LOCUS       BGC0002320              7143 bp    DNA     linear   PLN 27-FEB-2015
DEFINITION  Penicillium chrysogenum Wisconsin 54-1255 complete genome, contig
            Pc00c20.
ACCESSION   BGC0002320
VERSION     BGC0002320
KEYWORDS    .
SOURCE      Penicillium rubens Wisconsin 54-1255
  ORGANISM  Penicillium rubens Wisconsin 54-1255
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Penicillium; Penicillium chrysogenum species complex.
COMMENT     ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2024-10-17 17:19:20
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 2509977
            Orig. end    :: 2517120
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     subregion       1..7143
                     /aStool="mibig"
                     /contig_edge="False"
                     /label="terpene"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..7143
                     /contig_edge="False"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     exon            complement(4..471)
                     /gene="Pc20g10860"
                     /locus_tag="PCH_Pc20g10860"
                     /number=1
     gene            complement(<4..>2798)
                     /gene="Pc20g10860"
                     /locus_tag="PCH_Pc20g10860"
     mRNA            complement(join(<4..471,530..614,668..728,781..888,
                     936..1096,1151..1305,1417..2050,2100..2334,2507..>2798))
                     /gene="Pc20g10860"
                     /locus_tag="PCH_Pc20g10860"
     CDS             complement(join(4..471,530..614,668..728,781..888,
                     936..1096,1151..1305,1417..2050,2100..2334,2507..2798))
                     /codon_start=1
                     /db_xref="GOA:B6HFX8"
                     /db_xref="InterPro:IPR000092"
                     /db_xref="InterPro:IPR008949"
                     /db_xref="InterPro:IPR017446"
                     /db_xref="UniProtKB/TrEMBL:B6HFX8"
                     /gene="Pc20g10860"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: fung_ggpps2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182:Polyprenyl synthetase (Score: 219.3; E-value:
                     1e-66)"
                     /gene_kind="biosynthetic"
                     /inference="protein motif:COGS:COG0142"
                     /inference="protein motif:PFAM:PF00348"
                     /inference="similar to AA sequence:PIR:S15662"
                     /locus_tag="PCH_Pc20g10860"
                     /note="Title: strong similarity to geranylgeranyl
                     pyrophosphate synthase al-3 - Neurospora crassa"
                     /protein_id="CAP86415.1"
                     /sec_met_domain="fung_ggpps2 (E-value: 1.3e-101, bitscore:
                     325.9, seeds: 17, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADKITDEYAVGIDPEIYANNPAYSSLFNPYIHKQTIIADHVSVQ
                     CHIDLNGIDAVGSKFGNLNAHAGNFTSLCAPNCLPERFALVAYTVEYAFLHDALNQSGM
                     TSVSTRVSDKAQRKSEVQAKIAAEYLRLDPVFGEWFLNKWQTFTACVKDVRSLEFPSLD
                     DYLEFRIVDAAADWTLYNFRWGSGITLTPEEEKIADPMSYVAYAELCLVNDLFSWDKEY
                     ASHIKSNGDVPLVNAVHIVAVTQGLTHCAAKAVVQAEVRAHEERFCQLKEQYEATDKPS
                     HEVLRWLRLLEHSMAGNWVWSLCVPRYCKVDRNPYKDHLEKYGSDAVRVLTPLDRLCWP
