LOCUS       BGC0002242             23805 bp    DNA     linear   PLN 31-DEC-2014
DEFINITION  Aspergillus ustus strain 3.3904 AUSC_58, whole genome shotgun
            sequence.
ACCESSION   BGC0002242
VERSION     BGC0002242
KEYWORDS    .
SOURCE      Aspergillus ustus
  ORGANISM  Aspergillus ustus
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus.
COMMENT     The only annotation on JOMC01000000 are predicted secondary
            metabolite biosynthetic gene clusters on 44 contigs.
            ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 17:11:43
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23805
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[7071:18848]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      7072..18848
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..23805
                     /SMILES="NC([*])C(=O)NC([*])C(=O)NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..23805
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0002242"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..23805
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            983..2581
                     /locus_tag="HK57_00501"
     mRNA            join(983..1148,1199..1785,1847..2190,2240..2466,2526..2581)
                     /locus_tag="HK57_00501"
                     /note="AUSM36_001"
                     /product="MAK1-like monooxygenase"
     CDS             join(983..1148,1199..1785,1847..2190,2240..2466,2526..2581)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087:hypothetical
                     protein (Score: 195.5; E-value: 2.8e-59)"
                     /gene_kind="other"
                     /locus_tag="HK57_00501"
                     /note="AUSM36_001"
                     /product="MAK1-like monooxygenase"
                     /protein_id="KIA75686.1"
                     /transl_table=11
                     /translation="MLDPRIAAAPQSSGITVIIVGLGIAGLTTAISCHLRGHTVIGFDK
                     LENLEPYGGLGDGVTLAPNGTRVLREFGNGTVAEWMERWALTCTNCKVFDTSGNHIGQH
                     PIPETDRGLALVPRGKLVQTLYEVAQELGLDLRLGVKITEYYEDHEHASVVVDGTRFKG
                     DCILFADGANSKHRKIVSTRNVELHQSGFSVYRGKVEGEVVKKDPKCHWLLSGEMEKDV
                     AKAFSGPNMYLVLATCGSGKACFCIAMSQNTRPLENAWTTPIDKEEVLKRVRGWKLEHQ
                     IRPIIEHMSKDQLINTPLVRAGALDSWVSPTGRIALIGDAAHPFFPTSAQGASQAIEDG
                     ATVAITLQLAGKRNIKLGLNAMMELRKHRATYIQHNAWRVNDEWFRSDQEERTGDKASP
                     TPGVMDWIIDHCCQTYAWDEFDQVRECIETGIPYHPSNLPAECYEKATNFLEQGGHGLP
                     F"
     gene            complement(3213..5312)
                     /locus_tag="HK57_00502"
     mRNA            complement(join(3213..3387,3467..3627,3705..3815,
                     3883..4206,4267..4358,4418..4532,4610..4871,4943..5006,
                     5048..5312))
                     /locus_tag="HK57_00502"
                     /note="AUSM36_002"
                     /product="hypothetical protein"
     CDS             complement(join(3213..3387,3467..3627,3705..3815,
                     3883..4206,4267..4358,4418..4532,4610..4871,4943..5006,
                     5048..5312))
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 298.5; E-value: 1.5e-90)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="HK57_00502"
                     /note="AUSM36_002"
                     /product="hypothetical protein"
                     /protein_id="KIA75687.1"
                     /sec_met_domain="p450 (E-value: 1.6e-65, bitscore: 209.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVAMESYYPSSNVQIMFTSLAVGILVAGLVHQAFSRLISHPLSKI
                     PGPYLAGWSNCYGFYHDVIRSGNYIKHIEKLHEIYSAILTVPAQSPVIRTGPNEVHVND
                     PEVYKEVFKIASPFLKTQMFSTAVGLAQAIGTIIDPKEHHVRRSILGPRFAPKVIASYT
                     PKLLGQVRLCCNVMVTKARQGRTIILPRHTRSLTVDVITEFTFGRSFGLTSSAEEEPEL
                     LKDLALFTAHFHVCKYIPLWRWFVVNIPERISRKLMPGYFQLRRKATDELEEIIADKKA
                     GKAISLDDTVVDLLLQPHPKKGHRIPSVSALVDEGCAFILGGSDTTGYTMETATYAILA
                     YPGVFKRLREELDGAASYIRGQYDLVRVEQLPFLTAIIKESLRLYTPTPAPLPRTVPAG
                     GYEVDGYFLPGGTILSHSIYLIHHNPQCFSDPKQFRPERWLGEEGQALEQYYIPFSRGT
                     RSCIGTSLAYHEMYSFLAILFSRFDLELVDTNAESMEWTDQMFARRKADVKIRLVRDRW
                     SGEVF"
     gene            7072..18848
                     /locus_tag="HK57_00503"
     mRNA            join(7072..7497,7557..18848)
                     /locus_tag="HK57_00503"
                     /note="AUSM36_003"
                     /product="nonribosomal peptide synthase"
     CDS             join(7072..7497,7557..18848)
                     /NRPS_PKS="Domain: AMP-binding (229-622). E-value: 1.3e-81.
                     Score: 266.2. Matches aSDomain:
                     nrpspksdomains_HK57_00503_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (768-835). E-value: 5e-12. Score:
                     37.8. Matches aSDomain: nrpspksdomains_HK57_00503_PCP.1"
                     /NRPS_PKS="Domain: Condensation_DCL (875-1147). E-value:
                     9.6e-32. Score: 102.1. Matches aSDomain:
                     nrpspksdomains_HK57_00503_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1312-1708). E-value: 2e-82.
                     Score: 268.8. Matches aSDomain:
                     nrpspksdomains_HK57_00503_AMP-binding.2"
                     /NRPS_PKS="Domain: PP-binding (1854-1920). E-value:
                     4.8e-13. Score: 41.4. Matches aSDomain:
                     nrpspksdomains_HK57_00503_PP-binding.1"
                     /NRPS_PKS="Domain: Epimerization (1941-2229). E-value:
                     1.7e-28. Score: 90.5. Matches aSDomain:
                     nrpspksdomains_HK57_00503_Epimerization.1"
                     /NRPS_PKS="Domain: Condensation_DCL (2404-2692). E-value:
                     3.1e-40. Score: 130.0. Matches aSDomain:
                     nrpspksdomains_HK57_00503_Condensation_DCL.2"
                     /NRPS_PKS="Domain: AMP-binding (2852-3250). E-value:
                     1.6e-83. Score: 272.4. Matches aSDomain:
                     nrpspksdomains_HK57_00503_AMP-binding.3"
                     /NRPS_PKS="Domain: PCP (3386-3454). E-value: 4.9e-19.
                     Score: 60.2. Matches aSDomain:
                     nrpspksdomains_HK57_00503_PCP.2"
                     /NRPS_PKS="Domain: Condensation_DCL (3514-3768). E-value:
                     9.6e-34. Score: 108.7. Matches aSDomain:
                     nrpspksdomains_HK57_00503_Condensation_DCL.3"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     265.8; E-value: 1e-80)"
                     /gene_kind="biosynthetic"
                     /locus_tag="HK57_00503"
                     /note="AUSM36_003"
                     /product="nonribosomal peptide synthase"
                     /protein_id="KIA75688.1"
                     /sec_met_domain="Condensation (E-value: 5.9e-40, bitscore:
                     125.2, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 3.5e-96, bitscore:
                     310.3, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.4e-16, bitscore:
                     48.3, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAIEDAAKPDEPTWVCLFPRLTGEPPGKGTRETTHFDPMTNSLLD
                     KCSKQFHVAPHLVLAAVWAAVLRQYTEMDNPGFVMVQPSREGHNNYTAEGYSTQLDHDA
                     IVQKYMRDTSWERFSLVQGTYMYNTALVIGDEQDLPTESVDISIMLQLEQQPPALSLAY
                     TTQVVSTVFAEVVASAISQSIYHLQREPNVLLKDLDLSSPLSAEMVRSWQGCASISTKH
                     DFMFEVIARQAAQRPNAVAVDAWDVRWTYQELEKASSQLAFQLQTRGVGTGVQVLMCFE
                     KTGYAVLAMLAVNKTGGSFVPCDPSYPAERRRQILRRIHASVALTSPECGDLFSDETGL
                     DVVTVPGCAMAPSIPKTVPKSCLSPTSPAYILYTSGSTGEPKGCEITHAAFASIAEHAE
                     ALQLSPTTRSLQFASFSFGMAIIEIFCTLAAGGVVCMLSADQRSNSLAHTMTEMKVNWA
                     FMTPTVLSSLQPQDLPYLHDLFIAGEAMSEGHVRTWGSSVHVHQAYGLTEWSGIFAISD
                     RMTVSHERATIGRPVNGLGWLVDPLNQDRLVPVGAPGELVISGPSLASGYFEDPRRSKA
                     SFISPAWRRTSTDVEDRLYRTGDIMRYSMDGTLQYIRRKDSQVKIRGLRVELGEVESNL
