LOCUS       BGC0002317             12328 bp    DNA     linear   BCT 15-SEP-2015
DEFINITION  Pantoea agglomerans strain P10c PAP10c_contig_8, whole genome
            shotgun sequence.
ACCESSION   BGC0002317
VERSION     BGC0002317
KEYWORDS    .
SOURCE      Pantoea agglomerans
  ORGANISM  Pantoea agglomerans
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Erwiniaceae; Pantoea; Pantoea agglomerans group.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 17:19:11
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12328
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:11122]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11122
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..12328
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..12328
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0002317"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..12328
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(146..418)
                     /locus_tag="PAP10c_2322"
     CDS             complement(146..418)
                     /codon_start=1
                     /locus_tag="PAP10c_2322"
                     /product="hypothetical protein"
                     /protein_id="KPA06467.1"
                     /transl_table=11
                     /translation="MQKNISKTMHSEWVLRNSLYWMSTVTRWRLDENDQNWIVSFEHWN
                     DEVEFEFERLLNDYKLREKLQAHTGQVRTSIIDNVLRSIDTRLAE"
     gene            741..995
                     /locus_tag="PAP10c_2323"
     CDS             741..995
                     /codon_start=1
                     /locus_tag="PAP10c_2323"
                     /product="hypothetical protein"
                     /protein_id="KPA06468.1"
                     /transl_table=11
                     /translation="MSEMPAEEVCSTCQQPLHDSVIIEKDGEVLKSCPSCSSKAGTHFF
                     YKHDDFGMRNMGDGRFIVQSWCLGCRSQDGMKPKLAFKC"
     gene            1209..3050
                     /locus_tag="PAP10c_2324"
     CDS             1209..3050
                     /codon_start=1
                     /locus_tag="PAP10c_2324"
                     /product="hypothetical protein"
                     /protein_id="KPA06469.1"
                     /transl_table=11
                     /translation="MKTRSFSIFLLKAGYNAQNSLKPDHQLLDDFEAQNLPQGASLFIS
                     DRFKTTPWWVNYFSIGGNLEQESKGSLIFLPVRNRCFALTFGHIYHNLLDVSYEYDFGL
                     KVTLNSLEPNELKSADIVDPGASRRKRMQVPVMSDLTYLDFDSNSEILKSLTGKVKPQY
                     IELFKNATGSTNLKVGLKLEPNELIVLCDQLLDLYASNEYLETFPNIQKIVPEKDPVKI
                     ERLDTSLLEAFVDRSDELSLSIPDIVDYSDNIYCVFKGRKGISPIYTDISLDEFYNYLE
                     GVDLNTFDIEKIKSFSLNLCNEEGITSKAYNIYRSFIYDIPFGDEGVVYHLCEGEWYKV
                     DQEYLATLKDYIDQRCENTSLPPYNHDNVAANIRSYSEENYNEDVARKSLTHICLDQTD
                     ISPDGYTQIEPCDIISYNGNKCIFHHIKISSRSSQLSHLFNQGVNSIELLILEGHSRDK
                     LKNLIKEKIEHRDLDSFKRAIDGNEYKVEFGIITKKNAMSKSENLPLFSKISLMRSLRA
                     LALYRTEGVVSFIQDTSPPKESYSKYPRITVVVSLGANGKNEVVVDNNQTFPQGKKVMR
                     CSQEITNSAIGSKYMIYVKASENGDLSTSHAWESELI"
     gene            3678..3950
                     /locus_tag="PAP10c_2325"
     CDS             3678..3950
                     /codon_start=1
