LOCUS       BGC0002383             31936 bp    DNA     linear   BCT 26-DEC-2020
DEFINITION  Streptomyces sp. SN-593 DNA, nearly complete genome.
ACCESSION   BGC0002383
VERSION     BGC0002383
KEYWORDS    .
SOURCE      Streptomyces sp. SN-593
  ORGANISM  Streptomyces sp. SN-593
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
COMMENT     This work was done in collaboration with Shunji Takahashi, Masashi
            Ueki, Atsushi Toyoda, Yoshiyuki Sakaki and Hiroyuki Osada (RIKEN)
            and Jun Ishikawa (National Institute of Infectious Diseases).
            ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 17:28:56
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 31936
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..31936
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[3693:6200]"
                     /cutoff="20000"
                     /detection_rule="(t2ks and t2clf)"
                     /neighbourhood="35000"
                     /product="T2PKS"
                     /protocluster_number="1"
                     /t2pks_malonyl_elongations="8|9 (Score: 713.4; E-value:
                     1.6e-217)"
                     /t2pks_molecular_weights="acetyl-CoA_8 (Da): 591.579"
                     /t2pks_molecular_weights="acetyl-CoA_9 (Da): 633.615"
                     /t2pks_product_classes="angucycline"
                     /t2pks_starter_units="acetyl-CoA (Score: 0.0; E-value: 0)"
                     /tool="antismash"
     proto_core      3694..6200
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(t2ks and t2clf)"
                     /neighbourhood="35000"
                     /product="T2PKS"
                     /protocluster_number="1"
                     /t2pks_malonyl_elongations="8|9 (Score: 713.4; E-value:
                     1.6e-217)"
                     /t2pks_molecular_weights="acetyl-CoA_8 (Da): 591.579"
                     /t2pks_molecular_weights="acetyl-CoA_9 (Da): 633.615"
                     /t2pks_product_classes="angucycline"
                     /t2pks_starter_units="acetyl-CoA (Score: 0.0; E-value: 0)"
     cand_cluster    1..31936
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(t2ks and t2clf)"
                     /kind="single"
                     /product="T2PKS"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..31936
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0002383"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..31936
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T2PKS"
                     /region_number="1"
                     /rules="(t2ks and t2clf)"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(1..657)
                     /locus_tag="RVR_2900"
     CDS             complement(1..657)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 178.8; E-value: 2e-54)"
                     /gene_kind="regulatory"
                     /locus_tag="RVR_2900"
                     /product="putative two-component system response regulator"
                     /protein_id="BBA97247.1"
                     /transl_table=11
                     /translation="MRLLLVEDDTEAAEVLTRDLRRHGYEVQAVGEGYDAMSASKEADL
                     VVLNLDLRDLDGLEITRRLRDHCDVPIIAVSKRDTEMDRVIGLQAGLDDYLGKPYGFSE
                     LLARIQAVMRRAHARPTAAVVTRGPLQVNLSTREVTLHGRAVELTRKEFDLLALLASKP
                     DAIFSRRQLMSEVWDDDWSEASRTIDTHVSSLRGKLGGYSWIRTVRGVGFRFGHG"
     gene            1669..2637
                     /locus_tag="RVR_2901"
     CDS             1669..2637
                     /codon_start=1
                     /locus_tag="RVR_2901"
                     /product="hypothetical protein"
                     /protein_id="BBA97248.1"
                     /transl_table=11
                     /translation="MTHDSERTARVGCEGVVCRGRSGVPGQARALAPAGSLLCPACVLR
                     LTADLRRMPRLYDECARLLGGSDRPRERTSGGGSPTGLPFNTAAAEARSALVSLLRSWA
                     RLVVEERVVAPPRDTVAGAVAFLVRHVEWLAAHDAAGELTEEVARAVRRARRVTDPSPG
                     RSVRVGTCVVAECGGGLTAVARGGRDGAVVEVRCAAVASHRWSGREWMALGGGAVAAPR
