LOCUS       BGC0002258             25000 bp    DNA     linear   PLN 17-JUN-2020
DEFINITION  Aspergillus stellatus GF10 DNA, shimalactone biosynthetic gene
            cluster.
ACCESSION   BGC0002258
VERSION     BGC0002258
KEYWORDS    .
SOURCE      Aspergillus stellatus (Emericella variecolor)
  ORGANISM  Aspergillus stellatus
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 17:13:06
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..25000
                     /db_xref="taxon:1549217"
                     /mol_type="genomic DNA"
                     /note="synonym: Emericella variecolor"
                     /organism="Aspergillus stellatus"
                     /strain="GF10"
     protocluster    1..25000
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[14990:22675]"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      14991..22675
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     cand_cluster    1..25000
                     /SMILES="C([*])C(-O)(C)"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..25000
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0002258"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..25000
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(214..1095)
                     /gene="shmG"
     CDS             complement(214..1095)
                     /codon_start=1
                     /gene="shmG"
                     /product="integral membrane protein"
                     /protein_id="BBI47413.1"
                     /transl_table=11
                     /translation="MLSDSPNQPLSEPLQYAFTAFAALTVYNSVELIVLTLATFKRYQG
                     LYFWSLLVSSCSLITNTLGFALFFFAPISNYICVTIILVGWYCMVTGHSLVLWSRLHLV
                     LQSPKVLRGILYLIITDAVLLHIPVTVLLYGAVSPNPDIESRFVVGYNVIERIQLIMFC
                     LQESLLSAIYIWETAKLLRLRPQRAHSVILVQLIAINIIILILDVIVVVFQYTGLFALQ
                     VVFKPVAYSIKLRLEYAILGRLVLVASGSEGGSSARVFSDEVQWPSVPSCEDEECQFRN
                     SSPRAGNGSGGS"
     gene            complement(2402..5014)
                     /gene="shmF"
     CDS             complement(2402..5014)
                     /codon_start=1
                     /gene="shmF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103:FAD dependent oxidoreductase (Score: 161.4;
                     E-value: 6.2e-49)"
                     /gene_kind="biosynthetic-additional"
                     /product="oxidoreductase"
                     /protein_id="BBI47414.1"
                     /sec_met_domain="DAO (E-value: 6e-46, bitscore: 146.4,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPPSASSSPSRPASQNITIIGAGIVGTNLADELLSSGWPASAITV
                     IEQGPLSLSGGSTSHAPGLVFQTSPSKTMTKFASYTVQKLLSVEKDGQGCFNQLGGLEV
                     ATTPERVEELRRRHGWATSWGVDARLISKEECLALYPHLNRDVVLAGLHIPSDGLALAA
                     RATQILIERTSAKGVTYLPHTRVTGITQENGRVTGVETSAGPIHSDTVISCAGFWGVEI
                     GALAGVDIPLLPLAHQYAKTGPVAALANRDVNSRMNGLNASLPILRHQDQDLYYREHGD
                     RYGIGYYGHKPMPVVAGELGPTPRQVDEKNMPSRLDFTEMDFAPAWKETKKLLPALAGT
                     ELDDGFNGIFSFTPDGGPLLGESPNLDGFFVAEAVWVTHSAGVARAMAQILTKGWSDID
                     VSECELSRFENVQLNRDYVAETSQQNFVEIYDILHPLQPRSSPRGLRTSPFYHRQVELG
                     AVFFETGGWERPFWYESNKSLLQSLPSEWRPVERDTWSNRFYSPITAVEAWKTRNAVAL
                     YDMSSFHRFLVSGPGATALLQTLTTSEVDVKPGTIVYTLLLNENAGIRSDIFVTRLDRN
                     TYQIGANTATDLAYLSRQARHLSTSSSTSTSTSSVQVTVTDITGATCSLALWGPRARSV
                     LTSARVSASTTSNTNLPYMHALPTTIASIPTLLLRKSYVGEYGWEIQTSAEHGRRLWDA
                     LYAAGKPHGLVPAGRAALNALRIEKGYRTYGADIGTEYDPYEAGLGFAIDGGKKDHFVG
                     KGALEGRNKQPLTRRLRCLTIDDGKSMVMGKEPVFINKKPVGYVTTAAFGFSVRRPVVY
                     AWLPGGVGEGAGVEIEYFGKRVRATVVPEPVFDPDGKRLLSDGEETDGDVGGKIRAVL"
     gene            complement(6271..8294)
                     /gene="shmE"
     CDS             complement(join(6271..6777,6825..7738,7787..8294))
                     /codon_start=1
                     /gene="shmE"
                     /product="transcrition factor"
                     /protein_id="BBI47415.1"
                     /transl_table=11
                     /translation="MPQKDRLAELEEKVNQILRGAAQSNHHEQQHQQQQQQVIEDAPDF
                     PTTGSHGDVNYTQDNAFFSIFGLDDGSPQASSLTVTKAIDLYLECCHRQPVWCFNIKEL
                     ANIESHPEELICSILALTSRFSREAEQGHRYADSAKSLIMLRIANGTVELATIESLCLL
                     AYSSFIDGQLQLGRFYLGLGLQLCRAAMLDTEAAYVREDRQAEQKKRLFWSLQILEQSY
                     GRQTGLLSIPTATWRPPYLSSGGPMEQEKNSIPNPPPPPRDTVGCSSPDDTGIWSMSIY
                     FGWVWSKVRAYVSHCASNRLTEPWRHESMYSVVLSDLTEIENSTPLCHRYEHVQFYRRT
                     AEELAVNRAYWVPWVKLQFMYHATLTVLNHPFLYIIASQYNPNLAIPNSFWRRSSELVL
                     LHATWIVRLIDMVSEKKLRLADPFFGHVAAIAASVQLYYCCADDPRLKYKSRADLAKCS
                     DFLRSFVPLSRACEGLSRKLDELTRIASGSDILDLDDWVPSKIRLNIPLMWDILQYNVT
                     DESGRETLLHPSLTPAFISTPANEASTTVDIIVTASPEVSVNTTDGGQAVPMPLYRSPT
                     AATAESLRNTSLRDPLVAPVDSLMLNTPWLWADSTQFGNMDDVEYHNSAPVVGDIEGSA
                     WWNLGNL"
     gene            complement(9023..10297)
                     /gene="shmD"
     CDS             complement(9023..10297)
                     /codon_start=1
                     /gene="shmD"
                     /product="iron-sulfur protein"
                     /protein_id="BBI47416.1"
                     /transl_table=11
                     /translation="MSSLWNYLGVGSSAAKPADDKNAVRALPSSWYTSQEMFELERRAI
                     FSRKWLLTTHKLRLPNAGDWLRYEVSGFQFILVKDRQGEINAFHNVCRHRAFPVVTEEG
                     GTARIFACRYHGWSYGLNGKLAKAPGYQDLAGFDKSKNGLLPIHVHIDNNGFIWVNMDA
                     SPEPEISWEQDFGGIDMQPRFQGINWDEYAFDHTWEMEGPYNWKILADNYNECYHCATT
                     HPDIPSIADLNTYSVDTKDAGIIHDAHSKPEQIAAGLKVAATYYFPNASMTVSPHFILM
                     QRFVPLEPAKSIMKYEVFRNKNSSDEDFNMIDSIYKRVMSEDKDLCAQAQKNLNTGVFV
                     NGELHPTMEKGPLYFQKVVRDLVTEHFEKEQMEKQEIWPARQRVPKEATASAKDEQFCA
                     SLSCNPEGGECCSSIGAQRPAAIAW"
     gene            11482..13333
                     /gene="shmC"
     CDS             join(11482..12002,12142..13333)
                     /codon_start=1
                     /gene="shmC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038:phenylalanine-specific permease (Score: 319.8;
                     E-value: 3.8e-97)"
                     /gene_kind="biosynthetic-additional"
                     /product="transporter"
                     /protein_id="BBI47417.1"
                     /transl_table=11
                     /translation="MSPPQDTDIQGKEPEKTTKDNNAAPSLLADMPGSVAEHGTEHNGL
                     HRQLENRQIQLIAIGGSIGTALFVSIGEGLSQGGPGSLLIAYSIYCVMLSLVNNCIAEM
                     TIYMPLSGSFIRLAGKWVDEAFGFMAGWNFYFYEALLVPFEITALNLVLSFWRDDIPIA
                     AVSVACIVLYALLNILAVKAYGESEFWLSSGKVVLILILFFFTFVTMVGGNPQSDTYGF
                     RYWNDPGSFATHSSSGSLGRFEGFLAALWSACFTCVGPEYVSVVAAEAKFPRTYIKTAF
                     KTVYYRFIVFFIGGALCSGIVVAYNDPTLVQAVTGEGSGTAAASPYVIAMRNLEIQALP
                     HLINALLVTTIFSAGNTYTYCATRTLYGLALDGRAPRIFTKCTKQGVPIYCFAVTMLIA
                     CLSFLQLSSNSSQVLSWLINLTTAAGIIDYIVMCVTYIWFYRACIAQGFDRSTLPYTGY
                     FQPWCGYIGLVWMVLVVTCYGYESFTPWDVTSFFTHYTMIIVGAVLYTGWKLLKKTRLL
                     RPHELDLYWEAPQITAYEEALSLREPVTTFWGEVFSFLRRDKGRNVPGEAVSA"
     gene            complement(14991..22675)
                     /gene="shmA"
     CDS             complement(join(14991..15999,16053..22675))
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (5-445). E-value:
                     1.9e-161. Score: 529.6. Matches aSDomain:
                     nrpspksdomains_shmA_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (581-900). E-value: 4.6e-85.
