LOCUS       BGC0002302             31758 bp    DNA     linear   BCT 03-AUG-2012
DEFINITION  [Ruminococcus] gnavus ATCC 29149 R_gnavus-1.0.1_Cont378, whole
            genome shotgun sequence.
ACCESSION   BGC0002302
VERSION     BGC0002302
KEYWORDS    .
SOURCE      [Ruminococcus] gnavus ATCC 29149
  ORGANISM  [Ruminococcus] gnavus ATCC 29149
            Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
            Mediterraneibacter.
COMMENT     Ruminococcus gnavus (16S GenBank Accession Number: L76597) is a
            member of the division Firmicutes. It represents 0.085% of the
            total number of microbial 16S rDNA sequences found in the gut
            (Eckburg et. al. (2005)) and 0.167% of the genomes sequenced within
            its division. The sequenced strain was obtained from ATCC (ATCC
            29149).
            We have collected 8.7X coverage in plasmid end reads and 454 reads.
            We will be performing one round of automated sequence improvement
            (pre-finishing).
            Sequencing/Assembly: The genomic DNA was purified from liquid
            culture derived from a single bacterial colony. A hybrid sequencing
            strategy that utilized reads from both 454 GS-20 and ABI 3730xl
            sequencers was devised and implemented to generate the draft genome
            sequences.  454 reads were assembled using Newbler (454 Life
            Sciences) into 454 de novo contigs. These de novo contigs were
            converted in silico to 800 base paired reads ('superreads') with
            400 base overlaps with neighboring superreads.  Finally, PCAP
            (Huang, et al, Genome Research, 13:2164, (2003)) was used to
            assemble the super-reads and the conventional 3730xl capillary
            reads.
            This sequenced strain is part of a comprehensive, sequence-based
            survey of members of the normal human gut microbiota.  A joint
            effort of the WU-GSC and the Center for Genome Sciences at
            Washington University School of Medicine, the purpose of this
            survey is to provide the general scientific community with a broad
            view of the gene content of 100 representatives of the major
            divisions represented in the intestine's microbial community. This
            information should provide a frame of reference for analyzing
            metagenomic studies of the human gut microbiome. Further details of
            this effort are described in a white paper entitled 'Extending Our
            View of Self: the Human Gut Microbiome Initiative (HGMI)'
            (http://www.genome.gov/Pages/Research/Sequencing/SeqProposals/HGMIS
            eq.pdf). These studies are supported by National Human Genome
            Research Institute.
            For answers to your questions regarding this assembly or project,
            or any other GSC genome project, please visit our Genome Groups web
            page (http://genome.wustl.edu/genome_group_index.cgi) and email the
            designated contact person.
            Annotation was added to the contigs in July 2007, and the CDS
            comments were updated in January 2008.
            This is a reference genome for the Human Microbiome Project. This
            project is co-owned with the Human Microbiome Project DACC.
            Product names were updated in August 2012.
            ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2024-10-17 17:17:19
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 7965
            Orig. end    :: 39723
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..1551)
                     /codon_start=1
                     /db_xref="InterPro:IPR008965"
                     /inference="protein motif:superfamily:IPR008965"
                     /inference="similar to AA sequence:INSD:EDK25040.1"
                     /locus_tag="RUMGNA_03512"
                     /note="KEGG: mpe:MYPE6470 1.4e-12 parC; DNA topoisomerase
                     IV subunit A K02621; COG: KOG1075 FOG: Reverse
                     transcriptase"
                     /product="hypothetical protein"
                     /protein_id="EDN75889.1"
                     /transl_table=11
                     /translation="MYMKSLKKIGILLFAVCFLMLYPSVSVHAAEGTFQFSDPTAKVGE
                     DVTVKAKISTGGEAIGDGFVTVTYDKAALEFVSGTNATGGDGTVKLEATGDGTVSELEY
                     TMVFKALKEGATKLEVSDYTSYLYSDETLNLTTGDSTVTVEAGDGTSSESSAGTTAVAT
                     GTGSVEIDGVTYTIYNDFSDALVPDGCSRTTMEYNGETVNAILQETSGKYFVYLVEGDK
                     DPVMALYNEKDNSFAITEMVSITDSSYIFLLGTNDGKGLPSQFKKTKLTVGTLTFPVWQ
                     NSESEDFYLMYAMNESGEESFYQYDTKDETYQRYPVTDVKEKSTSSSTTLIDKVKNFLQ
                     DQVLIVVAAAWAVILILIIIIIVVGVKLRRRNEELDEFYDEHESIGNSKGSRAVVEKKS
                     RKQFKGYQDEEDDFVDDFEDEEETDDEDPDEYEEYEDDDEYGEDDYDTYEDDSDEYEDD
                     FEEYDDDEYEDDDYDDEYDEYEDYDDDEEEDDVPEYQPKRRSSAREEKDSYDVDFIDL"
     subregion       1..31758
                     /aStool="mibig"
                     /contig_edge="False"
                     /label="saccharide"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..31758
                     /contig_edge="False"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(1..1551)
                     /locus_tag="RUMGNA_03512"
     gene            complement(1606..3195)
                     /locus_tag="RUMGNA_03513"
     CDS             complement(1606..3195)
                     /codon_start=1
                     /db_xref="InterPro:IPR004474"
                     /inference="protein motif:HMMPfam:IPR004474"
                     /inference="protein motif:HMMTigr:IPR004474"
                     /inference="similar to AA sequence:INSD:EDK25041.1"
                     /locus_tag="RUMGNA_03513"
                     /note="KEGG: bcl:ABC2055 0.0038 ponA; penicillin-binding
                     protein 1A/1B K05366; COG: COG1316 Transcriptional
                     regulator"
                     /product="cell envelope-like function transcriptional
                     attenuator common domain protein"
                     /protein_id="EDN75890.1"
                     /transl_table=11
                     /translation="MMYAMRKDRIMGDTRRRSRAVMSGADRRSSQRSGQPRRRPEQRNQ
                     MGDDRDKTQRQRSAQRKRPSGSTSANGRRSANGRPSQKGRSRKRAKRGFASWSTGKKAV
                     AILMGVLILLITATVAVVAAKWGKIGGVALNPDKLAISEEAEISGTGYLTVALFGLDTR
                     ETDEEMGSRSDTIMVASLNRETKEIKLVSVYRDTLLQLSDGTYNKANAAYAYGGEEEAV
                     AMLNKNLDLNIEHYVSVDFSVLVHVIDALGGIDINVEEAENGMDIIPYLNNYVVEVIKN
                     TGVDSAPFTQLGQQHLNGVQATAYARLRYGGGDDYKRTERQRQVLEQIAIKAQKAKLST
                     INKIIDKVFDNVKTNFTLTETIAYAKDVKSYIFGETQGFPYESTTADLDVGNSVVATDL
                     ASDVTKLHQFLFGENDYTPSSTVQSISEDISNSTYDTGESYDTEYDEYGYSQDYSGYDS
                     GYTDNSYGTGGYQDSGYGDGSSGNGYTEDTGGDYVPPSDGGGTDSGSSDSNSQIPDTGT
                     GDSGDTGGESLE"
     gene            complement(3268..4194)
                     /locus_tag="RUMGNA_03514"
     CDS             complement(3268..4194)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /db_xref="InterPro:IPR000358"
                     /db_xref="InterPro:IPR001173"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="protein motif:HMMPfam:IPR001173"
                     /inference="protein motif:ScanRegExp:IPR000358"
                     /inference="similar to AA sequence:REFSEQ:ZP_01355083.1"
                     /locus_tag="RUMGNA_03514"
                     /note="KEGG: stm:STM2085 2.3e-52 rfbN; LPS side chain
                     defect: rhamnosyl transferase K00754; COG: COG0463
                     Glycosyltransferases involved in cell wall biogenesis;
                     Psort location: Cytoplasmic, score:8.87"
                     /product="glycosyltransferase, group 2 family protein"
                     /protein_id="EDN75891.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 2.6e-13,
                     bitscore: 40.9, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEGNRTVDVLIPTYKPDQRCVQLVKRLLSQSVQVNRIYLIDTESG
                     IFPKELYTISDRVKIHRILPEEFDHGGTRNLGAEMSDAEILVYMTQDAMPADQFLIERL
                     LYGFSYENVAAVYARQLPAADCQFIERYTREFNYPKTSRLKSKEDLSKLGIKTYFCSNV
                     CAAYQKDVYERLGGFVRKTIFNEDMILAGRMIQAGWKIYYAADAKVIHSHNYNCRQQFH
                     RNFDLAVSQADHPEIFEGVPSEGEGIRLVKDTAKYLLKSGRPWLLVSLVCKSGWKYIGY
                     KLGKNYKKLPRWLILKCTMNPRYWRET"
     gene            complement(4181..5512)
                     /locus_tag="RUMGNA_03515"
     CDS             complement(4181..5512)
                     /codon_start=1
                     /locus_tag="RUMGNA_03515"
                     /note="COG: NOG19789 non supervised orthologous group;
                     Psort location: CytoplasmicMembrane, score:9.99"
                     /product="hypothetical protein"
                     /protein_id="EDN75892.1"
                     /transl_table=11
                     /translation="MLRKMIADRKIEYSSYTLVYAAAVLAAKAHLDYVTAVLLMAEAMF
                     LFIWNFRKTKNLVDMRGLFTLAWVGGEGIACLKLSRLQSDWSNVTWLTFFLIYVCFNLG
                     YDLWLGRFSKEQRQEVKRDEISAKRILICIFGLMAASIACFTLEAVVVGYIPLFNSAPH
                     AYSYFHISGVHYFTISCILIPALTVLYTKVTEKISVRTWILLIAGNLTAVAIPILCVSR
                     FQLLFAVGFAAVMYLMLYKKITWKMIVTGLLIMIPVYVLLTVARRHNVTYLNGIFEMKN
                     SKMPIFITQPYIYVANNFENFNCMVEQLTAHTWGLQMLFPFFALTGLKFVFPQLVTIPD
                     FVTKTELTTLTMFYDAYYDFGIIGTALFAFIIGLTAAAVSIPVRQKKNPMTYMFYGQIA
                     IYLGLAFFTTWFSNPTTWFWLALTLMMYWFVGYRRKGKGSHGRK"
     gene            complement(5528..6610)
                     /locus_tag="RUMGNA_03516"
     CDS             complement(5528..6610)
                     /codon_start=1
                     /db_xref="InterPro:IPR004474"
                     /inference="protein motif:HMMPfam:IPR004474"
                     /inference="protein motif:HMMTigr:IPR004474"
                     /inference="similar to AA sequence:INSD:EDK25041.1"
                     /locus_tag="RUMGNA_03516"
                     /note="COG: COG1316 Transcriptional regulator"
                     /product="cell envelope-like function transcriptional
                     attenuator common domain protein"
                     /protein_id="EDN75893.1"
                     /transl_table=11
                     /translation="MFRRRERISLQQRKRLNKKRQRRGILFLVLEFLILAVLVLAAFMM
                     YKLDHLNHNTLDESSLELHETPKGYTNVALFGLDSRDGELSGGVRSDSIMIVSINNKTG
                     DVKIISVYRDTLLKQQDGSYEKANAAYSFGGPQEAVAMLNRNLDLDITKYASVNFNSLA
                     DIIDILGGVEVELTSEEIFWLNGYTAETSQVVGRQTHTLDENSPGVHNLDGIQAVSYTR