                     EDGGEPAEQPGSVGRPGPAEQPEPTGPPERIADRAQAVQWLSPRDVSLLWGIPSGSVYR
                     RASEQKWRRRSGKGRTFYWKEDVLRSVGADGGDGGDGGEES"
     gene            3371..3697
                     /locus_tag="RVR_2902"
     CDS             3371..3697
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1225:Polyketide synthesis cyclase (Score: 157.5;
                     E-value: 1.5e-48)"
                     /gene_functions="biosynthetic-additional (t2pks) CYC
                     C4-C17/C2-C19 (Score: 199.4; E-value: 1.2e-61)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="RVR_2902"
                     /product="putative cyclase"
                     /protein_id="BBA97249.1"
                     /transl_table=11
                     /translation="MHSTLIVARMETHSAAEVAKLFGAFDTTEMPHRMGTRRRQLFSYR
                     GLYFHLQDFDGEDGGERIEEAKTDPRFVAISDDLKPLITAYDPATWRSPADAMAHRFYH
                     WAAR"
     gene            3694..4974
                     /locus_tag="RVR_2903"
     CDS             3694..4974
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (8-418). E-value:
                     1.4e-60. Score: 197.2. Matches aSDomain:
                     nrpspksdomains_RVR_2903_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2ks"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 511; E-value:
                     4.2e-155)"
                     /gene_functions="biosynthetic-additional (t2pks) KS (Score:
                     791.8; E-value: 3.1e-241)"
                     /gene_kind="biosynthetic"
                     /locus_tag="RVR_2903"
                     /product="putative beta-ketoacyl synthase"
                     /protein_id="BBA97250.1"
                     /sec_met_domain="t2ks (E-value: 3.3e-250, bitscore: 820.9,
                     seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAPHGRRVVITGIGVTAPRGVGVKDFWSLLTDGRSATRRISFFD
                     PSPFRSQVAAEVDFDAELLGLSSQEIRRMDRAAQFAVVTAREAMADSGLDFGTLDPHRT
                     GVTIGSAVGATTGLDEEYRTVSDSGRLDLVDHTYAVPHLYNYLVPSSFAVEVAWAVGAE
                     GPATVVSTGCTSGLDAVGYATELIREGSADVMVAGAADAPISPITVACFDAIKATTPRN
                     DDPEHASRPFDRTRDGFVLGEGSAVFVLEELDSARRRGAHIYAEVAGYATRSNAFHMTG
                     LRPDGREMAEAIRVALDEARLDPHDVDYVNAHGSGTYQNDRHETAALKRGLGTHAHRVP
                     VSSIKSMVGHSLGAIGSIEIAASALAMEHHVVPPTANLHTPDPECDLDYVPLTARDWRT
                     DAVLTVGSGFGGFQSAMVLARPGRSET"
     aSDomain        3718..4947
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_RVR_2903_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="1.40E-60"
                     /label="RVR_2903_PKS_KS.1"
                     /locus_tag="RVR_2903"
                     /protein_end="418"
                     /protein_start="8"
                     /score="197.2"
                     /tool="antismash"
                     /translation="VVITGIGVTAPRGVGVKDFWSLLTDGRSATRRISFFDPSPFRSQV
                     AAEVDFDAELLGLSSQEIRRMDRAAQFAVVTAREAMADSGLDFGTLDPHRTGVTIGSAV
                     GATTGLDEEYRTVSDSGRLDLVDHTYAVPHLYNYLVPSSFAVEVAWAVGAEGPATVVST
                     GCTSGLDAVGYATELIREGSADVMVAGAADAPISPITVACFDAIKATTPRNDDPEHASR
                     PFDRTRDGFVLGEGSAVFVLEELDSARRRGAHIYAEVAGYATRSNAFHMTGLRPDGREM
                     AEAIRVALDEARLDPHDVDYVNAHGSGTYQNDRHETAALKRGLGTHAHRVPVSSIKSMV
                     GHSLGAIGSIEIAASALAMEHHVVPPTANLHTPDPECDLDYVPLTARDWRTDAVLTVGS
                     GFGGFQSAMVL"
     gene            4971..6200
                     /locus_tag="RVR_2904"
     CDS             4971..6200
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (71-404). E-value:
                     4.5e-27. Score: 86.8. Matches aSDomain:
                     nrpspksdomains_RVR_2904_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2clf"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093:Beta-ketoacyl synthase (Score: 677.3; E-value:
                     1e-205)"
                     /gene_functions="biosynthetic-additional (t2pks) CLF 8|9
                     (Score: 713.4; E-value: 1.6e-217)"
                     /gene_kind="biosynthetic"