                     Score: 277.4. Matches aSDomain:
                     nrpspksdomains_shmA_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (975-1150). E-value: 6.9e-26.
                     Score: 83.4. Matches aSDomain:
                     nrpspksdomains_shmA_PKS_DH.1"
                     /NRPS_PKS="Domain: cMT (1420-1629). E-value: 2.8e-75.
                     Score: 244.9. Matches aSDomain: nrpspksdomains_shmA_cMT.1"
                     /NRPS_PKS="Domain: PKS_KR (2151-2327). E-value: 4.7e-40.
                     Score: 129.3. Matches aSDomain:
                     nrpspksdomains_shmA_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (2441-2517). E-value: 1.6e-12.
                     Score: 39.5. Matches aSDomain:
                     nrpspksdomains_shmA_PKS_PP.1"
                     /codon_start=1
                     /gene="shmA"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     itr_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 183.9; E-value:
                     8.3e-56)"
                     /gene_kind="biosynthetic"
                     /product="polyketide synthase"
                     /protein_id="BBI47418.1"
                     /sec_met_domain="itr_KS (E-value: 9.6e-165, bitscore:
                     537.3, seeds: 96, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 5.7e-86, bitscore: 277.4,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 4.4e-37, bitscore:
                     116.7, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2e-09, bitscore:
                     26.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAEPIAIIGTSCRFPGQSTTPSRLWDLLKEPRDVASVPPASRWD
                     ASSFYHEDPTYPGTLNAKEGYFLTEDPRYFDAAFFNISSTEAASIDPQQRQLLETVFES
                     LEAAGQRIDQLKGSSTGVFCGQMGTDWPDFFATDHQSVPSHAATGSARSILANRVSYFF
                     DWHGPSLVVDTACSSSMVALQQAVVALQQHECPVAIAAGTNLILSPSFYIVITKMTMSS
                     PDGRGRMWDAGANGYARGEGIASVVLKRLSDAVADNDPIECVIRAIGVNQDGHTQGLTI
                     PSGTAQLDLINSTYARAGLDPRTPRDRCQFFEAHGTGTVVGDPQEAFAIHQAFFGETPQ
                     TDEQHKVDDTEILHVGSIKTIVGHTEGMAGLAGIIKASLSIQNKMITPNALFESLNPAL
                     KAYTRHLRIPTEAIPWPSLPEGVPRRVSVNSFGFGGTNAHAILESYEPKKLLNGASNAA
                     SNGVSNGVSNGVTNGVTNGVNGHTRATSMLLPFTFSAASGKSLVAVLESYEQYLRENPA
                     VFPMDLAATLLCRKSALRYRLVLSATDNAALLAKVTGALQAARRNEALPCVTERNLGGQ
                     KRIVGVFTGQGAQWAQMGYDLISSSDKAMEWMGELQHSLDTLSNIHRPHFSLLEELESS
                     SADLQKAHLSQPLCTALQIVLVRFLASLGIQFSEVIGHSSGEIAAAYAAGFLTARDAIR
                     IAYLRGLVAAQACSETHQPGAMLAAGLSPEEAAEVCRSDEFKGRVALAASNAPASVTFS
                     GDADAVSQLEQQLKEKKTFARLLRVDTAYHSHHMLACTAPYRKALKNCHIEVQIPQTAT
                     EWYSSVYPGVKITLPDHAISLGCEYWIENMVSRVSFCEAVQGVVSEGYSPDVMIEVGPH
                     PALKGPVQQTLSSVVSGEMEMPYLGLLSRGGNGVETMALAIGSLWGYLGPSAVDVASYI
                     RQFDPSFRPKPINGLPSYPFLHEKPTDCFKRPVKQHLLRRGAPNLLLGSLEPNAGEDEL
                     RWHNYLKHDILPWLSDHRVLSRAVFPATGYIAMALEAAGILASKRSTAMRLVKIQDFVI
                     SQAITLPEDDPVGVETLFRLSGIQEHKSSHTTTARFDIDACTGETLQNRASGQLTILWG
                     ETDSDILAPKPPTPPGMHTLRTEDFYSFLAEVGYEYLGAFRGLQSIARQKDRSMAELSN
                     SIAIEEDGGKLSPLFHPVVLDTTLQVLLAALGAPDDGEIYTLLVPVRIKSVLINPAFCG
                     RAGVRAAGTVLSATGATAKLDADGISGDCDLFTEQGHGLVQMQGVDIAPLSQPLQERRL
                     FSKLVKGPAFPSMSWNLPPRSKEVSDYFESLERIVLLYVKFAYEQLTPEDRQGLDWHRS
                     TVVAWMERVLSLTREGKHPILRPEWLDHTRDELETFLQPMSHLAEARMSAVVFANVVPF
                     LRGEKLLLEEVRKDDVLTRFYEEDTGMRMMNDVLGELCSQITFRYPRMKILEIGAGTGS
                     ATRAVLSRIGHRCHSYTFTDISVAFFEDAKANLEEYEDQMFYKAMDIDRDPIPQGFEEH
                     SYDLIIASNVLHATKFMKETMTSVRRLLKPGGYLAIQEVTNLDTISTSWSVCGFDGWWA
                     GHEDGRKWGPMLSRDSWDELLKETGFGGIDIYTTPGDDEKVCSTSVIISQAVDDRLRLL
                     REPMNSCAESLLLPSQPTDLVILGGMLDSIKPLVSGLFSLVEPRFTRVIHAPSLDSAEL
                     AGLSDTNGLAILSFIDLEGSWLTDLTEDRLRFMQHLVARAKCMLWVTMGTETEYPHYGL
                     SKGWLKSLVQENPKSLYQYLNIADRKDASAPLLATTLMRLVYTDIPNDFMLPTHVHSTE
                     LELSYSDGILQITRLLDDPDGNDRYTAVRTRVTKDVDLYKTNVRVLPSSGRQHVIRMST
                     HKERPTLGNEFVSLRPRYSTLDPLPAENAIALHLVLGVDANTGSRLLAISSEHGYSMQV
                     PREWTWDVPTCVSTEQEAAFLSRAAEIIMATFVADLADTNSSLLVLGSGYSMRKAITRA
                     AAERNVAPFFISTHASAVGEGVHGVPAGASAQFLKRTLPRDVSVAVRLGPEGDYGLLAS
                     HTELALPGIQCLVPQKTVQQLRPIRNANTLSFGEQLIARLKQSASCIIDNAANGSTLEM
                     IACRDLSTQRAAFGALVDWTQCSTVPTQIEPAISLVNLSKDKTYLLAGLTGDFGQSLSE
                     WMVSKGARYIVLASRTPKVDARWIEIMAQRGAYIVPISMDLTDRSSVLNAYSQIQANLP
                     PIGGIVNGALILEDSEFLQTTAETIKRNLGPKVDGTLLLDELSGRNVDLQFFILFGSLT
                     GIGGNWSQSAYSAATCFQASLIHNRRSRGLVGSIIHLGVVSGMGIIARMGTDMINHVRA
                     TTGSYLLSERDVDRMFAEAILAGDPASGRNPEIINGVEPYRTDGTNNGEDLARFQKPIL
                     WDYVDYRANANKDHVGGLGKAASSVRAQLKSATTREEVAAIIDAAIKNKVRSKFSLADD
                     YPLSSATYLRDLGMDSLVAVDLRRWFFKELGVEIPLMDFLNGGSITELTGQVVDGLSDT
                     SVPNGGDGEKMANGVNGVKH"
     aSDomain        complement(15072..15299)
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_shmA_PKS_PP.1"
                     /evalue="1.60E-12"
                     /label="shmA_PKS_PP.1"
                     /locus_tag="shmA"
                     /protein_end="2517"
                     /protein_start="2441"
                     /score="39.5"
                     /tool="antismash"
                     /translation="EVAAIIDAAIKNKVRSKFSLADDYPLSSATYLRDLGMDSLVAVDL
                     RRWFFKELGVEIPLMDFLNGGSITELTGQVV"
     aSModule        complement(15072..22660)
                     /complete
                     /domains="nrpspksdomains_shmA_PKS_KS.1"
                     /domains="nrpspksdomains_shmA_PKS_AT.1"
                     /domains="nrpspksdomains_shmA_PKS_DH.1"
                     /domains="nrpspksdomains_shmA_cMT.1"
                     /domains="nrpspksdomains_shmA_PKS_KR.1"
                     /domains="nrpspksdomains_shmA_PKS_PP.1"
                     /iterative
                     /locus_tags="shmA"
                     /monomer_pairings="pk -> Me-pk"
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(join(15642..15999,16053..16222))
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_shmA_PKS_KR.1"
                     /evalue="4.70E-40"
                     /label="shmA_PKS_KR.1"
                     /locus_tag="shmA"
                     /protein_end="2327"
                     /protein_start="2151"
                     /score="129.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="KTYLLAGLTGDFGQSLSEWMVSKGARYIVLASRTPKVDARWIEIM