                     KQEIKDMKQSELKDPSSSTYKSHFSPLEPNPGPEQMRLTISQTQQQRPVLNPYTYINSL
                     PSKNVRQTLIAALNSWYKVPVKSLLIIEGAVNFLHNSSLLLDDIQDGSFLRRGRPVAHQ
                     IFGVGQTINTATYLMNEALYLIQMLSPSAVSVYTEIDEMRNLQLGQGRDLYWSYHTHVP
                     TPAQYISMVDGKTGGLFRLISRLMRSEATKNSDLDISQFATLLGRHFQIRDDYQNLQSE
                     DYTKNKGFCDDLDEGKLSFPIILSMQSPGFSNTALSSVFKGSQKGQTLSLEMKQYMLEE
                     ITARGAFSETKAVLRKLHTELLRLLIETEKKAGGVENWALRLLIMKLDIAEEKKVAPPK
                     SDSHWGVNQRRAWKGCQKNGRPIDKACFLRAMEETLQK"
     intron          complement(472..529)
                     /gene="Pc20g10860"
                     /locus_tag="PCH_Pc20g10860"
                     /number=1
     exon            complement(530..614)
                     /gene="Pc20g10860"
                     /locus_tag="PCH_Pc20g10860"
                     /number=2
     intron          complement(615..667)
                     /gene="Pc20g10860"
                     /locus_tag="PCH_Pc20g10860"
                     /number=2
     exon            complement(668..728)
                     /gene="Pc20g10860"
                     /locus_tag="PCH_Pc20g10860"
                     /number=3
     intron          complement(729..780)
                     /gene="Pc20g10860"
                     /locus_tag="PCH_Pc20g10860"
                     /number=3
     exon            complement(781..888)
                     /gene="Pc20g10860"
                     /locus_tag="PCH_Pc20g10860"
                     /number=4
     intron          complement(889..935)
                     /gene="Pc20g10860"
                     /locus_tag="PCH_Pc20g10860"
                     /number=4
     exon            complement(936..1096)
                     /gene="Pc20g10860"
                     /locus_tag="PCH_Pc20g10860"
                     /number=5
     intron          complement(1097..1150)
                     /gene="Pc20g10860"
                     /locus_tag="PCH_Pc20g10860"
                     /number=5
     exon            complement(1151..1305)
                     /gene="Pc20g10860"
                     /locus_tag="PCH_Pc20g10860"
                     /number=6
     intron          complement(1306..1416)
                     /gene="Pc20g10860"
                     /locus_tag="PCH_Pc20g10860"
                     /number=6
     exon            complement(1417..2050)
                     /gene="Pc20g10860"
                     /locus_tag="PCH_Pc20g10860"
                     /number=7
     intron          complement(2051..2099)
                     /gene="Pc20g10860"
                     /locus_tag="PCH_Pc20g10860"
                     /number=7
     exon            complement(2100..2334)
                     /gene="Pc20g10860"
                     /locus_tag="PCH_Pc20g10860"
                     /number=8
     intron          complement(2335..2506)
                     /gene="Pc20g10860"
                     /locus_tag="PCH_Pc20g10860"
                     /number=8
     exon            complement(2507..2798)
                     /gene="Pc20g10860"
                     /locus_tag="PCH_Pc20g10860"
                     /number=9
     sig_peptide     5444..5509