                     IRYTAGDDFKRAERQRIILQKMIQKLKTAGPVKWNKILDQVLPEISTNMTTPDIMKLGL
                     NIFRYKIGETKGFPFDITTSENVIGLEGSYAVAIGHADNVRQLHEQLFGETGYQPSDEV
                     QQISQDVAYLTGVYPENYAQ"
     gene            complement(6626..8032)
                     /locus_tag="RUMGNA_03517"
     CDS             complement(6626..8032)
                     /EC_number="2.7.8.-"
                     /codon_start=1
                     /db_xref="InterPro:IPR003362"
                     /db_xref="InterPro:IPR012337"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Bac_transf"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1146:sugar transferase (Score: 357.7; E-value:
                     1.6e-108)"
                     /gene_kind="biosynthetic-additional"
                     /inference="protein motif:HMMPfam:IPR003362"
                     /inference="protein motif:superfamily:IPR012337"
                     /inference="similar to AA sequence:REFSEQ:ZP_01355012.1"
                     /locus_tag="RUMGNA_03517"
                     /note="KEGG: tcx:Tcr_1675 1.4e-72 undecaprenyl-phosphate
                     galactosephosphotransferase K03606; COG: COG2148 Sugar
                     transferases involved in lipopolysaccharide synthesis;
                     Psort location: CytoplasmicMembrane, score:9.99"
                     /product="undecaprenyl-phosphate glucose
                     phosphotransferase"
                     /protein_id="EDN75894.1"
                     /sec_met_domain="Bac_transf (E-value: 1.8e-77, bitscore:
                     249.5, seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKENQKLLNRIQVVLDAGVIIVAYVLSWYIRFRSGLFDLDPWYL
                     SLREYMKVLFFLVPSYLILYYAFQLYTPKRVQGRRLEAWHVVQANVIGLMGVTMVFFLA
                     KLSDRYSRWVVFIFCFVNITMEVFARNMVRMVLRKARKNGYNQKHMILVGYSRAAEQYI
                     DRILANPEWGYAVRGILDDHQPRGMEYKGIKVIGSIDNLLVILPQNQIDEIAITLGLDE
                     YHKLEYIVNMCEKSGVHTKFIPDYNNIIPTKPYTEDIQGLPVINIRHVPLNNALNKFVK
                     RAVDIFGAIVAIILFSPVMLVVSVLIKLTAPGPLIFKQERIGLQNKPFYMYKFRSMIVQ
                     KESEEKKGWTTKDDPRVTPVGKFIRKTSIDELPQLFNVLKGDMSLVGPRPERPLFVEKF
                     KEEIPRYMIKHQVRPGLTGWAQVNGYRGDTSIRKRIECDLYYIENWTLGLDFKIILLTF
                     LKGFINKNAY"
     gene            8259..9239
                     /locus_tag="RUMGNA_03518"
     CDS             8259..9239
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /db_xref="InterPro:IPR001173"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="protein motif:HMMPfam:IPR001173"
                     /inference="similar to AA sequence:REFSEQ:YP_001273902.1"
                     /locus_tag="RUMGNA_03518"
                     /note="KEGG: afu:AF0321 2.5e-41 glycosyl transferase
                     K00754; COG: COG1216 Predicted glycosyltransferases; Psort
                     location: Cytoplasmic, score:8.87"
                     /product="glycosyltransferase, group 2 family protein"
                     /protein_id="EDN75895.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 9.6e-34,
                     bitscore: 107.3, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVTIIIPNYNGKHFMEPCLASLNEQTCRDFKILIVDNASTDGSL
                     EYMEQTYPDIEVLALDSNYGFSRAVNEGIRHADTPYVILLNNDTTVDSRYVEEMIRAIE
                     VSDRIFSVSSKMIQMYHPDLIDSAGDLYTLMGWGVCRGAGRPVSNYTEDDTVFTACAGA
                     AIYRRSVFDKIGFFDESHFAYLEDIDVGYRAMIYGYKNRFCASALVYHVGSGTSGSKYN
                     TFKVKLSARNSVWLNYKNMPLLQLILNFIPLLLGYLVKYLFFCKIGFGTDYKNGIKEGI
                     HGLSKCRKVPFRMEHLGSYIRIEFALIRHTFGYAADWLKRKLLHK"
     gene            complement(9286..11991)
                     /locus_tag="RUMGNA_03519"
     CDS             complement(9286..11991)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /db_xref="InterPro:IPR001296"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045:glycosyl transferase group 1 (Score: 85.9;
                     E-value: 5.4e-26)"
                     /gene_kind="biosynthetic-additional"
                     /inference="protein motif:HMMPfam:IPR001296"
                     /inference="similar to AA sequence:INSD:AAT29366.1"
                     /locus_tag="RUMGNA_03519"
                     /note="KEGG: cno:NT01CX_0100 2.7e-08 glycosyl transferase,
                     group 1 family protein K00754; COG: COG0438
                     Glycosyltransferase; Psort location: Cytoplasmic,
                     score:8.87"
                     /product="glycosyltransferase, group 1 family protein"
                     /protein_id="EDN75896.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 3.2e-29,
                     bitscore: 92.4, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRDGISIENEACRSYVNMEQTGNMWELQEQDPQLHVYFTESVMG
                     VRLSFFLCIEGIEALNAVLYYKGKGEVFSEKQAYHFPLYLNRHIEKEIYFPYPAEAVRL
                     DLSDQNVVVKIEKLEIASASSENALNALKENMGQLGRKEKIAVLTHDMSNTGAPLLAYH
                     IAEKLKENGRDVVVLAANHGDGFLEEKYAEKEIPIFYLHDNARNQISVGWCGTKGESKN
                     WEAEEYLEHLMQLLREEGFCRVITNTVVSGKYVPLLKQYGFFIVSLIHEMKTTIELYGF
                     LSPGESIAYYSDYIVFPDYSVQKGFETLFPVIRGKCSIRPQGVYMQVDEEGDSRFSFEE
                     YGFSLDQKIVMCSGTCELRKGTDLFVSAAQILSRKEKTEEVHFVWTGKFSDPILEGWIY
                     NQIRQSNLEGKVHFIPFIKDKQKYHELLRHADVFWLTSREDPFPSVVLEAMKYEIPVVA
                     FKNSGGVNTMLDEGRGNLISEFDVEEMAKVTKQLLSERREEVLTGAKAWIEDKLKFDDY
                     IRYLEQLFQNKVQIVPEIDLYEIITPKLHEYFQGEVSSQIEKERIHQIQIMKDSKKFKF
                     SDDKIVFFDIADRTNYFEDKMVMKESGEICRDLFLDRPLICVPPYYCKKSAGELTGSRK
                     ILCGANVLSKQMEKSGQLLLLEQLMEYQGIYLMGAGVCDFTEGDQISDYTQNVLHFLLS
                     SKGVHAVRDEKTRYFLEQIGIHNVIRTGCPSLWSLTAQRCKKIPKEKGKEVLVVLEEKK
                     DCREEDSRMLNMLREEYETVYIWIKDRKNLDYLQKLGDLNKYKLLPGSISTLKKIFCET
                     AELDYIGTNIQIGIQSLTMLKRSLILSDTDYAQALREEMHLPVLGRSMQKEVEAWITAP
                     YETRVLLPEENIKYWKSQFVRKFARWYKKR"
     gene            complement(12091..12702)
                     /locus_tag="RUMGNA_03520"
     CDS             complement(12091..12702)
                     /codon_start=1
                     /db_xref="InterPro:IPR012338"
                     /inference="protein motif:superfamily:IPR012338"
                     /inference="similar to AA sequence:INSD:CAJ70578.1"
                     /locus_tag="RUMGNA_03520"
                     /product="hypothetical protein"
                     /protein_id="EDN75897.1"
                     /transl_table=11
                     /translation="MKKKYVLGILTVVVLMFGITACGKTTESTPEQNATQEEQKEDQDN
                     DTSDQDVNQDGQNEQDQTQQEQTENTQDANNLGAGTITVYAQNKDVSGFDKKEVSLEAI
                     TPETVLSQLAAAGVLPSDTTVLSFTKKEKDGEQVIDLDLSEKFGTYIKEMGSSAEYLVI
                     GSICNTYLDVYHCAKIHITVNGEMLATGHAEYPGYMTRFS"
     gene            complement(12718..13566)
                     /gene="rfbD"
                     /locus_tag="RUMGNA_03521"
     CDS             complement(12718..13566)
                     /EC_number="1.1.1.133"
                     /NRPS_PKS="Domain: NAD_binding_4 (49-162). E-value:
                     4.7e-15. Score: 47.2. Matches aSDomain:
                     nrpspksdomains_RUMGNA_03521_NAD_binding_4.1"
                     /codon_start=1
                     /db_xref="InterPro:IPR005913"
                     /gene="rfbD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score:
                     111.7; E-value: 7.7e-34)"
                     /gene_kind="biosynthetic-additional"
                     /inference="protein motif:HMMPanther:IPR005913"
                     /inference="protein motif:HMMPfam:IPR005913"
                     /inference="protein motif:HMMTigr:IPR005913"
                     /inference="similar to AA sequence:REFSEQ:YP_619620.1"
                     /locus_tag="RUMGNA_03521"
                     /note="KEGG: ljo:LJ1052 9.6e-95 dTDP-4-dehydrorhamnose
                     reductase K00067; COG: COG1091 dTDP-4-dehydrorhamnose
                     reductase; Psort location: Cytoplasmic, score:8.87"
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="EDN75898.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 1.9e-107,
                     bitscore: 349.2, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 5.8e-12,
                     bitscore: 35.9, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 2e-15, bitscore:
                     47.2, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRALVTGVKGQLGHDVMNELAKRGYEGVGVDVEEMDITDAAAVDS
                     VIREAKVDSVVHCAAWTAVDAAEDNEEMCRKVNAEGTENIAKVCKALDIPMIYISTDYV
                     FEGEGTRPWEPDDNVTQPLNIYGQTKYEGEQAVERLLDKYYIVRIAWVFGVNGKNFIKT
                     MLNLGETHDTLTVVDDQVGTPTYTYDLARLLVDMLEKDAYGKYHVTNEGGYITWYEFAK
                     EIFAQAGMDVNVVPVTSDKFPAKAKRPHNSRMDKSKLKKNGFTPLPTWQDALKRYLSEI
                     R"
     aSDomain        complement(13081..13419)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_RUMGNA_03521_NAD_binding_4.1"
                     /evalue="4.70E-15"
                     /label="RUMGNA_03521_NAD_binding_4.1"
                     /locus_tag="RUMGNA_03521"
                     /protein_end="162"
                     /protein_start="49"
                     /score="47.2"
                     /tool="antismash"
                     /translation="AKVDSVVHCAAWTAVDAAEDNEEMCRKVNAEGTENIAKVCKALDI
                     PMIYISTDYVFEGEGTRPWEPDDNVTQPLNIYGQTKYEGEQAVERLLDKYYIVRIAWVF
                     GVNGKNFIK"
     gene            complement(13646..15172)
                     /locus_tag="RUMGNA_03522"
     CDS             complement(13646..15172)
                     /codon_start=1
                     /inference="similar to AA sequence:REFSEQ:YP_001035696.1"
                     /locus_tag="RUMGNA_03522"
                     /note="COG: NOG07778 non supervised orthologous group;
                     Psort location: CytoplasmicMembrane, score:9.99"
                     /product="hypothetical protein"
                     /protein_id="EDN75899.1"
                     /transl_table=11
                     /translation="MRKIIDSVFRNIVVWFSLILVSFLAVVSFLFTSVFEWDESNQYLP
                     EVIHYKSDIFIITLAVCVFIIFLLYRTKYLERISLISMKIFLIISVLVLSLGWIFLTRP
                     VPVADDMMVSNAAVQFLNNDYSMLQKGGYVYQYVHQLGIIWLLEQIYRLFGAGNYLVYQ
                     MLNVLTLCVVYGCLLKLSKKIFKTETAERITVVILFMFCVPIFYTTFVYGNLIGLALSL
                     LGFVFLLEHFENRKLRYAVAFVVCAVLAVLVKSNYQVAMIAMAAVLFVDCMKSKKGWNL
                     LCIVLMFSLSFGAQAGLEKYYSARSGIELEKGASKLLWIAMGMQKGPLAEGWYDVSLID
                     MMNEASETGKTEGEVALNHIQESLKGFSENKKVAVEFYYHKIVSQWNEPSFEALWISNH
