LOCUS       BGC0002294             30920 bp    DNA     linear   BCT 25-FEB-2019
DEFINITION  Streptomyces achromogenes subsp. streptozoticus strain NRRL 3125 RNA
            polymerase sigma factor SigA, ABC transporter ATP-binding protein,
            xylulose kinase, phosphoglyceromutase, ATP synthase subunit b,
            pentatricopeptide repeat-containing protein, ribonuclease, and
            tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase genes,
            complete cds; streptozocin biosynthetic gene cluster, complete
            sequence; and putative hydrolase, multidrug resistance protein,
            serine/threonine-protein kinase, and nitrate regulatory protein
            genes, complete cds.
ACCESSION   BGC0002294
VERSION     BGC0002294
KEYWORDS    .
SOURCE      Streptomyces achromogenes subsp. streptozoticus
  ORGANISM  Streptomyces achromogenes subsp. streptozoticus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 17:16:13
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..30920
                     /db_xref="taxon:285532"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces achromogenes subsp. streptozoticus"
                     /strain="NRRL 3125"
                     /sub_species="streptozoticus"
     subregion       1..30920
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0002294"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..30920
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     CDS             413..1573
                     /codon_start=1
                     /note="orf-9"
                     /product="RNA polymerase sigma factor SigA"
                     /protein_id="QBF29316.1"
                     /transl_table=11
                     /translation="MQTRTLAQTDSSTSATRTDPDEPDAETGVLVAVPPRDRAGDLDPE
                     PAAEEAEEAAGEAEGPDESEPDEPVEAEVPVVARAESGGPSADLFRQYLREIGRIPLLT
                     AAEEVELARRVEAGLFAEEKLGTTPDLDSELALDLDRLVVMGRMAKRRLIEANLRLVVS
                     VAKRYVGRGLTMLDLVQEGNLGLIRAVEKFDYARGYKFSTYATWWIRQAMSRALADQAR
                     TIRVPVHVVELINRVVRVQRRMLQERGHEPTAEEVGAHLDLSPERVREVLRLAQEPVSL
                     HAPVGEEDDVALGDLIEDGDAASPVESAAFLLLREHLDAVLSTLGERERKVVQLRYGLA
                     DGRPRTLEEIGRLFGVTRERIRQIESKTLSKLRDHTFAEQLRGYLD"
     CDS             complement(1604..3532)
                     /codon_start=1
                     /gene_functions="resistance (resist) ABC_efflux (Score:
                     320.6; E-value: 1.2e-97)"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 376.3; E-value:
                     4.6e-114)"
                     /gene_kind="transport"
                     /note="orf-8"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="QBF29317.1"
                     /transl_table=11
                     /translation="MAGPMGRMMAGGGPDQRSMDFKGSGKRLVARFRPERLTIYALLLC
                     VVVSVALSVVGPKILGRATDLVFSGIVGRQMPHGATKEQVLDSLRERGQGRVADMLKGT
                     DFTPGKGIDFTAVGEVLLLALGTFLVAGLLMAVATRLVNRAVNRTMYRMREDVQAKLSR
                     LPLSYFDKRQRGEVLSRATNDIDNIGQTLQQSMGQLINSVLTIVGVLVMMFWVSWILAL
                     VALVTVPLSFVVATRVGKRSQPHFVQQWRSTGTLNAHIEEMYTGHALVKVFGRQDESAQ
                     QFAEQNEALYQAGFKAQFNSGIMQPLMMFVSNLNYVLVAVVGGLRVASGALSIGDVQAF
                     IQYSRQFSMPLTQVASMANLVQSGVASAERIFELLDAEEQEADPVPGERPAELRGRVCL
                     EHVSFRYDPEKPLIEDLSLTVEPGHTVAIVGPTGAGKTTLVNLLMRFYDVSAGRITLDG
                     VDIRRMTRDELRAGIGMVLQDTWLFGGTIAENIAYGAAREVTRGEIEEAARAAHADRFI
                     RTLPDGYDTVIDDEGTGVSAGEKQLITIARAFLSDPVILVLDEATSSVDTRTEVLIQKA
                     MAKLASGRTSFVIAHRLSTIRDADTILVMENGSIVEQGAHAELLAASGAYARLYQAQFA
                     QAVAEVD"
     CDS             complement(3532..5319)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 362.7; E-value:
                     5.9e-110)"
                     /gene_kind="transport"
                     /note="orf-7"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="QBF29318.1"
                     /transl_table=11
                     /translation="MGAKGNRPAPVADPERRSVLIRLLRTYLRPYKKPIALLVVFQLLQ
                     TCATLYLPTLNADIIDNGVVKGDTGYILSFGVLMIGISLVQVVCNIGAVYYGARTASAL
                     GRDVRGAVFDRVQSFSAREVGHFGAPSLITRTTNDVQQVQTLALMTFTLMVSAPIMCVG
                     GIVLALGLDVPLSAVLVAVVPVLGVCVTLIVRRLRPLFRSMQVRLDTVNRVLREQITGN
                     RVIRAFVRDSYEQERFGRANAELTDMQLATGRLLALMFPMVMTVVNLSSIAVVWFGAHR
                     IDSGGMAIGDLTAFLAYLMQIVMSVMMATFMFMMVPRAEVCAERIQEVLDTESSVVPPA
                     APVARLRSHGHLEIRGAGFRYPGAEEPVLRSIDLTARPGETTAVIGSTGSGKSTLLGLV
                     PRLFDATDGEVLVGGVDVREADPVLLAKTVGLVPQKPYLFAGTVATNLRYGNPDATDEE
                     LWHALEVAQAKDFVTKLEGGLDAPIAQGGTNVSGGQRQRLAIARTLVQRPEIYLFDDSF
                     SALDYATDAALRAALARETAEATVVIVAQRVSTIRDADRIIVLDEGRVVGSGRHAELMA
                     ANQTYREIVLSQLTEAEAA"
     CDS             complement(5446..6867)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1210:glycerol kinase (Score: 306.1; E-value: 6.6e-93)"
                     /gene_kind="biosynthetic-additional"
                     /note="orf-6"
                     /product="xylulose kinase"
                     /protein_id="QBF29319.1"
                     /transl_table=11
                     /translation="MDSSPEFTRIVVCDTDTGAVLRQGYAPHPVEGRPSDVDPQIWLLS
                     LGEAAGGGLLEGVQAIGVSAQQNAVVPLDAQGNTVRPALVGGDKRAQVAAADLVDALGG
                     REAWAQAVGCVPGAAQPVTKLRWLAKNEPEHAQRTAVLLQAHDWLVWQLLGRPLRRTTD
                     RGGASGTGYWSAATGAWRPDLVELALGHQAVLPEVIGPSDAAGTTPEGLLISAGTGETM
                     AAAFGLGLGPGDVVVSLGASGSVTAVHPEALADQSGMITSLADATGMHLPVVTTLNAVR
                     ALRGTAELLGLPDLESLSELAVKSTPGAHGLVLLPYLEGERTPNLPHTAGTLAGLRRES
                     MKPEHLARAAFEGMLCGLADALDVLRGRGVEVRRIFLLGAAAELPAVQASAPSLFGAQV
                     VVPQPADYAAIGAARQAAWALGVSQGTLDPRTPPAWQGAAAQVLEPGEELALGQAVRQQ
                     FTAVREQTHPGAFRP"
     CDS             complement(6998..7291)
                     /codon_start=1
                     /note="orf-5"
                     /product="phosphoglyceromutase"
                     /protein_id="QBF29320.1"
                     /transl_table=11
                     /translation="MRYRLTFLAGLALGYVLGTKAGRERYEQLKKSAQQIAQNPAVRNT
                     AETAAQQGRVYAGKAFHTVGDRIPESVAHRVRSLRERNGHGTREDDWGTGTT"
     CDS             8185..8586
                     /codon_start=1
                     /note="orf-4"
                     /product="ATP synthase subunit b"
                     /protein_id="QBF29321.1"
                     /transl_table=11
                     /translation="MRTVREAGAGWSVGRRQRLLAECTVGGTADPAGWPPLSHALNRRP
                     DVRRASPVEPRRCQAPLAVAREAPAIQVRRCRLQAADGAERTAARGGEIGSAPRVSFRG
                     GAFGGQSSHAASHMRTAEIVGLPGLPLHG"
     CDS             8583..10277
                     /codon_start=1
                     /note="orf-3"
                     /product="pentatricopeptide repeat-containing protein"
                     /protein_id="QBF29322.1"
                     /transl_table=11
                     /translation="MNTGVARKTVGFDEDGLRALAGTRSFERGLGYLEAVSGLEVGDGS
                     VTAVVHGTDVYEVELTHGGDEGISGRCDCPYGQEGNFCKHCVAVGLTVLRRAKTIPHQR
                     AAARARASTLEGWLSALSRDELLALVREHVAEDRELRRRLELRAAAARSDLRTVRDRVV
                     ALIDPRPFARYGYIEYVDAAGYARQVAEAADALRALIAGRQAAQAVGLAEEALRALGEA
                     YGEIDDPDGVIGEAAAAMAKAHLEACGAARPDPDRLAESLVGHLLGDGSEVTDLDPLDY
                     AEVLGPSGLARMRQLATEALRRRPSGRAERYLMERLVKAGGDVDALVALHAQDLEPSGA
                     THLRIAEELEAAGRADEALAWAGRGLRDCAAETHVDGRLVEYVCVRYAKTGRAADAVAV
                     RRDRFRVERSLAAYRQLRSAARAADCWEAERAAALATLREDARREQGGRYGGPVLIDAL
                     IDDGDLDAAWREAAGRAGDRQWERLADLSRETRPGEALDVYLRLVERSTEPTGDRAYEH
                     LARLLQGVRDCHRALGTEEVFGAYLGGLRTELKRRRKLMSILERHGL"
     CDS             complement(10341..10547)
                     /codon_start=1
                     /note="orf-2"
                     /product="ribonuclease"
