LOCUS       BGC0002305              7452 bp    DNA     linear   BCT 21-JUN-2020
DEFINITION  Streptomyces sp. strain MA37 legonoxamine gene cluster, partial
            sequence.
ACCESSION   BGC0002305
VERSION     BGC0002305
KEYWORDS    .
SOURCE      Streptomyces sp
  ORGANISM  Streptomyces sp.
            Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
            Streptomyces.
COMMENT     ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2022-11-08 08:09:17
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 7452
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     gene            1..1038
                     /gene="lgoE"
     CDS             1..1038
                     /codon_start=1
                     /gene="lgoE"
                     /gene_functions="transport (smcogs) SMCOG1033:iron compound
                     ABC transporter, periplasmic (Score: 84.5; E-value:
                     9.9e-26)"
                     /gene_kind="transport"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="QKS42875.1"
                     /transl_table=11
                     /translation="MPHNSPTRLSRRGLLTAGGVAAFGALLTACGGSGGSGSSAKEGDG
                     GGSWSFTDDRKKKVSAKSTPKRIVAFTGTAAALVDFGLDQQIVGVFGETKDKDGKAVPQ
                     AGDLNVDKVTVLGNAWGEFSIEKYAALRPELLVTHMFNEGALWYVPDESKDKILGLGAP
                     SVAIRTARVPMTEPIKRYAELAESLGADLKAKKVTDAKARFEAAAETLRKAAKASGGLK
                     VMAASASPDLMYVSNPKSNSDLMYFAELGVDLIVPEKLDEGGYFESLSWENAGKYKADL
                     ILLDNRDGQLQPKALADKPAWAELPAVKANQITPWDSVPRFSYAGAAPLLENLAKAIQD
                     AKKVS"
     source          1..7452
                     /db_xref="taxon:1931"
                     /isolation_source="soil"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces sp."
                     /strain="MA37"
     misc_feature    <1..>7452
                     /note="legonoxamine gene cluster"
     subregion       1..7452
                     /aStool="mibig"
                     /contig_edge="True"
                     /label="Other"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..7452
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            1046..1891
                     /gene="lgoF"
     CDS             1046..1891
                     /codon_start=1
                     /gene="lgoF"
                     /gene_functions="other (smcogs) SMCOG1200:vibriobactin
                     utilization protein ViuB (Score: 279.5; E-value: 3.8e-85)"
                     /gene_kind="other"
                     /product="siderophore interacting protein"
                     /protein_id="QKS42876.1"
                     /transl_table=11
                     /translation="MTTATVAGQFRFFDAHVVRSRRLGPSMVRITFGGEQLREFAGGGR
                     DQSFSLFLPQPGQHSPVLPETHGEGRLAEWRAMDPAVRAVMRSYTVREQRREQAEVDVD
