	Polyketide	naphthopyrone	Aspergillus nidulans FGSC A4
BGC0001257	0.21	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Nodulisporium sp. ATCC74245
BGC0001258	0.21	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Glarea lozoyensis
BGC0001254	0.20	Polyketide	ACT-Toxin II	Alternaria alternata
BGC0002192	0.19	Polyketide	FR901512	fungal sp. No.14919
BGC0002155	0.19	Polyketide	nectriapyrone C, nectriapyrone D, nectriapyrone	Pyricularia oryzae 70-15

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002240	1.00	Polyketide	BAB, BAA	Metarhizium anisopliae
BGC0002191	0.54	Polyketide	prolipyrone B, gibepyrone D	Fusarium graminearum PH-1
BGC0002596	0.54	Polyketide	lecanoric acid, orsellinic acid	Claviceps purpurea 20.1
BGC0002175	0.54	Polyketide	YWA1	Aspergillus oryzae RIB40
BGC0000107	0.53	Polyketide	naphthopyrone	Aspergillus nidulans FGSC A4
BGC0001257	0.53	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Nodulisporium sp. ATCC74245
BGC0001258	0.53	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Glarea lozoyensis
BGC0001254	0.53	Polyketide	ACT-Toxin II	Alternaria alternata
BGC0002192	0.52	Polyketide	FR901512	fungal sp. No.14919
BGC0002155	0.51	Polyketide	nectriapyrone C, nectriapyrone D, nectriapyrone	Pyricularia oryzae 70-15

Similar known gene clusters from MIBiG 4.0

Module view

Legend

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 11531:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

MANI_025650

PKS_AT (627..956): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 70.8%; Methylmalonyl-CoA: 62.5%; Ethylmalonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 92.7
Isobutyryl-CoA: 78.3
Malonyl-CoA: 73.7
Methoxymalonyl-CoA: 73.0
Propionyl-CoA: 44.1
2-Methylbutyryl-CoA: 38.2
Acetyl-CoA: 31.0
fatty_acid: 29.5
Benzoyl-CoA: 27.8
CHC-CoA: 27.1
trans-1,2-CPDA: 22.9
inactive: 18.5
3-Methylbutyryl-CoA: 17.3
Ethylmalonyl-CoA: -4.0