                     /protein_id="QBF29323.1"
                     /transl_table=11
                     /translation="MPDGVYRRARVVQELLTAKGEHRSAGPVDLLVAAAAEEAGLTLLH
                     HDRDVETIARTTGQPVRMIDLTN"
     CDS             10749..11285
                     /codon_start=1
                     /note="orf-1"
                     /product="tRNA-2-methylthio-N(6)-dimethylallyladenosine
                     synthase"
                     /protein_id="QBF29324.1"
                     /transl_table=11
                     /translation="MEGAASAGPERFCSAGRDVIAQAFLPKARINVLNRLTGADLDRLV
                     TNGLGEVALGIESGSDRILAATDKRIGAETTERVARRLVAHGIGVKGCFILGFPGETRS
                     DLDATVRHIRNRRNRDRRSHSGPPGPKKGSHQCHRAAAAHRAGAAPAPRTGCRTVFPDR
                     PCNPFPLPGVLSGNG"
     gene            11278..11871
                     /gene="stzA"
     CDS             11278..11871
                     /codon_start=1
                     /gene="stzA"
                     /gene_functions="regulatory (smcogs) SMCOG1032:RNA
                     polymerase, sigma-24 subunit, ECF subfamily (Score: 115.8;
                     E-value: 2.8e-35)"
                     /gene_kind="regulatory"
                     /product="RNA polymerase sigma-H factor"
                     /protein_id="QBF29325.1"
                     /transl_table=11
                     /translation="MDEKAERQLTELLAVDLDGGFTELVRVHGRAVYTFLLRVSGSATE
                     ADDLGQDVFLRAYTALQGYDSERRRQLSPRPWLLTVAANVWRNHLRTCSRRPALAGVPV
                     EDTADTWTDRSPGPEELAALAEDRRRLVLALLELPEHHRAPVVLRHVLGLSYTEVAEVQ
                     RCAVGTAKAQVSRGLKGLRRLLEPETALLEEVMT"
     misc_feature    11278..24994
                     /note="streptozocin biosynthetic gene cluster"
     gene            11868..12668
                     /gene="stzB"
     CDS             11868..12668
                     /codon_start=1
                     /gene="stzB"
                     /product="methylated-DNA--protein-cysteine
                     methyltransferase"
                     /protein_id="QBF29326.1"
                     /transl_table=11
                     /translation="MRSDREVPRLDAARPGLAGLVTEPPADFAARVLRRAGVPRERYDT
                     YVRLGTAAGGLYVAASPEAVTGAALDTGGLTAPGFEELHRSRTNRSALRSAKPFPGVTT
                     ALRTGRARRLPIDLSPLAPADRAVLEAVRAIPAGQLRPVGWIAREAAVDPAAVPGALAL
                     NPAAVLIPCHRVTYDNGTPCDAGYLPGAGEALRAAEGIEPGRVAELRRRGVVFLGSDTT
                     RIYCHPTCAHARRITPPHQVPFRTAREAGRAGYRACKSCRPLTA"
     gene            12727..13272
                     /gene="stzC"
     CDS             12727..13272
                     /codon_start=1
                     /gene="stzC"
                     /product="methylated-DNA--protein-cysteine
                     methyltransferase"
                     /protein_id="QBF29327.1"
                     /transl_table=11
                     /translation="MSTTHTTAVVTTHPTPLGPLVLGATADALVLCCYGAVDDAVARLT
                     RGGLRAVEEERADPAQLKVLAETRDQLDAYLTGARRDFTLPVDLRLATPFSRQTVMALD
                     AFVPYGRTATYAGLAEALGRPRAARAVGTALGANPVCVVLPCHRIVGSGGGLNGYAGGL
                     DAKRFLLALEAGDGPAAP"
     gene            13355..14122
                     /gene="stzD"
     CDS             13355..14122
                     /codon_start=1
                     /gene="stzD"
                     /product="proline hydroxylase"
                     /protein_id="QBF29328.1"
                     /transl_table=11
                     /translation="MNSYDTPPLPGLAEPAPAGRPAPDGGVLPPLDWTALAAELDAEGV
                     ALTPPLLDADQCARLREMYDEPALFRSTVTMARHRFGEGSYRYFAHPLPEPVAALRREL
                     YPPLARIANTWAARLGEPEFPDRHEDLVAACAAAGQHRPTPLLLRYGPGGYNCLHQDVY
                     GDLTFPLQVAVLLDRPDEDFTGGESVFVEQRPRAQSRPLVRRPVQGQGLIFTVHHRPVR
                     SARGWSRVQLRHGVSAVHSGRRHVLGVIFHDAR"
     gene            14472..15491
                     /gene="stzE"
     CDS             14472..15491
                     /codon_start=1
                     /gene="stzE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /product="protein arginine N-methyltransferase"
                     /protein_id="QBF29329.1"
                     /sec_met_domain="PCMT (E-value: 3.5e-08, bitscore: 24.2,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPANGSPYRLGAALLQSLAQEMNALAEQASALLSMPPESLSLDAD
                     AFAQIARRNVPRWHFAMLNDTERNTALMTALERGIPAGATVLDIGSGSGLLAMAAARAG
                     AGRVFTCEMNPLLAEIARNVISAHGMSDVITVIGKPSTALDPVRDLGGPVDVLVSEIVD
                     CGLIGEGLLPSVRHAREHLLKPDGIMLPSAARLHGRLVSSDEVLKLNQVTTAGGFDVSL
                     MNTVATRGHFPVRLDTWPHRFLSEAAPLVEFDLARSALEPGERPLALTATADGEVQALA
                     VWFELDMGSGITLSNPPDNPRSHWMQGWVPLDKPVPVKAGETLALRLGWSDFTLRVSI"
     gene            15562..16977
                     /gene="stzF"
     CDS             15562..16977
                     /codon_start=1
                     /gene="stzF"
                     /product="cupin domain-containing diiron protein"
                     /protein_id="QBF29330.1"
                     /transl_table=11
                     /translation="MSHVPPHVPFELSGAELRDAIVQYATNPIYHDNLDWLNHDNPYRR
                     QLRPQVLPHLDYDKVPGRENILNYASLAVQRLLTSVYEADLVFFPKSGLKGKEEDFRAF
                     YSPANRALGERIRPALERYAFGFLDDEVETSGTWTAQSLDAYLDSLDTAGGAEQSPVEK
                     AILGSADRERAARMWLVQFAPDFLSEASPMMRNVLGYYGPAQSEWFKVVIDEYGYGVHD
                     TKHSTLFERTLESVGLESDLHRYWQYYLNSSLLLNNYFHYLGKNHELFFRYVGALYYTE
                     SSLVDFCRRADHLLREVFGDTVDTTYFTEHIHIDQHHGRMAREKIIKPLVEAHGDGIIP
                     EIVRGIEEYRVLLEIGDFDFSEQIAWMDAQPELKKLHDPVFEGLKQGKVDAPVAHLVEP
                     RGELSNTHCHDGDELCHIVSGTMRFESGLGSSLTLQAGEGVVIKRNRLHGANIESDECV
                     YEIHSVGDYRKCL"
     gene            16977..17342
                     /gene="stzG"
     CDS             16977..17342
                     /codon_start=1
                     /gene="stzG"
                     /product="Rieske domain-containing protein"
                     /protein_id="QBF29331.1"
                     /transl_table=11
                     /translation="MTFSAEGRDNCVVIAGTPYVYATVGGRGFVMRARCPHRGGPLHLA
                     GVAEDGVRLVCPWHERKTSVARMRAEVPAVRVGGRVTAVFPERPAAGGWPAPPQDCAVG
                     LEHRPLAPALSRPSRAG"
     gene            17488..18738
                     /gene="stzH"
     CDS             17488..18738
                     /codon_start=1
                     /gene="stzH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1063:argininosuccinate lyase/adenylosuccinate lyase
                     (Score: 103.9; E-value: 1.7e-31)"
                     /gene_kind="biosynthetic-additional"
                     /product="argininosuccinate lyase"
                     /protein_id="QBF29332.1"
                     /sec_met_domain="ATP-grasp_3 (E-value: 2.1e-11, bitscore:
                     34.9, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 2.6e-07, bitscore:
                     21.2, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGRDGDKPLLLLIGSSSRRSREFILRSVSRRYALWLLQPAPVTWE
                     EPYVVGSTQVDNTRPELLVEAARQVAAEHEVTGVFCYDEGLVTPAAHVSEALGLPGNSP
                     ETVIACRDKNATRTALERAGVAQPASIGVRSLAEAQAAADKIGFPVVLKPRGLAGGMGV
                     RRADGPDEVDSAYRAATGVTYPGVPVFEVSVLVEEYVDGPEISVDAVFFEGEGTPLAVA
                     RKQVGLAPFFEETGHEVDAADPLLSDPRLLEALRASHAALGFHTGVSHTEFRLTADGPR
                     LMEVNARLGGDMIPYLGELATGVDIAMAAADVAAGRRPETTPTRRRAAAITFLYPERDT
                     EIESVTVHEDRLTPEIHSAEPMADPGAVLRLPPRGYISRYARVIALADSMERARAALLG
                     APEIVEIAGRPAQEPPR"
     gene            18735..20030
                     /gene="stzI"
     CDS             18735..20030
                     /codon_start=1
                     /gene="stzI"
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 260.3; E-value: 3.5e-79)"
                     /gene_kind="transport"
                     /product="MFS-type transporter"
                     /protein_id="QBF29333.1"
                     /transl_table=11
