LOCUS       BGC0002365             17258 bp    DNA     linear   BCT 13-DEC-2019
DEFINITION  Streptomyces sp. strain SCSIO40010 fatty acid hydroxylase,
            polyketide synthase/non-ribosomal peptide synthetase, FAD-dependent
            oxidoreductase, alcohol dehydrogenase, and cytochrome P450 genes,
            complete cds.
ACCESSION   BGC0002365
VERSION     BGC0002365
KEYWORDS    .
SOURCE      Streptomyces sp
  ORGANISM  Streptomyces sp.
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 17:26:32
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 17258
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..17258
                     /db_xref="taxon:1931"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces sp."
                     /strain="SCSIO40010"
     protocluster    1..17258
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[1681:11086]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1682..11086
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     protocluster    1..17258
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[1681:11086]"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      1682..11086
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
     cand_cluster    1..17258
                     /SMILES="C([*])C(-O)NC(CCCN)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="chemical_hybrid"
                     /product="T1PKS"
                     /product="NRPS"
                     /protoclusters="2"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..17258
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0002365"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..17258
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /subregion_numbers="1"
                     /tool="antismash"
     CDS             661..1671
                     /codon_start=1
                     /note="PtmD'"
                     /product="fatty acid hydroxylase"
                     /protein_id="QGU18618.1"
                     /transl_table=11
                     /translation="MDEYGRSADGEIDSVGHAGRGNPRNGWNGEKGAVDAVGIIAARVL
                     RVVAYPLLLLAVVSVGAAALVLRWDPAIVSPLFLIGTLMYLALLEQLIPYERSWHPGKD
                     EWRWYGVYFLLTMAGSGLAQLLVTAAVGWIAADERSHHLWAEIPGALLAGSLVSYLVHR
                     LGHTSALLWRLHGVHHVPQKVNVANNGVNHVLDIVLAQSLVQLTLALAGFSRSAVLVTG
                     LFVVAQGYFVHANIDVRIGRFNHLLASPEQHRLHHSTDLSEAGHYGSDLSCWDHLFGSF
                     TWHPGREPAAVGLHDPASFPATGEIVASTLHPWRRRPPPGDPAGPDANPRSSTTT"
     CDS             1682..11086
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (15-442). E-value:
                     2.3e-177. Score: 582.0. Matches aSDomain:
                     nrpspksdomains_QGU18619.1_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (557-853). E-value: 6.5e-103.
                     Score: 336.0. Matches aSDomain:
                     nrpspksdomains_QGU18619.1_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (915-1076). E-value: 1.9e-34.
                     Score: 111.3. Matches aSDomain:
                     nrpspksdomains_QGU18619.1_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_KR (1453-1646). E-value: 6.1e-57.
                     Score: 184.3. Matches aSDomain:
                     nrpspksdomains_QGU18619.1_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (1734-1816). E-value: 3.7e-15.
                     Score: 47.9. Matches aSDomain:
                     nrpspksdomains_QGU18619.1_PKS_PP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1839-2136). E-value:
                     4.7e-89. Score: 290.2. Matches aSDomain:
                     nrpspksdomains_QGU18619.1_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (2309-2721). E-value:
                     3.2e-97. Score: 317.5. Matches aSDomain:
                     nrpspksdomains_QGU18619.1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (2829-2897). E-value: 1.4e-16.
                     Score: 52.4. Matches aSDomain:
                     nrpspksdomains_QGU18619.1_PCP.1"
                     /NRPS_PKS="Domain: Thioesterase (2917-3119). E-value:
                     6.4e-27. Score: 87.3. Matches aSDomain:
                     nrpspksdomains_QGU18619.1_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 286.2; E-value:
                     7.5e-87)"
                     /gene_kind="biosynthetic"
                     /note="PtmA'; PKS/NRPS"
                     /product="polyketide synthase/non-ribosomal peptide
                     synthetase"
                     /protein_id="QGU18619.1"
                     /sec_met_domain="PKS_KS (E-value: 2.5e-178, bitscore:
                     582.0, seeds: 2284, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 7e-104, bitscore: 336.0,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 8e-52, bitscore:
                     164.4, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 1.9e-69, bitscore:
                     222.7, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.4e-104, bitscore:
                     338.5, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 9.3e-15, bitscore:
                     43.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADAIETNTGALRQKVAIVGMGCRFPGGASDHRTFWRNLMAGKDC
                     ITPTPPDRYDVTTLGSRFRDKPGRLVGGRGGYIDGFDEFDPAFFGISPREADHMDPQQR
                     KLLEVAWETLEDGGQRPADLAGENVAVYVGAFTLDYKILQFADLGFTTLAAHTATGTMM
                     TMVSNRISYCFDFRGPSLSVDTACSSSLVAVHLACQALARGETDLALAGGTLLNLAPQY
                     TIAETKGGFLSTEGRSRTFDAGADGYVRAEGVGLVALKRLEDAVRDGDRIHAVILGSGV
                     NQDGHTNGITVPNPDAQVSLIRRVCAEAGIQPGELQYMEAHGTSTPVGDPIEAKALARA
                     LAIGRRPGSRAYVGSVKTNIGHTESAAGIAGLIKTVLSLKHRHIPPHINLERLNPSIDQ
                     ASLPYEIPTRPTPWPEHDGPARAGVNSFGFGGTNAHVVLEEAPRPAQKTVEETGEETAP
                     PAERAWSILPLSARHPDALPELAAGIHAELAGENGPPVALPDLGHTLAHRRQHLPHRLS
                     VVHTSRASLDEALAAHARGESHPRIVQDRARDAEARRLVWVFTGMGPQWWGMGRQLLRE
                     EPVFREAVTACDRAVREFADWSLIEELTADEPASRMAETWLAQPANFAVQVGLAALWKT
                     YGVRPDAVVGHSTGEIAAFYEAGVYSLRDAARIAVHRSRLQQTLAGTGTMLAVALTEDE
                     AERRVRPYRDRVSIAAVNSPTSLTLAGDADALALLAEELRAEQLFAKFLTVEVPYHSVG
                     MERIKDELLTSLAPLDPRPAQLPLYLTGAEGLARGGELDAAYWWRNVRERVRFRAAVDR
                     LAADGHHVFLEIGPHPVLGHAIRECLETAGASGVTLPSIRRQEDESERFALSLASLHNL
                     GADIDWDVLHPAGRPVTLPPHPFRRDRHWTEPPAVAQVRLGHIDHPLLGRRTDRTEPAW
                     QARLDSESLPYLADHRIQDTVVFPAAGYLEMATQAVLRLTGGTSAALADIDLRKALFLP
                     DSEDRIVEVALSLEDAAFTIASPATGDDGERTVHASGVVRTGRRRRTGPPLDADAIRAR
                     TVRRLEGPECYTALARLGYHYGPAFRAIEEVWIGPGEVLARIRPPATVDAAGHHLHPVL
                     LDACFQALLTPQLLQDPVPGAGIRLPLSLAEVALEPIGDRPLWVHATLRPADADTTLGD
                     LALYGDDGTPLGRIEGFRAADVEKAATAVARTTIDSWLAETVWTECPPLGEEEPLAPGV
                     IAARTHGWLLLADTQGVADAFAALAEARGERCHLVRRGEAYAGAGPDGPYTVDPGSSDD
                     FERLFAELDRDGEPFRGTVLHLWNLDRPALADCDRQTVRDHAGPGSYSLIALARTLLAR
                     GGSGRLHIVTRGAQPVLPDEPVEPLGAPAWGVGRVLRHQELTDHPGKLIDLDPERRPGS
                     EGARAEAEALLREALADDEQEIALRAGVRRTSRLRPAEGLTRPLPPRLRADGSYLVTGA
                     FGALGRLLCRTLVRRGARRIVLMGRTPVPAREKWGSTDPATAEGRAVALLRELEALGAQ
                     AVLAPLDITDEDALTGWLDGYRRAGHPPVRGVFHLAGQVRDTLVTDLDRPAFDAVHDPK
                     TIGAHLLHRHLRDEPLDHFVLFASVASLLTTAGQTNYAAGNAFLDALAHHRRAQGLPAL
                     SLDWGPWATGMIEELGLVDHYLHSRGMSSLAPDAGMAVLERVLGQDHAQLVIATVVDWP
