LOCUS       BGC0002330             16516 bp    DNA     linear   BCT 20-APR-2020
DEFINITION  Kamptonema sp. PCC 6506 landornamide biosynthetic gene cluster,
            complete sequence.
ACCESSION   BGC0002330
VERSION     BGC0002330
KEYWORDS    .
SOURCE      Kamptonema sp. PCC 6506 (Oscillatoria sp. PCC 9029 = Lyngbya
            kuetzingii UTEX B 1547)
  ORGANISM  Kamptonema sp. PCC 6506
            Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
            Oscillatoriales; Microcoleaceae; Kamptonema.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 17:20:22
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16516
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..699)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GST_N_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GST_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1193:glutathione S-transferase (Score: 207.1; E-value:
                     3.5e-63)"
                     /gene_kind="biosynthetic-additional"
                     /product="glutathione S-transferase-like protein"
                     /protein_id="QIZ86013.1"
                     /sec_met_domain="GST_N_3 (E-value: 9.4e-12, bitscore: 34.6,
                     seeds: 52, tool: rule-based-clusters)"
                     /sec_met_domain="GST_C (E-value: 7.2e-12, bitscore: 34.8,
                     seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIEVYYWTTPNGHKITMFLEEVGVPYTLIPINIGAGDQFKPEFLK
                     IAPNNRIPAIVDREPVDGGEPISVFESGAILLYLAEKTGKLIPGEIRDRLEVLQWLFWQ
                     MGGLGPMAGQNHHFSQYAPEKIPYAIARYVNETGRLYAVLNRRLSDREFVGGDYSIADI
                     AIYPWIVPYALQGQKLEDFEHLQRWFEAIKARPATIRAYQQAEAFKTQAISIEESRNLL
                     FNQSAKTVND"
     source          1..16516
                     /collected_by="E.G. Pringsheim"
                     /culture_collection="PCC:9624"
                     /db_xref="taxon:272129"
                     /isolation_source="fresh water"
                     /mol_type="genomic DNA"
                     /note="Oscillatoria sp. PCC 9029 =3D Lyngbya kuetzingii
                     UTEX B 1547 = [Oscillatoria] sp. PCC 6506"
                     /organism="Kamptonema sp. PCC 6506"
                     /strain="PCC 9029"
     misc_feature    1..16516
                     /note="landornamide biosynthetic gene cluster"
     protocluster    1..16516
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[8859:12132]"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      8860..12132
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     protocluster    1..16516
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[7353:12559]"
                     /cutoff="20000"
                     /detection_rule="(PoyD or TIGR03793)"
                     /neighbourhood="10000"
                     /product="proteusin"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      7354..12559
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PoyD or TIGR03793)"
                     /neighbourhood="10000"
                     /product="proteusin"
                     /protocluster_number="2"
     cand_cluster    1..16516
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(PoyD or TIGR03793)"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="interleaved"
                     /product="proteusin"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="2"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..16516
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0002330"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..16516
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="proteusin"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="(PoyD or TIGR03793)"
                     /rules="cds(LANC_like and DUF4135)"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            990..2039
                     /gene="OspT1"
     CDS             990..2039
                     /codon_start=1
                     /gene="OspT1"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1133:Transcription regulator, crp (Score: 50.6;
                     E-value: 2.5e-15)"
                     /gene_kind="regulatory"
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /protein_id="QIZ86014.1"
                     /transl_table=11
                     /translation="MLFMKTPQIVPETLAQFPFFSILNQRDLEWILHEGTPEKCQPGRV
                     LIQEGHPVESLYLSISGTLAVTVSRQDGGEQELKRLFAGELMGEMSFLDNHLPSATIKV
