BGC0002362 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002362 (Micromonospora endolithica)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	T3PKS	1	24,294	High	loseolamycin A1/loseolamycin A2	PKS

BGC0002362 - Region 1 - T3PKS

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Location: 1 - 24,294 nt. (total: 24,294 nt) Show pHMM detection rules used

Region on contig edge.

T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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Gene overview

MIBiG

Tailoring

MIBiG comparison

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 24,295
Label		BGC0002362

Tailoring functions

Oxidoreductases: dehydrogenase

QZS07513.1: Hydroxylation

MITE: MITE0000081Hydroxylation (identity: 77.00%)
smcogs: SMCOG1006: acyl-CoA dehydrogenase

Transferases: Prenylation methyltransferase

QZS07499.1: methyltransferase

smcogs: SMCOG1089: methyltransferase

QZS07500.1: methyltransferase

smcogs: SMCOG1089: methyltransferase

QZS07511.1: Prenylation

MITE: MITE0000083Prenylation (identity: 62.70%)

QZS07512.1: methyltransferase

smcogs: SMCOG1089: methyltransferase

Hydrolases: deformylase

QZS07506.1: peptide deformylase

smcogs: SMCOG1275: peptide deformylase

Ligases: synthase

losA: chalcone and stilbene synthase domain protein

smcogs: SMCOG1024: chalcone and stilbene synthase domain protein

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002362.3	1.00	PKS	loseolamycin A1, loseolamycin A2	Micromonospora endolithica
BGC0001077.4	0.78	PKS	6-anteisoheptadecyl-4-O-dihydrogeranyl-2-methoxyhydroquinone, 6-isoheptadecyl-4-O-dihydrogeranyl-2-methoxyhydroquinone, 6-isopalmityl-4-O-geranyl-2-methoxyhydroquinone, 6-palmityl-4-O-geranyl-2-methoxyhydroquinone, 6-anteisoheptadecyl-4-O-geranyl-2-methoxyhydroquinone, 6-isoheptadecyl-4-O-geranyl-2-methoxyhydroquinone, 6-isopalmityl-4-O-dihydrofarnesyl-2-methoxyhydroquinone, 6-palmityl-4-O-dihydrofarnesyl-2-methoxyhydroquinone, 6-anteisoheptadecyl-4-O-dihydrofarnesyl-2-methoxyhydroquinone, 6-isoheptadecyl-4-O-dihydrofarnesyl-2-methoxyhydroquinone	Actinoplanes missouriensis 431
BGC0001591.4	0.37	other (other)	fatty acid enol ester, N-tetradecanoyl tyrosine	uncultured bacterium CSLC2
BGC0001521.3	0.36	NRPS	auriculamide	Herpetosiphon aurantiacus DSM 785
BGC0000826.5	0.34	other (other)	staurosporine	Streptomyces clavuligerus ATCC 27064
BGC0000827.3	0.33	other (other)	staurosporine	Salinispora arenicola CNS-205
BGC0001985.4	0.33	other (other)	Pyrazofurin	Streptomyces candidus
BGC0000700.5	0.33	saccharide	istamycin	Streptomyces tenjimariensis
BGC0001964.2	0.32	PKS	alkylpyrone-407, alkylpyrone-393	Cystobacterineae bacterium
BGC0001122.4	0.32	NRPS, PKS	dihydroisoflavipucine, isoflavipucine	Aspergillus terreus NIH2624

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002362.3	1.00	PKS	loseolamycin A1, loseolamycin A2	Micromonospora endolithica
BGC0001077.4	0.78	PKS	6-anteisoheptadecyl-4-O-dihydrogeranyl-2-methoxyhydroquinone, 6-isoheptadecyl-4-O-dihydrogeranyl-2-methoxyhydroquinone, 6-isopalmityl-4-O-geranyl-2-methoxyhydroquinone, 6-palmityl-4-O-geranyl-2-methoxyhydroquinone, 6-anteisoheptadecyl-4-O-geranyl-2-methoxyhydroquinone, 6-isoheptadecyl-4-O-geranyl-2-methoxyhydroquinone, 6-isopalmityl-4-O-dihydrofarnesyl-2-methoxyhydroquinone, 6-palmityl-4-O-dihydrofarnesyl-2-methoxyhydroquinone, 6-anteisoheptadecyl-4-O-dihydrofarnesyl-2-methoxyhydroquinone, 6-isoheptadecyl-4-O-dihydrofarnesyl-2-methoxyhydroquinone	Actinoplanes missouriensis 431
BGC0001591.4	0.37	other (other)	fatty acid enol ester, N-tetradecanoyl tyrosine	uncultured bacterium CSLC2
BGC0001521.3	0.36	NRPS	auriculamide	Herpetosiphon aurantiacus DSM 785
BGC0000826.5	0.34	other (other)	staurosporine	Streptomyces clavuligerus ATCC 27064
BGC0000827.3	0.33	other (other)	staurosporine	Salinispora arenicola CNS-205
BGC0001985.4	0.33	other (other)	Pyrazofurin	Streptomyces candidus
BGC0000700.5	0.33	saccharide	istamycin	Streptomyces tenjimariensis
BGC0001964.2	0.32	PKS	alkylpyrone-407, alkylpyrone-393	Cystobacterineae bacterium
BGC0001122.4	0.32	NRPS, PKS	dihydroisoflavipucine, isoflavipucine	Aspergillus terreus NIH2624

Similar known clusters from MIBiG 4.0