                     QPDQHPDGISKIAASFYYGRTGKILYKWFDVIHFLILSMAGIGIWKRRKQMELGELLLL
                     TTVLGGFFFHILWEAKSQYIWTYFILLIPTAAGGIREVGIWLDARGRKHS"
     gene            complement(15182..16636)
                     /locus_tag="RUMGNA_03523"
     CDS             complement(15182..16636)
                     /codon_start=1
                     /inference="similar to AA sequence:REFSEQ:YP_001273118.1"
                     /locus_tag="RUMGNA_03523"
                     /note="COG: NOG18565 non supervised orthologous group;
                     Psort location: CytoplasmicMembrane, score:9.99"
                     /product="hypothetical protein"
                     /protein_id="EDN75900.1"
                     /transl_table=11
                     /translation="MQCPIFSQKQEKSGILSKNSKCDIIHRRKTKRRKIMQKAWKKKSA
                     VYVPFVVLFLVELWIHKGIVPDFGDDLWFKEVACSEGFSFLTWLHQRYMEWSSRTAIEL
                     LLMITVRAPLYFWRIVDSALITCVAIFLSKMAIQKTEDSIYINTITSMLVVTITYTILN
                     SAGWIATTVNYMWPLSFGIMGLYPLRKFLEHEKINGFEMIFYSACLLIGANAEQMSVVI
                     LMAYVIFDLYCWFSTKKIYKYAAIQTGLSVLSLIYIILSPGNVIRKEKEIEAWFPVFAD
                     MSLFNKVDLGISAVIKEIFLQDNVFFFMMLFTLMVLIWQKYKKWQYRVLGAIPAFFLLS
                     LSKMHGYRGDERLPFSLVQEMGIFVGDRVYNYKTYIVVGSIIGVCCLILILFYLFGKNT
                     WTTWILIGTFVMGLATKAVMGFSPTVWASGYRTGWIMNFAFLFCTVFMLREWDFKNKNA
                     TCLLMGITAVCGVSGMIINYYSCMSI"
     gene            complement(16667..19111)
                     /locus_tag="RUMGNA_03524"
     CDS             complement(16667..19111)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /db_xref="InterPro:IPR001173"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="protein motif:HMMPfam:IPR001173"
                     /inference="similar to AA sequence:REFSEQ:NP_815842.1"
                     /locus_tag="RUMGNA_03524"
                     /note="KEGG: gbe:GbCGDNIH1_2152 6.8e-94 glycosyltransferase
                     K00754; COG: COG0463 Glycosyltransferases involved in cell
                     wall biogenesis; Psort location: Cytoplasmic, score:8.87"
                     /product="glycosyltransferase, group 2 family protein"
                     /protein_id="EDN75901.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1e-26, bitscore:
                     84.5, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNEFYVTAYRFHVKDRNTLLIQGWFAENEMGENQLVASIDDEKL
                     VYKTEQHTDVVDAHQCADGKAEIKNRMYLWVKLPKDWRNKKYLTLVNQCQNQMRESLRI
                     KISHLEKLENKIEHCIDGGTVGNQVFRVTGWFVSTEEVKITLYDSEDRKLDNVIKYKRR
                     NDVMRHYPECTEKEVHGFTAECSGSVPKKIKIVMKSGKQTARSELILKPSKIKKGIQKL
                     KKSGFKAYVYYQQFGIKRTIDRFYTKLTHKDEVSYKNWMKTHFPTEKMLAEQRKQHFTY
                     EPKISIVVPLYKTPEKYLDEMIDSIKKQTYGNWELCMSDGSGKDSPIKEKLCQYAAKDA
                     RIKVVHNENQLHISDNTNEALKICTGDYIAFGDHDDLLAPDAFYECVRLLNQDQTIEAI
                     YTDEDKISMDGKEHFQPHFKTDFNIDLLRSVNYICHLFVVKRSLFEKVGLLNHEYDGAQ
                     DYDFVLRCAEQAVNIRHIPKILYHWRAHKDSTAENPESKRYAFEAGIRAIQAHYDRCGI
                     DAEVSAEQLNGIYRSKYRLKEQPLVSVIIPNKDHTEDLDKCIRSIEEKGTYKNIEYIVI
                     ENNSEKKETFAYYEKLQAENPKVKVVFWEREFNYSAINNYGVGFAKGEYLLFLNNDTEI
                     INPDCIEELLGYCMRDDVGIVGARLYYEDDTIQHVGVIIGLGGVAGHTFVGEPKDSLGY
                     FGRIVTAQDYSAVTAACLMTKRKVFEKVNGFEEKLAVAFNDVDFCLKVREAGYLVVYNP
                     YAELHHYESKSRGLEDTEEKVLRFQGEIRTFQYRWKEILNEGDPYYSPNLTLDKTDFSL
                     RI"
     gene            complement(19121..19729)
                     /locus_tag="RUMGNA_03525"
     CDS             complement(19121..19729)
                     /codon_start=1
                     /locus_tag="RUMGNA_03525"
                     /product="hypothetical protein"
                     /protein_id="EDN75902.1"
                     /transl_table=11
                     /translation="MKKYIKTGIGILIIVVLAFLYAHIDKNSYLYDRNADTSAFISTGV
                     LLEGETISQEFVSEEDILDGLNIKCSVTGNVEDVEVQYILRDAKTNKKVASGSTKASEI
                     KNNKFNRFDIETVESAKGKEYLFEITETGADAANGVSFYVVPQKEEGAQVLSIKNNETQ
                     GALAARYISHRFDVETFVVLLGFVAFIVIFMKLLYKLFK"
     gene            complement(19745..20479)
                     /locus_tag="RUMGNA_03526"
     CDS             complement(19745..20479)
                     /codon_start=1
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 145.1; E-value:
                     4.5e-44)"
                     /gene_kind="transport"
                     /inference="protein motif:BlastProDom:IPR003439"
                     /inference="protein motif:HMMPfam:IPR003439"
                     /inference="protein motif:HMMSmart:IPR003593"
                     /inference="similar to AA sequence:REFSEQ:ZP_00134659.2"
                     /locus_tag="RUMGNA_03526"
                     /note="KEGG: cac:CAC2328 5.3e-55 polysaccharide ABC
                     transporter, ATPase component K01990; COG: COG1134 ABC-type
                     polysaccharide/polyol phosphate transport system, ATPase
                     component; Psort location: CytoplasmicMembrane, score:9.49"
                     /product="ABC transporter, ATP-binding protein"
                     /protein_id="EDN75903.1"
                     /transl_table=11
                     /translation="MEHETIISVEHVSMRFSLSSEKFDSFKEYVIKSLKKQVSYDEFWA
                     LKDVSFEVKQGDSLGLIGLNGSGKSTMLKTIAGVLKPTKGQVTVGGNIAPLIELGAGFD
                     MDLTARENVFLNGALLGYNRAQMEAQYEDIVEFSELSEFMDVPVKNFSSGMVSRLAFAI
                     ATIGIPDILIVDEVLSVGDFRFQEKCEARIQNMKDQGTTILFVSHSIEQVKKICNKVVW
                     LDHGVLKMFGDAQEICSIYEKA"
     gene            complement(20489..21265)
                     /locus_tag="RUMGNA_03527"
     CDS             complement(20489..21265)
                     /codon_start=1
                     /db_xref="InterPro:IPR013525"
                     /db_xref="InterPro:IPR013526"
                     /inference="protein motif:FPrintScan:IPR013526"
                     /inference="protein motif:HMMPfam:IPR013525"
                     /inference="similar to AA sequence:REFSEQ:ZP_00204552.1"
                     /locus_tag="RUMGNA_03527"
                     /note="COG: COG1682 ABC-type polysaccharide/polyol
                     phosphate export systems, permease component; Psort
                     location: CytoplasmicMembrane, score:10.00"
                     /product="ABC-2 type transporter"
                     /protein_id="EDN75904.1"
                     /transl_table=11
                     /translation="MSSYIQNFKKFQPLLAELVARDIKIKYRRSVLGVLWTLLNPLFMM
                     IILSVVFSSIFKFDIENFPLYILSGQLIFNFFNDATTSSMTSIIGSAALIKKVYVPKYL
                     FVIARVFSSFINLMASLVALILVMVAMRAELHWTVIFSVIPLAMIILFSLGVGMLLAAL
                     TVKFRDIMHLYSVFTTGLLYLTPVIYPMSILPESVRTVVNINPLTNMVQMFRDVMFYNT
                     LPTFSAVVLGVVEVAVALILGTYVFYKNQDEFILNI"
     gene            complement(21282..21833)
                     /gene="rfbC"
                     /locus_tag="RUMGNA_03528"
     CDS             complement(21282..21833)
                     /EC_number="5.1.3.13"
                     /codon_start=1
                     /db_xref="InterPro:IPR000888"
                     /db_xref="InterPro:IPR011051"
                     /gene="rfbC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) dTDP_sugar_isom"
                     /gene_kind="biosynthetic-additional"
                     /inference="protein motif:BlastProDom:IPR000888"
                     /inference="protein motif:Gene3D:IPR000888"
                     /inference="protein motif:HMMPanther:IPR000888"
                     /inference="protein motif:HMMPfam:IPR000888"
                     /inference="protein motif:HMMTigr:IPR000888"
                     /inference="protein motif:superfamily:IPR011051"
                     /inference="similar to AA sequence:REFSEQ:ZP_01354653.1"
                     /locus_tag="RUMGNA_03528"
                     /note="KEGG: cac:CAC2331 1.3e-67 DTDP-4-dehydrorhamnose
                     3,5-epimerase K01790; COG: COG1898 dTDP-4-dehydrorhamnose
                     3,5-epimerase and related enzymes; Psort location:
                     Cytoplasmic, score:8.87"
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="EDN75905.1"
                     /sec_met_domain="dTDP_sugar_isom (E-value: 6.2e-76,
                     bitscore: 244.5, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKIKVETCEIEGLKVITPAVFGDERGYFMETYNYNDYKEAGIDM
                     EFVQDNQSSSKKGVLRGLHFQINYPQDKLVRVVSGEVFDVAVDLRKGSKTYGQWYGVVL
                     SAENKKQFFIPKDFAHGFVVLSDSAEFAYKCTDFYHPNDEGGLAWNDPDIGIEWPIPED
                     MELTISEKDQKWGGIKELNK"
     gene            complement(21849..22733)
                     /gene="rfbA"
                     /locus_tag="RUMGNA_03529"
     CDS             complement(21849..22733)
                     /EC_number="2.7.7.24"
                     /codon_start=1
                     /db_xref="InterPro:IPR005835"
                     /db_xref="InterPro:IPR005907"
                     /gene="rfbA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 277.7; E-value:
                     1.7e-84)"
                     /gene_kind="biosynthetic-additional"
                     /inference="protein motif:HMMPfam:IPR005835"
                     /inference="protein motif:HMMTigr:IPR005907"
                     /inference="similar to AA sequence:REFSEQ:ZP_01354650.1"
                     /locus_tag="RUMGNA_03529"
                     /note="KEGG: sdy:SDY_2206 2.0e-110 rfbA;
                     glucose-1-phosphate thymidylyltransferase K00973; COG:
                     COG1209 dTDP-glucose pyrophosphorylase; Psort location:
                     Cytoplasmic, score:8.87"
                     /product="glucose-1-phosphate thymidylyltransferase"
                     /protein_id="EDN75906.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 2.5e-13, bitscore:
                     41.3, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKGIILAGGSGTRLYPLTQVTSKQLLPIYDKPMIYYPLSILMEAG
                     IREILIISTPDDTPRFEELLGDGSQFGIQLSYKVQPSPDGLAQAFLLGEEFINGESCAM
                     ILGDNIFHGHGLSKRLKVAAAKEDGATVFGYYVDDPERFGVVEFDQDGKAVSLEEKPEH
                     PKSNYAVTGLYFYDNHVVEYAKQIEPSARGELEITDLNRIYLEKGNLDVALLGQGFTWL
                     DTGTHESLVDATNFVKTVETHQNRKIACLEEIAYNNGWIDKEKLGKACELYQKNQYGRY
                     LKDVLDGKYIDQK"
     gene            complement(22815..23891)
                     /gene="rfbB"
                     /locus_tag="RUMGNA_03530"
     CDS             complement(22815..23891)
                     /EC_number="4.2.1.46"
                     /NRPS_PKS="Domain: NAD_binding_4 (5-191). E-value: 1.3e-15.