                     /locus_tag="RVR_2904"
                     /product="putative chain length determinant"
                     /protein_id="BBA97251.1"
                     /sec_met_domain="t2clf (E-value: 9.9e-215, bitscore: 703.5,
                     seeds: 26, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGAGVRTVVTGLGVAAPNGCGVEAYWAAVRKGTSGIGRVSRFDP
                     AQYPARLAGEITDFVAEDHLPGRLLPQTDRMTRIALASADWALADAGVDPRNLPEYGMG
                     VITASSSGGFEFGQRELRALWSKGGRHVSAYQSFAWFYAVNSGQISIRNGMRGPSGVVV
                     SDQAGGLDALAQARRQIRKGTGLVMSGAVDASICPWGWVAQMASGRLSTSEDPERAYLP
                     FDAAARGHVPGEGGALLVLEDLEHARARQARTPYGEIAGYGSAMDPRPGSGRPPTLVRA
                     IELALADAGAAPEDIDVVFADAAAVPALDRIEAEAVSRVFGPRGVPVTAPKTMTGRLYS
                     GAAPLDVAAALLALRDQVIPPSVGVTPDPGYALDLVVGAERAAPVRSALVVARGHGGFN
                     SALVVRAVRT"
     aSDomain        5184..6182
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_RVR_2904_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="4.50E-27"
                     /label="RVR_2904_PKS_KS.1"
                     /locus_tag="RVR_2904"
                     /protein_end="404"
                     /protein_start="71"
                     /score="86.8"
                     /tool="antismash"
                     /translation="QTDRMTRIALASADWALADAGVDPRNLPEYGMGVITASSSGGFEF
                     GQRELRALWSKGGRHVSAYQSFAWFYAVNSGQISIRNGMRGPSGVVVSDQAGGLDALAQ
                     ARRQIRKGTGLVMSGAVDASICPWGWVAQMASGRLSTSEDPERAYLPFDAAARGHVPGE
                     GGALLVLEDLEHARARQARTPYGEIAGYGSAMDPRPGSGRPPTLVRAIELALADAGAAP
                     EDIDVVFADAAAVPALDRIEAEAVSRVFGPRGVPVTAPKTMTGRLYSGAAPLDVAAALL
                     ALRDQVIPPSVGVTPDPGYALDLVVGAERAAPVRSALVVARGHGGFNSALVV"
     gene            6407..6676
                     /locus_tag="RVR_2905"
     CDS             6407..6676
                     /NRPS_PKS="Domain: ACP (12-80). E-value: 5.9e-20. Score:
                     63.3. Matches aSDomain: nrpspksdomains_RVR_2905_ACP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1129:acyl carrier protein (Score: 122.1; E-value:
                     1.3e-37)"
                     /gene_functions="biosynthetic-additional (t2pks) ACP
                     (Score: 139.4; E-value: 6.7e-44)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="RVR_2905"
                     /product="putative acyl carrier protein"
                     /protein_id="BBA97252.1"
                     /sec_met_domain="PP-binding (E-value: 2.7e-14, bitscore:
                     44.4, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAHEFTVADLKRILREGAGADEGVDLDGDILDTDFESLGYDSLA
                     MLETGSRIEREFGVTLDDEVLTEAETPRALIEAVNHVVVRSGAV"
     aSDomain        6443..6646
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_RVR_2905_ACP.1"
                     /evalue="5.90E-20"
                     /label="RVR_2905_ACP.1"
                     /locus_tag="RVR_2905"
                     /protein_end="80"
                     /protein_start="12"
                     /score="63.3"
                     /tool="antismash"
                     /translation="RILREGAGADEGVDLDGDILDTDFESLGYDSLAMLETGSRIEREF
                     GVTLDDEVLTEAETPRALIEAVN"
     gene            6938..7723
                     /locus_tag="RVR_2907"
     CDS             6938..7723
                     /NRPS_PKS="Domain: PKS_KR (7-160). E-value: 4.8e-13. Score:
                     41.3. Matches aSDomain: nrpspksdomains_RVR_2907_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     271; E-value: 1.5e-82)"
                     /gene_functions="biosynthetic-additional (t2pks) KR C9
                     (Score: 493.3; E-value: 3.4e-151)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="RVR_2907"
                     /product="putative ketoreductase"
                     /protein_id="BBA97253.1"
                     /sec_met_domain="adh_short (E-value: 1.5e-40, bitscore:
                     129.9, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEQHPKVAVVTGATSGIGLATARLLARRDHRVFLCARTQESVTR