                     /locus_tag="PAP10c_2325"
                     /product="hypothetical protein"
                     /protein_id="KPA06470.1"
                     /transl_table=11
                     /translation="MTNSNSGEEKKKEIVTEEKIIPANSKKNIGVYKLIDIVILTIVII
                     GTGFLLYFFFKRHINDVAENKTAVNLILSSLPVLSGGLLISLWFT"
     gene            4760..5152
                     /locus_tag="PAP10c_2326"
     CDS             4760..5152
                     /codon_start=1
                     /locus_tag="PAP10c_2326"
                     /product="hypothetical protein"
                     /protein_id="KPA06471.1"
                     /transl_table=11
                     /translation="MEKINIIFDDEFPSSFTNNPVAKKLPPNRLRRYSVTVRLNEVEMS
                     KVNQSRGQLSRSCWLRSSALQQLPPSVPVINRDAWHELTASLQKFNDLTSFLNRRGSDA
                     QPLSKEVDTLRLKLSHVKDALLSLDK"
     gene            5682..6293
                     /locus_tag="PAP10c_2327"
     CDS             5682..6293
                     /codon_start=1
                     /locus_tag="PAP10c_2327"
                     /product="relaxase"
                     /protein_id="KPA06472.1"
                     /transl_table=11
                     /translation="MMEARSGIKAPKKIIQEAIEAVLSFYGTITIDDFVYELSKLKITA
                     KASIASTGKMNGFSFEYAGIAFKASQLGKTYSWSSLSKRVILPPAVEPQVIADTELPEE
                     ELVAVERLANIDDEPMFHSPAIPYIEELNTKQNGRVRWLLWVPYLKQIIQAFKATGLSI
                     LKPSIKMKPFHFVTPTQNLGGKESLAIIKESATGKKRFSI"
     gene            6600..7181
                     /locus_tag="PAP10c_2328"
     CDS             6600..7181
                     /codon_start=1
                     /locus_tag="PAP10c_2328"
                     /product="hypothetical protein"
                     /protein_id="KPA06473.1"
                     /transl_table=11
                     /translation="MTTMTEVKQPNFLMMKRVWIAIALPIVIFYFLGMRGLVQLAIIWV
                     FASIMLLMFAYKKFRIKKWNASTRDHFGEQDGMWSHEFGSTFMKLDQQRGLIHLKEENK
                     QKTYPFSAIKEWRYNLSTTRERAGMNKELDRTHDFRESGFYISIDDVQYPEWRVMFFPQ
                     KGDFNSQEGIRDTELQLKRWMHVFDKIINK"
     gene            complement(7262..8356)
                     /locus_tag="PAP10c_2329"
     CDS             complement(7262..8356)
                     /codon_start=1
                     /locus_tag="PAP10c_2329"
                     /product="hypothetical protein"
                     /protein_id="KPA06474.1"
                     /transl_table=11
                     /translation="MKTVYILGAGFSVDAGAPTQQSIISKAFDLNEQDESNFDKCKFEI
                     FRDFIVDQLNVEFDNAGKVDLEDIFTPLDRCINENSQYRGVSVKSLADVREATFYVVGK
                     TIQLLLNKTTNNKDYIDLFAKSLISHSRRKKGNNYPQVDPVSVISTNWDILLDNSVYHE
                     ILKSKEDAVVDYCCYISSLTKEDKTVKPGLEVLGRGGYNVKILKVHGSLNWLQCPRCMR
                     LYVSFPNKEAIYNFQQPSSCRHCDHNFPEEIGNHNLYSNLIMPTFIKDLTNPQYKIVWQ
                     NAGVEISEADKLVFIGYSLPSADFDMRQLLSRMTRKSAEIEVVDKCNDPEDISNKEAHW
                     RKFFGKRDISFHFNGASDYLSKIS"
     gene            complement(8432..9322)
                     /locus_tag="PAP10c_2330"
     CDS             complement(8432..9322)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1166:transporter,
