LOCUS       BGC0002256             23896 bp    DNA     linear   PLN 09-MAR-2021
DEFINITION  TPA_asm: Fusarium equiseti genomic sequence.
ACCESSION   BGC0002256
VERSION     BGC0002256
KEYWORDS    .
SOURCE      Fusarium equiseti (Gibberella intricans)
  ORGANISM  Fusarium equiseti
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Sordariomycetes; Hypocreomycetidae; Hypocreales; Nectriaceae;
            Fusarium; Fusarium incarnatum-equiseti species complex.
COMMENT     THIRD PARTY DATABASE: This TPA record uses data from
            DDBJ/EMBL/GenBank entry QOHM01000003.1.
            ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2024-10-17 17:12:38
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 23896
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..23896
                     /db_xref="taxon:61235"
                     /mol_type="genomic DNA"
                     /organism="Fusarium equiseti"
     misc_feature    1..23896
                     /note="fusarochromene biosynthetic gene cluster; fsc BGC"
     subregion       1..23896
                     /aStool="mibig"
                     /contig_edge="True"
                     /label="NRPS, other"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..23896
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(<465..>3536)
                     /gene="fscA"
     mRNA            complement(<465..>3536)
                     /gene="fscA"
                     /product="NRPS-like oxidoreductase"
     CDS             complement(465..3536)
                     /NRPS_PKS="Domain: AMP-binding (33-429). E-value: 2.9e-87.
                     Score: 284.7. Matches aSDomain:
                     nrpspksdomains_fscA_AMP-binding.1"
                     /NRPS_PKS="Domain: PKS_PP (578-632). E-value: 3.1e-07.
                     Score: 22.5. Matches aSDomain:
                     nrpspksdomains_fscA_PKS_PP.1"
                     /NRPS_PKS="Domain: NAD_binding_4 (684-902). E-value:
                     3.2e-37. Score: 119.8. Matches aSDomain:
                     nrpspksdomains_fscA_NAD_binding_4.1"
                     /codon_start=1
                     /gene="fscA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score: 289;
                     E-value: 9.5e-88)"
                     /gene_kind="biosynthetic"
                     /product="NRPS-like oxidoreductase"
                     /protein_id="DAD54574.1"
                     /sec_met_domain="AMP-binding (E-value: 1e-103, bitscore:
                     336.4, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 5.7e-38, bitscore:
                     119.8, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEIQVPESHWKHFLEWNRPLPPTKQTCIHHEIEAQAAAQPTKVA
                     VASTVASLTYGDLNGMATRIASDLKRHGICPEKIVPLCFDKSPSMIVAMLAVLKAGGAF
                     VALDPKAPSSRINVIMQQVNAKIVVTESKHRHLFSDYQIIEISTYDFMLPQTTDNYPST
                     RPSHPNDAAYLIFTSGSTGKPKAVVVEHQSFCSGMARHAPAQFIDRHSRVLQFASYTHD
                     ACIVEILTTLCMGGTICSPSEHERVNGLVQFINSQSVNWAVLTPSFITSIDHDEISTLE
                     TVVLAGERTLQSNISSWAGSVRLLTGYGVSECSVVTTISSPADENRSASHIGMPAGGVC
                     WIVNPDDPDKLLPIGEVGEIIIEGPTVARGYLGNPEATERAFIQPPVWLHHVLEDPDHS
                     SRLYRTGDLGRYNPDGSLDFVSRIGSQVKILGRRIELGEIEHHISNHPFVRQCMVQLPS
                     MGDYHNQLVAVLELHTKPYVSLGDGSESNDLVQCNADTHKIESFLRTKVPEYMVPSFWF
                     TIDHFPRLPSAKLDRNKVADLIAQLRLIGDASYGVVPEDDVIGRQIAREVTTMRLPQGQ
                     VLDPSISFQDTPLRKAGIDSIKAISLRKTLQRLWGVNIPVSCFMEQTARPTSIANHVRS
                     AQDQGQGEYILPEPDLKGALDGLKRSLDVSMTTAPTRSSVSSGGKLSTLLTGGAGYLGQ
                     EILKTLLTAGRRVIVLVRACNISEGRKRFHNLPWWRSDFEDKLDVCLGDLSQPNLGIDQ
                     DLMERLGGHVQAVIHNGARVHWTECASDLWSVNVDATVTLLQFALSSSSVQRFVYISGG
                     SAIGDSSDEWLVNARDGYSKTKLLAQALVEHCATKSEDLQLGLGMSIVKPGFIIGGPET
                     GVANPSDYLWRYVASVVELGVYDESTTRARVPVSTLPLVAETIIRQISTASNRKHVEII
                     DESLRERDIWEVLRTLGYTLRPVSHRSWVTTIQDAMNKRREDHYLWPLASILEQQAYCL
                     GDEKIQLGCKLKKKEYLKNAIQRNIQSLVSQGFI"
     aSDomain        complement(831..1484)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_fscA_NAD_binding_4.1"
                     /evalue="3.20E-37"
                     /label="fscA_NAD_binding_4.1"
                     /locus_tag="fscA"
                     /protein_end="902"
                     /protein_start="684"
                     /score="119.8"
                     /tool="antismash"
                     /translation="LTGGAGYLGQEILKTLLTAGRRVIVLVRACNISEGRKRFHNLPWW
                     RSDFEDKLDVCLGDLSQPNLGIDQDLMERLGGHVQAVIHNGARVHWTECASDLWSVNVD
                     ATVTLLQFALSSSSVQRFVYISGGSAIGDSSDEWLVNARDGYSKTKLLAQALVEHCATK
                     SEDLQLGLGMSIVKPGFIIGGPETGVANPSDYLWRYVASVVELGVYDESTTRARV"
     aSModule        complement(831..3437)
                     /complete
                     /domains="nrpspksdomains_fscA_AMP-binding.1"
                     /domains="nrpspksdomains_fscA_PKS_PP.1"
                     /domains="nrpspksdomains_fscA_NAD_binding_4.1"
                     /locus_tags="fscA"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(1404..1487)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_fscA_0005"
                     /evalue="6.70E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="fscA"
                     /protein_end="711"
                     /protein_start="683"
                     /score="15.5"
                     /tool="antismash"
                     /translation="LLTGGAGYLGQEILKTLLTAGRRVIVLV"
     aSDomain        complement(1641..1802)
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_fscA_PKS_PP.1"
                     /evalue="3.10E-07"
                     /label="fscA_PKS_PP.1"
                     /locus_tag="fscA"
                     /protein_end="632"
                     /protein_start="578"
                     /score="22.5"
                     /tool="antismash"
                     /translation="DPSISFQDTPLRKAGIDSIKAISLRKTLQRLWGVNIPVSCFMEQT
                     ARPTSIANH"
     CDS_motif       complement(2217..2282)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_fscA_0004"
                     /evalue="1.60E-07"
                     /label="NRPS-A_a8"
                     /locus_tag="fscA"
                     /protein_end="440"
                     /protein_start="418"
                     /score="23.7"
                     /tool="antismash"
                     /translation="FVSRIGSQVKILGRRIELGEIE"
     aSDomain        complement(2250..3437)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_fscA_AMP-binding.1"
                     /evalue="2.90E-87"
                     /label="fscA_AMP-binding.1"
                     /locus_tag="fscA"
                     /protein_end="429"
                     /protein_start="33"
                     /score="284.7"
                     /tool="antismash"
                     /translation="EAQAAAQPTKVAVASTVASLTYGDLNGMATRIASDLKRHGICPEK
                     IVPLCFDKSPSMIVAMLAVLKAGGAFVALDPKAPSSRINVIMQQVNAKIVVTESKHRHL
                     FSDYQIIEISTYDFMLPQTTDNYPSTRPSHPNDAAYLIFTSGSTGKPKAVVVEHQSFCS
                     GMARHAPAQFIDRHSRVLQFASYTHDACIVEILTTLCMGGTICSPSEHERVNGLVQFIN
                     SQSVNWAVLTPSFITSIDHDEISTLETVVLAGERTLQSNISSWAGSVRLLTGYGVSECS
                     VVTTISSPADENRSASHIGMPAGGVCWIVNPDDPDKLLPIGEVGEIIIEGPTVARGYLG
                     NPEATERAFIQPPVWLHHVLEDPDHSSRLYRTGDLGRYNPDGSLDFVSRIGSQVKI"
     CDS_motif       complement(2391..2480)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_fscA_0003"
                     /evalue="2.70E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="fscA"
                     /protein_end="382"
                     /protein_start="352"
                     /score="45.3"
                     /tool="antismash"
                     /translation="PIGEVGEIIIEGPTVARGYLGNPEATERAF"
     CDS_motif       complement(2964..3023)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_fscA_0002"
                     /evalue="3.40E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="fscA"
                     /protein_end="191"
                     /protein_start="171"
                     /score="31.8"
                     /tool="antismash"
                     /translation="AYLIFTSGSTGKPKAVVVEH"
     CDS_motif       complement(3213..3254)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_fscA_0001"
                     /evalue="2.70E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="fscA"
                     /protein_end="108"
                     /protein_start="94"
                     /score="14.3"
                     /tool="antismash"
                     /translation="LAVLKAGGAFVALD"
     gene            <4464..>6009
                     /gene="fscB"
     mRNA            join(<4464..4490,4563..4984,5034..>6009)
                     /gene="fscB"
                     /product="putative TF"
     CDS             join(4464..4490,4563..4984,5034..6009)
                     /codon_start=1
                     /gene="fscB"
                     /product="putative TF"
                     /protein_id="DAD54575.1"
                     /transl_table=11
                     /translation="MECHYSEAQLASLLLPYLERFDENAINGLASELKSHGISVYAAAG
                     FDPNVGSSLTFKKEVPPSDTSILEDVDHVNLYSEQDNFHLSMLDMMDFHTPDIMDIGLF
                     TDVQHEGDPVDELELSSDTRSSLSPSSHNTTTGHETGLSSVTPPQSYWTSDNLVSTRAL
                     PTTGDKQLSPQRRTEIADISSLPTCQQISLEPQCHSVMEAPCHGKEVTKRNKRSRTEAQ
                     EASNSPCASSTADSQTNPAPLRLRSVFGPGTKYNLSHKSLHEISDISENCIRPDLVEFL
                     EERLTRWKKTGFWHQDQIPEPTASGAGREKLIDAYSCICRLESRMKDDQILNRVAVVML
                     HTAYEQACQEWRHAGTHQRKGRGRGDATTVIDEILSELHEDWDVGDRKRYHRSRFHDKK
                     RFGKRWLVLIKSLGVGILLCSSQRLASAVYVLPFQITLFILDTNLSESAATRRFLPATC
                     CRRWFAVSNSLRLNSC"
     gene            <6648..>11009
                     /gene="fscC"
     mRNA            <6648..>11009
                     /gene="fscC"
                     /product="NRPS-like tryptophan epimerase"
     CDS             6648..11009
                     /NRPS_PKS="Domain: AMP-binding (16-409). E-value: 2.3e-84.