                     AQRGAYIVPISMDLTDRSSVLNAYSQIQANLPPIGGIVNGALILEDSEFLQTTAETIKR
                     NLGPKVDGTLLLDELSGRNVDLQFFILFGSLTGIGGNWSQSAYSAATCFQASLIHNRRS
                     RGLVGSIIHLGVV"
     CDS_motif       complement(15684..15794)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_shmA_0008"
                     /evalue="5.20E-12"
                     /label="PKSI-KR_m4"
                     /locus_tag="shmA"
                     /protein_end="2313"
                     /protein_start="2276"
                     /score="38.3"
                     /tool="antismash"
                     /translation="LQFFILFGSLTGIGGNWSQSAYSAATCFQASLIHNRR"
     CDS_motif       complement(16121..16219)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_shmA_0007"
                     /evalue="1.80E-14"
                     /label="PKSI-KR_m1"
                     /locus_tag="shmA"
                     /protein_end="2185"
                     /protein_start="2152"
                     /score="46.2"
                     /tool="antismash"
                     /translation="TYLLAGLTGDFGQSLSEWMVSKGARYIVLASRT"
     aSDomain        complement(17789..18415)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_shmA_cMT.1"
                     /domain_subtypes="cMT"
                     /evalue="2.80E-75"
                     /label="shmA_cMT.1"
                     /locus_tag="shmA"
                     /protein_end="1629"
                     /protein_start="1420"
                     /score="244.9"
                     /tool="antismash"
                     /translation="RFYEEDTGMRMMNDVLGELCSQITFRYPRMKILEIGAGTGSATRA
                     VLSRIGHRCHSYTFTDISVAFFEDAKANLEEYEDQMFYKAMDIDRDPIPQGFEEHSYDL
                     IIASNVLHATKFMKETMTSVRRLLKPGGYLAIQEVTNLDTISTSWSVCGFDGWWAGHED
                     GRKWGPMLSRDSWDELLKETGFGGIDIYTTPGDDEKVCSTSVIISQ"
     aSDomain        complement(19226..19750)
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_shmA_PKS_DH.1"
                     /evalue="6.90E-26"
                     /label="shmA_PKS_DH.1"
                     /locus_tag="shmA"
                     /protein_end="1150"
                     /protein_start="975"
                     /score="83.4"
                     /tool="antismash"
                     /translation="LLGSLEPNAGEDELRWHNYLKHDILPWLSDHRVLSRAVFPATGYI
                     AMALEAAGILASKRSTAMRLVKIQDFVISQAITLPEDDPVGVETLFRLSGIQEHKSSHT
                     TTARFDIDACTGETLQNRASGQLTILWGETDSDILAPKPPTPPGMHTLRTEDFYSFLAE
                     VGYEYLGAFRGL"
     CDS_motif       complement(19595..19672)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_shmA_0006"
                     /evalue="4.20E-13"
                     /label="PKSI-DH_m2"
                     /locus_tag="shmA"
                     /protein_end="1027"
                     /protein_start="1001"
                     /score="41.6"
                     /tool="antismash"
                     /translation="WLSDHRVLSRAVFPATGYIAMALEAA"
     aSDomain        complement(19976..20932)
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_shmA_PKS_AT.1"
                     /evalue="4.60E-85"
                     /label="shmA_PKS_AT.1"
                     /locus_tag="shmA"
                     /protein_end="900"
                     /protein_start="581"
                     /score="277.4"
                     /specificity="substrate consensus: pk"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="VFTGQGAQWAQMGYDLISSSDKAMEWMGELQHSLDTLSNIHRPHF
                     SLLEELESSSADLQKAHLSQPLCTALQIVLVRFLASLGIQFSEVIGHSSGEIAAAYAAG
                     FLTARDAIRIAYLRGLVAAQACSETHQPGAMLAAGLSPEEAAEVCRSDEFKGRVALAAS
                     NAPASVTFSGDADAVSQLEQQLKEKKTFARLLRVDTAYHSHHMLACTAPYRKALKNCHI
                     EVQIPQTATEWYSSVYPGVKITLPDHAISLGCEYWIENMVSRVSFCEAVQGVVSEGYSP
                     DVMIEVGPHPALKGPVQQTLSSVVSGEMEMPYLGLLSR"
     CDS_motif       complement(20579..20686)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_shmA_0005"
                     /evalue="2.20E-10"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="shmA"
                     /protein_end="699"
                     /protein_start="663"
                     /score="33.0"
                     /tool="antismash"
                     /translation="GIQFSEVIGHSSGEIAAAYAAGFLTARDAIRIAYLR"
     CDS_motif       complement(20885..20932)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_shmA_0004"
                     /evalue="6.70E-05"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="shmA"
                     /protein_end="597"
                     /protein_start="581"
                     /score="15.4"
                     /tool="antismash"
                     /translation="VFTGQGAQWAQMGYDL"
     aSDomain        complement(21341..22660)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_shmA_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="1.90E-161"
                     /label="shmA_PKS_KS.1"
                     /locus_tag="shmA"
                     /protein_end="445"
                     /protein_start="5"
                     /score="529.6"
                     /tool="antismash"
                     /translation="IAIIGTSCRFPGQSTTPSRLWDLLKEPRDVASVPPASRWDASSFY
                     HEDPTYPGTLNAKEGYFLTEDPRYFDAAFFNISSTEAASIDPQQRQLLETVFESLEAAG
                     QRIDQLKGSSTGVFCGQMGTDWPDFFATDHQSVPSHAATGSARSILANRVSYFFDWHGP
                     SLVVDTACSSSMVALQQAVVALQQHECPVAIAAGTNLILSPSFYIVITKMTMSSPDGRG
                     RMWDAGANGYARGEGIASVVLKRLSDAVADNDPIECVIRAIGVNQDGHTQGLTIPSGTA
                     QLDLINSTYARAGLDPRTPRDRCQFFEAHGTGTVVGDPQEAFAIHQAFFGETPQTDEQH
                     KVDDTEILHVGSIKTIVGHTEGMAGLAGIIKASLSIQNKMITPNALFESLNPALKAYTR
                     HLRIPTEAIPWPSLPEGVPRRVSVNSFGFGGTNAHAILESY"
     CDS_motif       complement(21698..21742)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_shmA_0003"
                     /evalue="2.30E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="shmA"
                     /protein_end="326"
                     /protein_start="311"
                     /score="10.6"
                     /tool="antismash"
                     /translation="FEAHGTGTVVGDPQE"
     CDS_motif       complement(21950..21988)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_shmA_0002"
                     /evalue="2.40E-03"
                     /label="PKSI-KS_m4"
                     /locus_tag="shmA"
                     /protein_end="242"
                     /protein_start="229"
                     /score="11.2"
                     /tool="antismash"
                     /translation="WDAGANGYARGEG"
