BGC0002256: fusarochromanone biosynthetic gene cluster from Fusarium equiseti
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Location: 1 - 23,896 nt. (total: 23,896 nt).
This entry is originally from NCBI GenBank BK013344.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002256
Short description fusarochromanone biosynthetic gene cluster from Fusarium equiseti
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
  • other (other)
Loci
BK013344.1
1 - 23896
via
Compounds
  • fusarochromanone
  • desacetylfusarochromene
  • fusarochromene
  • 4-hydroxykynurenine
Species Fusarium equiseti [taxonomy]
References
Chemical products information
fusarochromanone Evidence:
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Chemical database entries
NPAtlas
PubCHEM
desacetylfusarochromene Evidence:
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fusarochromene Evidence:
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Chemical database entries
NPAtlas
4-hydroxykynurenine Evidence:
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List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • DAD54574.1
  • fscA
 465 - 3536 (-) NRPS-like oxidoreductase
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    • DAD54575.1
    • fscB
    		 4464 - 6009 (+) putative TF
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      • DAD54576.1
      • fscC
      		 6648 - 11009 (+) NRPS-like tryptophan epimerase
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        • DAD54577.1
        • fscD
        		 11464 - 12798 (+) tryptophan 2,3-dioxygenase
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          • DAD54578.1
          • fscE
          		 12973 - 14631 (+) putative tryptophan 6-hydroxylase
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            • DAD54579.1
            • fscF
            		 15104 - 16851 (+) FscF
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              • DAD54580.1
              • fscG
              		 17010 - 18317 (-) DMATS-type prenyltransferase
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                • DAD54581.1
                • fscH
                		 18565 - 19522 (+) kynurenine formamidase-like hydrolase
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                  • DAD54582.1
                  • fscI
                  		 19841 - 20675 (-) oxidoreductase
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                    • DAD54583.1
                    • fscJ
                    		 22017 - 23426 (-) putative aromatic peroxidase
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                      Biosynthesis information

                      Biosynthetic modules

                      Name
                      Unk01
                      Type
                      nrps-type1
                      Genes
                      fscC
                      Substrates
                      tryptophan (evidence: Structure-based inference [2])
                      Integrated Monomers
                      Domains
                      adenylation
                      Name
                      Unk02
                      Type
                      nrps-type1
                      Genes
                      fscC
                      Substrates
                      4-hydroxy-D-kynurenine (evidence: Structure-based inference [2])
                      Integrated Monomers
                      Domains
                      adenylation
                      Annotation changelog

                      Entry version: 2

                      Date
                      Changes
                      Submitters
                      Reviewers
                      2022-10-07
                      Changed chemical structures for compounds: fusarochromene.
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      2022-10-07
                      Added NPAtlas links to compounds: fusarochromene.
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                      Entry version: 1

                      Date
                      Changes
                      Submitters
                      Reviewers
                      2022-09-15
                      Entry added
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      2022-09-15
                      Added NRP substrate specificities
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      Detailed domain annotation
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