                     Score: 275.2. Matches aSDomain:
                     nrpspksdomains_fscC_AMP-binding.1"
                     /NRPS_PKS="Domain: Epimerization (637-919). E-value:
                     3.5e-19. Score: 59.7. Matches aSDomain:
                     nrpspksdomains_fscC_Epimerization.1"
                     /codon_start=1
                     /gene="fscC"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     274.1; E-value: 3e-83)"
                     /gene_kind="biosynthetic"
                     /product="NRPS-like tryptophan epimerase"
                     /protein_id="DAD54576.1"
                     /sec_met_domain="AMP-binding (E-value: 2.8e-95, bitscore:
                     308.6, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 3.5e-34, bitscore:
                     107.6, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLLDIMDSHCIHTLVDQRASSQPLEPAVETYDVSLSYGELSAMS
                     SKLSQYLVSLGIYPEAKVVLMMEPCASYVVSTISVLKAGATFVPLDATQPTKRLAQLIK
                     DIKPFIIITSIEVQDKARSLYDNVLVVDQTPSPWQDAPLKTGAACHVNGSNAAYIIFTS
                     GSTGLPKGVIIEHGAFSASALARGNLTGLSLGSRVLQYAAHTFDVSVDEILTTLIHGGC
                     VCIPSKADRLLLEPAINRLQVNHALLTPTSAKVLDPDAVPSLKTLQLGGELLPDDLIRK
                     WCSRVRLFNVYGPTEASVACIMSEKSQKNIFGNVIGFPVGSVCRIVDPDDHNQLVAPGV
                     VGELLIGGRILARGYLNDNIRTASSFIESPPWTSDDNATRFYKTGDLAKIDHYGSVTIL
                     GRKDNQVKIRGQRINVEEIETTLLATHLIRNCVVELPKKGPLANKLVAIVSTTSDTPHC
                     KHPPPAAFSEQLQASVSTLDGLLRTRLHDALQDHLTSAMIPKRWIRMTSLPETTSGKVN
                     RKEIRRWLERMDASVLQSVSLSNVESTGSRQSTRHKIQPEHEKILCRILGVNPTLLKPH
                     LSFIQNGGDSIAAIELCRLGREIGISFWISSVLSDNSLEKLFHTSKSRFTKTIAHESQP
                     GTPFPLSPVQRFFFDVVGNEHSSFTQYVTLQLKNRISIAQLERVIDRLVSAHPMLRARF
                     HSENDTWLQSIPERISGSYSIFHHHGVGPPNHELMQPPVLSLASDPVLNVRLWDFDSGP
                     QQLQLIAHHLVVDLVSWRIILDDLSKALRHERLPSAGMSFQSWCALQKEYAKTLDPKLV
                     LPIPIISDNCAYWYPSVAQQENKHGMTETSTFSFDMLTFNSLLVGSLSKTQPIELMVGS
                     FYTAFAKVFSDRETPTVFVESHGREPWQTGIDILQTVGWFTTAYPIHVPAQKASDLNES
                     TLHTMRARRSIPANGHQYWCHRFLEQYEPDERKRSAPLEFVINFAGQFQQLSQADLPFR
                     VMSTVGEETAEPQARRLSLFDIFISVEGDQLHFNISFPSWVSHRDKIHHLSTVWKDVLE
                     SAGVFSERPVLDPEPIDMLRELWHDCSLKDIDEVYWASDAQNHMLNSSSRHPSFYTVVG
                     RWRLKCNTGAPLTDAFRVQDAWKRVITNHRALRTIFIPGDRKCGFLAVVMEQSFPMVLT
                     GGASDTSDTNGTTRFFGLQSNERAIHLPHRIILHESNDGSILFSLEISHTVIDATSRSI
                     LMNELLDALVDIDLVPDDSHYHEYIESRDALYALSPPCQPPPCIFPPDLHCSDSAGSQL
                     STHVVELSQTSTANMSQICSQHGITMSSLLFLSWTLVLSNYTSSDDISFAYVASGRSMD
                     VPGIERFVGLYVDLLILNIDTSGSDCLLDLALRVQQMSAGSSLHQHNQIPACRNPKNGR
                     FDGQVNTMVNIRNVGIDSLRLERHDFELLLDSFEDPWDVRFFNTSCPFLPI"
     aSDomain        6696..7874
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_fscC_AMP-binding.1"
                     /evalue="2.30E-84"
                     /label="fscC_AMP-binding.1"
                     /locus_tag="fscC"
                     /protein_end="409"
                     /protein_start="16"
                     /score="275.2"
                     /tool="antismash"
                     /translation="DQRASSQPLEPAVETYDVSLSYGELSAMSSKLSQYLVSLGIYPEA
                     KVVLMMEPCASYVVSTISVLKAGATFVPLDATQPTKRLAQLIKDIKPFIIITSIEVQDK
                     ARSLYDNVLVVDQTPSPWQDAPLKTGAACHVNGSNAAYIIFTSGSTGLPKGVIIEHGAF
                     SASALARGNLTGLSLGSRVLQYAAHTFDVSVDEILTTLIHGGCVCIPSKADRLLLEPAI
                     NRLQVNHALLTPTSAKVLDPDAVPSLKTLQLGGELLPDDLIRKWCSRVRLFNVYGPTEA
                     SVACIMSEKSQKNIFGNVIGFPVGSVCRIVDPDDHNQLVAPGVVGELLIGGRILARGYL
                     NDNIRTASSFIESPPWTSDDNATRFYKTGDLAKIDHYGSVTILGRKDNQVKIR"
     aSModule        6696..9404
                     /domains="nrpspksdomains_fscC_AMP-binding.1"
                     /domains="nrpspksdomains_fscC_Epimerization.1"
                     /incomplete
                     /locus_tags="fscC"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       6882..6920
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_fscC_0001"
                     /evalue="5.10E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="fscC"
                     /protein_end="91"
                     /protein_start="78"
                     /score="13.5"
                     /tool="antismash"
                     /translation="SVLKAGATFVPLD"
     CDS_motif       7116..7175
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_fscC_0002"
                     /evalue="1.30E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="fscC"
                     /protein_end="176"
                     /protein_start="156"
                     /score="30.0"
                     /tool="antismash"
                     /translation="AYIIFTSGSTGLPKGVIIEH"
     CDS_motif       7659..7745
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_fscC_0003"
                     /evalue="1.10E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="fscC"
                     /protein_end="366"
                     /protein_start="337"
                     /score="40.1"
                     /tool="antismash"
                     /translation="PGVVGELLIGGRILARGYLNDNIRTASSF"
     CDS_motif       7842..7904
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_fscC_0004"
                     /evalue="1.90E-09"
                     /label="NRPS-A_a8"
                     /locus_tag="fscC"
                     /protein_end="419"
                     /protein_start="398"
                     /score="29.7"
                     /tool="antismash"
                     /translation="LGRKDNQVKIRGQRINVEEIE"
     aSDomain        8559..9404
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_fscC_Epimerization.1"
                     /evalue="3.50E-19"
                     /label="fscC_Epimerization.1"
                     /locus_tag="fscC"
                     /protein_end="919"
                     /protein_start="637"
                     /score="59.7"
                     /tool="antismash"
                     /translation="PFPLSPVQRFFFDVVGNEHSSFTQYVTLQLKNRISIAQLERVIDR
                     LVSAHPMLRARFHSENDTWLQSIPERISGSYSIFHHHGVGPPNHELMQPPVLSLASDPV
                     LNVRLWDFDSGPQQLQLIAHHLVVDLVSWRIILDDLSKALRHERLPSAGMSFQSWCALQ
                     KEYAKTLDPKLVLPIPIISDNCAYWYPSVAQQENKHGMTETSTFSFDMLTFNSLLVGSL
                     SKTQPIELMVGSFYTAFAKVFSDRETPTVFVESHGREPWQTGIDILQTVGWFTTAYPIH
                     V"
     CDS_motif       8637..8732
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_fscC_0005"
                     /evalue="2.00E-05"
                     /label="C2_LCL_024-062"
                     /locus_tag="fscC"
                     /protein_end="695"
                     /protein_start="663"
                     /score="17.0"
                     /tool="antismash"
                     /translation="TLQLKNRISIAQLERVIDRLVSAHPMLRARFH"
     CDS_motif       8916..8978
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_fscC_0006"
                     /evalue="3.10E-10"
                     /label="NRPS-E2"
                     /locus_tag="fscC"
                     /protein_end="777"
                     /protein_start="756"
                     /score="32.3"
                     /tool="antismash"
                     /translation="QLIAHHLVVDLVSWRIILDDL"
     CDS_motif       9354..9404
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_fscC_0007"
                     /evalue="1.00E-06"
                     /label="NRPS-E5"
                     /locus_tag="fscC"
                     /protein_end="919"
                     /protein_start="902"