                     Score: 49.0. Matches aSDomain:
                     nrpspksdomains_RUMGNA_03530_NAD_binding_4.1"
                     /codon_start=1
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR005888"
                     /gene="rfbB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score:
                     249.5; E-value: 8.6e-76)"
                     /gene_kind="biosynthetic-additional"
                     /inference="protein motif:HMMPfam:IPR001509"
                     /inference="protein motif:HMMTigr:IPR005888"
                     /inference="similar to AA sequence:REFSEQ:YP_694937.1"
                     /locus_tag="RUMGNA_03530"
                     /note="KEGG: cpf:CPF_0482 2.5e-135 rfbB; dTDP-glucose
                     4,6-dehydratase K01710; COG: COG1088 dTDP-D-glucose
                     4,6-dehydratase; Psort location: Cytoplasmic, score:8.87"
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="EDN75907.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 1.9e-16, bitscore:
                     50.6, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 2e-17, bitscore:
                     53.8, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 5.7e-16, bitscore:
                     49.0, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTYLVTGGAGFIGSNYIHYMFKKYDNEIRIINVDKLTYAGNLEN
                     LKDIEDRENYTFVKADICDADAINKIFEENEIDRVVHFAAESHVDRSIKNPDVFVKTNV
                     LGTLVMLNAAKAAWELPDGTFKEGKKFLHVSTDEVYGSLEEEGEYFYETTPYDPHSPYS
                     ASKASSDMLVKSYMDTYKFPANITNCSNNYGPYQFPEKLIPLIINNALQGKNLPVYGDG
                     KNVRDWLYVEDHAKGIDMVQEKGRLFETYNIGGHNEKQNIQIIHIILDTLQEMLPEGDP
                     RKELVSEKLITYVEDRKGHDRRYAIAPDKIKEEVGWYPETMFEDGIRLTIKWFFENEEW
                     MKNVTSGDYQKYYEEMYK"
     aSDomain        complement(23319..23876)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_RUMGNA_03530_NAD_binding_4.1"
                     /evalue="1.30E-15"
                     /label="RUMGNA_03530_NAD_binding_4.1"
                     /locus_tag="RUMGNA_03530"
                     /protein_end="191"
                     /protein_start="5"
                     /score="49.0"
                     /tool="antismash"
                     /translation="VTGGAGFIGSNYIHYMFKKYDNEIRIINVDKLTYAGNLENLKDIE
                     DRENYTFVKADICDADAINKIFEENEIDRVVHFAAESHVDRSIKNPDVFVKTNVLGTLV
                     MLNAAKAAWELPDGTFKEGKKFLHVSTDEVYGSLEEEGEYFYETTPYDPHSPYSASKAS
                     SDMLVKSYMDTYKFPANITNCSN"
     gene            complement(24057..27995)
                     /locus_tag="RUMGNA_03531"
     CDS             complement(24057..27995)
                     /EC_number="3.5.1.28"
                     /codon_start=1
                     /db_xref="InterPro:IPR002198"
                     /db_xref="InterPro:IPR002508"
                     /db_xref="InterPro:IPR013688"
                     /inference="protein motif:HMMPfam:IPR002508"
                     /inference="protein motif:HMMPfam:IPR013688"
                     /inference="protein motif:HMMSmart:IPR002508"
                     /inference="protein motif:ScanRegExp:IPR002198"
                     /inference="similar to AA sequence:REFSEQ:YP_001034836.1"
                     /locus_tag="RUMGNA_03531"
                     /note="KEGG: bce:BC2207 7.7e-20 sporulation-specific
                     N-acetylmuramoyl-L-alanine amidase K01448; COG: NOG18564
                     non supervised orthologous group"
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="EDN75908.1"
                     /transl_table=11
                     /translation="MKKVQKVLTLLLVFMMVFTTAGMNVAAAGEMDSVAGEADIQSQEQ
                     QQTLDETDTQQETTQQPLEGILEYVYVDEAVVNMPQTQNIAVGFSDESLVLESAVLHYS
                     SVVTGEQFEMPASAIVNNTVLFTQDYPEGSAEDVYQLDSLTYQSSGVSSTVNLLDEEID
                     AGYTVTVQPEEENSSEEAVPDVAVYSLSEDGNVIEASSDTENIEETVAGVLEEADPVSP
                     LAREARANKTVVICAGHDATHTGASGNGLKEEELTFKVAQYCKQALEQYQGVTVYMDRD
                     SISCKYPGQNTSYCLNQRIKDAAALGATVFVDIHFNTGGGTGAEVYYPNKSYNEGIHQE
                     GQNLANKILSELSALGLRNRGAKIKDGTTGETDPNGNKDDYFTTNYLSKQYGMTGVIVE
                     HAFLDSASDAAKLKDENFLKKLGEADAAGIAATYGFSKGNNGNEQATVQIKNKNDFNGT
                     AQIEVSGVGAGAQIAVWSDDNGQDDLKWYSVSGNSGTVNFDIKNHKKSAGTYNVHVYNS
                     SSTKILCNTTFRVSKDTSAKLKVSAVDGRQDLYRVKLSFADMPDEVSGVQFPVWSKGDQ
                     SDIRWITAQKTSSGVWEADVSISGYQIGDIYQVHAYASLTNGKQVFIGNSTFKVVGPSA
                     DVTIKNYSAENGTFDVVVENIVAPAGVKEVQVPVWSLRGQSDIVWYRAEKQSDGTYKVG
                     VDIANHKNNTGTYNIHIYILGNDGSQTMVASTTQKVEASAVEITAKDETGKESQYELTA
                     KNVRNADQVRFAVWSDVNGQDDLIWYDAKKKSSTWSTEISIVNHKTAGVYNVHVYSTVG
                     KKQTLIGNTTFKVSSPTGTLEVKNYSESKGSFEVILKNVTSKSGVNAVYIPVWSESNQS
                     DIVWYQADKQSDGSYKVIVKTKNHNQNTIYNIHAYVTAKNGIMQFVDGTSKDVSKMEPK
                     VSISNADGKEKKYTATIENANALGKVSSVQFAVWSDTNGQDDLIWYQGTQKNADAWSTE
                     IEISNHKTAGSYNVHVYGMIDGVQKFLVADTFEVSKPKGTIEVKNYNAAKGTFDVVVKN
                     VSSKSGVQEVQIPVWSKEDQSDIVWYSAEKQGDGTYKAEVELSRHQNNKGTYNIHVYIL
                     TETSIYAFVAGTTYEVSGNSSEQNTENLTPIMGESTTTVEQMMRYYESTGNQYPAEALG
                     KGGAPTLRDFCQIYYDEATAEGVKAEVAFAQAMKESAWLKFGGIVKIEQFNFAGLGALD
                     GNSQGQAASFPDVRTGIRAQIQHLKAYASSEALKNACVDPRFKYVTRNSAPYVEWLGIK
                     ENPSGTGWASSKNYGYQIVNMMDVLKNK"
     gene            complement(28046..28981)
                     /locus_tag="RUMGNA_03532"
     CDS             complement(28046..28981)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /db_xref="InterPro:IPR001173"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123:polyprenol-monophosphomannose synthase ppm1
                     (Score: 204; E-value: 6e-62)"
                     /gene_kind="biosynthetic-additional"
                     /inference="protein motif:HMMPfam:IPR001173"
                     /inference="similar to AA sequence:REFSEQ:ZP_01353599.1"
                     /locus_tag="RUMGNA_03532"
                     /note="KEGG: lsa:LSA1519 2.1e-99 putative teichoic
                     acid/polysaccharide glycosyl transferase, family 2 K00754;
                     COG: COG0463 Glycosyltransferases involved in cell wall
                     biogenesis; Psort location: CytoplasmicMembrane,
                     score:9.97"
                     /product="glycosyltransferase, group 2 family protein"
                     /protein_id="EDN75909.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 2.5e-38,
                     bitscore: 122.3, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKISVVVSCYNEEESIPLFYNEIKKVMEIMKEFQFEVLFVDDGS
                     KDRTLEVAKELAKKDECIKYVSFSRNFGKEAAMYAGLSYASGDYVTIMDADLQDPPRLL
                     PEMMHYIKEEGYDSVATRRVTRKGEPKIRSFFARRFYHLIKKISDTEIVDGARDYRLMT
                     RQFVNSLLELEEYNRFSKGLYGWVGYKTKWMEYENIERVAGETKWSFWKLFVYAIEGIV
                     AFSTVPLLISAIMGIVLCVLAFILIIVIVAKTLIFGDPTSGWPSMVCIMLFIGGIQLFC
                     IGILGEYFAKAYMELKKRPIFICKETNIQP"
     gene            complement(29051..30703)
                     /locus_tag="RUMGNA_03533"
     CDS             complement(29051..30703)
                     /EC_number="3.1.6.-"
                     /codon_start=1
                     /db_xref="InterPro:IPR000917"
                     /inference="protein motif:HMMPfam:IPR000917"
                     /inference="similar to AA sequence:INSD:EDK25062.1"
                     /locus_tag="RUMGNA_03533"
                     /note="KEGG: csa:Csal_0010 2.6e-37
                     phosphatidylglycerol--membrane-oligosaccharide
                     glycerophosphotransferase K01002; COG: COG1368
                     Phosphoglycerol transferase and related proteins, alkaline
                     phosphatase superfamily; Psort location:
                     CytoplasmicMembrane, score:7.63"
                     /product="arylsulfatase"
                     /protein_id="EDN75910.1"
                     /transl_table=11
                     /translation="MQELKKKHRKKPKKELDRGAQKEQKNLTDITEEQLKVNIGIVRLG
                     NMIKVIQIVMKVLLCMLAVLFSFLAILLHEAANWMLATWTNLSMEELVAQLKTPIQGTS
                     HEVLWDFVETCIPAAVMAVFFVVLVIVMVRKTKITKWVVQIGAVAGSMALIVSSGQMVW
                     NELDVGEYLENQDTISMFLQENYMDPALVPVTFPEQKRNLVYIFMESMESTYASTDVGG
                     AFAENDIPEMTQLAMENVNFSTGDMLGGLIPSDGATWTMGAMVAQTSGLPLKVKLRAEN
                     IQEDVQVLPGATVLGDMLAVQGYKQVVMFGSEGEFAGRKQYFEGHGNYEVKDLLYAQQN
                     GLIPPDYRVWWGYEDHKLYDFARREVTNLANSGQPFNFTMLTVDTHFEDGYVCDLCQDE
                     HPGNQYANVMSCASRQVVDFVNWLKAQPFYENTTIVIVGDHLTMDSDFCQDVPEDYTRG
                     VYNTIINAPIVPVNQKNRMATTMDMFPTTIAALGAQIEGDRLGLGTNLFSAEPALAEKV
                     GMDTLNKEIRKRSIFYEQIAGKENIDDSVMDMK"
     gene            complement(30805..31758)
                     /locus_tag="RUMGNA_03534"
     CDS             complement(30805..31758)
                     /codon_start=1
                     /db_xref="InterPro:IPR005835"
                     /inference="protein motif:HMMPfam:IPR005835"
                     /inference="similar to AA sequence:INSD:EDK25064.1"
                     /locus_tag="RUMGNA_03534"
                     /note="KEGG: xfa:XF2432 1.9e-06 UTP-glucose-1-phosphate
                     uridylyltransferase K00963; COG: NOG09722 non supervised
                     orthologous group; Psort location: Cytoplasmic, score:8.87"
                     /product="hypothetical protein"
                     /protein_id="EDN75911.1"
                     /transl_table=11
                     /translation="MDWENKGYRAKEKNMNKATLVVMAAGIGSRFGGGIKQLEPVGPNG
                     EIIMDYSIYDAMEAGFDKVVFVIRKDLKKDFKEVIGNRIEKVVEVAYAYQEVDDIPQAY
                     RERFSGRTKPWGTGQAILCCKDVVDSPFLVINADDYYGKQAYVEAYEYLTRETTSKDEI
                     CMVSFVLKNTLSDNGGVTRGVCKVNENGYLADIVETSNIEKYESGAAVHKGEAYIPIDI
                     ESSVSMNMWGLTPEFFQILESGFEAFVANTPADNLKAEYLLPTIIGDLLAEKKLAVKVL
                     TSKDKWFGVTYKEDKDSVVSELQALIHAGVYPKKLF"