                     /gene="Pc20g10870"
                     /inference="protein motif:SignalP:2.0"
                     /locus_tag="PCH_Pc20g10870"
     exon            5444..5633
                     /gene="Pc20g10870"
                     /locus_tag="PCH_Pc20g10870"
                     /number=1
     gene            <5444..>7131
                     /gene="Pc20g10870"
                     /locus_tag="PCH_Pc20g10870"
     mRNA            join(<5444..5633,5679..6514,6573..6680,6737..6903,
                     6957..>7131)
                     /gene="Pc20g10870"
                     /locus_tag="PCH_Pc20g10870"
     CDS             join(5444..5633,5679..6514,6573..6680,6737..6903,
                     6957..7131)
                     /codon_start=1
                     /db_xref="GOA:B6HFX9"
                     /db_xref="InterPro:IPR001128"
                     /db_xref="InterPro:IPR002401"
                     /db_xref="InterPro:IPR017972"
                     /db_xref="UniProtKB/TrEMBL:B6HFX9"
                     /gene="Pc20g10870"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 291.7; E-value: 1.8e-88)"
                     /gene_kind="biosynthetic-additional"
                     /inference="protein motif:COGS:COG2124"
                     /inference="protein motif:PFAM:PF00067"
                     /inference="similar to AA sequence:PIR:S57337"
                     /locus_tag="PCH_Pc20g10870"
                     /note="unknown EC_number=1.14.-.-; Title: strong similarity
                     to cytochrome P450 trichodiene oxygenase TRI4 - Fusarium
                     sporotrichioides"
                     /protein_id="CAP86416.1"
                     /sec_met_domain="p450 (E-value: 7.3e-51, bitscore: 160.3,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLLWFGFFSFVCGLVIYRLQFHPLSKFPGPKLAALTSLYEFYYN
                     VVLGGRYLWEIERMHEQYGPIVRITPHELHVADPNFYTEIYAGPTRRRDKDPRLVRLAG
                     QPTSMFATVDHGLHSSRRAILNNYFSKRSIAGLEDMIQGKVQKLVKRLNIACDQGTVVQ
                     LDAASSALTADIISEYAHGVSLDYLDDVNFNNEVADSILSLASVVHVLKFFPFLLDLSK
                     FIPDKVLENLWSHAANILRLQKLVRAQADVALQNGGKVNGQATMFGALCDPSLPAQERT
                     LDRLQDEGFSLIGGGTETTTGTLKVIMFHLLNEKALLRKLRKELEESPSGTWAELEKLP
                     YMRGVMNEGLRLSGVITRLPRRAPDEALRYKQWTIPPNSLMSTSSHFVHTNSDLFPDPL
                     VFDPERWIRAEAAGQRLEHMIVTFSKGSRQCMGNHLALAELYLVISTLVREFDMDLYGV
                     TADNIVTHREYGFGVPKERGGGLRVSISRVRTP"
     mat_peptide     join(5510..5633,5679..6514,6573..6680,6737..6903,
                     6957..7128)
                     /gene="Pc20g10870"
                     /locus_tag="PCH_Pc20g10870"
                     /product="unnamed"
     intron          5634..5678
                     /gene="Pc20g10870"
                     /locus_tag="PCH_Pc20g10870"
                     /number=1
     exon            5679..6514
                     /gene="Pc20g10870"
                     /locus_tag="PCH_Pc20g10870"
                     /number=2
     intron          6515..6572
                     /gene="Pc20g10870"
                     /locus_tag="PCH_Pc20g10870"
                     /number=2
     exon            6573..6680
                     /gene="Pc20g10870"
                     /locus_tag="PCH_Pc20g10870"