                     TFLAWYPSPPPLVTALAAAAAPPPDTDRGSGFLDTFRTADEEGRRALVAERFAALSAAV
                     LRTGTDRIDPAEGLGQLGLDSLLAMELRARIHAELGVALPVVALLSGTPAGELAAQLHD
                     GLLELASAEDTDATDRAVTLHDDPARYPLTQNQKALWFLKHLNPDGYAYNIGGAVEVNV
                     ALEPDLMFEAVRRLIARHPALRTNFLLEDGQAVQRVSEDVVPDLALHDVQGEEWETIHA
                     TIVAEYRKPYDLAHDPLVRFRLFKRGHDRWIIMKAVHHIVSDAISTFTFIEELFQVYEA
                     LRQGQEPQLPPVEARYLDFLNQQNTFLAGREAAGMLDYWRSHLPAEVPLLDLPTDKPRP
                     AVQTHNGASEFFALDPGLSARVHALARAHHVTPFMVLLSAYYLLLHRYSGQDHIVVGSP
                     VTGRTRQDFASVYGYFVNPLPLHADLTGDPSVADLLEQVRRTVLGGLDNQEYPFVLLVD
                     ELGLQHDPSRSAVFQAMFILLTHKVATEQYGYRLEYIELPEEEGQFDITLSAYEDESDH
                     RFHCVFKYNTDLFLPQTMRRMAAHYTRLLDDMTRVPGEHPASRLEMLDDGEREQLVGEW
                     SRPALPSETTDSPFTPVHALIGEVAAAHPASVAVTMPLPGGGARRLTYAELERRAADTG
                     ARLRTLGVGDGSVVVVRLDKSPELIVTLLAVLKAGGAYLPLRPDQPADRIAHLVRTTGA
                     TVVIVSGEPAREETAALPVITLTLDDLHATEPHPDGPPPDPAPDSTAYVITTSGSTGRP
                     KAVRVSHRNLASAYEAWRQEYRLETDVRTHLQMAEPSFDVFTGDLVRALCSGGSLVLAD
                     RDLLFDTARLYRTMRQERVDCAEFVPAVVRGLMDHCVREGLRLDFLRLLVVGSDAWKVG
                     EYQRLSELCGPATRLVNSYGLTEATIDSACFEGPVDDLEPGLMVPIGRPLPNSTLHILD
                     THGEPVPPGVPGELWIGGDGVAIGYAGEPEQTADRFITRTLSKRPGARPERLYRTGDIA
                     RWDAHGRVHLLGRTDGQVKLRGHRIEIGEIEAHLAQWPPLARAVVTVTTDTGGEAVLCA
                     YCVPAPGAALDRRALRRHLAGALPSYMIPAYFVELPALPLTANGKVDTAALPAPRAETG
                     ERSHEEPVTLYEISVARHWKTLLGLEQVGLEDDFFEIGGSSIKLIELLHLLRTEFGVSV
                     PVSRLYQVTTLHGMAATVQEVLHSTSTDELPSLTFNAGQSPPLFCFPPAGGHGLVYRGL
                     AAQLPEYAVIGFNYLPGDDKVARYADLVETARPEGPCLFLGYSLGGNLAFETAKELERR
                     GRRVGHVVILDSRRIMERYEPGDEGIRHFEAELADHLRKHTGSEAVAQETLAHAAEYLT
                     FCGRTPNTGTVDAPVSVITDQEKAALYAAGQHGTWHGSSTATTVVLRGSGLHADMLDPK
                     HLPRNAALIRTVLTGDAAHGD"
     misc_feature    1715..1717
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     aSDomain        1727..3007
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_QGU18619.1_PKS_KS.1"
                     /domain_subtypes="Hybrid-KS"
                     /evalue="2.30E-177"
                     /label="QGU18619.1_PKS_KS.1"
                     /locus_tag="QGU18619.1"
                     /protein_end="442"
                     /protein_start="15"
                     /score="582.0"
                     /tool="antismash"
                     /translation="VAIVGMGCRFPGGASDHRTFWRNLMAGKDCITPTPPDRYDVTTLG
                     SRFRDKPGRLVGGRGGYIDGFDEFDPAFFGISPREADHMDPQQRKLLEVAWETLEDGGQ
                     RPADLAGENVAVYVGAFTLDYKILQFADLGFTTLAAHTATGTMMTMVSNRISYCFDFRG
                     PSLSVDTACSSSLVAVHLACQALARGETDLALAGGTLLNLAPQYTIAETKGGFLSTEGR
                     SRTFDAGADGYVRAEGVGLVALKRLEDAVRDGDRIHAVILGSGVNQDGHTNGITVPNPD
                     AQVSLIRRVCAEAGIQPGELQYMEAHGTSTPVGDPIEAKALARALAIGRRPGSRAYVGS
                     VKTNIGHTESAAGIAGLIKTVLSLKHRHIPPHINLERLNPSIDQASLPYEIPTRPTPWP
                     EHDGPARAGVNSFGFGGTNAHVVLEEAP"
     aSModule        1727..7129
                     /complete
                     /domains="nrpspksdomains_QGU18619.1_PKS_KS.1"
                     /domains="nrpspksdomains_QGU18619.1_PKS_AT.1"
                     /domains="nrpspksdomains_QGU18619.1_PKS_DH.1"
                     /domains="nrpspksdomains_QGU18619.1_PKS_KR.1"
                     /domains="nrpspksdomains_QGU18619.1_PKS_PP.1"
                     /locus_tags="QGU18619.1"
                     /monomer_pairings="pk -> pk"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       2213..2260
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QGU18619.1_0001"
                     /evalue="2.00E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="QGU18619.1"
                     /protein_end="193"
                     /protein_start="177"
                     /score="19.8"
                     /tool="antismash"
                     /translation="GPSLSVDTACSSSLVA"
     CDS_motif       2402..2440
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QGU18619.1_0002"
                     /evalue="9.70E-04"
                     /label="PKSI-KS_m4"
                     /locus_tag="QGU18619.1"
                     /protein_end="253"
                     /protein_start="240"
                     /score="12.3"
                     /tool="antismash"
                     /translation="FDAGADGYVRAEG"
     CDS_motif       2633..2680
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QGU18619.1_0003"
                     /evalue="2.70E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="QGU18619.1"
                     /protein_end="333"
                     /protein_start="317"
                     /score="10.4"
                     /tool="antismash"
                     /translation="YMEAHGTSTPVGDPIE"
     CDS_motif       2741..2785
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QGU18619.1_0004"
                     /evalue="9.20E-04"
                     /label="PKSI-KS_m6"
                     /locus_tag="QGU18619.1"
                     /protein_end="368"
                     /protein_start="353"
                     /score="11.7"
                     /tool="antismash"
                     /translation="GSVKTNIGHTESAAG"
     CDS_motif       3347..3403
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QGU18619.1_0005"
                     /evalue="3.20E-04"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="QGU18619.1"
                     /protein_end="574"
                     /protein_start="555"
                     /score="13.4"
                     /tool="antismash"
                     /translation="VWVFTGMGPQWWGMGRQLL"
     aSDomain        3353..4240
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_QGU18619.1_PKS_AT.1"
                     /evalue="6.50E-103"
                     /label="QGU18619.1_PKS_AT.1"
                     /locus_tag="QGU18619.1"
                     /protein_end="853"
                     /protein_start="557"
                     /score="336.0"
                     /specificity="substrate consensus: pk"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="VFTGMGPQWWGMGRQLLREEPVFREAVTACDRAVREFADWSLIEE
                     LTADEPASRMAETWLAQPANFAVQVGLAALWKTYGVRPDAVVGHSTGEIAAFYEAGVYS
                     LRDAARIAVHRSRLQQTLAGTGTMLAVALTEDEAERRVRPYRDRVSIAAVNSPTSLTLA
                     GDADALALLAEELRAEQLFAKFLTVEVPYHSVGMERIKDELLTSLAPLDPRPAQLPLYL
                     TGAEGLARGGELDAAYWWRNVRERVRFRAAVDRLAADGHHVFLEIGPHPVLGHAIRECL
                     ETAGASGVTLPSIRR"
     CDS_motif       3533..3583
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QGU18619.1_0006"
                     /evalue="3.40E-04"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="QGU18619.1"
                     /protein_end="634"
                     /protein_start="617"
                     /score="13.8"
                     /tool="antismash"
                     /translation="AQPANFAVQVGLAALWK"
     CDS_motif       3590..3706
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QGU18619.1_0007"
                     /evalue="1.20E-14"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="QGU18619.1"
                     /protein_end="675"
                     /protein_start="636"
                     /score="46.3"
                     /tool="antismash"
                     /translation="GVRPDAVVGHSTGEIAAFYEAGVYSLRDAARIAVHRSRL"