ORIGIN
        1 ttataaatct ataaaatcta catcataact gtctttttct tcacgagcag acgatcttcg
       61 ttttggctga tactccggaa catcatcctc ttcttcgtca tcatcatagt cctcatactc
      121 atcgtattcg tcgtcataat catcatcttc atactcgtca tcgtcgtact cttcaaaatc
      181 atcctcatat tcatccgaat cgtcctcgta tgtgtcgtaa tcatcttccc catattcgtc
      241 atcatcttcg tactcttcgt attcatcagg atcttcgtca tctgtttcct cttcgtcttc
      301 gaagtcatct acaaaatcat cctcttcgtc ctgatatcct ttgaactgtt tacgagattt
      361 tttctcaaca actgcacgac ttccttttga attcccgatg gattcatgct catcgtagaa
      421 ttcatcaagt tcttcatttc ttctgcgtaa tttcacgccg actacaataa taatgatgat
      481 caaaattaaa ataaccgccc aggctgctgc tacaacaatc agcacctgat cctgaagaaa
      541 gttttttact ttatctatca gtgttgtcga agaacttgta ctcttttctt ttacatctgt
      601 gactggatat ctctggtacg tttcatcctt tgtatcatac tggtagaacg attcctctcc
      661 tgattcgttc atcgcataca tcagataaaa gtcctcactc tctgaattct gccataccgg
      721 gaaagtcagt gtgccgactg tcagttttgt tttcttaaac tgagacggca gtccttttcc
      781 atcatttgtt cccaacaaaa agatataact ggaatctgta atcgacacca tctctgtaat
      841 cgcaaatgag ttatcttttt cattgtaaag tgccatcact gggtctttgt ctccctcaac
      901 cagatacaca aaatactttc cggaagtttc ctgcaaaatc gcgtttacag tttctccgtt
      961 atactccatc gtagttctgc tgcatccgtc cggaacaagc gcgtcggaaa aatcattgta
     1021 aattgtgtat gtgactccgt cgatctctac acttcccgtt cctgtggcca ccgcagtggt
     1081 ccctgctgag ctctctgacg atgttccgtc ccctgcctcc acggtaactg tggaatcacc
     1141 tgttgtcaga tttaaagttt catcagaata cagataagag gtataatctg acacctccag
     1201 ctttgttgct ccttctttca gcgctttaaa gaccatggta tactccagct ctgaaacagt
     1261 tccatccccg gtagcctcca gcttcaccgt tccgtcccca ccggttgcat tggttccgct
     1321 gacaaactcc agtgctgctt tgtcatatgt tactgtgaca aaaccatccc cgattgcttc
     1381 tccaccagta ctgatcttag ctttgactgt aacatcctct cctacttttg ctgtaggatc
     1441 cgaaaactga aacgttcctt ctgccgcatg tacagacact gaaggataca gcatcagaaa
     1501 gcacactgca aacaaaagaa tccctatctt tttcaacgac ttcatgtaca tctcctcttt
     1561 cctgtctctc gacttttctt cgtataaata aaaactgttt ttcccttatt ctaagctctc
     1621 tccaccggta tcaccactgt cgccggttcc ggtatccggt atctgggaat tactgtcgct
     1681 gcttccactg tctgtaccgc cgccatctga cggaggtaca taatcaccgc cggtatcttc
     1741 tgtataccca ttaccagagc tgccatctcc atagccactg tcctgatatc cgccagttcc
     1801 ataactgtta tctgtgtagc cgctgtcata tccggaataa tcctgagaat atccatactc
     1861 atcatattct gtatcgtaag attctcccgt atcatacgtg gagttggaaa tatcctcact
     1921 gatactttgt accgtagaag acggtgtata atcgttctct ccaaataaga actggtgcag
     1981 cttcgtcaca tcggatgcca gatctgtcgc tacaacagaa tttccaacat caagatcagc
     2041 cgttgtactt tcatacggaa atccctgcgt ctctccaaat atataagact tcacgtcttt
     2101 tgcataagca atcgtctccg tcagtgtaaa attcgtcttc acgttgtcaa acactttatc
     2161 aatgatcttg ttgatcgtgg aaagttttgc tttctgcgct tttatcgcaa tctgctccag
     2221 tacttgccgc tgtctctctg ttcgcttata atcgtcaccg ccgccgtatc tgagacgggc
     2281 ataagccgtt gcctgtactc cattcaaatg ctgctgtcct aactgcgtaa acggagctga
     2341 atccactcct gtatttttaa tcacttctac aacatagttg ttcagatacg gaatgatgtc
     2401 catgccattt tccgcttctt ctacattaat atcaattccg ccaagggcat ctatcacatg
     2461 aactaaaacg gaaaaatcca ctgacacata gtgctcaata ttcagatcca gattcttatt
     2521 gagcatagca accgcttctt cttcaccgcc gtaagcatat gctgcattcg ctttattgta
     2581 agttccatct gaaagctgca gaagcgtatc tctgtacaca gaaaccagct tgatttcctt
     2641 tgtctcacgg ttcagagacg ccaccataat cgtatcactt cgggatccca tctcctcatc
     2701 tgtctcacgc gtatccagac caaacagtgc aacagtcagg taaccggtac cgctgatctc
     2761 tgcttcctcc gaaatcgcaa gcttatccgg atttaatgca acaccgccaa tttttcccca
     2821 ttttgccgca accactgcaa cggttgctgt aatcagcagg atcagaaccc ccatcagaat
     2881 cgccactgct tttttccctg tagaccagga tgcaaatcct ctctttgccc gctttctcga
     2941 acgccccttc tgtgaaggtc ttccgttcgc agaccgcctt ccattggcag aagtgctgcc
     3001 ggacggtcgt tttctctggg cggaccgctg tctctgcgtt ttgtccctgt cgtctcccat
     3061 ctgatttctt tgctccggac ggcggcgcgg ctgccccgac ctctgagaac ttcttctgtc
     3121 cgctccggac attactgctc tcgaacgcct tcttgtatct cccataattc tatcctttct
     3181 catggcatac atcatagatt gcctaaaata tgcactttaa catcatacaa tattttcctt
     3241 caaacatcaa tgaaaaaact gtgaatttca agtttctctc cagtatcgtg gattcatcgt
     3301 acatttcaaa atcagccacc ggggcagttt cttataattt ttccccagtt tatatcctat
     3361 gtacttccac ccgctcttgc atacaagaga taccagaagc catggtctgc ccgacttcaa
     3421 cagatatttt gctgtatcct tcaccagacg tatcccttct ccttcagaag gtactccttc
     3481 aaaaatctcc ggatgatctg cctgtgagac cgccaggtca aaattccggt gaaactgctg
     3541 tctgcagtta taattgtgag aatggatcac ttttgcatct gccgcataat aaatcttcca
     3601 tcccgcctga atcatcctgc ctgccaggat catgtcttca ttgaaaatcg tttttcgtac
     3661 aaatcctcca agcctttcgt atacatcctt ttggtatgct gcacagacat tagagcagaa
     3721 ataggttttg attcccagtt tggaaagatc ttctttggat ttcaatctgc tggttttcgg
     3781 ataattaaat tctcttgtat agcgctcaat aaactgacaa tccgctgccg gcagctgtct
     3841 tgcataaact gctgctacgt tttcatacga aaatccgtaa agcagacgct cgatcagaaa
     3901 ttgatccgcc ggcatagcat cctgggtcat gtagacaaga atctccgcat ctgacatctc
     3961 agctcccaga tttctcgtac caccgtgatc aaactcttcc ggcagaatcc ggtggatctt
     4021 gactctgtca gaaatcgtat acaactcttt tggaaagatc ccgctctctg tatcgatcag
     4081 atagatccga ttgacctgaa cactctggct taacagacgt tttaccagct gtacgcatct
     4141 ctgatccggc ttatacgtag ggatcagcac atccactgtt ctatttcctt ccatgtgaac
     4201 cttttccttt cctgcgatat ccgacaaacc agtacatcat caaagtcagt gccagccaga
     4261 accaggtcgt cggattactg aaccaggtcg taaaaaaggc aagccccaga taaatcgcaa
     4321 tctgtccata aaacatatac gtcatcggat ttttcttctg acgcaccgga attgaaactg
     4381 ctgctgcagt cagaccgatt ataaacgcaa acaaagcggt tccgatgatt ccaaaatcat
     4441 agtaggcatc ataaaacatc gttaacgtcg taagctctgt ttttgtgaca aaatccggaa
     4501 ttgtcaccag ctgtggaaat acaaatttca atcccgtcag tgcaaaaaac ggaaacagca
     4561 tctgcagtcc ccatgtgtgc gctgtcaact gctctaccat acagttaaaa ttctcaaaat
     4621 tattggctac ataaatataa ggctgtgtaa taaaaatcgg cattttggaa tttttcatct
     4681 caaaaattcc atttaaataa gtcacattat gccgtcttgc aactgtcaga agtacataca
     4741 ctggaatcat gatcaataaa cctgtgacga tcatcttcca tgtgattttt ttatacaaca
     4801 tcagatacat cactgccgca aagccaaccg caaacaacag ctgaaatctg gagacacata
     4861 aaataggaat cgccactgcc gtcaggtttc ctgcaattaa aagtatccat gtcctgaccg
     4921 aaattttttc tgtaaccttg gtatacaata cagtcagtgc cggaatcaaa atgcagctga
     4981 ttgtaaaata gtgcactccc gaaatatgaa aataagaata tgcatgaggc gctgaattga
     5041 acaatggaat ataacctacc accactgcct ccaacgtaaa acatgcaatg gaagctgcca
     5101 tcagtccgaa gatgcagatc agaatccgct ttgccgagat ctcatctctt tttacttcct
     5161 gcctctgttc tttcgaaaaa cggccaagcc agagatcata tcccagattg aaacacacat
     5221 agatcagaaa aaaggtcagc catgtcacat tgctccagtc actctgcagc ctgctgagct
     5281 tcaggcatgc gatgccttct ccgcctaccc atgccagcgt aaaaagcccc cgcatatcca
     5341 caagattttt tgtctttcta aaattccata taaacaaaaa cattgcctct gccatcagaa
     5401 gtactgcagt cacataatcc agatgtgcct ttgcagccaa taccgctgcc gcataaacta
     5461 aagtataaga actatattcg atttttctgt ctgcgatcat ttttcgtaac attcttttcc
     5521 tctttcgcta ctgtgcataa ttttccggat aaacccccgt cagataagcc acatcctgac
     5581 tgatctgctg tacttcgtcc gaaggctggt atccagtctc tccaaaaagc tgctcatgga
     5641 gctgtcttac attgtccgca tgtccgatcg caaccgcata agagccttcc agtccaatga
     5701 cattttcact ggtcgtaata tcaaacggaa agccttttgt ctctccaatt ttgtatcgga
     5761 atatattcag tcccagtttc atgatatccg gtgtcgtcat attcgttgat atttccggca
     5821 gtacctgatc cagaatctta ttccatttta ccggtcctgc tgtcttcagc ttctgaatca
     5881 tcttctgcaa tatgattctc tggcgctctg cacgcttaaa gtcatctccg gctgtataac
     5941 ggatcctggt ataggaaact gcctgtattc catccagatt gtgaactccc ggagaattct
     6001 catccagggt atgtgtctgc cgtcctacca cctgtgaggt ttctgccgta tatccattca
     6061 gccagaatat ttcctcactg gtcagctcta cttccacccc acccaggata tctatgatat
     6121 ctgcaagcga attgaaattt acagaagcat attttgtaat atccagatcc aggttccggt
     6181 tgagcattgc cactgcctcc tgcggacctc caaaggaata cgccgcattt gctttctcat
     6241 aagaaccatc ctgctgcttt agcagcgtat cccgatatac ggaaatgatc tttacatctc
     6301 cggtcttatt gttgatgctg acaatcataa tactgtcact tctcacgccg ccacttagct
     6361 ctccgtctct ggaatccaac ccgaacaatg ccacattcgt gtatcccttc ggtgtctcat
     6421 gtagttccag gctgctctca tccagtgtat tatggttgag atgatccagc ttgtacatca
     6481 taaatgccgc caaaacaaga accgcaagta tcagaaattc caggaccaaa aacaggattc
     6541 cccgcctttg tcttttttta ttcaatcgtt ttctctgctg cagcgatatt cgctctcttc
     6601 tgcgaaacat agatccgcct ccgtcttagt atgcgttttt gttgataaag cctttcagaa
     6661 acgtcagcag gataatctta aaatccagtc ccaacgtcca gttttcaata taatacaggt
     6721 cacactcaat ccgcttccgg atcgaagtat ctccacgata gccattcacc tgtgcccatc
     6781 cggtcagtcc cggacgcacc tgatgcttga tcatatatct tgggatttcc tccttaaact
     6841 tttctacaaa cagtggtctc tccggcctcg gaccaaccag gctcatatct cctttgagca
     6901 cattgaatag ctgtggaagc tcatcaatgc tggtcttccg gataaatttt cctaccggag
     6961 tcactctcgg atcatctttt gtcgtccagc ccttcttctc ttcgctctct ttctgtacga
     7021 tcatggaacg gaacttatac atgtagaacg gcttgttctg cagcccgatc cgctcctgtt
     7081 taaaaatcag cggtcccggt gcagtcaact tgatcagcac agatacaacc agcatcacag
     7141 gtgaaaaaag aatgatcgca acgatcgcac caaaaatgtc tactgcgcgc ttcacaaact
     7201 tattcaaagc attattaagc ggtacatgac ggatgttgat cactggaagt ccctggatat
     7261 cttctgtata tggttttgtc ggaatgatat tgttataatc cggaataaac tttgtatgca
     7321 cacctgattt ttcacacata tttacaatat attccagctt gtgatactca tccagtccca
     7381 gtgtgatcgc aatctcatcg atctgattct gcggaagaat gaccagcaga ttgtcgatac
     7441 tcccgatcac cttgatccct ttatactcca ttcctctcgg ctggtggtca tccagaattc
     7501 cccgcacggc atatccccac tccgggtttg caagaatccg gtcaatatac tgctctgccg
     7561 cgcggctgta gccaaccaga atcatatgtt tctgattata tccgttcttt ctcgccttgc
     7621 gcaaaaccat cctcaccata tttctggcga atacttccat ggtaatattg acaaagcaga
     7681 aaataaatac tacccatctg gaatatctgt ctgaaagctt tgcaaggaaa aataccatgg
     7741 tcacacccat caggccgatc acattcgcct gtactacatg ccaggcttcc agccttcttc
     7801 cctgtacccg cttcggcgtg tagagctgaa atgcgtaata caggatcaaa taggacggca
     7861 ccagaaagaa cagtaccttc atatactctc tcagtgacag ataccatgga tccaggtcaa