                     /number=3
     intron          6681..6736
                     /gene="Pc20g10870"
                     /locus_tag="PCH_Pc20g10870"
                     /number=3
     exon            6737..6903
                     /gene="Pc20g10870"
                     /locus_tag="PCH_Pc20g10870"
                     /number=4
     intron          6904..6956
                     /gene="Pc20g10870"
                     /locus_tag="PCH_Pc20g10870"
                     /number=4
     exon            6957..7131
                     /gene="Pc20g10870"
                     /locus_tag="PCH_Pc20g10870"
                     /number=5
ORIGIN
        1 gactcatttc tgaagcgtct cttccatcgc cctcaaaaag caagccttgt caataggccg
       61 cccattcttc tgacatcctt tccacgctcg tcgctggttg accccccagt gagaatcact
      121 cttgggaggc gccaccttct tttcctcagc aatatccagc ttcataatca ataaccgcag
      181 cgcccaattc tctacgcccc cggctttctt ttcggtctct ataagaaggc gcagcagttc
      241 agtgtgcaat tttctcaaca cggcctttgt ttcggagaaa gccccgcgag cagtaatttc
      301 ctccagcatg tactgcttca tctccaggga cagtgtttgg cccttttggg aacccttaaa
      361 cacacttgat aacgcagtgt tggaaaagcc gggagattgc attgataaga tgatgggaaa
      421 agataacttc ccttcgtcga gatcgtcaca aaatcccttg ttcttggtat actgaagcaa
      481 catgttagcc gtggtgcgta ctcagagaca caatatgggg gttagttaca tcttcacttt
      541 gaaggttctg gtagtcatcg cggatttgga agtgtcttcc aagcaaggtc gcaaactgac
      601 ttatatcaag gtcgctggaa caagttagcc tgggtcgcta tatactgtgt gatcaggttt
      661 gaaataccta tttttcgtcg cctccgatct catcagacgg ctgatgaggc ggaataggcc
      721 accagtctct ttaatatgat cagtaagttg ttgtatgagc gtgggtttgc caatacgtac
      781 tgccgtcaac catgctgata tactgcgcag gggtgggtac atgcgtatgg tagctccagt
      841 agagatcacg tccctgtcca agctgtagat tccgcatttc atctatttct gtcaacccaa
      901 aaacctttgc aagcaagtat gtcaggtaac cctaccagtg taaaccgaca ccgcggatgg
      961 cgaaagcatc tgtatgagat acaaggcttc attcatcaga tatgtcgccg tattgatggt
     1021 ttggccaaca ccgaatatct gatgtgccac tggccttccg cgtctgagga aacttccgtc
     1081 ctggatgtcg tcgagtctat tgagaggtca atgaggagaa atgatcccag gttgaattgg
     1141 gcttgcttac aataatgatg agttgtgcag gaagttgact gcgccctcta tgatcaagag
     1201 ggacttcacg ggcaccttgt accatgaatt cagagcagct atcaatgtct gtcttacgtt
     1261 tttagaaggt aaggagttga tataggtgta ggggtttaac acgggctgta gattttagtt
     1321 agtattcaga tcatatcgct ttcagcgact cttgcgggta agaactttcc tcgtcaattg
     1381 acgggtatcc aggggtgtac ctggctagga catcactctc tgttgctgtg tttgagatat
     1441 tgtcagtctc atttgttctg ggccagggtt gggctcaagc gggctgaaat ggcttttata
     1501 cgtacttgag ctagggtctt tgagctcact ctgcttcatg tctttgattt cttgctttgg
     1561 ccagcaaagc cggtctaggg gcgtgagaac tcgcacagcg tcgctgccat acttttcaag
     1621 gtggtcttta taaggattcc tgtcgacctt gcagtaacga ggcacacaaa gactccacac
     1681 ccagtttcca gccatcgagt gctcaagcag tcttaaccac ctaagaactt catgtgatgg
     1741 cttatctgtc gcctcatact gttctttcaa ctgacaaaat cgctcttcgt gtgctcgcac
     1801 ctcagcctga acaactgcct tggctgcgca gtgcgtcaga ccctgcgtaa ctgcgacaat
     1861 atgtactgcg ttcaccaatg gcacgtcgcc attgcttttg atgtgagatg cgtactcttt
     1921 gtcccaagag aacaaatcat tcaccaagca taattccgca tatgcgacgt agctcatagg
     1981 gtcggcgatt ttctcttcct cgggggtgag cgtgatgccc gatccccatc ggaagttata
