BGC0002334: heptyltyrazolone biosynthetic gene cluster from Pseudoalteromonas rubra
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Location: 468,545 - 486,062 nt. (total: 17,518 nt).
This entry is originally from NCBI GenBank AHCD03000035.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002334
Short description heptyltyrazolone biosynthetic gene cluster from Pseudoalteromonas rubra
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • other (other)
  • ribosomal (RiPP)
Loci
AHCD03000035.1
468545 - 486062
via Heterologous expression, Enzymatic assays
Compounds
  • heptyltyrazolone
  • nonyltyrazolone
  • undecyltyrazolone
  • (Z)-ω-6-undecenyltyrazolone
Species Pseudoalteromonas rubra [taxonomy]
References
Chemical products information
heptyltyrazolone Evidence: NMR [1]
Copy SMILES
Chemical database entries
NPAtlas
nonyltyrazolone Evidence: NMR [1]
Copy SMILES
Chemical database entries
NPAtlas
undecyltyrazolone Evidence: NMR [1]
Copy SMILES
Chemical database entries
NPAtlas
(Z)-ω-6-undecenyltyrazolone [synonyms: (Z)-6-undecenyltyrazolone] Evidence: NMR [1]
Copy SMILES
C21H27N1O3
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • PRUB_a0528
  • KAF7786076.1
468545 - 469384 (+) hypothetical protein
    copy AA seq
    copy Nt seq
    • PRUB_a0529
    • KAF7786077.1
    469595 - 470434 (+) hypothetical protein
      copy AA seq
      copy Nt seq
      • PRUB_a0531
      • KAF7786078.1
      471194 - 473038 (-) hypothetical protein
        copy AA seq
        copy Nt seq
        • PRUB_a0532
        • KAF7786079.1
        • acnB
        473387 - 476176 (-) aconitate hydratase 2 / 2-methylisocitrate dehydratase
          copy AA seq
          copy Nt seq
          • PRUB_a0533
          • KAF7786080.1
          476449 - 478443 (-) oxazolone synthetase
            copy AA seq
            copy Nt seq
            • PRUB_a0534
            • KAF7786081.1
            478453 - 479202 (-) tyrosine N-acyltransferase
              copy AA seq
              copy Nt seq
              • PRUB_a0536
              • KAF7786082.1
              479558 - 480613 (-) hypothetical protein
                copy AA seq
                copy Nt seq
                • PRUB_a0538
                • KAF7786083.1
                • rimK
                480600 - 481505 (-) ribosomal protein S6--L-glutamate ligase
                  copy AA seq
                  copy Nt seq
                  • PRUB_a0539
                  • KAF7786084.1
                  481507 - 481953 (-) hypothetical protein
                    copy AA seq
                    copy Nt seq
                    • PRUB_a0540
                    • KAF7786085.1
                    482293 - 484812 (+) iron complex outermembrane recepter protein
                      copy AA seq
                      copy Nt seq
                      • PRUB_a0541
                      • KAF7786086.1
                      485038 - 485556 (+) hypothetical protein
                        copy AA seq
                        copy Nt seq
                        • PRUB_a0542
                        • KAF7786087.1
                        485595 - 486062 (-) hypothetical protein
                          copy AA seq
                          copy Nt seq
                          Biosynthesis information
                          Annotation changelog

                          Entry version: next

                          Date
                          Changes
                          Submitters
                          Reviewers
                          MIBiG v4 annotathon
                          • (ID: 3NQIBNAT6ZIBJV3NZKMFJFBW)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                          Entry version: 2

                          Date
                          Changes
                          Submitters
                          Reviewers
                          Added chemical structures for compounds: heptyltyrazolone, (Z)-heptylphenazolone, nonyltyrazolone, undecyltyrazolone, (Z)-6-undecenyltyrazolone.
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          Added NPAtlas links to compounds: heptyltyrazolone, (Z)-heptylphenazolone, nonyltyrazolone, undecyltyrazolone, (Z)-6-undecenyltyrazolone.
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          Renamed compounds: heptylphenazolone to (Z)-heptylphenazolone, ω-6undecenyltyrazolone to (Z)-6-undecenyltyrazolone.
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                          Entry version: 1

                          Date
                          Changes
                          Submitters
                          Reviewers
                          Entry added
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          Similar known gene clusters from MIBiG 4.0
                          Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
                          Click on reference genes to show details of similarities to genes within the current region.
                          Click on an accession to open that entry in the MiBIG database.