BGC0002277 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002277 (Suillus grevillei)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS-like	1	3,145	atromentin	NRPS:Type I	100%

BGC0002277 - Region 1 - NRPS-like

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Location: 1 - 3,145 nt. (total: 3,145 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 3,146
Label		BGC0002277

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002277	1.00	NRP	atromentin	Suillus grevillei
BGC0002274	0.34	NRP	aspulvinone H, aspulvinone B1	Aspergillus terreus NIH2624
BGC0002348	0.33	NRP	aspulvinone E	Aspergillus terreus NIH2624
BGC0002193	0.33	Other	phenguignardic acid	Aspergillus terreus NIH2624
BGC0001668	0.23	NRP	microperfuranone	Aspergillus nidulans FGSC A4
BGC0000442	0.22	NRP	terrequinone A	Aspergillus nidulans FGSC A4
BGC0002271	0.21	NRP	asterriquinone CT5	Aspergillus terreus NIH2624
BGC0001712	0.16	Other	ochrindole A	Aspergillus steynii IBT 23096
BGC0001834	0.08	NRP	argyrin	Cystobacter sp. SBCb004
BGC0000427	0.08	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002277	1.00	NRP	atromentin	Suillus grevillei
BGC0002274	0.67	NRP	aspulvinone H, aspulvinone B1	Aspergillus terreus NIH2624
BGC0002348	0.66	NRP	aspulvinone E	Aspergillus terreus NIH2624
BGC0002193	0.66	Other	phenguignardic acid	Aspergillus terreus NIH2624
BGC0001668	0.57	NRP	microperfuranone	Aspergillus nidulans FGSC A4
BGC0000442	0.55	NRP	terrequinone A	Aspergillus nidulans FGSC A4
BGC0002271	0.54	NRP	asterriquinone CT5	Aspergillus terreus NIH2624
BGC0001712	0.47	Other	ochrindole A	Aspergillus steynii IBT 23096
BGC0001834	0.30	NRP	argyrin	Cystobacter sp. SBCb004
BGC0000427	0.30	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 3145:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

greA

AMP-binding (61..465): X

nrpys: 4-ohPpa

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic (Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr)
Large clusters prediction:: Aromatic side chain (Phe, Trp, Ph-Gly, Tyr, bOH-Tyr)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: VALFNGGAGK
Nearest Stachelhaus code(s):: 4-ohPpa VALFNGGAGK (100% 8Å match)
Stachelhaus code match:: 100% (strong)