     CDS_motif       complement(22130..22177)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_shmA_0001"
                     /evalue="2.50E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="shmA"
                     /protein_end="182"
                     /protein_start="166"
                     /score="19.4"
                     /tool="antismash"
                     /translation="GPSLVVDTACSSSMVA"
     gene            23258..24781
                     /gene="shmB"
     CDS             join(23258..23559,23619..24270,24329..24781)
                     /codon_start=1
                     /gene="shmB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="other (smcogs) SMCOG1087:hypothetical
                     protein (Score: 190.7; E-value: 7.9e-58)"
                     /gene_kind="biosynthetic-additional"
                     /product="FAD monooxygenase"
                     /protein_id="BBI47419.1"
                     /sec_met_domain="DAO (E-value: 4.1e-10, bitscore: 28.6,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSISSKDSGLRIIIIGGGITGLALAHFLEHAGINFVLLEKHHDIL
                     ANFGGSVGLQANGCRILEQVGVYEHLEQWMTATEFIRARLPDGFTWVYPSHLYTSMLGY
                     PLFMIRRTVLLRCLYDSLKDQSKIKVGSKVLSITRTGCSDGPLSVTTAEGAQYTGDIVV
                     GADGVHGITRAEMWRLAEPQLSEPSPEHMTVDYMCILGITQPVESLAEMIRMNGIYGTF
                     YKHVVWIVIPNKDNSVNWSALIKLDRTYAHPNVPKWSQEEVMTRLEALEEHTLDGTLKF
                     RAFWEITESISSVPIYEGIVQTTTLGRIVCIGDNVFKMSPYLAEGGNLCLESAAILANT
                     LRRLNTPQTKHTEAEISAGLRDSTAAHMARLRRRCAESYVLARTIALETWTGWFWLRYF
                     AKYTATSACYYIMTFQDAGPTLDYLPMPTRARLASKRLEQMVKKRRRTAWLSCGVAFGV
                     ISLSFLWFLS"
ORIGIN
        1 tttatatggt atattttctt tttctgtatc actggatgca ttccccgaag tcgagagctt
       61 ttactgccct ttagggctgt cggaaaccct cccctcaatc gtctagccga ctgccagcga
      121 aggctgcagt gagctgaaaa ttgggcgtga actgaataaa atagaatgga atagtgttat
      181 tggatataag aaaaaaagat taaatcataa aggtcaagaa ccccccgacc cattcccggc
      241 cctaggactc gaattccgaa actgacactc ctcatcctca caactcggca cactcggcca
      301 ctgcacctca tcgctaaaca cgcgcgcact cgacccacct tcacttcccg acgcaacaag
      361 caccaaccgc cccagaatcg catactcaag cctcaacttg atactatacg ccacaggctt
      421 aaaaacaacc tgcagcgcaa agagccccgt gtactgaaat acgacgacaa tgacgtccag
      481 aatcaatatg ataatattga tcgcgatgag ttgaaccagg ataacactgt gtgcgcgctg
      541 cggccgtaac cggaggagtt tcgccgtctc ccagatatag attgcggaca ggagcgattc
      601 ctgcaggcag aacattataa gctggatgcg ctcgatgacg ttgtacccca ctacgaacct
      661 ggactcaata tccgggttgg gcgagacagc gccgtagagg aggactgtca ctggtatatg
      721 cagcaatacc gcgtccgtaa taatgaggta tagtatcccc ctcaacacct tcgggctctg
      781 cagcacaaga tgcaacctcg accacagcac cagactatgc cccgtaacca tgcaatacca
      841 gcccacaagg ataatcgtaa cgcagatata gttggagatc ggcgcgaaga agaatagcgc
      901 gaagccgagt gtgttggtta tgagactgca tgacgagacc agcagcgacc agaagtatag
      961 cccctggtag cgcttgaatg ttgcgagggt gagtacgatc agctcaacgg agttgtagac
     1021 tgttaatgcg gcgaatgcgg taaatgcgta ttggagtggt tcggagaggg gttggttggg
     1081 ggagtcggag agcattgaag tgggatatgc atgccattag gtttaggagg gtgcaagagg
     1141 catcggggtg gtttatctgg gggatcggat gaagagaagg aggaggaggg taggaggtga
     1201 gattgattgc gcttgaagaa gggtttggct tttgacttgt ggcgaaacga aatgttatat
     1261 tcgggacata gagagtttga aggttgtttg gttcgctggg gctggagctg agctgccgtg
     1321 gaactgatga gctagaccac gccactttct catactacca ggtatgccat tccatacttt
     1381 gatttccccc ccccccccgg tgggtgtagg ctgtcaaacg aagcgtaact tacaggcata
     1441 gcgtctatat cttgagaaga gaggccacag tacaataatg gattgtaccc agggcaggat
     1501 catgcatcac gaaggaaaag atgaacatga agaaagaact cctggagcaa aataagcttc
     1561 aacggtaacc ccaagcgcac aaaccacaag agcctgctaa gagggtagaa ccaagggtct
     1621 aggcctccaa gctgggtttg ccaccaccct gaccactttc cccatccgtc cgtcctagcc
     1681 ctcgagacga aggttctatc ccgctacccc ggagcaacaa cgtcggtcca gaaccatgtc
     1741 gaattagaaa gcagaacaca aatggccatt atatcagcac gtgctcttgc ccatgattgt
     1801 tttcgttagc tatccccgga tcattgcgac gatcggctga ggttgggtaa atggccgccg
     1861 ggctgcggca aaggcacacg gagtgcacag acgcatttct cttccggtgg agactttaca
     1921 caacgggtgt gcatctagag ctataggcgg ggagacatgg ctctttttac tttgctggtt
     1981 cgtacctcct ctagtccaat tgctcaaaga cctttttcac cgagatcatt ggtcacttag
     2041 gttcgcttgc tgaggcgttg atgctggtgg gaaagacggg gtagctaaag ttgggtttgc
     2101 gcgtgtggtc tttcaaatac tggccgtcta ttcattggag attgtttagc aatgcctggg
     2161 cgggagttta aaggctgaag ttttaagagg taggtaggtg gctctgtggc ccggcacaat
     2221 cttatatctt tatcagagac ttaacgatgt ataagcgtaa aagagaaatc ggggcgccgg
     2281 gttgattgtt tcaagaagct ttgagaaagc tttcattcgc agtcgaaagg tatgtaaaac
     2341 aggaggacaa caacaaagta tgcgctatat acagttgttc aacgccaccc agttaactgc
     2401 cctagagaac agccctgatc ttccctccca cgtctccatc tgtctcctct ccatcactga
     2461 gtagcctctt cccatccgga tcaaacaccg gctccggcac aaccgtcgcc ctaaccctct
     2521 tcccgaaata ttcaatctcg acacccgcgc cctcccctac acccccggga agccacgcat
     2581 aaaccacggg cctgcgcaca ctaaacccaa acgccgcggt ggtgacatac ccaaccggct
     2641 tcttgttgat gaaaacgggc tccttcccca tgaccattga ctttccatcg tcaatcgtaa
     2701 gacatcgcag acgccttgtg agaggctgtt tgtttcgtcc ctctagcgcg cccttcccca
     2761 cgaaatggtc tttcttcccg ccgtcaatag caaagcccaa ccccgcttcg taaggatcat
     2821 actcagtccc aatatcagcc ccatacgtgc gatacccctt ctcgatccta agcgcattca
     2881 gcgccgcccg gccagcgggt acaagaccgt gcggttttcc cgcggcgtaa agggcgtccc
     2941 agagacgacg gccgtgttcg gcactcgtct ggatctccca gccgtattcg ccgacgtagg
     3001 actttcggag gaggagggtc gggattgagg cgattgttgt cggaagtgcg tgcatgtatg
     3061 gtagattggt gtttgatgtt gttgatgccg atacgcgggc ggatgttagg acggagcggg
     3121 cgcgcgggcc ccagagggct aggctgcatg ttgcgcctgt tatgtcggtg acggtcactt
     3181 ggacgctgct ggtgctggta gaggtagagg atgaggtaga caggtgccgc gcttgtcggg
     3241 aaagatacgc aaggtctgtc gctgtgtttg cgccaatctg gtatgtattc ctatcgagtc
     3301 tcgtaacgaa gatatcgctt cttataccgg cgttctcgtt caagaggaga gtatacacga
     3361 tcgtcccagg cttcacatcc acctcggatg tcgtgagcgt ctgaagaagg gctgtcgctc
     3421 cagggcctga gacaaggaaa cggtggaaag acgacatatc atacagcgcg accgcattcc
     3481 tcgtcttcca cgcctcgacg gccgtaatcg gtgagtagaa tctgttggac catgtatcgc
     3541 gctcgacggg cctccactca ctcggcaggg actgtaggag actcttattc gattcatacc
     3601 aaaacggccg ttcccacccc ccagtctcga aaaagacagc ccccagctca acctgcctgt
     3661 gatagaacgg actcgtccgc aagcccctag gcgaactacg cggctgcaaa gggtggagga
     3721 tatcataaat ctcgacgaaa ttctgctgac tcgtctcggc cacgtaatcc cgattcaact
     3781 gcacattctc aaaccgcgac agctcgcact cgctaacgtc gatgtcgctc caccccttcg
     3841 tgagaatttg ggccattgcc cgcgcgacgc ccgcgctgtg cgtgacccag actgcttcgg
     3901 cgacgaagaa cccgtcaaga tttgggcttt cgcccaataa aggcccgccg tctggtgtga
