BGC0002295: minimycin biosynthetic gene cluster from Streptomyces hygroscopicus
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Location: 5,879 - 15,193 nt. (total: 9,315 nt).
This entry is originally from NCBI GenBank MK122964.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002295
Short description minimycin biosynthetic gene cluster from Streptomyces hygroscopicus
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
  • saccharide (None)
Loci
MK122964.1
5879 - 15193
via Heterologous expression, Knock-out studies
Compounds
  • minimycin
  • indigoidine
Species Streptomyces hygroscopicus [taxonomy]
References
Chemical products information
minimycin Evidence: NMR [1], MS/MS [1]
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Chemical database entries
NPAtlas
indigoidine Evidence: Mass spectrometry [1]
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Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • QDX19368.1
  • minT
 5879 - 7138 (+) MFS transporter
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    • QDX19369.1
    • minA
    		 7443 - 11582 (+) NRPS(A-Ox-T-TE-Tau)
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      • QDX19370.1
      • minB
      		 11614 - 12567 (+) Pseudouridine-5'-phosphate glycosidase
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        • QDX19371.1
        • minC
        		 12603 - 14444 (+) HAD phosphatase and DUF4243 domain containing protein
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          • QDX19372.1
          • minD
          		 14471 - 15193 (+) Uracil phosphoribosyltransferase
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            Biosynthesis information

            Biosynthetic modules

            Name
            Unk01
            Type
            nrps-type1
            Genes
            minA
            Substrates
            glutamine (evidence: Structure-based inference, In-vitro experiments)
            Integrated Monomers
            Domains
            adenylation
            Annotation changelog

            Entry version: next

            Date
            Changes
            Submitters
            Reviewers
            2024-08-18
            MIBiG v4 annotathon
            • (ID: UIRGTKHZLIJCEPWJUIODIXHR)
            • (ID: 4CEPXXFDQQ46VQJXBT4B4AUO)
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

            Entry version: 2

            Date
            Changes
            Submitters
            Reviewers
            2022-10-07
            Changed chemical structures for compounds: minimycin.
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            2022-10-07
            Added NPAtlas links to compounds: minimycin.
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

            Entry version: 1

            Date
            Changes
            Submitters
            Reviewers
            2022-09-15
            Entry added
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            2022-09-15
            Added NRP substrate specificities
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            Detailed domain annotation
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