                     LPLIPEAKRVIATVWRPLEDSHQQLLVAFVLLRVSDATTIPLVRGAHACELQILDLTPA
                     QSQGLRDAHHTLRSQLPGYMIPQHLIPVAAVPTTYTGKVDRRKLGALLNKISPSYLSQL
                     AGQRSEYQQPANEREQLIHDMTCSILGLKSASMQDNFFNISGDSVAAMKMVRLASSNKV
                     SLTVAKIFKYPVLKDMAAQIGQRNDEPAANPVGRFGLLLNATPTDVMREVAEQTHLDVA
                     QVLNAYPCTPLQEGLCALSVRDQRAYKARIVCQVEPSVDISAVRQAWERIFEMNDILRT
                     RLVASSSHGTIQAVMQENFQWDYAENLDEYSARVSKEPMGIGHRLVRACLLADPRTKTG
                     PATLVLTLHHAICDRWSVGLLLEQLERQLGLTTKPVLEHHEFLPFIEHLADLASKHQEY
                     WNSQFHGIEAQIFPELPSPYYDPVVNQTLTTQVVLPERNLRDKTVASHVRLALALAIAH
                     HTCSDDIIFGATVSGRAALMSGIERMSGPTIATIPLRIALNRENTVAQSLSAIQAQSIE
                     TIPFEQAGLQNIRKYSSESDYACKFQTHLTIQPALCESFALLNVIEQGPATPGGFASYA
                     LCLECYLEGDEKRMKVMAAFDSNVISSPRVARFINHLEFVLHEIMKNPDQLLSSVSHIN
                     PSDMSQLWEWNTTLASKPKLQDSVHKVVQERAHETPAATAICAHDRIFTYRDLETRATH
                     LAGELLRRGVRRRTLVPLLFEKSAWAIVSMLAVIKAGAGIVALDPSYPLGRSQAICEQV
                     GSSFALCSKGLAITTQKLGCQPVVVSEEAPIWGHTIEAEELPPVGPSDILYLIFTSGST
                     GAPKGVIVEHGCFASSTAAYSPEIKLRSDSRMLQFCSFAFDCCFVEIFGTLMTGGCLCV
                     PSDQDRTNNIHNAIRELQISHAVLTPSVARLVQLEPIPSLKVLMLAGEPVSASDVEYWS
                     SRVYLVNGYGPSECAPISATQHNDGSNGIHARDIGRTTGCIGWVCDPRDHGILVPIGAT
                     GELILEGPNVGPGYFKNPSETESAFINSPPWLRALRKNTSRVYKTKDLVRYTEDGRLQY
                     VGRIGHQVKIRGQRLDPSHVESQLLQHFGGAIKVAAVVATPGNANNSSSRAVLVGFILT
                     DEDQTQESRVGDAVCAPASDSFSRRATSARLKLQKSLPEFMVPSLLIPLRFMPQTPSGK
                     LDRLRLRQEITSRTWKELMQHETASGGESVEMPSTDAERELQMIWSRVLSIPPENVGVN
                     QPFLTCGGDSITAMLVVTQARRGRLGLNITVDDIFNLHTISRLADHAATTSVPYQLSAN
                     GVGIAVDVPFPLSPIQHLFFSKNPQGSNRFSHNILLHLEQPVTLELLRHAGQNLAEKHP
                     MLRARFSRDASGQWHQFVHGDVQGSVACRIHRLRTKSSVRRILAQSREGLDILAGPVFS
                     LDLIQIDGRQSIFALAHHLVIDMVSWPVLLADLEVSLRGGSVQSLPSTSYQTWCRILAE
                     STSSLSLPPVESIDSKEITSFWGVSDNLNVIGLTSEKVLNIDGTITNAVLGKANDAFGT
                     QPVELIHAAILHAFITTFPSRKAPAIYSEGHGREPGEDTTVDITSTVGWFTSIAPVCVQ
                     PKGPACDLSMVVRQVKDARRQSPRNGLEAFTANYYNSNNMQVDPAHTMEITFNYGGRYH
                     QQLEQTCDLFSIEPLQNLGIFDAAHSVARWSFVDINAFVHDEELNLAFTFPKGCSQAQV
                     LGPWMNNIRNALRRMASEFVEYPRSFTMTDFSCLNLSYEELDALRSRLTVAGIHPENVE
                     DIYPCAPIQRGILLSRARNPDLYHIAMTWVVKPPYSSAPPSAERARSAITQVIARHAFL
                     RTYFTVTESEDSMYDQVVVREMRPEIPVTYSEKSAQQALSKADETFRPSTECPYRFSIL
                     VSGDKRVYIRLDITHALVDAHTLEILERELCLAYDGKLGVDKAPCYSSYISFLRSQDRE
                     ADRGFWQQYLAGSQSCLFPALTGHCAKEPDSHRDLVFEIGNVDRLRTYCKSRSVTVANV
                     FSLAWALILRAYVGETDVCFGFLVSGRELPFAGASDVGGPLINMLTTRLRLAGDARLCE
                     LLQGVQADFLACRRHQTYPIGDIIHDQGSSESFKVNTALSVQRVLEDETPSTGTAMSLV
                     HRQDPSEYAIAMNVEIEKDRIVCHFRYWLSNLSDAQASLVASSFDQAVSQIVSNDQATP
                     SEVNLLSPHHRDLIWNWNGSLASPGPACVHEIIRQRVVESPSSPAVVTTEGALSYGTLE
                     TLSDRLAHYLVQIGVVSEMIVPCCFDKGTWTVVAVLAVLKAGGAFALMDTMQPDHRLES
                     ICADANSPIILASVRQAPRCAKFGKKVVAIGGNDDDRWNRPLLRSKHFVHQQQPNSKNA
                     MFVVYTSGSTGKPKGVIIEHGSFHAMIQAQSPLWYMTATARLMQFASYAFDASVLEMLL
                     PLMLGATTCILTEVERRDHLRESIVQLGVTHAFLTPSVARLLSPAMVPNLAVLICVGEP
                     MTQLDLDEWANDVRLINAYGPAECTIGAITQPIVTTTSRPGDIGRPAGCAAWVVDLENS
                     QCLVPIGAVGELIIEGPTVGRGYLNNPQATAAAFLSRPSWLRDLRGDTRIYKTGDLVRY
                     GPDGQLYISGRKDTQVKIRGQRIELGEIEYQVHCAFKDVQDVIVEMVLVGPEDNKTPTL
                     FALISGSHIGPMGDDPFLVPDETFKLQASSASASLFQKLPAYMVPSYFIPLSAIPVGPS
                     GKADRKQLRRFLANLQGEQLKMYRPTGGSQRTVTSVQERVLHGIWCNVLGVELEDIGSD
                     DNFFQIGGDSVNAMRVAAMARKASLNISVADIFAHPKLSSLSRLASTIATEHFEPVPFS
                     LNPVSEMDGFNLFLQTRRGIPACAKIVDILPTSAAQAFFLERPTLHHFAFAIEGSVDVE
                     KLHKACAAVYQSFSLLRTLFLKHQDQTVQVILDDVPVPFHHFVTDQPPARLLEVIRDAD
                     RENMPLYGQLPFAFILISHRDSLNHSLVCRAAHPQWDGLSVGQLFKSISDAYLGIDLIP
                     TTPLSTLVHYRLRQQTVDPSLRFWRNYLRGATITRLTQLPPHKDLSQGTTIWENTNMRP
                     SPLAPKGITMASVVKAAWALVLSQESKTNDIVFGQTVNGRNAPLPDIDMILGCCLNFAP
                     VRIRLDQIGSISDLLSLVQNQYQQTVQHDEIELPTIIERCTPWARETDLHSIVQHQNIP
                     LTHDLSLGRGLKTQFSLNGYFRPGKEVFIFTEPMGDILSVQLCVNPNVIGLERASGLHR
                     RLVKLIGDLCYLDGGEAVEKLLKVV"
     aSDomain        7818..8996
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HK57_00503_AMP-binding.1"
                     /evalue="1.30E-81"
                     /label="HK57_00503_AMP-binding.1"
                     /locus_tag="HK57_00503"
                     /protein_end="622"
                     /protein_start="229"
                     /score="266.2"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="ARQAAQRPNAVAVDAWDVRWTYQELEKASSQLAFQLQTRGVGTGV
                     QVLMCFEKTGYAVLAMLAVNKTGGSFVPCDPSYPAERRRQILRRIHASVALTSPECGDL
                     FSDETGLDVVTVPGCAMAPSIPKTVPKSCLSPTSPAYILYTSGSTGEPKGCEITHAAFA
                     SIAEHAEALQLSPTTRSLQFASFSFGMAIIEIFCTLAAGGVVCMLSADQRSNSLAHTMT
                     EMKVNWAFMTPTVLSSLQPQDLPYLHDLFIAGEAMSEGHVRTWGSSVHVHQAYGLTEWS
                     GIFAISDRMTVSHERATIGRPVNGLGWLVDPLNQDRLVPVGAPGELVISGPSLASGYFE
                     DPRRSKASFISPAWRRTSTDVEDRLYRTGDIMRYSMDGTLQYIRRKDSQVKIR"
     aSModule        7818..9635
                     /complete
                     /domains="nrpspksdomains_HK57_00503_AMP-binding.1"
                     /domains="nrpspksdomains_HK57_00503_PCP.1"
                     /locus_tags="HK57_00503"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       8001..8042
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HK57_00503_0001"
                     /evalue="9.20E-02"
                     /label="NRPS-A_a2"
                     /locus_tag="HK57_00503"
                     /protein_end="304"
                     /protein_start="290"
                     /score="6.7"
                     /tool="antismash"
                     /translation="LAVNKTGGSFVPCD"
     CDS_motif       8235..8294
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HK57_00503_0002"
                     /evalue="1.00E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="HK57_00503"
                     /protein_end="388"
                     /protein_start="368"
                     /score="27.3"
                     /tool="antismash"
                     /translation="AYILYTSGSTGEPKGCEITH"
     CDS_motif       8775..8864
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HK57_00503_0003"
                     /evalue="7.60E-11"
                     /label="NRPS-A_a6"
                     /locus_tag="HK57_00503"
                     /protein_end="578"
                     /protein_start="548"
                     /score="34.3"
                     /tool="antismash"
                     /translation="PVGAPGELVISGPSLASGYFEDPRRSKASF"
     CDS_motif       8961..9026
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HK57_00503_0004"
                     /evalue="2.70E-09"
                     /label="NRPS-A_a8"
                     /locus_tag="HK57_00503"
                     /protein_end="632"
                     /protein_start="610"
                     /score="29.2"
                     /tool="antismash"
                     /translation="YIRRKDSQVKIRGLRVELGEVE"
     aSDomain        9435..9635
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HK57_00503_PCP.1"
                     /evalue="5.00E-12"
                     /label="HK57_00503_PCP.1"
                     /locus_tag="HK57_00503"
                     /protein_end="835"
                     /protein_start="768"
                     /score="37.8"
                     /tool="antismash"
                     /translation="QLIHDMTCSILGLKSASMQDNFFNISGDSVAAMKMVRLASSNKVS
                     LTVAKIFKYPVLKDMAAQIGQR"
     aSDomain        9756..10571
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HK57_00503_Condensation_DCL.1"