                     /translation="MTTGQTSAGPGKAGRPSVLETLRGIPGPIWLVLVGMLVNRLGNFL
                     QIYLVLYLTAKGFSATEAGFALGAYGVGSVVGVLVGGSASDRIGYAWTIVGSMALAGLG
                     TLSLPHLGSLPLVIVVAAVIGLLAQMYRPASSALLVERTPEHHHVMVFAVYRMAFNLGT
                     TVGPLLGALLISHSYNLIFYLEAGAQLSFAVFALVLARSGGMAEQAERHADAPRRSYAA
                     VLRDTRYVLFLLALFLNAVVYIQHTSALPLQIKADGHGVAFYSSLLSLNAVMVICLELL
                     FTKYVQHLPGKVAVALGIGLVGVGMNLYVAGPGMAMYVVATVVWTAGEMIGTPTASAWP
                     GKVAPEHLRGRYIAAAAFPMQIGYAVGPVLGVAAWQLSHASVWWLSGLLTVGAVAATLA
                     GMSERRTDHGTGTAEAGEQPAGHGGPVAADTP"
     gene            20074..21030
                     /gene="stzJ"
     CDS             20074..21030
                     /codon_start=1
                     /gene="stzJ"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1066:alpha/beta hydrolase domain-containing protein
                     (Score: 205.6; E-value: 1.7e-62)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative alpha/beta hydrolase"
                     /protein_id="QBF29334.1"
                     /transl_table=11
                     /translation="MAYAEGIEKFVETVNGALPPDFYTYPVERQRVLYDSLTEVLPIPV
                     PEGVRHRDATVTHEGRTARVRVYEPAGRTGDAVLFYIRGGGFVIGSLHSHHSLVAELAD
                     RTGLVAVALDFGMAPENPFPGPLEDCYAGLCGTLADLPALGLGDLDPDGAVICGESSGA
                     NMAVVLSMMARDRGGPRPRGQAVISPVLDFTRWRHGGEDAPLLSGGEMEFYTACYCPKP
                     EQAADPYVSPLLGGDFRSLPPAYVVGCAMDSLCVDAEKYTALLREHGTPVTYVREEGMV
                     HAPVRARRVSEPAADFFARYCAAVSALARKEAADGGR"
     gene            21017..22291
                     /gene="stzK"
     CDS             21017..22291
                     /codon_start=1
                     /gene="stzK"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1063:argininosuccinate lyase/adenylosuccinate lyase
                     (Score: 68.2; E-value: 1.2e-20)"
                     /gene_kind="biosynthetic-additional"
                     /product="ATP-dependent N-fumaramoyl-DAP-amino acid ligase"
                     /protein_id="QBF29335.1"
                     /transl_table=11
                     /translation="MAGADPGTGPGRGPCVIVDPYSSGALFADALRERGVPVAAVVSSP
                     RPPEAYASSYRPQDFPDVIVHDGDLDEVVERVRALDPRCVLAGCESGVELAERLSPRVL
                     PGLSNVPALAEARRDKSRMADAVRAAGLPVIPQLCTADAEEAAGWLEREGLTGADLVIK
                     PPKSASTDGVIKVPGGAGWRAVFERQIGRVNQFGEVDDRLIVQKFVTGTEYVVDTFSHD
                     GKHSLVDVCAYGKVDNGPHMAVYDTMRWLPPDDPAVPALADYVFGVLDAVGIRFGSAHV
                     EVMGTADGPLLIELGARPHGGGQPRFNRNATGDSQIDRTVRWLTGGELPQSYELLTQQM
                     CVFHMARRSGTVSGTAVLDEIRTLPSHHFSVQNLSDGDRVPVTKDLVDSLDFGFVILAH
                     PDPEQIERDYRAVRALERRLVITGP"
     gene            22288..22920
                     /gene="stzL"
     CDS             22288..22920
                     /codon_start=1
                     /gene="stzL"
                     /gene_functions="transport (smcogs)
                     SMCOG1116:Homoserine/threonine efflux protein (Score:
                     146.3; E-value: 1.5e-44)"
                     /gene_kind="transport"
                     /product="putative membrane protein"
                     /protein_id="QBF29336.1"
                     /transl_table=11
                     /translation="MIHALAFLTSSLVVIMAPGPDLALITRLVLTGSPRTAVPAAFGMI
                     TAGALQAALGALGLSALLAARPDLFAAFRWAGAAVLLVWGCRALRAALRAPDTTESGAR
                     AEPDDTPRGRRRAFALGLLCTGSNPKVGIFLMAFLPQFVPAGLHPATGVAVLACCYLAL
                     VLAWLLAWTKLVHRLSRHLHSARAQRLTNGLTAVVFGVFALRLALGG"
     gene            complement(22958..24994)
                     /gene="stzM"
     CDS             complement(22958..24994)
                     /codon_start=1
                     /gene="stzM"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1041:transcriptional regulator, SARP family (Score:
                     446.7; E-value: 3.3e-135)"
                     /gene_kind="regulatory"
                     /product="regulatory protein AfsR"
                     /protein_id="QBF29337.1"
                     /transl_table=11
                     /translation="MRALRDIESGRVEQPQTRTLRRLADVLGLDVGDIRTSVSRSRRPA
                     NPGEPGLRIGILGALSIDRGGTVTEVRACKLRRLLSLLALCHPESASLDEIGRTLWPKE
                     PPRSYQNLIHTYVSQARGLLRVPGAGQADPSPLIRTPIGYALSVGRDQIDLTRFQDLAD
                     RARRAHAGGDPAAAYEFAALAHRCWRGPILTEEPQLALHPAATAATRQRTENLLLYAEL
                     AVRFHQPELVVPALYTAAEDEPLNERLQARLMLALACCGEQSEALRVFAEVSRRLDAEL
                     GLQPGQELRQAHVRILQQQLTAPGGAPAARQPAAAPRDPVVPAPAPAGPPEARPSQLPG
                     LNRHFVGRAAHLRELDRLLLAPGERDGQVPAALITGPPGVGKTALALRWAHRVLGRFPD
                     GQLYVDLHGHARQRPLDALEAMASFLRALGVPGDRIPGTLGEATSLYRTRLSGRRVLVL
                     VDNAWDEEQIRPLIPGDAGCAVLVTSRNALPDLAAREGVQRVALDGLDDDEALALLGRL
                     LGPERVGREPLAAMALGKYCGGLPLVLRTLATRLVQHPCLGIAQYYTGLQIGGLSPQPA
                     DAGDGLLCSVQAAFELSYRVLPEPARRVFRLLGRTRGTDITSYTLTELAGLPPGEARWA
                     LCRLADASMVREHVLGRFDVPAPLLRYARTLLGQEEAERFRTA"
     misc_feature    complement(24758..24760)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS             25489..26751
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1244:amidohydrolase (Score: 383.4; E-value: 1.6e-116)"
                     /gene_kind="biosynthetic-additional"
                     /note="orf+1"
                     /product="putative hydrolase"
                     /protein_id="QBF29338.1"
                     /transl_table=11
                     /translation="MTPTPRTAGGTPDGPAPAGPALLDEARRLAPGAVALRRALHRGPE
                     LGLGLPATQRLILDALDGLGLDIRTGRALSSVTATLTGAADGPTILLRADMDALPVTED
                     TGLPFASRGPGLMHACGHDVHMAMLVGAARLLAGRRETLPGRVVFMFQPGEEGHHGARL
                     MIEEGVLEASGSRADAAFALHVNPNMPAGAVLLRPGPQLAASDRFRVVVHGRGGHASAP
                     HTTCDPVPVACEIVLALQSAVTRGVAADDSAVLSVTRLAAGTATGVIPDTAELAGTLRT
                     LAGPTRQRLHEAIARVAHGVAAAHGATAEAAVVPGYPVSVNDAGMTALVRRAAAGALGA
                     GAVHDLPAPQMTAEDFSYVLRAVPGALAFLGACPPDRAPDEAPSLHSPRMTVDEDVIAT
                     GIACEAAVALAFLAGRGRLDG"
     CDS             26825..28252
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 114.9; E-value:
                     5e-35)"
                     /gene_kind="transport"
                     /note="orf+2"
                     /product="multidrug resistance protein"
                     /protein_id="QBF29339.1"
                     /transl_table=11
                     /translation="MREPVAPSSVHTPPATAAGSGGIFSPPHLAATLTFAVVMFLTGFA
                     ALAVVPTLPTAARDLDGVSLFPVVAGCFVAAGLFGGVLGGHWADRSGARRPLALGMVLS
                     VLTLLVSASSGSVWQLAAGRFVDGLAAGLVAVSVTTAVGQCYPEHLRPRMLALLSAGWV
                     LPSLLGPPLAGLVVQWWSWRAVFYGLAALTALPAVALVLVLRRAPGTAPGTAPGAASRV
                     AEVPAERPPLLVAALLSLGAALGQYGASAWDPRHLAAVAAGVILLVVLAPRLLPRGTWR
                     GARGLPVTVLLRGLTSGTYFAVEALVPLMLITERRVAAVVVGAAFTASAVLWAAASWVQ
                     GRVLPHIARHRLVTAGALVMAAAVALAAAGCSGGLPPVTAAAAMPLSAVGMGLLDPCVT
                     VLSLKHSPPHRQGHTTSALQTNMNLGQVVVLALASAVLNACLAAGAGPLPGYRAAFALL
                     LLPPLLVALLAVRARGD"
     CDS             28300..29607
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1030:serine/threonine protein kinase (Score: 196.5;
                     E-value: 9.8e-60)"
                     /gene_kind="regulatory"
                     /note="orf+3"
                     /product="serine/threonine-protein kinase"
                     /protein_id="QBF29340.1"
                     /sec_met_domain="Pkinase (E-value: 5.1e-38, bitscore:
                     121.6, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERIGGYLVERRLGEGGMGTVHLARTRGGRAVALKVAKAELAADP
                     VFRERFRSEVEAARAVGGFHTAPVVDADVDGDPLWLATAYIPGPTLAERLAAEGAMDEA
                     GLRALAAALAEALESIHSCGLVHRDLKPGNIIMAADGPRVLDFGIARAVESTRLTATGT
                     AFGTPGFLAPEQALGHEVTGAADVFALGAVLVAAAGGSAWGEGTPMGLMYRSVHEPPDL