     2041 gagtgtccag ctttggaata atcagctcag gctctcgagt tgggaaaggg ctcacatact
     2101 ctgctgctgc gtcaacaatt ctgaactcta ggtagtcatc cagactagga aattcaaggc
     2161 ttctgacgtc ctttacacat gcagtgaatg tttgccactt attaaggaac cattcaccga
     2221 acaccggatc aagacgtagg tactcggccg cgatcttggc ctggacctcg gatttgcgtt
     2281 gtgctttatc tgaaactctg gtcgatacgg aagtcatacc gctctggtta agagcttggt
     2341 gaagcatctt attttccagc aacaactaaa tattctgtaa gtttcttgat ccggacaaat
     2401 ggaaagattt ctaggtatca taccgcttct tgatcagcag cattatcggt ttcatctgtt
     2461 cttcagtgtt agttgcagaa aataaacgag cgacggatct acataccatc atgaagaaat
     2521 gcatattcca cagtgtatgc gacaagcgca aatctttcgg gcaggcagtt tggcgcacac
     2581 agcgaagtaa agttacctgc atgggcattg agattgccga acttggaccc aacggcatca
     2641 attccattga ggtctatgtg gcattgtact gagacatgat cggcgattat tgtttgtttg
     2701 tgaatatacg ggttaaagag agaggagtat gccgggttgt tggcgtagat ttcgggatca
     2761 atgcccaccg catactcgtc ggttattttg tccgccatgg tttgcagctg ttgccttgtg
     2821 gattttagaa aataccgacc tgcacaacgc acatataaac gccgaggggt cgcgggtata
     2881 aataatagaa ttcgaaatag aaaaatcgaa tatcctgaga caggtacgct agtttagact
     2941 gatactatcg acgtccgcac ccgatgccgg cttcctcgtt ttctaccgta cgatatccgc
     3001 gcaaggaacc tcgagactag ggttaccacc ttacatctgg caggccccac agcaattaac
     3061 gtgttctaca accaatgacg gtaattggat gggccattga acttcaacgt gagacactat
     3121 gctctccacc ccctagaggt taatccaaag cacgttttgg cccgattgca cacaacgagg
     3181 cttatctatc tctcaataga taccgactcg catggaaaag ttgatgtcgc gtcgatcata
     3241 tgtaccttgt aagtttgctc ttgcctattc gagtacgagt tcgaaggatc aaagaacagc
     3301 acacagcgcc attaaatgag agttatgcca agaatatcca ctaagtgtcg ccatctcctg
     3361 cggggaaagt aaaaactgga tttcgcccgt ttataggaga cattgaaagt tactaatttc
     3421 acttgcaagc cgtggcagtt tagtgcattt cgctctcgca aacgggctgc gccaatgaga
     3481 aacaaccgcg tcaatgcatc gtggagtact tttttccact ctatctggcc tagctacaac
     3541 cggcagcctc cggagggatc tttgtgaaac ggccgatgcc ttggcccgcg cttgtatgtt
     3601 ccaatttggt gagttgcagc tgggcgggaa aggtggatat gttggagatg agtgagttcg
     3661 ggaagattcc cggacgagcc tagatggagt acggagtaca tacttatgca gctatacagg
     3721 atcttcctcg ggttttccta tccgagctgc cgccgctttt atgggctccc gaggtcgtgg
     3781 gagatcacag gacagataag tacgggctcg gaaaggaaag tcggtcacgt gtaaattgag
     3841 cgatgcttag tggctacaaa ctatacccaa aatggatcag agagctacat tccagacatg
     3901 taggaggagt atctagatac acgccagaat tatcattcct gttgcaatca ctagtttaga
     3961 acttttggct gggagtagac ctcgtgtgca gcctatgaag acctagtctg tgtaggaatg
     4021 aagtgcacta gtcatttcta ttcttcctta tcttcccctc cttggttagt aggggcctcg
     4081 tactaacagt agcctaagtc acatggccgg taaatagctg cgagactagt gatgcacact
     4141 gtgcgatccc gtagccagat ggagtacata gagaagggat atgggattgg ctggacttga
     4201 cgcccgatga aaacgagtca gaaataatcg actcaatttc tttggtccta tcgcttgtgt
     4261 ttttgtttta ggaaataccg ctatatagag ggctcttgat gatcttaact aaatttgtag
     4321 attcgacggc aatgcatcct tgccctgtgc acaacagcag tcttcgctga tatatatata
     4381 tatatatata tttccaatac ttagcctccg acctgtcttc tgttcaaaca aggccactcc
     4441 aaatcaactt ccatccactg actacacaga gacatctacc tatcttccac ttgaggcatc
     4501 tgtaacagtg aaaggagatc tagcatgccg gaagtagatc cctgttcctt ggacaccgca
     4561 caaccatcga tggtcaccaa atcggtagtc cttccaaact cggaagcaga aagtcatacc