                     EamA family (Score: 130.2; E-value: 1.6e-39)"
                     /gene_kind="transport"
                     /locus_tag="PAP10c_2330"
                     /product="protein PaaC"
                     /protein_id="KPA06475.1"
                     /transl_table=11
                     /translation="MTKSSLWLTMLMALIWGTSFPVSKIAINVIGPYAFRMAGSLVSCG
                     IIFLIFNKSIRESLKTLNFDEFLRIAIIAVPNVFLVPTLNSIALHFTSVTNATILVYTM
                     PCFTSIILMGLARKLNLLSLFSLLLCFSGIFLILKEVHVGLGEIVILCSAIFWAIGAVV
                     SQKIVTVTPFKARLFWQILVSTILVSITYPFFQSGPLLQPLVTAFTNTECLLCVLYLGI
                     VGNALVYFIWFYLIQNESAEFASYATLLSPVITVIIASTFLNEQPTSKQVIGFSLILMS
                     ALLVNVIRPFFAKGK"
     gene            complement(9327..10004)
                     /locus_tag="PAP10c_2331"
     CDS             complement(9327..10004)
                     /codon_start=1
                     /locus_tag="PAP10c_2331"
                     /product="2OG-Fe(II) oxygenase"
                     /protein_id="KPA06476.1"
                     /transl_table=11
                     /translation="MSIDSITFNDKGYLTKNIQSQFASKIYEIMESSQDSSEECWTYIY
                     KNSLEQKDLSFLTPADEIEKSFNSCFADFCDNKFSFFFRRLSNEVKDNVASSEASIIAY
                     NFCNSEEFKDLIARLTGRKIGNTDLFYINRFDKGHFLNTHTDSGNNVGVALNITQNWDP
                     NFGGLTHILDQDRKKVVDTLTPGFAELFLFDTSEKQVPHFVSMVTANQKSRRMSVIARY
                     GKA"
     gene            complement(10001..11122)
                     /locus_tag="PAP10c_2332"
     CDS             complement(10001..11122)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Pantocin_Microcin_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ThiF"
                     /gene_kind="biosynthetic"
                     /locus_tag="PAP10c_2332"
                     /product="thiamine biosynthesis protein ThiF"
                     /protein_id="KPA06477.1"
                     /sec_met_domain="Pantocin_Microcin_RRE (E-value: 8e-21,
                     bitscore: 63.9, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="ThiF (E-value: 7.5e-37, bitscore: 116.7,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLTNVKPLIKESHHIILADDGDICIGEIPGVSQVINDPPSWVRP
                     ALAKMDGKRTVPRIFKELVSEGVQIESEHLEGLVAGLAERKLLQDNSFFSKVLSGEEVE
                     RYNRQILQFSLIDADNQHPFVYQERLKQSKVAIFGMGGWGTWCALQLAMSGIGTLRLID
                     GDDVELSNINRQVLYRTDDVGKNKVDAAKDTILAYNENVNVETFFEFASPDRARLEELV
                     GDSTFIILAWAALGYYRKDTAEEIIHSIAKDKAIPVIELGGDPLEISVGPIYLNDGVHS
                     GFDEVKNSVKDKYYDSNSDIRKFQEARLKHSFIDGDRKVNAWQSAPSLSIMAGIVTDQV
                     VKTITGYDKPHLVGKKFILSLQDFRSREEEIFK"
     gene            complement(11178..11270)
                     /locus_tag="PAP10c_2333"
     CDS             complement(11178..11270)
                     /codon_start=1
                     /locus_tag="PAP10c_2333"
                     /product="hypothetical protein"
                     /protein_id="KPA06478.1"
                     /transl_table=11
                     /translation="MIKFSTLSQRISAITEENAMYTKGQVIVLS"
     gene            complement(11790..12203)
                     /locus_tag="PAP10c_2334"
     CDS             complement(11790..12203)