                     VEDSQVLSLSKTTLVRKLETDGDFASRFYHLLSLKLSDQLRGLSGLLTENQALPSEPLR
                     KVLLVFAVLNDSDIAWMIAHGVPEKVIPNTVLIQQGKPVPAVYILLEGTLGIYISLTKN
                     GITTEKEVAKSIKGEILGEMSFVEIGTASATVKVVENAWLLALPQSQLAAKLEEDRAFA
                     SRFYRAIAVVLSNRWRDRLMRRGFATLANDLTSMLSEEIDAEDELDFDVLEGTAIAGTR
                     FDWMIRQLR"
     gene            2063..3883
                     /gene="OspT2"
     CDS             2063..3883
                     /codon_start=1
                     /gene="OspT2"
                     /product="NHLP bacteriocin system secretion protein"
                     /protein_id="QIZ86015.1"
                     /transl_table=11
                     /translation="MFTKDSKKRNIFRQESLERLSSPERLDQLMQVVGPKEWVPLSVLG
                     GLVIVGLAWSIFGKIPITIDGRGIFIAPRQVVDFQSPISGQLKTLYVQAGQCIAKNERL
                     ATIDPSELKQRLKLAQDKQAQLQQQSNETSLLLNQGTRSEQDAIIASKISLQQRLLAAQ
                     SMTPMLQNKGLDAIAQQRQSLQQRLQDLQQMTPLIQSKGLDAIVRQRQSIQQQLRDTKS
                     LTPTLKEKGLNTITEQRQSLQQRLENAKKLAPVLAERLEKRRQLFSEGAIPQDTLLEAE
                     QEYFQKLESVAELKAELKDLDAREVEAQQQYLENLNQIGALQAKLKDIDVQEATTQQQY
                     LNSLNQINEIQAQLKDLEVKETESQQRHLENLNQIRQTQADLQELETKAKRLEQDNLEQ
                     LNNKQNPIQDVRREIAQLQQQIIDNSEIRSPHAGCILEIMATEGQVVSPGTNLGSLNVT
                     SRKGTIVGVSYFTVKDGKKVKPGMMIQITPDTVKRQRYGGIVGTVTSVSEFPITQKGVA
                     AVIGNPDLVSGLIQNVSGGAGGENAGGAIVEVRAQLESDQTPSGYKWSSSQGPQLKITP
                     GITTTARVRVEEQAPITFLLPVLREWTGVY"
     gene            3883..6120
                     /gene="OspT3"
     CDS             3883..6120
                     /codon_start=1
                     /gene="OspT3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 274.1; E-value: 4e-83)"
                     /gene_kind="transport"
                     /product="NHLP family bacteriocin export ABC transporter"
                     /protein_id="QIZ86016.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 8.2e-40, bitscore:
                     125.0, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKMLKMGFSKSKQPKIFKRVKTPTLLQMEAVECGAAALGIILRY
                     YGRIVPLPELRTNCGVSRDGSKASNVLKAAKNYGMQAKGFKKQLAQLQEIQPPFIVFWN
                     FNHFLVVEGFTKDRVYLNDPGTGPRSVSFEEFDQAYTGVVLLMEPGPEFKRGGRKPSII
                     RSLMERLKGSVGAIIYCILAGFFLVIPGLAISIFGQIFVDNILVENRYDWLRPLLIGIG
                     ITALIQASLTLLQLRYLRHLQIKLSVGMSSRFLWHILRLPVGFYAQRFAGEISNRAQLN
                     TRVADVLSGQLAQTAIDVVMVIFYAAVMFAYDWVLTIISIFLAILNVSTLQWVAEKRKD
                     SHMRLVQDQGKAAGVAIAGLQSIETIKSAALESDFFARWAGYYTKAENAQQELGISNQA
                     ITVLPNFITALTTLSLLIIGGLRVMDGHLSIGMLVAFQSLMALFQKPVNTLVSFGSTLQ
                     ELEGDINQLDDVLDNEVDSQINLENPQNPFQVDAIPRTNGKLTNSAFKLAGYLELRNLT
                     FGYSRIDAPLVENLSLSLRPGQRVALVGGSGSGKSTVAKTVAGLYEAWSGEILFDGIPR
                     HKIPRSVLTNSLSMVEQDIFLFGGTVRENLTLWDSTIPKDQLLRACQDAAILDVVLAIS
                     GGIEGNLLEGAANLSGGQRQRLEIARALVNDPSILIMDEATSALDAETEKIIDQNLRRR
                     GCTCLIVAHRLSTIRDCDEIILLDRGKVVQRGTHEEMRAVPGPYMRLIQSE"
     gene            complement(6302..7228)
                     /gene="OspR"
     CDS             complement(6302..7228)
                     /codon_start=1
                     /gene="OspR"
                     /product="peptide arginase"
                     /protein_id="QIZ86017.1"
                     /transl_table=11
                     /translation="MAKIPFYIMEEHNEAFFIWHYAVAEGWINKNQNTLLHVDEHSDLV
                     VPILNSSLKSVNENIKRVHDFTYSELTIANFIYPALYQGVFSQVYWLRQKHDPKLNGQK
                     QLNIYSHQGEGKRLILKSKVDFNNLFNPDCKSFTITPLNAQDDLSSEESKKLNKSVILD
                     IDIDYFSCDNVSGEYLEVEITEEAYYDYINNLYNKLRICWGGNASVKYMDGKYYFCIIQ
                     PDKLVAENLKVSEDAIVERIDALIDFLKVNEIQPKLIDVCRSRLSGYTPNDQWEFIENT
                     LVEKLSSIYEFEPIFVSELSKKVLVEV"
     gene            complement(7354..8802)
                     /gene="OspD"
     CDS             complement(7354..8802)
                     /codon_start=1
                     /gene="OspD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     proteusin: PoyD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Proteusin_Epimerase_RRE"
                     /gene_kind="biosynthetic"
                     /product="rSAM peptide epimerase"
                     /protein_id="QIZ86018.1"
                     /sec_met_domain="PoyD (E-value: 7.4e-248, bitscore: 811.9,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="Proteusin_Epimerase_RRE (E-value: 2e-27,