                     /score="21.0"
                     /tool="antismash"
                     /translation="DILQTVGWFTTAYPIHV"
     CDS_motif       10290..10343
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_fscC_0008"
                     /evalue="2.90E-03"
                     /label="C3_DCL_135-156"
                     /locus_tag="fscC"
                     /protein_end="1232"
                     /protein_start="1214"
                     /score="10.4"
                     /tool="antismash"
                     /translation="HTVIDATSRSILMNELLD"
     CDS_motif       10635..10706
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_fscC_0009"
                     /evalue="1.90E-05"
                     /label="C5_DCL_263-294"
                     /locus_tag="fscC"
                     /protein_end="1353"
                     /protein_start="1329"
                     /score="17.1"
                     /tool="antismash"
                     /translation="DISFAYVASGRSMDVPGIERFVGL"
     gene            <11464..>12798
                     /gene="fscD"
     mRNA            join(<11464..11754,11815..12384,12445..>12798)
                     /gene="fscD"
                     /product="tryptophan 2,3-dioxygenase"
     CDS             join(11464..11754,11815..12384,12445..12798)
                     /codon_start=1
                     /gene="fscD"
                     /product="tryptophan 2,3-dioxygenase"
                     /protein_id="DAD54577.1"
                     /transl_table=11
                     /translation="MDDLMTNIEHYHVSLTTGFLPPSAPLTHLPQKYYEPWETLASSLP
                     TRIRDGSLRHQASLIPLLETDFLVTDAEWQRAYVVLGFLSNAFIFCQYPPSERLPLSLA
                     EPMMNVSCYLGLPCVPTYSGQTLWNHCYISEIQLPVLEQVNTLVSFTGSREESAFFGIS
                     VAIEKCGSPLIRTLLHAMAAAEAGNEKELTACLSKAMITIDSITSILPQLYGRCSPSFF
                     YNTLRPFLEGTQDLKSAGLPNGVFFETKNGGSYQKFRGPSNAQSSLFCFIDIALGIEHN
                     DNSFLTEMRQYMPGPHRDFLARVEAIDSVRHFISANPDASQLQEAYEGCVLALARFRQI
                     HIRLVARYIVIPSNGTKTADQSSMGNGLSSEPVSIAGAQGTGGTKPVEFLKVIRNDVLE
                     SLQAS"
     gene            <12973..>14631
                     /gene="fscE"
     mRNA            join(<12973..13204,13276..13817,13873..>14631)
                     /gene="fscE"
                     /product="putative tryptophan 6-hydroxylase"
     CDS             join(12973..13204,13276..13817,13873..14631)
                     /codon_start=1
                     /gene="fscE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 289.2; E-value: 9.9e-88)"
                     /gene_kind="biosynthetic-additional"
                     /note="P450"
                     /product="putative tryptophan 6-hydroxylase"
                     /protein_id="DAD54578.1"
                     /sec_met_domain="p450 (E-value: 2.5e-57, bitscore: 184.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVSSLNNLGVLLPIEGVIILVFVLSCFSLAIKRLYFSPLAKFPGP
                     KLAALTMWYEFYYDVVKRGNYFRQIAKMHDQYGPVVRINPFELHVNDPTFYPILYSSST
                     KKRDKWSWAAGMFGNNTSVFSTVPHDHHRIRRAALNPLFSRTAIKQLEPTIKCQMHELS
                     RRLDSFCESGMVLDLGLAFTVFAADVISAYCFGEPFGLLQDPDFAPEWVETVAAPSELG
                     HLIKQFPWALGLFRLLPRSLIGVISPAIVRLYTIQEWMSLNVQSLISKRHDDHSSSAKS
                     CVFEALLRSKLPASEKTVDRLKGEGQTLIGAGTLTTANVLKHVVFHTLDNPDRLHALAA
                     ELEAEFPDPNEDVSLDRLERLPLLTAYIKEALRLGYGVTHRLQLLADEPLHCNGMIIPP
                     RTPVGMTSIFMHDDPTVFPNPREFDPDRWLGEVEDRRHLERCFVPFSKGTRMCLGMHLA
                     WAEIYIVIATVFRSYSFQLHDTDRSHIEMAHDFFDPAPKLDSKGLRVTVQRK"
     gene            <15104..>16851
                     /gene="fscF"
     mRNA            join(<15104..15169,15230..15826,15904..>16851)
                     /gene="fscF"
                     /product="FscF"
     CDS             join(15104..15169,15230..15826,15904..16851)
                     /codon_start=1
                     /gene="fscF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 292; E-value: 1.4e-88)"
                     /gene_kind="biosynthetic-additional"
                     /note="P450"
                     /product="FscF"
                     /protein_id="DAD54579.1"
                     /sec_met_domain="p450 (E-value: 1.3e-55, bitscore: 178.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELSLSFPVSWLCALFTAIALYCIAVAFYRLFLHPLAKFPGPFLW
                     KISIWPTVWQCAHGKRHLDLLAAHKRHGPVVRIGPNMLSYNTGSAARTIYASRHANVRK
                     SDFHLTVDASVSAPSLFSIVDREKHAFRRRVVSQAFTEKAMMDASEFYLKYMKVFLDVL
                     HDKVGTGWTKVDIQEHATWWTSDTMGDLSLGRSFNCLTEPTFRHAIPMMRNGLRYIYWA
                     GHLPFRDLVDYILAHPILSRYGGQSAVDNRNYFDFCETAIQERIKEEQDALAAGADEES
                     RRKDYIHYLLAAVDPETGEKLTKNELESDASLLLAAGGDAMSNAIAGIMFYLARHDFAR
                     DRATAEIRHQFASAEDIRQGPGLAACTYLEACILESMRMAPPVATSPLERVTVGNGIEV
                     DGHWFPAGITLGVCFYALNFNETIHKDPYRFRPERWLSSEEGITAEDVQQSKSNFFPFS
                     AGHRHCPARNLASRNLKVFIANMLWHFDLRPATSLGVNESSGEEGQTGLFCIEDALISI
                     ADGPVLEFKARLGYNASSS"
     gene            complement(<17010..>18317)
                     /gene="fscG"
     mRNA            complement(<17010..>18317)
                     /gene="fscG"
                     /product="DMATS-type prenyltransferase"
     CDS             complement(17010..18317)
                     /codon_start=1
                     /gene="fscG"
                     /gene_functions="biosynthetic (rule-based-clusters) indole:
                     dmat"
                     /gene_kind="biosynthetic"
                     /product="DMATS-type prenyltransferase"
                     /protein_id="DAD54580.1"
                     /sec_met_domain="dmat (E-value: 2e-100, bitscore: 326.1,
                     seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNDTTSKECPSGPSAWSIASQWVDPGAQSAPWWKLIGSQLCLLAQ
                     EARYPIEKQFEILLFLYAKVLPRVGPLNKGEKFNSPSRYTSLLTDDGTPFEYSWKWNNS
                     TSSPDIRYCIEAIGSHTGSSTDPYNYLETEKLLTQDLASCVPGLDLTWFHHFVKAFGID
                     QRQMASNNPDAPKANMFVAFEHVQKGVVVKAYFLPAAEAGSGGPPTFETFASATRGVLN
                     NTAALDASLDFVKNNEMGIDLVPDMLAVDCVDPNKSRLKLYVSTTATSFASIVSVMTLG
                     GKITDVDRGIKELEVLLSFALGKETPISRDDELNVQSVFDKGLAHDFDLYGRMTYYFDI
                     APSSKLPDVKLYIPVIRFGRSDEAVASGLGQYLRLRQRDQFHDGFMRALGSIGAGHPEG
                     SGHRLQTYLAVAFQRDGSLAITSYINPGVYHDDLKG"
     gene            <18565..>19522
                     /gene="fscH"
     mRNA            join(<18565..18698,18757..>19522)
                     /gene="fscH"
                     /product="kynurenine formamidase-like hydrolase"
     CDS             join(18565..18698,18757..19522)
                     /codon_start=1
                     /gene="fscH"
                     /product="kynurenine formamidase-like hydrolase"
                     /protein_id="DAD54581.1"
                     /transl_table=11
                     /translation="MEQHFEHLSCIPYLENTEASRYQTLDIWIPTRHQHGDSTHGYWII
                     FIHGGAWRDPDINATNFAEKAVLDLITSGVSQIIEGIASINYRLSPRTPSQPVPSGGHV
                     GGEQQAMHPDHLNDVISGIEYLQRKFRFGNRYILTGHSCGATLAYQTLIRQTMDKTETH
                     AAPHAIIGVAGLYDLPLLRDMDPMPPMCHQFLLAAFGSDETLWRDVSPATYGDFERLWP
                     TGKLAVLVYCEDDEYVSPAQLNTMYHALEIWGEKEGRLVKTLKLPGGHDEVWRTGSGLA
                     SCVEKSINYLQDLSVSEA"
     gene            complement(<19841..>20675)
                     /gene="fscI"
     mRNA            complement(join(<19841..20547,20606..>20675))
                     /gene="fscI"
                     /product="oxidoreductase"
     CDS             complement(join(19841..20547,20606..20675))
                     /NRPS_PKS="Domain: PKS_KR (22-113). E-value: 1.9e-09.
