LOCUS       BGC0002245             11093 bp    DNA     linear   CON 19-MAR-2015
DEFINITION  Cochliobolus heterostrophus C5 unplaced genomic scaffold
            COCHEscaffold_5, whole genome shotgun sequence.
ACCESSION   BGC0002245
VERSION     BGC0002245
KEYWORDS    .
SOURCE      Bipolaris maydis C5
  ORGANISM  Bipolaris maydis C5
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Dothideomycetes; Pleosporomycetidae; Pleosporales; Pleosporineae;
            Pleosporaceae; Bipolaris.
COMMENT     URL -- http://genome.jgi.doe.gov/CocheC5_3
            JGI Project ID: 42739
            The DNA was provided by Gillian Turgeon(bgt1@cornell.edu)
            The strain is available from Gillian Turgeon
            Contacts: B. Gillian Turgeon (bgt1@cornell.edu)
            Assembly and annotation done by JGI.
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376).
            ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 17:11:51
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11093
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     subregion       1..11093
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0002245"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..11093
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(34..2179)
                     /locus_tag="COCHEDRAFT_1223366"
     mRNA            complement(join(34..823,876..989,1041..1218,1272..1667,
                     1721..1790,1840..1932,1999..2179))
                     /locus_tag="COCHEDRAFT_1223366"
                     /product="hypothetical protein"
     CDS             complement(join(220..823,876..989,1041..1218,1272..1667,
                     1721..1790,1840..1932,1999..2064))
                     /codon_start=1
                     /db_xref="InterPro:IPR001128"
                     /db_xref="JGIDB:CocheC5_3_1223366"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 300.3; E-value: 4.3e-91)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="COCHEDRAFT_1223366"
                     /note="GO_function: GO:4497; iron ion binding -
                     monooxygenase activity [Evidence 20037] [PMID 5506]"
                     /product="hypothetical protein"
                     /protein_id="EMD93703.1"
                     /sec_met_domain="p450 (E-value: 1e-66, bitscore: 213.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVISLLQGLSVGQQIGTAAAISVFVLTSIVVYGCYLHPLSHVPG
                     PFLAKFSPIWGMRALYRMKFNSELQALHEKYGPVVRVAPNEVSFATLEAETAIYANQED
                     GRFSKAGTFLTLFSDLVLNAPTLITIPDPALHKRLHKVIQQAFTPQALASQEPIQKLHI
                     EKAIPDFDETADKGYHIDLADKLETMFWEIIGDLAFGEPLMAGKRPTYEKLKQLGKGSM
                     PMVEALSFMLVMPGVAPTLEMARSFLSAMPMSSQLSKLVPSTKLRDCVERKDGREDFLS
                     AIMGSEKQGLTLDADAFFSNAMGLTLAGYQTTATTLASTFYHVLRYTDAYKTLCTEIRS