     7921 ataatccgct ccgaaaacgg atataccagg acagcacata tgctacaatg atcactcctg
     7981 catccagcac aacctgaatg cggtttaata atttctgatt ttcttttatc ataatacgac
     8041 cttccgttat cttacttata aaaacacatt atctatgata taatacaata ctttatttca
     8101 atggacaagc acaaacttga ttttaacagt attttattca tttttccgta atattttcgt
     8161 aatttttaat aaacatatgt ttgtatagaa aaacagaacc gaatttgata taatacattc
     8221 gcgaaataaa ttacagcagt aatagaaatg aggagcacat gaaagttact atcattattc
     8281 ccaattataa cggaaaacat tttatggagc cctgtctggc ttctttaaat gaacagactt
     8341 gccgggattt caagatcctg atcgtggaca atgcctccac ggacggaagt ctggaatata
     8401 tggaacagac ttaccctgat atcgaagtgc tggccctgga ttctaactat ggattcagcc
     8461 gtgcggtcaa tgaagggata cgtcacgcag ataccccgta cgtcattctt ttaaacaatg
     8521 atacaaccgt ggattctcgc tatgtcgaag agatgatccg ggcgatcgag gtctctgacc
     8581 ggattttttc tgtgagcagc aagatgatcc agatgtatca ccccgatctg atcgacagcg
     8641 caggagatct ctataccttg atgggctggg gggtatgccg gggagccgga cgaccggttt
     8701 cgaattacac cgaagatgat acggtattta cggcctgtgc cggagctgct atctacagac
     8761 gaagcgtgtt tgataaaatc ggcttctttg acgaaagcca ttttgcctat ctggaagata
     8821 tcgatgttgg ttaccgtgcc atgatctacg gctataaaaa ccggttctgc gcttccgctc
     8881 ttgtgtacca cgtcggaagc ggaacgagcg gttccaaata taacactttt aaagtgaaac
     8941 tatccgcccg caacagtgtc tggctgaatt acaaaaatat gccgcttttg cagctgatcc
     9001 tgaatttcat cccattactt ttgggatatc tggtgaaata tttatttttc tgcaaaatcg
     9061 gatttggaac agattacaaa aacggaatca aagaaggaat ccatggtctg tccaaatgcc
     9121 gcaaggttcc gtttcggatg gagcatctag gcagctatat ccggatcgaa tttgccctga
     9181 tacgccacac attcggttat gcggccgact ggctgaaaag aaaattattg cataaataga
     9241 aaacacagga aggaaagaga cttctgtcat ctctttcctt cctgtttatc ttttcttata
     9301 ccatctggca aattttctta caaattgtga tttccaatac ttaatatttt cttccgggag
     9361 aagaacacgg gtttcatatg gggctgtaat ccatgcttct acctcttttt gcatactacg
     9421 tcctaataca ggcaaatgca tttcttcacg caacgcctgt gcatagtctg tatctgaaag
     9481 gatcagactt ctctttagca tggtaagact ttgaatccca atctgtatgt ttgttcctat
     9541 atagtcaagt tctgccgtct cacaaaatat ttttttcaat gttgatattg agcccggaag
     9601 taatttatat ttatttaaat cccctaattt ttggagataa tccagatttt tcctatcttt
     9661 gatccagata tacactgttt cgtactcttc ccttaacata ttcaacattc tgctgtcttc
     9721 ttccctgcaa tcttttttct cttccaagac tactaacact tcttttcctt tttctttagg
     9781 gatttttttg catctctgtg ctgtcagact ccataaagac ggacatcccg tccgtatcac
     9841 attatgaatt cctatctgct ccagaaaata tcttgtcttc tcatcacgaa ctgcatgaac
     9901 tcctttggaa gataacagaa agtgaagtac attctgtgta taatcactaa tctgatcacc
     9961 ttctgtaaaa tcacacacac ctgctcccat aagataaatt ccctgatatt ccatcaattg
    10021 ttctaaaagc aaaagctgtc ctgatttttc catctgtttt gaaagcacat ttgcaccaca
    10081 taaaattttt ctgctcccag ttagttctcc tgcacttttt ttacaataat atggtggcac
    10141 acaaataagc ggtctgtcca aaaataaatc tctacatatc tctccacttt ctttcatcac
    10201 cattttatct tcaaaataat ttgtcctgtc tgctatatca aaaaatacta ttttatcatc
    10261 agaaaatttg aatttttttg aatctttcat tatttgaatt tgatgaatcc gttctttttc
    10321 gatttgactg gatacttctc cttgaaaata ttcatgtagc tttggagtta ttatttcata
    10381 taaatcgatc tctgggacta tctgcacttt attttggaaa agctgttcca gatatcttat
    10441 atagtcatca aacttcagtt tatcttctat ccatgctttt gcacccgtca acacttcttc
    10501 ccgtctctcg ctcaaaagct gttttgtcac tttcgccatt tcctcaacat caaactcaga
    10561 aatcaaattt cctctgcctt cgtccagcat tgtattgacc ccaccagaat tcttaaatgc
    10621 tactaccgga atttcatact tcattgcctc caataccacc gatggaaatg gatcctctct
    10681 tgatgtaagc cagaatacat ctgcatgtct caacaattca tgatattttt gtttatcttt
    10741 aataaacgga ataaaatgaa cttttccttc taggttcgat tgacgaatct gattataaat
    10801 ccatccttcc aaaatcggat ccgaaaattt tcctgtccat acaaagtgga cttcctctgt
    10861 tttttctttt cgagaaagaa tctgtgctgc tgatacaaat aaatctgttc ccttcctcaa
    10921 ttcacacgtt cctgagcaca tgacaatttt ttgatccaat gaaaaaccat attcttcaaa
    10981 tgagaacctt gaatccccct cttcgtcaac ctgcatatac acaccctgag gccgaatcga
    11041 acatttcccc ctgatcactg gaaaaagagt ctcaaatccc ttctgtacac tataatcggg
    11101 aaatacaatg tagtcagagt aatatgcaat cgactcacct ggagatagaa atccatacaa
    11161 ctctatcgtt gtcttcatct catgtatcaa agaaacaata aaaaatccat actgttttaa
    11221 aagaggaaca tacttccctg acacaacagt attcgtaatc actcgacaaa atccctcttc
    11281 tctcaaaagc tgcattaaat gctccagata ttcttcggcc tcccagtttt ttgactctcc
    11341 ttttgtacca caccagccga ctgatatctg atttctcgca ttatcatgca aatagaatat
    11401 aggaatctct ttttctgcat acttttcttc taaaaatcca tccccatgat tcgcagccaa
    11461 taccacaaca tctcgaccat tttctttcag cttttccgca atatgatatg ccaaaagcgg
    11521 tgctcctgta ttactcatat catgagtcaa tactgctatc ttttcttttc tgccaagttg
    11581 tcccatattt tcttttaatg cattcagagc attttcagaa gatgctgaag caatttccaa
    11641 tttttctatt ttcacaacaa cattttgatc tgataagtcc aatcgaactg cctctgccgg
    11701 ataaggaaaa tagatttctt tctctatatg cctattcaaa tatagtggaa agtggtatgc
    11761 ttgtttttca ctaaatacct cgccttttcc tttataatac agcacagcat tcaaagcttc
    11821 tattccttca atacaaagaa aaaaggataa acgaacgccc atcactgatt ccgtaaaata
    11881 aacatgaagc tgtggatcct gttcctgtaa ctcccacata ttgccggtct gctccatgtt
    11941 tacataggat ctgcatgctt cgttttctat acttattcca tctcttttca tccccctgta
    12001 cctccccgct gattttttct tattgtacca tattcttctg tagaaaaaaa agacaagatt
    12061 ccttaaatcc tgccttttat cttttgttgt ttaagaaaat cttgtcatat aacccggata
    12121 ctccgcgtgt cctgtggcaa gcatttctcc gtttactgta atgtgaattt ttgcacaatg
    12181 gtaaacatcc aaatacgtgt tgcagatgct tccaatcacc agatattctg cggaagatcc
    12241 catctcttta atgtaagttc caaacttttc ggagagatcc agatcaatga cctgttctcc
    12301 atccttttct ttctttgtaa aacttagaac tgtggtatcc gatggaagaa ctccggctgc
    12361 tgccaactga gaaaggacag tttccggtgt gattgcctca agtgaaacct cttttttatc
    12421 aaagccggat acatccttgt tctgggcata cacagtaatt gttcctgctc ccagattatt
    12481 tgcatcctgt gtgttttctg tctgctcctg ctgtgtctgg tcttgttcat tctgtccgtc
    12541 ctgattgaca tcctgatcag atgtgtcatt gtcctgatcc tctttctgct cttcctgtgt
    12601 tgcattttgt tccggagttg attctgttgt ttttccacag gctgtaattc caaacatcag
    12661 cacaaccact gtcaaaattc ccaatacata ttttttcttc atactcccat tcccccctta
    12721 acgtatttct gacagatatc ttttcaaggc atcctgccag gtcggaagcg gcgtgaagcc
    12781 gtttttcttc agtttagatt tgtccattct gctgttgtga gggcgttttg cctttgccgg
    12841 aaatttgtcg cttgtcaccg gaactacatt gacatccatt cctgcctgcg caaaaatctc
    12901 ttttgcaaat tcataccagg tgatatatcc cccttcattt gtcacgtgat attttccata
    12961 agcatctttt tccagcatat ccacaagcag tctggcaaga tcataagtat acgtcggagt
    13021 tcctacctga tcatccacaa ctgtcagagt atcatgtgtc tctcccagat tcagcatggt
    13081 cttgataaaa ttctttccat tcacaccaaa gacccacgcg atacgaacaa tataatattt
    13141 gtccaagaga cgttccacag cctgttctcc ctcatatttg gtctgtccgt aaatattcag
    13201 tggctgtgtt acgttatcat ccggctccca cggacgtgtt ccttctccct cgaacacgta
    13261 atctgtactg atatagatca tcgggatatc aagtgcctta catacttttg caatattctc
    13321 agtaccttca gcattgactt ttctgcacat ttcttcattg tcttccgctg catctactgc
    13381 cgtccatgct gcacagtgaa caacgctgtc tacctttgcc tcacgaatga cagaatctac
    13441 tgctgctgca tctgtgatgt ccatctcttc aacatctaca ccaacacctt catatcctct
    13501 ctttgcaagc tcgttcatga catcatgtcc aagctgacct tttactcctg ttactaacgc
    13561 tctcatagat tgtcctcctt cgcagtctat ctattttctg ttcttttcct tataagatac
    13621 atcattcaat gcatactgtc cagcattaac tgtgttttct ccctcttgca tctagccata
    13681 taccaacttc tcgaattcct cctgcagccg tcggaatcaa caaaataaag tatgtccaaa
    13741 tatactgtga ttttgcttcc cacaatatat gaaagaaaaa tccaccaaga actgttgtca
    13801 ataataataa ttctcctaat tccatctgct tccttctctt ccatattcca attcctgcca
    13861 tactcaaaat caaaaagtga atcacatcaa accatttata aagaattttt cctgttcttc
    13921 cataataaaa agaggctgca atttttgaaa tcccatctgg atgctgatcc ggctgatgat
    13981 tgctaatcca caatgcctca aaactcggtt cattccattg tgaaacaatc ttgtgataat
    14041 aaaactcaac tgctactttt ttattttcac taaatccttt cagagattct tgaatatggt
    14101 ttaatgctac ttctccctct gttttccctg tttcactcgc ctcattcatc atatcgatca
    14161 aagacacgtc ataccagcct tctgcaagag gacctttttg cattcccatt gcgatccaga
    14221 gcaatttgga tgctcctttc tccaactcta tccctgaacg tgcggaataa tatttttcca
    14281 atcctgcctg tgctccaaag cttagactga acattaacac aatacagagt aaattccatc
    14341 ctttttttga tttcatgcag tctacgaaca gtactgctgc catagcaatc attgccacct
    14401 gataattgct tttcactaat accgccagta cagcgcatac tacaaacgcc actgcatatc
    14461 tgagttttcg attttcaaaa tgttccaaaa ggaatacaaa cccaagaaga gaaagtgcca
    14521 gccctatcag atttccatat acaaatgttg tataaaaaat cggaacacaa aacataaaca
    14581 atataaccac tgtaattcgc tctgccgtct ctgttttgaa aatttttttt gacaacttca
    14641 acaaacatcc atatacaaca cacaatgtca atacgtttaa catctgataa accagataat
    14701 ttcctgctcc aaaaagccga tatatctgtt ccaacagcca gataatcccc aactgatgta
    14761 catactgata tacatatccg cctttctgga gcatcgaata atcattattc aaaaactgca
    14821 ctgcggcgtt ggaaaccatc atatcatctg caaccggaac cggacgagtc agaaaaatcc
    14881 atccaagtga taataccagc acacttatga tcaaaaaaat tttcatactg ataagtgaaa
    14941 tgcgttctaa atatttcgtt cgatatagta aaaatataat aaaaacacat actgccaagg
    15001 taattataaa aatatcactt ttataatgaa taacttccgg aagatattga ttgctctcat
    15061 cccattcaaa aacactggta aacagaaaac ttacaaccgc aagaaagctg accagaatca
    15121 gtgaaaacca aactacaata tttcggaata cgctatcgat tatttttctc atgtgtgcct
    15181 cctatatact catacacgaa tagtaattga taatcatgcc tgaaacacca catactgccg
    15241 taatccccat aagaaggcag gttgcgtttt tatttttgaa atcccactct ctcagcataa
    15301 acacagtaca gaaaagaaaa gcaaaattca tgatccatcc ggttctgtat ccagacgccc
    15361 atactgtcgg cgaaaatccc ataacagcct ttgttgccag tcccataaca aatgttccga
    15421 tcagaatcca cgttgtccat gtattttttc caaacaaata aaacaaaatc agaatcaagc
    15481 aacacacgcc aataatactt cctactacaa tatatgtttt gtaattataa actctgtctc
    15541 caacaaaaat tcccatctcc tgtactaagc taaaaggtaa tctctcatca ccacgatatc
    15601 catgcatttt actaagtgat aacagaaaaa atgccggaat cgcacctaac acacgatact
    15661 gccatttttt atatttctgc cagattaaaa ccatcagtgt aaacagcatc ataaaaaaga
    15721 atacattatc ctgcaggaaa atctccttga tcaccgcact gatccctaaa tccactttat
    15781 tgaacagtga catatctgca aacactggaa accatgcttc aatttctttc tctttccgta
    15841 tgacatttcc agggctcagt ataatataga ttaaagacag cacactcaat ccggtctgta