                     STVPAGLRDVVAQCLAKEPSARPTPAALLDRLTGPAPRPAGWGPGPATPPYAPGTPAAP
                     PYPPAGDPRQPSGTPPQPFPVPPAPATPPQPYAAAPQARPAPPQAPLTPHQTPTAYGFG
                     PPVPYAGPEVALADGDSGAVVNATGVQLEVGGVAADFPWHEVARVDRGRRGHHLTLTVR
                     LWDGGVYSCELNARRRARLTEWVARLDPVLAHYLNR"
     CDS             complement(29757..30500)
                     /codon_start=1
                     /note="orf+4"
                     /product="nitrate regulatory protein"
                     /protein_id="QBF29341.1"
                     /transl_table=11
                     /translation="MTTAARGPHGGRSAPLAVGVRTEGGRALLGARGELVHGCADTLAG
                     TLAALPPGTARVDLDASEVVFLDTAGLTALVTLREYGRRRDVPVSATGWRGQPRRVLEL
                     MGLDPADPLSGTLPTALTDRAASAVAQERAEQLDTLRLEIAQLRHAIDSRPVIDQARGI
                     LMAAHTCTPDQAWEILREASQRTNTKLRQVASAVTASAAPDGTPPPEPLRSALAAAVRR
                     VSTAARAPRESCGRSPARAGRRAAG"
ORIGIN
        1 gagcgccgca tccgcgacat ccagtcccag atgacccgcc tcgccaccgg cggcgacccc
       61 gcccagctga ccgccgtcca gaacgaactc tgggtcctcc agcagtacga ccaggccctg
      121 cgggaacggg gcgcggaggc cctctgacgg gtcagccgtc ccccttgggg atgcccgggc
      181 ggcgcagggc gcggatcacc tgcatgtcca tccccctcgt tccgcggccc gcagttgccg
      241 gtcgcatagt ccgacgagtc gcataaccgc ccggtcaccg gacggatgca aaaagtcacc
      301 gcacgcccct cgtggcggtg ttgtgtcgta ccccacactg ggggcggtgc ccgagcctcg
      361 gagcgcacgc tgccgctcgg cttcgcagcg atcatcctgg aggtcgcccc ccgtgcagac
      421 ccggaccctc gcccagaccg acagcagtac gagcgccacc cgcaccgacc cggacgagcc
      481 cgacgcggag accggcgtcc tcgtggccgt acccccgcgg gaccgggccg gggacctgga
      541 cccggagccg gccgccgagg aggcggagga ggccgcggga gaggcggagg ggccggacga
      601 gtcggagccg gacgagcccg tggaggccga ggtcccggtc gtcgcgcggg cggagtccgg
      661 cgggccctcg gccgacctgt tccggcagta cctgcgcgag atcggccgca tcccgctgct
      721 caccgccgcc gaggaggtgg aactcgcccg ccgggtcgag gccggcctct tcgcggagga
      781 gaagctcggc accaccccgg acctggacag cgaactggcg ctcgacctgg accgcctcgt
      841 cgtcatgggc cggatggcca agcgcagact catcgaggcc aacctgcggc tggtcgtctc
      901 cgtcgccaag cggtacgtcg gccgcggcct gaccatgctc gacctcgtcc aggagggcaa
      961 cctcggtctc atccgggccg tggagaagtt cgactacgcc cgcggctaca agttctccac
     1021 ctacgccacc tggtggatcc gccaggcgat gtcccgggcg ctggccgacc aggcgcgcac
     1081 gatacgcgtc ccggtgcatg tggtggagct gatcaaccgg gtcgtccggg tgcagcggcg
     1141 gatgctccag gaacgcggcc acgaacccac cgccgaagag gtcggcgccc atctcgacct
     1201 gtcgcccgag cgggtccgcg aggtgctgcg cctcgcccag gagccggtct cgctgcacgc
     1261 accggtcggc gaggaggacg acgtcgccct cggcgacctc atcgaggacg gcgacgccgc
     1321 gagcccggtg gagtcggccg ccttcctgct gctgcgcgag cacctggacg cggtgctgtc
     1381 cacgctgggg gagcgcgagc ggaaggtcgt acagctgcgc tacggcctgg ccgacgggcg
     1441 cccgcgcacg ctggaggaga tcggccggct gttcggcgtg acccgggagc ggatccgcca
     1501 gatcgagtcg aagaccctca gcaagctccg cgaccacacc ttcgcggaac agctgagggg
     1561 ctacctggac tgaggggccg ccgccgggcg gcggcccccg cgcctagtcc acctcggcca
     1621 cggcctgtgc gaactgcgcc tggtacagcc gggcgtacgc cccgctggcc gccaacagct
     1681 cggcgtgcgc gccctgttcg acgatcgacc cgttctccat cacgaggatg gtgtccgcgt
     1741 cccggatcgt cgacagccgg tgcgcgatca cgaacgacgt acggcccgac gccagtttgg
     1801 ccatcgcctt ctggatcagc acctccgtgc gcgtgtccac ggaactcgtc gcctcgtcca
     1861 gcaccaggat caccgggtcg gacaggaacg cccgcgcgat ggtgatcagc tgcttctcac
     1921 cggcgctgac gcccgtgccc tcgtcgtcga tcacggtgtc gtagccgtcg ggcagcgtcc
     1981 ggatgaaccg gtcggcgtgc gcggcccgcg ccgcctcctc gatctcgccg cgggtgacct
     2041 cgcgcgcggc gccgtaggcg atgttctccg cgatggtgcc gccgaacagc caggtgtcct
     2101 ggagcaccat gccgatcccg gcacggagtt cgtcccgggt catcctccgg atgtccaccc
     2161 cgtccagggt gatccggccg gccgagacgt cgtagaaccg catcaggagg ttgaccagcg
     2221 tggtcttgcc cgcgccggtc gggccgacga tcgccaccgt gtgtcccggc tccaccgtca
     2281 gcgacaggtc ctcgatcagc ggcttctcgg ggtcgtaccg gaacgacacg tgctccaggc
     2341 acacccgtcc gcgcagctcg gccggccgct cgcccggcac cgggtccgcc tcctgctcct
     2401 ccgcgtccag gagctcgaag atccgctcgg cggaggccac cccggactgc accaggttcg
     2461 ccatcgacgc gacctgcgtc agcggcatcg agaactgccg cgaatactgt atgaacgcct
     2521 gtacgtcacc gatcgacagg gcaccggagg ccacccgcag cccgccgacg accgccacca
     2581 gcacatagtt caggttcgac acgaacatca tcagcggctg catgatgccg ctgttgaact
     2641 gcgccttgaa cccggcctgg tagagcgcct cgttctgctc ggcgaactgc tgtgccgact
     2701 catcctgccg cccgaacacc ttcaccaggg cgtgcccggt gtacatctcc tcgatgtggg
     2761 cgttgagcgt gccggtggag cgccactgct gcacgaagtg cggctgcgac cgcttgccga
     2821 cccgggtggc gaccacgaac gacagcggga cggtgacgag ggccaccagc gccaggatcc
     2881 aggacaccca gaacatcatg accagcacgc cgacgatggt cagcaccgag ttgatcagct
     2941 gtcccatcga ctgctggagg gtctgcccga tgttgtcgat gtcgttggtc gcccgggaca
     3001 gcacctcacc gcgctggcgc ttgtcgaagt acgacagcgg cagccgcgac aacttggcct
     3061 gcacgtcctc gcgcatccgg tacatcgtgc ggttcacggc acggttgacc agccgcgtcg
     3121 cgaccgccat cagcaggccg gcgaccagga aggtgccgag ggcgagcagc agaacctcgc
     3181 ccacggccgt gaagtcgatg cccttgccgg gggtgaagtc ggtgcccttg agcatgtccg
     3241 cgacccggcc ctggccgcgc tcgcgcaggg agtcgagcac ctgctccttg gtggcaccgt
     3301 gcggcatctg ccggccgacg atgccggaga agaccaggtc ggtggcgcgg ccgaggatct
     3361 tcgggccgac cacgctcagg gccacgctga cgaccacgca cagcagcagg gcgtagatcg
     3421 tcagccgctc cgggcggaac cgggcgacga gccgcttgcc cgaccccttg aagtccatcg
     3481 agcgctggtc ggggccgccc ccggccatca tgcgtcccat gggcccggcc atcaggcggc
     3541 ctccgcttcc gtcagctggg agagcacgat ctcccggtag gtctggttgg ctgccatcag
     3601 ctcggcgtgc cggccggagc cgaccacccg gccctcgtcc agcacgatga tccggtccgc
     3661 gtcccggatg gtcgacaccc gctgggcgac gatcaccacg gtggcctcgg cggtctcccg
     3721 ggccagcgcg gcgcgcaggg cggcgtcggt ggcgtagtcg agcgccgaga aggagtcgtc
     3781 gaagaggtag atctccgggc gctgcaccag cgtccgggcg atggcgagcc gctgccgctg
     3841 accgccggag acattggtgc cgccctgcgc gatcggcgcg tccaggccgc cctccagctt
     3901 cgtcacgaag tccttggcct gcgccacctc cagcgcgtgc cacaactcct cgtcggtggc
     3961 gtccggattg ccgtagcgaa ggttcgtggc gaccgtgccg gcgaacaggt acggcttctg
     4021 cgggaccagc ccgacggtct tcgcgagcag caccgggtcg gcctcgcgca cgtccacgcc
     4081 gcccaccagc acctcgccgt cggtggcgtc gaacagccgg gggaccagcc cgagcagcgt
     4141 cgacttcccg ctgccggtgg agccgatcac ggccgtcgtc tcgccgggcc gcgccgtcag
     4201 gtcgatggac ctcagcaccg gctcctcggc acccggatag cggaagcccg cgcctcggat
     4261 ctccaggtgc ccgtgggagc gcagccgggc gacgggggcc gccggcggca cgacgctgga
     4321 ctcggtgtcc agcacctcct ggatgcgctc ggcgcagacc tcggcgcgcg gcaccatcat
     4381 gaacatgaag gtcgccatca tcacggacat gacgatctgc atcagatagg cgaggaacgc
     4441 ggtcaggtcg ccgatggcca tcccgccgct gtcgatgcgg tgcgcgccga accacaccac
     4501 cgcgatggac gacaggttca ccaccgtcat caccatcggg aacatcaggg ccagcagccg
     4561 gccggtggcc agctgcatgt cggtcagctc cgcgttggcc cggccgaacc gctcctgctc
     4621 gtaggagtcc cggacgaagg cgcggatcac ccggttgccg gtgatctgct cgcgcagcac
     4681 ccggttgacc gtgtccagcc ggacctgcat cgaccggaac agcgggcgca gccggcgcac
     4741 gatcagggtc acgcagacgc cgagcaccgg cacgacggcg accagcacgg cggacagcgg
     4801 cacgtccagg ccgagcgcga gcacgatgcc gcccacgcac atgatgggcg ccgacaccat
     4861 cagggtgaac gtcatcaggg ccagcgtctg gacctgctgg acgtcgttgg tggtacgggt
     4921 gatgagggag ggcgccccga agtgacccac ctcacgcgcg gagaaggact gcacccggtc
     4981 gaagacggca ccgcgcacgt cccggccgag cgccgaggcg gtccgggcgc cgtagtacac
     5041 ggctccgatg ttgcagacga cctggaccag cgagatgccg atcatcagga cgccgaagga
     5101 caggatgtag cccgtgtcgc ccttcacgac accgttgtcg atgatgtcgg cgttcagggt
     5161 gggcaggtag agggtcgcgc aggtctggag gagctggaac accaccagga gggcgatggg
     5221 tttcttgtag ggcctgaggt aggtccgtag aagtcgtatg agcacgctac gtctctcggg
     5281 gtcggcgaca ggggctggtc ggttgccctt ggcccccatc gtcggacact ccacccgcgt
     5341 tacctcaacc gattaacccg aaggtttctc ctctactggc cgatggtttc ggcaagttaa
     5401 cgcccgttaa gtcccgatag gtcctgataa gacctggcaa gtcccttagg gacggaatgc
     5461 ccccgggtgg gtctgctccc gcaccgccgt gaactgctgc cgcaccgcct gtccgagggc
     5521 cagttcctcg cccggctcca gcacctgcgc cgccgcgccc tgccaggccg gcggggtgcg