                     /domain_subtypes="Condensation_DCL"
                     /evalue="9.60E-32"
                     /label="HK57_00503_Condensation_DCL.1"
                     /locus_tag="HK57_00503"
                     /protein_end="1147"
                     /protein_start="875"
                     /score="102.1"
                     /tool="antismash"
                     /translation="AYPCTPLQEGLCALSVRDQRAYKARIVCQVEPSVDISAVRQAWER
                     IFEMNDILRTRLVASSSHGTIQAVMQENFQWDYAENLDEYSARVSKEPMGIGHRLVRAC
                     LLADPRTKTGPATLVLTLHHAICDRWSVGLLLEQLERQLGLTTKPVLEHHEFLPFIEHL
                     ADLASKHQEYWNSQFHGIEAQIFPELPSPYYDPVVNQTLTTQVVLPERNLRDKTVASHV
                     RLALALAIAHHTCSDDIIFGATVSGRAALMSGIERMSGPTIATIPLRIAL"
     aSModule        9756..13817
                     /complete
                     /domains="nrpspksdomains_HK57_00503_Condensation_DCL.1"
                     /domains="nrpspksdomains_HK57_00503_AMP-binding.2"
                     /domains="nrpspksdomains_HK57_00503_PP-binding.1"
                     /domains="nrpspksdomains_HK57_00503_Epimerization.1"
                     /locus_tags="HK57_00503"
                     /monomer_pairings="X -> D-X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       9816..9929
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HK57_00503_0005"
                     /evalue="4.00E-07"
                     /label="C2_DCL_024-062"
                     /locus_tag="HK57_00503"
                     /protein_end="933"
                     /protein_start="895"
                     /score="22.3"
                     /tool="antismash"
                     /translation="AYKARIVCQVEPSVDISAVRQAWERIFEMNDILRTRLV"
     CDS_motif       10119..10172
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HK57_00503_0006"
                     /evalue="5.10E-05"
                     /label="C3_LCL_132-143"
                     /locus_tag="HK57_00503"
                     /protein_end="1014"
                     /protein_start="996"
                     /score="16.0"
                     /tool="antismash"
                     /translation="LHHAICDRWSVGLLLEQL"
     CDS_motif       10467..10562
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HK57_00503_0007"
                     /evalue="1.30E-12"
                     /label="C5_DCL_263-294"
                     /locus_tag="HK57_00503"
                     /protein_end="1144"
                     /protein_start="1112"
                     /score="40.2"
                     /tool="antismash"
                     /translation="DIIFGATVSGRAALMSGIERMSGPTIATIPLR"
     aSDomain        11067..12254
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HK57_00503_AMP-binding.2"
                     /evalue="2.00E-82"
                     /label="HK57_00503_AMP-binding.2"
                     /locus_tag="HK57_00503"
                     /protein_end="1708"
                     /protein_start="1312"
                     /score="268.8"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="QERAHETPAATAICAHDRIFTYRDLETRATHLAGELLRRGVRRRT
                     LVPLLFEKSAWAIVSMLAVIKAGAGIVALDPSYPLGRSQAICEQVGSSFALCSKGLAIT
                     TQKLGCQPVVVSEEAPIWGHTIEAEELPPVGPSDILYLIFTSGSTGAPKGVIVEHGCFA
                     SSTAAYSPEIKLRSDSRMLQFCSFAFDCCFVEIFGTLMTGGCLCVPSDQDRTNNIHNAI
                     RELQISHAVLTPSVARLVQLEPIPSLKVLMLAGEPVSASDVEYWSSRVYLVNGYGPSEC
                     APISATQHNDGSNGIHARDIGRTTGCIGWVCDPRDHGILVPIGATGELILEGPNVGPGY
                     FKNPSETESAFINSPPWLRALRKNTSRVYKTKDLVRYTEDGRLQYVGRIGHQVKIR"
     CDS_motif       11250..11291
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HK57_00503_0008"
                     /evalue="2.80E-01"
                     /label="NRPS-A_a2"
                     /locus_tag="HK57_00503"
                     /protein_end="1387"
                     /protein_start="1373"
                     /score="5.3"
                     /tool="antismash"
                     /translation="LAVIKAGAGIVALD"
     CDS_motif       11487..11543
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HK57_00503_0009"
                     /evalue="1.70E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="HK57_00503"
                     /protein_end="1471"
                     /protein_start="1452"
                     /score="26.6"
                     /tool="antismash"
                     /translation="YLIFTSGSTGAPKGVIVEH"
     CDS_motif       11892..11915
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HK57_00503_0010"
                     /evalue="1.60E+00"
                     /label="NRPS-A_a5"
                     /locus_tag="HK57_00503"
                     /protein_end="1595"
                     /protein_start="1587"
                     /score="2.6"
                     /tool="antismash"
                     /translation="YGPSECAP"
     CDS_motif       12030..12119
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HK57_00503_0011"
                     /evalue="3.40E-09"
                     /label="NRPS-A_a6"
                     /locus_tag="HK57_00503"
                     /protein_end="1663"
                     /protein_start="1633"
                     /score="29.0"
                     /tool="antismash"
                     /translation="PIGATGELILEGPNVGPGYFKNPSETESAF"
     CDS_motif       12219..12284
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HK57_00503_0012"
                     /evalue="1.10E-06"
                     /label="NRPS-A_a8"
                     /locus_tag="HK57_00503"
                     /protein_end="1718"
                     /protein_start="1696"
                     /score="21.2"
                     /tool="antismash"
                     /translation="YVGRIGHQVKIRGQRLDPSHVE"
     aSDomain        12693..12890
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HK57_00503_PP-binding.1"
                     /evalue="4.80E-13"
                     /label="HK57_00503_PP-binding.1"
                     /locus_tag="HK57_00503"
                     /protein_end="1920"
                     /protein_start="1854"
                     /score="41.4"
                     /tool="antismash"
                     /translation="ELQMIWSRVLSIPPENVGVNQPFLTCGGDSITAMLVVTQARRGRL
                     GLNITVDDIFNLHTISRLADH"
     aSDomain        12954..13817
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HK57_00503_Epimerization.1"
                     /evalue="1.70E-28"
                     /label="HK57_00503_Epimerization.1"
                     /locus_tag="HK57_00503"
                     /protein_end="2229"
                     /protein_start="1941"
                     /score="90.5"
                     /tool="antismash"
                     /translation="PFPLSPIQHLFFSKNPQGSNRFSHNILLHLEQPVTLELLRHAGQN
                     LAEKHPMLRARFSRDASGQWHQFVHGDVQGSVACRIHRLRTKSSVRRILAQSREGLDIL
                     AGPVFSLDLIQIDGRQSIFALAHHLVIDMVSWPVLLADLEVSLRGGSVQSLPSTSYQTW
                     CRILAESTSSLSLPPVESIDSKEITSFWGVSDNLNVIGLTSEKVLNIDGTITNAVLGKA
                     NDAFGTQPVELIHAAILHAFITTFPSRKAPAIYSEGHGREPGEDTTVDITSTVGWFTSI
                     APVCVQP"
     CDS_motif       13035..13124
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HK57_00503_0013"
                     /evalue="1.30E-05"
                     /label="C2_DCL_024-062"
                     /locus_tag="HK57_00503"
                     /protein_end="1998"
                     /protein_start="1968"
                     /score="17.5"
                     /tool="antismash"
                     /translation="LHLEQPVTLELLRHAGQNLAEKHPMLRARF"
     CDS_motif       13320..13382
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HK57_00503_0014"
                     /evalue="5.60E-08"
                     /label="NRPS-E2"
                     /locus_tag="HK57_00503"
                     /protein_end="2084"
                     /protein_start="2063"
                     /score="25.2"
                     /tool="antismash"
                     /translation="FALAHHLVIDMVSWPVLLADL"
     CDS_motif       13761..13811
