BGC0002313: streptozotocin biosynthetic gene cluster from Streptomyces achromogenes subsp. streptozoticus
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Location: 1 - 9,914 nt. (total: 9,914 nt).
This entry is originally from NCBI GenBank MK303572.1.

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core biosynthetic genes
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transport-related genes
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002313
Short description streptozotocin biosynthetic gene cluster from Streptomyces achromogenes subsp. streptozoticus
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • other (other)
Loci
MK303572.1
1 - 9914
via Enzymatic assays, Knock-out studies
Compounds
  • streptozotocin
Species Streptomyces achromogenes subsp. streptozoticus [taxonomy]
References
Chemical products information
streptozotocin Evidence:
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Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • QBA82197.1
  • sznA
 162 - 755 (+) RNA polymerase sigma-70 factor
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    • QBA82198.1
    • sznB
    		 752 - 1552 (+) O6-methylguanine-DNA--protein-cysteine methyltransferase
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      • QBA82199.1
      • sznC
      		 1611 - 2156 (+) methylated-DNA-[protein]-cysteine S methyltransferase
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        • QBA82200.1
        • sznD
        		 2239 - 3006 (+) Fe(II)-2-oxoglutarate-dependent oxygenase family protein
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          • QBA82201.1
          • sznE
          		 3290 - 4375 (+) methyltransferase domain-containing protein
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            • QBA82202.1
            • sznF
            		 4446 - 5861 (+) iron-containing redox enzyme
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              • QBA82203.1
              • sznG
              		 5852 - 6226 (+) rieske domain-containing protein
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                • QBA82204.1
                • sznH
                		 6372 - 7622 (+) ATP-grasp domain-containing protein
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                  • QBA82205.1
                  • sznI
                  		 7619 - 8914 (+) MFS transporter
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                    • QBA82206.1
                    • sznJ
                    		 8958 - 9914 (+) alpha/beta hydrolase
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                      Biosynthesis information
                      Annotation changelog

                      Entry version: 2

                      Date
                      Changes
                      Submitters
                      Reviewers
                      2022-10-07
                      Changed chemical structures for compounds: streptozotocin.
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      2022-10-07
                      Added NPAtlas links to compounds: streptozotocin.
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                      Entry version: 1

                      Date
                      Changes
                      Submitters
                      Reviewers
                      2022-09-15
                      Entry added
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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