                     AFNDEAEITGERLARLPFLNACIRETLRLLPPANGKTAQRTAPSCTIADTYIPAGTIVS
                     ADLYTIQRSPKYFVDPARFHPERWLEDAEKNGFNGDNRSASRPFLIGSRACIGRHMAQQ
                     SIRLIMATLLWRYDFELLDPDGFIWERDAGSSLIYTDYKLPVHVKRFQ"
     gene            3170..5597
                     /locus_tag="COCHEDRAFT_1171743"
     mRNA            join(3170..3507,3557..3848,3895..5597)
                     /locus_tag="COCHEDRAFT_1171743"
                     /product="hypothetical protein"
     CDS             join(3219..3507,3557..3848,3895..5428)
                     /codon_start=1
                     /db_xref="InterPro:IPR000092"
                     /db_xref="JGIDB:CocheC5_3_1171743"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182:Polyprenyl synthetase (Score: 209.7; E-value:
                     8.6e-64)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="COCHEDRAFT_1171743"
                     /note="GO_process: GO:8299 - isoprenoid biosynthetic
                     process"
                     /product="hypothetical protein"
                     /protein_id="EMD93704.1"
                     /transl_table=11
                     /translation="MEQLSYQSKLICSDESRHTGCFTTLPIRIHPRDDLADAASRRFVQ
                     DWAREMRDGREQSTHFSFSPVGNWSSLIYPEAIPERLGVLAYLSDLGLIHDDGGEGLSI
                     EDAQAEHGELCAALDPSDISSAAPGSRAMKTKKLVSQCMLECISLDRELGLKMLAAFRD
                     VWLAISERNSDKEAQTMEEYLKYRSDNGGMLVFWPMLQFSLGMSISEAEEALVQPIIDA
                     ATEGLLLANDYFSWEREYRELQSGQSKRIVSAVDLFIRTKGLSIDDAKEEVKRKIIAAE
                     RDFCQRRDDLYTNHPNIPLKLKRWIDCAGLAVSGNHYWCSACPRQNAWKDMSSQSLNGA
                     KRKTSHGATIGMHEAPFKKRKDSSFFGSQPSDDEPSLSEVSSYPFYKPSGLALEAPSKY
                     VSDMPSKGVRSTLIEALNTWLHVPSERLDSIMSVINTLHNASLILDDLEDNSPLRRGYP
                     ATHILFGHSQSINTANFMFVRAVQEVAQNLSPNALVALLEELKGLYLGQSWDLYWKHNL
                     ACPSEAEYVNMIDHKTGGMFRMLLRIMQAESDVTPQPDFHRLTLLFGRFFQIRDDYMNF
                     QDYTAQKGLCEDLDEGKFSYPVVYCLENHPEYRGYFLSMFRQRPTIATVNACPLSGESK
                     QYLTACLKKSGAFNKTIACLTDMERDLEFEINRLEQQTGETNPMLRLCLAKLSVKGIGR
                     IGEVSPSTSK"
     gene            5907..7762
                     /locus_tag="COCHEDRAFT_1171747"
     mRNA            join(5907..6027,6081..6590,6639..7317,7373..7762)
                     /locus_tag="COCHEDRAFT_1171747"
                     /product="hypothetical protein"
     CDS             join(5929..6027,6081..6590,6639..7317,7373..7641)
                     /codon_start=1
                     /db_xref="InterPro:IPR006094"
                     /db_xref="InterPro:IPR012951"
                     /db_xref="JGIDB:CocheC5_3_1171747"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1138:FAD linked oxidase domain protein (Score: 240.9;