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HK57_00503_0015"
                     /evalue="1.80E-06"
                     /label="NRPS-E5"
                     /locus_tag="HK57_00503"
                     /protein_end="2227"
                     /protein_start="2210"
                     /score="20.2"
                     /tool="antismash"
                     /translation="DITSTVGWFTSIAPVCV"
     aSDomain        14343..15206
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HK57_00503_Condensation_DCL.2"
                     /domain_subtypes="Condensation_DCL"
                     /evalue="3.10E-40"
                     /label="HK57_00503_Condensation_DCL.2"
                     /locus_tag="HK57_00503"
                     /protein_end="2692"
                     /protein_start="2404"
                     /score="130.0"
                     /tool="antismash"
                     /translation="EDIYPCAPIQRGILLSRARNPDLYHIAMTWVVKPPYSSAPPSAER
                     ARSAITQVIARHAFLRTYFTVTESEDSMYDQVVVREMRPEIPVTYSEKSAQQALSKADE
                     TFRPSTECPYRFSILVSGDKRVYIRLDITHALVDAHTLEILERELCLAYDGKLGVDKAP
                     CYSSYISFLRSQDREADRGFWQQYLAGSQSCLFPALTGHCAKEPDSHRDLVFEIGNVDR
                     LRTYCKSRSVTVANVFSLAWALILRAYVGETDVCFGFLVSGRELPFAGASDVGGPLINM
                     LTTRLRL"
     aSModule        14343..17492
                     /complete
                     /domains="nrpspksdomains_HK57_00503_Condensation_DCL.2"
                     /domains="nrpspksdomains_HK57_00503_AMP-binding.3"
                     /domains="nrpspksdomains_HK57_00503_PCP.2"
                     /locus_tags="HK57_00503"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       14472..14534
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HK57_00503_0016"
                     /evalue="1.20E-03"
                     /label="C2_dual_024-063"
                     /locus_tag="HK57_00503"
                     /protein_end="2468"
                     /protein_start="2447"
                     /score="11.4"
                     /tool="antismash"
                     /translation="ERARSAITQVIARHAFLRTYF"
     CDS_motif       14742..14801
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HK57_00503_0017"
                     /evalue="3.70E+00"
                     /label="C3_DCL_135-156"
                     /locus_tag="HK57_00503"
                     /protein_end="2557"
                     /protein_start="2537"
                     /score="0.5"
                     /tool="antismash"
                     /translation="HALVDAHTLEILERELCLAY"
     CDS_motif       15102..15191
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HK57_00503_0018"
                     /evalue="4.30E-06"
                     /label="C5_DCL_263-294"
                     /locus_tag="HK57_00503"
                     /protein_end="2687"
                     /protein_start="2657"
                     /score="19.2"
                     /tool="antismash"
                     /translation="DVCFGFLVSGRELPFAGASDVGGPLINMLT"
     aSDomain        15687..16880
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HK57_00503_AMP-binding.3"
                     /evalue="1.60E-83"
                     /label="HK57_00503_AMP-binding.3"
                     /locus_tag="HK57_00503"
                     /protein_end="3250"
                     /protein_start="2852"
                     /score="272.4"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="QRVVESPSSPAVVTTEGALSYGTLETLSDRLAHYLVQIGVVSEMI
                     VPCCFDKGTWTVVAVLAVLKAGGAFALMDTMQPDHRLESICADANSPIILASVRQAPRC
                     AKFGKKVVAIGGNDDDRWNRPLLRSKHFVHQQQPNSKNAMFVVYTSGSTGKPKGVIIEH
                     GSFHAMIQAQSPLWYMTATARLMQFASYAFDASVLEMLLPLMLGATTCILTEVERRDHL
                     RESIVQLGVTHAFLTPSVARLLSPAMVPNLAVLICVGEPMTQLDLDEWANDVRLINAYG
                     PAECTIGAITQPIVTTTSRPGDIGRPAGCAAWVVDLENSQCLVPIGAVGELIIEGPTVG
                     RGYLNNPQATAAAFLSRPSWLRDLRGDTRIYKTGDLVRYGPDGQLYISGRKDTQVKIR"
     CDS_motif       15867..15908
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HK57_00503_0019"
                     /evalue="2.60E-02"
                     /label="NRPS-A_a2"
                     /locus_tag="HK57_00503"
                     /protein_end="2926"
                     /protein_start="2912"
                     /score="8.4"
                     /tool="antismash"
                     /translation="LAVLKAGGAFALMD"
     CDS_motif       16119..16175
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HK57_00503_0020"
                     /evalue="1.30E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="HK57_00503"
                     /protein_end="3015"
                     /protein_start="2996"
                     /score="27.0"
                     /tool="antismash"
                     /translation="FVVYTSGSTGKPKGVIIEH"
     CDS_motif       16524..16547
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HK57_00503_0021"
                     /evalue="1.90E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="HK57_00503"
                     /protein_end="3139"
                     /protein_start="3131"
                     /score="5.2"
                     /tool="antismash"
                     /translation="YGPAECTI"
     CDS_motif       16659..16748
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HK57_00503_0022"
                     /evalue="1.10E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="HK57_00503"
                     /protein_end="3206"
                     /protein_start="3176"
                     /score="46.5"
                     /tool="antismash"
                     /translation="PIGAVGELIIEGPTVGRGYLNNPQATAAAF"
     CDS_motif       16851..16910
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HK57_00503_0023"
                     /evalue="3.70E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="HK57_00503"
                     /protein_end="3260"
                     /protein_start="3240"
                     /score="35.0"
                     /tool="antismash"
                     /translation="GRKDTQVKIRGQRIELGEIE"
     aSDomain        17289..17492
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HK57_00503_PCP.2"
                     /evalue="4.90E-19"
                     /label="HK57_00503_PCP.2"
                     /locus_tag="HK57_00503"
                     /protein_end="3454"
                     /protein_start="3386"
                     /score="60.2"
                     /tool="antismash"
                     /translation="ERVLHGIWCNVLGVELEDIGSDDNFFQIGGDSVNAMRVAAMARKA
                     SLNISVADIFAHPKLSSLSRLAS"
     CDS_motif       17673..17768
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HK57_00503_0024"
                     /evalue="1.40E-04"
                     /label="C2_LCL_024-062"
                     /locus_tag="HK57_00503"
                     /protein_end="3546"
                     /protein_start="3514"
                     /score="14.3"
                     /tool="antismash"
                     /translation="FAFAIEGSVDVEKLHKACAAVYQSFSLLRTLF"
     aSDomain        17673..18434
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HK57_00503_Condensation_DCL.3"
                     /domain_subtypes="Condensation_DCL"
                     /evalue="9.60E-34"
                     /label="HK57_00503_Condensation_DCL.3"
                     /locus_tag="HK57_00503"
                     /protein_end="3768"
                     /protein_start="3514"
                     /score="108.7"
                     /tool="antismash"
                     /translation="FAFAIEGSVDVEKLHKACAAVYQSFSLLRTLFLKHQDQTVQVILD
                     DVPVPFHHFVTDQPPARLLEVIRDADRENMPLYGQLPFAFILISHRDSLNHSLVCRAAH
                     PQWDGLSVGQLFKSISDAYLGIDLIPTTPLSTLVHYRLRQQTVDPSLRFWRNYLRGATI
                     TRLTQLPPHKDLSQGTTIWENTNMRPSPLAPKGITMASVVKAAWALVLSQESKTNDIVF
                     GQTVNGRNAPLPDIDMILGCCLNFAPVRIRLD"
     CDS_motif       17991..18041
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HK57_00503_0025"
                     /evalue="1.00E+00"