                     bitscore: 84.5, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAKTLPLAPQLAQLDDALEQKTIERWMKLDEQELTSISHIKRFT
                     EYYEADPEFRKNVAIAPEQTVAQYNLKIPLAEIRWLWDAEFVKSQQSQDIPFPIALQRF
                     IDYEKARERYFFRWRNNMPDSDPRFQAWRDRQIARGDSEIRKSHNAQILHAPVAFELTK
                     GCSVGCSFCGISAPRFSDIFTYTAENAQLWGEVLEVIKEICGPAAGTGFCYWATDPLDN
                     PDYEQFVSDFQAILGAIPQMTTAQPMKYPARVRSLLKFSDSQGFTYHRFSILSLKILQN
                     VYAEFSPEDLIRVGLVMQNKESLMNKAVAGRSWEKQNKAGEASDELAQSTIACVTGFLF
                     NMVERSVKIISPCKADDRWPNGYRVYDRGNFESANDLKVLLERMITQQMPLEIRADQNL
                     RFRRDLKHENLDDGFKLSTRFLTLKFRHRPLIKELGEAILKGNKTAAEIVAEFEKLGVN
                     ATETYYSLNLMFNRGVLDDEPQPG"
     gene            complement(8860..12132)
                     /gene="OspM"
     CDS             complement(8860..12132)
                     /codon_start=1
                     /gene="OspM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070:lanthionine synthetase C family protein (Score:
                     958.7; E-value: 6e-290)"
                     /gene_kind="biosynthetic"
                     /product="type 2 lanthionine synthetase"
                     /protein_id="QIZ86019.1"
                     /sec_met_domain="DUF4135 (E-value: 4.5e-104, bitscore:
                     337.7, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.6e-69, bitscore:
                     223.5, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQVCKKDLIKIVEKASTIDERLNSNFAFDSASESPDIINARIKQW
                     CQVVAEGDFAKFQQHLSQMGLDLNSARNAVSNVRFQGDRLPAWAQTLEESLQARTAIAK
                     DNLAFLNPLRPLPFEEIWLSSVYIAREKLIANTGNSYSLLTAAAHANLERSLLELLANL
                     GSRALFQKFKIFQQQKQPALVSSWPLTVTYTNKQYKQFIEDLLNGELITFFQEYSVLAR
                     LAGTLVNLWVETTTEFLQRLASDWSEIQQTFQPETELGQVTVIQPNLSDRHRQGRSAIA
                     ILFSSGLELVYKPKSLGTEKAYSQLLTWLNNRDIPLTFKPQKIIDRSTYGWAEFIEHLP
                     CQNQAQASRYYQRMGMFLCLAYVLKGTDFLDENIIACGEYPVPIDLEMLLNHGVRGEVS
                     TADRDAYSLAYEQMYSSVLDTGLLPRWLFVATGQSLDVSGLGSGSQQETLFKVTKWQNV
                     NKDDMVLGSDYEAMPPGKNIPYLNGVGLSPSNYLEELIAGFRQMYQFLREQRDALLTAD
                     SPLMNLGKQQVRFTFRATKIYCVILEMSLKLEALKDGANRSIQLDYLSRERFWNDKFHS
                     LRRNSEGAVGQLIAAEKQALEYMDIPLFTAWANQDALPIATNETIENCFAQPSIDLAIA
                     RLQQLSADDLKWQIGLIRGSLYAQIAKQCESSSLSPSLELQLDLVPQLDSKDLVREAEA
                     IAKRLQNNALHSPNGSASWIALVYLMEIQRFQLEPVSDRLYDGSCGIGIFLSALAKIQG
                     NSELQELTLAAIESLRQHLQNPQISRAMVQKIGIGGAVGCGSIIYGLTRIGQFLENSAV
                     IEDATKAAALLTPEKFADDRKFDVTFGTAGAILGLLALYEVTKEPAILEQAIAGGKHLL
                     QYRTASDSGFRTWQTVDGKLLTGFSHGAAGIAYALLRLYKVSNEVVFLEAAAEAIAYER
                     SVFSPKAGNWPDFRNSVSRNGEPSFTNTWCHGAPGIGLARLGSLEMLNSAEIQQDIEFA
                     IAATPQVKAEEIDNYCCGNFGRLELFLEAGKRLNRPELITIAQQQAAWVVTRARQTGSF
                     QVFANVAGDTYSPGLFTGTAGIGYQLLRLAYPDLLPSLLLWK"
     gene            complement(12263..12559)
                     /gene="OspA"
     CDS             complement(12263..12559)
                     /codon_start=1
                     /gene="OspA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     proteusin: TIGR03793"
                     /gene_kind="biosynthetic"
                     /product="proteusin family (NHLP leader peptide) precursor"
                     /protein_id="QIZ86020.1"
                     /sec_met_domain="TIGR03793 (E-value: 1.4e-27, bitscore:
                     84.7, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTRKEAEEQLAIKALKDPSFREKLKANPKAVISSEFNTQVPDDL
                     TIEVVEETATKMYLVLPAPEAVEEELSEEQLEAVAGGGCWIAGSRGCGFVTRT"
     CDS             12806..16516
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1173:WD-40
                     repeat-containing protein (Score: 362.7; E-value:
                     4.5e-110)"
                     /gene_kind="other"
                     /product="WD40 domain P-loop ATPase domain"
                     /protein_id="QIZ86021.1"
                     /transl_table=11
                     /translation="MNVSQALELADNLVVAKTARHLSDLQRLLLEEFWTRPSLRYDEVA
                     QTHGYSASYLKQDAGPKLWRSLSDACGEKVSKANFRAALERKWSAVGEKRNLSLPENSD
                     NYPVSVVQQDPSTSSLAVLAPPTSYPTQDLLSSPVVPPDDNLPPAQLQSYQDWGIAPDV
                     STFYDRYEEIAQLKQWIVGDRCRLVAIVGLGGIGKTYLSVKLAEQIQDCFQYVIWRSLR