                     Score: 29.6. Matches aSDomain:
                     nrpspksdomains_fscI_PKS_KR.1"
                     /codon_start=1
                     /gene="fscI"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     118; E-value: 8e-36)"
                     /gene_kind="biosynthetic-additional"
                     /product="oxidoreductase"
                     /protein_id="DAD54582.1"
                     /transl_table=11
                     /translation="MFDGTTQAQDVAAAFQGEISGKTFVITGVSFGGLGAAVCEALAPY
                     GPGHLIITGRDIQRPQEVAKALIAQYPDLQISVIQMDLALPKSVENAAQEIKKVASRVH
                     VLVNNAGVMCIPDRTLTEKGIEAHLAINYVGHFLLTKLLAEQMSSTDSSPVQGRVINVS
                     SSAHTVSPFRFGDPHFIGSSDLLPDEEPSREACKAFGIPWETSYSPLVAYAQSKTAVIL
                     HAKAISSGVLRDGITAFSVNPGGKWNPTILYVLCHC"
     aSDomain        complement(join(20279..20547,20606..20609))
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_fscI_PKS_KR.1"
                     /evalue="1.90E-09"
                     /label="fscI_PKS_KR.1"
                     /locus_tag="fscI"
                     /protein_end="113"
                     /protein_start="22"
                     /score="29.6"
                     /tool="antismash"
                     /translation="TFVITGVSFGGLGAAVCEALAPYGPGHLIITGRDIQRPQEVAKAL
                     IAQYPDLQISVIQMDLALPKSVENAAQEIKKVASRVHVLVNNAGVM"
     CDS_motif       complement(20453..20527)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_fscI_0001"
                     /evalue="2.80E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="fscI"
                     /protein_end="55"
                     /protein_start="30"
                     /score="20.0"
                     /tool="antismash"
                     /translation="FGGLGAAVCEALAPYGPGHLIITGR"
     gene            complement(<22017..>23426)
                     /gene="fscJ"
     mRNA            complement(join(<22017..22344,22392..22566,22616..>23426))
                     /gene="fscJ"
                     /product="putative aromatic peroxidase"
     CDS             complement(join(22017..22344,22392..22566,22616..23426))
                     /codon_start=1
                     /gene="fscJ"
                     /product="putative aromatic peroxidase"
                     /protein_id="DAD54583.1"
                     /transl_table=11
                     /translation="MKWLHLLSVVACVADEVYAFPSHLHGAVGHLTASRLSSVVDEAVR
                     SAHEKRLLFDAGNEPIDVTGKHEFIPPNFEKGDQRGPCPGLNALANHGYIKRNGVTNLV
                     ETIGAINKVYGMGIDLATILTTMGVVFVGNPLSLNPGFSIGSTPKGNDNILGNLVGLLG
                     KPRGLVGSHNIIEGDSSNTRADLYVTGDASTMAMDQFESFYDMASDEGTYDFDTFAERA
                     KIRFHETIETNPDFYYGPFTGMIVRNAGYFFACRMLSNHTKGSHEDIMDQATLRSFFAV
                     QKEGDKLTYKRGWERIPTNWYRRSVDYGLIDVNLDVISLITKYPELGSIGGNMGEVNSY
                     AGVDISDITGGVLNLTKLLEGNNLLCFVFEVVKTVSPNSLSGLFSIVVPPLKLITDALG
                     TALLDLSCPALKDLQVGGESFSKGIQKKFPGAKINASL"
ORIGIN
        1 gactattcct ttcgggaagt agatttaatc ttcgccgctc caccactcca tcctgctgct
       61 agaacctctc cgccacaact tccgtctata tcctcttcca gagtaaaaaa gcgtttctta
      121 gactggattt taccaagctg gtggagattc agtaagcaaa aggtaactca accagcagaa
      181 gggttctcgg ttcagagacc aagcagagtt ccacatacag tcaacagctc gacagttact
      241 taagctctta agcagggtag ctacactagg aggaggagta cttaatagat ttactagaga
      301 ttctaatata aaatactaca gtgacttctt aagcttatac agtactactg aaggtatatg
      361 cgtatatagt tgataagggc tagaataatt aaattctact tcgaaataat acattatctt
      421 aagaatcctt aacatagaat gttagatgct gtacttgcta aatcctatat aaacccctga
      481 ctaactagac tctgaatatt tcgctggatt gcattcttta agtattcctt cttctttaat
      541 ttacagccca gctgtatctt ttcatctcca agacagtatg cctgctgttc cagaatacta
      601 gccagtggcc acaagtagtg gtcctccctt cgtttgttca tagcatcttg aatagtcgtt
      661 acccacgacc gatggctaac aggtctcagg gtatatccaa gggtacgcag gacctcccag
      721 atatcacgtt cccgcaaact ttcgtcaatt atctccacat gcttccggtt tgacgcagtg
      781 gaaatctgac gaataatggt ctcggcaact agaggaagag ttgatacagg tactcgtgcc
      841 cttgttgtgc tttcgtcata tacacccagt tctaccactg atgcaacata ccgccagagg
      901 tagtcagacg ggttagccac acccgtctcc ggaccaccga taataaaccc gggcttgact
      961 attgacatgc cgagacccag ctgcaggtct tcgctttttg tagcacagtg ttcaaccaaa
     1021 gcttgggcca gcaacttcgt cttactgtag ccatcgcgag cattgactag ccattcatca
     1081 ctcgaatccc ctatcgcact ccctccagaa atatagacaa agcgttggac actactcgat
     1141 gacaatgcga attgcagaag tgtaacagtt gcatcaacgt taacggacca caggtcgctg
     1201 gcacattctg tccagtgtac tcgggcccca ttatggatca cagcctggac atgtcctcct
     1261 aagcgctcca tgaggtcttg atcaattccc aagtttggct gagaaaggtc accgagacag
     1321 acgtcaagtt tatcttcaaa gtcagagcgc caccatggca ggttgtgaaa acgcttccga
     1381 ccttctgata tgttgcaagc gcgaaccagg acaatgaccc ttcgccctgc tgtgagaagg
     1441 gtttttagga tttcttgtcc caaataccca gctccaccag tcaacaaggt actgagtttg
     1501 ccacctgacg atacgctcga ccgggttggg gccgttgtca tgctgacatc caaagaccgt
     1561 ttcaaaccat caagtgcgcc tttcaagtca ggttctggaa gtatgtactc cccttgcccc
     1621 tgatcctgtg cgcttcggac atgatttgca atcgaggttg gacgagcagt ctgctccata
     1681 aagcatgaga ccggaatgtt gactccccag agtcgctgca gagtcttcct gagagatata
     1741 gctttgatcg agtcgattcc agcttttctt agcggtgtat cctggaagga gatactggga
     1801 tctagtactt ggccctgtgg cagtcgcatc gtcgtaacct cccttgctat ctgccgtcct
     1861 atcacatcat cttctgggac aacaccatat gatgcgtctc caataaggcg cagttgtgca
     1921 atcaagtcgg caaccttatt gcggtccaac ttggctgaag gaagccgcgg gaagtggtca
     1981 atggtgaacc aaaaactggg taccatgtat tctggcacct tcgtgcggag aaagctttca
     2041 atcttgtgag tatcagcatt gcactgaact agatcattgc tctccgagcc atctcctagg
     2101 gaaacatatg gtttggtatg gagctcgaga actgcaacta attgattgtg atagtcgccc
     2161 atactgggga gttgaaccat acactgtcgg acaaatggat gattggagat gtgatgttcg
     2221 atttcgccca actcgatcct ccgccccagt attttaactt gcgagccaat gcgtgacaca
     2281 aagtccaagc tcccgtcagg attgtaccgt cctaagtctc ccgtccgata tagacgggac
     2341 gaatgatctg ggtcctccag cacatgatga agccagactg gtggctggat aaaggccctt
     2401 tccgtggctt ctgggtttcc caaatatcct ctagcgacag ttgggccttc aatgatgatc
     2461 tcccccactt ctccaattgg tagaagcttg tctggatcgt cggggttgac aatccagcag
     2521 acaccaccag ctggcatgcc aatgtgggaa gcgctccgat tctcatctgc agggctgctg
     2581 atggtggtga cgacgctgca ctcactgacc ccatacccag tcaatagcct caccgaacct
     2641 gcccatgagc tgatgttgga ctgcaaagtt ctctctccag ccaggacgac agtctccaac
     2701 gttgatatct catcgtggtc aatagatgtg ataaaagatg gagtcaaaac tgcccagttc
     2761 accgattgtg aattgataaa ctggaccagt ccgttgacac gttcatgctc tgaaggactg
     2821 cagattgttc cccccatgca caaggtagtc agaatctcga cgatacatgc gtcatgcgtg