                     /label="C3_LCL_132-143"
                     /locus_tag="HK57_00503"
                     /protein_end="3637"
                     /protein_start="3620"
                     /score="2.4"
                     /tool="antismash"
                     /translation="WDGLSVGQLFKSISDAY"
     CDS_motif       18327..18422
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HK57_00503_0026"
                     /evalue="8.10E-10"
                     /label="C5_DCL_263-294"
                     /locus_tag="HK57_00503"
                     /protein_end="3764"
                     /protein_start="3732"
                     /score="31.2"
                     /tool="antismash"
                     /translation="DIVFGQTVNGRNAPLPDIDMILGCCLNFAPVR"
     gene            20976..22850
                     /locus_tag="HK57_00504"
     mRNA            join(20976..21281,21347..21509,21936..22153,22209..22850)
                     /locus_tag="HK57_00504"
                     /note="AUSM36_004"
                     /product="efflux pump antibiotic resistance protein"
     CDS             join(20976..21281,21347..21509,21936..22153,22209..22850)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 160.5; E-value:
                     7.8e-49)"
                     /gene_kind="transport"
                     /locus_tag="HK57_00504"
                     /note="AUSM36_004"
                     /product="efflux pump antibiotic resistance protein"
                     /protein_id="KIA75689.1"
                     /transl_table=11
                     /translation="MLGRIVDRLSRNSLGTLSRYDAKQLSSTEFTQDARLDHESPEQLG
                     VSQDMNLASLTDNKDESTYTTPDQSDTEPQNQPEYPVSWKLVLIVIGLGLGVLCMSLDN
                     TILATAIPRITDDFSSLEDMGWYASAYMLAQCSITLVFGKLYTLYPIKWVYLTLQWGGT
                     KYTWDDGRIIALIVVSGVLVLVFCAVERWQQDRATIPPLLIKDRNVWASVLFAFCITGS
                     FIVFTYYLPIWFQSVKGASATKSGIMNIPLVLSFSITSIVSGWAVTKVGYYMPLMYAST
                     VVASIGAGLLSRFQVDSRPPTWIGYQAIFGIGVGLGFGLPVTVVQAVLPGDRISSATAL
                     IAFTQSISGALFIFVGQSVFQTRLTLGLLRENLDARMALESGATRIRETIPPDMVPVAL
                     QAYNFAITGAFYVGLALAAASLVGAVPQRWLSVKGKKIEPGVA"
ORIGIN
        1 attgctgtct tcctgttgcc ctgacccgct gctcggaaac tagattaacg tgttgtaaaa
       61 cgagattgca cgcagaaaat gtcaggaacc gcacttataa gggcacgaaa gaaagctccg
      121 tgaaccgtgc tctgttggct atagagcgag aaatccaaag tatatgagcc aaagtacttg
      181 ctgatctact gctcatgggc tgggtggaaa gctaattgca gtggatgcta atttcatccg
      241 agttgttgga gacttaataa gtgccacgaa gcttactgcc atggcccaac aacagatatc
      301 cgctgcggac atcattgctc atccaaggct ggcttctctg gctgccgcgt cgagatgcaa
      361 taatgctttg attcacgctt cgatcttacg ccatttgctc ttcgcccgcc atggatccag
      421 gtacttctcc ctatgttgtt gggggctcga aacatgcttc acccgacgcc tacaatcatt
      481 gctatcttgc ctttgttgaa ggaccaaagc atcattctca agggaggggc cttacaccct
      541 ttctacctat cgttgaagga aaaatatatg tttagcgtat atgctatgct tgtgagactg
      601 cggatgacac gcattcagtt acaaggaatt gcaggtcctt gctataagtt tccaggtcac
      661 caacgagtgt ggaatgtgcg ccatactcgg ttccgcagct actgatgtca cacaaaaatt
      721 actggaaaaa ttctccaaga caactatcat ggttaaatga ggcatatggc caatttcaga
      781 gactataggc cccgaggggt ccgccgcaag ggattgccga tccattccgc tcgagtaaca
      841 cacaccgttg ctgttgtgct ctccgtatat attctgccta tagtcatcgg acgattgtat
      901 tccatctatc agcctatttg attttgatct caggcaacgc gttctctgcc gacatatccc
      961 aatttcacaa gtaccgtgaa tcatgctgga ccctcgaatt gccgccgccc ctcagtcatc
     1021 tggtatcaca gtgataatcg tcggtctggg gatcgcgggg ctgactacag ctatttcttg
     1081 ccatcttaga ggtcataccg taatcggatt tgacaaactc gaaaatctgg aaccttatgg
     1141 tgggctcggt gggccctttg ctgagatatc ggttagctga cacggtcttg taaactaggg
     1201 gatggtgtaa ccctggcccc gaatggcacc cgagttctcc gggaatttgg aaatggaact
     1261 gtcgcagaat ggatggagcg atgggctctt acctgcacca actgcaaggt ctttgacacg
     1321 agcggaaacc atattggcca acatccaatc ccagaaacag acagaggtct ggctctggta
     1381 ccacgaggaa agctcgtgca gactctctac gaagttgcac aagagctggg actcgatcta
     1441 cgcctcggcg tgaaaatcac tgaatattat gaggatcatg agcatgcgag tgttgttgtt
     1501 gatggaactc ggtttaaagg tgactgtatt ctttttgcgg atggagcaaa tagcaaacat
     1561 cggaagatag tttcaacgcg gaatgttgag cttcaccaat cgggattctc agtctaccgt
     1621 ggaaaggttg agggagaggt tgtgaagaag gaccccaagt gtcactggct gctaagtggg
     1681 gaaatggaga aggatgtcgc caaagctttt tcggggccca acatgtacct ggtactagca
     1741 acatgtggaa gtggaaaagc atgtttctgc attgcaatga gccaggtgag ttaaggactg
     1801 agtcattctc tcctcatata cacgcactta tacttttttc tgccagaaca ctaggccatt
     1861 agagaacgcg tggaccactc caattgataa agaagaggtg ttgaagcgtg tccgcggctg
     1921 gaagcttgaa caccaaatta ggccaatcat cgaacatatg tcaaaagatc aacttatcaa
     1981 cacccccttg gttcgtgcag gcgcgttgga ttcatgggtt tcaccaacag gccgtattgc
     2041 cttgatcggc gatgctgcgc atcccttctt ccctacatct gcccaaggcg catcgcaggc
     2101 aattgaagat ggcgcgactg tagctatcac tttgcaacta gcaggaaaac gcaatattaa
     2161 actgggtctg aacgctatga tggagcttcg gtgagtgctt tggttacgag aaaagatttt
     2221 tatcttgaca aaaaaacagc aagcatcgag cgacctatat ccaacacaac gcctggagag
     2281 taaatgatga gtggtttagg tctgatcaag aggaacgcac cggagacaag gcaagcccga
     2341 cgccaggtgt catggactgg atcatcgatc attgttgcca aacgtatgca tgggatgagt
     2401 ttgatcaggt ccgagagtgc attgaaacag gaatacctta tcacccaagc aatcttcccg
     2461 ccgaatgtag gtctattcaa gtccacgact aaattctttc attcttactg atgttgagcg
     2521 cgtaggctat gaaaaagcca cgaattttct tgaacaagga gggcatgggc ttcctttcta
     2581 gattgatgga cgaggcaaat cgggcagcaa aaaactaatg tcatgattac gcaggacaga
     2641 gtaggtcagt tgtcccgtct cacgtcgtct gccatttgct aggatattgg gaggatgtaa
     2701 tcgaacatct acgggaaaaa aaaatgctat cccaaattat tgaataaatt ctacatttct
     2761 atgactaggc gaactacttt ctatttggtg ttcgcagcga ggtgcacggc tttatttggc
     2821 cgttttcatt gcattatgca cgtggggttt atgttcatac aatgcctcat ggtgtagaga
     2881 tattggctct atacctgtgg tcgcgggttg cgctggttca gctggcaatt actgtccgcc
     2941 aatatgctag agtagtaagt tgctacccgt atctagcact acaaatgtcc accttagtat
     3001 ggtttattga atgtatttgt ccttctagcc ttaaagagca tcaaagtatt gtttgatatt
     3061 atctgtatcc ttatgttgcc tcgggctttt gctatgacca gactccaccc aagactcaag
     3121 ttatgtgaac ccaggaagca atatatagca ttttaagcct tcagagaaag gacaaatttc
     3181 ctttccccct tttcatccaa gctcaactca gctcaaaaca cctccccact ccaccgatca
     3241 cgcacaagcc taatctttac atccgccttc cgtctcgcga acatttgatc tgtccactcc
     3301 atgctctcag cattcgtgtc gacaagctcc aagtcgaacc tggaaaataa gatggcgagg
     3361 aaggagtaca tctcgtggta ggcaagacta gtgtagcgat agtcagcacg tctacccatg
     3421 accatacaat aaaccattaa ttatgttcgg taagaatgta gcttaccttg taccgataca
     3481 agatcgtgtt cccctgctaa acggtatata gtattgttcc aacgcttgac cttcttcacc
     3541 gagccatcgc tcgggtctga attgcttggg atcggagaaa cattgcggat tgtggtggat
     3601 tagatagatg gagtgcgaga ggatggtctg gaggagaaat cggggtgatt aggaccggac
     3661 agaaacaaaa agatggagtt gacttgagag acaggagtac tgacaccgcc agggaggaaa
     3721 tacccatcga cttcataccc gccggcaggg actgtccggg gaagcggagc aggagtgggc
     3781 gtgtacagac gcagagactc cttgattatg gccgtctaca gtggtcagca ttaatacact
     3841 gtatggcact accccggaag tagaattgat tattggactc acaagaaacg gcaactgctc
     3901 cacacgcacc aaatcatact gacctctaat ataggaagcc gccccgtcca actcctcgcg
     3961 gagccgcttg aagaccccgg ggtatgcgag aattgcgtag gttgcggtct ccattgtgta
     4021 ccccgtggta tcactaccac ccagaatgaa agcgcagccc tcgtcgacca atgcagatac
     4081 agaaggtatc ctgtgtcctt ttttgggatg tggttgaagg agtaagtcga caaccgtgtc
     4141 gtcgagagag atggcctttc ctgccttttt gtcggcgatg atctcttcga gttcatcagt
     4201 agctttctgc ttttagttag tatctcacat cggtatgaaa tggcatccag agtcattaac
     4261 acgcacccta cgaagctgga aatagcccgg cattaatttt ctcgagattc gttctgggat
     4321 gttcaccacg aaccatcgcc acaaggggat atatttgcct gttaaggacg atcagcgtgg
     4381 tcgagcgatc atcgaatccc agaactcaaa tccctacaaa catgaaaatg agccgtgaat
     4441 aacgccagat cttttagcag ctccggctcc tcctcagcgg aacttgtgag cccgaaggac
     4501 cgtccaaatg taaattcggt aattacatcg acctagttcc acagttacta tagtcagcaa
     4561 ttccatcctt ttttagaaag cagaaagatg aacagaacag ctaacggacc gttaaggaac
     4621 gagtgtgtcg agggaggatg atcgtacgcc cctgacgcgc ttttgtcacc atgacattac