     5581 cggatcgagg gtgccctgcg acaccccgag cgcccaggcc gcctgccggg ccgcgccgat
     5641 cgccgcgtag tccgccggct gcggcacgac gacctgcgcg ccgaacagcg acggcgccga
     5701 ggcctggacg gcgggcagct ccgcggcggc gcccagcagg aagatccggc gcacctccac
     5761 gccccgcccg cgcagcacgt ccagcgcgtc cgccagcccg cagagcatgc cctcgaaggc
     5821 ggcccgcgcc aggtgctcgg gcttcatcga ctcgcgccgc agcccggcga gggtgcccgc
     5881 ggtgtgcggc aggttcggcg tccgctcgcc ctccaggtac ggcagcagca ccagcccgtg
     5941 cgcccccggc gtggacttca ccgccagctc ggacaggctc tccaggtccg gcaggccgag
     6001 cagttcggcg gtgccgcgca gggcgcgtac ggcgttcagg gtggtgacca ccggcaggtg
     6061 catgccggtg gcgtcggcga gcgaggtgat catcccggac tggtcggcga gcgcctccgg
     6121 gtgcacggcc gtcacggaac cggaggcgcc gagcgacacc accacgtccc cggggcccag
     6181 gcccagcccg aacgcggcgg ccatggtctc cccggtgccg gccgagatca gcagcccctc
     6241 cggggtggtg ccggccgcgt ccgagggacc gatcacctcc ggcagcaccg cctggtggcc
     6301 gagcgccagc tcgaccaggt cggggcgcca ggcgccggtg gccgccgacc agtacccggt
     6361 gccggaggcc ccgccgcggt cggtggtgcg ccgcaggggc cgtccgagca gctgccacac
     6421 cagccagtcg tgggcctgga gcaggacggc ggtgcgctgc gcgtgctccg gttcgttctt
     6481 cgccagccag cgcagcttgg tgaccggctg ggcggcgccc ggcacacagc cgacggcctg
     6541 cgcccaggcc tcccggccgc cgagcgcgtc caccagatcg gcggcggcga cctgcgcgcg
     6601 cttgtcgccg ccgaccaggg ccgggcggac ggtgttgccc tgggcgtcca gcgggaccac
     6661 ggcgttctgc tgggccgaga ccccgatggc ctgcaccccc tccagcagcc cgccgccggc
     6721 cgcctcaccg agggagagca gccagatctg cgggtcgacg tcgctgggcc ggccctccac
     6781 cggatgcggg gcgtacccct gtcgtagtac ggcaccggtg tccgtgtcgc agaccacgat
     6841 gcgtgtgaac tccggtgagc tgtccaagcc ggcgactatc cccatgcgga ggattttgcc
     6901 gtaccgccgc gcccggcctc ggcccagggc gccccagggg gaggaggtgc ctgtcgcggg
     6961 gcgggcgcgg gcccgtcgtg acctgccgcg ccgccggtca ggtggtgccg gtcccccagt
     7021 cgtcctcgcg ggtgccgtgg ccgttgcgct cccgcagcga gcggacccgg tgggccaccg
     7081 actccgggat gcggtcgccg accgtgtgga acgccttgcc ggcgtagacg cggccctgct
     7141 gggcggcggt ctcggcggtg ttgcggaccg cggggttctg cgcgatctgc tgggccgact
     7201 tcttcagctg ttcgtagcgc tcgcgtccgg ccttggtgcc gagtacgtaa ccgagggcca
     7261 gaccggcgag gaacgtgagc cggtagcgca tggctgccac ccttcccgtg cgttggtatc
     7321 tggtgcggcg ctggcgccga gggtaccgat tggcggagca cccccctgct tgcgctaatg
     7381 tatgtgtcgc agcgagcggc cgccccctgg cgaataccca ggtaggtacg ttcgatgcaa
     7441 cgaggcgatc ctccgtagct caattggcag agcagccggc tgttaaccgg caggttactg
     7501 gttcgagtcc agtcggggga gcttcggtcc tccgtagctc aattggcaga gcagccggct
     7561 gttaaccggc aggttactgg ttcgagtcca gtcgggggag cgctgaacga ggacccctca
     7621 ggggtccttt ttcatgtccc cgggaaccgc cgcgcccacg gcgctgtcct caaggtcatg
     7681 agcagcagcg cggaagccga ccatccgagg caggagatcg tatgagcggc tatgctgcgg
     7741 cagacggcgc gcacacttgt acgcgacacg ccgctatggg gcggtagctc agccggttag
     7801 agcagcggac tcataatccg tcggccgtgg gttcgagtcc cacccgcccc accaagcgca
     7861 ggtcagagaa acgttctgac ctgcggaaac gtattttcgg gctgccgaat tcggaatcct
     7921 gggccagcgg agtggagtgg gaccgtggcc aggggacgcg gggtttcaga acggctgtgc
     7981 gcgggcctgc gcgtcagggg cgacacgacc ggcgttgatg cgctcgctgt ggcggcgggc
     8041 gacggccacc aggcccggct gcggccgccg gcgcccaccc gggaacggtg tgagacgcgc
     8101 tgaagcaggg gccggggttc gtgggtcggc ctcctccggc cggtcagacc gctgcggctg
     8161 cacacgagac cttgatcggg gccggtgcgc accgttcggg aggcgggtgc cggctggtcc
     8221 gtcggacgac gccagcgact gttggctgag tgcaccgtcg gggggaccgc ggacccggcc
     8281 gggtggccgc ccctttcaca cgccctgaac cgccgcccgg acgtccgacg cgcatcgccc
     8341 gtggagccga gacggtgtca ggccccgctg gccgtcgcac gggaggcacc ggcgatacag
     8401 gtccggcggt gccgactcca ggccgctgac ggtgcggaac gtacggctgc ccgtggtggc
     8461 gagatcggca gtgcgccgcg ggtctcattc cggggtgggg ccttcggggg ccagtcgtcg
     8521 catgcggcct ctcatatgcg gacggccgag atcgtcggtc tcccgggcct gccgctccac
     8581 ggttgaatac cggtgtggca cggaagacgg tgggattcga cgaggacggt ctgcgggcgc
     8641 tggccgggac gcggtccttc gagcgggggc tggggtacct ggaagcggtg agcggtctgg
     8701 aggtggggga cggctcggtc accgccgtgg tgcacggtac ggatgtctac gaggtggagc
     8761 tcacccacgg cggggacgag gggatctcgg ggcggtgcga ctgcccgtac gggcaggagg
     8821 gaaacttctg caagcactgt gtggcggtgg ggctgaccgt gctgcggcgg gcgaagacga
     8881 ttccacacca gcgagccgcg gcgcgggcac gagcttccac cttggaaggg tggctttcgg
     8941 cgctgtcgcg tgacgaactc ctggcgctgg tgcgggaaca cgtcgccgag gaccgagaac
     9001 tgcgccggcg cctggagttg cgggccgccg ctgctcgttc cgacctccgc acggtccggg
     9061 atcgggtcgt cgccctgatc gatccccggc cgttcgcccg gtacgggtac atcgagtacg
     9121 tggatgccgc tgggtatgcc cggcaggtgg ccgaggcggc ggacgcgctg cgcgccctga
     9181 tcgccggcag gcaggcggcg caggcggtcg gcctggccga ggaggcgctc cgggcgctgg
     9241 gggaggcgta cggggagatc gacgaccccg acggtgtgat cggggaggcc gccgccgcga
     9301 tggcgaaggc ccatctggag gcctgcgggg ccgcccgccc cgatccggac cggctggccg
     9361 agtcgctggt cggccacctg ctcggcgacg gcagtgaggt gacggacctg gatccgctcg
     9421 actacgccga ggtgctggga ccgagcggcc tggcccgaat gcggcagctg gcgaccgagg
     9481 cgctcaggcg caggccgtcc ggccgggcgg agcggtacct gatggaacgc ctggtcaagg
     9541 cgggcggtga cgtcgacgcg ctggtcgccc tgcacgccca ggaccttgaa ccgtcgggtg
     9601 ccacacatct gcgcatcgcc gaggaactcg aagcggcggg ccgcgcggac gaggcgcttg
     9661 cctgggcggg gcggggactg cgggactgcg ccgccgagac gcacgtcgac ggccgtctgg
     9721 tcgagtacgt gtgcgtccgg tacgcgaaga cgggacgggc ggcggacgcg gtcgcggtgc
     9781 ggcgggaccg gttccgtgtc gagcggtccc tggccgccta ccggcagctg cgttccgccg
     9841 cccgggcggc ggactgctgg gaggccgaac gcgcggcggc gctggccacc ttgagggagg
     9901 acgcccgtcg tgagcagggc ggccggtacg gcgggcctgt tctgatcgac gcgttgatcg
     9961 acgacggtga cctggacgcc gcctggcgtg aggcggccgg gcgggccggc gaccgccagt
    10021 gggagcggct cgccgacctg tcgcgtgaga cgcgtccggg tgaggcgctc gacgtgtacc
    10081 tccggctggt cgagcggtcg acggagccga ccggggaccg cgcctacgag cacctggcac
    10141 ggctgctgca gggcgtccgt gactgccatc gtgcgctggg caccgaggag gtgttcggcg
    10201 cgtatctcgg aggcctgcgg acagaactga aacgcaggcg gaagctgatg agcatcctcg
    10261 agcggcacgg gctgtgacgg tgggcgggcc cggcgtccgc tcatctgtgt gctggacggc
    10321 gtctgacggc ccgaggccgg tcagttcgtg agatcgatca tccgtaccgg ctgtccggtc
    10381 gtgcgggcga tcgtctcgac gtcgcggtcg tggtggagca gggtcagccc cgcctcttcc
    10441 gcggcggcgg cgaccagcag gtcgacgggg cccgcactgc ggtgctcgcc cttggcggtg
    10501 agcagttcct ggacgacgcg tgcgcgtcgg tagacgccgt cgggcatggg gcaccaggtg
    10561 tagtgggctt ccagcgcgcg ctttacacgt tcccggtctg ccgccgagcg ggatgagtag
    10621 aggacttcca gttcggtgat gtcacacagg gcgacgagtc ccgcgccgat cctgtcgtcc
    10681 cgctcggcgg tgctccggcc gagcaggacg cgggcgaggg cggaggtgtc gatcagatag
    10741 tcggcactgt ggagggggcg gcatcggcgg ggccggagcg gttctgttcg gcagggcgtg
    10801 acgtcatcgc ccaggcattc ctcccaaagg cccgcatcaa cgtcctcaac cggctcaccg
    10861 gcgctgacct ggaccgtctc gtcaccaatg ggctgggcga ggtcgccctc ggcatcgagt
    10921 cgggcagtga ccgcatcctg gccgccacgg acaagcggat cggcgccgag acgaccgagc
    10981 gcgtcgcccg ccgcctggtc gcccacggca tcggcgtgaa gggctgcttc atcctcggtt
    11041 tccccggtga aacccgatcg gacctggacg ccaccgttcg gcacatccgc aaccgccgga
    11101 atcgtgaccg gagatcccac tcgggcccac cggggccgaa gaaggggagt catcagtgcc
    11161 atcgcgcggc ggcagcgcac cgagccggtg ctgccccggc gccccgcacc ggatgccgga
    11221 cggtgtttcc cgaccgtccc tgcaaccctt tccccctccc cggtgttctg tctggtaatg
    11281 gatgagaagg ccgagcggca gctgaccgag cttctcgccg tggacctcga cggtggcttc
    11341 accgagctgg tcagggttca cggcagggcc gtgtacacgt tcctgctccg ggtctccggc
    11401 tcggccaccg aggcggacga cctggggcag gacgtcttcc tgcgcgccta caccgccttg
    11461 caggggtacg actccgagcg ccggcggcag ctcagtccgc gcccctggct gctcaccgtc
    11521 gccgccaacg tctggcgcaa ccacctgcgc acctgttcgc ggcggcccgc gctggcgggc
    11581 gtgcccgtgg aggacaccgc cgacacctgg accgaccgca gtccggggcc ggaggaactg
    11641 gccgcgctcg ccgaggaccg gcggcggctg gtcctggcgt tgctggagct gcccgagcac
    11701 caccgcgcgc ccgtggtgct ccggcacgtg ctgggactga gctacacgga agtggccgag
    11761 gtacagcggt gcgcggtcgg tacggccaag gcacaggtgt cccggggcct gaaggggctg
    11821 cgccggctgc tggagccgga gacggccctg ctggaggagg tgatgacatg aggagtgacc
    11881 gagaggtacc gcgcctcgac gcggcccggc ccggcctggc cgggctcgtc acggaaccac