                     TVKELVDEGLDVDGAPCDVRSAADVRRFVRQAVDRFGPIDVLVNNAGRSGGGVTADITD
                     ELWSDVIDTNLNSVFRMTREVLTAGGMRRRGSARIVNIASTAGKQGVVLGAPYSASKHG
                     VVGFTKALGNELAPTGITVNAVCPGYVETPMAQRVRQGYAAAYDTSEDAILERFQAKIP
                     LGRYSTPEEVAGLVGYLVSDTAASITAQALNVCGGLGNF"
     aSDomain        6959..7417
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_RVR_2907_PKS_KR.1"
                     /evalue="4.80E-13"
                     /label="RVR_2907_PKS_KR.1"
                     /locus_tag="RVR_2907"
                     /protein_end="160"
                     /protein_start="7"
                     /score="41.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VAVVTGATSGIGLATARLLARRDHRVFLCARTQESVTRTVKELVD
                     EGLDVDGAPCDVRSAADVRRFVRQAVDRFGPIDVLVNNAGRSGGGVTADITDELWSDVI
                     DTNLNSVFRMTREVLTAGGMRRRGSARIVNIASTAGKQGVVLGAPYSAS"
     CDS_motif       6965..7048
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_RVR_2907_0001"
                     /evalue="1.30E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="RVR_2907"
                     /protein_end="37"
                     /protein_start="9"
                     /score="21.0"
                     /tool="antismash"
                     /translation="VVTGATSGIGLATARLLARRDHRVFLCA"
     CDS_motif       7334..7465
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_RVR_2907_0002"
                     /evalue="1.20E+01"
                     /label="PKSI-KR_m1"
                     /locus_tag="RVR_2907"
                     /protein_end="176"
                     /protein_start="132"
                     /score="-1.2"
                     /tool="antismash"
                     /translation="RRGSARIVNIASTAGKQGVVLGAPYSASKHGVVGFTKALGNELA"
     gene            7746..8681
                     /locus_tag="RVR_2908"
     CDS             7746..8681
                     /NRPS_PKS="Domain: Polyketide_cyc2 (4-146). E-value:
                     3.2e-17. Score: 55.1. Matches aSDomain:
                     nrpspksdomains_RVR_2908_Polyketide_cyc2.1"
                     /NRPS_PKS="Domain: Polyketide_cyc2 (155-307). E-value:
                     1.4e-08. Score: 27.1. Matches aSDomain:
                     nrpspksdomains_RVR_2908_Polyketide_cyc2.2"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1128:cyclase/dehydrase (Score: 466.6; E-value:
                     6.4e-142)"
                     /gene_functions="biosynthetic-additional (t2pks) CYC C7-C12
                     (Score: 502.1; E-value: 1.1e-153)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="RVR_2908"
                     /product="putative aromatase"
                     /protein_id="BBA97254.1"
                     /transl_table=11
                     /translation="MTNRQVEHEITVAAPAAAVYRLLAEVENWPRIFPPTIHVEHLERG
                     ADDERIRIWATANGGVKSWTSHRALDPRTLRIAFRQEVSSPPVAAMGGTWIVEPLSDAA
                     SRVRLLHDYRAVDDDPEGLAWIDEAVDRNSRSELAALKQNVERAHAAEEITFSFEDTVR
                     VRGRAADVYDFVNEAGQWARRLPHVASVRLEEETPGLQVLEMDTLAQDGSTHTTKSYRV
                     TFPHRGIAYKQVTLPALMALHTGYWTFAEDEQGVAATSRHTVVLDTGNIARVLGPQASV
                     ADARGYVRRALSTNSRITLAHAKDYAEGRR"
     aSDomain        7758..8183
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_RVR_2908_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="3.20E-17"
                     /label="RVR_2908_Polyketide_cyc2.1"
                     /locus_tag="RVR_2908"
                     /protein_end="146"
                     /protein_start="4"
                     /score="55.1"
                     /tool="antismash"
                     /translation="QVEHEITVAAPAAAVYRLLAEVENWPRIFPPTIHVEHLERGADDE
                     RIRIWATANGGVKSWTSHRALDPRTLRIAFRQEVSSPPVAAMGGTWIVEPLSDAASRVR
                     LLHDYRAVDDDPEGLAWIDEAVDRNSRSELAALKQNVE"
     aSModule        7758..8666
                     /domains="nrpspksdomains_RVR_2908_Polyketide_cyc2.1"
                     /domains="nrpspksdomains_RVR_2908_Polyketide_cyc2.2"