     2881 tacgatgcaa attgtagtac tcgagaatgt cggtcaataa attgtgctgg agcatgacgc
     2941 gccattccgg aacaaaatga ttgatgctcg accacaaccg cctttggctt tccagtgcta
     3001 cctgacgtga agataagata agccgcatcg ttagggtgag atggccgtgt tgatggataa
     3061 ttgtcggtcg tctgaggcag cataaaatca tatgtggaaa tttcaatgat ctgatagtct
     3121 gaaaataaat gacggtgttt cgattcggta accacaattt tagcgttcac ttgctgcatt
     3181 ataacattga ttcgacttga cggtgccttg ggatccaatg caacaaatgc tccgccagcc
     3241 ttcaaaactg caagcatggc gactatcatc gatggcgact tatcgaagca tagcggaaca
     3301 attttctcgg ggcaaatgcc atgtcgcttg agatcagaag caattcgagt ggccatgcca
     3361 ttcagatcac cgtatgtaag agaggctact gttgaagcca ccgccacctt ggtaggttgc
     3421 gcggccgcct gagcctcaat ctcgtggtgg atgcacgtct gctttgtggg tggtagaggt
     3481 cggttccact cgaggaaatg cttccaatgg ctttcgggca cttgaatttc agacataatg
     3541 aaagtaattg atggcactaa tgttgctgcg taggcgtata ttccttttct acagaattaa
     3601 ctaagtcttc acatataaat acttaaggct caagagcatg acaacacacc acagcttgtg
     3661 cttaaatcta ccaattcaaa tgcgcgacac tgagagaatc acaccaggtc cacagctgtc
     3721 tctggattct tcatctacgg tcggatcagt gggtattcgt aagctgactg ggatctactg
     3781 atcacactac tcccttacac ctgcatggtc atgtccggcc ggggtattcg gaatggacgg
     3841 acggagagtt actacagtta ctgtacataa tgcggaccct tgtggacgcg aatagttaag
     3901 cgccttctta ttaaggttta acttaaagtt cccagtcatc ttgtgtcaga acgactcaac
     3961 cagttttcga cgtaacttta ccgcatggta agcaataccc ttgtcagcac agatgatgat
     4021 cggcgttagg tcgaggcgcg ggccgaccct gctgaactaa agcacagtac ctgtgtgatg
     4081 aatgccggta tcatcaagaa gtggaaatag aggatttggc gggactatta aaagggaaac
     4141 gctgttcata tactgctgaa aataaaatcg cttttctcag tggtcttaaa gaattcggga
     4201 attacttcca gagactttgt gtttccctta cccctgttac tatttcgccg agggcttatc
     4261 cttacacttg gcgaatcctt cctgtgccgc tgcatgttgg tctgacatgc tgcaacaact
     4321 aacatcatga tgggattttc atgtgcctta cgaagactcg ctgcagaact gtacgtattt
     4381 caacgagaca attaaattct ctctgcactt ttctcttcca cctgactacc gctgtgagta
     4441 ggaaatactc gtgttcattc attatggaat gtcactacag tgaggctcag gtacgtctgc
     4501 cgacggtgcg acacttcaat tgcgatacat ttacagcatt tgctgactcg ccttaacctc
     4561 agcttgctag tctgttactt ccatacttgg aaaggtttga tgaaaatgcc atcaatggtt
     4621 tggccagcga gctcaaatca catggaatct ctgtctatgc tgcagcaggg ttcgatccca
     4681 atgtcggctc cagtcttaca ttcaagaaag aagttccacc aagtgatact agtattttgg
     4741 aagatgtaga tcatgtcaat ctgtattctg aacaggacaa cttccactta tcaatgcttg
     4801 acatgatgga cttccataca ccagatatca tggacatcgg gctattcaca gatgttcagc
     4861 atgaaggcga tcctgttgat gaactagagt tgtcaagcga cactagatcc tctctctcgc
     4921 cctccagtca caataccacg acagggcatg agactggttt atcatcagtt acgccgcctc
     4981 aaaggtatgt gccaagttct atccctacag cttccttcac tcacgaatta tagttactgg
     5041 accagtgata acttggtatc tacccgagcc ctcccaacta ctggtgacaa acaactcagc
     5101 ccccaacgac ggaccgaaat cgcagacata tcgtcactgc ccacgtgcca acaaatcagc
     5161 cttgaacctc aatgtcactc cgtgatggag gcaccatgtc atggaaaaga agtgacaaaa
     5221 aggaacaaac ggtctaggac ggaagctcaa gaagcatcca atagtccatg cgcaagttca
     5281 acagctgatt cccagactaa cccagcccca ctacgcctgc ggtcagtatt tgggcctggc
     5341 accaagtaca atctgtcaca caaatcgctt catgagatat ctgacatttc agagaactgc
     5401 atcagaccag atttggtgga gttcctggag gagaggttga cccggtggaa gaagacaggg
     5461 ttctggcatc aagaccagat accggagccc accgccagtg gtgcagggcg cgaaaagctc
     5521 atcgatgcct attcttgcat atgcaggctt gagagtagaa tgaaagacga tcagattctc
     5581 aaccgggtgg ccgtggtgat gttacatacg gcctacgagc aggcctgcca ggagtggcga
     5641 catgctggta cgcatcaacg caaaggaaga ggacgcggcg atgcgacgac cgtgattgac
     5701 gagatcctca gcgaactaca tgaagattgg gacgttgggg atagaaagcg atatcatcgc
     5761 agtcgattcc acgataaaaa gcgatttgga aagcggtggc tcgtactcat taagtcgttg
     5821 ggagtcggga ttcttctctg tagctcacag cggctagcat cggcagtgta tgtacttccc
     5881 ttccaaataa ccctcttcat tctggatact aacctgagtg aatctgcagc cacacgacgc
     5941 tttttaccgg cgacatgttg caggcgctgg tttgctgtat ccaacagtct caggctaaac
     6001 agctgttaat acttgagctc ttgaacccaa ttgccacctt gctcgtccaa ggtggacgct
     6061 acgaaggcat tgacccagat aaaattatca gagaaattag agcacttgat tctttagagt
     6121 agggtagaat agagttgaga cagttacgct acccacatag ccaaactgcc aaaagccctc
     6181 ttcaaacagc attcaatgca tttgcaagca tctaatgata aatcagcaac catagggtag
     6241 aatctctacg gaccctgttt ggttggttga gatcaacgaa atgccagatt gaatcaacac
     6301 ccatgcaacc tcatgtcagc caaaaggttg ccccccacct gaagtacgta ttccccagca
     6361 tgtattcaac aacaaaaggg agttcttttc ttgatcaatt gaaagttgtt cagtaagcaa
     6421 tctgttggag atcatgaaat tgttttaatt aattgatgag ataaggttcg tctctcacgt
     6481 ctttcctgtc atcaacaatt gtacatcacc caaccgatgt agataagtac aagtcggggt
     6541 tataactcaa agtatagtac attatagaaa taaattcaaa tcttccaaac tattatttga
     6601 ttgcaatcaa tcactactac gacgaaaaaa tcacttcgca tacttacatg ttgttgctgg
     6661 atatcatgga cagtcactgc atccataccc ttgtggacca gagagcctcg tctcagccac
     6721 tggaaccagc cgttgagact tacgatgtat cactgtcata cggcgaactg tccgccatgt
     6781 cctcaaagct atctcaatac cttgtttcct tggggattta tccagaagca aaagtcgtcc
     6841 tgatgatgga accttgtgcc tcgtacgtgg tttccacaat ttctgtgctc aaggccggag
     6901 ccacatttgt gcctctggac gccacacagc ccacaaaacg cctcgctcaa ctaatcaaag
     6961 atatcaaacc atttatcatc attacatcca tcgaggttca agacaaagca agaagccttt
     7021 acgacaacgt tcttgtggtt gatcaaaccc cgagtccctg gcaagacgct ccgttaaaga
     7081 ctggggctgc ttgccatgtc aatggaagca acgcggcata catcatcttc acctcgggca
     7141 gtacaggctt gcccaaagga gtcatcatag agcatggggc attctcagct agtgctctgg
     7201 ctcgtggtaa tctcaccggc ttgtctttgg ggtcccgcgt gcttcagtat gcagcacaca
     7261 cattcgatgt ctcggttgat gagattctga caacgctgat ccatggagga tgtgtttgta
     7321 ttccatccaa agcggatcgg cttcttcttg agcctgcaat caaccgactc caagtgaacc
     7381 atgcactcct tacaccaaca tctgctaagg tcctagaccc cgatgccgtt ccaagtctta
     7441 agactttaca gctgggaggg gagctgttac ctgatgatct gattagaaag tggtgcagta
     7501 gggtgcggct ttttaatgtc tacgggccta ctgaggccag tgtcgcttgc ataatgtcgg
     7561 agaagagcca gaaaaacatt ttcggcaatg tcattggctt tccggtaggc agtgtctgtc
     7621 gaattgttga ccctgacgat cataaccaac tcgttgcacc tggcgtagtg ggcgagttac
     7681 ttattggtgg acggatattg gctcgtggtt atttgaacga taacatacgc accgcctctt
     7741 cctttatcga gtcgccgcct tggacgtctg acgacaatgc aacgaggttt tacaagactg
     7801 gagatctggc aaaaatagat cattatggaa gtgtcacgat cctcggccgc aaggacaacc
     7861 aggttaagat tcgcggacaa aggatcaacg tcgaggagat cgagactaca ctacttgcga
     7921 cccatttgat tcgcaactgt gtggttgaac ttccaaagaa agggccattg gcgaataagc
     7981 ttgtcgccat tgtcagcaca acttcggata cgcctcactg caagcatcct ccacctgcag
     8041 cattttctga acagctgcaa gcctctgtct ccacgttaga tgggcttctc agaaccagac
     8101 ttcacgatgc attgcaagat catctgacca gtgctatgat tccgaaaagg tggattcgaa
