BGC0002289: Leepeptin biosynthetic gene cluster from Streptomyces leeuwenhoekii
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 648,370 - 654,833 nt. (total: 6,464 nt).
This entry is originally from NCBI GenBank LN831790.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002289
Short description Leepeptin biosynthetic gene cluster from Streptomyces leeuwenhoekii
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • ribosomal (RiPP)
Loci
LN831790.1
648370 - 654833
via Heterologous expression
Compounds
  • Leepeptin
Species Streptomyces leeuwenhoekii [taxonomy]
References
Chemical products information
Leepeptin [synonyms: leepeptin, LP2] Evidence: NMR [2], Mass spectrometry [2], MS/MS [2]
Copy SMILES
C110H143N27O31
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • CQR60039.1
  • sle_05770__ls2E
 648373 - 650154 (-) Lactococcin transport/processing ATP-binding protein LcnC-like
    copy AA seq
    copy Nt seq
    • CQR60040.1
    • sle_05780__ls2E
    		 650151 - 651911 (-) Uncharacterized ABC transporter ATP-binding protein YfiC
      copy AA seq
      copy Nt seq
      • CQR60041.1
      • sle_05790__ls2A
      		 652020 - 652151 (-) precursor
        copy AA seq
        copy Nt seq
        • CQR60042.1
        • sle_05791__ls2D
        		 652180 - 652635 (-) protease
          copy AA seq
          copy Nt seq
          • CQR60043.1
          • sle_05800__ls2C
          		 652692 - 652949 (-) Conserved Hypothetical Protein
            copy AA seq
            copy Nt seq
            • CQR60044.1
            • sle_05810__ls2B
            		 652953 - 654830 (-) Asparagine Synthase
              copy AA seq
              copy Nt seq
              Biosynthesis information
              Annotation changelog

              Entry version: next

              Date
              Changes
              Submitters
              Reviewers
              2024-04-23
              MIBiG v4 annotathon
              • (ID: G42B4RI57WLTDHDCD4PMU3MJ)
              • (ID: XNMHANLE2XI45CDKHGNZCRRK)
              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

              Entry version: 1

              Date
              Changes
              Submitters
              Reviewers
              2022-09-15
              Entry added
              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
              Similar known gene clusters from MIBiG 4.0
              Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
              Click on reference genes to show details of similarities to genes within the current region.
              Click on an accession to open that entry in the MiBIG database.