                     E-value: 6.4e-73)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="COCHEDRAFT_1171747"
                     /note="GO_function: GO:16491; FAD binding - oxidoreductase
                     activity [PMID 50660]"
                     /product="hypothetical protein"
                     /protein_id="EMD93705.1"
                     /transl_table=11
                     /translation="MQLLGTLSWLYAIQASIGSSKAVTADYGSCHDACTLLSGTLSVEL
                     GGSHVSDYKHYPTIANGSSVASLFWAQQQQSAQPACLVHVYSPQDVATVISVSRSTNCP
                     FAVRGGGHSDIPGASNINGGITVNMAALSNVELHESEGLARVGAGARWGDVYKELEKSN
                     KTVVGGRLTGVGVGGLVLGGGLSHFSGLHGWACDNVRNYEVVLANGTLVIASNSSNPDL
                     YRALRGGGNSFGVVTRFDLDVFQQGPMWGGLHVWPFQPSVTSAITRGFVEFAHNAPSDP
                     HVSLFAGLGYKQGGFAWAVGQYDALGRVEPPIFTQFKDDVEVYGTAKIVSTARLTSLSD
                     LADELNQSEPAGIRSRFTTATFTADAELLILIVEFFEEQVQKALDKGLDKDQRFAPMLG
                     IQPLTQNLLRAQETRGGNVMGLRDLDAPLVVCSFGWEWSYESDDKVVIDGIKAVLDHSV
                     SAAKEKGLYHPFKYMNYAALDQDPIESYGKENIEFLKRVRAMYDPEGVFTNLVPGGHKI
                     N"
     gene            <9405..>11090
                     /locus_tag="COCHEDRAFT_1212392"
     mRNA            join(<9405..9642,9697..10026,10081..>11090)
                     /locus_tag="COCHEDRAFT_1212392"
                     /product="hypothetical protein"
     CDS             join(9405..9642,9697..10026,10081..11090)
                     /codon_start=1
                     /db_xref="InterPro:IPR001128"
                     /db_xref="JGIDB:CocheC5_3_1212392"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 256.9; E-value: 6.3e-78)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="COCHEDRAFT_1212392"
                     /note="GO_function: GO:4497; iron ion binding -
                     monooxygenase activity [Evidence 20037] [PMID 5506]"
                     /product="hypothetical protein"
                     /protein_id="EMD93706.1"
                     /sec_met_domain="p450 (E-value: 1.5e-46, bitscore: 147.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAILSSALVTIDLPVTLVSLLVGSIFYFCYLTVYRLFLSPIAHFP
                     GPKLAAWTYWYEFWYDVIAEPEYTFKIGRLHKIYGPVVRINPDEIHIADPDFYDTIYAG
                     SGRKRDKWDWITRSFGVDESLIGTLKHDEHRVRRASLSPYFSKQSVRALQPLIDRNMAI
                     LLDRLREFAKSGSPLKLDDAYAALTNDIVEDYAFGRSDHRLEAPDFDPSFRDAMLQGGK
                     AGHVLKHFTWLMDLLKKLPDSLLLKLSPAMGAYSQLQTSVKRQVAEIQHAHQMHTYDKT
                     RRTIFHEILNSKLSDYDKSTDRLWQEGEVVVAAGTITTAWALGVSTYFVLATPDILRKL
                     KTELEAAIPDPSQPLNLITLEALPFLTGVVQEGVRLSHAISHRLHRICPDETLIYQDND
                     NQREWRIPPGTPLSMTSNLVHHDERVFPDSHAFKPERWLDNARLERYLVSFGKGGRACL
                     GINLAYAELYLTLAALFRVYGTEQVKGKDDVGTLQLFETSAADLVITSDTVVPVMPEDS
                     KGLRVKVS"
ORIGIN
