BGC0002293 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002293 (Streptomyces sp)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS	1	56,950	ohmyungsamycin A/ohmyungsamycin B	NRPS:Type I	100%

BGC0002293 - Region 1 - NRPS

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Location: 1 - 56,950 nt. (total: 56,950 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 56,951
Label		BGC0002293

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002293	1.00	NRP	ohmyungsamycin A, ohmyungsamycin B	Streptomyces sp.
BGC0001844	0.34	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0001758	0.34	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0000844	0.34	Other	clavulanic acid	Streptomyces clavuligerus
BGC0001131	0.33	NRP	ambactin	Xenorhabdus miraniensis
BGC0001833	0.32	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001582	0.32	NRP	ecumicin	Nonomuraea sp. MJM5123
BGC0000307	0.31	NRP	AbT1	Aureobasidium pullulans
BGC0002286	0.30	NRP	ririwpeptide A, ririwpeptide B, ririwpeptide C	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001135	0.30	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002293	1.00	NRP	ohmyungsamycin A, ohmyungsamycin B	Streptomyces sp.
BGC0001844	0.67	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0001758	0.67	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0000844	0.67	Other	clavulanic acid	Streptomyces clavuligerus
BGC0001131	0.66	NRP	ambactin	Xenorhabdus miraniensis
BGC0001833	0.65	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001582	0.65	NRP	ecumicin	Nonomuraea sp. MJM5123
BGC0000307	0.65	NRP	AbT1	Aureobasidium pullulans
BGC0002286	0.64	NRP	ririwpeptide A, ririwpeptide B, ririwpeptide C	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001135	0.64	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 56950:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (NMe-Val - Val - Thr - NMe-Thr - Val - NMe-Leu - Val - NMe-Val - NMe-X - Val - Phe - Val)

Direct lookup in NORINE database: strict or relaxed

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NRPS/PKS substrate predictions

ohmA

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AMP-binding (19..390): Val

nrpys: Val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: val (Val)