    15901 tggctgcgta tttatagatt tttttagtac taaaccagca atagagatca aatatcacat
    15961 atgccatcaa tataacgact gacatctgtt ctgcgtttgc tccgatcagc agacaggcac
    16021 tgtaaaaaat catttcaaag ccattgattt tttcatgctc taaaaatttc ctcaacggat
    16081 acagccccat aattccaaaa ctgagcggcc acatatagtt tacagtcgtt gcaatccaac
    16141 ctgcagaatt caagatcgta tacgtaatag tcactacgag catactggtg attgtattaa
    16201 tataaatact gtcttctgtc ttttgaattg ccattttaga taaaaatatt gccacacagg
    16261 tgatcagagc ggaatccacg attctccaga aatataacgg cgctcttact gtaatcataa
    16321 gaagcaattc tatcgctgta cgggaggacc attccatata gcgctgatga agccatgtca
    16381 gaaatgaaaa tccctctgaa caggcaacct ctttaaacca gagatcatct ccaaaatcag
    16441 ggacaattcc tttatgtatc cataattcga ctaaaaacag aacgacaaac ggtacataga
    16501 ccgcactttt ctttttccac gccttttgca ttatttttct cctttttgtt tttcgcctat
    16561 gaattatatc acacttacta tttttactca atattccaga cttttcctgt ttttgcgaaa
    16621 aaatggggca ttgcatgaca tttcgcaaca ccccacactt tcttttttag atccttaaac
    16681 taaaatcagt tttatccaga gtcagattcg gactataata cggatcccct tcattcagaa
    16741 tttccttcca tctgtactgg aatgtccgga tttctccctg aaatcgaagt actttttctt
    16801 ctgtatcttc caatcctctg gattttgatt cataatgatg caattctgca tatggattat
    16861 aaacaactaa atatcctgct tctctgactt tcaggcaaaa atccacatca ttgaatgcta
    16921 ctgccagctt ttcctcaaat ccattgactt tctcaaatac ttttcgtttc gtcatcaaac
    16981 aggctgctgt aactgcactg taatcctgag ctgttacaat tcttccaaaa tatcccagag
    17041 aatcttttgg ttctccgaca aatgtatgtc cggcaactcc gccaagtcct atgatcacac
    17101 ctacatgctg aatggtatcg tcctcataat ataatcttgc tccgacaatt cccacatcat
    17161 cacgcatgca atatccaagc agttcttcaa tacagtctgg attgatgatt tctgtatcat
    17221 tatttaaaaa cagaagatat tcgcctttgg caaatcctac tccgtaatta ttaatcgcag
    17281 aatagttaaa ttcccgctcc cagaatacca cttttacttt tggattttct gcctgaagtt
    17341 tttcataata tgcaaaggtt tctttctttt cgctgttgtt ctcgattaca atatattcaa
    17401 tgtttttata agttcctttt tcttcaattg aacggataca cttatccaga tcttctgtgt
    17461 ggtctttgtt tggaatgatc acagatacca gaggctgctc ttttagacga tacttacttc
    17521 tgtaaattcc gtttaactgt tccgctgaaa cttcggcgtc aattccacat ctgtcataat
    17581 gcgcctgaat cgcacggatt cctgcttcaa aagcatatct cttgctttcc ggattctccg
    17641 ctgttgaatc cttatgcgca cgccagtgat acaaaatctt cggaatatgc cggatattca
    17701 ctgcctgctc tgcacaccgc aatacaaaat cataatcctg cgcaccgtca tactcatgat
    17761 ttaacagacc aactttttca aaaagacttc tctttaccac aaacaagtgg cagatgtaat
    17821 ttacacttct gagaaggtct atgttaaaat ctgtcttaaa atgcggctgg aaatgttctt
    17881 ttccatccat agaaatttta tcttcatctg tataaatcgc ctcaattgtc tgatcctgat
    17941 tcaacaaacg aacacactca taaaaagcat ccggagcaag caaatcatca tgatctccga
    18001 acgcaatata atcccctgtg cagattttca atgcttcatt tgtgttgtct gatatatgaa
    18061 gctggttttc attgtgaaca accttaattc ttgcatcttt agctgcatac tggcacaatt
    18121 tttctttgat cggagaatct tttccgcttc catctgacat acacaattcc cagtttccat
    18181 aagtctgctt cttaatagaa tctatcattt catccagata tttttctggt gttttataca
    18241 atggaactac gattgaaatt ttaggttcat acgtaaaatg ctgttttctt tgttccgcaa
    18301 gcattttctc agttgggaaa tgcgtcttca tccagttttt ataagaaact tcgtccttat
    18361 gtgtaagctt tgtgtaaaac cggtcaattg tccgttttat tccgaactgc tgatagtaca
    18421 catatgcttt gaatccactt tttttcaatt tctggattcc tttttttatt ttagacggtt
    18481 ttaaaatcaa ttctgatctg gcagtctgct ttcctgattt cattacaatt ttaatctttt
    18541 taggaactga gccactgcac tctgctgtaa aaccgtgtac ttctttctct gtacattctg
    18601 gatagtgacg cattacatca tttcttcttt tatactttat cacgttatcc aacttacggt
    18661 cttcactgtc atataacgta attttcactt cctctgtact tacaaaccag cctgttacac
    18721 ggaatacttg attccctacc gtaccaccat caatacagtg ttctatttta ttctccaact
    18781 tttccagatg tgaaattttt atcctcagac tttctctcat ctgattctga cactgattaa
    18841 ccaacgtcag atatttttta tttcgccagt cttttggcaa ttttacccag agatacattc
    18901 tattcttaat ttctgctttt ccatccgcac attgatgagc atctactaca tctgtatgct
    18961 gctctgtttt ataaaccagc ttttcatcat caatacttgc tacgagttga ttctccccca
    19021 tctcattctc cgcgaaccag ccctgtatca gcagagtatt tctatctttt acatgaaatc
    19081 tatatgctgt cacataaaat tcgtttttca tcctgttctc ctacttgaat aacttgtata
    19141 ataatttcat aaagatcaca ataaaagcaa caaaaccaag aagtaccaca aacgtctcca
    19201 catcaaatcg atggctgata tatctggccg caagcgctcc ctgcgtctca ttgtttttaa
    19261 tgctcagaac ttgtgctccc tcttcttttt gaggcactac ataaaagctt acgccatttg
    19321 cagcatctgc ccctgtctct gtaatctcaa acagatattc ttttcctttt gcagactcaa
    19381 ccgtttctat atcgaaccga ttgaatttat tatttttaat ttcgcttgct ttcgtacttc
    19441 ctgatgcgac tttcttattt gtcttagcat cccgaagaat atactgtact tctacatctt
    19501 ctacattccc agttacagag cacttaatat ttagcccatc cagaatatct tcttcactta
    19561 caaactcctg acttatcgtt tctccttcca gaagcactcc tgtactgata aatgctgacg
    19621 tatctgcatt tctgtcatat aaatatgagt ttttatcaat atgcgcatac agaaaagcca
    19681 aaactacaat aatcagaatt cctatgcctg tttttatata ttttttcatt tcaacaattc
    19741 ctctttacgc tttttcatat atgctgcata tttcctgagc atctccaaac atcttcaaca
    19801 ccccatgatc cagccatact accttattac aaattttttt cacctgttcg atactatgag
    19861 acacaaataa aattgttgtt ccctgatctt tcatattctg gattctggct tcacactttt
    19921 cctgaaatcg aaaatctcca acagacagca cttcatccac gatcagaata tccggaatcc
    19981 cgattgttgc gatcgcaaat gccaggcggg ataccattcc ggaagaaaaa ttcttgacgg
    20041 gaacatccat aaactcactt aattccgaaa actctacgat atcttcatac tgtgcttcca
    20101 tctgtgcacg attatagcca agcagggctc catttaaaaa cacattttct ctggctgtca
    20161 gatccatgtc aaatccggct cccagttcaa tcaatggtgc aatgtttcct ccgactgtca
    20221 cttgtccttt tgtcggcttt agcactcctg caatagtttt cagcatcgta ctttttccac
    20281 ttccatttag accaataagt cctaaagagt ctccttgctt aacctcaaaa gaaacatcct
    20341 ttagcgccca gaattcgtca taagaaacct gctttttcaa actctttatc acatattcct
    20401 taaaactgtc aaacttctcg gaagacaaac tgaatctcat cgagacatgt tcgacactga
    20461 taattgtttc atgttccata cacttctcct aaatattcag tataaactca tcctgatttt
    20521 tataaaatac atacgttccc aatataagcg caactgccac ttccacaact cccagtacaa
    20581 ctgctgaaaa tgttggtaaa gtattataaa acatcacatc ccggaacatc tgtaccatat
    20641 tcgtcagagg attgatattt acaactgtgc ggactgactc gggcagaatt gacattggat
    20701 aaataaccgg tgtcaaatac aatagacctg ttgtaaatac ggaatataaa tgcataatat
    20761 ccctaaattt aacagtcaaa gctgcgagca gcatccccac acccaatgaa aacaaaataa
    20821 tcatcgccaa cgggatcaca ctgaagatta ctgtccaatg caattctgca cgcattgcca
    20881 ccatgaccaa aatcaatgct accaaagatg ccatcagatt gataaaacta gagaacactc
    20941 tggcaatcac aaacaaatat ttaggtacat ataccttttt gatcagtgct gcgcttccta
    21001 tgatcgaagt catggaactt gtcgtcgcat cattaaaaaa gttaaaaatt aactgaccgc
    21061 tcaaaatgta cagcgggaaa ttttcaatat caaatttaaa aatactggaa aacaccactg
    21121 acagaataat catcataaac agcggattca acagtgtcca cagcacgccc aatacagacc
    21181 gccgatactt aatcttgata tctctcgcca caagttctgc taaaagcggc tgaaattttt
    21241 taaaattctg aatataactt gacacaatct tcctccggct tctatttatt caattctttg
    21301 attccgcccc atttctgatc tttttcagaa attgtcagct ccatatcttc cggaatcggc
    21361 cattcaatcc cgatatccgg gtcattccat gccagaccgc cctcatcatt tggatgatag
    21421 aaatctgtac atttataagc aaactctgct gagtctgaca gtacaacaaa tccgtgtgca
    21481 aaatccttcg gaataaagaa ctgcttttta ttctctgctg aaagcacaac tccataccac
    21541 tgtccatagg tcttagagcc ttttctcaaa tctacagcaa catcgaatac ttctccgctt
    21601 accacgcgaa caagcttgtc ctgcggataa ttgatctgga aatggaggcc acggagtact
    21661 ccctttttcg agctggattg attgtcctga acaaattcca tatcaattcc ggcttcttta
    21721 tagtcattgt aattataagt ctccataaag tatcctctct cgtccccaaa tacagctgga
    21781 gtaattactt ttaacccttc aatttcgcaa gtttctactt taatttttcc catgattaaa
    21841 attctcctct atttctgatc aatatatttt ccgtccagaa catctttcaa atatcgtcca
    21901 tactggtttt tctgataaag ttcacatgct tttccaagtt tttctttatc gatccagcca
    21961 ttattgtatg caatctcttc cagacatgca attttacgat tctgatgtgt ctcaactgtt
    22021 tttacgaaat ttgtcgcatc aaccagtgat tcatgtgttc ctgtatccag ccatgtaaat
    22081 ccctgcccaa gcagtgccac atccagattc cctttttcca gataaattct gttcagatcc
    22141 gtgatctcca gctctcctct ggcacttggt tcgatctgtt tggcatattc taccacatga
    22201 ttgtcataaa aatacaatcc agtcactgca taattagatt ttggatgctc tggtttttct
    22261 tccagtgaaa ctgcctttcc atcctgatcg aattcaacca caccaaaacg ctccggatcg
    22321 tccacataat atccgaatac tgtcgctcca tcttcttttg ccgcagcgac tttgagccgt
    22381 ttgctcagtc catgcccgtg gaaaatatta tctcccagga tcatcgcaca gctttccccg
    22441 ttaataaact cttccccgag taagaatgcc tgcgccaatc cgtccggtga tggctgcacc
    22501 ttataactga gctggattcc aaactggctt ccatctccta aaagttcttc aaatctcggt
    22561 gtgtcatccg gagttgaaat aatcaggatc tcacggattc ctgcttccat tagaatactg
    22621 agaggataat aaatcatcgg cttgtcataa attggaagta actgtttact tgttacctgt
    22681 gtcaacgggt aaagtcttgt tcctgatccc cctgctaaaa taataccttt catctttcaa
    22741 tcttcctcct gttcgtagat tcaacctcat aacgcaaacc agcagtatcc taggatactg
    22801 cctgtttgaa cgcattattt atacatttct tcgtaatatt tctgatagtc accgcttgta
    22861 acattcttca tccattcctc attctcaaag aaccatttga tcgtcaagcg aataccgtct
    22921 tcaaacattg tttccggata ccagcccact tcttctttga tcttatccgg cgcaatagca
    22981 taacgtctgt catgtccttt tctatcttcc acatatgtga tcagcttttc actgacaagt
    23041 tcttttcttg gatctccctc tggcaacatc tcctgtaatg tatccagaat aatgtggata
    23101 atctgaatat tctgtttttc attatgaccg ccaatattat acgtctcaaa aagtcttcct
    23161 ttttcctgaa ccatgtcaat tccttttgca tggtcttcta catacagcca gtctctgaca
    23221 ttctttccgt ctccgtatac cggaagattc ttgccctgca gagcattgtt aatgatcagc
    23281 ggaatcaact tctccggaaa ctgatacggg ccatagttat tgctacagtt tgtgatattt
    23341 gccggaaatt tatacgtatc catataagat tttaccagca tatccgatga tgctttactt
    23401 gcagagtatg ggctgtgcgg atcgtacgga gttgtctcat agaaatattc tccctcttct
    23461 tccagtgatc catacacctc atctgtagaa acatgaagga atttcttgcc ctccttaaat
    23521 gttccgtcag gaagctccca tgctgctttt gccgcattga gcatcacaag tgtcccgagt
    23581 acatttgtct ttacaaatac atccggattt ttaatgcttc gatcaacatg actctctgca
    23641 gcaaaatgta ctactctgtc aatctcgttc tcttcaaaaa tcttgttaat cgcatctgca
    23701 tcacagatat ctgcctttac aaatgtgtaa ttttctctgt cttctatatc tttcaggttc
    23761 tcaagatttc ctgcatatgt cagcttatct acattgatga tgcggatttc gttgtcatac