                     /incomplete
                     /locus_tags="RVR_2908"
                     /tool="antismash"
                     /type="unknown"
     aSDomain        8211..8666
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_RVR_2908_Polyketide_cyc2.2"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="1.40E-08"
                     /label="RVR_2908_Polyketide_cyc2.2"
                     /locus_tag="RVR_2908"
                     /protein_end="307"
                     /protein_start="155"
                     /score="27.1"
                     /tool="antismash"
                     /translation="FSFEDTVRVRGRAADVYDFVNEAGQWARRLPHVASVRLEEETPGL
                     QVLEMDTLAQDGSTHTTKSYRVTFPHRGIAYKQVTLPALMALHTGYWTFAEDEQGVAAT
                     SRHTVVLDTGNIARVLGPQASVADARGYVRRALSTNSRITLAHAKDYA"
     gene            8678..10183
                     /locus_tag="RVR_2909"
     CDS             8678..10183
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050:monooxygenase FAD-binding (Score: 551.5; E-value:
                     3.4e-167)"
                     /gene_functions="biosynthetic-additional (t2pks) OXY
                     (Score: 599.6; E-value: 1e-182)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="RVR_2909"
                     /product="putative oxygenase"
                     /protein_id="BBA97255.1"
                     /transl_table=11
                     /translation="MTGHARAADTDVVVVGAGPVGLMLAGELRAGGARVTVLERLAAPT
                     GESRASTLHARTMEILDERGLLDAWGTVPRAAGGHFGGIALDFGGLDSRYAGQWKVPQT
                     RTEHLLGERAVRLGAVVRRGHALVGLRQTGSGVEAETEGPAGRSRIRAAYLVGCDGEDS
                     TVRRLAGFAFPGTDATRELLRADIAGIDVPDRRFERHEHGLAIAHRRPDGITRVMVHQF
                     GRAAAPRAAAPGIAEVTSVWAKVTGEDIGAGTPVWVDAFGNARRQAERYRAGRVLLAGD
                     AAHAQMPVGGQALNLGLQDAVNLGWKLAAQVRGRAPQGLLDSYHDERHAVGSRVLTNIE
                     AQATLLLGGPEVEPLRAVVTDLLGHDEVVGHLAGMISGLDVRYPVGDDGPRGGHPLLGG
                     RVPHWELATASGASSTTELLRAGRGVLLDLAGCLPPGAGAGWADRVRTVTAAPAPADGA
                     PSRPGTAAVPAVLIRPDGHVVWCADGTAGPEAALRRWFGDPHA"
     gene            10335..11879
                     /locus_tag="RVR_2912"
     CDS             10335..11879
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050:monooxygenase FAD-binding (Score: 567.1; E-value:
                     6.4e-172)"
                     /gene_functions="biosynthetic-additional (t2pks) OXY
                     (Score: 593.7; E-value: 6.3e-181)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="RVR_2912"
                     /product="putative oxygenase"
                     /protein_id="BBA97256.1"
                     /transl_table=11
                     /translation="MDAPFDAEVVVVGAGPTGLMLAGELLLAGVRVTVLDRLAEPTTES
                     RGLGFTPRTMEVFAQRGLVDRFDGLDIPLQTTTRGHFGGLPLDFGVFPEAHPAVANLPQ
                     FHTESMLRGWVAELGCDLRRGHTVTGLADTGEAVEVTVERPGGPRVLRARYVVGCDGGR
                     STVRGLAGFAFPGTPATLELFLADVRGCGLRPRFIGEWLPGGVAMAAPIGDGIDRVVVC
                     ERDAPPRRRTRPVAYAEVAAGWRRLTGEDISHGEPLWVSAFGDATRLATEYRRGRVLLA
                     GDAAHVHLPAGGLGMNTGIQDAFNLGWKLAAVVRGHAPDALLDTYHDERHAVGERLLDT
                     TRAQGLLFLGGSVMQPLRDVLGELTGHEAVHRRLAGTVSGLGIRYPMGPGGGDARQGRP
                     GGDPPAGGHPLLGLRMPDLEIAGGTGTTSVFALLRAARGLLLDLAHDASLRRAARPWAD
                     RVDVVAAEPAADSPLPRVDAVLVRPDGHVAWAAPGGREDLADAMTRWFGAPRAAAA"
     gene            11897..12478
                     /locus_tag="RVR_2914"
     CDS             11897..12478
                     /codon_start=1
                     /locus_tag="RVR_2914"
                     /product="hypothetical protein"
                     /protein_id="BBA97257.1"
                     /transl_table=11
                     /translation="MARTAQEADALRRLADRMDVRELVDRYLAGLDEGRFDDTWARSVF
                     TEDGRFEVPTGGHDGVAGMAEATAAMIGRWRSTHHLAAGHLVEIDGDRARVRGSLVVTH
                     LYPPGAVVREPAPRESGPRKPGPRESGLQDAPGRVGAPDAPGAPEPFQVGDRFEGAAVR
                     TGAGWRFARLAFEVVWTRGTPPGRVEFPHP"
     gene            12534..13805