     3961 atgagaagat gccgttgaag ccgtcgtcga gttcggttcc tgccagagcg gggagaagtt
     4021 tcttcgtttc tttccatgcg ggtgcgaagt ccatctccgt gaagtctagt cgcgagggca
     4081 tattcttctc gtcgacttgc ctcggcgtgg gaccaagttc acccgcgaca acgggcatgg
     4141 gcttgtgtcc gtagtatccg attccatacc gatcgccgtg ttcgcggtag tataggtctt
     4201 gatcctggtg gcggagaata ggcaatgacg cattaagccc gttcatcctg ctattcacgt
     4261 cgcggtttgc gagggccgca acggggcccg ttttcgcgta ctggtgggca agtggcagga
     4321 gggggatatc gacaccagcc agcgcaccga tctcgacgcc ccagaagcca gcgcaggaga
     4381 ttaccgtgtc cgagtggatg ggaccggccg atgtctcgac gcctgttacg cgtccgtttt
     4441 cctgcgttat gcccgttacc cttgtgtgag ggaggtacgt aacccccttt gcgctcgtcc
     4501 gctcgatcaa gatttgcgtc gcgcgagcag cgagggcaag accatcactc ggaatatgta
     4561 atcccgccag aacaacatcc ctattcaaat gcggatataa agccagacat tcctccttcg
     4621 aaatcaacct cgcatcaacc ccccaactcg tcgcccagcc atgtctcctc ctcaactcct
     4681 ctacgcgctc cggcgtcgtc gcgacctcga gcccaccaag ctgattaaag cacccttgcc
     4741 cgtccttttc aaccgagagg agtttctgca cggtatatga ggcgaacttg gtcattgttt
     4801 ttgacgggga cgtttggaag acgaggcctg gtgcgtgcga cgtggacccg ccggagaggg
     4861 agagcgggcc ttgctcgatg actgttatgg ctgatgcggg ccatcctgat gataggagtt
     4921 cgtcggcgag gtttgtgccg actatgcctg cgccgattat ggtgatgttc tgggaggcgg
     4981 ggcgtgaggg tgaggaggaa gctgaaggag gcattgtaga agtgggagtt ctgtgatcgt
     5041 cactcgttaa ttcgttcaat caatcaatca ttttgttgtg gcattggcag ctagatctgt
     5101 agtatagcta tagctctata ctctgcctat cagacagagg gagggtccag accccgcagt
     5161 ggcccacggg tccgtggccg tgtccgggct gcatgacagc atccctccat cattccgtgt
     5221 gagagaccgc ttccgaaccg attcctaggg ctccgtttgg aaggattcat ggaccagcaa
     5281 gccagatacg gaagatacgg cgtgcatgga cagtgataag ggtggcggaa aagtcggaag
     5341 tgagccggac cccgcaagag agttgtttta aactgatagc cagtccatac ccgattaggg
     5401 caaaagttcc aggcttcctg tttgggtgtt gctaagaata cacctgcgca gaacccatat
     5461 ctgcggggta agctcgcgtt gagctacatt acgtcctcac gttggcccct gcagcgtgct
     5521 gtggaaagcg aggcatctcg tctgcattgc cccgattgta ctagctaaag ctggagctcg
     5581 cataccccgc attctactca agggacatct tacgctccgc cgatggggac tcattgagcg
     5641 catatagagt aggaatttgt gcagtgagca ggtactaact atggaatgcg gaaaatggtt
     5701 ccgttgtgca aagggcttgg ggattccacg gaatccgttc aagggatgcg agggcggtgc
     5761 ccgacccctt tcttctcctc accttggcta gttagaacta ctgcgcagtt gcaatggata
     5821 tgtgggaccg taatgtgtac tgatcaaggc cgcgagacgg gcgtcacgcg cagcagcagg
     5881 gtaggtgcag tgggatccta gatatcgtta acagtgatct tcgtctacct gtgggttgcg
     5941 tggagaatgg gtgcatgggg acaaagcgcg atggacccgt tcaagctgct taggaccgtc
     6001 attttccgcc agcggttgaa gatattctgg gtcactccag gtttgggtat actgttgttg
     6061 gctgtttgag taccggaggc gctgcgtggg agttgtcgcg tgtggattcg gtttggtatg
     6121 gtcgctatgg aggagtaatg gcggcgtggc atccgggcac tctctggtct ctgcctagca
     6181 attgacgagc tttggtctca gcaccgagat tcgcgagaag atgagaacat gttcgttcta
     6241 gacaagtcgt acgtatcgca tggatcattt ctatagattt ccgagattcc accaagccga
     6301 gccttcgatg tctcccacaa cgggtgccga gttgtgatac tcgacgtcgt ccatatttcc
     6361 aaactgcgtt gagtcggccc agagccatgg ggtgtttagc ataagactgt caacaggagc
     6421 aacgagtgga tcgcgtaacg aggtgtttcg aagggactct gcagtggctg ctgtgggact
     6481 tcggtacaat ggcataggca cagcctggcc accatcggtt gtattgacgc tgacctcggg
     6541 cgatgctgta acaatgatat caacagtagt ggacgcctcg tttgctggcg tggagatgaa
     6601 ggcaggtgtg agagaaggat gcagcaacgt ttctcgcccc gactcgtcag tgacattata
     6661 ttgtaggata tcccacatta gaggaatatt tagacgaatc ttggacggga cccagtcatc
     6721 gagatccagt atatcggaac cagatgcgat gcgggtgagc tcatccaact ttcggctcta
     6781 tgaggggtta gatcgagttg cttcattgtg caggtggtac ctactaagcc ttcgcaagca
     6841 cgcgaaagcg gaacgaagct gcgaagaaaa tcactgcatt tcgcaagatc tgctcgtgac
     6901 ttgtacttta gccggggatc gtcagcgcag caatagtata actggacact ggctgcgatc
     6961 gcagcgacat ggccaaagaa tggatcggcc agccggagtt tcttctcaga aaccatgtcg
     7021 atcaagcgaa ctatccaggt tgcgtgtaga agcacgagtt ccgacgaccg gcgccagaag
     7081 ctattgggaa tggcaagatt ggggttgtac tgtgaagcga tgatgtataa gaagggatgg
     7141 ttgaggacgg tgagagtggc atggtacatg aactgcagct tcacccaagg cacccagtag
     7201 gctcggttta cggcaagctc ctctgctgtt cttcggtaga actgcacatg ttcatatcgg
     7261 tgacataggg gggtgctgtt ttcgatctcg gtcaagtcgg agagcaccac agaatacatc
     7321 gactcgtgcc tccagggctc tgtgagtcga ttgctggcgc agtgcgatac gtatgcccgg
     7381 actttgctcc atacccagcc aaagtaaatt gacatgctcc agatgccagt atcatctggt
     7441 gaggagcatc caacagtatc tctcggtggt ggtggtggat tcggtatgct attcttttcc
     7501 tgctccatgg gtccaccgct agaaaggtac ggtggcctcc atgtcgcggt tggaatgcta
     7561 aggaggcccg tttgtcgccc gtatgactgt tccaatattt gaaggctcca aaataggcgt
     7621 ttcttttgct ctgcctgccg atcctcacgt acatacgctg cctcagtgtc tagcatggct
     7681 gctcgacata gctgcaatcc gagtcctaaa tagaaacgtc caagttgcaa ctgtccgtct
     7741 gtgcaaagtc agcgtcactc ggtcggtaaa ggtagcgacc acttaccgat gaatgaagag
     7801 taagcgagga ggcagaggct ttcgattgtt gcgagttcaa cagtcccatt tgcaatccgc
     7861 agcatgatca agctctttgc actatccgca taccgatgcc cctgctctgc ctctcgtgag
     7921 aatcgcgaag tcaaggcgag aatactgcag ataagctcct ccggatggga ctcgatattc
     7981 gcaagttcct tgatattgaa acaccaaacg ggctgtcgat ggcagcattc gaggtagagg
     8041 tcgatcgcct tcgtaacagt aagtgacgaa gcctgcggac taccatcgtc cagcccaaat
     8101 atcgaaaaga aggcgttatc ttgagtgtag ttcacgtcgc catgcgaccc tgtcgttgga
     8161 aaatcgggcg catcttcgat cacttgctgc tgctgttgct gatgctgttg ttcatggtga
     8221 tttgactggg cagcaccccg cagtatctga ttcacttttt cttcgagctc agcgagtcgg
     8281 tctttctgtg gcatgtatca gcagctgcct tcattcagtt ttaggatgaa tggaagaata
     8341 catttagacc gctcgttgag ccgcccgccg cagcatagga acattgctga tttagacgaa
     8401 cacagcacga acaagccggt ttctcaccag gacaccgtgt ctttttcctc ctgcagttga
     8461 tgcaggcgtg attagagcgt agccgccgcc gcgtatcggt catgtctcac agacagcagg
     8521 cacaaggagg gctagcaagt ggcgagaaag agatagagat gcggtgagaa taaacacacg
     8581 agttcagcgg gtgatccgcg accagagaag gcttcgaaga cgctagctag gtgtaactcg
     8641 agcaatggga gggtaaaagg agatagaagg gaaggagggg gtttcaacat gacggtactg
     8701 ggcctccgca tgggccacct gccactggca ctcgaagact ggactaactg ctgctatctg
     8761 cggggtcacg gggcgggatc tgcgccccca atcgggaagg cgccaccccc cacctgaagc
     8821 tagggctgct cccccccacc aatagggacg ctctcttaca catacaactc ggatattgtc
     8881 cgagtctaga taaggacagt aagcaagaag cataattttg tcattagcaa actaagactc
     8941 attattcgtg aaactgccag tctaggagta gggaagaaaa caagacgcta acaaaacaaa
     9001 atctagatct actttgcgcg gactaccaag caatagcagc cggtctctgt gcaccaatgc
     9061 tcgagcagca ctcgccgccc tcaggattac agctcaagct agcgcagaac tgctcatcct
     9121 ttgcgctggc agtggcctcc ttaggcaccc gctgtctggc cggccagatc tcctgcttct