    23821 tttttaaaca tgtaatgaat atagtttgat ccaataaacc cggctccacc ggttactaaa
    23881 tatgttctca taattttaac ctccaatata ttctttagaa ttataacatt tctttaacat
    23941 ctatgcaaca attttaattg catcactccg aataactctt aatacgattt taaaataaaa
    24001 aagacccctt acattccatt catcgaaaca taaggggttc tttcctcaaa ttctgtttat
    24061 ttgtttttta atacatccat catatttaca atctggtatc cataattttt gctgcttgcc
    24121 catcctgttc cacttggatt ttctttaatt cccagccatt ccacataagg tgctgaattg
    24181 cgggtaacat atttaaatct tggatctaca catgcatttt ttaaagcttc agaagaagca
    24241 taggccttca gatgctggat ctgtgcccga attccggttc taacgtccgg aaaacttgct
    24301 gcctgcccct gtgaattgcc atccaatgct cccagtcccg caaaattgaa ttgttcaatc
    24361 tttactatac caccaaattt caaccatgca ctttctttca tggcctgcgc aaacgcaact
    24421 tcagctttta ctccttctgc tgtcgcctcg tcataatata tctggcaaaa atctctcaac
    24481 gtaggagctc caccttttcc aagtgcttcc gcaggatact gatttccagt actttcataa
    24541 taacgcatca tctgttccac tgtagtagta ctctccccca taatcggagt taaattttca
    24601 gtattctgtt ctgatgaatt accagaaacc tcatatgttg ttccagctac aaatgcatag
    24661 atacttgttt ctgttaagat atatacatgg atattatatg tacctttatt attctggtgt
    24721 ctggacagtt ccacttctgc tttatatgtt ccatcacctt gtttttcagc ggaataccag
    24781 acaatatcac tttgatcttc tttgctccaa accggaatct gcacttcctg cactccggat
    24841 ttagaagata cattctttac aacaacatca aaggttcctt ttgcagcatt atagtttttt
    24901 acttctattg ttcctttcgg ttttgaaact tcaaatgtgt ctgcaacaag aaacttctgt
    24961 actccatcaa tcattccata tacatgaaca ttatagctgc cagcagtttt atgattacta
    25021 atctcaattt ctgtactcca tgcatctgca tttttctgtg ttccctgata ccagatcaaa
    25081 tcatcctgtc cgtttgtatc actccacact gcaaactgca cactactgac tttcccaagc
    25141 gcatttgcat tttctatcgt ggcagtgtat ttcttttctt tcccatctgc attcgatata
    25201 cttactttgg gctccatttt gcttacatct ttgcttgtac cgtccacaaa ctgcatgata
    25261 ccgtttttgg cagttacata tgcatggata ttatatattg tattctgatt gtgattcttt
    25321 gtcttcacaa tcactttata gctgccatca ctctgtttat ctgcctgata ccacacaata
    25381 tcactctgat ttgactcgct ccaaactgga atatatactg cattgacgcc tgattttgaa
    25441 gttacatttt tcaagattac ttcaaaactt ccttttgact cgctgtaatt tttcacttcc
    25501 agagttcctg tcggagaact cactttaaaa gtagtatttc caattaacgt ctgctttttc
    25561 ccaactgtgc tgtatacatg gacattataa acacctgctg tcttatgatt tacaatcgaa
    25621 atttctgtac tccatgtaga tgatttcttc tttgcatcat accaaatcaa atcgtcctgt
    25681 ccatttacgt cactccacac cgcaaacctt acctgatctg cgtttctgac attctttgct
    25741 gtcaattcat actggctttc ttttccggtc tcatcttttg ctgtaatctc aactgcagaa
    25801 gcttctacct tctgcgtagt agaagcaacc atcgtctgac ttccgtcatt gcccagaata
    25861 tatatgtgaa tattatatgt accagtatta tttttgtggt ttgcaatgtc tactcctact
    25921 ttatatgttc catcagactg tttctctgct ctgtaccaaa caatatcact ctgaccccta
    25981 agactccaaa ccggaacctg tacttctttg acccctgccg gtgccactat attttcgaca
    26041 actacatcaa aagttccatt ttcagcacta taattcttaa ttgtaacatc tgcgcttggt
    26101 cccaccactt taaatgtaga atttccaata aatacctgtt tgccattcgt gagacttgca
    26161 taggcatgca cctgatagat atctcctatt tgatatcctg atatacttac atccgcttcc
    26221 catactccac ttgacgtttt ctgagctgta atccatctga tatcactttg atcaccttta
    26281 ctccaaaccg gaaactgtac accgcttact tcatctggca tatctgcaaa actcagtttc
    26341 acacggtata agtcttgtct tccatcaact gcagaaacct tcagttttgc agatgtatct
    26401 tttgaaacac gaaatgtcgt attacacaag attttcgtag atgatgaatt gtatacatgc
    26461 acattatatg tccctgctga ttttttgtgg tttttgatat caaaatttac tgtcccactg
    26521 tttccggata cagaatacca cttcaaatca tcctgtccat tgtcatcact ccatactgca
    26581 atttgtgctc cggcaccaac tccactcacc tcaatctgtg cagttccatt aaaatcattt
    26641 ttgttcttaa tctgcacagt tgcctgctcg tttccgttat tgcctttgct gaacccgtaa
    26701 gttgctgcaa ttcctgctgc atctgcttct cccagctttt tcaagaaatt ctcatctttc
    26761 aatttcgcgg catcagatgc actgtctaag aatgcgtgtt ctacgatcac ccctgtcatt
    26821 ccatactgtt tagaaagata gtttgtcgta aaatagtcat ctttatttcc attcggatct
    26881 gtctctccag tcgtaccgtc tttaatcttt gcaccacgat ttcttaatcc aagtgctgac
    26941 aactcgctca gaatcttatt tgccagattc tgaccttcct gatggattcc ttcattatag
    27001 cttttgtttg gatagtaaac ctcggctccc gttccccctc ctgtattgaa atgaatatct
    27061 acaaatacgg tcgctccgag tgccgctgca tctttgattc tctgattcag gcaatagctt
    27121 gtattctgtc ccggatattt acaggaaata gaatctctgt ccatatacac tgtaactccc
    27181 tgatactgct ccaatgcctg tttgcaatac tgtgcaactt taaaagtaag ctcttcttct
    27241 tttagtccat tgccgctggc tcctgtatgt gtcgcatcat gtccggcaca gatcaccacc
    27301 gttttattgg ctcttgcttc tcttgcaagc ggtgatacag gatctgcctc ttccagcact
    27361 cctgccacag tttcctcaat gttctctgta tctgaagaag cctcgatcac atttccgtct
    27421 tcactaagtg aatatactgc cacatccggc actgcttcct ctgaagaatt ctcctcttcc
    27481 ggttgtactg taactgtata acccgcatca atttcttcat ccagcagatt taccgtagaa
    27541 cttactcccg agctctgata tgtcaggcta tccagctgat acacatcttc tgctgatcct
    27601 tccggataat cctgtgtaaa caaaactgta ttgttcacaa ttgctgacgc cggcatttca
    27661 aactgttcac ctgtaacaac agaactataa tgtagaactg cagattccag caccaggctc
    27721 tcatccgaaa atccaactgc tatattctgt gtctgtggca tattgaccac tgcttcatcc
    27781 acatatacat actccagaat tccttccaaa ggctgctgtg ttgtctcctg ctgtgtgtct
    27841 gtttcatcta aagtctgctg ttgctcctgt gattgtatat ctgcttctcc tgcaacagaa
    27901 tccatctccc cagctgccgc cacattcatt ccagctgtag taaacaccat cataaacacc
    27961 agtaacagcg taagtacttt ctgtactttt ttcattcttt tgttttaacc cctttctctc
    28021 ttgcgtaata tctatatata aaagcctatg gctgaatatt tgtctctttg caaataaaaa
    28081 ttggtctttt tttcaattcc atatatgctt ttgcaaaata ctcccctaaa ataccgatac
    28141 aaaacagttg aattccacct atgaatagca taatacatac catagacggc catccagagg
    28201 tcggatctcc aaaaatcagt gtttttgcaa caattacgat aatcaatata aacgcaagta
    28261 cacagagtac aattcccatg attgctgaaa tcagcaacgg tactgtagaa aaagcaacaa
    28321 tcccttcgat tgcatacaca aacaatttcc agaaagacca ctttgtctca cctgcaactc
    28381 tctcgatgtt ttcatattcc atccattttg ttttatatcc aacccaacca tacagacctt
    28441 ttgaaaatct attgtattct tccagctcca gaagactgtt tacaaactga cgcgtcatca
    28501 atcgataatc tctggctcca tctacaattt ccgtatctga aattttcttg atcaaatgat
    28561 aaaatctcct tgcaaaaaat gaccggatct ttggctctcc ttttcttgtc actcgtcttg
    28621 ttgccaccga atcatatcct tcttctttga tataatgcat catctccggc aataacctcg
    28681 gtggatcctg cagatcagca tccataatcg tgacatagtc cccagaagca taacttaatc
    28741 ctgcatacat tgctgcttct ttcccaaaat ttctggaaaa tgatacatac tttatacatt
    28801 cgtctttttt tgccagttct tttgcaactt caagagttct gtcctttgac ccatcatcta
    28861 caaaaagaac ttcaaactgg aattctttca taatctccat tacttttttt atttcattat
    28921 aaaacaaagg aatactttct tcttcgttat agcatgaaac aactacactt attttttcca
    28981 tcgcttttcc tcttcatatt ttcttaactt cactatagca catttattaa gatgcttcaa
    29041 tttttcattt ttacttcata tccatgactg aatcatcaat attttctttt cctgctatct
    29101 gttcataaaa aatagaacgt tttctaattt ccttattcag ggtatccatt cccacttttt
    29161 ctgcaagagc cggctctgct gaaaacaaat ttgttccgag tcccaggcga tccccttcaa
    29221 tctgtgctcc caatgccgca attgtcgttg gaaacatatc cattgttgtc gccattctgt
    29281 ttttctgatt gaccggaaca attggagcat tgatgatcgt attatataca cctcgcgtat
    29341 aatcttccgg cacatcctga caaaaatcac tgtccatcgt caaatgatct cctacaatca
    29401 caatcgtggt attctcataa aatggctgtg ctttcaacca gttcacaaaa tccacgacct
    29461 gtctgctagc gcaggacatc acgtttgcat actgattgcc cggatgttca tcctggcaca
    29521 gatcacaaac atatccatct tcaaaatggg tgtcaacagt cagcatcgta aagttaaatg
    29581 gttgtccgct gttagccaga tttgttactt cccgccttgc aaaatcgtac aatttatgat
    29641 cctcatatcc ccaccacact cgataatccg gaggtatgag accgttttgc tgagcgtaga
    29701 gcaaatcttt cacttcataa tttccatgtc cctcaaaata ctgttttctt ccggcaaact
    29761 ccccttctga gccaaacata acaacctgtt tgtagccttg taccgctaac atatcaccca
    29821 gaacagttgc tcccggaagc acttgcacat cttcctgtat attctccgcg cgtagcttta
    29881 ccttcagcgg caacccggat gtctgcgcca ccatagctcc cattgtccac gtggcaccat
    29941 cagaaggaat cagaccgccc agcatatcgc ccgtcgaaaa attaacgttt tccattgcca
    30001 gctgcgtcat ctccggaata tcattttctg caaaagcgcc gcctacatct gttgaagcgt
    30061 acgtggattc catggactcc ataaaaatgt acaccagatt tctcttctgc tcgggaaatg
    30121 taaccggaac caacgccgga tccatataat tctcctgcaa aaacatcgag atcgtatcct
    30181 gattttccag atattctcca acatccagtt cattccacac catctgtccg gatgatacaa
    30241 tcagtgccat cgaacctgca accgctccaa tctgtaccac ccattttgta atctttgttt
    30301 ttcgcaccat tacgattacc aataccacaa aaaacactgc catcactgcg gccggtatac
    30361 aagtctctac aaaatcccag agtacctcat gactggtgcc ctggattggt gtctttaact
    30421 gagcgacaag ctcctccata gacagatttg tccatgtcgc cagcatccag tttgccgctt
    30481 catgaagcaa gattgccaga aatgagaata acactgctaa catacacaac agcactttca
    30541 tcacaatctg aatcaccttt atcatgtttc ccaaacgaac aatcccgata ttcactttca
    30601 actgttcttc cgttatatcc gtcagattct tctgctcttt ttgcgcccct ctgtctaact
    30661 cttttttcgg cttctttcta tgctttttct ttaactcctg caatcttatg tcctctcctt
    30721 aattccaact tttatactga ccacttttac gcggcaaaag ggaacgcagc ctgatttgct
    30781 gcgccccctc tcttattttt tatttcagaa taactttttc ggataaactc ccgcatgaat
    30841 caaagcctgc aattccgaaa caacggaatc cttatcttct ttataagtca caccaaacca
    30901 tttatctttt gatgtcagca cttttactgc aagctttttc tccgccaaaa gatcaccaat
    30961 gatcgtcggc agtaaatatt ctgctttcaa gttatctgcc ggggtatttg ctacaaatgc
    31021 ctcaaatcca ctttccagaa tctggaagaa ctctggcgta agtccccaca tattcatgga
    31081 aacgctggat tcaatatcga ttggaatgta cgcttctccc ttgtgaacgg ctgctccgct
    31141 ctcatatttc tcaatattgg acgtctccac aatatctgca agatatccgt tttcatttac
    31201 tttacagact ccgcgtgtta ccccgccgtt atcactcagt gtatttttca aaacaaagct
    31261 gaccatacag atctcatcct ttgatgttgt ctctcttgta aggtactcgt acgcttccac
    31321 atatgcctgc tttccatagt aatcatctgc attaatgacc agaaacggac tgtctacaac
    31381 atccttacag cagagaattg cctgtccggt tccccatggc tttgtgcgac ctgaaaaacg
    31441 ttcccgatac gcctgcggaa tatcatctac ctcctgatat gcgtaagcaa cctctacaac
    31501 cttttcaatc cggtttccga tcacttcttt aaaatctttt ttcagatcct ttctgattac
    31561 aaatacaacc ttatcaaatc cggcttccat tgcatcataa atggagtaat ccataataat
    31621 ctctccgttt ggtcccaccg gttccagctg tttgattccg ccaccaaatc tgcttccaat
    31681 ccctgccgcc attacgacta atgttgcttt gttcatgttt ttctcctttg ctctgtaacc
    31741 tttattctcc cagtccat
//
