BGC0002329: trinickiabactin biosynthetic gene cluster from Trinickia caryophylli
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Location: 916,962 - 989,289 nt. (total: 72,328 nt).
This entry is originally from NCBI GenBank VJZF01000001.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
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General
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Biosynthesis
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NRPS/PKS domains
General information about the BGC

MIBiG accession | BGC0002329
Short description | trinickiabactin biosynthetic gene cluster from Trinickia caryophylli
Status | Quality: questionable The quality level of this entry. Status: active The status of this entry. Completeness: unknown Whether the entry covers everything needed for the pathway producing the compound(s)

Biosynthetic class(es)

- NRPS (Type I)

Loci
VJZF01000001.1
930564 - 971769
via
Compounds

- trinickiabactin

Species Trinickia caryophylli [taxonomy]
References

- [1] Structure elucidation and biosynthetic locus of trinickiabactin from the plant pathogenic bacterium Trinickia caryophylli. Jiao J et al., J Antibiot (Tokyo) (2020) PMID:31605027

Chemical products information
trinickiabactin Evidence:
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Chemical database entries
NPAtlas
List of genes involved in compound(s) production

Identifiers | Position | Product | Functions | Evidence | Extra
--- | --- | --- | --- | --- | ---
FNF07_04250 | 930125 - 931478 (+) | MFS transporter |  |  | copy AA seq copy Nt seq
FNF07_04255 TRX17522.1 fhuB | 931577 - 933571 (-) | Fe(3+)-hydroxamate ABC transporter permease FhuB |  |  | copy AA seq copy Nt seq
FNF07_04260 TRX20192.1 | 933568 - 934545 (-) | ABC transporter substrate-binding protein |  |  | copy AA seq copy Nt seq
FNF07_04265 TRX20193.1 | 934608 - 936752 (-) | TonB-dependent siderophore receptor |  |  | copy AA seq copy Nt seq
FNF07_04270 TRX17523.1 | 936962 - 942673 (-) | non-ribosomal peptide synthetase |  |  | copy AA seq copy Nt seq
FNF07_04275 TRX17524.1 | 942732 - 958793 (-) | amino acid adenylation domain-containing protein |  |  | copy AA seq copy Nt seq
FNF07_04280 | 958909 - 959247 (-) | amino acid adenylation domain-containing protein |  |  | copy AA seq copy Nt seq
FNF07_04285 TRX17525.1 | 959260 - 962799 (-) | AMP-binding protein |  |  | copy AA seq copy Nt seq
FNF07_04290 | 963036 - 963855 (-) | ATP-binding cassette domain-containing protein |  |  | copy AA seq copy Nt seq
FNF07_04295 TRX17526.1 | 963852 - 965531 (-) | cyclic peptide export ABC transporter |  |  | copy AA seq copy Nt seq
FNF07_04300 TRX20194.1 | 965634 - 966605 (-) | YqcI/YcgG family protein |  |  | copy AA seq copy Nt seq
FNF07_04305 TRX17527.1 | 966763 - 968199 (-) | peptide synthetase |  |  | copy AA seq copy Nt seq
FNF07_04310 TRX17528.1 | 968270 - 969289 (-) | TauD/TfdA family dioxygenase |  |  | copy AA seq copy Nt seq
FNF07_04315 TRX17529.1 | 969286 - 970107 (-) | thioesterase |  |  | copy AA seq copy Nt seq
FNF07_04320 TRX17530.1 | 970111 - 970353 (-) | MbtH family NRPS accessory protein |  |  | copy AA seq copy Nt seq
FNF07_04325 TRX17531.1 fdhA | 970570 - 971769 (-) | formaldehyde dehydrogenase, glutathione-independent |  |  | copy AA seq copy Nt seq

Biosynthesis information

#### Biosynthetic modules

Name
Unk01
Type
nrps-type1
Genes
FNF07_04275
Substrates
3R-hydroxyaspartic acid (evidence: Structure-based inference [1])
Integrated Monomers
Domains
adenylation
Name
Unk02
Type
nrps-type1
Genes
FNF07_04275
Substrates
threonine (evidence: Structure-based inference [1])
Integrated Monomers
Domains
adenylation
Name
Unk03
Type
nrps-type1
Genes
FNF07_04275
Substrates
threonine (evidence: Structure-based inference [1])
Integrated Monomers
Domains
adenylation
Name
Unk04
Type
nrps-type1
Genes
FNF07_04275
Substrates
N5-nitroso-N5-hydroxyornithine (evidence: Structure-based inference [1])
Integrated Monomers
Domains
adenylation
Name
Unk05
Type
nrps-type1
Genes
FNF07_04275
Substrates
glycine (evidence: Structure-based inference [1])
Integrated Monomers
Domains
adenylation
Name
Unk06
Type
nrps-type1
Genes
FNF07_04270
Substrates
N5-nitroso-N5-hydroxyornithine (evidence: Structure-based inference [1])
Integrated Monomers
Domains
adenylation
Annotation changelog

#### Entry version: 1

Date
Changes
Submitters
Reviewers
2022-09-15
Entry added

- (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

- (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

2022-09-15
Added NRP substrate specificities

- (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

- (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

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