                     NAPPLQQILTSILQSIANSQEIDLAATVHEKISCAIDFFRNHRCLLILDNVETILQGGV
                     YTGYYQEGYEDYGEFFKCLGEGRHHSCLLLTTREKPKEISIMQGETLPIRCLRLQGLST
                     SAGLQLLRLKGCYWTSEQEGFALVEQYAGHPLALKIIASTIRELFEGNISEFTQHNLLV
                     IDEIRTLLEEQFNRLTDLGKALFYWIAINLEPVSAEELYSDIYPLVSKPRLVETLKSLV
                     QRSLIEQTGSQFVLQPVVREYAIGSLVKQVCEEIETGNFAILNSHALLKAQAKDYIRQT
                     QIKFILNPILERLLTAFKTKARIANHFKQLIHELQMQPSQSPGYAAGNLLNILCQMQID
                     VSGYDFSHLTVWQAYLQGTNLHDVNFKGADLAKSVFAKQLTNVLALAFSPDGTLLATGD
                     ANGEICLWLADDGTLLRIYEGHAGWVNSIAFSPNGSLLCSGSSDRTVKIWDVGTGNCLK
                     TLSGHNQRVRTVAFSPDSQTVASSSSDRTVRLWDIQSGWCQQIYAGHTSYVWSVTFSPN
                     GRTLASGSEDRTIKLWDVLTGKCLQTWQDSSSWVRTLAFSPDGKTLASGGGDRTVKLWE
                     TSTGTLLASLPGHSQRLRSLAFSPDGKLLASGSGDRTVKIWDLTAKRCLKTLHGHSSRL
                     CAVVFSPDGNTLVSGGEDRTVRFWEVSTGNCNSIWQGYASWFQSVAFSPDGKTLASGSE
                     DGTVKLWKTNLNSSGPCSPITLLGHAGWVCSVAFSPDGTTLASASSDYTIKLWDASSGT
                     CLKTLLGNPRWIRSIAFSPDGKMLASGGGDNTVKLWNLRSGNCCATWRSHAGWLWSVAF
                     SPNGAIVASASEDKTVKLWCVHTGRCLRTFEGHSSWVQAVAFSPDGRLLASGSCDQTIK
                     LWDIDTGQCLQTFWDHVSWVQTVAFSPDGKFLASGSCDQTVKFWEIDSGECWQTLSAHT
                     NWVWAIAFSPNGDILASAGQDETIKLWKVSTGECLETLRSKRLYEGMCLRESTHLTEAQ
                     LATLKLLGAFV"
ORIGIN
        1 tcaatcatta actgttttgg cagactgatt aaacaacaaa tttcgcgact cttcaatact
       61 aattgcctga gttttgaaag cttctgcttg ctgataggct cgaatggttg cgggacgggc
      121 tttaatcgct tcaaaccaac gctgcaaatg ctcaaaatct tctagttttt gaccttggag
      181 cgcatagggt acaatccagg gataaatggc aatatcggcg atcgaatagt caccgccaac
      241 aaattcgcga tcgcttaacc gccgattcaa tacagcatac aaacgtcccg tctcattcac
      301 gtaacgtgcg atcgcgtagg gaattttttc gggagcatac tgactgaaat gatggttctg
      361 tccggccatt ggcccgagac cgcccatctg ccagaatagc cattgtagaa cttcgaggcg
      421 atcgcgaatc tcgccaggga tcaacttccc agttttttct gccaaataaa gcaaaatcgc
      481 ccccgactca aacacagaaa ttggttcgcc accatccaca ggttcgcgat cgacaatagc
      541 aggaatgcga ttgttagggg caatcttcaa aaactccggt ttaaactgat cgcctgcacc
      601 aatattaatc ggaatcagcg tataaggtac tccgacttcc tccagaaaca tcgtaatttt
      661 atgtccgttg ggcgttgtcc agtaataaac ttcaatcatt cctgtctcct gagattacaa
      721 aaattgtgct tgggatatta cccgagctca aattatagct taacaaagct taatataaca
      781 gttgagtaat taaaactcaa ccagcctgcg ggtgtaaatt tttaataagc ttcttgacat
      841 tagaattttt tttttgtatt atttgctcag tgaaaatgta caaaataagt ttgatagcaa
      901 aactcaaact cccatccaaa ttccaattct agggtgcttt ctatctagtt ttcccaagtt
      961 tagcttatcc tcgcagaatt agctttacaa tgttatttat gaaaactccg cagatcgtcc
     1021 cagaaactct ggctcaattt ccctttttta gtattttaaa tcagagggat ttagaatgga
     1081 ttttacatga aggcacccct gaaaaatgtc aaccgggtcg agtgctgatc caagaaggtc
     1141 atccagtaga atcactctat ctatctatct caggaaccct agctgttacc gtatcgcgcc
     1201 aagacggagg agaacaagaa ctcaagcgac tattcgccgg cgaactaatg ggagaaatgt
     1261 cttttttgga taatcattta ccttctgcta ccatcaaggt agtcgaagat tctcaggtat
     1321 tgtcactatc caaaaccacg ctggtccgca aactagaaac agatggagat tttgcctctc
     1381 gtttctatca tttattatcc ttaaaactct cggatcaatt gcgcggctta tcaggtttac
     1441 taacggaaaa tcaagcatta cccagcgaac cattacgaaa agttctactt gtatttgccg
     1501 ttctcaatga tagcgacatt gcttggatga ttgctcacgg agtacccgaa aaagttattc
     1561 ctaatactgt tctcatccaa caaggaaaac ccgtacctgc cgtttacatt ttactagaag
     1621 gcacattagg tatttatatt tcccttacca aaaacggaat cacaacagag aaagaagtcg
     1681 caaagtcaat taaaggcgaa atcctcggtg aaatgtcttt tgtagaaata ggcaccgcct
     1741 cagctactgt caaagtagta gaaaatgctt ggttactagc tctacctcaa tcacaattag
     1801 ccgccaaact agaggaagac agagcctttg caagtagatt ttatcgagcc attgctgttg
     1861 tcctatcaaa tcgttggcgc gatcgactta tgcgtcgtgg atttgccact ctcgccaacg
     1921 atcttacttc catgctctcc gaagaaattg atgccgaaga cgagcttgat tttgatgttt
     1981 tagaaggaac tgccattgcc ggcacccgct ttgattggat gattcgccag ctacgttaac
     2041 cgttataatt gagtaacata cgatgtttac taaagatagc aaaaaacgaa atatttttcg
     2101 ccaagaatct ctagagcgac tctcttctcc agaacgcctc gatcaactca tgcaagtagt
     2161 tggccccaaa gaatgggtac ctttaagcgt tttaggaggt ttagttatag tcgggttagc
     2221 atggagtatc tttggcaaaa taccaatcac cattgatgga cgcggtattt ttattgcacc
     2281 ccgtcaagta gttgattttc aatccccaat ttcagggcaa ctcaaaacat tatacgttca
     2341 agccggccaa tgtattgcta aaaatgaacg cttagcaacc atcgatccct ctgaactaaa