     CDS_motif       4052..4099
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QGU18619.1_0008"
                     /evalue="5.30E-04"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="QGU18619.1"
                     /protein_end="806"
                     /protein_start="790"
                     /score="12.5"
                     /tool="antismash"
                     /translation="LDAAYWWRNVRERVRF"
     aSDomain        4427..4909
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_QGU18619.1_PKS_DH.1"
                     /evalue="1.90E-34"
                     /label="QGU18619.1_PKS_DH.1"
                     /locus_tag="QGU18619.1"
                     /protein_end="1076"
                     /protein_start="915"
                     /score="111.3"
                     /tool="antismash"
                     /translation="HPLLGRRTDRTEPAWQARLDSESLPYLADHRIQDTVVFPAAGYLE
                     MATQAVLRLTGGTSAALADIDLRKALFLPDSEDRIVEVALSLEDAAFTIASPATGDDGE
                     RTVHASGVVRTGRRRRTGPPLDADAIRARTVRRLEGPECYTALARLGYHYGPAFRAI"
     CDS_motif       4502..4579
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QGU18619.1_0009"
                     /evalue="3.40E-13"
                     /label="PKSI-DH_m2"
                     /locus_tag="QGU18619.1"
                     /protein_end="966"
                     /protein_start="940"
                     /score="41.9"
                     /tool="antismash"
                     /translation="YLADHRIQDTVVFPAAGYLEMATQAV"
     aSDomain        6041..6619
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_QGU18619.1_PKS_KR.1"
                     /evalue="6.10E-57"
                     /label="QGU18619.1_PKS_KR.1"
                     /locus_tag="QGU18619.1"
                     /protein_end="1646"
                     /protein_start="1453"
                     /score="184.3"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="GSYLVTGAFGALGRLLCRTLVRRGARRIVLMGRTPVPAREKWGST
                     DPATAEGRAVALLRELEALGAQAVLAPLDITDEDALTGWLDGYRRAGHPPVRGVFHLAG
                     QVRDTLVTDLDRPAFDAVHDPKTIGAHLLHRHLRDEPLDHFVLFASVASLLTTAGQTNY
                     AAGNAFLDALAHHRRAQGLPALSLDWGPWA"
     CDS_motif       6044..6142
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QGU18619.1_0010"
                     /evalue="2.40E-13"
                     /label="PKSI-KR_m1"
                     /locus_tag="QGU18619.1"
                     /protein_end="1487"
                     /protein_start="1454"
                     /score="42.6"
                     /tool="antismash"
                     /translation="SYLVTGAFGALGRLLCRTLVRRGARRIVLMGRT"
     CDS_motif       6464..6574
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QGU18619.1_0011"
                     /evalue="1.10E-20"
                     /label="PKSI-KR_m4"
                     /locus_tag="QGU18619.1"
                     /protein_end="1631"
                     /protein_start="1594"
                     /score="66.2"
                     /tool="antismash"
                     /translation="LDHFVLFASVASLLTTAGQTNYAAGNAFLDALAHHRR"
     aSDomain        6884..7129
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_QGU18619.1_PKS_PP.1"
                     /evalue="3.70E-15"
                     /label="QGU18619.1_PKS_PP.1"
                     /locus_tag="QGU18619.1"
                     /protein_end="1816"
                     /protein_start="1734"
                     /score="47.9"
                     /tool="antismash"
                     /translation="TADEEGRRALVAERFAALSAAVLRTGTDRIDPAEGLGQLGLDSLL
                     AMELRARIHAELGVALPVVALLSGTPAGELAAQLHDG"
     CDS_motif       7094..7150
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QGU18619.1_0012"
                     /evalue="2.00E+01"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="QGU18619.1"
                     /protein_end="1823"
                     /protein_start="1804"
                     /score="-1.4"
                     /tool="antismash"
                     /translation="PAGELAAQLHDGLLELASA"
     aSDomain        7199..8089
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_QGU18619.1_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="4.70E-89"
                     /label="QGU18619.1_Condensation_LCL.1"
                     /locus_tag="QGU18619.1"
                     /protein_end="2136"
                     /protein_start="1839"
                     /score="290.2"
                     /tool="antismash"
                     /translation="ARYPLTQNQKALWFLKHLNPDGYAYNIGGAVEVNVALEPDLMFEA
                     VRRLIARHPALRTNFLLEDGQAVQRVSEDVVPDLALHDVQGEEWETIHATIVAEYRKPY
                     DLAHDPLVRFRLFKRGHDRWIIMKAVHHIVSDAISTFTFIEELFQVYEALRQGQEPQLP
                     PVEARYLDFLNQQNTFLAGREAAGMLDYWRSHLPAEVPLLDLPTDKPRPAVQTHNGASE
                     FFALDPGLSARVHALARAHHVTPFMVLLSAYYLLLHRYSGQDHIVVGSPVTGRTRQDFA
                     SVYGYFVNPLPLHADL"
     aSModule        7199..11038
                     /complete
                     /domains="nrpspksdomains_QGU18619.1_Condensation_LCL.1"
                     /domains="nrpspksdomains_QGU18619.1_AMP-binding.1"
                     /domains="nrpspksdomains_QGU18619.1_PCP.1"
                     /domains="nrpspksdomains_QGU18619.1_Thioesterase.1"
                     /final_module
                     /locus_tags="QGU18619.1"
                     /monomer_pairings="Orn -> Orn"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       7268..7378
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QGU18619.1_0013"
                     /evalue="1.60E-09"
                     /label="C2_LCL_024-062"
                     /locus_tag="QGU18619.1"
                     /protein_end="1899"
                     /protein_start="1862"
                     /score="30.2"
                     /tool="antismash"
                     /translation="AYNIGGAVEVNVALEPDLMFEAVRRLIARHPALRTNF"
     CDS_motif       7586..7651
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QGU18619.1_0014"
                     /evalue="2.60E-06"
                     /label="C3_DCL_135-156"
                     /locus_tag="QGU18619.1"
                     /protein_end="1990"
                     /protein_start="1968"
                     /score="20.0"
                     /tool="antismash"
                     /translation="VHHIVSDAISTFTFIEELFQVY"
     CDS_motif       7994..8077
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QGU18619.1_0015"
                     /evalue="1.00E-10"
                     /label="C5_LCL_267-296"
                     /locus_tag="QGU18619.1"
                     /protein_end="2132"
                     /protein_start="2104"
                     /score="34.0"
                     /tool="antismash"
                     /translation="IVVGSPVTGRTRQDFASVYGYFVNPLPL"
     CDS_motif       8129..8248
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QGU18619.1_0016"
                     /evalue="1.30E-15"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="QGU18619.1"
                     /protein_end="2189"
                     /protein_start="2149"
                     /score="49.6"
                     /tool="antismash"
                     /translation="RRTVLGGLDNQEYPFVLLVDELGLQHDPSRSAVFQAMFIL"
     aSDomain        8609..9844
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_QGU18619.1_AMP-binding.1"
                     /evalue="3.20E-97"
                     /label="QGU18619.1_AMP-binding.1"
                     /locus_tag="QGU18619.1"