                     /codon_start=1
                     /locus_tag="PAP10c_2334"
                     /product="hypothetical protein"
                     /protein_id="KPA06479.1"
                     /transl_table=11
                     /translation="MDKLQKYLPDQRFLILLNRFIIRYDESQCNKDKVVKDAYLFCVGY
                     FLKYQQDYENPYLRGPSNIIAILSSALLSPSFYAIPSSISLDRILYFYKFIIEYIIWNE
                     YEVETVFRTHKLSIRKDIPYEIKDPSSRKKKRL"
ORIGIN
        1 attcgtgagg tggtttgctc tggaggaaag ttattattgg caagaagatg tagctcatcg
       61 tcatcgacga agctgtgaaa gccagcaaga ttgctgatga agactttgcc atcgctaagg
      121 cggtcgaagt cgaatggcat cgtattcatt cggcaagtct cgtatcgatg ctcctcagaa
      181 cattatcgat gatagaagtc ctgacctggc cggtatgagc ctgaagcttc tccctgagct
      241 tgtaatcatt cagcagtcgt tcgaactcga actcaacctc gtcgttccaa tgttcaaacg
      301 aaacaatcca gttttgatcg ttttcatcaa gcctccagcg ggtgacagta ctcatccagt
      361 aaaggctatt cctcaacacc cattcagaat gcattgtttt tgatatgttt ttttgcataa
      421 cattaccacc cagaaagtat caaagaagga atccaaaaat tttagttatc tttcaaaaaa
      481 agcaataaac ttcgaaaaac atgaccataa acagcaacaa ccaacaacta tctgttttta
      541 ctgaatttta ttttgttaag ttacagaata ttcttatact gcaataataa tcatcatgtt
      601 ttagaatgta aatttgtttt gaaaactttt attactcatg ccaatataat tacattaact
      661 tatgatttga ttgcatttcg accaacaaag cctgatgtct aatccattga tttaatatgt
      721 aattatggag agtcaacaaa atgtctgaga tgccagcgga agaggtatgt tccacatgtc
      781 aacagccact gcatgattct gtgatcattg agaaagatgg cgaggtgtta aaaagttgcc
      841 cttcatgttc cagcaaagca ggcactcatt ttttctataa acatgatgat tttggtatgc
      901 gaaatatggg tgatggtaga ttcatcgtgc agtcttggtg tctaggatgt agatcacaag
      961 atggtatgaa acctaaatta gctttcaaat gttagtcatt atttaagaga taatctttgg
     1021 tgagcgctac agtaaaattc ataacaattg aaataaataa agatattctc acctaccgca
     1081 attggctatc ggagccttta gatggcggca tgtttgacct atatcattaa taagatgagt
     1141 taaaatttaa actgtcttca aatataagta actcaaaaac tgtttacctc tcaaagggct
     1201 aaaatgatat gaaaacaagg tctttttcta tttttttgct taaagcaggc tacaacgcac
     1261 agaactccct taagccagat catcaacttc tcgatgactt tgaagctcaa aatctcccac
     1321 agggtgcaag tttatttatt tctgacagat ttaaaacaac tccttggtgg gtaaattatt
     1381 tctcaattgg tgggaattta gagcaagaaa gtaaggggtc attaattttt cttccagtta
     1441 gaaaccgatg tttcgcacta acgtttgggc acatttatca caatttactc gatgtttcct
     1501 atgagtatga ctttggtctt aaagtaacat taaacagcct agaacctaat gagttaaaaa
     1561 gtgctgacat agtagaccca ggtgcatcaa gaagaaaaag aatgcaagtt cctgtcatgt
     1621 ctgacttaac ctatttggat tttgacagta atagtgagat tttaaagagt ctaacaggaa
     1681 aagttaagcc acaatacatt gaactattta aaaatgcgac tggctcaaca aatttaaaag
     1741 taggtctaaa attagaaccg aatgagctta tagttttatg tgatcaacta ctggatttat
     1801 atgccagtaa tgaatattta gagactttcc ctaacataca aaagatagtg ccggaaaaag
     1861 accctgtaaa aatagaaagg ttagacactt cacttttaga ggcatttgta gatcgaagtg
     1921 atgaattatc cttatcgatt ccagatattg ttgattatag tgacaatata tattgtgtat
     1981 tcaaaggaag gaaaggaatc tccccaatct atactgacat tagtcttgat gaattttata
     2041 actatctcga aggggttgat ttaaatacat ttgatataga aaaaataaaa agcttttcat
     2101 taaacctctg taatgaagaa gggattacct ctaaagcata taatatttac agaagcttta
