BGC0002324: myxochelin B biosynthetic gene cluster from Archangium violaceum
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Location: 8,359,747 - 8,377,243 nt. (total: 17,497 nt).
This entry is originally from NCBI GenBank CP069338.1, but has been modified (see Modifications tab for details).

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
Modifications
General information about the BGC
MIBiG accession BGC0002324
Short description myxochelin B biosynthetic gene cluster from Archangium violaceum
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
  • PKS (Unknown)
Loci
CP069338.1
8359747 - 8377243
via
Compounds
  • myxochelin B
  • myxochelin N
  • myxochelin O
  • myxochelin P
  • myxochelin Q
  • myxochelin A
Species Archangium violaceum [taxonomy]
References
Chemical products information
myxochelin B Evidence:
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Chemical database entries
NPAtlas
myxochelin N Evidence:
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Chemical database entries
NPAtlas
myxochelin O Evidence:
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Chemical database entries
NPAtlas
myxochelin P Evidence:
(no structure information available)
myxochelin Q Evidence:
(no structure information available)
myxochelin A Evidence:
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Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • JQX13_35800
  • QRK05497.1
 8359747 - 8360520 (+) 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
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    • JQX13_35805
    • QRK05498.1
    • dhbC
    		 8360616 - 8361842 (+) isochorismate synthase DhbC
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      • JQX13_35810
      • QRK05499.1
      		 8361839 - 8363491 (+) (2,3-dihydroxybenzoyl)adenylate synthase
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        • JQX13_35815
        • QRK05500.1
        		 8363506 - 8364417 (+) isochorismatase family protein
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          • JQX13_35820
          • QRK05501.1
          • mxcG
          		 8364482 - 8368804 (+) myxochelin non-ribosomal peptide synthetase MxcG
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            • JQX13_35825
            • QRK13959.1
            		 8368842 - 8370221 (+) 3-deoxy-7-phosphoheptulonate synthase class II
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              • JQX13_35830
              • QRK05502.1
              • mxcH
              		 8370281 - 8372818 (+) TonB-dependent siderophore myxochelin receptor MxcH
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                • JQX13_35835
                • QRK05503.1
                		 8372871 - 8374109 (+) hypothetical protein
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                  • JQX13_35840
                  • QRK05504.1
                  		 8374119 - 8375219 (+) PepSY domain-containing protein
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                    • JQX13_35845
                    • QRK05505.1
                    		 8375234 - 8375983 (+) MotA/TolQ/ExbB proton channel family protein
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                      • JQX13_35850
                      • QRK05506.1
                      		 8375986 - 8376414 (+) biopolymer transporter ExbD
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                        • JQX13_35855
                        • QRK05507.1
                        		 8376401 - 8377243 (+) TonB family protein
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                          Biosynthesis information

                          Biosynthetic modules

                          Name
                          Unk01
                          Type
                          nrps-type1
                          Genes
                          JQX13_35810
                          Substrates
                          nicotinic acid, benzoic acid (evidence: Structure-based inference, Feeding study)
                          Integrated Monomers
                          Domains
                          adenylation
                          Name
                          Unk02
                          Type
                          nrps-type1
                          Genes
                          mxcG
                          Substrates
                          lysine (evidence: Structure-based inference [2])
                          Integrated Monomers
                          Domains
                          adenylation
                          Annotation changelog

                          Entry version: 2

                          Date
                          Changes
                          Submitters
                          Reviewers
                          2022-10-07
                          Added chemical structures for compounds: myxochelin N, myxochelin O, myxochelin B.
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          2022-10-07
                          Added NPAtlas links to compounds: myxochelin N, myxochelin O, myxochelin B.
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                          Entry version: 1

                          Date
                          Changes
                          Submitters
                          Reviewers
                          2022-09-15
                          Entry added
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          2022-09-15
                          Added NRP substrate specificities
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          Detailed domain annotation
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                          Modifications to original record
                          • JQX13_00005 crossed the origin and was split into two features