                     /protein_end="2721"
                     /protein_start="2309"
                     /score="317.5"
                     /specificity="substrate consensus: Orn"
                     /tool="antismash"
                     /translation="EVAAAHPASVAVTMPLPGGGARRLTYAELERRAADTGARLRTLGV
                     GDGSVVVVRLDKSPELIVTLLAVLKAGGAYLPLRPDQPADRIAHLVRTTGATVVIVSGE
                     PAREETAALPVITLTLDDLHATEPHPDGPPPDPAPDSTAYVITTSGSTGRPKAVRVSHR
                     NLASAYEAWRQEYRLETDVRTHLQMAEPSFDVFTGDLVRALCSGGSLVLADRDLLFDTA
                     RLYRTMRQERVDCAEFVPAVVRGLMDHCVREGLRLDFLRLLVVGSDAWKVGEYQRLSEL
                     CGPATRLVNSYGLTEATIDSACFEGPVDDLEPGLMVPIGRPLPNSTLHILDTHGEPVPP
                     GVPGELWIGGDGVAIGYAGEPEQTADRFITRTLSKRPGARPERLYRTGDIARWDAHGRV
                     HLLGRTDGQVKLR"
     CDS_motif       8804..8842
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QGU18619.1_0017"
                     /evalue="1.60E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="QGU18619.1"
                     /protein_end="2387"
                     /protein_start="2374"
                     /score="15.0"
                     /tool="antismash"
                     /translation="LAVLKAGGAYLPL"
     CDS_motif       9035..9094
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QGU18619.1_0018"
                     /evalue="1.10E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="QGU18619.1"
                     /protein_end="2471"
                     /protein_start="2451"
                     /score="24.2"
                     /tool="antismash"
                     /translation="AYVITTSGSTGRPKAVRVSH"
     CDS_motif       9623..9712
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QGU18619.1_0019"
                     /evalue="5.00E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="QGU18619.1"
                     /protein_end="2677"
                     /protein_start="2647"
                     /score="44.4"
                     /tool="antismash"
                     /translation="PPGVPGELWIGGDGVAIGYAGEPEQTADRF"
     CDS_motif       9812..9874
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QGU18619.1_0020"
                     /evalue="1.60E-09"
                     /label="NRPS-A_a8"
                     /locus_tag="QGU18619.1"
                     /protein_end="2731"
                     /protein_start="2710"
                     /score="29.9"
                     /tool="antismash"
                     /translation="LGRTDGQVKLRGHRIEIGEIE"
     aSDomain        10169..10372
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_QGU18619.1_PCP.1"
                     /evalue="1.40E-16"
                     /label="QGU18619.1_PCP.1"
                     /locus_tag="QGU18619.1"
                     /protein_end="2897"
                     /protein_start="2829"
                     /score="52.4"
                     /tool="antismash"
                     /translation="EISVARHWKTLLGLEQVGLEDDFFEIGGSSIKLIELLHLLRTEFG
                     VSVPVSRLYQVTTLHGMAATVQE"
     aSDomain        10433..11038
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_QGU18619.1_Thioesterase.1"
                     /evalue="6.40E-27"
                     /label="QGU18619.1_Thioesterase.1"
                     /locus_tag="QGU18619.1"
                     /protein_end="3119"
                     /protein_start="2917"
                     /score="87.3"
                     /tool="antismash"
                     /translation="PPLFCFPPAGGHGLVYRGLAAQLPEYAVIGFNYLPGDDKVARYAD
                     LVETARPEGPCLFLGYSLGGNLAFETAKELERRGRRVGHVVILDSRRIMERYEPGDEGI
                     RHFEAELADHLRKHTGSEAVAQETLAHAAEYLTFCGRTPNTGTVDAPVSVITDQEKAAL
                     YAAGQHGTWHGSSTATTVVLRGSGLHADMLDPKHLPRNA"
     CDS_motif       10436..10465
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QGU18619.1_0021"
                     /evalue="1.40E-02"
                     /label="NRPS-beforete1"
                     /locus_tag="QGU18619.1"
                     /protein_end="2928"
                     /protein_start="2918"
                     /score="8.6"
                     /tool="antismash"
                     /translation="PLFCFPPAGG"
     CDS_motif       10586..10657
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QGU18619.1_0022"
                     /evalue="8.40E-10"
                     /label="NRPS-te1"
                     /locus_tag="QGU18619.1"
                     /protein_end="2992"
                     /protein_start="2968"
                     /score="31.0"
                     /tool="antismash"
                     /translation="PEGPCLFLGYSLGGNLAFETAKEL"
     CDS_motif       10802..10858
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QGU18619.1_0023"
                     /evalue="3.10E+01"
                     /label="PKSI-KR_m1"
                     /locus_tag="QGU18619.1"
                     /protein_end="3059"
                     /protein_start="3040"
                     /score="-2.6"
                     /tool="antismash"
                     /translation="VAQETLAHAAEYLTFCGRT"
     CDS             11076..12776
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222:dehydrogenase (Score: 333.1; E-value: 5.7e-101)"
                     /gene_kind="biosynthetic-additional"
                     /note="PtmB1'"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="QGU18620.1"
                     /transl_table=11
                     /translation="MATDTTLRKETVDDWGSRERTPGTPPRVIVIGAGVAGLSTGCYAQ
                     MSGARTRIFEKHVLPGGCCTAWSRDGYLFDYCIEWLIGTAPGNDAHQVWRELGALDGKT
                     VTNFELFNKVEDERGRSVTFYNDPDRLEAHLLALSPADAPLIRAFTRDLRRFIDIELYP
                     FLTAPALRTVRERAATLRTVLPAFRLFWRTAATPMHVFADKFQDPLLRRAFRNIFFQDP
                     EGFPLLPYLFNMAAAHHLNAGFPQGGSLGLSRSVENRYLGLGGEVTYRARTEKILVEND
                     RAIGIELRNGRRYFAEHIVSACDGRTTVHGLLDGRYTSPRIDKLYNDLIERPGTLFPAV
                     VSAFVGLRGDFDPGEAHSTTHLLTDEDGRRLPGALQNSLVVQARSRYSDGFAPPGRSVL
                     HCTYFSDYAYWKELRTRSRREYRGRKHEVADFVRTFLEHRHPGINDRIDLVDIASPATT
                     HRYTGNHNGSILAWKAFSDADDVAARLVGKDRMRLPGLSGFSMAGQWVGMGGLIRAAST
                     GRFAVQYLCRELGLEFRAWESEGTEPWHPGMLGELPQLDRWSAREDTGS"
     CDS             12773..14497
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222:dehydrogenase (Score: 564.6; E-value: 3.7e-171)"
                     /gene_kind="biosynthetic-additional"
                     /note="PtmB2'"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="QGU18621.1"
                     /transl_table=11
                     /translation="MTHRTTGSPREPRESMIIIGGGLGGLSTGCYARMNGYRTRILEMH
                     ELPGGCCTAWERGGFTLDACVSWLLGSGPGNEMHQIWLELGALQGKEIRHFDVFNIVRG
                     QDGRAVHFYSDPDRLEAHLIAISPADARTVRKFCNQLRSFRKALAVYPFLKPVGLMGRL
                     ERWRMLASFVPYFNAVRTTITVLMTEYSAKFQDPLLREAFNFILYEKHPNFPVLPFHFQ
                     LASHANLSAGVPEGGSLGLARSIEARYRRLGGEISYNTKVETVIVEDDRAVGVRLSDGS
                     ELRADIVVSACDGYTTTMKFLKGAYLGEEYRKLYTETIHEPGMVFPGYFTLFLGLSRPF
                     PEGDPCTTYLLDEATAAKLTGIRHASINVQFRSRHYPELSPDGTTVVYATYFCDIAPWR
                     ALDEGPEQVTRTRGGQELHTLPVRHGRGYYAAKRRARETLVEFLEERFPGIRDAIVVRD
                     VSSPLTQVRYTGNYDGTVLGWQPFVESGEKLEELIKKHGPGLPGLANFYQSGVWATTGG
                     LIRAAAAGRHVMQFICRDDGKPFTASLDRAAPPPTHRVIPVPTGRSTAAATTTGKGT"
     CDS             14494..15549
                     /NRPS_PKS="Domain: PKS_ER (141-250). E-value: 1.5e-12.