        1 acaagataga gcaaaaatag agcatagcgt attgtaaagt agcgatagta gcaattggat
       61 cttgtttagg cggcccacta acgtgccaaa ccaaccacag ccgtgcctac gcattccttg
      121 catcttgaga tgtaatagct gtgcaaagtg ctactccagt aaatcccaat gcaagtttca
      181 ggttctacta cgtaagatac tcgaaatcct ttgcctctcc tattgaaacc ttttaacatg
      241 cactgggagt ttgtagtcag tgtagatgag actactgcca gcgtcgcgct cccaaatgaa
      301 cccgtctgga tctagcagct cgaagtcata ccgccatagc aatgtcgcca tgatgagccg
      361 tatgctctgt tgagccatgt gtctcccgat gcatgctcgg cttccaatca aaaatggacg
      421 actagcagac ctgttatctc cattgaaccc gttcttctcc gcatcctcca accatctttc
      481 tgggtggaag cgtgctggat cgacgaaata ctttggcgat ctttgaatcg tgtataagtc
      541 agccgagaca atagtacctg ctggtatgta tgtgtctgct atagtacacg aaggggcggt
      601 gcgttgcgct gttttaccgt ttgctggcgg aagcaagcgc aaggtctcgc ggatgcaggc
      661 attgagaaat ggtaaacgtg caagcctttc gcctgtaatc tcggcttcgt cgttgaaagc
      721 agagcgtatc tcggtacaga gagttttgta agcgtctgtg tagcgcagga cgtgatagaa
      781 cgtggaggct aatgttgtag ctgtagtttg atacccggca agtctgggcg ctatcagtga
      841 cggatctttg atgaaggggg aaaggtgcga caaacgttaa acccattgca ttgctaaaga
      901 atgcatccgc gtctagcgtc aagccttgct tttcgctacc catgatggct gagaggaagt
      961 cctccctacc atctttcctt tcaacgcagc tacagatatg tcaacatgat agcacacaga
     1021 gtttgacgaa atttactcac tcgcgtagtt ttgtagatgg cacaagcttc gacagctgag
     1081 aggacattgg cattgctgaa aggaaacttc tagccatctc cagtgtcggg gctacgccgg
     1141 gcatgacaag catgaagctt aaggcttcca ccataggcat cgatccttta cctaactgtt
     1201 tcagtttttc atatgttgct tgggaaaagt tagtttacgg ttactcatta agttgtttgt
     1261 ttggtgctta cggcgttttc cagccattaa tggctcccca aatgcaaggt cgccaattat
     1321 ctcccagaac attgtctcca gtttatctgc aagatctata tggtaaccct tgtctgcagt
     1381 ttcgtcgaaa tcggggatgg ccttctcgat gtggagcttt tgaattggtt cctggcttgc
     1441 gagtgcttgg ggtgtgaagg cctgctgaat gactttgtgt agtctcttat gaagcgctgg
     1501 atctggaatt gtaataagag taggggcgtt caagacgagg tctgagaaaa gagtcaagaa
     1561 cgttccagct ttggaaaaac ggccgtcttc ttggtttgca tatatcgctg tttctgcttc
     1621 gagcgtcgca aaagacactt catttggtgc tactcgtaca acaggtccta cttgaaatca
     1681 gtccagctat ctatttagca atcacataga gggatcttgc catatttctc gtggagagct
     1741 tggagttctg aattgaattt catacgatac agagctctca taccccatat ctttcttact
     1801 cagaattttt tgcaaaccat acgatcacaa gggacccacc ggagagaact tagccaggaa
     1861 ggggcccgga acgtgtgaaa gtgggtgcag gtagcaccca tagactacaa tcgatgtcaa
     1921 aacgaatact gactacaaaa gccatattgt tagtcgtatg ccttgagcgt tctgaatgat
     1981 gagagtgcaa gaacctacaa tcgctgctgc tgtgccaatc tgctggccta cgctcagccc
     2041 ctggaggaga gaaatcactg ccatcgtggc tgtcgtaatc cttggaccga aactcgactt
     2101 tggtgttgag gaatcgtctg tagtttcatg ggatcaatga ttaattggat tgcatcctgc
     2161 atcggcgacc aggagccgtg catacatgcc atggagagtc ctggccaagg tttgttcggt
