BGC0002348 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002348 (Aspergillus terreus NIH2624)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS-like	1	18,134	aspulvinone E	NRPS:Type I	100%

BGC0002348 - Region 1 - NRPS-like

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Location: 1 - 18,134 nt. (total: 18,134 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 18,135
Label		BGC0002348

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002348	1.00	NRP	aspulvinone E	Aspergillus terreus NIH2624
BGC0002274	0.41	NRP	aspulvinone H, aspulvinone B1	Aspergillus terreus NIH2624
BGC0002193	0.36	Other	phenguignardic acid	Aspergillus terreus NIH2624
BGC0002277	0.33	NRP	atromentin	Suillus grevillei
BGC0001668	0.24	NRP	microperfuranone	Aspergillus nidulans FGSC A4
BGC0000442	0.22	NRP	terrequinone A	Aspergillus nidulans FGSC A4
BGC0002271	0.21	NRP	asterriquinone CT5	Aspergillus terreus NIH2624
BGC0001712	0.17	Other	ochrindole A	Aspergillus steynii IBT 23096
BGC0001168	0.17	NRP	livipeptin	Streptomyces lividans 1326
BGC0002596	0.15	Polyketide	lecanoric acid, orsellinic acid	Claviceps purpurea 20.1

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002348	1.00	NRP	aspulvinone E	Aspergillus terreus NIH2624
BGC0002274	0.73	NRP	aspulvinone H, aspulvinone B1	Aspergillus terreus NIH2624
BGC0002193	0.69	Other	phenguignardic acid	Aspergillus terreus NIH2624
BGC0002277	0.66	NRP	atromentin	Suillus grevillei
BGC0001668	0.58	NRP	microperfuranone	Aspergillus nidulans FGSC A4
BGC0000442	0.55	NRP	terrequinone A	Aspergillus nidulans FGSC A4
BGC0002271	0.54	NRP	asterriquinone CT5	Aspergillus terreus NIH2624
BGC0001712	0.48	Other	ochrindole A	Aspergillus steynii IBT 23096
BGC0001168	0.48	NRP	livipeptin	Streptomyces lividans 1326
BGC0002596	0.45	Polyketide	lecanoric acid, orsellinic acid	Claviceps purpurea 20.1

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 18134:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ATEG_03563

AMP-binding (10..434): X

nrpys: 4-ohPpa

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic (Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr)
Large clusters prediction:: Aromatic side chain (Phe, Trp, Ph-Gly, Tyr, bOH-Tyr)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: VAIFAGGAGK
Nearest Stachelhaus code(s):: 4-ohPpa VAIFAGGAGK (100% 8Å match)
Stachelhaus code match:: 100% (strong)