     9181 ccatttgctc cttctcaaag tgctccgtca ccaggtcacg caccaccttc tggaagtaca
     9241 gcggtccctt ctccatcgtc gggtggagct cgccgttgac gaagacgcct gtgttgagat
     9301 tcttctgggc ctgtgcgcag aggtccttgt cctcggacat gactctcttg tagatggaat
     9361 cgatcatgtt gaagtcctcg tcgctggagt tcttgttgcg gaagacttcg tacttcatga
     9421 tcgattttgc gggctcgagg gggacgaagc gctgcatgag gatgaagtgc ggggagacgg
     9481 tcatcgatgc attggggaag tagtaagtag ctgcgacctt caatcccgct gcaatctgct
     9541 ccggcttgga gtgggcgtcg tggatgatgc ctgcgtcctt ggtgtcgacc gagtaggtgt
     9601 tcaggtctgc aatcgaggga atgtcggggt gcgttgtcgc gcagtggtag cactcgttgt
     9661 agttgtctgc gagaatcttc cagttgtagg gaccctccat ctcccaggtg tggtcaaagg
     9721 cgtactcgtc ccagttgatt ccctggaacc ggggctgcat atcgatgccg ccaaagtcct
     9781 gctcccagga gatctccggc tccgggctcg cgtccatgtt cacccagatg aagccattgt
     9841 tatcgatgtg cacatggatt gggagaaggc cattcttgct cttgtcaaag ccggcgaggt
     9901 cctggtagcc aggagccttg gccagcttgc cgttcagacc gtaggaccag ccatggtatc
     9961 ggcaagcgaa gatacgggca gtgccaccct cttcagtaac gacgggaaaa gcgcggtggc
    10021 gacagacgtt gtggaaggca ttaatctcgc cctggcggtc tttaacgagg atgaattgga
    10081 aaccggagac ctcgtagcga agccagtcgc cggcgttggg gaggcgcagc ttgtgggtcg
    10141 tcaagagcca cttgcgggag aagatggcgc ggcgctcgag ctcgaacatc tcctgcgagg
    10201 tgtaccagga ggagggcagg gccctgaccg cattcttgtc gtcggcgggc ttggctgcgg
    10261 aggagcccac gccaaggtag ttccacagtg atgacatgtt ggagtgtgta tagacaagtt
    10321 atggagaact tgttgtgata agcttctttg cttgagatat ctttgctgta gatagtcgtt
    10381 ctgatgtcgt atctggctgt ggatcatgag accttgatat aggaaactca tcctctgcct
    10441 ttgaatctac aacacctcat cttgacggtt gtccagacca aagacctaca cggagccgtt
    10501 tgctgtcccg acgccacagc gagatagcga aggaaggacg gttcaccagc ctggcagcca
    10561 tctcaaactc gaaaagccag aagccgggcg cgcttgctca gatgttgcca gccggggccg
    10621 tggcggagat agagacccgg ctcacggctc acctcccgtc ccccgatctg catccatccc
    10681 cggacccgtt ctgccgtcat acttgcctct tagtctcggg cttcccaggt caatagcaaa
    10741 gataagtatg ataggcagca gccctaggcc aatgataatt ttacgtacgt gggtaccgcc
    10801 catactgcgg cgcagcgggc tatccgcggg aaacatcccc acagcgtata ctctgtagag
    10861 tgacaagaat ctgaacacga ggaatagatg aacttctttc gcttagtcga ctcagaggct
    10921 ctcgagctct ttgggggtca tgtgtgtcca tccctcagtc ctgtagtctc tggagtgatg
    10981 gatgaccccc atcactacgc ttggacatac agggacagcc cgcaaattca actcggacac
    11041 agtggaaacc ttccctaggg cagtttcaaa aacctctgac tccctgttag atccaatcat
    11101 cctctttagg tcatgtagct actccaattc tatcttcaac taaccctatc ttcaaagcca
    11161 tccccgcaga gtccgtcggc aaagataggg aaagggtatg ggggccattg cccgcatgac
    11221 ctagagccat tggggaaaca ggtgcttcga gaagtccaat agccatctct gaattatatc
    11281 gtaaatcatc actagagagc ttctagcgct ctggtcgaaa gcttccccgc attcatcata
    11341 gattggcatg cacaagccct cattcgaaca tctgtatatc agagtcgtgt acataaaagc
    11401 actcatttcc cttgtactaa tctctttgta catcgtctcc tgcacagtgc agtccttctt
    11461 ctttatttag atttgctcaa catgtcgcca cctcaagata ccgatatcca gggcaaggag
    11521 cccgagaaga caaccaaaga caacaacgcc gcgccctcct tgctagcaga catgcctggc
    11581 tcagtagccg aacacggaac agagcataac ggcctccatc gacaactcga aaaccgccag
    11641 atccaactca tcgccatcgg gggctctatc ggcaccgccc tcttcgtcag tatcggcgag
    11701 ggcctgagcc agggcggacc tggcagtctt ctgatagcct actcaatcta ctgtgtcatg
    11761 ttgtccctgg taaataattg cattgcggaa atgactatat acatgcctct cagtggttcg
    11821 tttatccgac tcgcaggcaa atgggtggat gaggcgtttg ggttcatggc tggatggaac
    11881 ttctacttct atgaagccct cctcgtgcct tttgagatta cggcgctgaa cctcgtgctc
    11941 tcgttttgga gggatgatat accgattgca gcggtttctg tggcttgcat tgtgctttat
    12001 gcgtgagctt tctctctcct gtgctatggc tctagaaccc catgggcgcc ccggctctcc
    12061 ctccatgatt ctcagcacca agtctcttct ctcacacgtc gcttgcacga tcattgaaca
    12121 ctaatattgt ttcttgtata gactccttaa tatcctggcc gtcaaagcct acggcgaatc
    12181 cgaattctgg ctgtccagcg gaaaagtcgt acttatcctc atcctcttct tcttcacctt
    12241 cgtgacgatg gtcggcggca acccccagag cgacacatac ggcttccgat actggaacga
    12301 tccgggctcc tttgcaacac actcatccag tggtagccta ggccgcttcg aaggtttcct
    12361 cgcagcactc tggtccgcat gcttcacctg cgtcggcccc gaatacgtct cggtcgtggc
    12421 agccgaagcc aaattcccac gcacctacat caaaacagcc ttcaagacag tctactaccg
    12481 cttcatcgta ttcttcattg gcggcgccct gtgcagcggc attgttgtag cgtacaacga
    12541 cccgacctta gtccaagcag ttacgggcga gggctccgga acggcagcag caagcccgta
    12601 cgtgattgcc atgcgcaacc ttgaaatcca ggccctaccg caccttataa atgcccttct
    12661 tgtcacaaca attttctccg ccgggaatac gtatacgtat tgtgcaacta ggacgttgta
    12721 cggtcttgcg cttgatgggc gcgcgccgag gatctttacc aagtgcacta agcagggggt
    12781 tccaatttac tgcttcgctg tgacaatgct aattgcctgt ctttcattcc tgcagctgag
    12841 cagtaattcg tcgcaggttt tgtcgtggct gatcaatttg acgacggcgg cggggattat
    12901 cgactatatt gtcatgtgcg tcacgtatat ctggttttat cgcgcttgta tcgcgcaggg
    12961 gttcgaccgg tcgactttgc cttataccgg ctacttccaa ccctggtgcg ggtatattgg
    13021 cctcgtgtgg atggtgctgg tcgtgacatg ctacggctat gaaagcttca cgccatggga
    13081 cgtgacctcg tttttcacgc attacaccat gatcattgtc ggcgcggtac tctataccgg
    13141 gtggaaactg cttaagaaaa ccagactttt gcgaccacac gagctggatc tttattggga
    13201 ggcgccgcag attacggctt atgaggaggc tttgtcactg cgtgagccgg tcactacgtt
    13261 ttggggcgag gtcttctcgt tcttgcgtcg ggataagggc aggaatgtgc caggagaggc
    13321 tgtgtcggca tgataccgtg gtttctatat aatgtaacat gttcgtatct tcatcaaatg
    13381 ctttgagctg gtccaaaggc gaaaacttgg ttgtgttggc cagtgcgtcg ataaatatat
    13441 ataactgcac caaggaagta ataaatgcag actgaatcaa ccagtgtata cctaaaggct
    13501 gtctacacct cagcgatgta agctcttcat aattccaacc acagaccaaa acaaaaagca
    13561 caaaggacaa cggaccaccg cttccgatag acgggaacgt cgcagcccgc tcccgtacac
    13621 ggcaggggga aacagacacc tcgtaggcca cgacgctgtg gtcaacaacg acacctgaga
    13681 cctactgtat ccaacacaca atcatttcaa acacttggac tttcctccta gagtcagatt
    13741 cacgaggacg gcccactccc cactacctat ctctcgctat ctttgatctg cgccaagacg
    13801 gagcaggacg gctcggagcc ggaccgcggg gtcggttcac tcagtttgcg ggggataaga
    13861 tggccatggg aaattattgg tgagacctaa ctctgtctat ggaggatatt cggtagtaaa
    13921 ccatagtaag acgcttggct ataccccagc tctatgcctc ttgttgtacg ccaaagcttc
    13981 ctgtactctt actattaaga ctacccaagt cgcccacgat aaacgccgta gctgccacgt
    14041 ctgacttcgt catggatgag aatggtatca ggactcactg acggacagtc ggtggaggcg
    14101 aaccacaagg ggagagaaca aagcggattt ggaacaccac tagattatat agatacgatt
    14161 tatgccttct gctacggcca ccagctctag ctcattcgac ctttcgcccc aacactactt
    14221 attatccccg agtgttacgg agtagattac tgtatttagt cacctttgtc cctaaggtct
    14281 ttgcgactgg tacctagcat gtagtgtcga cccgcggact cagcacagtc ctccaagcgc
    14341 agcaaggcgc gcaaaacggg ctgagtaatg agcttccttc ctcgtaagga gagtttcatg
    14401 acaaaagtca agctcgattg aagcttgacc ggcctcgcca ggtgctgtga gtcacttccc