                     Score: 39.2. Matches aSDomain:
                     nrpspksdomains_QGU18622.1_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028:crotonyl-CoA reductase / alcohol dehydrogenase
                     (Score: 91.1; E-value: 1.2e-27)"
                     /gene_kind="biosynthetic-additional"
                     /note="PtmC'"
                     /product="alcohol dehydrogenase"
                     /protein_id="QGU18622.1"
                     /sec_met_domain="ADH_zinc_N (E-value: 8.8e-17, bitscore:
                     50.1, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIEKWVVREHVEGVPDVDRVYEKVVENVDVTLAPDEMLLRTLYV
                     SVDPYLQGIALDTPIGSHMGADSIMEVVAAGPRAAHGVGDLVQGFGGWRSHVVSTGAAE
                     LWQTGTFPMVFPAYRRLDPGWYDDALPLATALSVMGGPGMTAWGTLAKYMTVKPGDTFV
                     ISGASGAVGALVGQLAALAGARVVGTTSSPQKAEYLLGLGFDTVVVYRHTDGADTVREA
                     LTRAAPDGVDRYFDNLGGTVTDVVFSMLNVGSQVAVCWQWATQVGNEETGPRLLPYLMF
                     PRATVRGIFSLEWFTEQNWKDLHADLGSRVRRGEVVCDHTLHHGFDAIPAAYRSLYGDR
                     AESRGKVLVAL"
     aSDomain        14917..15243
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_QGU18622.1_PKS_ER.1"
                     /evalue="1.50E-12"
                     /label="QGU18622.1_PKS_ER.1"
                     /locus_tag="QGU18622.1"
                     /protein_end="250"
                     /protein_start="141"
                     /score="39.2"
                     /tool="antismash"
                     /translation="PGMTAWGTLAKYMTVKPGDTFVISGASGAVGALVGQLAALAGARV
                     VGTTSSPQKAEYLLGLGFDTVVVYRHTDGADTVREALTRAAPDGVDRYFDNLGGTVTDV
                     VFSML"
     CDS             15599..16780
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007:cytochrome P450 (Score: 362.5; E-value:
                     4.3e-110)"
                     /gene_kind="biosynthetic-additional"
                     /note="PtmE"
                     /product="cytochrome P450"
                     /protein_id="QGU18623.1"
                     /sec_met_domain="p450 (E-value: 3.2e-11, bitscore: 31.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAITDPSLIPLHRLRFEEPGPPRPGELPTGVPAWLVSRYADVRQV
                     LSDPRFGRSRLYAEDAPALSDVPDLVNNPDLMFNQDGPDHLRLRRTLRRAFTPRAVARW
                     RPWIAAIVDELLDRLEERPQPADVVEEFTLPLPVAVISRLMGLDGSAWDRMRHWSEHAF
                     SDGSHAGEEVESVLKEFSAFGADLLATRRHTPGDDLVSGLVRAADEEGGVPEAQLVSLV
                     CGLVVGGHDSTMTMLGNGLLYLLGERPESWPRIGADEEAAGRVADRLIHLVPLGDDRGT
                     ARHAAADIEVGGVTIPAGAIVLADCGAANRDPDVFPRHTLDDLFAPLEAPTLSLGAGAH
                     YCLGAWLARTELQLALHRLAARFPELRLAEPVERVTWRTGTTSRSPRRLTVSW"
ORIGIN
        1 gaactgcgcg cgcactgtgc tgacgtcgta cgtcaaggag actccctcgc tcggggcgcc
       61 cgggccgggt cacggtcgtg gcgccgacag ttgcctcacc gcgactccgc cccggggcgg
      121 gtgcgcggtt cggcgccgat catcgcaggg cggacccacc cgggaaaggg ctccgcgcgc
      181 tggtgtatgc gcgggcgcac cgcccccggc ccgcagggcg tagcctctgc cgaccgcgca
      241 tggccccacc cggtcacgct ccttcgcgta cgggcgggct tcccggcgca ttcgcgcgcg
      301 ccggtcccgt gacacaggga tgatcctatg agggaattcc tcatataaat ttacccacca
      361 atgcttcgta agggatttct cgcattccgc tttcaacatc ggtggtgcgc ccggcaattc
      421 ggcgtcgagg tggtggttaa aggtcccgga atcggaaatg aatgatctgg gccgatggag
      481 ctgggggatc ggttcacgcc atggcccgat tccttcggag ccgggtgtcc gcaaagttcg
      541 gtgcatgagc ctccgctcac gccccggggt gtccaccacc ccctcgggcg cccttgaact
      601 gcaccgatgc gatgcgagcg gtgctctttt ccagatcaca tcacctgtgg ggggtcacgg
      661 atggacgagt acggacggtc cgccgatggc gagatcgatt cggttggcca tgcgggcaga
      721 ggaaatccca ggaacggctg gaatggcgag aaaggtgcgg tcgacgcggt gggaatcatc
      781 gcggcccgtg tccttcgtgt ggtcgcctac ccgctgctcc tgctggctgt tgtctcggta
      841 ggtgcggccg ctctggttct gcgctgggat ccggccatcg tgagcccgct tttcctcatc
      901 gggaccctga tgtatctggc ccttctcgaa cagctgattc cctatgagcg gagctggcac
      961 ccgggaaagg acgagtggcg ctggtacggc gtctactttc tgctcaccat ggccggaagc
     1021 ggactggcgc aacttctggt cacggcggcg gtgggctgga tcgcggccga cgagcgcagc
     1081 caccatctct gggccgagat ccccggcgcc ctgctggccg gatcgctcgt cagctatctg
     1141 gtgcaccggc tcggccacac cagcgccctc ctgtggcggc tgcacggagt ccaccacgtc
     1201 ccgcagaagg tcaatgtcgc caacaacggc gtcaaccacg tgctggacat cgtgctcgcc
     1261 cagagcctcg tccagctgac cctggccctg gccggattct cccgctcggc cgtgctggtg
     1321 accgggctct tcgtcgtcgc ccagggctac ttcgtccacg ccaacatcga cgtccgcatc
     1381 ggccggttca accatctgct ggccagcccc gaacagcacc gcctgcacca cagcaccgac
     1441 ctgtccgaag ccggccacta cggctccgac ctctcgtgct gggaccacct cttcggcagc
     1501 ttcacctggc atcccggacg cgaaccggcc gccgtgggcc tccacgaccc ggcctccttc
     1561 cccgccaccg gggagatcgt cgccagcacc ctgcacccgt ggcggcgccg cccgccaccg
     1621 ggcgacccgg ccggaccgga tgccaacccc cgaagctcca ccaccacgtg aggagtcaga
     1681 catggccgac gcgatcgaga cgaacaccgg cgcgttacgt cagaaggtgg cgatcgtcgg
     1741 tatgggctgc cgcttccccg gcggagcctc ggaccaccgg acgttctggc ggaacctgat
     1801 ggcgggcaag gactgcatca cgcccacccc gcccgaccgg tacgacgtca ccacactcgg
     1861 cagccggttc cgtgacaaac ccggccgcct cgtcggcggc cgcgggggat acatcgacgg
     1921 cttcgacgag ttcgaccccg ccttcttcgg tatcagcccc cgtgaggccg accacatgga
     1981 cccccagcag cggaagctgc tggaggtcgc ctgggagacc ctggaggacg gcggccagcg
     2041 ccccgccgac ctggccgggg agaacgtcgc cgtctacgtc ggcgcgttca ccctggacta
     2101 caagatcctc cagttcgcgg acctgggctt caccacgctg gccgcgcaca ccgcgaccgg
     2161 caccatgatg acgatggtgt cgaaccgcat ctcgtactgc ttcgacttcc gcggccccag
     2221 cctctccgtc gacaccgcgt gcagctcctc cctggtcgcc gtccacctcg cctgccaggc
     2281 gctggccagg ggcgagaccg acctcgcgct ggccggcggc accctgctca acctggcccc
     2341 ccagtacacg atcgccgaga cgaagggcgg cttcctctcg accgagggcc gctcccgtac
     2401 gttcgacgcg ggcgccgacg gctatgtacg ggccgagggc gtcggcctgg tggcgctgaa
     2461 gcggctggag gacgccgtcc gagacgggga tcgcatccac gccgtgatcc tcggcagcgg
     2521 ggtcaaccag gacggccaca ccaacggcat caccgtgccc aaccccgacg cgcaggtctc
     2581 cctcatccgc cgcgtctgcg ccgaggcggg catccagccc ggcgaactcc agtacatgga
     2641 ggcccacggc acctccaccc cggtcgggga cccgatcgag gccaaggccc tggcccgcgc