     4621 tcattaaatt gagcgctggg tcttccaaat tgcaaaagtc cacaagttaa tgaggataca
     4681 aaataaggtt atgactatag tcgctctgac ggcccgtgca tagttacgtc agcagatacc
     4741 tgcggcgtgc tcatatttac ccggaggtca aaaagcggca agatatatgg cctaaagtag
     4801 aagggggaag gtttccccga agttgacccc agtaccaggc ggcacacaca gcctacttga
     4861 gtgtaactag tttgcatcta cactttttgt ataaatgaga acatcccggt cttacaacat
     4921 gtatcccagt atcagcccgg tgctaatcgt taccagtccg atatgcttgt gcacacgtgg
     4981 tcacctcgac actaaccaga catgtccagg aacctgacag caacttccaa agtggaattg
     5041 aagctcctat tcagcaactt gcaatgttcc aggcagttcc agaaatatat taatggtctt
     5101 catatggaat cccccgggac acacccctgt aactacggat acccacagag cggtggcgca
     5161 agccgttcga atccttgcag gaaagtagcg ccggagcaca ttgacctagc atccgaacaa
     5221 agttaccatt ccgtggctgg acttcaagtg ggggtcttga aggatgccac gtagcaatca
     5281 ttagctttcc tacggagtat tccgtcctcg gtatccaatc ccagctagag caattgataa
     5341 acattctcaa ttgggattta tacatgaaca taaccccttg cggtaggcaa gttgtctctt
     5401 aaacttcgga cgctgaattt tcagcatcaa acacctcacc accatgctac tactatggtt
     5461 tgggttcttt tcctttgttt gtgggttggt gatttaccgg ctacaatttc accctcttag
     5521 caagtttccg gggccgaaac tagctgccct aacaagtctt tatgaatttt attacaatgt
     5581 agtcctgggt ggccggtatt tgtgggagat agagagaatg cacgagcaat atggtaagga
     5641 accattattc gagaccttgg gtcatactaa acaattaggt cctattgtgc gcattactcc
     5701 tcacgagctt catgtggcag atccaaactt ctatacggag atatatgcag gccctaccag
     5761 gaggcgtgac aaagatccaa gacttgtacg gctagcaggt caaccgactt ccatgttcgc
     5821 gactgttgat catggcctgc acagttcgcg tcgagctatc ctgaacaact atttctctaa
     5881 aaggtcaatt gcaggcctag aagacatgat tcagggcaaa gtgcaaaagc tcgttaaacg
     5941 gctaaacatt gcctgtgatc agggcactgt tgtacagctg gatgctgcat catcggcttt
     6001 gactgcggac attatctcag agtacgcgca tggtgtaagc cttgactact tggacgacgt
     6061 caatttcaat aacgaagtcg cagactcaat cttgagtctt gcatctgtag ttcatgtgtt
     6121 gaaatttttc cctttccttt tggatctgtc aaagttcata cctgataagg tgcttgagaa
     6181 cctttggtcc cacgcagcaa acatattgcg actgcagaaa ctggttcgtg ctcaagcaga
     6241 tgtcgcactc caaaacggag gtaaagtgaa cggtcaagca acaatgttcg gtgctctctg
     6301 tgacccatcc ttgcctgcgc aagaaagaac actggatcgg ttgcaggacg agggattttc
     6361 gttgattggt ggaggtacag agactacaac agggacattg aaggtcatca tgttccactt
     6421 gctcaatgag aaggctttac tccgcaagct ccgcaaagag cttgaagaat ctccatctgg
     6481 cacctgggcc gaacttgaaa aactacccta catggtgagc aatgcaatat gccatacata
     6541 aagacaagac taacccatca acttcgttcc agagaggagt gatgaatgag ggactccggc
     6601 tctccggcgt cataactcgt cttccccggc gtgctcccga tgaagcactg agatacaagc
     6661 agtggacaat tccaccaaac gtaagttcct atattctccg agatcgacaa cgctaacgca
     6721 accttgccct caacagtccc taatgagtac atcctcccat tttgttcata caaattcaga
     6781 cttgttccct gatccacttg tctttgaccc cgagcgctgg atccgagctg aagcggccgg
     6841 ccagcgcctg gagcacatga ttgtcacctt cagcaagggt tccaggcaat gcatgggcaa
     6901 ccagtaagat aatattcagc ttcctctcct gggttctcac ttaccctgga atttagtttg
     6961 gctttggcgg agttgtacct ggtcatttcc actctggtgc gtgaattcga tatggatcta
     7021 tatggagtga cggccgacaa tatcgtcaca catagggagt atggctttgg agtgccaaaa
     7081 gagagaggtg ggggactcag agtaagtatt tcacgggttc gtaccccgta gtttgcatta
     7141 ttt
//