     2161 tttatgatat tccctttggc gatgagggag ttgtttatca tctctgcgaa ggagaatggt
     2221 ataaagttga tcaggagtat ctagcgactt tgaaagatta tatcgatcaa agatgcgaga
     2281 acacctcact cccaccatat aatcacgata acgtagcagc aaacataaga agttacagtg
     2341 aagaaaacta taatgaagat gttgctcgta aatcacttac acatatctgc cttgatcaaa
     2401 ctgatataag ccctgatgga tatacgcaaa tagagccttg tgacataatc agttataatg
     2461 gaaacaagtg cattttccac catattaaaa tatcatcacg ttcatcccag cttagtcatc
     2521 tctttaatca gggtgtcaac tccatagagt tgttaatttt ggaaggacac agcagagata
     2581 aattaaagaa tcttattaaa gaaaaaatag aacatcgtga tttagatagt tttaagcgag
     2641 caatcgatgg aaatgaatac aaagttgagt ttggtataat tacgaaaaaa aatgcaatgt
     2701 ctaaatctga aaaccttccc cttttttcaa aaataagctt aatgagaagt ttaagagcac
     2761 ttgctcttta ccgtacggaa ggtgtggtaa gttttataca agatacaagt cctcccaaag
     2821 aaagctatag taaatatcct cgtattacag tagtcgtatc tcttggtgca aatggtaaga
     2881 atgaggttgt tgtagacaat aaccaaactt tcccccaagg gaaaaaagta atgagatgct
     2941 ctcaagaaat aactaatagt gctatcggtt caaaatatat gatttatgtc aaagcaagcg
     3001 aaaatgggga tcttagcacc agtcacgctt gggaaagtga attgatctag ataaataggc
     3061 ttattgaaaa gggaacacac accatagcct cgtaaattcg acggggcttt tctgtatttt
     3121 aatatgaaca gctgaatgtt acctttatct aattatttat taactcattt gattttaaaa
     3181 gcatcagaca ccgtagcgaa accatctttg caaacaaatg gtgcaagttt cattagctct
     3241 aatgtaacgc tctcaagaat agcatacaga gccgctgatg aatgatcttt gctatatcag
     3301 ttttctgtct cgccagaacc gcagatatgt ccaacaaaaa gagtgtgctt ttcgctgtca
     3361 attcctgctt ttttgagctt ggtagaaaac gtgtgactgg atgaatgaga agatttatgg
     3421 ctaatttata aattctaata gcactatcaa cagcttacgg ttaaaccagt ccgaagcctt
     3481 taaaatcttt tctatctcgt taccagccaa aaaacattag caaaatcaat tcatttattt
     3541 tacattggtt gaatattggt gttttctgct taaacgtacg taggaatttt gcaaaacatt
     3601 caactttggc atgtaaattt tactacagtt cgctacaccc ttatgaactt tatcatctaa
     3661 tatttgggag aggaaaaatg acaaattcaa attctggtga agaaaaaaag aaagaaatag
     3721 ttactgaaga aaaaatcatt cctgcaaata gtaaaaaaaa tataggcgta tataaactta
     3781 ttgatatcgt tattttaact attgtgataa ttggcactgg gtttttattg tattttttct
     3841 ttaaaagaca cattaatgat gtggcggaaa ataaaacagc agtaaattta attttatcat
     3901 cccttccagt tttatctggc ggattgctaa ttagtttatg gtttacttaa cgtggaaagt
     3961 ctgtcaagtt tctaaatgac tttttccttt tctcatccgc atcatttttc acatacttat
     4021 ccttatttgg tgacggactt gcaagcataa cccctgacaa cacagataaa ttaaatattc
     4081 ttttgataaa gacaataata aatgtcatgc ttttaatttc ttcaacaggt aagacattta
     4141 ttacagcact tgaattcata acagaaagaa attccgagac agaaatctca gttaaatcag
     4201 atcaaaaaga taaaccccaa gaaaaaccac ttaaaaaaga aaagggaata tggttttatt
     4261 tactttttgt tactgcatgt gttgtattgt catcacttcc tttagttagt gataaaataa
     4321 ttaattactt tcatgtagct acgaattatt tgtcagcttt gacatcaacc atgaaataaa
     4381 gaacatgaag atataaaaat caatagcaaa aataacaaca ctaaattctt ttagcggaaa
     4441 aattagtagt aatttattat taaaactaac aacagaaata gattatactt taccatctta
     4501 gaccccacca gttatttaca tatattttat ataatcaata aatattttat gtcaatagct
     4561 tcattattta agcaagggct aactcataga tgctccgcat ctttgagttg ccttgctttt
     4621 tccgcccttc ggttgaaaaa gaaagatcta aaccactaca taatcaaaac ccaacccatt
     4681 gacactattg atgtttatgg tatttattac atatagcata cggatttgct attaagctta