     4681 agcagaggcg cacttggcct agaagcttgg gtgtgtacga tgcgataacc ttgggcgcaa
     4741 accgcgggcc caggattgag cgtctcacat ggtgttcctt tggatcgatg atcgttccta
     4801 ttgcctgcgc tagtccaacg gcagtagaga acatctgggt tttgagaaat ggagacgcga
     4861 ttttaaagac tctgcccgaa agtacgttag tgaacgagcc acttgcgcta acagcgaagt
     4921 cggccgtgga tagggctcat actccttgta tacttcaggg tcattcacgt ggacctcgtt
     4981 agggccggtg cgaatgaccg gtgattctgc aagccatttc tgtgttagca agaacaagac
     5041 aacttacgag cggggactgt taaaatcgca ctgtaaattt cgtgtagctt ttcaatgtgt
     5101 ttgatgtaat tcccactgcg aatcacatcg tgatagaatc cgtagcaatt actccaccct
     5161 gccaggtatg gaccggggat tttgctcaaa gggtgggaga tgagacgcga aaaggcctgg
     5221 tgcaccaacc ccgcgacgag gatgccgacc gccaggctgg tgaacataat ttggacgttg
     5281 ctgctagggt agtaggactc catggccacc atggtttgct tcataatccg gtgtattgga
     5341 cggcacaatc ggatacaacg cactatcaac ttgttataaa ggccgatcag ctcgtctagt
     5401 aaaatgccta tattgcgaac gtttcatgga gaaagtaaat actccccccc aatgcaaggg
     5461 ttgggtcgag tccgacaatg caaggtgtcg tgcagggtgg acgaagtcca ataactccaa
     5521 tacctccatg gtgcttaaaa actacacttc aactattctc gtcatctgca tattaagttt
     5581 accgcgcttg atgatttggc atgaaggggt ttgtccctta cctactgctt tacctgcaag
     5641 aatacgtgga attgcgggag tgtatgggtc caatgcactc actattctaa actatggtgt
     5701 accaagcagc aaggattggc gtaactacat tggagcgata tttctccata attagctctc
     5761 cttttagtgc atcctgggca gagttttatt tcattaccaa cgcatcaggg tggcacaaga
     5821 gtacatcacg cgcggcccat atcagagaag ctacgaccaa gaatgccgtg aatacatatt
     5881 ttaatgaact agggcgtggc cttgtcagcc gtggatattg aagtcaggta gttactctgt
     5941 ttttgcacac ctcctgcatg agatgattgc caaaagtctc accgtcacca ttccagcaat
     6001 gttctacttg ttttgaactc accacgctaa tctcacctat cgcgcgagga taaatacata
     6061 aacattatca cacagccctc atttgagaaa agtaagtata tagcgtaaag tttgttatat
     6121 tatataagct tttcaatggt attagaggtg tttaaaatag ccttgattta gtaattttta
     6181 acaggaagaa aggaacaatc attaggtggt actgagcatc aggagatcac ccactgttgt
     6241 agacttgaag tccgtgccac agagcattcc ttgcgggcaa ggttccggga tatccctggc
     6301 aatgttccac atatcccttg catccgtttt caagtttgct ctggattctc cgggacggcc
     6361 agtctagcat gttgcaacca gcttgaaaga aacttccggt acgttccggt atgtaccggg
     6421 ccgtggccat tgccgcggag ttggcggagg gggtggcgtg ttgattggcc ggaaaaaaaa
     6481 tactccgccc acttggcatt gggtggtagc taagacattc attctatatc gccgagcatg
     6541 gactgagttc agtgccgttc ggctgatcta gaaatgatag ctggcaagga cgcgtttgca
     6601 gcactgtgca aatcgtgtat ggcgggacta cccataaggg cagccataac aagttctaga
     6661 gcaaggcaaa gcggtctagc tggtattgag atcctctagc ggacccccgg ctgccaatga
     6721 acagggctta gaatccgaag gttgctcatg taaggcctcc agctcagaat gctaagtcat
     6781 tagaaagaat ctaggtggtt actcaacgtt ttccgctaac gtgaaaatgg caagtgcgta
     6841 tgcatagcca tcaataacat aggatggaca tcgaatgcat ggtgaatgga tatcaaatgg
     6901 gacgaaacga ggggtgatta aaacaaatct tgatagtgct tctgagaaat catacgcatc
     6961 tcctccatca ccctttgcat cccgaagcct cattttctta cctatcgccc actgtacgga
     7021 aatcaaatcc ggccgtctat ctgataacga ttgagcttga attaaacaat catggccatt
     7081 gaagacgccg ccaagcccga cgagccgacg tgggtgtgcc tgtttccacg gctcaccgga
     7141 gagccaccgg gtaaaggcac tcgagagacc actcactttg atccaatgac aaatagccta
     7201 ctcgacaaat gtagcaagca gtttcacgtt gcaccacacc tggtgctggc agccgtatgg
     7261 gccgctgttc ttcgccaata caccgagatg gataacccag gattcgtcat ggtccagccg
     7321 agtcgtgagg gtcacaataa ctataccgct gagggttaca gtacacaact tgaccatgat
     7381 gccattgtcc agaaatacat gagagatacg agctgggagc gcttttctct tgtgcaagga
     7441 acctatatgt acaacactgc gctggttatt ggggacgagc aggatttgcc caccgaggtt
     7501 agtcgtcgtc acctccatac ccttcatcca gtctctaatt gccgcggtgt gcacagtcag
     7561 tcgatatcag tattatgcta cagctcgaac agcagccacc cgccttgtca ctagcgtata
     7621 ccacacaggt tgtttcaact gtcttcgccg aggttgttgc cagcgccatc tctcagagca
     7681 tctatcatct tcaaagagag ccgaatgttt tgcttaaaga tctggacctt tcctctccgc
     7741 ttagcgcgga gatggttagg tcatggcagg ggtgtgcatc gatttccacc aagcacgatt
     7801 ttatgttcga ggtaattgcc cggcaggctg cacagaggcc aaacgcagtt gcggtagacg
     7861 cgtgggatgt tcggtggacc tatcaggagc tggaaaaagc ctcctcccag ctagcatttc
     7921 agctgcagac acggggggtg gggactggtg tgcaagtgct catgtgcttt gaaaagactg
     7981 gttatgcggt gcttgccatg cttgcggtca acaagactgg ggggtcgttt gtcccttgtg
     8041 atccttcata tcctgctgag cgtcgtcggc aaattttgcg acgcattcat gcgtctgtgg
     8101 ctcttacctc tcctgaatgt ggggaccttt tctcagacga gacgggatta gatgttgtga
     8161 ccgtccctgg ctgtgccatg gcgccctcaa tacccaaaac tgtgccgaag agctgtctga
     8221 gtcctacttc gccagcctac attctgtata catccggaag cacaggggag cccaaagggt
     8281 gtgaaatcac acatgccgcg ttcgcgagta ttgcagagca cgcagaggca cttcaattaa
     8341 gccccaccac tcgttcgctg caatttgcct ccttctcctt cggaatggca atcattgaga
     8401 tcttctgcac gcttgcagct ggaggggtag tttgcatgtt gtctgctgat cagcggtcaa
     8461 acagccttgc ccataccatg acggagatga aggtgaactg ggcatttatg actccgaccg
     8521 tcttaagctc tcttcagccg caggatttac cttaccttca tgatttattt attgccggag
     8581 aagcaatgag cgagggccat gtccggacat ggggatcctc agtgcatgtc caccaagcat
     8641 atggcttgac agaatggtct gggatcttcg caatatccga ccgcatgaca gtgtcgcatg
     8701 agcgggccac tattggcaga ccagtcaatg gccttggatg gctggtcgat ccgcttaatc
     8761 aagatcgact tgtccccgtc ggcgctcctg gtgagctggt catcagtgga ccgtcattgg
     8821 caagtggtta cttcgaggat ccccgacgct ccaaagcttc cttcatctcc ccagcctggc
     8881 gacgaacatc tacggatgta gaagaccggc tgtacagaac gggagatatt atgcgctaca
     8941 gcatggatgg aactttgcaa tatatccgga gaaaggacag ccaagtcaag atccgaggct
     9001 tacgagtcga attgggtgaa gtggaatcta acctgctgcc gctcattcca gaggcaaagc
     9061 gcgtgattgc aactgtgtgg cgcccgctag aggacagcca tcagcaatta cttgtcgcgt
     9121 tcgttctcct acgggtgtct gatgctacca ccattccgct agtgcgtggg gcacacgcct
     9181 gcgaattaca gattctggat ttgacgcccg ctcaatcgca gggcctgcgc gatgctcacc
     9241 acacattgcg aagccaactg ccgggctata tgataccgca gcacctgatc cctgtggctg
     9301 cggtaccaac aacttacact ggaaaggtgg accgtcggaa actgggggct cttctgaata
     9361 aaatctcgcc cagctacctg tcgcagctcg ccggacagcg atcagagtat caacaacccg
     9421 caaacgagcg cgaacaattg attcatgata tgacgtgcag catccttgga ttaaaatcag
     9481 caagcatgca ggacaatttc tttaatatct ctggggactc tgtggcggcg atgaaaatgg
     9541 tcaggctggc ttcttccaac aaggtgtctt taaccgttgc aaaaatcttc aagtaccctg
     9601 tactcaaaga catggcggcg cagattggtc agagaaatga cgagcccgct gcaaatcctg
     9661 ttggaaggtt tgggctgttg ctcaatgcta ctccgaccga tgtaatgcgt gaagtggctg
     9721 agcaaacaca tctcgatgtg gcccaggtgc tcaatgccta cccctgcact ccgctccaag
     9781 aaggtctctg cgcgctctct gtgagagatc agcgagctta caaagcacgc atcgtatgtc
     9841 aagtggagcc gagtgtcgac atcagcgctg ttcgacaggc ctgggaacga atattcgaga
     9901 tgaacgacat ccttcgcacc cgcctggttg catcctcgtc gcatggcacg atccaagctg
     9961 ttatgcaaga gaattttcag tgggattacg cggagaacct ggacgaatat agcgcccgag
    10021 tcagcaagga gcccatggga atcgggcaca ggctggttag ggcatgcctc ctcgccgacc
    10081 cacggaccaa gacagggcca gccactctcg ttttgacgct gcaccatgcc atttgcgacc
    10141 gatggtctgt cgggctactc ctggagcaat tggaaagaca gcttgggctc actacgaagc
    10201 ctgtcttaga acaccacgag ttcctcccct ttattgaaca cttggccgac cttgcttcca
    10261 aacatcagga gtactggaat agccagttcc atggcataga agcgcagatt tttccagagc
    10321 ttccctctcc gtattatgat cctgtagtaa atcaaaccct cactactcag gtcgtgttgc
    10381 cagaacgcaa cttgcgagac aagacggtag cgagccatgt acgtctggca ttagcgcttg
    10441 ccattgcaca tcacacatgc tctgatgata ttatatttgg cgcgactgtc agtgggaggg
    10501 ctgcgctaat gagtggtatt gagcgcatgt ccggcccaac gattgcgacc attcccctcc
    10561 gaatagcact caacagagag aacacggtcg ctcagtcact atcggccatt caagcgcagt
    10621 caattgagac catcccgttt gaacaagctg gtctgcagaa tatccggaaa tatagttccg
    10681 agtcggacta cgcctgcaaa tttcaaacac acttgaccat ccaacctgcc ttgtgtgagt
    10741 cctttgcgct cctcaatgtg attgaacaag gaccagcaac ccctggagga ttcgcgtcct
    10801 atgctctctg tctcgaatgc tacttggagg gagatgagaa gagaatgaag gttatggctg
    10861 cctttgactc aaatgtcatc tcatcgccgc gggtggcacg gttcattaac cacctggaat
    10921 tcgtcctcca cgagattatg aagaacccag atcaactgct atcatcagtt tcccatatta
    10981 atccatcaga tatgtcccaa ctatgggagt ggaacacaac ccttgctagc aagcccaagc