     2401 gcagcggcta aaacttgctc aagataaaca agcacaattg caacagcaat ctaacgaaac
     2461 atctttgctc ttaaatcagg gaactcgttc tgaacaagat gccattattg cttccaaaat
     2521 tagtcttcag caacgtcttt tagccgctca gtctatgact cctatgctgc aaaataaagg
     2581 cttagatgct attgcccaac aacgtcagag tctacaacaa aggttacagg atttgcaaca
     2641 aatgacacct ctaatccaaa gcaaaggttt agatgccatt gtcagacaaa gacaaagtat
     2701 tcaacagcaa ctacgggata ctaaatcact cactcctacc ctcaaagaaa aaggcttaaa
     2761 taccattact gaacagcgtc agagcctgca acaacgctta gaaaatgcta aaaaactagc
     2821 gccagtttta gcagaaagat tagaaaaacg tcggcaactc ttctcagaag gtgccatccc
     2881 tcaagatact ctcctcgaag cagaacaaga atattttcag aaattagaaa gcgttgcaga
     2941 actcaaggca gaattaaaag atttagatgc tcgtgaagtg gaagcacaac agcaatatct
     3001 ggaaaatctc aatcagattg gagcgcttca ggcaaaactc aaagatatcg atgttcaaga
     3061 agccacaacc caacaacaat atctcaatag tctcaatcaa atcaatgaaa ttcaagcaca
     3121 acttaaggac ttggaagtca aggaaacaga atctcaacaa cgacatctag aaaatctcaa
     3181 tcaaattcgt caaactcaag cagatttgca agaattggaa accaaagcca agcggttaga
     3241 acaagataac ttagaacaac taaataataa acaaaatccg attcaggatg tccgtcgaga
     3301 aattgctcaa ttgcaacaac aaattattga caacagcgaa attcgcagtc ctcacgccgg
     3361 ctgcatttta gaaatcatgg ctacagaagg acaagtagtt tcacccggta ctaatttagg
     3421 ttctttgaat gtgaccagcc gcaaaggcac catagttgga gttagttact ttacagttaa
     3481 agatggcaaa aaagtgaaac cggggatgat gattcaaatt acaccggata cagttaagcg
     3541 gcaacgatat ggaggaattg ttggcactgt cacttcagtt tccgagtttc ctattactca
     3601 aaaaggtgtg gcagcagtga ttggcaatcc cgatttggtt agtggattaa ttcaaaatgt
     3661 cagcggcgga gcaggtggag aaaatgcagg gggggcgatt gtagaagtcc gtgcccaatt
     3721 ggaatcagat caaactccca gtggttataa gtggtcatct tcccagggcc cacaactaaa
     3781 aattacccct gggattacca ccactgctag agttcgggtg gaagaacaag cgcctattac
     3841 ctttttacta cccgttctcc gggaatggac tggtgtttat tgatgaaaaa gatgttaaag
     3901 atgggatttt ctaaatcaaa acaacccaaa atcttcaagc gggtaaaaac accaacctta
     3961 ttacaaatgg aagcggtaga gtgtggtgca gccgctttgg gaattattct gagatattat
     4021 ggtcggatcg ttcctttacc cgaactgcgg actaattgcg gtgtctcccg tgatggcagt
     4081 aaagcatcga atgtattaaa agctgctaaa aattatggaa tgcaggcgaa gggatttaaa
     4141 aaacaacttg cccaacttca agaaattcaa cctcccttta ttgtattttg gaacttcaac
     4201 catttcctag tagttgaagg atttacaaaa gaccgtgttt atctcaacga tcccggcact
     4261 ggccctcgga gtgtgagttt tgaggaattc gatcaggctt acactggcgt agttttgctg
     4321 atggaaccgg gcccagagtt taaacgtggt ggccgtaaac ctagcattat tcgctcttta
     4381 atggagcgtt taaaaggctc agtaggggca attatctact gtattttagc tggttttttt
     4441 cttgtaattc cggggttggc tatttccatt tttggtcaaa tctttgtgga taatattctc
     4501 gtcgaaaatc gctatgattg gttgcgaccc ttattaatcg gcataggaat tactgccctc
     4561 attcaagcca gtttaactct gctgcaattg cggtacttaa gacatttaca aatcaaacta
     4621 tctgtgggga tgtcaagccg ctttttgtgg catattctcc gcttaccagt gggattttat
     4681 gctcaaaggt tcgcgggaga aattagcaac cgcgcacagt taaataccag agttgcagat
     4741 gtattatctg gtcagttagc ccaaactgcg atcgatgttg tgatggttat attttatgca
     4801 gcagtgatgt ttgcctatga ctgggtactg actataatca gcatcttctt ggcaatcctt
     4861 aatgtctcaa ccttgcagtg ggtggcagag aaacgcaaag atagtcacat gaggttagtg
     4921 caagatcaag gaaaggcagc aggtgttgcc attgcagggt tacaaagtat tgaaaccatc
     4981 aaatccgcag ccttagaatc agactttttt gctcgttggg ctggatatta tacgaaagca
     5041 gaaaatgctc aacaggaact cggaattagc aaccaagcta tcactgtttt acccaatttc
     5101 atcactgcct taaccactct gtcacttctt attattggcg ggttaagggt gatggatgga
     5161 cacctaagta tagggatgtt agttgctttt caaagtttaa tggctctatt tcagaagcca
     5221 gttaatacct tagtgagttt tggtagtacc cttcaggagt tagagggaga tattaaccaa
     5281 ttagatgatg tgctagataa tgaagttgat tcgcagatta acctagaaaa tcctcaaaat
     5341 ccctttcagg ttgacgcaat acctcgtaca aatggaaaat taactaattc tgcctttaaa
     5401 ttggcaggat atctcgaact tcgcaatctc acttttggct attcacgaat tgacgctcct
     5461 ttagttgaaa atcttagtct cagcttgcga ccaggtcaaa gagtagcctt agtaggaggg
     5521 agtggttctg gtaaatcgac tgttgccaaa acagttgcag ggttatatga agcttggtct
     5581 ggagagattt tatttgatgg tattcctcgt cataaaatcc cccgttctgt gcttacaaat
     5641 tctctatcaa tggttgaaca ggatattttt ctgtttgggg gaaccgtgcg tgaaaactta
     5701 actctatggg atagtacaat tcccaaagat caattattac gtgcttgcca agatgcggcg
     5761 attttagatg tggttttagc tatttctggt ggtattgaag ggaatttgct tgaaggtgcg
     5821 gcaaacttaa gtggcggaca gcgacaacgt ttagaaattg cccgtgcttt ggtaaacgat
     5881 ccttcgatct taattatgga tgaagctacg agtgctttag atgcagaaac tgagaaaatt
