BGC0002249: phaeospelide A biosynthetic gene cluster from Arthrinium phaeospermum
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Location: 4,443,220 - 4,453,403 nt. (total: 10,184 nt).
This entry is originally from NCBI GenBank QYRS01000001.1, but has been modified (see Modifications tab for details).

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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Gene details
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General
Compounds
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Biosynthesis
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General information about the BGC

MIBiG accession | BGC0002249
Short description | phaeospelide A biosynthetic gene cluster from Arthrinium phaeospermum
Status | Quality: questionable The quality level of this entry. Status: active The status of this entry. Completeness: unknown Whether the entry covers everything needed for the pathway producing the compound(s)

Biosynthetic class(es)

- PKS (Unknown)

Loci
QYRS01000001.1
4443220 - 4453403
via Heterologous expression
Compounds

- phaeospelide A

Species Arthrinium phaeospermum [taxonomy]
References

- [1] The Discovery of Fungal Polyene Macrolides via a Postgenomic Approach Reveals a Polyketide Macrocyclization by trans-Acting Thioesterase in Fungi. Morishita, Y et al., Organic Letters (2019) DOI:10.1021/acs.orglett.9b01674
- [2] The Discovery of Fungal Polyene Macrolides via a Postgenomic Approach Reveals a Polyketide Macrocyclization by trans-Acting Thioesterase in Fungi. Morishita Y et al., Org Lett (2019) PMID:31180682

Chemical products information
phaeospelide A Evidence:
Copy SMILES
Chemical database entries
NPAtlas
List of genes involved in compound(s) production

Identifiers | Position | Product | Functions | Evidence | Extra
--- | --- | --- | --- | --- | ---
apmlB | 4443220 - 4444200 (-) |  |  |  | copy AA seq copy Nt seq
apmlA | 4445569 - 4453403 (+) |  |  |  | copy AA seq copy Nt seq

Biosynthesis information

No biosynthesis information available for this record.

Annotation changelog

#### Entry version: 1

Date
Changes
Submitters
Reviewers
2022-09-15
Entry added

- (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

- (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

2022-09-15
Fix locus

- (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

- (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

2022-09-15
Add gene annotations

- (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

- (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

2022-09-15
Fix cluster coordinates

- (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

- (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

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Modifications to original record

- apmlA was added
- apmlB was added