     8161 tgacttctct ccctgaaact acttcgggca aggtgaatcg gaaggaaatt cgaaggtggc
     8221 ttgagagaat ggacgcttcc gttctccaat cagtatctct ttcaaacgtt gagagcacag
     8281 gctcgaggca atcgacacgc cacaagattc agcccgaaca cgagaagata ctatgcagaa
     8341 tcctcggcgt taaccctacc cttctcaaac ctcatctgtc cttcattcag aacgggggag
     8401 actctatcgc cgcgatcgag ctttgtcgac tgggcaggga aattggaata tcattttgga
     8461 ttagcagtgt cctctccgac aacagcttag aaaagctgtt tcacacatcc aaatcccgct
     8521 tcaccaagac aatcgcccat gagtctcagc ccggaactcc ttttccctta tctccggtcc
     8581 aacgattctt cttcgacgtg gtgggaaatg aacacagttc cttcactcag tatgtcactc
     8641 tgcagctgaa aaacaggatt tctattgccc agctagaacg ggtgattgac cgtcttgttt
     8701 cagcgcaccc tatgctgaga gcccggtttc actctgagaa cgacacatgg ctccaatcta
     8761 ttcctgaacg catcagcggc tcctattcta tctttcatca ccacggcgta ggaccaccaa
     8821 atcatgaact catgcaacca ccggttctat ccctcgcatc ggaccctgtg ttgaatgttc
     8881 gcctgtggga ttttgacagt gggccgcaac agctacagct gatcgcccat catcttgtag
     8941 tcgacctggt gtcttggaga atcattctcg atgacttgag caaggcctta cgacatgaac
     9001 gtcttccttc ggcaggcatg tcctttcaat cgtggtgcgc tctacagaaa gagtacgcca
     9061 aaaccttgga tccgaaattg gtgctaccta tacctattat ctcagacaac tgcgcttact
     9121 ggtacccctc tgtagcccag caggagaaca aacatggtat gacggagacc tcaacctttt
     9181 ctttcgatat gttgactttt aattccctgc tggtcggctc gttgagcaag actcaaccta
     9241 ttgaactcat ggtaggatct ttctataccg cattcgccaa ggtcttctcg gatcgggaaa
     9301 caccaacagt ctttgttgaa tcgcatggaa gagagccctg gcagaccggg atcgacattc
     9361 tacagacagt gggctggttc actaccgcgt atccaatcca cgtcccagcc cagaaggcct
     9421 ctgatctcaa cgagtcaacc ttacatacca tgagggcgag acgctcgata ccagctaatg
     9481 gacaccaata ttggtgtcac aggttccttg agcaatatga gccggatgaa cgcaaaagat
     9541 cggcgccttt ggaattcgtt atcaattttg ccggtcaatt ccaacagctt agccaagcgg
     9601 acttgccttt ccgggtcatg tctactgtgg gtgaggagac cgctgagccg caagctagac
     9661 gcctctcgtt attcgacata ttcatttcag tggaaggaga ccaactgcat ttcaacatca
     9721 gctttccatc ttgggtctct catcgggaca aaatccatca cctgtccacg gtctggaagg
     9781 atgtactcga atcggcaggt gtctttagtg agcggccggt cttggatcca gaacctatcg
     9841 atatgctcag ggagctgtgg catgactgtt ctctaaagga tatagacgaa gtgtactggg
     9901 cctcagacgc acaaaaccac atgctgaaca gctcaagtcg ccatccttct ttttacacgg
     9961 ttgttggaag gtggcggttg aagtgcaata ctggagctcc attgacggat gcctttcggg
    10021 tgcaggatgc gtggaaacgc gtgatcacca atcaccgtgc tctgcgcact atattcatcc
    10081 ctggagaccg caaatgtgga tttctggctg tggttatgga acagtccttt cccatggtac
    10141 tcactggagg cgcatctgat acctctgata ctaacgggac gacgaggttc tttggcctgc
    10201 agtccaatga aagagcaatc catttgccac accgcattat cctccacgag tcaaacgatg
    10261 gcagcatact tttctcgctg gagatcagtc acacagttat agatgccacc tcacggtcca
    10321 tcctaatgaa tgaacttctc gatgcgttgg ttgacataga ccttgtcccc gatgatagcc
    10381 actatcacga atacatcgag agtcgggacg ctctctatgc gctttcacct ccctgccaac
    10441 caccaccatg catattcccc cctgacctcc attgttccga ttccgctggg tcacaactct
    10501 ccacccacgt tgtggagtta tcgcaaacat ccactgcaaa catgagtcaa atttgcagcc
    10561 aacatggaat tacaatgtcc agcttattgt tcttgtcctg gaccttggtt cttagcaact
    10621 atacttcgag cgatgacatt tctttcgcct acgtggcttc cggtcggtcc atggatgtcc
    10681 ctggtattga gcggtttgtc ggtctttatg tagatttact tatcctcaac atcgatacta
    10741 gtggatcaga ctgtctgttg gacttggcat tgagagttca acagatgtca gctggctcat
    10801 ccctccacca acacaaccaa attccggcgt gccggaatcc taagaacggg cgttttgatg
    10861 gacaggttaa cacaatggtc aacattcgaa acgttggcat cgatagtctg aggctagaac
    10921 gtcatgactt tgagttattg ttggacagtt ttgaagatcc ctgggatgta agatttttta
    10981 atacttcttg tcctttcctc ccgatttaat ccatcctatt ttaattttgc gtatactgac
    11041 ttaacatgac agtacgatct caccgtttct ttcgatataa ttcccaaagc tccgctccgc
    11101 tgttcaatct cctatcggga gtcgagtatc tcgtccaacc tcgccaacga tgtaggcgat
    11161 accctcgcga gatccattta cctgctgttg aacgatcccc ggatcacaaa agcagattgg
    11221 aaggcgcgta tagccgaatc ccactcctta gttacagaat agaggctaca gaatatattt
    11281 tggtagttgg aactgttagc tactcccatt gatgaacatt tcgtgtaatg acgctgggtt
    11341 tgagatcatt tccgggtatt tgacgtttcc cagattagtt atcattaaaa cacctttata
    11401 tataagtagc ctctcactca gtagtcactt agccgtcgca catatatcct ccatctatcc
    11461 aatatggatg accttatgac taatattgaa cattatcatg tttccctcac taccggcttc
    11521 ctgcctccat ctgcgccact tacccaccta cctcagaaat actacgaacc gtgggaaacg
    11581 cttgcatctt ccctccctac tcgaattcgt gatgggtcac tgagacacca ggcctcgttg
    11641 attcctctcc tggagactga ctttcttgtt accgatgcgg agtggcagag ggcttatgtt
    11701 gttctaggct tcttgtcgaa tgcttttatc ttctgccagt atcctccctc tgaggtaata
    11761 cctgaagctt ccacaacccc atttaacgct gtgaaaactg acaattttct gtagagacta
    11821 ccgttgagcc tagctgaacc catgatgaat gtttcctgct acctaggctt gccgtgcgtt
    11881 ccaacttatt ctggtcaaac cttgtggaat cactgttaca tttctgagat ccaactgcct
    11941 gtcttggagc aggttaatac cctggtttct ttcacggggt ctcgagaaga atcggcattc
    12001 tttggcatat ctgtagcaat tgagaaatgt ggttcaccgc tgattcgaac cttgctacac
    12061 gccatggcag ccgcggaagc tggaaatgag aaagaactca cagcatgcct gtccaaagct
    12121 atgatcacaa ttgactcgat aacatcgata ctgccgcagt tatacggcag gtgcagtcca
    12181 tcattcttct acaacacact aaggcctttc cttgaaggga cgcaagatct gaagtctgca
    12241 ggtctaccta atggtgtttt cttcgaaacc aaaaatggag gtagttacca gaagtttcgg
    12301 ggacctagta acgcacaaag ttcgctgttc tgcttcatcg atatcgcgct cggtattgag
    12361 cataacgata attcctttct tacggtgggt caacgaaaag ggcctacacc cgccattatt
    12421 tgcatcctta ctaagctttt gtaggaaatg cgtcaataca tgcccggccc tcatcgggat
    12481 ttcctcgcaa gggttgaggc gatcgacagt gtccgccact tcatctccgc taatccggat
    12541 gcgagtcaac tccaagaagc ttatgagggc tgtgtcctgg ccttggctcg atttagacag
    12601 atacatatcc gacttgtggc aagatacatt gtgataccct ccaatggtac taaaactgct
    12661 gatcagtctt caatgggtaa cggtctgtcc tctgaacctg tcagtatagc gggtgcccaa
    12721 ggcacggggg gtacaaagcc ggtggaattt ctcaaagtta tcaggaatga tgttctcgaa
    12781 tctcttcaag cttcatagta cttgcctggt ctgtaaatat tattgggctc atgatgtcgt
    12841 cagatttgcc cgtgttaatc ccatggcatt cagttcattg atgagtcgtc caccgattgc
    12901 ccgtccccgt tgtatatata gccacaacca ggtgacacgg caattacttc gagctcttct
    12961 cagacattaa caatggtatc ctcactcaac aatctaggtg ttcttctccc catcgagggg
    13021 gtaataattc tagtcttcgt cttatcatgt ttctctttgg ctatcaaacg gctctatttc
    13081 agccctcttg ccaaattccc tggccccaag ttggccgcat tgacaatgtg gtatgagttt
    13141 tactatgatg tcgtcaagcg agggaactac tttcggcaga ttgctaagat gcatgatcaa
    13201 tacggtaagt cagccttgat acgaaaacaa gacctgtttt cttaaataaa catatgtgct
    13261 gaaaactgac cataggtcct gtggtccgta taaacccttt cgaacttcat gtcaacgacc
    13321 ctacctttta tccaatcctc tacagcagtt caaccaagaa acgagacaaa tggtcctggg
