LOCUS       BGC0002276              3813 bp    DNA     linear   CON 21-MAR-2015
DEFINITION  Aspergillus nidulans FGSC A4 chromosome V scaffold_6, whole genome
            shotgun sequence.
ACCESSION   BGC0002276
VERSION     BGC0002276
KEYWORDS    .
SOURCE      Aspergillus nidulans FGSC A4
  ORGANISM  Aspergillus nidulans FGSC A4
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus; Aspergillus subgen. Nidulantes.
COMMENT     ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2024-10-17 17:14:36
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 718081
            Orig. end    :: 721894
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     gene            1..3813
                     /locus_tag="AN5318.2"
     subregion       1..3813
                     /aStool="mibig"
                     /contig_edge="False"
                     /label="NRPS"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..3813
                     /contig_edge="False"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     CDS             1..3813
                     /NRPS_PKS="Domain: AMP-binding (13-413). E-value: 1.5e-82.
                     Score: 269.2. Matches aSDomain:
                     nrpspksdomains_AN5318.2_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (535-595). E-value: 1.7e-14.
                     Score: 46.0. Matches aSDomain:
                     nrpspksdomains_AN5318.2_PP-binding.1"
                     /NRPS_PKS="Domain: TD (644-890). E-value: 7.4e-76. Score:
                     246.4. Matches aSDomain: nrpspksdomains_AN5318.2_TD.1"
                     /NRPS_PKS="Domain: PKS_KR (1030-1197). E-value: 1.5e-15.
                     Score: 49.4. Matches aSDomain:
                     nrpspksdomains_AN5318.2_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: NAD_binding_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     293.9; E-value: 3e-89)"
                     /gene_kind="biosynthetic"
                     /locus_tag="AN5318.2"
                     /product="hypothetical protein"
                     /protein_id="EAA62478.1"
                     /sec_met_domain="AMP-binding (E-value: 1.5e-90, bitscore:
                     289.8, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3e-16, bitscore:
                     46.0, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 7.5e-68, bitscore:
                     214.4, seeds: 102, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 1.7e-10, bitscore:
                     26.6, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 1.1e-38, bitscore:
                     119.2, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAIIDTTKDLSALFTQQVRASPNALALEDDKTSYTYAELDKEVEE
                     LSRRLRSYGVSRDSLVGVLLPRSAHFVIACLAALRAGGAFLVLELAYPPDLLADVLEDA
                     TPAVVVTHRSETGKIKGSVPVISLDEPPVDANGHTVEPGPLPVDDDLDRLAFVSYSSGT
                     TGKPKGIANPHRAPVLSYNLRFGVQDLQPGDRVACNVFFIWEILRPLIRGATVVAVPDD
                     HSYDPAALVDLLASRHITETLMTPTLLATILSRHSDIGARLPELRTLWLNGEVVTTDLA
                     RRAIRALPNTRLLNCYSACETHEIACGDIKEIVSDESQYCPVGPLLDPKHAYIVNEQGE
                     KVEEGVSGELCVGGPMLARGYINRPETTAKAFIPDPFSNSPGAVMYRTGDRARMLPSGL
                     LEITGRVGAMIKLRGYSVVPGKVENDIVKHLAVRQCAVVAHGEGLERQLVAYIVADQEH
                     SEERPTVEINSSGHSPGARRALTKFLAHYMIPALWVQVDELPTHEVSGKIDLKRLPPPP
                     TEVLANGNGKKEDPIGIEDIAAIWAVALKVPKATLKPEDNFFDLGGHSLSIADLSSRLS
                     RKFGFRIPIVRLAENSTLSGHLDTVRAIRDGHTAAVQADLPAVLRTDATLDEEIRSDAK
                     ICSLTDAKTVLLTGVTGFLGAFLLKDLVDSTSAHIICLVRFNEPEDDDQPGGVARIRRN
                     LLDLGLWNDSIMERVEILPGNLSRSRFGLTPDAFQELAQRVDVIVHAAASVNLVYPYAA