     5941 atcgatcaaa atcttcggcg gcggggttgt acttgtttaa ttgttgctca ccgtttgagt
     6001 acgattcgtg actgtgatga gatcattctc ttagatcgag gtaaggttgt acagcgcggt
     6061 actcatgagg aaatgagggc agttcccggc ccttatatgc gcttgattca gtctgagtaa
     6121 aatattattg gtaattggta attggtaatt ggtaattggt aattggtaat tgtaatgtgg
     6181 gcgctcgccg acaactatct tatgctatga tttacaggtt tgttgcggct cgcggccacc
     6241 ctacatttaa ttaaattttg ggtgaagttt tgtactcaaa ttagttaaga accctataaa
     6301 actagacctc tactaaaact tttttagaca gttcgctcac aaaaattggc tcgaattcat
     6361 agatgctaga taacttttct actagcgtat tctcaatgaa ttcccattga tcgttaggtg
     6421 tatatccgct gagacgagaa cgacatacat ctattagttt aggctgaatt tcatttactt
     6481 tcaaaaaatc aatcagtgca tcaattcgtt ctacgatcgc atcctcagaa accttcaaat
     6541 tttcagcgac taatttatca ggttggatga tacaaaagta atacttccca tccatatatt
     6601 tgaccgaggc attcccaccc caacaaatac gcagtttgtt ataaaggtta ttgatatagt
     6661 catagtaagc ctcttctgta atctcaactt ctaaatattc tcccgatacg ttatcacagg
     6721 aaaaatagtc aatatcgata tcgagaatta ccgatttatt taattttttt gattcctcac
     6781 tagagagatc atcttgagca ttaagcggtg taattgtgaa agatttgcaa tcaggattaa
     6841 acaggttatt aaagtcaacc ttcgatttta gtattaatct tttaccttct ccctgatggg
     6901 aatagatatt gagttgtttc tgtccattta attttgggtc gtgtttttga cgcaaccagt
     6961 aaacctgact aaatactcct tgataaagtg caggatagat aaaattagcg attgttaatt
     7021 cgctgtaggt gaagtcatgt acccttttta tattctcatt taccgacttc agagaactat
     7081 ttaaaattgg aactactagg tctgaatgtt catctacatg aagtagcgta ttctgatttt
     7141 tgttaatcca cccttccgct actgcataat gccaaataaa aaatgcttca ttgtgctctt
     7201 ccatgatata aaacggaatc ttagccatag tgattctcct tttttggtaa ttggtaattg
     7261 gtaattgcta atactaattc tgaaaagtat tgctacaatc ctgatgttgg gtttcacttc
     7321 gttccaccca acctactttt actatagttt cagctaccca ggctgaggtt cgtcatcaag
     7381 aacgccacga ttgaacatta aattaagtga gtaataagtt tctgttgcat tcactcctaa
     7441 tttttcaaat tccgcgacga tttcggctgc cgttttattg ccttttaaaa ttgcttctcc
     7501 caattcttta atcaaaggac ggtggcggaa cttgagggtt agaaatcgag tggaaagttt
     7561 gaagccatca tcaagatttt cgtgtttgag gtcgcggcga aatctaagat tctgatcggc
     7621 tctaatttct aaaggcatct gctgagttat cattcgttct aagagaactt tgaggtcatt
     7681 ggcactctca aagtttcctc gatcgtaaac tcgatagcca ttaggccagc gatcgtcagc
     7741 tttgcaagga ctaataattt taacgctgcg ctcgaccatg ttaaacaaaa atcctgttac
     7801 acaagcaatc gttgattggg ctaactcatc agatgcttct ccagctttat tttgcttttc
     7861 ccaggaacga ccagccactg ctttattcat cagcgactcc ttattttgca tgactaaacc
     7921 gacgcggatt agatcctctg gcgagaattc tgcatataca ttttgtaaaa ttttgaggga
     7981 caaaatagag aagcgatggt aagtaaaacc ctgagagtct gagaatttca aaagcgatcg
     8041 cacccgtgct ggatatttca tgggttgggc agtcgtcatt tgtggaattg cgcctaaaat
     8101 ggcttgaaaa tcgctgacaa actgttcata atcggggtta tcaagggggt cagttgccca
     8161 gtaacaaaag ccagtaccgg cagcagggcc acaaatttct ttaataactt ctaacacttc
     8221 gccccaaagt tgggcatttt cggcggtgta agtaaagata tcgctaaaac gcggtgctga
     8281 aatcccgcaa aatgaacagc caacagaaca tcctttagtc agttcaaaag caacaggtgc
     8341 atggagaatt tgagcgttat gagatttgcg aatttcgctg tctccgcgtg caatttgccg
     8401 atcgcgccac gcctgaaatc tcggatcgct atccggcata ttattgcgcc agcgaaaaaa
     8461 atatcgttcc cgtgcttttt cgtagtcaat gaaacgttgg agggcgatgg gaaatgggat
     8521 gtcttgggat tgttggcttt ttacaaattc cgcgtcccat aaccagcgaa tttctgctaa
     8581 gggaattttg agattgtatt gagccactgt ttgttcgggt gcgatcgcca cattttttct
     8641 aaattctgga tcggcttcgt aatattccgt aaatcgcttg atatggctga tactcgttaa
     8701 ttcttgctcg tctaatttca tccaccgctc gatcgttttt tgttctagcg cgtcatctaa
     8761 ttgagccaat tggggagcca aaggtaatgt cttagcagtc attttccgaa tcctctgtga
     8821 tagtttttct gatcgtttta aactcaaaac tcttttgctt catttccaca acaatagaga
     8881 tggcagtaag tcgggataag ctaggcgcag cagttgataa ccaattcccg cagttcccgt
     8941 aaacagacca gggctgtatg tatcccctgc cacattagca aatacttgga aagatcccgt
     9001 ttgtcgggcg cgagttacta cccaagcagc ttgttgttgg gcaatagtaa ttaattccgg
     9061 tcgatttaag cgttttcctg cttctagaaa tagctcgagc cgcccgaaat taccacagca
     9121 ataattgtct atttcttcgg ctttgacttg cggcgtagct gcgatcgcaa attcaatatc
     9181 ttgctgaatt tccgccgaat taagcatttc caaacttccc agccgtgcta aacctattcc
     9241 tggcgcacca tgacaccaag tgttcgtaaa actgggttct ccgttacggc tgacggagtt
     9301 tctaaaatct ggccagttac ctgcttttgg tgagaaaacg ctgcgttcgt aagcgatcgc
     9361 ttctgctgct gcttctagaa atacaacctc gttgctgact ttatataacc gcaataaggc
     9421 ataagcaatc cccgccgcac cgtgagaaaa tcctgttagt aacttgccat caacggtttg