    11941 cggcggactt cgccgcgcgc gtgctgcgcc gcgccggcgt cccgcgcgag cgctacgaca
    12001 cctatgtccg cctcggcacc gccgccggcg gtctctacgt ggcggcgagc ccggaggcgg
    12061 tgaccggggc cgcgctggac accggcgggc tgaccgcgcc gggcttcgag gaactgcacc
    12121 gctcccggac gaaccggtcg gccctgcggt cggccaagcc gttccccggg gtcaccaccg
    12181 cgctgcggac cggccgcgcc cggcgcctgc ccatcgacct gtccccgctc gccccggcgg
    12241 accgggcggt gctggaggcc gtacgcgcca tccccgccgg acagctgcgc ccggtcggct
    12301 ggatcgcccg ggaggccgcg gtggacccgg cggccgtgcc cggcgcgctg gccctcaacc
    12361 cggccgcggt gctgatcccc tgtcaccgtg tgacgtacga caacggcacc ccctgtgacg
    12421 ccgggtacct gcccggggcg ggggaggcgc tgcgcgccgc cgagggcatc gaaccggggc
    12481 gggtggcgga gctgcgccgg cgcggcgtgg tgttcctcgg cagcgacacc acccggatct
    12541 actgccaccc gacctgtgcc cacgcccgcc ggatcacccc gccccaccag gtgccgttcc
    12601 gtaccgcccg ggaagccgga cgggccgggt accgggcctg caagagctgc cggcctctca
    12661 ccgcatgacc ggacccgcga cggccaccac ccggcgtacg gtcccgaaga aaaccggagt
    12721 tgagccttgt caaccactca caccaccgcg gtggtcacca cgcaccccac cccgctgggc
    12781 ccgctggtgc tcggcgccac ggccgacgcg ctcgtgctgt gctgctacgg cgcggtggat
    12841 gacgcggtcg cccgcctcac ccggggcggg ctgcgcgccg tcgaggagga gcgcgcggac
    12901 ccggcgcagc tgaaggtcct ggccgagacc cgggaccagc tcgacgccta tctgaccggc
    12961 gcccggcggg acttcaccct gccggtggac ctgcggctcg ccaccccgtt cagccggcag
    13021 accgtcatgg cgctggacgc tttcgtgccg tacgggcgca ccgccaccta cgcggggctg
    13081 gccgaggcgc tcggcaggcc ccgggccgcc cgcgccgtcg gcacggccct cggcgccaac
    13141 ccggtctgcg tcgtgctgcc ctgccaccgg atcgtcggtt ccggcggcgg cctgaacggg
    13201 tacgcgggcg gcctggacgc caaacggttc ctgctcgccc tggaggcggg cgacggcccg
    13261 gcggccccct gaccggtggg cgccggccca tcccccgtcc ccggcgccca ccccttccct
    13321 tccgcatgtc catccgtcac ggagagccac ccgcgtgaac agctacgaca ccccgcccct
    13381 gcccggtctc gcggagccgg cgcccgccgg acgccccgcc cccgacggcg gcgtgctgcc
    13441 gcccctggac tggaccgccc tggcggccga gctggacgcg gagggcgtcg cgctcacccc
    13501 gccgctgctg gacgcggacc agtgcgcccg gctgcgggag atgtacgacg agccggcgct
    13561 cttccgcagc acggtgacga tggccaggca ccggttcggc gagggctcct accgctactt
    13621 cgcccacccg ctgccggagc cggtggcggc cctgcgccgg gagctgtacc cgccgctggc
    13681 ccgtatcgcc aacacctggg ccgcccggct cggcgaaccg gaattccccg accggcacga
    13741 ggacctcgtc gccgcctgcg ccgccgccgg gcagcaccgg ccgaccccgc tgctgctccg
    13801 ctacggaccg ggcggctaca actgcctgca ccaggacgtg tacggcgatc tcaccttccc
    13861 gctccaggtg gcggtgctgc tggaccggcc ggacgaggat ttcaccggcg gcgagagcgt
    13921 gttcgtggag cagcgcccgc gcgcccagtc ccggcccctg gtgcgccgcc cggtgcaggg
    13981 gcaggggctg atcttcaccg tccaccaccg tcccgtgcgc tccgcgcgcg gctggagccg
    14041 ggtgcagctg cggcacgggg tgagcgccgt gcacagcgga cggcgccatg tgctcggcgt
    14101 gatcttccac gacgcccgct gagcggggcg gcatccgggc gggccggccg cggcgcggcg
    14161 aaccgtgtac gaccgccgta ccggcccggt tctgccgcct cgctccagtg gcgccgcagc
    14221 ctcggcaacg gggctggtca gaggtgccct gccgcgttcc ggaaactgcc gctccggctg
    14281 gagagccgct ggagatcggc aacaaggtcg ttacatacgg tggctgtgcg acggcagggg
    14341 ggaaccgcgt cctgcctcgt accactgtca atccggcgac ccaccgttaa ggagcagtgg
    14401 cacacatgcg gcacgtacaa gaggcacggg cggtgcccgc cgagcacgag gcccgaccgg
    14461 ccccggtgac catgccggcg aacggctcgc cctaccgcct gggagcggcg ctgttgcagt
    14521 cgctcgcgca ggagatgaac gcgctggccg aacaggcgtc ggcgctgctg agcatgccac
    14581 cggagagcct gtccctggac gcggacgcct ttgcccagat cgcccgcaga aacgttccac
    14641 gctggcattt cgccatgctg aacgacaccg agcgcaacac cgcgctgatg accgccctgg
    14701 agcggggcat cccggcgggc gcgaccgtgc tggacatcgg ctccggcagc gggctgctgg
    14761 ccatggccgc cgcccgggcc ggcgccggcc gggtgttcac ctgcgagatg aacccgctgc
    14821 tggccgagat cgcccggaac gtcatcagcg cgcacggcat gtccgacgtc atcaccgtca
    14881 tcggcaagcc gtccaccgcg ctggacccgg tgcgtgacct cggcggaccg gtggacgtcc
    14941 tggtgtcgga gatcgtcgac tgcggactga tcggcgaggg tctgctgccc tccgtgcggc
    15001 acgcccgcga gcacctgctg aagccggacg ggatcatgct gccctcggcg gcccggctgc
    15061 acggccggct ggtcagcagc gatgaggtgc tgaagctgaa ccaggtcacc acggccggcg
    15121 gcttcgacgt ctcgctgatg aacacggtcg ctacccgcgg ccacttcccg gtccggctcg
    15181 acacctggcc gcaccggttc ctgtccgagg cggcgccgtt ggtcgagttc gacctggcgc
    15241 ggtccgcgct ggagcccggc gagcgccccc tcgccctgac cgccaccgcc gacggcgagg
    15301 tccaggccct cgcggtctgg ttcgagctgg acatgggcag cggcatcacc ctgtccaacc
    15361 cgccggacaa cccccgctcg cactggatgc agggctgggt gccgctggac aagccggtgc
    15421 cggtcaaggc gggggagacg ctcgccctgc ggctcggctg gagcgacttc accctccgcg
    15481 tgagcatctg acagcgcatc accccggcac cggtcacgag ccggcggccg tacctgtctg
    15541 caccaggacc tggagttagc gatgagtcac gtccccccgc acgtcccgtt cgagctcagc
    15601 ggcgcggaac tgcgcgacgc gatcgtgcag tacgccacca acccgatcta ccacgacaac
    15661 ctcgactggc tgaaccacga caacccctac cgccggcagc taaggccgca ggtgctgccc
    15721 cacctggact acgacaaggt cccgggccgg gagaacatcc tcaactacgc gagcctggcc
    15781 gtgcagcgcc tgctgacctc cgtctacgag gccgacctgg tgttcttccc caagtccggg
    15841 ctgaagggca aggaggagga cttccgggcg ttctacagcc ccgccaaccg ggcgctcggc
    15901 gagcggatcc ggccggcgct ggagcgctac gccttcggtt tcctcgacga cgaggtggag
    15961 acctccggca cctggaccgc gcagagcctg gacgcctacc tggactccct ggacaccgcg
    16021 ggcggcgcgg agcagtcccc ggtggagaag gccatcctcg gctcggccga ccgcgagcgc
    16081 gcggcccgga tgtggctggt gcagttcgcg ccggacttcc tctccgaggc ctcgccgatg
    16141 atgcgcaacg tgctcggcta ctacggcccg gcccagtccg agtggttcaa ggtcgtcatc
    16201 gacgagtacg gctacggcgt ccacgacacc aagcacagca ccctgttcga gcggaccctg
    16261 gagtcggtgg gcctggagtc cgacctgcac cggtactggc agtactacct gaacagcagc
    16321 ctgctgctga acaactactt ccactacctg ggcaagaacc acgagctgtt cttccgttac
    16381 gtcggcgcgc tgtactacac ggagagctcc ctggtcgact tctgccgccg cgcggaccac
    16441 ctgctgcgcg aggtgttcgg cgacacggtg gacaccacct acttcaccga gcacatccac
    16501 atcgaccagc accacggccg gatggcccgc gagaagatca tcaagccgct ggtggaggcg
    16561 cacggcgacg gcatcatccc ggagatcgtg cggggcatcg aggagtaccg ggtgctgctg
    16621 gagatcggcg acttcgactt ctccgagcag atcgcgtgga tggacgccca gcccgagctg
    16681 aagaagctgc acgacccggt cttcgagggt ctcaagcagg gcaaggtcga cgcccccgtg
    16741 gcgcacctgg tcgaaccgcg cggcgagctg tccaacaccc actgccacga cggtgacgag
    16801 ctgtgccaca tcgtctccgg caccatgcgc ttcgagagcg gcctgggctc ctcgctgacc
    16861 ctccaggccg gcgagggcgt cgtcatcaag cgcaaccggc tgcacggcgc gaacatcgag
    16921 tcggacgagt gcgtctacga gatccactcg gtgggggact accgaaagtg cctgtagtga
    16981 ccttctccgc cgaggggcgg gacaactgcg tggtcatcgc ggggacgccg tacgtctacg
    17041 cgacggtcgg cggccggggc ttcgtgatgc gggcccggtg cccgcaccgc ggcggccccc
    17101 tgcacctggc cggggtggcc gaggacgggg tacggctggt gtgcccctgg cacgagcgga
    17161 agacctccgt ggcccggatg cgggcggagg tccccgccgt gcgggtgggc ggccgggtca
    17221 ccgccgtctt cccggaacgg ccggcggccg gcggctggcc ggccccgccc caggactgcg
    17281 ccgtcgggct ggagcaccgg ccgctggcac ccgcgctgag ccgtccgtcc agggccggct
    17341 gagccgcccg ggccggccgg tccgccggcc cctgcaacgc cccggcgccg tccggtgttc
    17401 tacagaagcc cggtccgtgg ccgggggccg acgcggcccc cggccacgga ccgggccacg
    17461 aacgaccaca tgtgaggaga acggaacatg ggcagggacg gggacaagcc gctgctgctg
    17521 ctgatcggca gcagctcgcg gcgcagccgg gagttcatcc tgcggtcggt gagccggcgc
    17581 tacgcgctct ggctgctcca gccggcaccg gtgacctggg aggagccgta cgtcgtcggc
    17641 agtacccagg tcgacaacac ccgtcccgaa ctcctcgtcg aggccgcccg ccaggtggcc
    17701 gccgagcacg aggtgaccgg tgtgttctgt tacgacgagg gcctggtcac cccggccgcg
    17761 cacgtgtccg aggcgctggg gctgccgggc aactccccgg agaccgtgat cgcctgccgg
    17821 gacaagaacg ccacgcggac cgcgctggag cgggccgggg tcgcccagcc cgcctccatc
    17881 ggtgtgcggt ccctggccga ggcacaggcg gcggcggaca agatcggctt cccggtcgtg
    17941 ctcaagccgc gcggtctcgc cggcggcatg ggcgtgcgcc gggccgacgg acccgacgag
    18001 gtggacagcg cctaccgggc ggcgaccggc gtcacctacc cgggcgtgcc cgtcttcgag
    18061 gtgtccgtgc tggtcgagga gtacgtcgac gggcccgaga tcagcgtcga cgccgtcttc
    18121 ttcgagggcg agggcacccc gctggcggtg gcccgcaagc aggtcgggct cgcgccgttc
    18181 ttcgaggaga ccgggcacga ggtcgacgcg gccgacccgc tgctgtccga cccgcggctc