     2701 cctggccatc ggacgccggc cgggcagccg cgcgtacgtc ggctccgtga agaccaacat
     2761 cggccacacc gagtccgccg ccgggatcgc cgggctgatc aagaccgtcc tgagcctgaa
     2821 gcaccgccac atcccgcccc acatcaacct ggagcgcctc aacccctcca tcgaccaggc
     2881 ctccctgccg tacgagatcc ccacccggcc caccccctgg cccgagcacg acgggcccgc
     2941 ccgggcgggc gtcaactcct tcgggttcgg cgggaccaac gcccatgtcg tcctggagga
     3001 ggccccgcgg cccgcgcaga agaccgtgga ggaaaccggg gaggagaccg cccctcccgc
     3061 cgaacgggcc tggagcatcc tgccgctcag cgcccggcac cccgacgccc tcccggagct
     3121 ggccgccggg atccacgccg agctggccgg ggagaacggg ccgcccgtgg ccctgcccga
     3181 cctcggccac accctggccc accgccgcca gcacctcccg caccggctct ccgtcgtcca
     3241 cacctcccgc gcctccctcg acgaggcgct cgccgcccac gcgcgcggcg agagccaccc
     3301 ccggatcgtc caggaccgcg cgcgggacgc cgaagcgcgc cgcctggtct gggtcttcac
     3361 cggcatgggc ccccagtggt gggggatggg ccgccaactc ctgcgcgagg agcccgtctt
     3421 cagggaagcc gtcaccgcct gcgaccgcgc cgtccgggag ttcgccgact ggtccctgat
     3481 cgaggagctg accgccgacg agcccgcctc ccgcatggcc gagacctggc tcgcgcagcc
     3541 cgccaacttc gccgtacagg tcggtctcgc cgccctgtgg aagacgtacg gcgtgcgccc
     3601 ggacgccgtc gtcggccaca gcaccggcga gatcgccgcc ttctacgaag cgggcgtcta
     3661 ctccctccgt gacgccgccc ggatcgccgt gcaccgcagc cgcctccagc agaccctggc
     3721 cgggacgggc accatgctcg cggtggcgct cacggaggac gaggcggagc gccgcgtacg
     3781 cccctaccgg gaccgggtct cgatcgccgc cgtcaacagc ccgacctccc tcacgctggc
     3841 cggggacgcg gacgccctgg ccctgctggc cgaggagctg cgggccgagc agctcttcgc
     3901 caagttcctc accgtggaag tcccgtacca cagtgtcggg atggagcgga tcaaggacga
     3961 actgctcacg tcactggccc ccttggaccc ccgccccgcc caactcccgc tctacctcac
     4021 cggtgccgaa ggtctggccc ggggcggtga gctggacgcc gcctactggt ggcggaacgt
     4081 acgggaacgg gtgcggttcc gggccgccgt cgaccggctc gccgccgacg gccaccacgt
     4141 cttcctggag atcggcccgc accccgtcct cggccacgcc atccgcgagt gcctggagac
     4201 cgccggggcg tccggggtga cgctgccctc gatccgccga caggaggacg agagcgagcg
     4261 gttcgcgctc tccctcgcct cgctccacaa cctgggcgcc gacatcgact gggacgtcct
     4321 ccaccccgcc gggcggcccg tcaccctgcc cccgcacccc ttccgacgcg accggcactg
     4381 gaccgaaccc ccggctgtcg cacaggtccg cctcggccac atcgaccacc cgctcctcgg
     4441 ccgccgcacc gaccgcaccg aaccggcctg gcaggcccgc ctggacagcg agtccctgcc
     4501 ctacctggcc gaccaccgca tccaggacac cgtggtgttc cccgcggccg gttacctcga
     4561 gatggcgacc caggccgtcc tgcggctcac cggcgggacc tccgccgccc tcgccgacat
     4621 cgacctgcgc aaggccctct tcctcccgga cagcgaggac cggatcgtgg aggtggccct
     4681 ctccctggag gacgcggcct tcaccatcgc ctcgcccgcc accggggacg acggcgagcg
     4741 gaccgtccac gcgagcgggg tcgtccgcac cggccggcgc cgcaggaccg gcccaccgct
     4801 cgacgccgac gcgatccgcg cccgtacggt ccgccgcctc gaaggccccg agtgctacac
     4861 cgcactggcc cggctcggct accactacgg acccgccttc cgggccatcg aggaggtgtg
     4921 gatcggcccc ggagaggtcc tcgcccggat ccgcccgccc gcgacggtcg acgccgccgg
     4981 ccaccacctc cacccggtcc tcctcgacgc ctgcttccag gcgctgctga ccccgcagct
     5041 cctccaggac ccggtacccg gcgcgggcat caggctgccg ctctcgctgg ccgaggtcgc
     5101 cctcgaaccg atcggggacc ggccgctctg ggtgcacgcc accctgcgcc ccgccgacgc
     5161 cgacaccacc ctcggagacc tcgcgctcta cggggacgac ggcacaccgc tcggccggat
     5221 cgaggggttc cgggccgccg acgtggagaa ggcggccacc gccgtcgccc gcaccaccat
     5281 cgactcctgg ctcgcggaga ccgtctggac ggagtgcccg ccgctcgggg aggaggaacc
     5341 gctcgcgccc ggcgtcatag cggcccgcac ccacggctgg ctgctgctgg ccgacaccca
     5401 gggcgtcgcg gacgccttcg ccgccctcgc cgaggcccgg ggcgaacgct gccacctggt
     5461 gcgccggggc gaggcgtacg ccggagcggg gccggacggc ccgtacacgg tcgaccccgg
     5521 ctcctccgac gacttcgagc gcctcttcgc ggagctggac cgggacggtg aaccgttccg
     5581 gggcaccgtc ctgcacctgt ggaacctgga ccgacccgcg ctcgccgact gcgaccggca
     5641 gaccgtacgg gaccacgcgg gccccggctc gtactccctg atcgccctgg cccgcaccct
     5701 gctcgcccgg ggcggaagcg gccggctgca catcgtcacc cggggcgccc agcccgtcct
     5761 gcccgacgag cccgtcgaac ccctgggggc acccgcttgg ggcgtcggcc gggtcctgcg
     5821 ccaccaggag ctgaccgacc accccggcaa gctgatcgat ctcgaccccg agcggcggcc
     5881 gggatccgaa ggggccaggg ccgaggccga ggcgctcctg cgcgaggcac tggccgatga
     5941 cgagcaggag atcgccctgc gcgcgggcgt acgccgcacc agccgtctcc gccccgccga
     6001 aggcctgacc cggcccctgc cgccccggct gcgggccgac ggcagctatc tggtgaccgg
     6061 cgccttcggg gcgctcggcc gactcctctg ccgcaccctc gtccggcgcg gggcgcgcag
     6121 gatcgtcctg atggggcgta cgccggtgcc cgcccgggag aagtggggct ccaccgaccc
     6181 cgccaccgcc gagggccgcg cggtggccct cctccgcgag ttggaggcgc tcggcgccca
     6241 ggccgtcctg gccccgctcg acatcaccga cgaggacgcc ctgaccggct ggctggacgg
     6301 ctaccggcgc gccggacacc cacccgtacg cggggtgttc cacctcgccg gacaggtccg
     6361 cgacaccctc gtcaccgacc tggaccggcc cgccttcgac gccgtccacg accccaagac
     6421 catcggcgcc cacctcctcc accggcacct gcgcgacgaa ccgctcgacc acttcgtcct
     6481 cttcgcctcg gtcgcctccc tgctgaccac cgccggacag accaactacg cggcgggcaa
     6541 cgccttcctg gacgccctcg cccaccaccg ccgggcccag gggctgcccg cgctcagcct
     6601 ggactggggc ccctgggcca ccggcatgat cgaggaactc ggcctggtcg accactacct
     6661 gcacagccgc gggatgagct ccctcgcccc cgacgccggg atggccgtcc tcgaacgcgt
     6721 cctcggccag gaccacgccc aactggtcat cgccaccgtc gtcgactggc cgaccttcct
     6781 ggcctggtat ccctcaccgc ccccgctcgt caccgccctc gccgcggccg ccgccccgcc
     6841 cccggacacc gaccggggca gcggcttcct cgacaccttc cgcaccgccg acgaggaggg
     6901 gcgccgcgcc ctggtggccg aacgcttcgc cgcactctcc gccgccgtcc tgcgcactgg
     6961 cacggaccgc atcgaccccg ccgaaggcct cggccaactg ggcctggact cgctgctggc
     7021 gatggagcta cgggcccgca tccacgccga actcggcgtc gccctgcccg tggtcgccct
     7081 cctcagcggc accccggccg gagaactggc cgcacagctc cacgacggcc tgctggagct
     7141 ggcctcggcc gaggacaccg acgccacgga ccgggccgtc accctccacg acgacccggc
     7201 ccgctacccg ctcacccaga accagaaggc gctctggttc ctcaagcacc tcaaccccga
     7261 cgggtacgcc tacaacatcg gcggggccgt cgaggtgaac gtcgccctcg aaccggacct
     7321 gatgttcgag gccgtacgcc gcctcatcgc ccgccacccc gccctgcgca ccaacttcct
     7381 gctggaggac gggcaggccg tgcagcgggt ctccgaggac gtggtgcccg acctcgccct
     7441 ccatgacgtc cagggcgagg agtgggagac catccacgcc accatcgtcg ccgagtaccg
     7501 caagccctac gacctcgccc acgacccgct ggtccgcttc cggctcttca agcgcggcca