     9481 ccaagttctg aatccggagt cgctagcagt gcggtattga agtaaatgct ttcctcctgc
     9541 gatcgcttgt tctaaaatgg ctggttcttt ggttacttcg tagagcgcta acagtcctaa
     9601 aatcgctccg gctgtgccga aagtaacatc aaacttgcga tcgtcggcaa atttttctgg
     9661 tgttaataaa gcagcagctt tggttgcatc ctcaattaca gcgctatttt ctagaaattg
     9721 gccaattcga gttaacccgt agattataga accgcatccc acagcaccgc caatcccaat
     9781 tttttgcacc atagcgcgac taatttgagg attttgtaaa tgctgacgca gagattcgat
     9841 cgctgctaaa gttagttctt gaagttctga atttccttga attttggcta aagctgatag
     9901 aaatatgcca attccacaac tgccgtcata gagccgatcg cttacaggtt ctagttgaaa
     9961 gcgctggatc tccattaagt aaactagagc aatccaactg gcgctaccat tgggagaatg
    10021 aagggcattg ttttggaggc gtttggcgat cgcttcggct tctcggacta aatcttttga
    10081 atccagttgt gggactaaat cgagctggag ttctaaactt gggcttaaac tagaactctc
    10141 gcattgtttg gcaatctgtg cgtagaggga accgcgaatt agtccaattt gccattttag
    10201 gtcatctgcg ctcaattgtt gcaatcgagc gatcgctaag tcgatacttg gttgggcaaa
    10261 gcagttttca atggtttcat tagtagcgat cggcaaagca tcttgattag cccaagctgt
    10321 aaataaggga atatccatat actctagtgc ttgtttttcg gctgcaatca actgcccaac
    10381 tgctccctcg ctattgcgtc gcaagctatg aaatttgtca ttccaaaatc gctctctact
    10441 caaataatct aactgaatgc tgcgatttgc accatctttc agagcctcta atttcagcga
    10501 catttctagt atgacgcaat aaatttttgt tgctctgaaa gtgaagcgca cttgctgttt
    10561 gcccagattc attaaagggc tatctgctgt caaaagtgcg tcgcgctgtt ctcggagaaa
    10621 ctggtacatt tgccgaaacc cagcgatgag ttcttctaaa taattgctgg gggaaagtcc
    10681 cacaccattt agatacggta tgtttttacc aggtggcatc gcctcataat ccgaacctag
    10741 aaccatgtca tctttattga cgttctgcca tttcgttact ttaaagagcg tttcttgctg
    10801 gctgccactt cccaaacctg aaacgtcaag gctttgccct gtggctacaa atagccatct
    10861 aggaagtaat cccgtatcca atacggagct atacatttgt tcgtaagcga gggaataggc
    10921 atctcgatcg gcggtgctaa cttccccccg cacgccatga tttaagagca tttctaaatc
    10981 gatggggacg ggatattcgc cacaagcaat aatattttca tcaagaaagt ctgtgccttt
    11041 gaggacgtag gctaggcaga gaaacatccc catccgttga tagtagcgac tagcttgtgc
    11101 ttggttttga caaggtagat gttcgataaa ttctgcccag ccataggttg agcgatcgat
    11161 gattttttgc ggtttaaagg ttaagggaat atctctgtta tttaaccaag tgagtaactg
    11221 gctgtaagct ttttctgtac caaggctttt gggtttgtaa accagttcta agcctgagct
    11281 aaatagaatt gcgatcgcgg aacgcccttg acggtggcga tcggaaaggt tgggttgaat
    11341 aactgtaact tgacccagct ctgtttccgg ttggaaagtt tgctgaattt cactccaatc
    11401 tgaagctaat ctttgcagga attcagttgt tgtttctacc cataagttta ccagcgtccc
    11461 ggctagacgt gccaatacgg aatactcttg gaaaaatgtt attaattctc cgttcagcaa
    11521 gtcttcgata aattgcttgt attgtttgtt agtataggtg acagttaatg gccaggagct
    11581 aactaaggca ggttgttttt gctgttgaaa gattttaaat ttctgaaata atgcccgcga
    11641 gcccaaattt gctaacaatt ctagcaggct gcgttctaag ttggcgtggg cggctgcggt
    11701 tagcagtgag tagctatttc cggtgttcgc gattagtttt tctctggcga tgtaaactga
    11761 agacagccaa atttcttcaa agggtaaagg gcgcagggga ttgagaaatg ctaaattgtc
    11821 tttggcgatc gcagttctgg cttgtaagct ctcttctagg gtttgagccc atgctggtaa
    11881 gcgatcgccc tgaaagcgaa cgttactaac agcgttgcgg gctgagttta aatctaaacc
    11941 catctggctc aggtgttgct ggaattttgc gaaatctcct tcagctacaa cttgacacca
    12001 ctgtttgatt cgggcattaa taatgtctgg gctctcgcta gctgaatcga aggcaaaatt
    12061 agagttaagg cgttcgtcga tcgtgctagc tttttcaaca attttaatta aatctttttt
    12121 acaaacttgc attttttcta agtcctattg ctaattgcta attgctaatt gctaatttgg
    12181 ataaaaaaga ggaagcaaaa cttattcaag tgcttagctt cctcttctta gactagctcc
    12241 agaaactgct gtctaaatcg cattaagtgc gagttacaaa accgcagcca cggctaccag
    12301 caatccagca accgccacca gcgacagctt ctaattgttc ttcagataat tcttcttcaa
    12361 cagcttcagg agcaggtaga actaagtaca tcttagtagc tgtttcttct actacttcaa
    12421 ttgtcagatc gtctggcact tgagtgttaa actctgaaga aatcactgct ttaggattgg
    12481 ctttgagttt ttcgcggaag ctgggatctt taagagcttt gatggcgagt tgttcttcgg
    12541 cttctttgcg agtagacatg atgtttttcc tgttttaaat gaatgggttt aagaggtgtc
    12601 tttgcgatgt tcgcttgacg tttgattctt gctcgaatct tttatcagaa taaccagtcc
    12661 ttcccagtac cgtcaatata gaaaagttca gtaaaactca ggagttagaa acaaaattta
    12721 attattttct taactttggt cagaaaaact ctgataaatt caggtcaggt acacttttgt
    12781 tagcaaaaag cctaagtttt aaaccatgaa cgtcagtcag gcactagaat tggcagataa
    12841 tttggtggtg gctaaaacgg ccaggcactt gagcgacttg caaagacttt tattagagga
    12901 attttggacg aggccaagtt tgcgctatga cgaagttgcc caaactcacg gctattcagc
    12961 tagctatctc aagcaagatg caggcccgaa actgtggcga tcgctctccg atgcttgtgg