    18241 ctcgaggcgc tgcgggccag ccatgccgcg ctgggcttcc acaccggggt gagccacacc
    18301 gagttccggc tcaccgccga cggcccgcgc ctgatggagg tcaacgcccg cctcggcggt
    18361 gacatgatcc cctacctcgg cgagctggcc accggcgtcg acatcgccat ggcggcggcc
    18421 gacgtcgccg cgggccggcg tcccgagacc acgccgaccc ggcggcgggc cgcggcgatc
    18481 acgttcctgt accccgagcg ggacaccgag atcgagtcgg tcaccgtcca cgaggaccgg
    18541 ctcaccccgg agatccacag cgccgagccg atggccgacc ccggggccgt gctgcggctg
    18601 ccgccgcgcg gctacatctc ccggtacgcc cgggtcatcg ccctcgccga ctccatggag
    18661 cgggcgcggg cggccctgct cggggcgccg gagatcgtgg agatcgcggg ccggccggcg
    18721 caggagccgc cccgatgacg accggacaga cgtccgccgg gccggggaag gcgggccggc
    18781 cctcggtcct ggagaccctg cggggcattc cgggccccat ctggctcgtg ctcgtcggca
    18841 tgctggtcaa ccggctcggc aacttcctcc agatctacct ggtgctctac ctgaccgcca
    18901 aggggttctc cgcgaccgag gccgggttcg cgctcggcgc ctacggcgtg gggtcggtgg
    18961 tcggcgtcct ggtgggcggc tcggcctccg accgcatcgg ctacgcctgg acgatcgtcg
    19021 gctcgatggc gctcgccggg ctgggcacgc tgagcctgcc ccacctgggc agccttcccc
    19081 tggtgatcgt ggtggccgcg gtcatcggtc tgctggcgca gatgtaccgg ccggcctcct
    19141 cggccctgct ggtggagcgc accccggagc accaccacgt gatggtgttc gccgtctacc
    19201 ggatggcgtt caacctcggc accaccgtcg gcccgctgct cggcgcgctg ctgatcagcc
    19261 actcgtacaa cctgatcttc tatctggagg cgggggccca gctcagcttc gccgtgttcg
    19321 ccctggtcct ggcgcgctcc gggggcatgg cggaacaggc cgagcggcac gccgacgccc
    19381 cgcgccggtc gtacgccgcc gtgctgcggg acacccggta cgtgctgttc ctgctggcgc
    19441 tcttcctcaa cgccgtcgtc tacatccagc acacctccgc gctgccgctc cagatcaagg
    19501 ccgacgggca cggcgtggcc ttctactcca gcctgctgtc gctgaacgcc gtcatggtca
    19561 tctgcctgga gctgctgttc accaagtacg tgcagcacct gcccggcaag gtcgccgtgg
    19621 cgctcggcat cggcctggtc ggcgtcggga tgaacctgta cgtggccggg cccggcatgg
    19681 ccatgtacgt cgtggcgacc gtggtgtgga cggccggcga gatgatcggc accccgaccg
    19741 cctcggcctg gccgggcaag gtcgcccccg agcacctgcg gggccgctac atcgccgccg
    19801 ccgccttccc catgcagatc ggctacgcgg tcggccccgt cctcggtgtc gccgcctggc
    19861 agctgtcgca cgcgtccgtg tggtggctgt ccgggctgct gaccgtgggc gccgtggcgg
    19921 ccaccctggc cggcatgagc gagcgccgca cggaccacgg caccggcacc gccgaggccg
    19981 gcgagcagcc ggccgggcac ggcggaccgg tcgccgccga caccccctga cccgccccac
    20041 cgcaccccgg attcggaagc gagcgagccg cgcatggcct acgcagaagg catagagaag
    20101 ttcgtggaga ccgtcaacgg cgcgttgccg ccggacttct acacctaccc cgtcgaacgg
    20161 cagcgggtcc tgtacgactc gctcaccgag gtcctgccca tccccgtccc cgaaggcgtc
    20221 cggcaccggg acgccaccgt gacgcacgag ggccgcacgg cccgcgtccg cgtctacgaa
    20281 cccgccggac gcaccggcga cgccgtgctg ttctacatcc gcggcggcgg cttcgtcatc
    20341 ggctcgctgc acagccatca cagcctggtc gccgaactcg ccgaccgcac cggcctggtg
    20401 gccgtcgcgc tggacttcgg catggccccg gagaacccgt tccccggccc gctggaggac
    20461 tgctacgcgg gcctgtgcgg caccctcgcg gacctgcccg cgctgggcct cggcgacctc
    20521 gacccggacg gcgcggtgat ctgcggggag agttccggag ccaacatggc ggtcgtgctg
    20581 tcgatgatgg cccgcgaccg cggcggcccc cggccgcgcg gccaggcggt gatcagcccg
    20641 gtgctggact tcacccgctg gcgccacggc ggcgaggacg cccccctgct gtccggcggc
    20701 gagatggagt tctacaccgc ctgctactgc ccgaagcccg agcaggccgc cgacccgtac
    20761 gtgtcgccgc tgctcggcgg ggacttccgg agtctgccgc cggcctatgt cgtcggctgc
    20821 gcgatggact ccctgtgcgt ggacgcggag aagtacaccg ccctgctcag ggagcacggc
    20881 acgccggtca cctatgtgcg cgaggagggg atggtgcacg ccccggtgcg cgcccggcgg
    20941 gtcagcgaac ccgcggcgga cttcttcgcc cggtactgcg ccgccgtctc cgcactggcc
    21001 cggaaggagg ccgccgatgg cgggcgctga cccgggcacc gggccggggc ggggcccctg
    21061 tgtcatcgtc gacccctact cctccggagc cctcttcgcc gacgccctgc gcgagcgggg
    21121 cgtcccggtc gcggcggtgg tgagcagtcc gcgcccgccc gaggcctacg cctcctccta
    21181 ccggccgcag gacttccccg acgtcatcgt ccacgacggc gacctggacg aggtcgtgga
    21241 gcgggtacgg gcactggacc cgcggtgtgt cctggccggc tgcgagtccg gcgtggaact
    21301 ggcggaacgg ctctcccccc gggtgctgcc cgggctgagc aacgtgcccg ccctggccga
    21361 ggcccgccgg gacaagagcc ggatggccga cgccgtccgg gccgccgggc tgccggtcat
    21421 cccgcagctg tgcaccgccg acgccgagga agcggccggc tggctggagc gcgaggggct
    21481 gaccggggcc gacctcgtga tcaagccgcc caagagcgcc agcaccgacg gagtgatcaa
    21541 ggtgccgggc ggggccggct ggcgggccgt gttcgagcgg cagatcggcc gggtcaacca
    21601 gttcggcgag gtcgacgacc ggctcatcgt gcagaagttc gtcaccggca ccgaatacgt
    21661 ggtggacact ttcagccacg acggcaagca ctccctggtc gacgtgtgcg cctacggcaa
    21721 ggtcgacaac ggcccgcaca tggccgtcta cgacaccatg cgctggctgc cccccgacga
    21781 cccggccgtg cccgccctcg cggattacgt cttcggcgtc ctggacgcgg tgggcatccg
    21841 cttcggctcc gcccacgtcg aggtgatggg caccgccgac ggcccgctgc tcatcgagct
    21901 gggcgcccgc ccgcacggcg gcggccagcc ccggttcaac cgcaacgcca ccggcgacag
    21961 ccagatcgac cgtacggtgc gctggctgac cggcggcgaa ctgccgcaga gctacgagct
    22021 gctgacccag cagatgtgcg tcttccacat ggcccgccgc tcggggacgg tgagcggtac
    22081 cgccgtcctg gacgagatcc ggaccctgcc gagccaccac ttctcggtgc agaacctgtc
    22141 cgacggcgac cgggtccccg tcaccaagga cctcgtcgac agcctggact tcgggttcgt
    22201 gatcctcgcc cacccggacc cggagcagat cgagcgggac taccgggccg tgcgcgccct
    22261 ggaacggcgg ctggtcatca ccgggccatg atccacgcgc tcgccttcct gacgagctcg
    22321 ctggtggtga tcatggcacc gggtcccgac ctggccctga tcacccgcct ggtgctcacc
    22381 ggctccccgc gcaccgcggt gcccgccgcg ttcggcatga tcacggcggg cgccctccag
    22441 gcggccctgg gcgccctggg cctgagcgcg ctgctcgccg cccgcccgga cctgttcgcc
    22501 gcgttccgct gggcgggcgc cgccgtcctg ctggtctggg gctgccgcgc cctgcgcgcc
    22561 gccctgcgcg cgccggacac cacggagtcc ggcgcgcggg cggagccgga cgacaccccg
    22621 cgcggcagac ggcgggcctt cgcgctgggg ctgctgtgca ccggctccaa ccccaaggtc
    22681 ggcatcttcc tgatggcgtt cctgccgcag ttcgtgccgg ccggcctgca cccggccacc
    22741 ggggtggcgg tcctggcctg ctgttatctg gccctggtcc tggcctggct gctggcgtgg
    22801 acgaagctgg tgcaccggct gtcccggcac ctccactcgg cgcgggccca gcgcctgacc
    22861 aacgggctga ccgccgtcgt cttcggcgtc ttcgcgctgc gcctggccct cggcggatga
    22921 gcccggccgg ggcccggccg ggccccggcc ccggttctca ggccgtccgg aaccgttccg
    22981 cctcctcctg gccgagcagc gtcctggcgt accggagcag cggcgcgggc acgtcgaacc
    23041 ggcccagcac gtgctcgcgc accatgctgg cgtcggccag gcggcacagg gcccaccggg
    23101 cctcgcccgg cggcaggccg gccagctcgg tcagggtgta cgaggtgatg tcggtgcccc
    23161 tggtccggcc gagcagccgg aacacccggc gggccggctc cggcagcacc ctgtaggaca
    23221 gctcgaaggc cgcctggacc gagcacagca ggccgtcccc cgcgtcggcg ggctgcgggg
    23281 acagcccgcc gatctgcaac ccggtgtagt actgggcgat gccgagacag gggtgctgca
    23341 ccagccgcgt cgccagcgtc cgcagcacca ggggcagccc gccgcagtac ttgcccaggg
    23401 ccatggccgc caggggctcc cggccgacgc gttccggccc cagcagccgg ccgagcagcg
    23461 ccagcgcctc gtcgtcgtcc agcccgtcga gggcgacccg ctggacaccc tccctggccg
    23521 ccaggtcggg cagggcgttg cggctggtca cgagcacggc acagcccgcg tccccgggga
    23581 tcaggggccg gatctgctcc tcgtcccacg cgttgtcgac cagcaccagg acgcgccggc
    23641 cggacagccg ggtgcggtag aggctcgtcg cctcgcccag ggtgccgggg atgcggtccc
    23701 ccggaacccc gagggcgcgc aggaacgagg ccatcgcctc cagggcgtcg agcgggcgct
    23761 ggcgggcgtg gccgtgcagg tcgacgtaga gctgcccgtc cgggaagcgg ccgagcaccc
    23821 ggtgcgccca gcgcagcgcg agcgccgtct tgcccacgcc gggcggcccg gtgatcagcg
    23881 cggccgggac ctgcccgtcc cgctcgccgg gcgcgaggag cagccggtcc agttcccgca
    23941 ggtgggcggc gcggccgacg aagtgccggt tcaggcccgg gagctgggac ggccgggcct
    24001 cgggcggccc ggccggggcg ggcgcgggca cgacgggatc ccgcggggcc gccgccggct
    24061 gccgggccgc cggcgcgccg cccggtgcgg tcagctgctg ctgcaggatc cgcacatggg
    24121 cctggcgcag ctcctggccc ggctggagcc ccagttcggc gtcgaggcgc cggctgacct
    24181 cggcgaacac ccgcagcgcc tcggactgct cgccgcagca ggccagcgcc agcatcagcc
    24241 gggcctggag ccgctcgttc agcggctcgt cctcggcggc ggtgtacagc gccggcacca
    24301 ccagctccgg ctggtggaac cgcacggcca gctccgcgta cagcagcagg ttctcggtgc
    24361 gctgccgggt cgccgccgtg gccgccggat gcagggccag ctggggttcc tcggtcagga
    24421 tcgggccgcg ccagcagcgg tgggcgaggg ccgcgaactc gtaggccgcc gccgggtcgc
    24481 cgccggcgtg ggcccgccgc gcccggtcgg ccagatcctg gaagcgggtc aggtcgatct
    24541 ggtcgcgccc gacggacagg gcgtaaccga tgggggtgcg gatgaggggg gacgggtccg
