BGC0002259: beauveriolide I biosynthetic gene cluster from Cordyceps militaris CM01
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Location: 4,116,198 - 4,146,740 nt. (total: 30,543 nt).
This entry is originally from NCBI GenBank JH126399.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002259
Short description beauveriolide I biosynthetic gene cluster from Cordyceps militaris CM01
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
  • NRPS (Type I)
Loci
JH126399.1
4116198 - 4146740
via Heterologous expression
Compounds
  • beauveriolide I
  • beauveriolide III
Species Cordyceps militaris CM01 [taxonomy]
References
Chemical products information
beauveriolide I Evidence:
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Chemical database entries
NPAtlas
beauveriolide III Evidence:
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Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • CCM_01282
  • EGX96624.1
 4117047 - 4125452 (-) polyketide synthase, putative
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    • CCM_01283
    • EGX96625.1
    		 4126586 - 4128043 (+) Transferase
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      • CCM_01284
      • EGX96626.1
      		 4128455 - 4131193 (-) AMP dependent CoA ligase, putative
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        • CCM_01285
        • EGX96627.1
        		 4131512 - 4145862 (+) non-ribosomal peptide synthase, putative
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          Biosynthesis information

          Biosynthetic modules

          Name
          Unk01
          Type
          nrps-type1
          Genes
          CCM_01285
          Substrates
          phenylalanine (evidence: Structure-based inference [1])
          Integrated Monomers
          Domains
          adenylation
          Name
          Unk02
          Type
          nrps-type1
          Genes
          CCM_01285
          Substrates
          alanine (evidence: Structure-based inference [1])
          Integrated Monomers
          Domains
          adenylation
          Name
          Unk03
          Type
          nrps-type1
          Genes
          CCM_01285
          Substrates
          leucine, isoleucine (evidence: Structure-based inference [1])
          Integrated Monomers
          Domains
          adenylation
          Annotation changelog

          Entry version: 1

          Date
          Changes
          Submitters
          Reviewers
          2022-09-15
          Entry added
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          2022-09-15
          Added NRP substrate specificities
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          Detailed domain annotation
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