                     LRAANVGGTREILRLASQGGATVQYVSTNGVLPPSGEKGWPEDTMLDMKDVPTKLLDGY
                     GQTKWVAEQLVLEAGRRGLPVRVHRIGTVSGHSQSGAANAWDLLTALIVESIKLGKYPD
                     VEGWRAEMTPVDFVSKAIIHLANQTAVEQTVFHIGDPDPVNTRSVFEDLKTLGYPTEPL
                     SWDDWVALWTSQRGHVKGGDGGFTVDILRSGMPSIEFLRGIVVLDNSATRPIRREVERP
                     KVDRFLLETYTRHWFARGWLKRPPIRQRQLSPIPKGPLSGKVAVVTGASSGIGAAVATA
                     LAREGAHVALGARRLDALESLKEKLSASGVKVVTCKTDVTDRKQVEGLVKAATEELGPV
                     DILVACAGVMYFTMMANTQMDEWERTVDVNCKGILNSLASTVPGMLARGKGHVVAISSD
                     AGRKVFPGLGVYSASKFFVEATLQALRLETAGQGLRVTAVQPGNTATDLLGMSTDAEAI
                     KKYGEPSGAQILDPEDVANSIIYALRQPEHVAMNEILIEPRDEPI"
     aSDomain        40..1239
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AN5318.2_AMP-binding.1"
                     /evalue="1.50E-82"
                     /label="AN5318.2_AMP-binding.1"
                     /locus_tag="AN5318.2"
                     /protein_end="413"
                     /protein_start="13"
                     /score="269.2"
                     /tool="antismash"
                     /translation="FTQQVRASPNALALEDDKTSYTYAELDKEVEELSRRLRSYGVSRD
                     SLVGVLLPRSAHFVIACLAALRAGGAFLVLELAYPPDLLADVLEDATPAVVVTHRSETG
                     KIKGSVPVISLDEPPVDANGHTVEPGPLPVDDDLDRLAFVSYSSGTTGKPKGIANPHRA
                     PVLSYNLRFGVQDLQPGDRVACNVFFIWEILRPLIRGATVVAVPDDHSYDPAALVDLLA
                     SRHITETLMTPTLLATILSRHSDIGARLPELRTLWLNGEVVTTDLARRAIRALPNTRLL
                     NCYSACETHEIACGDIKEIVSDESQYCPVGPLLDPKHAYIVNEQGEKVEEGVSGELCVG
                     GPMLARGYINRPETTAKAFIPDPFSNSPGAVMYRTGDRARMLPSGLLEITGRVGAMIKL
                     R"
     aSModule        40..2670
                     /complete
                     /domains="nrpspksdomains_AN5318.2_AMP-binding.1"
                     /domains="nrpspksdomains_AN5318.2_PP-binding.1"
                     /domains="nrpspksdomains_AN5318.2_TD.1"
                     /final_module
                     /locus_tags="AN5318.2"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       325..366
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AN5318.2_0001"
                     /evalue="7.80E+01"
                     /label="NRPS-A_a3"
                     /locus_tag="AN5318.2"
                     /protein_end="122"
                     /protein_start="108"
                     /score="-2.6"
                     /tool="antismash"
                     /translation="VVTHRSETGKIKGS"
     CDS_motif       463..522
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AN5318.2_0002"
                     /evalue="5.00E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="AN5318.2"
                     /protein_end="174"
                     /protein_start="154"
                     /score="19.1"
                     /tool="antismash"
                     /translation="AFVSYSSGTTGKPKGIANPH"
     CDS_motif       1033..1116
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AN5318.2_0003"
                     /evalue="3.00E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="AN5318.2"
                     /protein_end="372"
                     /protein_start="344"
                     /score="45.1"
                     /tool="antismash"
                     /translation="GVSGELCVGGPMLARGYINRPETTAKAF"
     aSDomain        1606..1785
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AN5318.2_PP-binding.1"
                     /evalue="1.70E-14"
                     /label="AN5318.2_PP-binding.1"
                     /locus_tag="AN5318.2"
                     /protein_end="595"
                     /protein_start="535"
