BGC0002273: butyrolactone III biosynthetic gene cluster from Aspergillus terreus NIH2624
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Location: 104,608 - 145,729 nt. (total: 41,122 nt).
This entry is originally from NCBI GenBank CH476597.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002273
Short description butyrolactone III biosynthetic gene cluster from Aspergillus terreus NIH2624
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
CH476597.1
104608 - 145729
via Knock-out studies
Compounds
  • butyrolactone III
  • butyrolactone I
Species Aspergillus terreus NIH2624 [taxonomy]
References
Chemical products information
butyrolactone III Evidence:
(no structure information available)
butyrolactone I Evidence:
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Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ATEG_02815
  • EAU36089.1
 104608 - 107521 (-) predicted protein
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    • ATEG_02816
    • EAU36090.1
    		 107905 - 108736 (+) predicted protein
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      • ATEG_02817
      • EAU36091.1
      		 109630 - 110498 (-) predicted protein
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        • ATEG_02818
        • EAU36092.1
        		 112088 - 113579 (-) predicted protein
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          • ATEG_02819
          • EAU36093.1
          		 114179 - 115624 (-) predicted protein
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            • ATEG_02820
            • EAU36094.1
            		 116634 - 118007 (+) predicted protein
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              • ATEG_02821
              • EAU36095.1
              		 118857 - 119654 (+) predicted protein
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                • ATEG_02822
                • EAU36096.1
                		 120173 - 121219 (-) predicted protein
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                  • ATEG_02823
                  • EAU36097.1
                  		 121853 - 123178 (-) predicted protein
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                    • ATEG_02824
                    • EAU36098.1
                    		 123796 - 124908 (-) conserved hypothetical protein
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                      • ATEG_02825
                      • EAU36099.1
                      		 125541 - 127502 (+) predicted protein
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                        • ATEG_02826
                        • EAU36100.1
                        		 128010 - 128581 (-) predicted protein
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                          • ATEG_02827
                          • EAU36101.1
                          		 129550 - 130431 (-) predicted protein
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                            • ATEG_02828
                            • EAU36102.1
                            		 131536 - 132878 (-) predicted protein
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                              • ATEG_02829
                              • EAU36103.1
                              		 133767 - 135113 (-) predicted protein
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                                • ATEG_02830
                                • EAU36104.1
                                		 135821 - 138207 (-) predicted protein
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                                  • ATEG_02831
                                  • EAU36105.1
                                  		 138981 - 142865 (+) predicted protein
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                                    • ATEG_02832
                                    • EAU36106.1
                                    		 143284 - 143752 (-) conserved hypothetical protein
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                                      • ATEG_02833
                                      • EAU36107.1
                                      		 144581 - 145729 (+) predicted protein
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                                        Biosynthesis information

                                        Biosynthetic modules

                                        Name
                                        Unk01
                                        Type
                                        nrps-type1
                                        Genes
                                        ATEG_02815
                                        Substrates
                                        4-hydroxyphenylpyruvic acid (evidence: Structure-based inference [2])
                                        Integrated Monomers
                                        Domains
                                        adenylation
                                        Annotation changelog

                                        Entry version: next

                                        Date
                                        Changes
                                        Submitters
                                        Reviewers
                                        2024-07-23
                                        MIBiG v4 annotathon
                                        • (ID: 4CEPXXFDQQ46VQJXBT4B4AUO)
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                        Entry version: 1

                                        Date
                                        Changes
                                        Submitters
                                        Reviewers
                                        2022-09-15
                                        Entry added
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                        2022-09-15
                                        Added NRP substrate specificities
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                        Detailed domain annotation
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