                     /locus_tag="RVR_2916"
     CDS             12534..13805
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MGT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1062:glycosyltransferase, MGT family (Score: 340.7;
                     E-value: 2.4e-103)"
                     /gene_functions="biosynthetic-additional (t2pks) GT (Score:
                     400.1; E-value: 3.2e-122)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="RVR_2916"
                     /product="putative glycosyl transferase"
                     /protein_id="BBA97258.1"
                     /sec_met_domain="MGT (E-value: 1.2e-123, bitscore: 403.9,
                     seeds: 193, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRILIAVAPLTAHLYPSVPLAWALQTAGHDVRVASNSGLVEQITA
                     AGLTAVGLGERTLPPAPVTDEELDRFSDALAFEAGSDADQLWRAIRFYLVAAHARYHPD
                     REGRQEPADNLVEAARSWRPDLVVWDPACPAASVAARVCGAASARMMWGPDYLGWIRGR
                     LLERMADPASGVRPDTDPLAANLAPVFERYGHGFSEDLLFGDFTVDPIPSRLPRHPGVR
                     RVPMRWVPYTGAAPVPPWLSRPPSRPRVCLSLGVTGRTVQEGRDARVAAALEAAAGMDV
                     EVVATVNASQLGPDTRVPDNVRLHDYVPLTQVMPTCSAIVHHGGFGTFFAAAAHRVPQM
                     IVTDELGSSLSSSRYLTSKGAGVALPGDGLTADRLGEELSRVLTEPSFREGADAVFADL
                     ASAPRPTEIVPVLERMAARHRKGA"
     gene            13810..14385
                     /locus_tag="RVR_2917"
     CDS             13810..14385
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) dTDP_sugar_isom"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="RVR_2917"
                     /product="putative epimerase"
                     /protein_id="BBA97259.1"
                     /sec_met_domain="dTDP_sugar_isom (E-value: 1.8e-51,
                     bitscore: 165.0, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDVVETTVPGAFVFTPRQIRDERGAFFEAFRDDQVEAATGRPFRP
                     EQINYSVSRRNTLRGIHGVAVPPGQAKYVTCVRGALRDIVVDLRVGSPTFGAHHVTSLD
                     AGSARCVYVPDGVGHGFLSLTDDACICYVVSTRHVPGTQIDINPLDPDLALPWEFDEPP
                     LMSEKDATAPGVHAALAAGSLANWHDVR"
     gene            14540..16804
                     /locus_tag="RVR_2919"
     CDS             14540..16804
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1138:FAD linked oxidase domain protein (Score: 89.3;
                     E-value: 6.6e-27)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="RVR_2919"
                     /product="putative hydrolase"
                     /protein_id="BBA97260.1"
                     /transl_table=11
                     /translation="MPDTHFAADPAQTPVGVWTGSVRHDDQTDPYTISFAPDGTIALRT
                     PVTVGTGTWVAGPPGRFSYELTEVFTPASGHAGHLEAHVEGRLDGSAHSGTGTARIYTP
                     DGVLVHTTTAESAGERVGDRPAAWHALVGLGAPIRGRTLHRGDDGFDEAVSRRPGNGGR
                     PEAVVVAADADDVAAAVRFAAEARRAVAVEPGGPAPADGAVLVVTADLTELAVDQRAAT
                     ARIGAGLRWGEVLAAAAEHGLAPLRDLPADAGAADYLTGDASWARGAAAPASHDVRSLE
                     LVTADGLVRTTSPTREPDLFWAVRGGASGLGVLTGAEIGLAPALPADGGEPAGARPAAP
                     HPHPHPNARRLAELKAAYDPHDLFRTHHSTPPSPTAGERGTTGMPLSTDPQSAMAELVK
                     LAGAQAARADAERKVSPEVIRAVVDAGFARWRVPARWGGAERSHAELTAAVARLGEECS
                     STAWLASVAAYSARYVACMPEQGQADIWADGPDVLAAIVFKPLGTVVPVDGGFRLSGSW
                     TYVSGVDHFDWALLTGPGPGPSAAGQPMRLFAVPRRDYAYEDTWSSLGMRATGSHTLVL
                     DDVFVPEHRTCLREDAMRGALVGLPGYTQLSNPAVSGLMFVSPVLGAARAALAVAAQSV
                     AVAPTGPRTHAGQPYQVDFARAAGEIDAAQLLLERAAAVADGDAVPPELARRNRRDCAL
                     ALQMLIGAVDRLLRIGGTRAQDDGHPLQRYWRDVRSVSSHAVMQFEPAGLAFTEGLVGQ
                     P"
     gene            16816..17646
                     /locus_tag="RVR_2921"
     CDS             16816..17646
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199:NmrA family
                     protein (Score: 243; E-value: 7.5e-74)"
                     /gene_kind="other"
                     /locus_tag="RVR_2921"
                     /product="hypothetical protein"
                     /protein_id="BBA97261.1"
                     /transl_table=11