     4741 aatatcaaaa ggagttgata tggaaaaaat aaatattatt ttcgatgatg agtttccttc
     4801 ttcgtttacc aataatcctg tcgcaaagaa gttaccccct aatcgtcttc gcagatactc
     4861 agtgactgtc agattaaatg aggttgagat gagcaaagta aaccagtcca gaggacagct
     4921 aagcaggagc tgttggctga gatcttcagc tcttcagcaa ttacctccct ccgttcctgt
     4981 gataaatcga gatgcatggc atgaactaac agcttctctg caaaagttta atgacctaac
     5041 ttcgtttctt aatcgtcgcg gatctgatgc tcaacctttg agtaaggagg ttgatactct
     5101 caggctgaag ctgtcgcatg tgaaagatgc cctgctatca ctcgataagt aactatcagc
     5161 tcatgaaggg aatgcagaaa attcgtagag gtaagtgctt caaaggtatc gtctcatatg
     5221 cacttgcccc agcacctcat cataagacag ccccggtgat aatcggcggt aacatgattg
     5281 gcttatctgt ggatgaagtg actgttgagt tcatgcgaac acagcagctc cggtcagatg
     5341 tgcagaaacc tgtctggcac aactctcttc gccttcctaa aggagattca ctcactgatg
     5401 agcaatggaa gcttgttgct gacgactata tgaagcgaat gggcttcagt gatactcatc
     5461 tccgttgcta tatcatgcat aatgacgagg ccggccagca catacacata attgcttctc
     5521 gcatccgtat acctgatggc caactctacc ttggtagaaa tgagaacctc atcagcacca
     5581 aaatcattca acagcttgag cgggatcatc tgcttacacg aaccaaaggt ccatctcctc
     5641 cttcagcacc caaagtcagg aaaactggca ggaatgaaga aatgatggaa gcaaggtcag
     5701 gcattaaagc tccaaaaaaa atcatacagg aagcaattga ggcggtgctc agtttctatg
     5761 gcaccatcac cattgacgat tttgtttatg aactcagcaa gctaaagata acagccaaag
     5821 cgagcattgc ttccacgggt aaaatgaatg gcttctcatt tgagtatgca ggaatcgcct
     5881 tcaaagcatc tcagttaggt aaaacctact catggtcgag cctgagtaag agggttatcc
     5941 tcccccctgc tgtcgagcct caggtgatag ctgatacaga gttgcctgaa gaggagttag
     6001 tagcagtgga aagactggcg aacatagacg acgagccaat gttccactcc cctgctattc
     6061 catatattga ggagctgaat actaaacaga acggcagggt tcgctggcta ctatgggtcc
     6121 catacctgaa gcagattatc caagccttta aagcaacagg tctgagcatt cttaagccgt
     6181 caatcaagat gaaacctttc cacttcgtta cccccaccca aaaccttggc ggtaaagaat
     6241 cactcgcaat catcaaagaa agcgctactg ggaaaaaaag attttctatt tgatgcctct
     6301 taaacctgct agttatcagt agcttaaaac tacacattaa gtcaaatgcg ctatctattc
     6361 ttattaataa tcatattgat aggaaaaacc gatcgatcgt ttttacagat caattttaat
     6421 atcatgatag tctttatcta tcaaaaagat ctgatcgatc ggtacaaatg atttgctaga
     6481 cactcattac tggccgtaat gtaacttcaa acgaagcgat atagctcact gatttatcag
     6541 caaaataagc tgaagggtca gtgcgctcca aatccaacga aacgataccg gatggtctta
     6601 tgacaacaat gactgaagtt aagcaaccta attttctgat gatgaaaaga gtatggattg
     6661 ccatcgctct gccaattgtc atcttctact tcttaggtat gagaggatta gtgcaactcg
     6721 ctattatttg ggttttcgca agcatcatgc tcttgatgtt tgcctataaa aaattccgca
     6781 tcaaaaagtg gaatgccagc accagggacc attttggcga gcaagacggt atgtggagtc
     6841 atgaatttgg ttctacgttt atgaagctcg accagcaaag aggactaatc catcttaagg
     6901 aagagaacaa acaaaaaacc tatccgttct cagcaatcaa agagtggcga tacaatttgt
     6961 ctactacgag agaacgggca ggtatgaaca aagaacttga ccgaacacac gattttagag
     7021 agtcaggctt ttacatctct atcgatgatg ttcaatatcc agaatggcga gtaatgttct
     7081 ttcctcaaaa gggtgacttc aactcacaag aaggtatccg ggatacggaa ctgcaactta
     7141 agcgatggat gcatgttttt gataaaatca tcaacaaatg ataactagat ttttttgagc
     7201 cagcattttg ctggctcagc tcagtaaaaa ttacgatcat atagaattaa aataggaaaa