    13021 cgaaaaggta agcaaggcga actttcgagc agcgctagag cgaaaatggt ctgcggtggg
    13081 agagaagagg aacctatctt taccagaaaa ctcggataac tatcctgtca gcgttgtgca
    13141 gcaagatcct tccacttcat cgctagcagt tttagccccg cccacaagct acccaactca
    13201 agatttattg agctccccgg ttgtaccgcc tgacgacaat ttgccacccg cacaactcca
    13261 gagttatcaa gattggggga ttgcgcctga tgtttccacg ttttacgatc gctacgagga
    13321 aatagctcaa cttaaacaat ggattgtagg cgatcgctgt cgtttagtcg cgatcgttgg
    13381 tttaggaggc attggcaaaa cctatctcag cgtgaaatta gctgaacaaa tccaagattg
    13441 ttttcaatac gtgatttggc gatcgctgcg aaatgctcca cccctacaac aaattttaac
    13501 gagcattctg caatcaattg ctaatagtca agaaatcgat ttagctgcaa cagtccatga
    13561 aaaaatctct tgcgccatcg attttttccg caaccatcgt tgcttgttga ttttagataa
    13621 tgtcgaaacg attctacagg gtggtgttta cacgggttat taccaagaag gttatgaaga
    13681 ttacggtgaa ttttttaagt gtttaggaga gggtcgtcac catagctgct tgctactaac
    13741 cactcgtgaa aaaccgaaag aaatttcgat aatgcagggg gaaactttac caattcgctg
    13801 cttgcgactg caaggtttat ctacctccgc aggtttgcaa ctattacgcc tcaaaggttg
    13861 ttactggaca tcagaacaag aggggtttgc tttagttgaa cagtatgctg gtcatcccct
    13921 tgccttaaag attattgcct cgacgattcg agaattattt gaaggtaata tttcagagtt
    13981 tactcaacat aacctattgg tgattgatga aatacgtact ctcttagaag aacagtttaa
    14041 tcgtttaacc gacttaggca aagctttatt ttactggata gctattaatt tagaaccagt
    14101 atcagcagag gaattatatt ctgatattta tcccctggtt tccaaacctc ggttagttga
    14161 aactttaaag tctttagtgc aacgttcgct gatcgaacaa accggcagtc agtttgtctt
    14221 gcagcccgta gtgagggaat atgcgatcgg ctctttagtc aagcaagttt gcgaagagat
    14281 tgaaacggga aactttgcga ttttaaacag tcatgctctg ctcaaagctc aggcaaaaga
    14341 ctatatccga caaacccaaa tcaagtttat tctcaatccc atcctcgaaa ggttattaac
    14401 agcattcaaa accaaagcta ggattgcaaa tcactttaaa caattgatac atgagctgca
    14461 aatgcagcca tctcaatcgc ctgggtatgc agccggaaat ctgctgaata ttctatgtca
    14521 aatgcagatc gatgtcagcg gctatgattt ttctcatctc acagtttggc aagcttattt
    14581 gcaaggcaca aacctacatg atgtcaattt taaaggtgca gatttagcta aatccgtgtt
    14641 tgccaaacag ctaaccaatg ttttagcact tgcctttagt cccgatggca cgctattagc
    14701 aaccggagac gctaatggag aaatttgctt gtggttagca gacgacggta cgctgttaag
    14761 aatttacgaa ggacacgcag gttgggtaaa ttcaattgcc ttcagcccaa atggtagctt
    14821 actgtgtagc gggagtagcg atcgcaccgt caaaatttgg gacgtaggca ccggaaactg
    14881 cctgaaaacc ctctcaggac acaatcaacg agtacggacg gtggccttca gtcctgacag
    14941 tcaaaccgta gccagcagca gcagcgatcg cacagtccga ttgtgggaca ttcaaagcgg
    15001 ttggtgtcaa caaatttacg caggtcatac cagttacgtc tggtcagtaa cttttagtcc
    15061 caacggcaga accctcgcca gtggtagcga agatcgtacc atcaaactct gggacgttct
    15121 cacagggaaa tgcttgcaga catggcagga ttctagcagt tgggttcgca ccctcgcctt
    15181 cagtccagac ggcaaaacct tagccagcgg cggaggcgat cgcaccgtca aactatggga
    15241 aactagcaca ggaaccctat tagcatcact ccccggacac tcccaacgtt tgcgttccct
    15301 cgcttttagc cccgatggta aactacttgc cagtggtagt ggcgatcgca ccgtcaaaat
    15361 ctgggactta acagcaaagc gctgcctgaa aacactacac ggccatagca gtcgcctctg
    15421 cgccgtcgtc tttagtcccg atggcaacac cctagtcagc ggtggcgaag accgcaccgt
    15481 caggttttgg gaagtgagta cgggtaactg caacagcatt tggcaaggtt acgccagttg
    15541 gtttcaatcc gtcgccttca gtcccgatgg caaaacccta gccagcggca gcgaagatgg
    15601 tacagtcaag ctttggaaaa ctaaccttaa ctcctctggc ccttgcagtc ccattacctt
    15661 actaggccat gcaggttggg tttgttccgt cgcctttagt cccgatggca caaccttagc
    15721 tagtgccagc agcgactaca cgattaaatt atgggatgct agcagcggca cttgcctgaa
    15781 aaccttacta ggaaacccgc gctggattcg gtctatagca tttagccccg atgggaaaat
    15841 gttagctagt ggtggtggtg acaataccgt aaaattatgg aaccttcgtt ctggcaactg
    15901 ttgcgccacc tggcgatcgc acgcaggttg gttgtggtca gtcgccttta gtcctaatgg
    15961 tgcgatcgtt gccagcgcca gcgaagacaa aaccgtaaaa ttatggtgcg tccacacagg
    16021 aagatgttta agaacctttg aaggacatag cagttgggtg caagcagtcg cctttagtcc
    16081 cgatggaaga ctattagcta gtggcagttg cgaccaaact attaaactct gggatattga
    16141 tacaggtcaa tgcctgcaaa ccttttggga tcatgtgagt tgggtgcaaa cagtcgcctt
    16201 tagtcccgat ggcaaattct tagcgagtgg aagttgcgat caaaccgtaa aattttggga
    16261 aattgacagc ggtgagtgtt ggcaaactct atcggcacat acaaactggg tttgggcgat
    16321 cgcatttagt ccgaatggtg acattttagc cagtgccggt caagacgaaa ccattaaatt
    16381 gtggaaagtc agcaccggcg aatgcttaga aactcttaga agtaaaaggc tttatgaagg
    16441 aatgtgtttg agggaatcta cacatttaac agaagcacag ttagcaacac tcaaactttt
    16501 aggggcattt gtttag
//