                     FALHGDLGPASRWAGEASGGDRVVLLGPAVEDNRSVGFRPPLGTDWVLIAADETALPAV
                     GAILDWLPAGMRARVWIEVPHAEDVMDLPCAGDAEITWLVRDHAPGPRPALLVDAVRDA
                     GLPGGMPYAWIAGESGAVKALRRHLVGERGFDRKKVQFSGYWRLGASEEDLRAEALAAA
                     "
     gene            2190..3707
                     /gene="lgoA"
     CDS             2190..3707
                     /codon_start=1
                     /gene="lgoA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1180:Decarboxylase, pyridoxal-dependent (Score: 389.5;
                     E-value: 3.1e-118)"
                     /gene_kind="biosynthetic-additional"
                     /product="PLP dependent decarboxylase"
                     /protein_id="QKS42877.1"
                     /transl_table=11
                     /translation="MSYQGRSHLFNDRNVDHYRRSLTDGVERVATRIARTERPFSGVTP
                     DQLGPEIAGIDLERPLSDPAAALDELESVYLRDAVYFHHPRYLAHLNCPVVIPALLGEA
                     VLTAVNSSLDTWDQSAGGTLIERRLIDWTAGRIGLGEDADGVFTSGGSQSNFQALLLAR
                     EEAFARAAAAAAYAGTTLSKHDFLPRLRILASEAGHFSVQKSAKMLGLGTDAVIAVETD
                     QDRRMRPAALARELERCRTEDLVVMAVVATAGTTDFGSIDPLPRIADLCSWAGAWFHVD
                     AAYGCGLLASPTRRHLLDGIERADSVTVDFHKSFFQPVSSSAVLVRDGSVLRHATYYAD
                     YLNPARMAEQRIPNQVDKSIQTTRRFDALKLWLTLRIMGADAIGSLFDEVVDRAAQAYD
                     LLAGDPRFEVVTKSQLSTVVFRYLPPAGPERELADDANLHAREAIAASGDAVVAGTKVD
                     GRHYLKFTLLNPETTLDDIAHVLELLAEHAGRFVDEKSDPELRRKAG"
     gene            3801..5099
                     /gene="lgoB"
     CDS             3801..5099
                     /codon_start=1
                     /gene="lgoB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1080:lysine/ornithine N-monooxygenase (Score: 427.9;
                     E-value: 6.3e-130)"
                     /gene_kind="biosynthetic-additional"
                     /product="FAD dependent amine monooxygenase"
                     /protein_id="QKS42878.1"
                     /transl_table=11
                     /translation="MSTHDFIAIGLGPYNLGLACLTEPLDELDGLFLESKPEFDWHPGM
                     LLDFATLQTPFMADLVTLADPTSPYSFLNYLKESGRLYSFYIREIFYPVRSEYNDYCRW
                     AAAKLDTVRFGHEVTSVEYDESEGLYTVHSTVAGTGETVRHQARHLVLGTGTPPFVPEA
                     CEGLGGDLIHNSGYLDAKANLQTKDSITVVGSGQSAAEIYYDLLADTDAHGYKLNWVTR
                     SPRFFPLEYTKLTLEMTSPEYVDYFHALPEDTRYRLEAEQKGLFKGIDADLINNIYDLL
                     YQKSLRGPVPTRLLTNTALNTASYDAESGTYTLGLHHAEQERDFTLATQGLVLATGYRY
                     RVPAFLEPVHDRIRWDRHGRFDVARNYSIDTTGRGIFLQNAATHAHSVTSPDLGMGPYR
                     NSWILRELLGRDVYPVEKSIAFQEFGAPQGDLA"
     gene            5096..5674
                     /gene="lgoC"
     CDS             5096..5674
                     /codon_start=1
                     /gene="lgoC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1203:putative siderophore biosynthesis protein (Score:
                     135.7; E-value: 4.7e-41)"
                     /gene_kind="biosynthetic-additional"
                     /product="acyl transferase"
                     /protein_id="QKS42879.1"
                     /transl_table=11
                     /translation="MTALTGFSRTDDRIGTFTLRPLDPEADAALLHPWVTHPKAAYWMM
                     QDADVATVAHEYRKIVDNPHHDAFVGLVDGTPCFLVERYDPARAELVGMYEPQEGDVGM
                     HFLCAPTDTPVHGFTRAVITTVMAWLFADPAHRRVVVEPDVRNTAVHGLNLAVGFEPAA
                     TIAKPEKDALLSFCTREQFEAAVTRGAAQ"
     gene            5671..7452
                     /gene="lgoD"
     CDS             5671..7452
                     /codon_start=1
                     /gene="lgoD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /product="LucA/LucC family siderophore biosynthesis
                     protein"
                     /protein_id="QKS42880.1"
                     /sec_met_domain="IucA_IucC (E-value: 2.5e-82, bitscore:
                     264.8, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNPHDAIAHLTPAHWDRANRQLVRKALAEFAHERLFAPERLDDGR
                     YALRSDDGGVEYRFTARLLTLDHWQIDADSITRHRGDDELPLDAVDFCIEMRGTLGLSD
                     QILPVYLEEISSTLSGSAYKAAKPQITAAELAKADFQTVETNMTEGHPCFVANNGRLGF
                     GVHEFHAYAPEAASPVRLVWLAAHRDHTTFTSAADIDYGRLMREELGEETLARFTRTLT
                     GLGLDPDAYLLLPVHPWQWWNKLSVTFASEVATQRLVLLGPGDDEYLAQQSIRTFFNTS
                     APQKHYVKTALSVLNMGFMRGLSAAYMEATPAINDWLAELIASDEVFARTGLTIIRERA
                     AIGYRHRQYEAATDRYSPYRKMLAALWRESPVRDLEPGRRPATMASLLHTDAEGRSFAA
                     ALIEQSGLAPEVWLRRYLDAYLVPLLHSFYAYDLAFMPHGENVIMVLDDSGTVERVIFK
                     DIAEEIVVMDPEAELPEQVQRVRAAIPEEERLLSIFTDVFDCFFRFLSAALEEAEVLGE
                     EAFWRTVAECVTAYRESVPQLAEKFERFDIFTEEFALSCLNRLQLRNNQQMVDLSDPSA
                     ALQFVGTLRNPIAPFAP"
ORIGIN
        1 atgccgcaca acagccccac ccgcctctcc cgccgcggcc tgctcaccgc gggcggcgtc
       61 gccgccttcg gtgccctcct caccgcctgt ggaggaagcg gcggttcggg ctcctccgcc
      121 aaggagggcg acggcggcgg cagctggtcc ttcaccgacg accgcaagaa gaaggtctcc
      181 gccaagtcga cgccgaagcg catcgtcgcc ttcaccggca ccgcggccgc cctcgtcgac
      241 ttcggtctcg accagcagat cgtcggcgtc ttcggcgaga ccaaggacaa ggacggcaag
      301 gccgtcccgc aggccgggga cctgaacgtc gacaaggtga ccgtgctcgg caacgcctgg
      361 ggcgagttca gcatcgagaa gtacgcggcc ctgcgccccg aactcctcgt gacgcacatg
      421 ttcaacgagg gtgcgctctg gtacgtgccg gacgagagca aggacaagat cctgggcctc
      481 ggcgccccca gcgtcgcgat ccgcaccgcc cgcgtcccca tgaccgagcc catcaagcgc
      541 tacgccgagc tggccgagtc cctcggcgcc gacctgaagg ccaagaaggt caccgacgcc
      601 aaggcccgct tcgaggccgc cgccgagacc ctgcgcaagg ccgccaaggc gagcggcggg
      661 ctcaaggtca tggccgcgtc cgccagtccc gacctgatgt acgtctccaa ccccaagtcc
