BGC0002342: myxofacycline C biosynthetic gene cluster from Myxococcus xanthus
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Location: 8,235 - 29,793 nt. (total: 21,559 nt).
This entry is originally from NCBI GenBank MT513750.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002342
Short description myxofacycline C biosynthetic gene cluster from Myxococcus xanthus
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
  • PKS (Unknown)
Loci
MT513750.1
8235 - 29793
via Knock-out studies, Heterologous expression
Compounds
  • myxofacycline C
  • myxofacycline D
  • myxofacycline G
  • myxofacycline E
  • myxofacycline A
  • myxofacycline F
  • myxofacycline B
Species Myxococcus xanthus [taxonomy]
References
Chemical products information
myxofacycline C Evidence:
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Chemical database entries
NPAtlas
myxofacycline D Evidence:
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Chemical database entries
NPAtlas
myxofacycline G Evidence:
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Chemical database entries
NPAtlas
myxofacycline E Evidence:
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Chemical database entries
NPAtlas
myxofacycline A Evidence:
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Chemical database entries
NPAtlas
myxofacycline F Evidence:
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Chemical database entries
NPAtlas
myxofacycline B Evidence:
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Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • QKW94306.1
  • iso1
 8235 - 8648 (+) hypothetical protein
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    • QKW94305.1
    • iso2
    		 8803 - 12453 (+) AMP-dependent synthetase/ligase
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      • QKW94283.1
      • iso3
      		 12496 - 13338 (+) fatty acid desaturase subfamily protein
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        • QKW94290.1
        • iso4
        		 13386 - 14228 (+) hypothetical protein
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          • QKW94294.1
          • iso5
          		 14298 - 17063 (+) short-chain dehydrogenase/reductase SDR
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            • QKW94304.1
            • iso6
            		 17092 - 20379 (+) non-ribosomal peptide synthetase
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              • QKW94302.1
              • iso7
              		 20376 - 20750 (+) short-chain dehydrogenase/reductase SDR
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                • QKW94281.1
                • iso8
                		 20798 - 22378 (+) long-chain-fatty-acid--CoA ligase
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                  • QKW94285.1
                  • iso9
                  		 22411 - 29793 (+) short-chain dehydrogenase/reductase SDR
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                    Biosynthesis information
                    Annotation changelog

                    Entry version: 2

                    Date
                    Changes
                    Submitters
                    Reviewers
                    2022-10-07
                    Changed chemical structures for compounds: myxofacycline D, myxofacycline G, myxofacycline A, myxofacycline E, myxofacycline F, myxofacycline C, myxofacycline B.
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    2022-10-07
                    Added NPAtlas links to compounds: myxofacycline D, myxofacycline G, myxofacycline A, myxofacycline E, myxofacycline F, myxofacycline C, myxofacycline B.
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    2022-10-07
                    Renamed compounds: myxofacyclin D to myxofacycline D, myxofacyclin G to myxofacycline G, myxofacyclin A to myxofacycline A, myxofacyclin E to myxofacycline E, myxofacyclin F to myxofacycline F, myxofacyclin C to myxofacycline C, myxofacyclin B to myxofacycline B.
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                    Entry version: 1

                    Date
                    Changes
                    Submitters
                    Reviewers
                    2022-09-15
                    Entry added
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    Detailed domain annotation
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