    13381 cagcaggaat gtttggtaac aacacatcag ttttctcgac tgttccacat gaccatcatc
    13441 gaatcaggcg tgctgctctg aatccattgt tctcacgcac cgccatcaag cagctggaac
    13501 caaccatcaa atgccagatg catgagctaa gtcggaggtt agactctttc tgtgaatcag
    13561 gaatggtctt ggacctggga cttgcgttca cagtgtttgc agcagatgtt atatccgcat
    13621 actgctttgg cgagccgttc ggccttctcc aggatccaga ttttgcacca gagtgggttg
    13681 aaactgtggc agcgccttca gaactgggac acctgataaa acaattccca tgggctcttg
    13741 gactattcag gttgttgcca cgatctttaa tcggggttat tagccctgca attgtccgct
    13801 tatacactat acaagaggta agtcaactac agacaattaa atcaagcttc tgctaattca
    13861 gattcttggc agtggatgag cttgaatgtt caaagtctta tcagtaaacg ccatgatgac
    13921 cattcgagct cagccaagtc ttgtgtattt gaagcactcc ttcgcagtaa actaccggcc
    13981 tcagaaaaaa ccgttgaccg tctgaaaggc gaaggacaga ccctcatcgg tgcaggcacg
    14041 ctgaccacag ccaatgtcct aaagcatgta gtctttcaca cactcgacaa ccccgatcgc
    14101 ctccatgccc tcgccgctga attagaagct gaattcccag accccaatga agatgtctcg
    14161 ttagaccggc tggagagact gcctctcttg acggcctaca tcaaagaggc actgaggctc
    14221 ggctatggcg ttacgcatcg actgcaacta ctcgcagatg aaccactaca ttgcaacggt
    14281 atgattattc ctcctcggac ccccgttggt atgacatcta tttttatgca tgacgacccg
    14341 acggtctttc ccaatccgcg ggaatttgat ccagaccgat ggctgggcga ggtagaagat
    14401 cggaggcatt tagaaagatg tttcgtgcct ttcagcaaag gaacaagaat gtgtttggga
    14461 atgcacttgg cttgggcgga gatctacatt gtcatcgcga cggttttccg atcttactcg
    14521 tttcaactac acgacactga ccgcagccac atcgagatgg ctcatgactt ttttgatcca
    14581 gcgcctaagc ttgattcaaa agggttacgt gtcacggtac agaggaaata aggtggctgc
    14641 cagttagtgc agggtatact taaattgtac cagagtatgt ttctattacg actagcgaag
    14701 ctagattagt cctaactaga atgacactat tattctctgc ggattcgcat ttgctgtctt
    14761 aactacacca gacctagtag tacttacctt catgctacaa tttaaatttc ttagtacatg
    14821 catttatatg tatttcgtgc gctttggtca acgacgtgac gctgttacaa tgatgacaac
    14881 acttttacat ttaattacta gggctacgca tagtttctag gcttagtgca tgctactgag
    14941 cagataggct catcagcaag tttcgatgat aaaacctcta atccagaatg ccatttaggt
    15001 aagcaagcag tacttttatc tatatttatc cctcttagtt gagacaaatc ctcaactatc
    15061 ctcattgact ttacagtaca tctaacacta ccgcaaaagc ataatggaac tctccctgag
    15121 cttccccgta tcctggcttt gtgccctttt cactgcaatt gcactatatg ttcgtcccta
    15181 ttattgtccc tttaccgcct tgtcttgtta ctaacctacc attggtcagt gtattgcagt
    15241 cgctttttac cggttgttcc tccaccctct ggccaagttt ccgggtccgt tcttgtggaa
    15301 aatttccatc tggcctacgg tatggcaatg tgcccatgga aagcgccatc ttgatctcct
    15361 tgccgcccat aaacgccacg gtcctgttgt ccgcatcggg cccaacatgc tatcttacaa
    15421 cactggctca gcagcacgga ccatctatgc ctctcgacat gccaacgtca ggaaatccga
    15481 tttccactta acagtcgatg cttcggtctc ggcacctagc ctgtttagca ttgtggacag
    15541 ggaaaagcat gcgtttcgaa ggcgagtcgt ctcccaggcc ttcactgaga aggctatgat
    15601 ggacgcgagc gagttttact tgaaatatat gaaggttttc cttgatgtac tacacgacaa
    15661 ggttggtaca ggttggacca aagtcgacat acaagaacat gcaacttggt ggacttctga
    15721 taccatgggg gacctatctt tgggacgcag ctttaactgt cttactgaac cgacttttcg
    15781 acatgcaatc cccatgatga ggaacgggct gcgatacatt tactgggtat gcatagttat
    15841 aacagtgcct tgcgcaaaac ccactggact atgttatcat cgaatcgcta atgctattta
    15901 caggctgggc atcttccttt tagagatctc gtcgactaca tcttggcaca ccctatattg
    15961 tctcgatacg gtggccagtc cgcagtcgat aataggaact attttgactt ttgcgagaca
    16021 gccatccagg agcgtataaa ggaagaacaa gacgctttgg ccgctggggc ggatgaagag
    16081 agtcggcgca aggattatat ccactaccta ctcgcagctg tggatcccga gactggagaa
    16141 aagcttacca agaacgagtt agagtctgat gccagcctcc tactggcagc aggcggggat
    16201 gcaatgtcta atgcaattgc tggcatcatg ttctacctcg ctcgtcatga ctttgctcgg
    16261 gaccgagcaa cagcagaaat ccgtcaccaa tttgcttccg ctgaggatat tcgtcaagga
    16321 cctggattag ccgcttgcac ttaccttgaa gcttgtattc tagagtctat gcgaatggcg
    16381 ccaccagttg ctacgagtcc tctcgaacga gttacggtag gaaacggcat cgaggttgat
    16441 ggacactggt ttcctgcagg gataactttg ggggtctgct tctatgcatt gaactttaac
    16501 gaaaccatcc acaaagatcc gtaccgcttt cggccggagc gatggctgag tagcgaggaa
    16561 gggattactg ctgaggacgt ccagcagtct aagagcaact tctttccatt ttctgccggg
    16621 catcgacatt gccctgcgcg gaacctcgct agtcgcaacc tcaaggtgtt tatcgcaaat
    16681 atgctctggc acttcgatct tcgtccagcg acaagccttg gggttaatga gtccagcggt
    16741 gaagagggtc agacgggatt gttctgcatc gaagatgcac ttattagtat tgcagacgga
    16801 ccagttcttg agttcaaggc acgattaggc tataatgctt cgtcttctta ggagagtgtc
    16861 tcatgccata caaacggctg cattcaattc cagactattt aacttttgac catcacatat
    16921 tcgcaatggc atggttaaca taacagcaca ttgttcaatt caagactaac agctagtttt
    16981 aactaaatag agcttccttt gtcgcacatc tatcccttta gatcatcatg gtacacacct
    17041 gggttgatgt aggaggtgat agccagtgat ccatcacgtt gaaaagccac tgcaaggtac
    17101 gtctgcaggc gatgtccact tccctctggg tgtcccgcgc cgatactgcc caatgcacgc
    17161 atgaagccat cgtgaaactg atctcgctgc ctaagtctca gatattgacc aagtcccgaa
    17221 gccacagctt catctgacct tccaaaacga atgacaggta tgtagagttt cacatcagga
    17281 agctttgaac tgggggctat atcgaagtaa tatgtcattc gtccataaag gtcgaagtca
    17341 tgcgcaagcc ccttatcgaa gacactttga acgttgagtt catcgtcccg agagatcgga
    17401 gtttctttgc ccagggcaaa actaaggagt acctccagct ccttgattcc acgatccaca
    17461 tctgttattt tccctccaag tgtcatcact gacactatcg atgcgaagga agttgctgtg
    17521 gttgaaacgt atagtttcag acgagattta ttcggatcaa cacaatcaac tgccagcatg
    17581 tcagggacca gatctatccc catttcattg ttcttgacaa agtccagaga agcatccaga
    17641 gcagctgtat tgtttaacac cccacgagta gcgcttgcaa aggtctcaaa ggttggaggc
    17701 cctcctgatc ctgcttccgc cgccggaagg aagtaggctt tgacaacgac acccttctgc
    17761 acatgctcaa aagcgacgaa catatttgcc ttcggcgcgt caggattgtt tgaggccatc
    17821 tgtcgctggt ctataccaaa cgctttgacg aagtggtgga accaagtgag atccaaacca
    17881 ggaacgcaag aggctagatc ttgggtcaga agcttctctg tttccagata attgtacgga
    17941 tcagtcgaac tgccagtatg ggatccgatg gcttcgatgc agtaacgaat atcaggagag
    18001 ctggtggagt tattccactt ccagctgtac tcgaacggag tcccgtcgtc ggtaagtaga
    18061 ctggtatagc gagagggcga gttgaacttt tcacccttgt tcaatgggcc aaccctggga
    18121 agcaccttcg cataaagaaa cagaaggatt tcaaattgtt tctcgatggg atatcgcgcc
    18181 tcctgcgcaa gtagacagag ctgagagcca atcagcttcc accaaggtgc tgattgcgct
    18241 cctgggtcga cccactgaga tgctatggac cacgcagatg gaccagatgg gcattctttg
    18301 gaggtagtgt cgttcatgtt gataatgaca gttatgatgt gttatgcgat gctgttgtgt
    18361 aatgtaggtg gactctacct gattgtcacg gcgacggtga atatatttat gtccacgtga
    18421 agaacagctc aactcggtaa attggggata gactgtcatg gaaatataca tgatgactta
    18481 tcaatctggt tgcttatata tcctccaatt atcaattcaa tgtaaatgag attccatgtg
    18541 ccaagcaact acaatacttc cgcaatggaa cagcacttcg aacatttgag ctgcatcccg
    18601 tatcttgaga acacagaggc gtcgagatat cagacccttg atatctggat accaaccagg