    24601 cctggccggc gccggggacg cgcagcaggc cgcgcgcctg gctcacatag gtgtggatca
    24661 ggttctggta cgagcgcggc ggttccttcg gccagagcgt gcggcctatt tcgtccaggc
    24721 tggcggactc gggatggcac agcgccagca gggacaataa tctccgcagc ttgcaggcgc
    24781 gcacctcggt caccgtgccg ccgcggtcga tgctcagcgc gccgagaata ccgatgcgca
    24841 ggcccggttc acccgggttt gcgggtctgc ggctcctgga cacggaagtc cggatatcgc
    24901 ctacatcgag tccgaggacg tccgccaggc gtcgcagcgt acgcgtctgc ggctgttcca
    24961 cccggccgct ctcgatgtcc cgcagggccc gcacactgat ccccgacagc gcggcgaact
    25021 cccgctgggt caggccggtc tgttcccgga acgcgcggac ctgggccggg aagggaagtg
    25081 ccggcccggg gtggacagga cggtcggtga cagttccggt gatgcgaagg tccggcatgc
    25141 gccccccggt gccgagtgat gatcagcccc ctggcagtgc tcgattgctg gcgatcgtaa
    25201 gtcgaatggc ccggtggcgc aatttacgcc gcgtgaacat cgaatagcgg cggcgcatat
    25261 gcaccttggc ggaaatcgtt cggtgtgcgc tgttgtccgg aaaagcagat tgacaggagg
    25321 ggccgggggg aaagatgacg gggtttccgt catgctgtcg gcataccggc ctgtccggat
    25381 ccggggcgcc ggggccggcg gggaccgtcc ggccggcacc ccttccctgt ggcgggggag
    25441 cacccggcgc accgggtgcc gaccggtccc gggaaggaga gcggccgtat gacacccacc
    25501 cccaggaccg ccggcggcac gcccgacggt cccgcccccg ccgggccggc gctgctcgac
    25561 gaggcgcgcc ggctggcccc cggggcggtc gccctgcgcc gcgccctgca ccggggcccg
    25621 gaactcggcc tcggcctgcc ggccacccag cgcctgatcc tggacgcgct cgacggcctc
    25681 ggcctggaca tccgcaccgg gcgcgccctg tcctccgtga ccgcgaccct caccggggcg
    25741 gccgacggcc cgacgatcct gctgcgcgcc gacatggacg cgctgccggt caccgaggac
    25801 accgggctgc cgttcgcctc gcgcggcccc gggctgatgc acgcctgcgg gcacgacgtc
    25861 cacatggcga tgctggtggg cgcggcccgg ctgctcgccg ggcggcgcga gacgctcccc
    25921 gggcgcgtgg tgttcatgtt ccagcccggc gaggagggcc accacggggc ccgcctcatg
    25981 atcgaggaag gggtgctgga ggcctccggg agccgggccg acgccgcctt cgcgctgcac
    26041 gtgaacccca acatgccggc cggcgcggtg ctgctgcggc cgggaccgca gctcgcggcc
    26101 tccgaccggt tccgggtcgt ggtccacggc cgcggcgggc acgcctccgc gccgcacacc
    26161 acctgcgacc cggtgcccgt ggcctgcgag atcgtgctcg ccctgcagag cgcggtcacc
    26221 cggggcgtgg ccgccgacga cagcgccgtg ctcagcgtga cccggctggc cgcgggcacc
    26281 gcgaccggcg tcatccccga caccgccgaa ctcgccggca ccctgcgcac gctggccggg
    26341 ccgacccggc agcggctgca cgaggccatc gcccgggtcg cccacggggt ggccgccgcg
    26401 cacggggcca cggcggaggc ggccgtcgtc cccggctacc cggtctccgt caacgacgcc
    26461 ggcatgaccg ccctcgtccg gcgcgccgcc gccggcgcgc tcggtgccgg ggcggtgcac
    26521 gacctgcccg ccccgcagat gacggcggag gacttctcct acgtcctgcg ggccgtcccc
    26581 ggcgccctgg ccttcctcgg cgcctgcccg ccggaccggg cccccgacga ggccccgtcc
    26641 ctgcactcgc cccgcatgac cgtcgacgag gacgtgatcg ccaccggcat cgcctgcgag
    26701 gcggcggtgg ccctcgcctt cctggccggc cgcggacgcc tggacggttg accccggggc
    26761 ggacgggccg tagattcccg tgccgtccag ctcattggtc cagaccagag gtcgggggat
    26821 cggcgtgcgc gaacccgtgg cacccagctc ggtgcacacc ccgcccgcca cggccgccgg
    26881 ttccggcggg atcttctcgc cgccgcacct ggccgccacc ctgaccttcg ccgtggtgat
    26941 gttcctgacc gggttcgccg ccctcgccgt ggtgcccacc ctgccgacgg cggcccggga
    27001 cctggacggc gtgtccctgt tccccgtcgt ggccggctgc ttcgtcgccg ccggtctgtt
    27061 cggcggggtg ctgggcgggc actgggcgga ccggtcgggt gcccggcggc ccctcgcgct
    27121 cggcatggtc ctgtcggtgc tcaccctgct ggtgtccgcg tccagcgggt ccgtctggca
    27181 gctcgccgcc ggccggttcg tggacggcct ggccgcgggc ctggtcgcgg tgtccgtgac
    27241 caccgccgtc ggccagtgct accccgagca cctgcggccc cggatgctcg cgctgctgag
    27301 cgccggctgg gtcctgccgt ccctgctcgg accgccgctg gccggcctgg tcgtccagtg
    27361 gtggtcgtgg cgcgcggtct tctacggcct ggccgcgctg accgccctgc ccgccgtggc
    27421 cctggtcctc gtcctgcgcc gcgcccccgg cacggccccc ggaacggccc ccggcgcggc
    27481 ctccagggtg gccgaagtcc ccgccgagcg gcccccgttg ctggtggcgg ccctgctcag
    27541 cctgggggcg gcgctcgggc agtacggggc ctccgcgtgg gacccgcgcc acctggccgc
    27601 cgtcgccgcc ggtgtcatcc tgctcgtcgt cctcgcgccc cggctgctgc cgcgcggcac
    27661 ctggcgcggg gcccggggac tgccggtcac ggtgctgctg cgcgggctga cctccggcac
    27721 ctacttcgcc gtggaagcgc tggtgccact gatgctgatc accgaacggc gggtcgcggc
    27781 ggtggtggtc ggcgcggcct tcaccgcctc cgccgtgctg tgggccgccg cctcctgggt
    27841 gcagggccgg gtgctcccgc acatcgcccg gcaccgcctg gtcaccgcgg gcgccctggt
    27901 gatggccgcc gccgtcgccc tcgcggcggc cggctgctcc ggcggcctgc ccccggtcac
    27961 ggcggcggcg gccatgccgc tgtccgccgt cggcatgggg ctgctcgacc cctgcgtcac
    28021 cgtgctctcc ctgaagcaca gccccccgca ccggcagggc cacaccacca gcgccctgca
    28081 gaccaacatg aacctcggcc aggtcgtcgt gctcgccctg gcctccgccg tcctgaacgc
    28141 ctgcctcgcc gccggcgccg ggccgctccc cggctaccgc gcggccttcg ccctgctgct
    28201 cctgccgccc ctgctggtcg ccctgctcgc cgtccgcgcc cgcggcgact gagcccgggc
    28261 ggcggacgcg gcccgcccgg cggcggccat actgtccgca tggaacgcat cgggggttac
    28321 ctcgtcgaac ggcggctcgg cgagggcggc atgggaaccg tccacctcgc acgcacgcgc
    28381 ggcgggcggg ccgtcgcact caaggtcgcc aaggcggagc tggccgccga cccggtcttc
    28441 cgggagcggt tccgcagcga ggtggaggcg gcccgcgcgg tgggcggctt ccacacggcg
    28501 ccggtggtgg acgccgacgt ggacggcgac ccgctgtggc tggccaccgc ctacataccc
    28561 gggcccaccc tcgccgaacg gctcgccgcc gagggcgcga tggacgaggc gggactgcgg
    28621 gcgctggccg ccgcgctcgc cgaggcgctg gagtccatcc actcctgcgg cctggtgcac
    28681 cgcgacctca agcccggcaa catcatcatg gccgccgacg ggccgcgcgt cctggacttc
    28741 ggcatcgccc gcgccgtcga gtccacccgc ctcaccgcca ccggcaccgc cttcggcacc
    28801 cccgggttcc tcgcccccga acaggccctc ggccacgagg tgaccggtgc cgccgacgtc
    28861 ttcgccctcg gcgccgtgct ggtcgcggcg gcgggcggca gcgcctgggg ggaggggacg
    28921 ccgatggggc tgatgtaccg ctcggtgcac gagccgccgg acctgtccac cgtgcccgcg
    28981 gggctgcggg acgtcgtcgc ccagtgcctg gcgaaggagc cctcggcccg gccgacgccc
    29041 gccgcgctcc tggaccggct gacgggcccg gccccgcgac cggccggatg ggggcccggg
    29101 ccggccacgc cgccgtacgc gccggggaca ccggcggcac caccgtatcc gccggcgggc
    29161 gatccccggc agccgtccgg caccccgccg cagccgttcc ccgtgccccc ggcgcccgcc
    29221 acgcccccgc agccgtacgc cgccgccccg caggcccgac cggcgcctcc acaggcgcct
    29281 ctgacgcccc atcagacacc caccgcgtac ggcttcggac cgcccgtccc gtacgccggt
    29341 ccggaggtcg cgctcgccga cggggactcc ggtgccgtcg tgaacgcgac cggtgtgcag
    29401 ctcgaagtgg gcggtgtcgc cgccgacttc ccgtggcacg aggtcgcgcg cgtcgaccgc
    29461 ggccggcgtg gccaccactt gacgctgacc gtacgactgt gggacggcgg cgtgtactcc
    29521 tgtgagctga acgcccggcg cagggcccgg ctcaccgagt gggtggcccg gctcgacccg
    29581 gtcctcgcgc actatctgaa ccggtgacga agggcggccc tcggccgtaa cgatgccatg
    29641 aactgagctc gttcaggcgt gaaccggtcg cgtgctgggc acggacctcc taccggcgtg
    29701 ccgaaccggg tgccggcagg aggagggcgt catggaccgt cggatccggg tacgtgtcag
    29761 ccggcggccc gccgccccgc gcgggcagga gatcgaccgc aggactccct cggggcgcgt
    29821 gctgccgtac tgacccggcg gaccgcggcg gccagcgcgg accgcagcgg ctccgggggc
    29881 ggcgtgccgt ccggcgcggc gctcgccgtg accgccgacg cgacctgccg cagcttggtg
    29941 ttggtccgct gggacgcctc ccgcaggatc tcccacgcct ggtcgggggt gcaggtgtgg
    30001 gccgccatca ggatgccccg ggcctggtcg atgaccgggc gggagtcgat cgcgtggcgc
    30061 agctgcgcga tctcgaggcg cagcgtgtcc agttgctcgg cgcgctcctg ggccaccgcg
    30121 gaggccgcgc ggtcggtcag agcggtgggc agggtgccgc tgagcgggtc cgcggggtcc
    30181 aggcccatca gctccagcac ccggcgcggc tgcccgcgcc agccggtggc ggagaccggt
    30241 acgtcgcgcc ggcggccgta ctcgcgcagc gtgaccaggg ccgtcaggcc cgccgtgtcc
    30301 aggaagacca cctcggaggc gtccagatcg acccgggcgg tgcccggcgg cagcgcggcc
    30361 agggtcccgg cgagggtgtc ggcgcagccg tggaccagct cgccgcgggc gccgagcagg
    30421 gcccggccgc cttccgtacg gacgccgacg gccaggggcg ccgaccgccc gccgtgcggg
    30481 ccgcgtgccg ccgtggtcat gtctcccctc ccggtccgcc gatcctccgt agcccctcac
    30541 ctgcccccga ccccgcgccc tacacccgcc ggtctccccc cggcgcgagc cgcatcggcc
    30601 gggccgcgcc agacccgggg cgatcggggc cggccgggtg gtcacccgtg tgcgctcgga
    30661 cgggagccgt gcgcgccggg tgcgggccgt gcctgtgggt gtccgggttc gtgtccgtcg
    30721 gtccgggtgc gtgtccgccg ggcgcgggcg gtgtcggccg ggctccatcc ggtgttcgcc
    30781 gggggagcgc acgcgctggg ctctaccggt atgcgctggg cgcgagtcgt acgcgtcggg
    30841 tgtgggccgg gtctgtcggt gcgggttcgt gtctgtcggt ccgggtgcgt gtccgccggg
    30901 cgtgggcggt gccggccggg
//
