BGC0002295 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002295 (Streptomyces hygroscopicus)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS-like	1	9,315	minimycin/indigoidine	NRPS:Type I+saccharide	100%

BGC0002295 - Region 1 - NRPS-like

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Location: 1 - 9,315 nt. (total: 9,315 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 9,316
Label		BGC0002295

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002295	1.00	NRP, Saccharide	minimycin	Streptomyces hygroscopicus
BGC0000375	0.43	NRP	indigoidine	Streptomyces chromofuscus
BGC0001833	0.19	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001131	0.19	NRP	ambactin	Xenorhabdus miraniensis
BGC0002135	0.19	NRP	bovienimide A	Xenorhabdus bovienii SS-2004
BGC0001641	0.18	NRP	kolossin	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001758	0.18	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001135	0.18	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0001844	0.18	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0001873	0.18	NRP	pyrrolizixenamide A	Xenorhabdus szentirmaii DSM 16338

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002295	1.00	NRP, Saccharide	minimycin	Streptomyces hygroscopicus
BGC0000375	0.74	NRP	indigoidine	Streptomyces chromofuscus
BGC0001833	0.51	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001131	0.51	NRP	ambactin	Xenorhabdus miraniensis
BGC0002135	0.51	NRP	bovienimide A	Xenorhabdus bovienii SS-2004
BGC0001641	0.50	NRP	kolossin	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001758	0.50	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001135	0.50	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0001844	0.50	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0001873	0.50	NRP	pyrrolizixenamide A	Xenorhabdus szentirmaii DSM 16338

Similar known gene clusters from MIBiG 4.0

Module view

Legend

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 9315:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Gln)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

minA

Search NORINE for peptide: strict or relaxed

AMP-binding (20..431): Gln

nrpys: Gln

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAWQFGLINK
Nearest Stachelhaus code(s):: Gln DAWQFGLINK (100% 8Å match)
Stachelhaus code match:: 100% (strong)