      721 aactcggacc tcatgtactt cgccgagctc ggcgtcgacc tgatcgtccc cgagaagctg
      781 gacgagggcg gctacttcga gagcctcagc tgggagaacg ccggcaagta caaggccgac
      841 ctgatcctgc tggacaaccg cgacggccag ctgcagccca aggccctcgc cgacaagccc
      901 gcctgggcgg agctccccgc cgtcaaggcg aaccagatca ccccgtggga ctccgtgccc
      961 cgcttctcct acgcgggcgc cgccccgctg ctcgaaaacc tcgccaaggc catccaggat
     1021 gccaagaaag tgagctgacg ttcccatgac gaccgccacc gtcgccggac agttccgctt
     1081 cttcgacgcc catgtcgtcc gcagccggcg cctcggcccc tccatggtca ggatcacctt
     1141 cggcggagaa cagctgaggg aattcgccgg aggcggccgc gaccagagct tctcgctgtt
     1201 cctgccgcag ccggggcagc actccccggt gctgcccgag acccacggcg agggccggct
     1261 cgcggaatgg cgggccatgg acccggcggt gcgggccgtc atgcgctcgt acaccgtgcg
     1321 cgagcagcgc cgcgaacagg ccgaggtcga cgtcgacttc gccctccacg gcgacctcgg
     1381 cccggcgtca cgctgggccg gggaggcctc cggcggcgac cgggtcgtgc tgctcggccc
     1441 ggccgtcgag gacaacagga gcgtcggctt ccgtccgccg ctgggcaccg actgggtgct
     1501 catcgcggcc gacgagaccg cgctccccgc cgtcggcgcc atcctcgact ggctgcccgc
     1561 cggcatgcgc gcccgggtct ggatcgaggt cccgcacgcc gaggacgtca tggacctgcc
     1621 ctgtgcgggc gacgccgaga tcacctggct cgtccgcgac catgcccccg gaccgcgtcc
     1681 cgccctcctc gtggacgcgg tccgggatgc cgggttgcct ggcggcatgc cgtacgcgtg
     1741 gattgcgggg gagtcggggg ccgtgaaggc gttgcggcgt cacctcgtcg gtgagcgcgg
     1801 tttcgaccgc aagaaggtgc agttctccgg gtattggcgg ctgggggcct ccgaggagga
     1861 cctgcgcgcc gaggccctcg cggcggcgta ggacgttcgg gcgcgccccg taggggcgcc
     1921 ccctgtgagg cttgcgcccc gtcaggggcn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1981 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnttcgac
     2041 tgcgggcgcn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnngccc ctacggggcg
     2101 caggccttac ggggggttac cccatcggga tcaacttagg ttaggcttgc ctaagttcag
     2161 ccagcccgac gaaccgttga ggactgacca tgagttacca ggggcgttcg cacctgttca
     2221 acgaccgcaa cgtcgaccac taccgacgct ccctgaccga cggagtcgaa cgcgtcgcca
     2281 cccggatcgc ccgcaccgag cgcccgttct ccggcgtcac gccggaccaa ctgggccccg
     2341 agatagccgg gatcgacctg gagcggccgc tgagcgaccc cgccgcggcc ctcgacgagc
     2401 tggagagcgt ctacctgcgc gacgcggtct acttccacca cccccggtac ctggcgcacc
     2461 tcaactgccc ggtcgtcatc cccgccctgc tcggcgaggc cgtcctcacg gccgtcaact
     2521 cctcgctgga cacctgggac cagagcgcgg gcggcaccct catcgagcgc cgactgatcg
     2581 actggacggc cgggcgcatc ggcctcggcg aggacgccga cggcgtgttc accagcggcg
     2641 gcagccagtc caacttccag gccctgctgc tcgcccgcga agaggccttc gcccgggccg
     2701 ccgccgcggc cgcgtacgcc gggaccacgc tctccaaaca cgacttcctc ccccggctgc
     2761 gcatcctcgc ctccgaggcg ggccacttca gcgtccagaa gtccgcgaag atgctcggcc
     2821 tcggcacgga cgccgtcatc gccgtcgaga ccgaccagga ccggcggatg cggcccgcgg
     2881 cgctcgcccg cgagctcgag cgctgccgca ccgaggacct cgtggtcatg gccgtcgtcg
     2941 ccacggccgg caccaccgac ttcggctcca tcgacccgct gccccgcatc gccgacctgt