    11041 tgcaggactc cgttcacaag gtcgtccagg aacgtgccca tgagacacca gccgcgacgg
    11101 caatatgtgc acatgacaga atattcactt accgagacct agagacacgc gctacccatc
    11161 tggcaggaga gttgttgcgg cggggagtgc ggaggcgcac gctagtcccg ttgttgtttg
    11221 agaagagcgc ttgggccatt gtctccatgc tggccgtcat caaagcagga gcaggaattg
    11281 tcgccttgga tccttcctat ccgctcgggc gcagtcaggc aatctgtgaa caagtcggta
    11341 gttcttttgc cttgtgctcc aagggattgg caattaccac gcagaaatta ggctgccaac
    11401 ccgtggttgt ctcagaggaa gctccgatat ggggtcatac gattgaagca gaagagcttc
    11461 ccccggttgg gccaagtgat atcttgtact tgatctttac ttccgggtcc accggcgccc
    11521 ccaagggagt cattgtcgaa catggttgtt ttgcatcgtc caccgcggcc tatagccccg
    11581 agatcaaact gcgcagcgac tcgcggatgt tgcagttctg ctcctttgca tttgactgct
    11641 gctttgttga aatcttcggc acattgatga caggaggttg tctctgcgtg ccctccgacc
    11701 aggatcgcac taataacatc cataatgcca tcagagagct gcagatttcc cacgctgttc
    11761 ttacaccttc cgtcgcccgc cttgttcagt tagagccaat accctccttg aaggttctca
    11821 tgttagctgg cgagcctgtg tcagcatcgg atgtcgagta ttggtcgtct cgtgtctacc
    11881 ttgtgaatgg atatggtcct tcagaatgtg ctcccatctc tgctacgcag cacaacgatg
    11941 gtagtaatgg tattcatgcg cgggatattg gccggacaac gggctgtata ggctgggtgt
    12001 gtgatcctcg ggaccacgga atccttgtcc ccattggagc cactggcgaa ttgattctcg
    12061 aggggccaaa cgtgggaccg ggttacttta agaatccctc ggagacggaa tctgcattta
    12121 tcaactcccc accctggctt cgtgctttgc gcaagaacac cagtcgcgtc tacaagacga
    12181 aggacttggt tcgttacact gaggatggcc gcctgcaata tgttgggagg atcgggcatc
    12241 aggtcaagat acgtggccag aggttggatc catcccatgt cgagagccag ctgctgcaac
    12301 actttggcgg tgccatcaag gtagcggcag ttgtggccac gcctggaaat gcgaacaata
    12361 gcagcagtcg tgcggtgctg gtggggttta ttttaacaga tgaggatcaa acgcaagagt
    12421 ccagagttgg tgatgctgtt tgtgcacctg ccagcgactc gttctcgcgc cgcgcgacga
    12481 gtgcccgctt aaagctgcag aaaagcttgc cagagttcat ggtaccgtca ttgctgatcc
    12541 cattacgctt catgccgcaa acaccttccg ggaagcttga tcggctccgg ctaaggcagg
    12601 aaatcaccag caggacatgg aaagagttga tgcagcacga aacagccagc ggtggggagt
    12661 ctgtggaaat gccgtcaacc gatgcggaac gggaactgca gatgatttgg agtcgtgtgc
    12721 tcagcatacc ccctgagaat gtcggggtta accaaccctt cttgacttgc ggtggagatt
    12781 ccatcacggc catgctggtg gttactcagg ctcgtcgtgg tcggttgggg ctaaacatca
    12841 ccgtggacga tatcttcaac ctccacacta tttcacgtct agcggaccat gcggcgacaa
    12901 catccgtccc ctatcagctg agtgctaacg gggtggggat tgcagttgat gtgcctttcc
    12961 ctctatcccc catccagcac ctcttcttta gcaagaatcc gcaggggagt aaccgcttta
    13021 gccacaacat tttgcttcac ctggagcaac cggtcacact tgaactactg agacatgcgg
    13081 ggcagaactt ggcagaaaag cacccgatgc tccgtgcacg attctcgcgc gatgccagtg
    13141 gacagtggca tcagttcgtc cacggggacg tgcaggggtc ggtggcctgc aggatccatc
    13201 gtctacgtac caaatccagt gtgcgacgta tactggcgca gagtcgagaa ggcctcgata
    13261 ttcttgcagg cccagtgttt tccctggacc tcattcaaat cgatggtcgc caatctatct
    13321 tcgccctggc gcatcatctc gtcatcgaca tggtatcctg gcctgtgctt ctagcggacc
    13381 tggaggtgtc cttgcgtggc ggctctgtcc agagcctacc ttcgacttca taccagacct
    13441 ggtgccgtat tctcgccgag tccactagca gtctatcact accacccgtt gaatctattg
    13501 atagcaaaga aatcacaagt ttttggggcg tctccgacaa cctcaatgtc atcggattaa
    13561 cgagcgaaaa ggtgcttaat atcgacggta ccattactaa tgcagttctg ggcaaagcaa
    13621 atgatgcctt tggcacccaa cctgttgagt tgatccatgc cgcaatttta cacgccttta
    13681 tcactacatt tccgtctcgc aaggctccgg ccatatattc ggaaggccat ggacgagagc
    13741 cgggcgagga cacgacggta gacatcacca gcaccgtcgg ctggtttaca agtatcgcgc
    13801 cagtctgtgt gcagcccaaa ggccctgctt gcgacctatc tatggttgtc cggcaagtta
    13861 aagatgcccg tcgtcaatct ccaaggaacg gcctagaagc ctttacagcg aactactaca
    13921 actcgaacaa tatgcaagtc gaccccgccc acacaatgga gatcaccttc aactatggtg
    13981 gaagatatca ccaacaactc gagcaaacat gtgatctctt ctcaatagag ccacttcaaa
    14041 atctaggcat ttttgacgct gcgcacagtg tggcccggtg gtcctttgtg gatatcaacg
    14101 cctttgtcca cgatgaggag ctgaacctgg ctttcacttt tcccaaaggc tgcagccagg
    14161 ctcaggtgct tggcccatgg atgaacaata tccgtaatgc ccttcggcgc atggcgtcgg
    14221 agtttgtcga atatccccgg tcattcacta tgaccgattt ctcctgtctc aacttgagct
    14281 acgaggaact tgatgccctt cggtcccgtc tgaccgtcgc tggcattcat cccgagaatg
    14341 tggaggatat ttatccatgt gcccctatcc agcgggggat actgctgagc cgcgccagaa
    14401 accccgattt atatcatatt gcaatgacat gggttgtcaa gcccccgtac agttcggctc
    14461 ccccatcggc ggaacgtgcc agatctgcta taacgcaggt tattgcacgt catgcctttt
    14521 tgcggactta ctttactgtg actgaatctg aagattccat gtacgaccag gtcgtcgtgc
    14581 gggaaatgcg accggagatt ccagtgacat acagcgagaa aagcgcacag caagctttgt
    14641 cgaaggctga tgaaacattc cggcccagca cggaatgccc gtaccggttt agtattctag
    14701 tgtctggtga caaaagggtc tacatccgcc ttgacatcac gcatgccctt gtcgacgcgc
    14761 atactttgga aatcctggag cgcgagcttt gccttgcata tgacggcaag ctgggcgtgg
    14821 acaaggcccc atgctactcc agttacattt cattcctccg cagccaggat agagaagctg
    14881 accgagggtt ctggcaacaa tacctggctg gaagccagtc gtgtctattc cctgccctaa
    14941 caggccactg tgccaaggag cccgactccc accgcgatct ggtttttgaa atcggtaatg
    15001 ttgatcggtt gcgaacgtac tgcaagtcgc gtagcgtgac agtcgctaat gtattttcgc
    15061 ttgcgtgggc acttatcctg cgggcctatg ttggcgagac tgacgtgtgc tttggcttcc
    15121 ttgtttcagg tcgcgaactg ccctttgccg gagcttccga cgtcggagga cctctcatta
    15181 atatgctgac cactcgcctg cgactggcgg gagatgcccg attgtgtgaa ctccttcaag
    15241 gcgtgcaggc cgactttctt gcctgccgcc gtcaccagac gtatccgatt ggtgatataa
    15301 tccatgatca aggaagctca gaatctttca aagtgaacac tgcgctgtca gtgcaacggg
    15361 ttctggaaga tgaaacgccc tcgacaggaa ctgcgatgag cctggtgcac cgccaggacc
    15421 cctcagagta cgccattgcg atgaacgttg aaatcgaaaa ggatcgcatc gtgtgccatt
    15481 ttcggtactg gctttccaat ttgtccgacg cacaggcttc gttggtcgct tcgtcctttg
    15541 accaggcagt gtcccagatt gtttccaacg atcaggcgac tccctctgaa gtcaatctcc
    15601 tgtcgccaca ccatcgggac ctgatctgga attggaacgg ttccctcgcg tcacccggtc
    15661 cagcctgtgt gcatgagata atacgccaac gcgtggtcga gagccctagt tccccagccg
    15721 tggtaaccac agagggtgct ctctcctatg gcacactcga aactctttcg gaccggttag
    15781 cgcattatct agtgcagata ggcgtcgtat ccgaaatgat tgtgccttgc tgcttcgata
    15841 aagggacatg gacagtggtg gccgtattgg ctgttctcaa ggctggggga gcctttgcgc
    15901 tgatggacac catgcagccc gaccaccgtc tagaaagcat ctgcgcggat gccaacagcc
    15961 ccatcattct ggcatctgta aggcaggcgc cccgatgcgc aaagtttggg aagaaggtgg
    16021 tcgccattgg aggtaatgat gatgaccgat ggaacagacc cctgctgcgg agtaaacatt
    16081 ttgttcacca gcagcagccc aactcaaaga atgccatgtt tgtggtgtat acatcgggtt
    16141 ctaccggaaa gccaaaggga gtgataattg agcatggctc gtttcatgcg atgatccaag
    16201 cacaatcacc gctctggtac atgacagcca ctgcccgcct catgcaattt gcctcgtatg
    16261 cctttgatgc cagcgtgctc gagatgcttc taccgctcat gctcggcgcc actacttgta
    16321 ttctaaccga ggtggagaga cgagaccatc tgcgcgagtc catcgtgcag cttggtgtca
    16381 ctcacgcctt cctgacgcca tctgtcgctc gccttctttc tccagccatg gttccaaatc
    16441 tggcggtgct gatttgcgtt ggagagccga tgacgcagct tgatcttgat gagtgggcca
    16501 atgatgtccg cttgatcaat gcatacggac cagcagagtg tactattggt gcaattactc
    16561 agcccatagt cacaactaca tcccgaccag gggatattgg gcgcccggcg gggtgtgcag
    16621 catgggtggt tgatctggag aatagccagt gccttgttcc gattggtgcc gttggagaac
    16681 tcattattga agggcctacg gttgggcggg ggtatctgaa taaccctcaa gccacggctg
    16741 ctgcattcct gtcccggcct tcgtggcttc gcgacctgcg cggcgacact aggatataca
    16801 agaccgggga tcttgtccgg tatggcccgg atggtcagct ttatatcagc ggacgcaagg
    16861 acacgcaggt gaagattcgc ggtcagcgca tcgagctcgg cgaaattgag tatcaagtgc
    16921 attgcgcttt caaggatgtg caggatgtca ttgttgagat ggtcttggtg ggtcccgaag
    16981 ataacaagac tccaactctc tttgctctta tttccgggag tcatattggt cctatgggtg
    17041 acgacccttt tcttgtcccc gatgagactt tcaaattaca ggccagctcg gcaagtgcga
    17101 gcctgtttca gaaattgcca gcctacatgg taccgtctta tttcatccct ctgtcagcga
    17161 tcccggtagg accatcgggc aaggctgacc gcaagcaatt gcgacgcttt ttggccaacc
    17221 ttcagggaga gcagctgaag atgtaccgtc cgacaggcgg aagtcagcgc acggtgacat
    17281 ctgtacagga gagggttctt catgggatat ggtgcaatgt gctgggcgtg gagctggagg
    17341 atatcggatc tgatgataat ttcttccaga ttggcggaga ctcggtgaat gcaatgaggg