     2221 tcgcggtcta ctagtttcgg atcatgaagc ctcaccaagt taaagtgcat gttagcgttc
     2281 aagacgcgag ttggtggcgt agaagcatgc atgatcttag cgcgggaggg ctgatcatgg
     2341 ccgtttgctt ttatccggcc ggcgacgcta acgcatcctg ctccttccag aaaaacgcca
     2401 gccgcacagt agcgtaggat tcatgggcgc aatcgcgtgg gggtgggaaa tcggaccctg
     2461 gctccgcggc tctgcactgc atgcgcgcca ttttacacca acgcagctag cgccctactt
     2521 gtgtgcatcc acaacgacga tactacccat gtcggaatgc attgctccgg cggcaagaga
     2581 acgtggatga gaaactaagg acatatactg gctgccccaa actgttcggt atcgtgttca
     2641 caatccgttc gctccactca acagcatgca gaagacagct gtcaggtaag aaataagtgg
     2701 ggaatactac tatagcagct ctactaagaa tgatcctcca aaaggatttt ggacggcaca
     2761 gtagattggc ggagattgtt ggcggaaaaa catcatccac tcatacctag cgcacagcaa
     2821 gcgcttctta gaacacgact agtgaaattt cgtgctaaag tagcccaaca tgtgctctcg
     2881 atgcagcaga ctatggtctg ggttagtaga tacagatgca tgcgctgtgg atacaaacgc
     2941 tcgttggttg gtacgaagag cgtacgaata ggccgttcac agggttccaa taatgaacat
     3001 tacaaaacac cttctcccaa tgtgatgggt cctatgccca ggctcagtgt agcgctagat
     3061 aaagaaggag tggacgaacc agagcaagtt gaaccaatga tcacgtgttt ttatccaaag
     3121 cagactgtgt acaaatgctt tcgttcgatg ctgtgtacaa ccaaccacta tctccacatc
     3181 tactgtttta gccatccttt ttgacgaaac atcgcaaaat ggagcagctt tcatatcagt
     3241 ccaaactgat ttgctccgac gagtctcgtc acactggatg cttcacaaca ctccctatcc
     3301 gtatccatcc tcgagatgac ttggctgatg cagcaagtcg tcgttttgta caagactggg
     3361 ccagagagat gagagatggc cgtgagcagt ctactcattt ctcattctcg ccggtgggaa
     3421 actggtcgtc cttgatctat cccgaagcaa ttcctgagag gttgggagtc ttggcctatc
     3481 tctcggactt gggcttgatt catgatggta tttaaatctg cttcaagtta tgtcggccat
     3541 gctaacgtga gtctagacgg tggtgaaggc ttaagcattg aagacgcgca agccgagcat
     3601 ggtgaactct gtgctgcgtt agatcctagt gatatcagca gcgccgcgcc aggttcaagg
     3661 gcgatgaaaa ctaagaagct tgtgtcccag tgtatgcttg agtgtatcag tcttgaccga
     3721 gaattgggcc tgaagatgct cgcggccttc cgcgatgtct ggctcgctat tagcgagagg
     3781 aacagcgaca aggaagcgca aactatggaa gaatatttga aatatcggag cgacaatggt
     3841 ggaatgctgt aagagactga gttttgttgc aaaatctaga ctaatttttg acagagtctt
     3901 ctggccgatg cttcagttca gcctcgggat gtccatatct gaagcagaag aagcgctcgt
     3961 acagccaatc attgacgcag cgaccgaagg acttctccta gcgaatgatt acttcagctg
     4021 ggagcgcgag tatagagaac tccaatccgg tcaatcaaag aggattgtta gtgctgttga
     4081 cctgttcatc cggacgaagg gactctcaat cgacgatgca aaggaggagg tcaaacgcaa
     4141 gatcatcgcc gctgagcgcg atttctgtca gcgccgtgac gatctttaca cgaatcatcc
     4201 taacatacca ttgaagttga aacgttggat cgactgcgct gggctagctg tctcaggaaa
     4261 tcactattgg tgctcggctt gcccaaggca gaatgcgtgg aaggatatgt cttcacagag
     4321 tcttaacggg gccaaaagaa aaacatcgca tggtgcaacg atcggtatgc acgaagcacc
     4381 cttcaagaag aggaaagact cgagcttctt tggttctcag cccagcgatg atgaaccttc