    14461 tgcaagtatg ctgtcaagaa cgtgggcatc tgcgccccgt gggcagtgga cacgccgatc
    14521 ttgtctgggc cttacaccga ccccgaattc tgccagctgg tgacgttgca ttgggacact
    14581 ttgctgtttg attgagtttc tggtttctca ttctcattct cactctcact cgcgcgtagg
    14641 tggtagcgtt gtgaagtagc gtcggtaagt tgtagatgta acgaggtcca agcgaaggag
    14701 ctgagctgat aatatataac gatttaggga atggttaaga gtaatctctc atgaaaggcc
    14761 ggctcagagt ttggtattaa ctttagacat aggggcgccc ttatccccca agacacccag
    14821 tatgaggaag tgaagtccgg gtgattttat gttcggattt tgatactcgt accgtgacgc
    14881 agggcttgaa tgtgaggagg acgagtagta ctcaccagcc gccgacaata tattcgaata
    14941 ttacagcata tgatgagcga ttagctattg cctggcacca cactatctaa ctaatgcttt
    15001 acaccgttta caccatttgc catcttctcc ccatcccctc cgtttggaac agatgtatcc
    15061 gataaaccat ccacaacctg ccctgtcagc tccgtaattg accccccgtt caagaaatcc
    15121 ataagcggga tctcaacacc caactccttg aaaaaccacc tccgcaagtc aaccgcaaca
    15181 agagagtcca ttcccagatc ccgaaggtaa gtcgcagacg agagcggata atcatcagca
    15241 agactaaact tgctgcggac cttgttcttg atagccgcat cgataatggc cgctacttcc
    15301 tcacgcgtcg tggcggattt gagttgagcc cttactgaac tagcagcctt accgaggccg
    15361 ccaacatgat ctttgttagc gttggcacgg tagtcgacgt agtcccagag aatgggcttc
    15421 tggaatcgag cgaggtcttc gccgttgttg gtaccatctg tacggtaggg ctcgacgccg
    15481 ttgatgattt ccgggttgcg gccagacgca ggatccccgg ctaggattgc ctcagcgaac
    15541 atccggtcaa catcgcgttc cgagagtagg tacgagcccg ttgtggctcg gacgtggttg
    15601 atcatgtcgg tgcccatgcg ggcgatgatt cccattccac tcacgacgcc caggtgtatg
    15661 atacttccga ccagaccgcg tgagcgccgg ttgtgaatga gacttgcttg gaagcaggtt
    15721 gcagcggagt aggcggattg gctccagttt ccaccgatgc cggtgaggga cccgaaaagg
    15781 atgaagaatt ggaggtcgac gttgcggcct gagagctcat cgaggagaag ggttccgtcc
    15841 accttggggc ctaggtttcg cttgattgtt tcggctgttg tttgcaggaa ctcgctgtcc
    15901 tcgaggatga gggcgccgtt gacgatgccg ccaatgggtg ggagattggc ttgaatctgg
    15961 ctgtaggcgt tcaacaccga tgatctatcc gtgaggtccc tggattgcaa gtcagcttgt
    16021 tgcgcttatt caatggttat atgtctgctt acatggatat tgggacaata taagcaccgc
    16081 gttgggccat tatctcgatc caccgtgcgt cgaccttggg cgttcggctg gccaggacta
    16141 tataacgggc acctttgctg accatccact cagagagcga ctgcccgaaa tcacccgtga
    16201 ggccggctag gaggtaagtc ttatccttgg aaaggttgac aagagagatt gcgggctcga
    16261 tctgggtggg gacggtgcta cactgtgtcc agtcgacgag cgcgccaaag gccgcacgct
    16321 gcgttgaaag atcacggcag gcaatcatct ccagggtgct tccgttagct gcgttgtcga
    16381 tgatgcatga ggcggattgt ttgagtctgg caatgagttg ctcgccgaaa ctcagagtgt
    16441 tggcgttgcg gataggtctg agctgctgga cagttttctg gggaacgagg cactggattc
    16501 ctggcagggc taactcagtg tgagaagcca gcagcccata gtctccttcc ggtcctagac
    16561 gaacagcgac cgatacatct cgtggtaggg tgcgtttcag gaattgcgcc gaagcgccgg
    16621 cgggaacgcc atgtacgccc tcgccaacgg cggaggcatg agtggaaata aagaacgggg
    16681 caacattgcg ctcggcagca gccctggtaa ttgctttgcg cattgagtac cccgacccga
    16741 ggacaaggag cgatgaattc gtgtcagcca ggtcagccac aaaggttgcc atgattatct
    16801 cggctgctct actaaggaat gcagcttcct gctcggtcga cacacaagtc gggacgtccc
    16861 aggtccattc ccgcggaacc tgcatggaat atccgtgctc agatgagata gcaagcagcc
    16921 gtgagccagt gtttgcgtcc actcctagta caaggtggag cgcaatcgca ttctctgccg
    16981 gcagtgggtc gagcgtcgaa taccgaggcc ttagcgagac aaactcgttc cctaaagtcg
    17041 gtcgttcctt gtgagttgac atccgaatga catgctgcct accggacgat ggaagcacgc
    17101 ggacatttgt cttgtagaga tcgacatcct tggtcaccct ggttcgaacg gccgtatatc
    17161 ggtcgttgcc atccggatcg tcaagtaaac gggtaatctg taagataccg tcactgtagg
    17221 agagttccag ctctgttgag tgaacatgag taggcagcat gaaatcattc ggtatatccg
    17281 tatatacaag tcgcatgaga gtagtggcaa gaagaggtgc ggatgcatcc ttgcggtcag
    17341 caatattcag atactggtac aaagacttcg gattctcctg gacgagtgac ttgagccatc
    17401 ctttgctcag tccatagtga gggtattcag tctccgtacc catggttacc cacagcatgc
    17461 acttggctct ggcgactaga tgctgcataa agcgtagccg gtcctcggtg agatcagtaa
    17521 gccatgagcc ttctaggtca ataaaactga gaatggcgag tccgttggta tcggatagtc
    17581 ctgcgagctc agcggagtca agtgatggag cgtgaataac gcgggtgaag cgaggctcaa
    17641 ccagcgaaaa cagtccagaa acaagaggtt tgatcgagtc cagcattccc ccaagtataa
    17701 ccaggtcggt tggttgtgaa ggtaacaaga gagactcggc gcaagagttc atcggctcgc
    17761 gaaggagtct tagacgatcg tcgacagcct gggatataat gactgaagtg ctacaaacct
    17821 tctcgtcgtc gccgggcgtg gtatagatat caataccgcc aaagcccgtc tccttaagaa
    17881 gttcatccca agaatcccgg ctgagcatcg gaccccattt gcgtccatcc tcgtggccag
    17941 cccaccaacc gtcaaatcca cagaccgacc agctcgtgct gatggtatcg agattggtta
    18001 cttcttggat tgccaggtaa cccccaggct taagcaggcg gcgcacagag gtcattgtct
    18061 ccttcataaa cttggtcgca tgtagaacat tggaggcgat aatgaggtcg taggaatgct
    18121 cttcgaaccc ttggggtatc ggatcccggt caatgtccat ggctttgtag aacatctgat
    18181 cttcatactc ttccagatta gcttttgcgt cctcgaagaa agcgacagag atatctgtaa
    18241 aggtatagga gtgacagcgg tgcccgatgc ggctcagcac ggcgcgggtt gctgaccctg
    18301 tacctgcccc gatctccagg atcttcattc gaggataacg gaatgtgatt tgactgcata
    18361 gctctccaag cacgtcattc atcatgcgca tgcccgtgtc ttcctcatag aaccgggtga
    18421 gaacatcgtc tttgcgcacc tcttcaagca gcagcttctc gccgcggaga aaagggacca
    18481 cgttggcaaa taccacggca gacattcgag cctctgcaag atgtgacata ggttgaagga
    18541 acgtctcaag ctcgtctctg gtgtggtcaa gccactccgg gcgcagaatg gggtgctttc
    18601 cctcgcgggt cagcgagagg acgcgctcca tccacgccac gacggtactg cgatgccagt
    18661 ccagcccttg ccggtcttcc ggcgtcaatt gctcatacgc gaacttgacg taaaggagca
    18721 cgattcgctc cagggattca aaatagtcag agacttcctt tgaccgaggt ggcaagttcc
    18781 agctcatact ggggaaggcc gggcccttga cgagcttgga aaacagccgc cgctcctgca
    18841 atggttgcga cagcggtgca atgtcaacgc cctgcatctg aaccaagccg tgcccttgtt
    18901 cagtgaagag atcacagtcg ccggatatgc catccgcatc aagctttgcc gtagctcccg
    18961 ttgccgatag aacagtaccc gcggcacgga cgccggccct accacagaag gcgggattga
    19021 tgagaactga tttgatgcga acaggcacca gtagggtata gatctcgccg tcatccggtg
    19081 caccaagagc agcaagcagg acttgaagcg tcgtatctaa cactacgggg tggaatagtg
    19141 ggctgagctt cccgccgtcc tcctcgattg caatactatt cgataattct gccatggacc
    19201 gatctttttg acgggcgatg gattgtagtc cgcggaaggc gccaagatac tcatacccga
    19261 cctcggccag aaaagagtag aagtcctcag ttctgagcgt gtgcattccc ggaggcgtcg
    19321 gcggcttggg tgccaggata tccgaatctg tctcacccca gagaatagtc aactgacccg
    19381 aggcacgatt ctgtaaagtt tccccggtac aagcgtcgat atcgaatctc gcagtagtcg
    19441 tgtgacttga tttgtgctct tgaatgccag ataacctgaa caacgtctcc acccccacag
    19501 gatcatcttc gggaagcgtg attgcctgcg atattacaaa gtcttgaatt ttgacaagac
    19561 gcatcgcggt agatctctta ctggcgagga taccggcagc ttcgagagcc atggcgatgt
    19621 aacccgttgc tggaaagact gcacgagaca gtactcgatg gtcacttagc cagggaagta
    19681 tgtcgtgctt gagataattg tgccagcgta gttcatcctc gccagcattc ggctccaagg