                     /translation="MILVTGATGHVGRPLVEELSAAGRKVRALSRDPARAGLPAGVEVA
                     ATSDLPLDGVTSVFLVTAAFPDGCAEPIARMKAAGVRRIVALSSYSVLDDDPRNMIGVR
                     HRELERRIEETGAEWTFLRPAGGFAATALEWAARIRADGVARSPFADARTAPVHERDIA
                     AVAARALLTDDLVGEAPLFSGPESLSYADRARIIGEVAGRPVRFEELTPDQARQEWLRA
                     GVPPHAVEARLRMFARLVGHPHEISPVDPYLGRPGLSFARWAADHIDSFREAAS"
     gene            17643..18467
                     /locus_tag="RVR_2922"
     CDS             17643..18467
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199:NmrA family
                     protein (Score: 265.5; E-value: 1.1e-80)"
                     /gene_kind="other"
                     /locus_tag="RVR_2922"
                     /product="hypothetical protein"
                     /protein_id="BBA97262.1"
                     /transl_table=11
                     /translation="MILVTGARGNVGGELLRQLSAGGHAVRALTRDAARAGLPAGADVA
                     EGDFGTAGSLAAALAGADSLFLMTSGHETAVLREAVRAGVRRVVLLSSMAATTRPQSLI
                     GRMHREAELAVEASGVEWTFLRPGQFASNTLAWRSQLAAGDVVRTPFADVALPAVHPGD
                     IAAVARTALTRNGHAGQAYPLSGPEPVTPVEQVAAVGEAIGRKLRHEEIGPEQAAAAMA
                     AHMPAPIVAASLEFLGSPTPEETRPVPTVEKVTGTPARTFAQWARDNADGFR"
     gene            18545..19033
                     /locus_tag="RVR_2924"
     CDS             18545..19033
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1160:flavin reductase domain protein FMN-binding
                     (Score: 120.1; E-value: 1.2e-36)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="RVR_2924"
                     /product="putative flavin-dependent reductase"
                     /protein_id="BBA97263.1"
                     /transl_table=11
                     /translation="MLTQRGFRDVLGCFSTGVVLVTADHDGAPVGMAVNSFTSVSLDPP
                     LIAFCVALTSTTWPLIRATGGFAITILSDTQEDVCRVFSAHGADRFADGDWTRTPAGRA
                     VTADGLGWLDCRIRTVQVEGDHELVIAQALDWSIGADARPLIFHSGRYASLRERSDAE"
     gene            19151..20677
                     /locus_tag="RVR_2925"
     CDS             19151..20677
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050:monooxygenase FAD-binding (Score: 495.9; E-value:
                     2.4e-150)"
                     /gene_functions="biosynthetic-additional (t2pks) OXY
                     (Score: 479.4; E-value: 3.1e-146)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="RVR_2925"
                     /product="putative monooxygenase"
                     /protein_id="BBA97264.1"
                     /transl_table=11
                     /translation="MTGVIVAGAGPTGLMLACELRLAGVDVLVVERLAEPNGRSRAGGL
                     HARSVELFDQRGIAERFVAAGRPGPFAHFSFIPLDIRDLPTRFPYALAIPQAQVERLLE
                     ERAVELGVRVRRSAEVVDLRQDATGVDVRIAGERGVEWLRAGYLVGCDGGRGAVRKLAG
                     IGLSGTPATLTALLGDVVLTDPPADVVFGADSRREHGSVMIFPADVPGLHRVITMEFGK
                     VTERDSPVTLDTLRQACLGLGGTDFGMHDPHWLSSFSDAARQADRYREGRVLLAGDAAH
                     VHFPSSGQGMNLGLQDAVNLGWKLAAVARGQAPDELLDSYGAERRPAVERMLDSTRAQT
                     ALWRPDAQIEALRGVFGALVGSEEVNRALGGTCTQLDVRYPLGDGSPALGRRMPDLDIT
                     SPSGHTRVFESLHAGRPVLLDLGGRPGLRAALEGWTDRVDLVEARCEDDFWSYPVIGDV
                     PAATAVLIRPDGHVAWVAPAAPAADAVASDASAASLGSALTRWFGPARGH"
     gene            20803..21861
                     /locus_tag="RVR_2927"
     CDS             20803..21861
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:O-methyltransferase (Score: 269.1; E-value:
                     9.5e-82)"
                     /gene_functions="biosynthetic-additional (t2pks) MET
                     (Score: 282.0; E-value: 1.5e-86)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="RVR_2927"
                     /product="putative O-methyltransferase"
                     /protein_id="BBA97265.1"
                     /transl_table=11
                     /translation="MSKDELTPSQEAPALPPEFATLMRLGDLVTPMALRVAARLRLVDH
                     LRGGVHDVESLAKATGSHQQALGRLIRHLVAVEVLEESEPGHYTPTALGELLAHDHPVT