     7261 atcaacttat cttgctgaga taatcggaag ctccattaaa gtgaaatgaa atgtctcttt
     7321 taccaaaaaa ctttctccaa tgagcttctt tatttgaaat atcctctgga tcattacatt
     7381 tatcaacaac ttcaatctca gcactttttc ttgtcattct tgataaaagt tgtctcatat
     7441 caaaatctgc actcggtaat gagtatccta taaaaactaa tttatcagct tcagaaattt
     7501 caactccagc attttgccag acaattttgt attgaggatt agttaaatct ttaatgaaag
     7561 ttggcattat caaattggaa taaaggttat gattgccaat ttcttcagga aagttgtgat
     7621 cacagtggcg acatgaactt ggttgttgaa aattataaat tgcttcttta tttggaaaac
     7681 ttacataaag cctcatacaa cgaggacatt gtagccaatt taaggagccg tgaactttaa
     7741 gaattttaac gttataaccg cctcttccaa gcacttctaa tccaggtttt accgttttat
     7801 cttctttagt caacgaacta atatagcagc aataatctac aacagcatct tccttacttt
     7861 ttaggatttc atgatagaca gaattatcta ataaaatatc ccaattcgtg ctaatcacac
     7921 tcactggatc aacttgagga taattattac ctttctttct acgggagtga gaaatcaagc
     7981 ttttagcaaa taggtcgatg tagtctttgt tattagtggt tttatttagt aataattgta
     8041 ttgttttacc tacaacataa aaagtagcct ctcttacatc agctaaactt tttacactca
     8101 cacctctata ttggctattt tcgtttatac accgatccaa tggggtaaat atatcctcta
     8161 aatccacttt cccagcattg tcgaactcaa cattgagttg atcaacaata aaatccctga
     8221 aaatttcaaa cttacattta tcaaagttac tttcatcctg ttcattcaag tcgaaagctt
     8281 tggaaattat actctgctga gttggtgctc cagcatcaac agaaaaccca gcacccaaaa
     8341 tgtatactgt cttcattata tataactcac tttttcaaaa tatattttat agaatttaac
     8401 aataatgagt caccatttaa taaaagataa ctcattttcc ttttgcaaaa aatggtctaa
     8461 taacatttac caaaagagca ctcatcaaaa tcaggctaaa accaattact tgcttgcttg
     8521 taggttgttc attgagaaat gtagaagcaa taataacggt tataacaggt gatagcagag
     8581 tcgcatagct tgcaaattct gcactctcgt tctgaatgag ataaaaccag atgaagtata
     8641 ccagtgcatt acctacaata ccgagataga gaacacaaag aagacattca gtattagtga
     8701 aagcggtaac aagaggttgt agtaatggac ctgattggaa gaaaggataa gtaatggaaa
     8761 ccagaatagt tgaaaccaat atctgccaga atagcctggc cttgaaggga gtaacagtca
     8821 ctatcttttg agaaacgaca gctcctatag cccagaaaat ggcactacat agaattacaa
     8881 tctcacccaa tccaacatgt acttctttga gtatcaaaaa aatccccgaa aaacaaagaa
     8941 ggagtgagaa cagggagagt aagttcagct ttcttgccaa gcccatcagg ataatcgagg
     9001 taaagcaagg cattgtgtaa acaaggattg tcgcattcgt aacagaggtg aagtgaagag
     9061 cgatgctatt gagtgttgga accaggaaaa catttggcac cgcaattatt gcgattctta
     9121 aaaattcatc aaagttaagg gtcttaaggc tttcacggat acttttgttg aatatcaaaa
     9181 aaataatacc acatgaaaca agagaacccg ccattcggaa tgcataaggg cctatcacat
     9241 taatcgcaat ttttgaaaca ggaaatgaag tgccccatat taaagccatt aacatcgtaa
     9301 gccataaaga acttttagtc attaatctaa gccttcccat accttgctat aacagacatc
     9361 cgcctgcttt tctgattagc tgtaaccatc gatacgaaat gaggaacctg tttctctgat
     9421 gtatcaaaaa gaaacagctc agcaaaacct ggagtcaatg tatcaacaac cttctttcta
     9481 tcctgatcaa ggatatgtgt taaaccacca aagttcgggt cccaattttg agtaatgttc
     9541 aaggctaccc cgacattatt ccctgaatcc gtatgggtgt tgagaaaatg gcctttatca
     9601 aaacgattaa tgtagaaaag atcggtattt cctatcttcc tcccggttag gcgagcaatc
     9661 agatctttaa actcttcgga attacaaaaa ttatacgcga ttattgaagc ttcacttgaa
     9721 gcaacattat ctttcacttc attggagagt cttctgaaga agaaactgaa tttattatcg