    18661 catcaacacg gagactcaac ccatgggtat tggatcatgt aaggacattg ttcaaattca
    18721 attattctag ggctgtggcg ttgatatact ttacagtttc atccacggtg gcgcctggcg
    18781 cgaccctgac atcaatgcga ccaactttgc tgaaaaggca gtcttggatc taatcacatc
    18841 cggtgtctcc cagattatcg aaggtatagc ctctatcaac taccggcttt cgcctcggac
    18901 acccagtcaa ccagtgccat ccggaggcca tgtcggcggc gaacagcagg ctatgcatcc
    18961 agatcacttg aacgatgtca tttcgggtat agaatacttg caacgtaaat tccgttttgg
    19021 aaaccgatat atattgactg ggcattcttg tggcgcaact cttgcgtacc agacattgat
    19081 tcggcagacc atggataaga cagaaaccca cgctgcgcct catgccatca tcggtgtcgc
    19141 gggtctgtac gatcttccgt tgctacgaga tatggatcct atgccaccaa tgtgccatca
    19201 atttttactt gctgcattcg gcagcgatga gacgttatgg cgggatgtaa gtcctgctac
    19261 atacggtgac ttcgaaaggc tttggccaac agggaagctg gctgtcttgg tctactgcga
    19321 agacgatgag tatgtatcgc cggctcagct taatacgatg tatcacgcgc ttgagatttg
    19381 gggagagaag gaaggaagat tggttaagac actaaagctc ccaggcgggc atgatgaagt
    19441 ttggaggacc ggttctggac ttgcgagctg tgttgagaag tctataaatt atctacagga
    19501 tctgtctgta tctgaagcat gagatagaag agactctgtc cattcccaca gcctcagagc
    19561 tatagtcatg tcattcgcat gttgcgctgg ctcggaagcg tggcaatcct ccaagtactc
    19621 tccaagatgg cctagaaaac gttagatggt gattagatac cagacacatc ttgtatttgt
    19681 tttcaatctc actcacctgt agccaatggg cccagtgctg caaacaatat tgtggcggca
    19741 ccttgactgg gacttttggt tgggagagat ttcagaatca cggcaacctc atctgaaggc
    19801 atatgccgcc atagattggt ggctatcact gcaggtaacg ttagcaatgg cacaaaacgt
    19861 agaggatcgt cgggttccat ttaccacccg gattgacgga gaatgctgtg attccgtctc
    19921 tgagaacgcc agatgatatg gccttggcat gtaaaatgac ggcagtcttg gactgcgcat
    19981 atgccacgag aggcgagtag ctagtctccc agggaatgcc aaacgccttg catgcttcac
    20041 gggagggctc ttcgtcagga agtagatccg atgatccgat gaagtgcggg tcgccaaaac
    20101 ggaagggtga aacagtatga gcgctgctcg atacattgat cacacgccct tgaacgggtg
    20161 aagaatctgt cgaactcatc tgctcggcaa gtaacttggt gagtaagaag tgcccgacgt
    20221 agttaatagc caggtgagcc tcgataccct tctcagtcaa cgtgcgatct ggaatgcaca
    20281 tgactccggc gttgttcaca agtacatgaa cgcgagaggc aaccttctta atttcctgcg
    20341 cagcattctc cactgacttg ggcagagcaa ggtccatctg tatgactgag atttggagat
    20401 ctggatattg agcgatgaga gctttggcaa cttcttgggg acgctgaatg tcacgaccgg
    20461 tgatgatgag atggccgggg ccatacgggg cgagagcttc acatacggct gcaccgaggc
    20521 caccaaagct aacacccgtg ataacgacta catacgcaat caataagtat gcgcgtgttc
    20581 tgaagaggtc tgaagaagtg cttacaggtc ttgccagaga tttcaccttg gaatgccgcg
    20641 gcaacgtctt gagcttgggt agtgccatca aacattttta tagacgtggt tttgatgaaa
    20701 agccgaaaga attgcccttc ttgttaaaga aaagagttat ccaggtaaat tggtcgctag
    20761 gacgtttaga accttcggtt gattgaggga ttgttggaag tatcaggtgg gtttatatga
    20821 gtatctagcc cgagagtatt cttatacgag cgtctgaaat tcttcatgtc taacaaatgt
    20881 ccttggcatg cagtgcacat catgttattc ctggattggt gacccacttc cggggaattc
    20941 gttgatgaat atcaacgaaa ccccgcttcc cgcgcgtccc gtatttggct gacaccttcc
    21001 aaatgaggac cccatgtgcg tgcttggata acattacatt ttcacaaaac ttccgggctc
    21061 tggccgtgtc ttctgtactt ttacgcgatc tactgacacg atctatttga gaagaatatg
    21121 ccacccatta ttcactgcgt gcgccatggg cagggcgttc acaacctcag ctatgcaaac
    21181 catgatctgc ctgatcccga actgacccct cttggagagg aacaggcccg ggctctgacc
    21241 accaggttcc ctgacttggc caatgttgaa ctgatcgtat cgtcaccact acgacgtact
    21301 atccggactg ctctgttggc attcccgtta aagcttgaag gtggcatgca ggttctggcc
    21361 ttgccagagg tgcaggaggc gagtgaactg atatgtgata ctggcagccc tcttcctgat
    21421 atcaaagcca ttttcgatgg tctacccgtg gatttcagcc ttgtggagcc ggactggtac
    21481 gtcaaggtat gtgctctcat ctctccacat cccgttcgac tctaatcagg ttttggaata
    21541 aagcagggaa aatgggctcc gatcgcagct tctctcttag agagggctaa actcgcgcga
    21601 caatggttga gtgaaagacc tgaagctgaa atcgtagtga tttcgcatgg ttgtttcctg
    21661 cactttctga cggatgactg ggtcaatgct gttaatcctc aaggtgggtt ttatcatcac
    21721 tgcaaataca agtaccgatg ctgatgagtg acgtagcaac tgattgggct aacgccgagg
    21781 ttcgatcttt taccttggct tccgatatga gtggaggttg ttctcttgat gagactgaag
    21841 gatctagagt gagacgagga tgtgagcaac ctgctttaac aaaggagcaa cagctagagc
    21901 tacgggacaa agtactcaag acgtggattg aatggggggt aataaaaggg tagtagagag
    21961 tccaagagta ggagggtatc tttgttataa atatactaga caccagacac tataaattaa
    22021 agactagcat taatcttggc accaggaaac ttcttctgga ttcccttgga aaagctctcc
    22081 ccgcctactt gaagatcctt caaggcaggg catgacagat ccaagagagc agtaccaaga
    22141 gcatctgtaa taagcttcag gggagggacg acgatggaga atagaccaga aagagagtta
    22201 gggctgactg tcttgacaac ctcaaaaacg aagcacaata gattgttgcc ctcgagtagc
    22261 ttagtgaggt tcaaaactcc accagtgata tcgctgatgt caacgccggc atagctgttg
    22321 acttctccca tgttaccgcc gatactattg ctgttagtag atgtcttttg tggaacttgt
    22381 agtaaacgta ccttccgagc tctgggtatt tagtaatcag agagatgacg tccaagttca
    22441 cgtcaatcaa gccgtagtcg acagatcgac gataccagtt cgttgggatc ctttcccatc
    22501 ctcgcttgta agtcagctta tcgccttcct tctggacagc gaagaagctt ctcaatgttg
    22561 cttggtctaa gaataattag tatctctgcc ttgtgtataa aagtggcaag cttacccatg
    22621 atatcttcgt ggcttccctt tgtatggtta gaaagcatac ggcacgcaaa gaagtatcca
    22681 gcgttgcgaa caatcattcc agtgaaaggt ccatagtaga agtcggggtt ggtctcgatg
    22741 gtctcgtgga agcgaatctt ggcgcgttcg gcgaatgtgt cgaagtcata ggtgccttca
    22801 tcagatgcca tgtcgtagaa agactcgaac tgatccatcg ccatggtaga ggcatcaccg
    22861 gtgacataaa ggtcggccct ggtgttggac gaatcgccct cgatgatgtt gtgggaccca
    22921 acaagacctc tgggctttcc caatagtcca acaagattac ccaagatatt atcgtttccc
    22981 ttgggggtgc ttccaattga gaagccaggg ttgagcgaca gagggttgcc aacaaagact
    23041 acgcccatgg ttgtgaggat ggtagcgaga tcgataccca ttccatagac cttgttgatg
    23101 gcgccaatcg tctctaccaa gtttgtgacg ccattgcgtt tgatgtaacc atggttcgct
    23161 aacgcgttaa gtccggggca gggcccgcgc tggtcgccct tctcgaagtt cgggggtata
    23221 aactcgtgtt tgccggttac atcgatcggt tcgttgcctg cgtcgaacaa cagtctcttc
    23281 tcgtgggctg agcggactgc ttcatcgact acgctcgaca gcctggaagc agtaagatgt
    23341 ccaacggcac catgaagatg agagggaaat gcataaacct cgtcagctac gcaagcgacg
    23401 accgacaaaa ggtgaagcca cttcatggtt caattgataa aagagtgtat gtaaaggagt
    23461 gtgaggccgt aatggtggaa gagtaatgtt tcaagcctga ctggtcgagg gatgggaaac
    23521 agaacatctt tgtttggctg ttcattcggc cttgctcatt ggggatggct tggctcctga
    23581 atgtgaaaat ggcgatctgc tttacctggg cgggtcccaa tctaactaag gtagtactgt
    23641 tggtactgta cctgcgccgg cttgcctggt cggcatgtcg tggactgaag aagctgcctg
    23701 ccggcaaatt ttagcttgaa acgttgcgtg gttcttcagc cctgctagac ccaacgacta
    23761 gtctactagt ctcaacctgg atctacatta gtgacattgg ggtaaaatat gactcgttgt
    23821 gatgatatgt tctacggaaa gtttggcaag taagaagaca aagaacacag cataatacat
    23881 ctcgaaatgg tgttgg
//