    19741 aaccaagaag caggttggga gcccctcgcc tcagtagatg ctgcttgacc ggccgcttaa
    19801 aacaatccgt tggcttttcg tgaagaaatg ggtaactagg aagtccgttg atcggtttcg
    19861 gtctgaacga ggggtcgaat tggcggatgt agctcgcaac atccactgca ctgggcccaa
    19921 gatagcccca taagctcccg atcgcaaggg ccatcgtttc aactccgttg cccccgcgtg
    19981 atagtagccc gaggtacggc atctccatct cgccagagac gacagatgag agtgtctgtt
    20041 gaacggggcc tttgagagct ggatggggcc caacctcaat catcacatcc ggactgtagc
    20101 cctcactcac aacgccctgg actgcttcac agaaggaaac gcggctgacc atgttttcga
    20161 tccagtattc acaacctaga gagattgcgt gatccggcag tgtgattttg acccctggat
    20221 acacactcga ataccattcg gtcgccgttt gtggaatctg aacttcaata tgacagttct
    20281 taagggcctt cctgtacggt gcagtacagg caagcatatg gtgcgagtga taggctgtat
    20341 caacacgaag tagccgggca aacgtcttct tctccttcag ttgttgctcc agctgggaaa
    20401 cagcatctgc atccccagag aaggtgacac tcgcgggagc gttgcttgca gccaatgcaa
    20461 cgcggccttt gaactcgtcg cttctacaca cttccgccgc ttcctccggg gatagcccag
    20521 ccgccaacat cgctcccggc tgatgagtct ctgaacaagc ctgcgcagca acaagacccc
    20581 gtagatacgc aattctgatc gcatcacgcg ccgtcaagaa gcctgccgca tacgcagcag
    20641 caatctcacc ggaggaatgg cctataacct cactgaactg aattccgagg gacgcgagga
    20701 agcggacaag cacaatctgc agagcggtgc acagtggttg cgacaggtgg gccttttgaa
    20761 ggtctgcaga ggagctttcg agttcttcta gaagggagaa atggggtcgg tgtatgtttg
    20821 acagagtgtc cagggaatgc tgaagctccc ccatccattc cattgccttg tctgaggaac
    20881 taatcaggtc atagcccatt tgagcccact gggcaccctg gccggtaaat accccaacaa
    20941 tgcgcttttg gcctcctaga ttgcgctccg tgacgcaagg taatgcctcg ttccgtcttg
    21001 ccgcttgcaa tgcacctgtg acctttgcga gcaatgccgc attgtcagtg gcagagagca
    21061 ccaatcggta cctcaaagcg gatttgcggc agaggagagt agctgcaaga tccattggga
    21121 aaacagccgg gttctctcgg aggtattgtt cgtacgattc caggacagcg accagagatt
    21181 tgccagacgc ggcggaaaag gtaaatggga gcagcatgga tgtagcgcgg gtatggccgt
    21241 tgaccccatt ggtaacaccg ttggtaacac cgttggaaac accgttggag acaccgttag
    21301 acgcggcatt ggaagcaccg ttcaatagct ttttaggctc gtagctctca aggattgcgt
    21361 gtgcattggt gccgccaaag ccgaacgagt tgaccgacac ccgccgagga accccctccg
    21421 gaagcgatgg ccacggaatc gcctcggtgg ggattcttag atgccttgtg tacgctttca
    21481 aggcaggatt cagcgattcg aaaagtgcgt ttggcgttat cattttgttt tgaatggaca
    21541 atgaggcttt gataatgcca gccaggccag ccatgccttc agtgtgacca acgatggttt
    21601 ttattgaccc aacatgtaaa atttccgtgt cgtcgacctt gtgctgttcg tcagtttgag
    21661 gggtttcacc gaagaatgcc tggtgaatgg caaacgcttc ctgagggtcg ccgaccactg
    21721 ttcccgttcc gtgagcctca aagaattgac agcgatctcg gggggtgcga ggatcgaggc
    21781 cagcgcgagc atatgtgctg ttgataaggt ccagttgcgc agtacccgat gggattgtga
    21841 ggccctgtgt gtggccgtcc tgattgacac cgatggccct tatgacacac tcaattggat
    21901 cattgtcagc tactgcgtcg gacagtcgtt tgagaacaac agaagcaata ccctcgccgc
    21961 gggcatatcc attagctcca gcgtcccaca tacggccgcg cccatcaggg gatgacatgg
    22021 tcatttttgt gataacgata tagaatgagg gactgagtat tagattcgta ccggccgcaa
    22081 tagcaacggg acactcgtgc tgctggagag ccactactgc ctgttgaaga gcaaccatgc
    22141 tagacgagca ggcagtgtcg actaccaatg atgggccatg ccagtcgaaa aagtaagaca
    22201 ctcggtttgc gaggatgctg cgcgctgagc ccgttgccgc gtggcttgga acggattgat
    22261 ggtctgttgc aaagaagtcg ggccaatccg tccccatttg gccacagaat actccggtag
    22321 atgaaccctt gagctggtct atgcgctgac cagcagcttc cagagactca aatacagtct
    22381 caagcagttg tcgttgttgc gggtcgatcg aggccgcctc ggtagaggag atgttaaaga
    22441 aggcggcatc gaaatagcgt gggtcctctg taaggaagta gccctccttc gcgttcaatg
    22501 tccccgggta tgtgggatcc tcatggtaaa aggaagaggc atcccatcga ctggcagggg
    22561 gcactgacgc gacatcgcgg ggctccttga gcagatccca aagacgagaa ggggtggtag
    22621 actgccctgg gaatcggcag ctggttccga taatagcaat gggctcagct gtcatgacgc
    22681 tggagacgaa aggcaagaga cggtgtggat caatgaactt gtaaggcgca atcgagagta
    22741 gaaacagtag tagtgatcga gcagtagcgt accatgaacc ctgggagatc ttccaatgat
    22801 aagacagcgc ggacactgct cctcatgtat ttctacagtg gaatttccga ccatcggcga
    22861 accgcacgca gacacattca gtgatttggc gaggccgggg aactcaatac ctcgccgacg
    22921 caaggatcga gatccctcga ggagcaaaga ccgaagcagg tacgcacgaa gaccaaaacg
    22981 gttcccttca agcaggccgg attataattt cagcgttgac ctgcatcaag gccgtattat
    23041 accccctgct ctccatccat ggccttgagt atacgacatc aggccgtgcg taacgggaat
    23101 ggcctgcttt cggatcttcc aatgccgacc tactaggaat attctccagg gggctcgctg
    23161 tccgtcaatt taaggatgac aatgtgggtt tccagttgaa tcccccaaca ttccactgaa
    23221 tcaagactga ttcattttcg accttctcgt gggcatcatg agcatttcca gcaaagattc
    23281 aggcctgcgt atcattatca ttgggggggg catcactggc cttgcactcg cccattttct
    23341 ggagcacgca ggcattaact ttgtcctgtt ggagaagcac cacgatatcc tagcgaattt
    23401 cggaggctca gtcggcctac aggcaaatgg ctgtcgtatc ctcgaacagg ttggagtcta
    23461 cgagcacctg gagcaatgga tgacagccac ggaattcatt agggcacgtc ttcctgatgg
    23521 ttttacatgg gtataccctt cccatttgta tacatcaatg taatggcttt atgaaaatcc
    23581 tcctttctta tggaacaaca ctaactcaat catgccaggc ttggatatcc gctctttatg
    23641 ataagacgca ccgttcttct ccgatgtctc tacgatagcc tgaaggacca atccaaaatt
    23701 aaggtcggtt cgaaggttct ttccatcact cgcaccggct gttcagacgg gcccttatct
    23761 gtcacgaccg ctgaaggagc ccagtatacc ggggatattg tcgttggcgc cgacggagtc
    23821 catggcatca ctcgtgccga gatgtggcgg ctggccgagc cccaactttc tgaaccaagt
    23881 cctgaacata tgactgtcga ctacatgtgt atccttggga tcacccagcc ggtcgaatcc
    23941 ttggccgaga tgatcaggat gaacggaatt tatggcactt tctacaagca cgttgtctgg
    24001 attgtcattc caaacaagga caacagcgtc aattggtctg ctcttatcaa gctcgacagg
    24061 acttatgctc atccaaatgt gcccaaatgg tctcaggagg aagtgatgac aagattggag
    24121 gccttggaag agcataccct agatggcact ctcaagttcc gggctttttg ggagataact
    24181 gaatccatct cgtctgttcc gatatatgag gggatagttc agaccacaac tctcggccgc
    24241 attgtttgca ttggtgataa tgtgttcaaa gtaagcattc tcctgctttc ccttaccatg
    24301 ccctgggctc ctggtaacat cgatctagat gtcgccttac cttgctgagg gtggtaatct
    24361 gtgtctggaa agcgcagcca ttcttgccaa cactctgcgc cgactgaaca cgccgcaaac
    24421 caaacacaca gaagcggaga taagcgctgg gctgagagat tccacagcag cacacatggc
    24481 caggcttcgg cgaaggtgcg ccgagtccta tgtgctcgca cgcacaatag ccctggaaac
    24541 ttggactggc tggttctggt tgcgctattt cgcgaagtac actgcaacct ctgcatgcta
    24601 ttacatcatg accttccagg atgccggtcc tacgttggac tatcttccaa tgccaactcg
    24661 agcgagactt gcctccaagc gcctggaaca aatggtgaaa aagcggagaa gaactgcgtg
    24721 gctatcgtgc ggagttgcct ttggagtgat atccttgtcc ttcttgtggt tcctctcctg
    24781 atgctgtggg tcatttcgtc gaaaattccc tgagggattg ttccctatac cgatacatcc
    24841 cattctagca atacgtgcat ttaaatctaa atacattcaa atgaatgagt ttgacaaggc
    24901 ccgacaacgt cagctacgta atctcttcct tcgtgcttta tgattaagac tctcatacat
    24961 gactgcatca gcaatgccaa gcaggcccaa tcgccaggtc
//