     4441 actctccgag gtgtcaagct acccgtttta caagccgtcg ggacttgcat tggaggcacc
     4501 ttcaaagtac gtctccgata tgccttcaaa aggcgtccga agcacgctca tagaagctct
     4561 caacacatgg cttcacgtgc cgtctgaacg gctagactcg atcatgtctg ttatcaacac
     4621 actgcacaat gcgtcactta tccttgacga cctagaggat aattccccgc tacgaagagg
     4681 ctatccagcg acacatatcc tgtttgggca ttcccaatca atcaacactg caaacttcat
     4741 gtttgtacgc gctgtacagg aagtcgcgca gaatctaagc ccaaatgctt tggttgcact
     4801 cctcgaagaa ctcaagggct tgtatttagg ccaaagctgg gatctgtact ggaaacacaa
     4861 cctcgcgtgt ccaagtgaag ccgagtacgt caacatgatc gaccacaaga ccggtggcat
     4921 gtttcgcatg ttgctccgga tcatgcaggc agagagcgat gtgacgccgc agccggattt
     4981 ccacagactg acactgctat tcggccgatt tttccagatt cgcgacgact acatgaattt
     5041 ccaagattac acggcacaga agggactttg cgaggatctc gacgagggca aattctcgta
     5101 cccagtcgtc tactgcttgg aaaatcaccc ggaataccgc ggctattttc ttagcatgtt
     5161 ccggcaacgc cctacaattg cgaccgtcaa cgcgtgtccc ttgtcgggag agagcaaaca
     5221 gtatctgact gcttgcctga aaaagagtgg agcgttcaac aagacgattg cttgcctgac
     5281 ggatatggaa cgcgacctag aattcgagat taaccggctt gagcaacaga cgggtgagac
     5341 gaacccaatg ctgcgcttgt gtctggcaaa gctcagcgtc aaaggaattg ggagaatagg
     5401 cgaggtaagc cctagtacta gcaaatgatc gaccgggtgg ggggtcttgc tgtctggcta
     5461 gccacacccg tctgactccc atgcgggccg ctttgcccaa gcgcgctaat aacgggtcgt
     5521 acggattggg aatgaatcct acgttatcat ctctttttaa tctagattgg aagcctggac
     5581 caatgaaaca tcttcttgat gacgggtacc gcatgcctcg gtgataaaat cctactattg
     5641 tatgcatgta tggtaagcac agtgcgtgca tctttcagca tctagtctgt ggaagtgggt
     5701 atcttgggaa ccaatgcagg gagctgttcg cagctcatgt tatctcgcaa caacagtccc
     5761 gctacagtct aggcgcctct cttagccttg catggttctg taatcgcttt tttctaatcg
     5821 ccatttgggc ggccttacat atttcagtat ccaggatatc ttatttccag caaatagtgc
     5881 agacttggtg actcgaattc ctcattcttc actattggtt atacggaaat gcagctacta
     5941 ggaaccctct cttggctata cgccatccaa gcttccattg gcagcagtaa agctgtaaca
     6001 gcagattatg ggtcttgcca cgacgcagtg tgtctacgat aagtgttcag catgatagag
     6061 acagtcccta acgcatgcag tgtacccttc tttccggaac gctttctgtt gagctgggtg
     6121 ggagtcatgt gtccgattac aagcattatc ccacaattgc gaatggatcc tctgtggcat
     6181 cactcttttg ggcacagcag cagcagtctg cccaaccagc ctgccttgtt catgtctact
     6241 ctcctcaaga cgttgctacc gtcatatctg tttcccgcag cacgaattgc ccatttgctg
     6301 ttcgtggtgg cgggcactcg gatattcccg gtgcaagcaa catcaatggc ggcatcactg
     6361 tcaatatggc agcgctgagc aatgtcgaat tgcatgagag tgaaggcctt gccagagtcg
     6421 gcgcaggagc tagatggggt gacgtgtaca aagaacttga gaaatcaaac aaaaccgttg
     6481 tgggcggccg actcactgga gttggtgttg gcggactggt attgggtgga ggactaagcc
     6541 acttctcagg tctgcatggc tgggcttgtg acaatgtccg caattacgag gtaacgacat
     6601 gaacaccaca aataaagcgc aaactgatgt ccgtccaggt ggtccttgca aatggtactc