                     /score="46.0"
                     /tool="antismash"
                     /translation="DIAAIWAVALKVPKATLKPEDNFFDLGGHSLSIADLSSRLSRKFG
                     FRIPIVRLAENSTLS"
     CDS_motif       1930..2019
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AN5318.2_0004"
                     /evalue="5.90E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="AN5318.2"
                     /protein_end="673"
                     /protein_start="643"
                     /score="9.3"
                     /tool="antismash"
                     /translation="TVLLTGVTGFLGAFLLKDLVDSTSAHIICL"
     aSDomain        1933..2670
                     /aSDomain="TD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AN5318.2_TD.1"
                     /evalue="7.40E-76"
                     /label="AN5318.2_TD.1"
                     /locus_tag="AN5318.2"
                     /protein_end="890"
                     /protein_start="644"
                     /score="246.4"
                     /tool="antismash"
                     /translation="VLLTGVTGFLGAFLLKDLVDSTSAHIICLVRFNEPEDDDQPGGVA
                     RIRRNLLDLGLWNDSIMERVEILPGNLSRSRFGLTPDAFQELAQRVDVIVHAAASVNLV
                     YPYAALRAANVGGTREILRLASQGGATVQYVSTNGVLPPSGEKGWPEDTMLDMKDVPTK
                     LLDGYGQTKWVAEQLVLEAGRRGLPVRVHRIGTVSGHSQSGAANAWDLLTALIVESIKL
                     GKYPDVEGWRAEMTPVDFVSKAII"
     aSDomain        3091..3591
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AN5318.2_PKS_KR.1"
                     /evalue="1.50E-15"
                     /label="AN5318.2_PKS_KR.1"
                     /locus_tag="AN5318.2"
                     /protein_end="1197"
                     /protein_start="1030"
                     /score="49.4"
                     /tool="antismash"
                     /translation="VAVVTGASSGIGAAVATALAREGAHVALGARRLDALESLKEKLSA
                     SGVKVVTCKTDVTDRKQVEGLVKAATEELGPVDILVACAGVMYFTMMANTQMDEWERTV
                     DVNCKGILNSLASTVPGMLARGKGHVVAISSDAGRKVFPGLGVYSASKFFVEATLQALR
                     LETA"
     CDS_motif       3097..3183
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AN5318.2_0005"
                     /evalue="3.30E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="AN5318.2"
                     /protein_end="1061"
                     /protein_start="1032"
                     /score="10.1"
                     /tool="antismash"
                     /translation="VVTGASSGIGAAVATALAREGAHVALGAR"
ORIGIN
        1 atggccatca ttgacaccac aaaagacctt tcggcccttt tcacccagca ggtccgtgcg
       61 agtcccaacg ccctcgctct ggaggatgac aaaacctcat acacctatgc agagctagat
      121 aaagaagttg aggaactgtc gcggcgactg cgcagctatg gcgtcagtcg ggacagtctc
      181 gttggtgtgt tactcccccg cagtgctcat ttcgtcattg cctgcttggc ggcgctgcgg
      241 gcggggggag cgttcctcgt cttggagctg gcgtaccccc cagatctgct tgccgacgtg
      301 ctcgaagatg ccactccagc agtagtggtc acgcaccggt cagagaccgg taagattaag
      361 ggcagcgtcc ccgtcatcag tctcgacgag ccccctgtcg acgccaatgg ccatactgtt
      421 gagcccggcc cgttaccggt tgacgatgac ttggaccggc tggctttcgt ctcgtactcg
      481 tccggcacta ccggtaaacc aaaaggaatt gcaaaccctc accgagctcc tgttctctca
      541 tataacctgc gtttcggcgt ccaggatctt caaccgggcg atcgcgtggc ttgtaatgtc
      601 ttcttcatct gggaaatcct gcgtcccttg atccgcggtg cgacggtggt cgccgtccca
      661 gatgaccaca gctatgaccc ggcggcactt gtcgatcttc ttgcctcgag gcatatcacc
      721 gaaacactca tgaccccgac tctccttgcc actatcctct ctcgacactc tgatatcgga
      781 gctcgattac cggaactgcg tacgttgtgg ctaaacggcg aggtcgttac tactgatcta
      841 gcgcgacggg cgattagggc actccctaac acccgactgc tcaattgtta tagcgcatgc