     7561 cgaccgctgg atcatcatga aggccgtcca ccacatcgtc tccgacgcca tctccacctt
     7621 caccttcatc gaggaactct tccaggtcta cgaagcactg cggcagggac aggaacccca
     7681 actgcccccg gtcgaagccc gctacctgga cttcctcaac cagcagaaca ccttcctcgc
     7741 cgggcgtgag gccgccggaa tgctcgacta ctggcgctcc cacctccccg ccgaggtccc
     7801 gctcctggac ctccccaccg acaaaccccg cccggccgtc cagacccaca acggggcctc
     7861 cgagttcttc gcgctcgacc ccggactcag cgcccgcgtc cacgccctgg cccgcgccca
     7921 ccacgtcacc ccgttcatgg tgctgctcag cgcctactac ctgctgctcc accgctactc
     7981 gggccaggac cacatcgtcg tcggttcccc ggtgaccggc cgcacccgcc aggacttcgc
     8041 ctccgtctac ggctacttcg tcaacccgct cccgctccac gccgacctca ccggcgaccc
     8101 gagcgtggcg gacctcctgg agcaggtccg ccggaccgtc ctcggcggac tggacaacca
     8161 ggagtacccg ttcgtcctgc tcgtcgacga actggggctc cagcacgacc ccagccgctc
     8221 ggccgtcttc caggcgatgt tcatcctcct cacccacaag gtcgccaccg agcagtacgg
     8281 ctaccggctg gagtacatcg aactaccgga ggaggagggt cagttcgaca tcaccctctc
     8341 cgcctacgag gacgagtcgg accaccgctt ccactgcgtc ttcaagtaca acaccgacct
     8401 cttcctcccg cagaccatgc gccgcatggc cgcccactac acccgcctgc tcgacgacat
     8461 gacccgggtg cccggcgaac accccgcgtc ccggctggag atgctcgacg acggcgaacg
     8521 cgaacagctc gtgggggagt ggagccgccc cgccctgccg tcggagacca cggattcccc
     8581 cttcacgccg gtccacgcgc tgatcggcga ggtcgccgcc gcccaccccg cctccgtcgc
     8641 cgtgaccatg ccgctcccgg gcggcggagc acgccgcctc acctacgcgg agctggagcg
     8701 gcgggccgcc gacacgggcg cccggctgcg caccctgggt gtcggggacg gctcggtggt
     8761 cgtcgtccgc ctggacaagt cgcccgagct gatcgtcacc ctgctcgccg tgctgaaggc
     8821 cggcggcgcc tatctgccgc tccgccccga ccagcccgcc gaccgcatcg cccacctcgt
     8881 ccggaccacc ggagccaccg tcgtcatcgt ctccggcgaa cccgcgcgcg aggagacggc
     8941 ggcgctcccg gtcatcaccc tcaccctcga cgacctgcac gccaccgagc cgcaccccga
     9001 cgggcccccg ccggacccgg ccccggactc gaccgcgtac gtcatcacca cctccggctc
     9061 caccggccgt cccaaggccg tccgcgtcag ccaccgcaac ctcgcctccg cctacgaggc
     9121 ctggcgccag gagtaccgtc tggagacgga cgtccggaca cacctccaga tggccgagcc
     9181 gtcgttcgac gtgttcaccg gcgacctggt ccgcgcgctc tgctccggcg gcagcctcgt
     9241 cctggccgac cgggacctgc tcttcgacac cgcccggctc taccggacga tgcgtcagga
     9301 gcgggtcgac tgtgcggagt tcgtcccggc cgtcgtgcgc ggtctgatgg accactgtgt
     9361 acgggagggg ctgcggctgg acttcctgcg gctgctggtg gtcggctcgg acgcctggaa
     9421 ggtgggggag taccagcggc tgagcgagct gtgcggcccg gcgacccggc tcgtcaactc
     9481 ctacggcctc accgaggcca ccatcgacag cgcctgcttc gaaggccccg tcgacgacct
     9541 ggaacccggc ctcatggtcc ccatcggccg ccctctcccg aacagcaccc tgcacatcct
     9601 ggacacccac ggcgaacccg tcccgcccgg cgtccccggc gaactgtgga tcggcggcga
     9661 cggcgtcgcc atcggctacg cgggagagcc cgagcagacg gccgaccgct tcatcacccg
     9721 tacgctgagc aaacggcccg gcgcccggcc cgaacggctc taccggaccg gcgacatcgc
     9781 ccgctgggac gcccacggcc gcgtccatct gctcggccgc accgacggcc aggtcaaact
     9841 gcgcggccac cgcatcgaga tcggcgagat cgaggcccac ctcgcccagt ggcccccgct
     9901 cgcccgcgcc gtcgtcaccg tcaccacgga caccggggga gaggccgtgc tctgcgccta
     9961 ctgcgtaccg gcacccggcg ccgcactcga ccgccgggcc ctgcgccgcc acctggccgg
    10021 ggcgctcccc tcgtacatga tcccggcgta cttcgtcgaa ctgcccgccc tgccgctcac
    10081 cgccaacggc aaggtcgaca ccgccgccct gcccgcaccc cgggccgaga ccggtgaacg
    10141 gagccacgag gagccggtga cgctctacga gatcagcgtg gcccggcact ggaagaccct
    10201 cctcggcctc gaacaggtgg gcctggagga cgacttcttc gagatcggcg gctcctccat
    10261 caagctcatc gagctgctcc acctgctgcg caccgagttc ggtgtcagcg tccccgtcag
    10321 ccgcctctac caggtcacca ccctccacgg catggccgcc accgtccagg aggtcctgca
    10381 cagcaccagc accgacgaac tgccctccct caccttcaac gccggccagt caccgcccct
    10441 cttctgcttc ccgcccgcgg gcggccacgg actcgtctac cgggggctgg ccgcccagct
    10501 ccccgagtac gccgtcatcg gcttcaacta cctcccgggc gacgacaagg tggcccgcta
    10561 cgccgacctc gtcgagaccg cccgccccga aggcccctgc ctgttcctcg gctactccct
    10621 cggcggcaac ctggccttcg agaccgccaa ggagctggag cggcgcggac ggcgggtggg
    10681 ccacgtcgtc atcctcgact cccgccgcat catggagcgt tacgagcccg gggacgaggg
    10741 catccgccac ttcgaggccg aactcgccga ccacctccgc aaacacaccg gatcggaggc
    10801 cgtcgcccag gagaccctcg cgcacgccgc cgaatacctc accttctgcg gccgcacccc
    10861 caacaccgga acggtcgacg caccggtcag cgtgatcacc gaccaggaga aggccgccct
    10921 ctacgcggcc ggacagcacg gcacctggca cggcagctcc accgccacca ccgtcgtcct
    10981 gcgcggctcc ggcctccacg ccgacatgct cgaccccaaa cacctccccc gcaacgccgc
    11041 cctgatccgt accgtgctga cgggagacgc ggcccatggc gactgacacc accctccgca
    11101 aggagaccgt cgacgactgg ggcagccgcg agcgcacccc cggcaccccg ccccgcgtca
    11161 tcgtcatcgg tgcgggcgtg gccggcctct ccaccggctg ctacgcgcag atgagcggcg
    11221 ccaggacccg gatcttcgag aagcacgtgc tgcccggcgg ctgctgcacc gcctggtcga
    11281 gggacggcta cctcttcgac tactgcatcg aatggctcat cggcaccgcg cccggcaacg
    11341 acgcccacca ggtctggcgc gagctgggcg cgctcgacgg caagaccgtc accaacttcg
    11401 aactgttcaa caaggtcgag gacgagcgcg gccgctcggt caccttctac aacgaccccg
    11461 accggctgga ggcccacctg ctggccctct cacccgccga cgcccccctg atccgggcct
    11521 tcacccgcga cctgcggcgg ttcatcgaca tcgagctgta cccgttcctc accgcccccg
    11581 ccctgcggac cgtacgggag cgggcggcga ccctgcgcac ggtgctgccg gccttccggc
    11641 tcttctggcg cacggccgcc accccgatgc acgtcttcgc cgacaagttc caggacccgc
    11701 tgctgcgccg ggccttccgc aacatcttct tccaggaccc ggagggcttc ccgctgctgc
    11761 cgtacctgtt caacatggcg gcggcccacc acctcaacgc cggtttcccg caaggcggtt
    11821 cactcgggct ctcgcgctct gtcgagaacc gctacctggg cctgggcgga gaggtcacct
    11881 accgggcccg cacggagaag atcctcgtcg agaacgaccg cgcgatcggc atcgaactcc
    11941 gcaacggcag aaggtacttc gccgagcaca tcgtctccgc ctgcgacggc cgcaccaccg
    12001 tccacggact gctcgacggc cggtacacca gcccccggat cgacaagctc tacaacgacc
    12061 tcatcgaacg ccccggcacc ctcttccccg cggtcgtctc cgccttcgtc ggcctgcgcg
    12121 gcgacttcga ccccggcgag gcccacagca ccacccacct cctgaccgac gaggacggca
    12181 ggcgcctccc cggcgccctc cagaacagcc tggtcgtcca ggcccgctcc cgctactccg
    12241 acggcttcgc acccccgggc cgctccgtcc tgcactgcac ctacttcagc gactacgcct
    12301 actggaagga gctgcgcacc cgcagccgcc gggagtaccg cggccgcaag cacgaggtgg
    12361 ccgacttcgt ccgcaccttc ctggaacacc gccaccccgg catcaacgac cgcatcgacc