     9781 caaaaatctg caaaacaaga gttgaaactc ttttcaatct catcagccgg ggtcaaaaat
     9841 gaaagatctt tttgctctaa ggaatttttg tatatgtaag tccagcactc ctcagatgaa
     9901 tcttgtgacg actccataat ctcatatatt tttgaagcga attgagattg tatgtttttg
     9961 gtaagataac ctttgtcgtt aaaggtaata ctatcaatgc tcatttaaaa atctcttctt
    10021 cgcgagacct gaaatcttgc aatgaaagaa tgaatttttt acctacaagg tgtggtttat
    10081 cgtagccagt tatggttttg acaacctgat cggtaacgat accagccatg attgatagtg
    10141 agggagcact ttgccaggca tttaccttcc tgtcaccatc tatgaacgag tgcttcaggc
    10201 gggcttcctg aaactttcta atgtctgaat tgctgtcgta atacttatcc ttaacagagt
    10261 tcttaacttc atcgaacccg ctgtgaacac catcattgag gtagatggga ccaacggaga
    10321 tctctaaagg atcaccaccc agctcaataa cagggatggc tttgtcttta gctatgctat
    10381 ggatgatttc ttcagcagtg tccttacgat agtaacccag tgctgcccag gcaaggatga
    10441 tgaaagtgct gtcaccaacg agttcttcaa gtcttgctct gtctggagaa gcgaactcaa
    10501 agaatgtctc cacattcacg ttttcgttat aggcaaggat cgtatctttg gccgcatcaa
    10561 ctttgttctt gcctacatca tctgtgcgat acaacacctg tctgttgatg tttgacaact
    10621 cgacatcatc cccatcaatg agtcttaagg tgcctatacc tgacatagcc agttgaagtg
    10681 cacaccatgt gccccatcct cccatcccga agatggctac cttactttgc tttagccgtt
    10741 cctgatacac gaaaggatgt tggttatcag catcgatcag ggagaactga aggatttgcc
    10801 tgttgtacct ttctacttcc tcaccagata gcacttttga gaagaaggag ttgtcctgaa
    10861 ggagcttcct ttccgccaag cccgcaacca gtccttccag atgttcactt tcaatctgga
    10921 caccctcact aaccagttct ttaaaaatcc ggggaactgt ccttttacca tccattttgg
    10981 caagagctgg tcttacccag gaaggaggat cattgatgac ctgagatact cctgggattt
    11041 ctccaataca aatatctcca tcatctgcga ggatgatgtg atgagattct ttaatgaggg
    11101 gtttaacatt cgtcagtgac atggtgtgct ccaaaaaagt aaggccgcat acgagatgcg
    11161 gcctttgtca tacgttatca gctaaggacg ataacctgac ctttggtata catagcattt
    11221 tcttcagtga tagcagaaat gcgctgagac agagtagaga acttgatcat agtgataccc
    11281 tcttgcttgt tcagttaggt ttgtaaagtt gtgtttgtgt atcgatacca ctccaataaa
    11341 caacattaat gatttactcg tcaataaccc tagccgtaaa aagccatact cttttttaat
    11401 ttaaaatctt aaaagaataa acctctggct ttgcaggaaa tatccggagt taagataatg
    11461 cagatgatgc ttttatcagc attttattaa catgtactta aaaagtgcaa cttgaaaaaa
    11521 actcattagt aacccttaga aatagttaga atgtttactt agtgggtgaa cttatgacag
    11581 cagggttcag ggttcagggt tcagggttca gggttcaggg ttcagggttc agggttcagg
    11641 gttcagggtt cagggttcag caggaagcag gacaagtgag tgaggtgctg taaatgctta
    11701 aaaaaatggc ctatatgccc cccctttgag aaaatcgaaa agccattgtt gaagaagtta
    11761 ttaacctggg attaagtaat gaaaagttat tacaacctct ttttcttacg agaagatggg
    11821 tctttgattt catagggaat atcttttcta atacttaatt tatgagttct gaacacagtc
    11881 tcaacttcat actcattcca tattatgtat tcaataatga atttataaaa atatagaata
    11941 cgatcaagac taatactcga aggtattgca tagaagcttg gactaagtaa agccgaactc
    12001 aaaatagcaa taatgttgct gggccctctt agataaggat tttcgtaatc ttgctgatat
    12061 tttaagaaat aacccacaca gaaaagatag gcatctttaa caactttatc tttattacat
    12121 tgtgactcat cgtatcgtat gataaatcga ttaagaagaa tcaaaaacct ttggtcaggc
    12181 aaatattttt gtaatttatc cataataagc atccttgcta agttgtcatc cttgacatgt
    12241 tacttataac gcatatgacc taaaaatcaa tagctacact atcttcgaaa cttttcaata
    12301 attgctttca aaccatttaa aaaacctc
//