      901 gaaacccatg agattgcgtg cggtgatatc aaagaaatcg taagcgacga atcccagtac
      961 tgcccagtag gtcctctgct cgaccccaaa cacgcctaca ttgtcaacga gcagggcgag
     1021 aaggtagagg agggagtttc tggtgaactc tgcgttggcg ggcccatgct tgcaagaggg
     1081 tatatcaacc gcccagagac gaccgccaag gcatttattc ccgatccgtt ttcaaattct
     1141 ccaggagctg tcatgtaccg cactggagac cgggcgcgta tgttgccgtc gggtcttctt
     1201 gagatcactg gtcgcgttgg tgcaatgatc aagctgcgcg gatattccgt agtcccgggc
     1261 aaggtcgaga atgatattgt caagcacctc gcggtccgac agtgtgccgt cgttgcacac
     1321 ggggagggct tggaaaggca gctggtggca tacattgttg ccgaccagga acactctgag
     1381 gagcgtccaa ccgtggagat taactcctcc ggccacagcc caggtgcccg aagagccctg
     1441 accaaattcc tcgctcacta tatgattccc gccctatggg tgcaggttga tgaactgcct
     1501 acccacgagg tgtccggaaa gattgatctc aaacgccttc ctccgccccc gaccgaagtc
     1561 ctcgccaacg ggaacggaaa gaaggaagat cccatcggca ttgaggacat tgcagcaatc
     1621 tgggcggtcg cgctcaaggt tcccaaagcg acgcttaagc ctgaagacaa cttctttgat
     1681 ctcggtggtc actcgctttc gattgcggac ctctcttcta ggctgtcgcg gaaattcggt
     1741 ttccgcatcc ccatcgtacg cctggcagaa aattcaacgc tgagcggtca tttggatacc
     1801 gtgcgagcga tccgagacgg ccacactgct gctgtgcagg cagatttacc agcagttctt
     1861 cgcacagatg ccacacttga cgaagaaatt cgttcagacg cgaagatatg ctccctcaca
     1921 gacgccaaga cagttctgct gaccggtgtg actggctttc tcggtgcatt ccttctcaag
     1981 gacctcgttg acagcacatc tgcacacatc atctgtctcg tgagattcaa cgagcctgag
     2041 gacgatgacc agccgggtgg tgttgcgcga attcgccgca acctccttga ccttggtctt
     2101 tggaatgact ccataatgga gcgtgtcgag atccttccag gaaatctttc ccgttcgagg
     2161 tttggcctca cgcccgacgc attccaggaa ctggcgcaac gtgtcgacgt tattgtccat
     2221 gctgcggcct cagtcaacct ggtctacccg tacgcagccc tgcgcgctgc gaacgtgggt
     2281 ggcactcgcg aaatcctccg cctggcgagc caaggcggcg cgaccgtgca gtatgtgtcg
     2341 accaacggtg tcttgccccc ttctggggag aaagggtggc cggaggacac aatgttggac
     2401 atgaaggacg tgccaacaaa gctgctggat gggtacggac aaactaagtg ggtagcagaa
     2461 cagcttgtcc ttgaggccgg tcgtcggggt ctccctgtaa gggttcaccg catcggcaca
     2521 gtcagcggtc acagtcagtc aggtgctgca aatgcctggg atcttctcac tgctttgatc
     2581 gtggagtcga tcaaattggg caaataccct gatgttgagg gctggcgcgc ggaaatgact
     2641 ccagtggact ttgttagcaa agctattatc cacctcgcga atcagactgc agtggaacag
     2701 actgttttcc atatcggaga ccctgatcca gtgaacaccc gatctgtctt cgaggacttg
     2761 aagacactcg gttaccccac tgagccgctt tcctgggacg actgggtagc gctctggacg
     2821 agccagcggg gtcacgtcaa aggtggcgat ggtggcttta cagttgatat ccttcgcagc
     2881 ggtatgccat caatcgagtt ccttcgcggc atcgtggtcc tagacaactc tgccactcgt
     2941 cccatccgtc gggaagtaga gcggccaaag gtagaccggt tcctccttga gacatacacc
     3001 cggcattggt ttgcccgagg atggctgaaa aggccgccta ttcggcagcg gcagctcagc
     3061 cctatcccca agggtcctct tagcggcaaa gtagcagtcg ttactggcgc ttcgtctggt
     3121 atcggagctg cggtcgcgac ggctctggcc agagaaggcg cccatgtcgc tctcggtgcc
     3181 cgccgtttag atgcattgga atccctgaaa gagaagctct ctgctagcgg cgtcaaggtt
     3241 gtcacttgca agaccgatgt tactgacagg aagcaggtcg agggtctcgt gaaggcagca
     3301 accgaggagc taggtccagt ggacatcctc gtggcttgcg ctggcgtaat gtactttaca
     3361 atgatggcca atacccaaat ggacgagtgg gagcggacag tcgatgtgaa ctgcaagggt
     3421 attctcaact ctcttgcatc tactgtaccc ggaatgctgg cgcgcggtaa gggtcacgtt
     3481 gtggcgattt cttcagacgc cggtcgcaag gtctttccag gactgggagt atattcggcc
     3541 agtaagttct tcgttgaggc aacccttcag gcactgcgtt tggagacggc cggtcaaggc
     3601 ttgcgggtaa cagccgtaca acctggaaac acagccaccg acctcctggg catgtcaacc
     3661 gatgcagagg ccatcaagaa gtacggcgag ccatccgggg cacagatctt ggaccccgag
     3721 gatgttgcca actccattat ctacgctctc cgccagcctg aacatgttgc catgaacgag
     3781 atcctgattg agccgcgaga cgagccaatc tag
//