    12421 tcgtcgacat cgcatcgccc gccaccaccc accgctacac cggcaaccac aacggctcga
    12481 tcctcgcctg gaaggccttc tcggacgccg acgacgtcgc cgcccgcctg gtcggcaagg
    12541 accggatgcg gctccccggc ctgagcggct tctccatggc cggacagtgg gtcggcatgg
    12601 gcggcctgat ccgcgccgcc tccaccggcc gcttcgccgt ccagtacctc tgccgcgaac
    12661 tgggcctgga attccgggcc tgggagagcg agggcaccga gccctggcac cccgggatgc
    12721 tgggcgaact gccccagctc gaccgctggt cggcacggga ggacaccggt tcatgaccca
    12781 caggaccacc ggctcccccc gggagcccag ggagtcgatg atcatcatcg ggggcgggct
    12841 cggcggcctc tccaccggct gctacgcccg gatgaacggc taccgcaccc gcatcctgga
    12901 gatgcacgaa ttgcccggcg gttgctgcac cgcctgggag cgcggcggct tcaccctgga
    12961 cgcctgcgtc agctggctcc tcggcagcgg ccccggcaac gagatgcacc agatctggct
    13021 ggagctgggc gccctccagg gaaaggagat ccgccacttc gacgtgttca acatcgtgcg
    13081 cggacaggac gggcgggccg tccacttcta ctccgacccg gaccggctcg aggcccacct
    13141 catcgcgatc tcgcccgccg acgcccgtac cgtacgcaag ttctgcaacc aactgcgcag
    13201 cttccgcaag gcccttgccg tctacccgtt cctcaaaccc gtcggactga tgggccggct
    13261 ggaacggtgg cggatgctcg cctcgttcgt cccgtacttc aacgccgtac gcaccacgat
    13321 cacggtcctg atgaccgagt actccgccaa gttccaggac ccgctgctgc gggaggcgtt
    13381 caacttcatc ctctacgaga agcaccccaa cttccccgtc ctgcccttcc acttccagct
    13441 cgcctcgcac gccaacctct ccgcaggtgt gcccgaaggc ggctcgctcg gcctcgcccg
    13501 gtcgatcgag gcccgctacc gccgcctcgg cggagagatc tcgtacaaca cgaaggtcga
    13561 gacggtgatc gtggaggacg accgcgcggt cggcgtccgg ctcagcgacg gcagcgaact
    13621 gcgcgccgac atcgtggtgt cggcctgcga cggctacacc acgaccatga agttcctcaa
    13681 gggcgcctac ctgggggagg agtaccgcaa gctctacacg gagaccatcc acgaacccgg
    13741 catggtcttc cccggctact tcaccctctt cctcggcctc tcccgcccct tccccgaggg
    13801 cgacccctgc accacctacc tcctcgacga ggccacggcg gcgaagctca ccggcatccg
    13861 ccacgccagc atcaacgtcc agttccgcag ccgccattac cccgaactct ccccggacgg
    13921 caccaccgtc gtctacgcca cctacttctg cgacatcgcc ccctggcggg ccctggacga
    13981 aggccccgag caggtcaccc gcacccgggg cggccaggaa ctgcataccc tgccggtgcg
    14041 ccacggccgc ggctactacg cggccaaacg gcgggcgcgc gagacgctcg tggagttcct
    14101 ggaggagcgc ttccccggca tccgcgacgc catcgtcgta cgggacgtct ccagccccct
    14161 cacccaggtc cgctacaccg gcaactacga cggcacggtc ctgggctggc agcccttcgt
    14221 ggagagcggc gagaagctcg aagagctgat caagaagcac ggtcccgggc tgcccggcct
    14281 cgccaacttc taccagtccg gcgtctgggc caccaccggc ggcctgatcc gggccgccgc
    14341 cgccggacgc cacgtcatgc agttcatctg ccgcgacgac ggaaaaccct tcaccgcgtc
    14401 gctcgaccgg gcggcacccc cgccgaccca ccgcgtcatc cccgtaccga ccggccgctc
    14461 caccgccgcc gcaacgacga cagggaaagg cacatgaaga tcgagaaatg ggtcgtccgc
    14521 gagcacgtcg aaggcgtgcc cgacgtcgac cgcgtctacg agaaggtcgt cgagaacgtc
    14581 gacgtgaccc tggcccccga cgagatgctg ctccgcacgc tgtacgtctc cgtcgacccc
    14641 tacctccagg gcatcgccct cgacaccccc atcggctccc acatgggcgc cgactcgatc
    14701 atggaggtgg tggcggccgg accgcgcgcc gcccacggcg tcggcgacct cgtacagggc
    14761 ttcggcggct ggcgctccca tgtcgtctcc accggcgcgg ccgagctgtg gcagaccggc
    14821 accttcccga tggtcttccc ggcctaccgc aggctcgacc ccggctggta cgacgacgcc
    14881 ctgccgctgg cgaccgcgct gagcgtgatg ggcggccccg gcatgacggc ctggggcacc
    14941 ctcgccaagt acatgacggt gaagcccggc gacaccttcg tcatcagcgg ggcctccggc
    15001 gcggtcggcg ccctcgtcgg ccagctggcc gcgctcgccg gcgcccgggt cgtcggcacc
    15061 acctcctcac cgcagaaggc ggagtacctt ctcggcctcg gcttcgacac ggtcgtggtc
    15121 taccggcaca ccgacggcgc cgacaccgtc cgcgaggcgc tgacccgggc ggccccggac
    15181 ggcgtcgacc gctacttcga caacctcggc ggaaccgtca ccgacgtggt cttctccatg
    15241 ctcaacgtcg gcagccaggt cgcggtctgc tggcagtggg cgacccaggt cggcaacgag
    15301 gagacgggcc cccgcctgct gccctacctg atgttcccgc gcgccacggt ccgggggatc
    15361 ttctcgctgg agtggttcac cgaacagaac tggaaggacc tccacgccga cctcggcagc
    15421 cgggtccgcc ggggcgaggt cgtctgcgac cacaccctcc accacggctt cgacgccatc
    15481 cccgccgcct accggagcct ctacggcgac cgggcggaga gccggggcaa ggtgctggtc
    15541 gccctgtgac caccgcgacc gcacccctca accaccctct tcggcccgga ggttgacgat
    15601 ggccatcacc gacccgtccc tgatccccct gcaccgcctg cggttcgagg agccgggccc
    15661 gccccgcccg ggggagctgc ccacgggcgt ccccgcctgg ctggtgagcc ggtacgccga
    15721 cgtccgccag gtcctctccg acccgcgctt cggccggtcc cggctgtacg cggaggacgc
    15781 acccgccctc tccgacgtac cggacctcgt caacaacccc gacctcatgt tcaaccagga
    15841 cggccccgac catctgcggc tgcgccggac cctgcgccgg gcgttcacgc cgagggccgt
    15901 cgcccgctgg cgcccctgga tcgccgcgat cgtggacgag ctgctggacc ggctggagga
    15961 gcggccccaa ccagcggacg tggtcgagga gttcaccctg cccctccccg tggcggtgat
    16021 cagccgactg atgggtctgg acggttcggc ctgggaccgg atgcggcact ggagcgagca
    16081 cgccttctcg gacgggtcgc acgcggggga ggaggtggag tccgtactga aggagttcag
    16141 cgcgttcggc gcggacctcc tcgcgacccg gcggcacacc cccggcgacg acctggtcag
    16201 cggtctggtc cgggcggccg acgaggaagg cggggttccc gaagcgcagt tggtgagcct
    16261 ggtgtgcggg ctcgtcgtcg gcggccacga cagcacgatg accatgctgg gcaacgggct
    16321 gctctacctc ctgggcgaac gcccggagag ctggccccgc atcggcgcgg acgaggaggc
    16381 ggccggccgg gtcgcggacc ggctgatcca tctcgtcccg ctgggcgacg accgggggac
    16441 ggcccgccac gcggccgcgg acatcgaggt gggcggggtg acgatcccgg cgggcgccat
    16501 cgtcctggcg gactgcggcg ccgccaaccg ggacccggac gtcttccccc gccacacgct
    16561 cgacgacctc ttcgccccgc tggaggcccc caccctctcg ctcggggcgg gggcccacta
    16621 ctgcctgggc gcctggctgg cccgtacgga actccagctc gccctgcacc gcctggccgc
    16681 ccgcttcccg gagctgcggc tggcggagcc ggtggagcgg gtcacctggc ggaccggaac
    16741 gacgtcacgg agcccgcgga ggctgacggt gagctggtag ttcctccgta cgggggtggc
    16801 tgcggagccg ggtcagcgga cctgctcgaa gctcggcccg taggtgcccg ccttgacgcg
    16861 cagcgtctcg aagccgccct cgcccttgtt gccgtacttg ctccagtact ggcaggtcag
    16921 cccggagtcg ccgttgaggt cgacggcctg ggcgacgggg aactcctcgc aggcgagctt
    16981 gctcgcctcg agccccgact ccttgccgta ctgctcgtac agctggtggt agacggtctt
    17041 cgccacgatc agcgacttga gcggcttggc gttgtagaag gtcatgaagc cgccttcctt
    17101 gtacgagtcg ctgatcttga cctcgtacgg aatgacagcg ccctcgtagg tgacgttgca
    17161 ggtgctgacg gccccggcct tctgggtcac cccgtccggg cactcggcgc tggtcttgcc
    17221 cggcaccttg acccgcccga gcacctgctc ctggagct
//
