BGC0002340: pyrroloformamide A biosynthetic gene cluster from Streptomyces sp. CB02980
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Location: 1 - 28,112 nt. (total: 28,112 nt).
This entry is originally from NCBI GenBank JACSCH020000013.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
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NRP
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NRPS/PKS domains
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General information about the BGC
MIBiG accession BGC0002340
Short description pyrroloformamide A biosynthetic gene cluster from Streptomyces sp. CB02980
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
  • Other
Loci NCBI GenBank: JACSCH020000013.1
Compounds
  • pyrroloformamide A
  • pyrroloformamide B
  • pyrroloformamide D
  • pyrroloformamide C
Species Streptomyces sp. CB02980 [taxonomy]
References
Chemical products information
pyrroloformamide A
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Chemical database entries
NPAtlas
pyrroloformamide B
(no structure information available)
pyrroloformamide D
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Chemical database entries
NPAtlas
pyrroloformamide C
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Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • E0F75_025300
  • MCB8905699.1
 195 - 992 (+) putative protein N(5)-glutamine methyltransferase
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  • E0F75_025305
  • MCB8905700.1
 1085 - 1723 (-) NAD(P)H-dependent oxidoreductase
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  • E0F75_025310
  • MCB8905701.1
 1886 - 2785 (+) shikimate dehydrogenase
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  • E0F75_025315
  • MCB8905702.1
 2782 - 3630 (+) metallophosphoesterase
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  • E0F75_025320
  • MCB8905703.1
 3627 - 4331 (+) 4'-phosphopantetheinyl transferase superfamily protein
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  • E0F75_025325
  • MCB8905704.1
 4563 - 4982 (+) ASCH domain-containing protein
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  • E0F75_025330
  • MCB8905705.1
 5051 - 5728 (-) GAP family protein
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  • E0F75_025335
  • MCB8905706.1
 5952 - 6962 (+) NAD(P)/FAD-dependent oxidoreductase
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  • E0F75_025340
  • MCB8905707.1
 7032 - 7634 (-) XRE family transcriptional regulator
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  • E0F75_025345
  • MCB8905708.1
 7872 - 9032 (-) acyl-CoA dehydrogenase family protein
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  • E0F75_025350
  • MCB8905709.1
 9036 - 9791 (-) thioesterase
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  • E0F75_025355
  • MCB8905710.1
 9788 - 11428 (-) GMC family oxidoreductase N-terminal domain-containing protein
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  • E0F75_025360
 11503 - 14778 (-) amino acid adenylation domain-containing protein
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  • E0F75_025365
  • MCB8905711.1
 15044 - 15637 (+) flavoprotein
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  • E0F75_025370
  • MCB8905712.1
 15755 - 16162 (-) RidA family protein
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  • E0F75_025375
  • MCB8905713.1
 16224 - 17687 (-) FAD-dependent oxidoreductase
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  • E0F75_025380
  • MCB8905714.1
 17830 - 18579 (-) methyltransferase
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  • E0F75_025385
  • MCB8905715.1
 18664 - 19941 (-) MFS transporter
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  • E0F75_025390
  • MCB8905716.1
 20258 - 20770 (-) group II truncated hemoglobin
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  • E0F75_025395
  • MCB8905717.1
 20831 - 21715 (-) AfsR/SARP family transcriptional regulator
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  • E0F75_025400
  • MCB8905718.1
 22056 - 23021 (-) methyltransferase domain-containing protein
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  • E0F75_025405
  • MCB8905719.1
 23018 - 23875 (-) thioesterase
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  • E0F75_025410
  • MCB8905720.1
 23872 - 24480 (-) hypothetical protein
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  • E0F75_025415
  • MCB8905721.1
 24951 - 28112 (+) DUF2791 family P-loop domain-containing protein
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
E0F75_025360
Module ?
Specificity: cysteine
Evidence for specificity:
  • Structure-based inference
  • Feeding study
Annotation changelog
MIBiG version Submitter Notes
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Entry added
  • Added NRP substrate specificities
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Added chemical structures for compounds: pyrroloformamide A.
  • Added NPAtlas links to compounds: pyrroloformamide A.
Detailed domain annotation
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