BGC0002244 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002244 (Neopestalotiopsis clavispora)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	45,207	3'-methoxy-1,2-dehydropenicillide/pestalotiollide B/pestalotiollide C/1,2-dehydropenicillide/3-methoxy-1,2-dehydropenicillide/1,2-epoxy-3,4-didehydropenicillide	PKS	100%

BGC0002244 - Region 1 - T1PKS

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Location: 1 - 45,207 nt. (total: 45,207 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 45,208
Label		BGC0002244

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002244	0.72	Polyketide	3'-methoxy-1,2-dehydropenicillide, pestalotiollide B, pestalotiollide C, 1,2-dehydropenicillide, 3-methoxy-1,2-dehydropenicillide, 1,2-epoxy-3,4-didehydropenicillide	Neopestalotiopsis clavispora
BGC0000013	0.37	Polyketide	alternariol	Aspergillus nidulans FGSC A4
BGC0002236	0.35	Polyketide	8-methyldiaporthin	Aspergillus oryzae RIB40
BGC0002253	0.35	Polyketide	waikikiamide A, waikikiamide B, waikikiamide C, (+)-semivioxanthin, semivioxanthin	Aspergillus sp. FM242
BGC0002596	0.33	Polyketide	lecanoric acid, orsellinic acid	Claviceps purpurea 20.1
BGC0001542	0.31	Polyketide	cercosporin	Cercospora zeina
BGC0000161	0.31	Polyketide	isoterrein	Aspergillus terreus NIH2624
BGC0001541	0.30	Polyketide	cercosporin	Cercospora beticola
BGC0000048	0.28	Polyketide	dothistromin	Dothistroma septosporum
BGC0001219	0.26	Polyketide	shanorellin	Chaetomium globosum CBS 148.51

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002244	1.00	Polyketide	3'-methoxy-1,2-dehydropenicillide, pestalotiollide B, pestalotiollide C, 1,2-dehydropenicillide, 3-methoxy-1,2-dehydropenicillide, 1,2-epoxy-3,4-didehydropenicillide	Neopestalotiopsis clavispora
BGC0000013	0.69	Polyketide	alternariol	Aspergillus nidulans FGSC A4
BGC0002236	0.68	Polyketide	8-methyldiaporthin	Aspergillus oryzae RIB40
BGC0001542	0.67	Polyketide	cercosporin	Cercospora zeina
BGC0000161	0.66	Polyketide	isoterrein	Aspergillus terreus NIH2624
BGC0002596	0.66	Polyketide	lecanoric acid, orsellinic acid	Claviceps purpurea 20.1
BGC0000048	0.63	Polyketide	dothistromin	Dothistroma septosporum
BGC0001264	0.62	Polyketide	betaenone A, betaenone B, betaenone C	Phoma betae
BGC0002670	0.62	Other	fosfonochlorin	Fusarium oxysporum f. sp. lycopersici 4287
BGC0001219	0.60	Polyketide	shanorellin	Chaetomium globosum CBS 148.51

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 17125 - 45207:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

G7054_g10731

PKS_AT (944..1243): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 70.8%; inactive: 62.5%; Methylmalonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 92.2
inactive: 67.5
Methylmalonyl-CoA: 66.5
Methoxymalonyl-CoA: 60.0
Propionyl-CoA: 40.6
Isobutyryl-CoA: 28.7
Acetyl-CoA: 27.4
Benzoyl-CoA: 27.3
fatty_acid: 25.5
2-Methylbutyryl-CoA: 25.5
Ethylmalonyl-CoA: 24.7
CHC-CoA: 21.4
3-Methylbutyryl-CoA: 18.6
trans-1,2-CPDA: 16.1