     3001 gctcctgggc cggcgcctgg ttccacgtgg acgccgcgta cggctgcggc ctgctggcct
     3061 cccccacccg gcgccacctg ctcgacggca tcgagcgcgc cgactcggtc accgtggact
     3121 tccacaagtc cttcttccag ccggtcagtt cgagcgccgt cctggtccgc gacggctccg
     3181 tgctgcggca cgcgacctac tacgcggact acctcaaccc ggcccgcatg gccgagcagc
     3241 gcatccccaa ccaggtcgac aagagcatcc agaccacgcg ccgcttcgac gccctcaaac
     3301 tctggctgac cctgcgcatc atgggcgccg acgcgatcgg ctcgctcttc gacgaggtcg
     3361 tggaccgcgc cgcccaggcc tacgacctgc tggccggcga cccccgcttc gaggtcgtca
     3421 ccaagtcgca gctgagcacc gtcgtcttcc gctacctgcc cccggccggc cccgagcgcg
     3481 aactggccga cgacgccaac ctccacgccc gcgaggccat cgccgcctcc ggcgacgccg
     3541 tcgtggccgg caccaaggtc gacggccgcc actacctgaa gttcaccctg ctcaaccccg
     3601 agacgacgct ggacgacatc gcgcacgtcc tggaactgct cgccgagcac gcgggacggt
     3661 tcgtcgacga gaagtccgac cccgagctgc gccgcaaggc cggctgaccc cctcggctca
     3721 cccccctcga ctccccctcg nnncccccct cgactccccc tcgccccgcc cctgcacgcc
     3781 cccgcaccga gagaccacgc atgtccaccc atgacttcat cgcgatcgga ctgggcccct
     3841 acaacctggg tctggcctgt ctgaccgaac ccctcgacga actcgacggg ctcttcctgg
     3901 agagcaagcc ggagttcgac tggcacccgg ggatgctgct ggacttcgcc acgctgcaga
     3961 cgcccttcat ggccgacctc gtcacgctgg ccgaccccac ctccccgtac tccttcctca
     4021 actacctgaa ggaatcgggc cggctgtact ccttctacat ccgcgagatc ttctacccgg
     4081 tccgcagcga gtacaacgac tactgccgct gggccgccgc gaagctcgac accgtccgct
     4141 tcggccacga ggtcacctcc gtcgagtacg acgagtccga gggcctctac accgtccact
     4201 cgaccgtggc cggcaccgga gaaacggttc gccaccaggc ccggcacctg gtcctgggca
     4261 ccggcacccc gccgttcgtc cccgaggcct gcgagggcct gggcggcgac ctgatccaca
     4321 actccggcta cctggacgcc aaggcgaacc tgcagacgaa ggacagcatc accgtcgtcg
     4381 gcagcggcca gagcgccgcc gagatctact acgacctgct ggcggacacc gacgcccacg
     4441 gatacaagct caactgggtc acccgctccc cgcggttctt ccccctcgaa tacaccaagc
     4501 tcaccctgga gatgacctcc cccgagtacg tggactactt ccacgccctc ccggaggaca
     4561 cccgctaccg cctggaggcc gagcagaagg gcctgttcaa gggcatcgac gcggacctca
     4621 tcaacaacat ctacgacctg ctctaccaga agagcctgcg cggcccggtc cccacccggc
     4681 tgctcaccaa caccgccctg aacaccgcct cgtacgacgc ggagagcggc acctacacgc
     4741 tcggcctcca ccacgccgag caggagcggg acttcaccct cgccacccag ggcctggtcc
     4801 tggccaccgg ctaccgctac cgcgtccccg ccttcctgga gccggtccac gaccgcatcc
     4861 gctgggaccg ccacggccgc ttcgacgtcg cccgcaacta cagcatcgac accaccggcc
     4921 gcggcatctt cctgcagaac gccgccaccc acgcccacag cgtcacctcc cccgacctgg
     4981 gcatgggccc ctaccgcaac tcctggatcc tccgcgagct gctcggccgc gacgtctacc
     5041 cggtcgagaa gtccatcgcc ttccaggagt tcggcgcacc gcagggggac ctggcatgac
     5101 cgcgctcacc ggcttctccc gcaccgacga ccgcatcggc accttcaccc tgcgccccct
     5161 cgaccccgag gccgacgccg ccctgctgca cccctgggtg acgcacccca aggccgcgta