     6661 ttgtaattgc ttccaactcg tcaaatccag acctctaccg cgctttgcgc ggtggtggaa
     6721 atagttttgg cgttgtcact cgtttcgatc ttgacgtatt ccagcagggt cctatgtggg
     6781 gaggattgca tgtgtggcca ttccagccat cagtaacatc ggctatcact cgaggctttg
     6841 tcgaattcgc acacaatgct ccatctgatc cacacgtatc actcttcgct ggcttgggtt
     6901 ataagcaagg aggctttgcc tgggctgtag ggcaatatga tgctctagga agggtcgagc
     6961 ctcctatctt cacccagttc aaggatgatg tggaggtgta tggtacggca aagattgtta
     7021 gcacagccag actgacttcg ttgtcggacc tcgcggatga gctaaaccag tcagagcctg
     7081 ctggcatacg aagccgtttt acaacggcaa ctttcaccgc cgacgcagaa ctgttaatcc
     7141 taatagtaga gtttttcgaa gagcaagttc aaaaggcatt ggataagggt ttggataagg
     7201 accagcgctt tgcgccaatg ctcggaatcc agccactaac gcaaaacctc ctgagagctc
     7261 aagagacacg aggaggaaat gtcatgggcc tccgtgattt ggatgcacct ttggttggta
     7321 agtatcaccg tggataattc tttcggtggc gctgacaatc gtcactcaac agtctgttct
     7381 ttcggatggg aatggtctta tgaatctgat gacaaagtgg ttatcgacgg tatcaaagcg
     7441 gtgctggatc attctgtttc agctgctaag gaaaaaggct tatatcaccc tttcaaatac
     7501 atgaactacg ctgcattaga ccaagatcct atcgaaagct acgggaagga gaatattgag
     7561 tttttgaaaa gggtacgagc gatgtatgac ccagaaggag tgttcaccaa tctagtgcct
     7621 gggggtcaca agatcaatta atttactatt catttccaag acgcttcctt aatggagata
     7681 cggaatgggt aaaaaagaga gcggaaagat gtttctctta aagtaacatc tcatatagat
     7741 tctgacgtgc tagcgttcgc ttcggacttt gagattcaag atagcataca taggagagaa
     7801 tggaagagca ggaaaagagg tcacgagacc atttttgacg cagtcatcca cgaatcctgc
     7861 gcccagtgag gtgagaatga aaaaagtcca tacgtatccc aagagacacc attgtttgct
     7921 ccgccatcca aactgttttt gagcaaagga gatagccagg tcctcgagta acatgatagt
     7981 cggcatgaat gcaaagaaga tcagggtttt cgcaaagctc tgggatggca cgaccatctt
     8041 tgcagctacc caatgataca gcccagagat agcaaatgcc atgtacgact ggacctgacg
     8101 actcatcaat gtcccttttg gaatacatgc gatgtgcctg gcgacaaagc gactagggat
     8161 ctggagcgct ctgcggaagt tttggtgcca tacgcgattc cagaaattgt tcaaagtgta
     8221 acatgcagac catgaccctt tgagagggtg aacctcttcg ataacattcc agaaaaggcc
     8281 agaagtgaca cctaccaaac acacaatgtg gtagaaaatg tccattggcg caattgttga
     8341 tgtccaccag caacctgttg ccaaacttcg cagagcaaaa ttcatgtcga gtatactctg
     8401 ccgcccccct tcggttaacc agagaagaag agctgctgca atatcgtgaa ttacgtattg
     8461 ctccaaaatt ctcttcatcg atagtatcga gaaggatatt ttggataagc ctgctggggg
     8521 gcctgatgga aggcgtgcag tgccccaatt ccaaccaatc ccccgggttg aataggcatt
     8581 actaagacac caccgaaccc tttcgccgaa agaaagcaag ctaaaattcg agaaagtttt
     8641 ttctcccttg gtgttcctcc tagttcgtat gtgctccacg tatggatctt ctaaaacaag
     8701 tagattgaag ttcgtcaagc caacgtaaaa gactgtgcaa cgacattatc agcagctatg
     8761 actggtgaaa cactatagtg tgatctaacc tgtgccaaac gtgtagttct tggctgtgtc
     8821 aggcccgtaa ggaaatagct gaacaacgac gagacacaga accaaaaagg gaactaaaag
