BGC0002300: albomycin delta2 biosynthetic gene cluster from Streptomyces sp. ATCC 700974
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Location: 6,184 - 34,320 nt. (total: 28,137 nt).
This entry is originally from NCBI GenBank JN252488.1.

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core biosynthetic genes
additional biosynthetic genes
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resistance
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General
Compounds
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Biosynthesis
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NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002300
Short description albomycin delta2 biosynthetic gene cluster from Streptomyces sp. ATCC 700974
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
JN252488.1
6184 - 34320
via Knock-out studies
Compounds
  • albomycin delta2
  • albomycin delta1
  • albomycin epsilon
Species Streptomyces sp. ATCC 700974 [taxonomy]
References
Chemical products information
albomycin delta2 Evidence:
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Chemical database entries
PubCHEM
albomycin delta1 Evidence:
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albomycin epsilon Evidence:
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List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AFJ20766.1
7955 - 8380 (+) hypothetical protein
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    • AFJ20767.1
    8423 - 9001 (-) N-acyltransferase
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      • AFJ20768.1
      8982 - 10331 (-) ornithine monooxygenase
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        • AFJ20769.1
        10402 - 12267 (-) hypothetical protein
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          • AFJ20770.1
          12315 - 13379 (-) D-cysteine desulfhydrase
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            • AFJ20771.1
            13376 - 15118 (-) carbamoyltransferase
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              • AFJ20772.1
              16496 - 17257 (-) deoxynucleoside kinase
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                • AFJ20773.1
                17254 - 18564 (-) serine hydroxymethyltransferase
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                  • AFJ20774.1
                  18603 - 19385 (-) sam-dependent methyltransferase
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                    • AFJ20775.1
                    19382 - 20359 (-) Fe-S radical SAM
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                      • AFJ20776.1
                      20548 - 21834 (+) seryl-tRNA synthetase
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                        • AFJ20777.1
                        21885 - 22403 (-) hypothetical protein
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                          • AFJ20778.1
                          22417 - 23247 (-) Fe-S radical SAM
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                            • AFJ20779.1
                            23724 - 24569 (+) putative ABC transporter
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                              • AFJ20780.1
                              24608 - 25336 (+) ABC-2 type transporter
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                                • AFJ20781.1
                                25341 - 26156 (+) ABC transporter
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                                  • AFJ20782.1
                                  26184 - 31163 (+) nonribosomal peptide synthetase
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                                    • AFJ20783.1
                                    31160 - 32101 (+) ABC transporter
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                                      • AFJ20784.1
                                      32148 - 32738 (-) nicotinamidase
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                                        • AFJ20785.1
                                        32992 - 34320 (-) nicotinate phosphoribosyltransferase
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                                          Biosynthesis information
                                          Annotation changelog

                                          Entry version: next

                                          Date
                                          Changes
                                          Submitters
                                          Reviewers
                                          MIBiG v4 annotathon
                                          • (ID: S5E5B42Z3YOMJFLKFTZJZTZN)
                                          • (ID: I3D2K5SU7JJDS2LEEQM3W3SO)
                                          • (ID: 4CEPXXFDQQ46VQJXBT4B4AUO)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                          Entry version: 1

                                          Date
                                          Changes
                                          Submitters
                                          Reviewers
                                          Entry added
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          Added NRP substrate specificities
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          Detailed domain annotation
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