     5221 ctggatgatg caggacgcgg acgtggccac ggtcgcccac gagtaccgca agatcgtcga
     5281 caacccccac cacgacgcct tcgtcggcct cgtcgacggc accccctgct tccttgtcga
     5341 gcgctacgac cccgcccgcg ccgagctcgt cggcatgtac gagccgcagg agggcgacgt
     5401 cggcatgcac ttcctgtgcg cgccgaccga caccccggtg cacggcttca cccgcgccgt
     5461 gatcaccacg gtgatggcgt ggctcttcgc cgaccccgcc caccggcgcg tggtcgtcga
     5521 gcccgacgtc cgcaacacgg ccgtgcacgg gctcaacctg gccgtcggct tcgagcccgc
     5581 cgccaccatc gccaagcccg agaaggacgc actgctgagc ttctgcaccc gggagcagtt
     5641 cgaggccgca gtgacccgag gagccgcgca gtgaacccgc acgacgccat cgcccatctg
     5701 acccccgccc actgggaccg cgccaaccgc caactggtcc gcaaggcgct cgccgagttc
     5761 gcccacgagc ggctgttcgc cccggagcgg ctcgacgacg gccggtacgc gctgcgcagc
     5821 gacgacggcg gcgtggagta ccgcttcacc gcccgcctgc tgacgctcga ccactggcag
     5881 atcgacgccg acagcatcac ccgccaccgc ggggacgacg aactgccgct cgacgccgtc
     5941 gacttctgca tcgagatgcg cggcacgctc ggcctgagcg accagatcct cccggtctac
     6001 ctggaggaga tcagctcgac cctgtcgggc tcggcctaca aggccgccaa gccgcagatc
     6061 acggcggcgg agctggccaa ggccgacttc cagacggtcg agacgaacat gaccgagggc
     6121 cacccgtgct tcgtcgccaa caacgggcgg ctgggcttcg gcgtgcacga gttccacgcg
     6181 tacgcccccg aggccgcgag cccggtccgg ctcgtctggc tggccgccca ccgcgaccac
     6241 accacgttca cctcggccgc ggacatcgac tacggccggc tgatgcgcga ggaactcggc
     6301 gaggagaccc tcgcccgctt cacgcggacc ctcaccgggc tcggcctcga ccccgacgcc
     6361 tacctgctgc tgcccgtcca cccctggcag tggtggaaca agctgtcggt gaccttcgcc
     6421 tccgaggtcg ccacgcagcg cctcgtcctg ctcggcccgg gcgacgacga gtacctcgcc
     6481 cagcagtcga tccgtacctt cttcaacacc agcgcgccgc agaagcacta cgtgaagacg
     6541 gcgctctccg tcctcaacat gggcttcatg cggggcctgt ccgccgccta catggaggcg
     6601 accccggcca tcaacgactg gctggcggaa ctgatcgcgt ccgacgaggt gttcgcccgg
     6661 accggcctga cgatcatccg tgagcgcgcc gcgatcggct accgccaccg ccagtacgag
     6721 gccgccaccg accggtactc cccgtaccgc aagatgctcg ccgccctgtg gcgcgagagc
     6781 cccgtccgcg acctggagcc cggccggcgc ccggccacca tggcctcgct gctgcacacc
     6841 gacgcagagg gccgctcctt cgcggccgcg ctgatcgaac agtcgggcct ggcccccgag
     6901 gtgtggctgc gccgctacct ggacgcctac ctggtcccgc tgctgcacag cttctacgcc
     6961 tacgacctgg ccttcatgcc gcacggcgag aacgtcatca tggtgctcga cgacagcggc
     7021 acggtcgagc gggtgatctt caaggacatc gccgaggaga tcgtcgtcat ggacccggag
     7081 gcggagctgc ccgagcaggt ccagcgggtc cgggccgcca tccccgagga ggagcggctc
     7141 ctctcgatct tcaccgacgt cttcgactgc ttcttccgct tcctgagcgc ggccctggag
     7201 gaggcggagg tcctcggcga ggaggccttc tggcggacgg tcgccgagtg cgtcaccgcc
     7261 taccgggagt ccgtgccgca gctcgcggag aagttcgagc ggttcgacat cttcaccgag
     7321 gaattcgcgc tgtcctgcct caaccggctc cagctgcgca acaaccagca gatggtcgac
     7381 ctctcggacc cgtcggcggc actccagttc gtcggcaccc tccgcaaccc gatcgccccc
     7441 ttcgccccgt ga
//