     8881 cagccagcgg aggcttcgct gcatgccaga gcccaacaat agtaaaaggg gtgttgagag
     8941 ccacacaagg cccacaaaat ctgctcgctc catagctatc ggtgttggga taaattcgag
     9001 gacgaattgc agtgagagag acaaggctag gtggatgttt gatgcaaatg aatgctactt
     9061 cagttgactg catacatttg tactggacgc agaatttcct atcagcgtta gcctagcgag
     9121 cttcccataa cgtactttat ctaccggggt ggcgcatgca atcgccgcat tagcggccca
     9181 ttcgttccta aatccctgca gctggcctta cagtatacta atgcatgcag tgcgtttaat
     9241 gattgaatcc ttctcgggcg caagcactac agccgactcc acaccaccaa accccccacg
     9301 ttgctgacat tttatccaag cgcctataat tcgatcacgg atttgttcac ttccatctcg
     9361 ctggttatca tcatcatcat ccaatatcac agaaactttt tgaaatggca atattgagct
     9421 ctgcgcttgt gacaatagac ctaccagtga ccttggtgtc tctgctggta ggttctatct
     9481 tttacttctg ctatctcaca gtgtatcgtc tttttctaag tccaattgcg catttcccgg
     9541 gacccaagct tgcggcatgg acctattggt acgagttctg gtacgatgtc atcgctgaac
     9601 ccgagtatac cttcaagatt ggccggcttc acaagattta tggtatgcgt agcactttaa
     9661 ttcaaatcct gccgaactac actaactgca gcgaaggacc cgtcgtccgg atcaacccag
     9721 acgaaataca catagcagac ccagacttct atgacactat ttatgctggc agtggacgta
     9781 agcgcgacaa gtgggattgg atcaccagat cttttggtgt cgatgagagt ttgatcggta
     9841 cactcaagca cgatgagcac cgtgtacgca gggcatctct ttcgccgtat ttctccaagc
     9901 agagcgtacg agcactgcag cccctgatag accgaaacat ggcaattctt ctggaccgtc
     9961 ttcgcgagtt tgccaaatct ggttcaccac taaagctgga tgatgcttac gcagcactga
    10021 ccaatggtaa gagaccctcg aatctataaa ctggacattg attttaatct tgctttacag
    10081 acattgttga ggactatgcc tttgggagaa gcgatcaccg tctggaggct ccagactttg
    10141 acccgtcgtt cagagacgca atgctgcagg gcggcaaagc cgggcatgtg ctgaagcatt
    10201 tcacatggtt gatggacttg ttgaagaagc tgcctgactc actactacta aaattgagcc
    10261 ccgcaatggg cgcgtactcg cagcttcaga ctagcgtgaa gcgtcaagtc gctgagatac
    10321 agcacgcaca tcaaatgcac acctacgaca agacacgccg taccatcttt cacgagatcc
    10381 tcaatagcaa gctttcggac tatgataagt ctacagatcg tctctggcaa gagggcgaag
    10441 tggttgttgc tgctggaacc atcactactg cctgggcgct gggcgtgtcg acgtactttg
    10501 tgctcgccac cccggatatt ctgcgtaagc tcaagactga gttggaggct gcaatccccg
    10561 atccttcgca gccactcaat ctcatcacgc ttgaggctct tcccttcctt actggcgtgg
    10621 tccaagaagg cgtgcgtcta agccacgcta tctcacaccg cttgcaccgc atctgccctg
    10681 atgagacact catctaccag gacaatgaca accaacgcga atggagaatt ccacctggaa
    10741 cacccctaag catgactagc aacctagttc atcatgatga acgtgtcttc ccggactcgc
    10801 acgcgttcaa gcccgagcgc tggcttgata acgcccgcct cgagcgttat ctggtatcgt
    10861 ttggaaaggg tggaagagcg tgtctgggca tcaaccttgc ttatgcagag ctctatctga
    10921 cattggcggc gctcttcaga gtatacggta ccgagcaggt caaggggaag gacgatgttg
    10981 ggacgttgca gttgtttgag acaagtgccg ctgacttggt gattacaagt gacactgttg
    11041 tccctgtcat gcccgaggac tccaaggggt tacgagtaaa ggtttcttag act
//