    17401 ttgctgccat ggccaggaag gcgagtctga acatttccgt ggcagatatc tttgcgcacc
    17461 ctaagctgtc atctctctcc cggctagcca gtaccatcgc cacagaacac tttgagcctg
    17521 tcccattctc tctcaaccca gtaagcgaaa tggatggctt caacctcttc cttcagacac
    17581 gtcgcggcat cccagcctgt gcgaagattg ttgatattct gcctacctcc gctgcgcaag
    17641 cattcttcct tgagcgtcct accctccacc atttcgcctt tgctattgaa ggctcagtgg
    17701 atgtagaaaa gcttcacaag gcctgtgctg ctgtgtatca aagcttctcg ctcctgcgaa
    17761 cactcttcct caaacatcag gatcagaccg tgcaggtgat ccttgatgac gtgccggtcc
    17821 cgttccatca tttcgtgacg gaccaaccgc ccgctcggct cttggaagtg atacgtgatg
    17881 cagacagaga aaacatgcca ctgtacggcc aactaccctt tgcattcatt ttgatatccc
    17941 accgagacag cctgaatcac tccctggttt gccgagcagc ccacccccaa tgggacggtc
    18001 tctccgtggg acaactgttc aagagtatca gcgacgccta cttgggtata gacctgatcc
    18061 caacaacccc attgtcaacg ttagtacact atcgcctgcg ccagcagaca gtggacccat
    18121 ctctacgttt ctggagaaac tatctacgtg gggcaacaat cacccggcta acgcaacttc
    18181 ctcctcataa agacctctcc cagggcacca caatctggga aaacaccaat atgcgaccat
    18241 ctcccttggc accaaaaggg atcacaatgg ccagcgtagt aaaagccgca tgggccttag
    18301 tcctatctca ggaatccaaa acaaacgaca tcgtcttcgg ccaaacagtc aacggtcgca
    18361 acgccccact gccagacatt gacatgatcc tcggctgctg tctcaatttt gcccctgtgc
    18421 gcatccgtct ggatcaaata ggctcaatct ccgaccttct ctctctcgta caaaaccagt
    18481 accagcagac agtgcagcac gacgaaatcg agctccccac tatcatcgag cgctgtaccc
    18541 cctgggcaag agagacggat ctccactcca tcgtccagca tcaaaatatt ccccttacgc
    18601 acgacttgtc cctaggtcgg ggtctcaaga cgcagttctc gttgaatggt tacttccggc
    18661 ccggcaagga ggtcttcatc tttactgagc caatgggtga catactgagt gtgcagctct
    18721 gtgtcaaccc gaatgtgatt gggcttgagc gagcgagtgg actgcatcgc aggttggtga
    18781 aactcattgg tgatttgtgt tacttggatg gtggtgaggc ggttgaaaag cttttaaaag
    18841 tggtataggt atggttggtt ggttaggtta ttactgtgat tattctaagc tgttgcccta
    18901 tgttatttct gaatacaaac cagtttatgt gggttgcaat agacaggcta agatttcacc
    18961 ctatggcatt ataagtagtt gtagcccaag acatactagc acacgactgt gctgtggtgt
    19021 ctctatgtac acgattattc aacccttgat gtatttagca acttgaccct gaatagatat
    19081 cctctggagc agcggtacac accagagaaa tctagggacc atcttggctt gtcctagcat
    19141 atattagctt agtttagctt cgcttcgtat ttcccagcct ttggcgccag gtgacaaagc
    19201 tacatctcct ggcttcaacg ttgagatgtg atatgtgtag taaagtgtac ggctgatccg
    19261 cctgatcaga gtgccatcga taagacagac aaaagtttta cgttggtatt attcttactc
    19321 ccgcgcttca ctatgttgac gttatctgct cttaattctc taaacctgtg aactctgtat
    19381 ccaggtgttg ctgctgtctc gttctgtgtg gttctggctg ccaacccttc attcctcttc
    19441 cccgtgaatc attacttcat gcgttgcctg cccgcggggc acttttggcc cttggccctg
    19501 cttcaggcgc caggctccag cgtctccagc attgtgtccg aggttcaaac atcgttgctc
    19561 caggcgcttc atgagggtcg aagactaata ccttgcatgg ggtgacctcg agcgttctat
    19621 caccatgtag aatgacgaaa ggaccaagga caataaacaa acggcaatgt ttgcaaccgg
    19681 ggcaatagaa tcattctagt ttcatctcct gttgtgcgcg agccatctgt agcggcttgt
    19741 acgcatcaaa cgagcggagt ttttacccta ggctcaggca gaccgtgctc gtcaagggat
    19801 aatatttgtc cctgctatcc cacagcataa tatccccacg ttaggctgca tattctcttc
    19861 ggaaatcaat tgcaagtgct gggatcaccg ggctgtggta ttttggcctc tctcgatcta
    19921 gtcttggcct tttcgctcaa attcgacact taatcccaga aagtgaaata tcctgatgaa
    19981 tttggattct atattgactg acgatgaaag ctgtgactcg actactcggt gctagaagtg
    20041 aatctggatg tgaccttttt ggccgataga taagcacatg ttccgccctg gactgtgtcc
    20101 cgtctcacga gatcctagtc taagaggaag tctgtgcact aggctaatac cgttgtgatg
    20161 gggaacacat cacagaaacc accgctcata tccttgtgtc acagatacgg tccaatagaa
    20221 tgacgttctc tatgattact ctgttcggca tgatgatgta tgccgttgcg ctgcttaatc
    20281 tccagctcat gcagttgaga gcaagacgga ttccccttgc ctcacattga gattcctccc
    20341 ttggctcccc gctcgctctg gaatctgatg gagctgctca ggagaaaggc gggttcgtga
    20401 tttaggcacg acacaatatc agattgtgcc aaattgactc catgtgtata tgggattggg
    20461 acatgaagaa tattcgagat gtttattctc tccccgctga ggatctattg cttcttcgtg
    20521 ttggtcatat cggcagagct tgatctataa ctgaccctat ctagggatga tttctaaatc
    20581 tagggataac ccctttttct ctttttcccc tccctccttt tttttttctt ttttgggcaa
    20641 aagagaaaag aatacacttt cctggtcgat gactgcaata aaagagtcat tatttatgtt
    20701 tgtcagaaac aagtaatgca cgatgttgcc cagctgaatg ttgtacagca tcataccaca
    20761 ttttcttttt gattacggca tagatcagcg acgattctaa cacctgatgg aataggcctt
    20821 cccagggatg gtactctata taatgggtaa tactaaattt gagctatcca atatcattcc
    20881 atattctttt tttggcgttc gtcttgctct cctatcgcca gctcctgact agtatttatg
    20941 tctagtgggt aatttttatc tactaagcaa tcaacatgct gggcaggatc gtggaccgct
    21001 tgtcccgaaa ctcactgggt acactatcaa gatatgacgc caagcaattg agcagtactg
    21061 aatttacaca agacgctcgc ctcgaccacg agagcccaga gcaacttggt gtttcgcaag
    21121 atatgaacct ggcgtcgctc acagacaata aggacgaatc cacgtataca acgcctgacc
    21181 aaagtgacac cgagccgcag aatcagccag agtatccggt atcttggaag cttgttctca
    21241 ttgtcatcgg gctaggtcta ggagtgctct gcatgtccct ggtaaatcga gactttcatc
    21301 cgcaccaaac tacctgtgaa gctgatctct tgccgaaatt ctgtaggaca acactatcct
    21361 ggccactgca attccgagga tcactgacga cttcagctcc ttggaagata tggggtggta
    21421 tgcaagtgca tacatgctcg cacaatgcag cataaccctt gtttttggga agctgtatac
    21481 actctaccct attaaatggg tctatctgag tgggcttacc ctatttgaag tgggctcctt
    21541 aatctgcggt gtcgcgccca gctcgttgac actgattatt ggacgtgccg ttgcgggact
    21601 gggaggcgct gggcttttat tgggctctta tataatcgtg tccaccatca ctccgccaaa
    21661 aaaaagaccg atatataccg cactcttgtc aagcatattt ggcttggctg gagtcatagg
    21721 tccactgcta ggaggcgcgt tcactgacta caccagctgg agatggtgct tctatatcaa
    21781 tcttcccttg gggggagtga ctgccttttt tatacttttc tttctgcgac accaaaattc
    21841 ggcaccatca tcaaccagca tattgaatca attcctagaa ctggatatac ctgggattgt
    21901 tgccttcctc ccagctataa tctgcttatt actagctctc caatggggag gcaccaagta
    21961 tacatgggac gacggacgca ttattgccct cattgttgtg tctggggtgt tggtcttggt
    22021 attttgcgca gtggagcgct ggcaacagga tagggccacg atacctccgc tcttaatcaa
    22081 agatcgaaat gtctgggcct cggttttatt cgccttttgc ataaccggct ctttcattgt
    22141 ttttacctac tatgtgagtg ctcggctacc cccagtatca aaaccaagct aatcagctat
    22201 acacacagct acctatatgg tttcagagtg tcaagggcgc ttccgcaaca aagtctggta
    22261 taatgaatat cccgctggtc ttgtcgtttt ccattacatc aatagtctcc ggttgggctg
    22321 ttaccaaagt gggatattat atgccactta tgtatgccag cactgtagta gcctcaattg
    22381 gggctgggct actctcgaga ttccaggttg actctaggcc tccgacctgg ataggctatc
    22441 aagccatttt tggaattgga gttgggctag gctttgggct gccggttact gtagtccaag
    22501 ctgtacttcc tggcgacagg atctccagtg caacggcact gatcgcattc acgcagagta
    22561 tttcgggggc attgtttatc tttgttggac agagcgtctt tcagacccga ctaaccctcg
    22621 gactactaag ggagaatctc gacgccagga tggctctaga gtctggagca acaaggatcc
    22681 gtgaaacaat accgccggat atggtgcctg ttgcattgca ggcatataac tttgctatca
    22741 caggtgcatt ttatgttgga cttgctcttg cagctgcgtc ccttgtcggg gccgtgcctc
    22801 aaaggtggtt gtctgtcaag ggaaagaaga tcgagccagg agtcgcctag ccgcccagta
    22861 tttggcctgt catcaatgag tcgacgttgg ctttctcacc ccagtgactt gatttttctt
    22921 cggttgcgcg gtccatgaca aagttcaata ccaccatttt caaccaagta atgcataccc
    22981 gtaatgttat gttaccattt tgagtcgcat agatactatg ttgcaggttt aatctgacca
    23041 gaagatttcg ccagcgaagc gccgcaatta agatcgtaga tagcatcgtt ctggccgggg
    23101 atagtgttat cgtgttgagc catcctgctg agccttggat ctggatgttt ggcgagtagt
    23161 ttggtacaca ggcgaagcgc acatctcaag tgagtctctg aattaaactt tgtagattcg
    23221 ttgaacttca tgtctgtggc ggacctcatg tggaggcatt aaattaagag gtagtgatca
    23281 tgctgcgtcg attttcttat acacgaattc agcagttggt taaggagtca acttgactcg
    23341 cttgctccca gttcatgacc atcagcaggg ggtcagaccc gccggaatcc gatgagggcg
    23401 gtcgctgtct gaccgcctaa gtgtattgta tagcctgctg atgctgctga tgcttgccag
    23461 gatgcatggc cagacggcca ctcttgtcaa cgctgcaacc aagccggatc tgataccagt
    23521 aatgttgaat aaaactatca aataagagca aagacaagga cacctctagt aataaaactt
    23581 tcccttcact caaaaatcag gttttcatcc tgtaatggtt gaccagaggc ttaattcaat
    23641 taaatacacg ctcaagcaac tcctccatga atgcttctag agaagcaaac gacttgccca
    23701 tagcttttaa ttcattaaga tcagcctctg tttcgcggta aagagtagtg attattgctg
    23761 ttagggcctt gttggtttgc tgaggtgttt tagagcttct tttca
//