                     QVGWLDPTHMIGRADLALIHLFEAVRDGRPVYERQYGKEFWEDVSADPVLSATFYDLMA
                     HGQKHIFGLAVAQHDWSGARHLLDVGGGDGDLIATLLAAEPGIRGTLVELPGPAARART
                     KFEEAGLAGRAEVVAGSFFDPLPVTADVIALSFVLHNWSDQDAVRILRNCAQALEPGGS
                     LLLIECAEQSPSAPDPAFTSGDLRMMVYFEGRERTHDQWRELATAAGMRIDSVSGALAY
                     GARVLTLVKASS"
     gene            22011..23057
                     /locus_tag="RVR_2929"
     CDS             22011..23057
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:O-methyltransferase (Score: 330.4; E-value:
                     2.1e-100)"
                     /gene_functions="biosynthetic-additional (t2pks) MET
                     (Score: 273.3; E-value: 6.3e-84)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="RVR_2929"
                     /product="putative O-methyltransferase"
                     /protein_id="BBA97266.1"
                     /transl_table=11
                     /translation="MAHDEVRAAAADDRGHVIRLVFGNLAARALHAAVELRIVELIGDG
                     QRSAADLAARAGTDPQSTLRLLRALTALGLLREPVPGTFSATPAGALLDPGAPGSMAAL
                     VLSSATMEQMMRPGWDYLADSVRTGDTSFEKVFDKDFFSHLRDHPERSARFNEAMSQAT
                     RSTAAVLPGSFDFGRFGTVADVGGGDGTLLAAVLREHTSLTGILHDTEEGLAQAPETLR
                     RDGLADRCSLVPGDFFTSVPEGADVYLVKSILHDWPDDRCATILGHCREVLPAGGRVLI
                     VEPVLAEAVDPGAVGLYLGDLNMLVNWGGRERTRTEFDAVCHRAGLEIVSVTPLAGPGF
                     SLIEARAV"
     gene            23304..24692
                     /locus_tag="RVR_2930"
     CDS             23304..24692
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1138:FAD linked oxidase domain protein (Score: 361.7;
                     E-value: 1.5e-109)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="RVR_2930"
                     /product="putative FAD-dependent oxygenase"
                     /protein_id="BBA97267.1"
                     /transl_table=11
                     /translation="MTAPLDRAPLSVGELDPARYGQVIGPGDAGYDAARTVYAGDVDRR
                     PAVVLRPGDAEQVAHVVALARETGLELAVRGGGHSAAGHSVCEGGIVLDLAGMRGLEID
                     AEARTAWAEAGVLAGEYTEAAARHGLATGFGDSAAVGVAGITLGGGIGYLTRKHGMTAD
                     DLLAAEIVTADGALLSVDERHHPDLFWAIRGGGGNFGVATRLKLRLHELDGVYGGMMVT
                     PVTPEILEAFVAEAEAAPDELSTIVNVWTAPRFPFIPKEYHGRPVILAMLCYAGPAEEG
                     EKVVDRFRAIVPPLADLVKAMPYPGMFPPVNPDEHPISAARNMFIDRVDRATAETIVER
                     ISTSTARMASAQLRVLGGALARVPSEATAFAHRRSRIMAHLAAVHTGEPDVHEAWVEEF
                     AAAIRQSDSGSYANFVAAADAEQVQNAMYPGATWERLTRVKAEYDPSNLFRSNHNIPPA
                     TARG"
     misc_feature    23652..23654
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            25012..26079
                     /locus_tag="RVR_2931"
     CDS             25012..26079
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 315.2; E-value:
                     6.8e-96)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="RVR_2931"
                     /product="putative dNDP-glucose synthetase"
                     /protein_id="BBA97268.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 1.6e-15, bitscore:
                     48.6, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKALVLAGGSGTRLRPFSYSMPKQLIPIANTPVLVHVLRGVRDLG
                     VTEAGVVVGDRGPEIEAVLGDGSRFGLRITYIPQDAPRGLAHAVSVARGFLGDDDFVMY
                     LGDNMLPDGITGIAEQFAAHRPAAQVVVHKVPDPRSFGVAELGPDGEVLALAEKPAHPR
                     SDMALIGVYFFTPAIHEAVRAIGPSARGELEITDAIQWLVSSGADVRAGQYDGYWKDTG
                     EVEGVLECNSRLLDRLGRRVGGHVDDASVLVGRVVVEAGARVLRSLVQGPAIIGAGTVV
                     EDSHVGPYTSIGRNCVVAGSRLESSMALDGAKVTGVLGLRDSLIGRAALVGTTGAGADH
                     HCLVVGDHTRVEVAA"
     gene            26076..27113
                     /locus_tag="RVR_2932"
     CDS             26076..27113
                     /NRPS_PKS="Domain: NAD_binding_4 (4-181). E-value: 3.3e-20.
                     Score: 64.1. Matches aSDomain:
                     nrpspksdomains_RVR_2932_NAD_binding_4.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score: 346;
                     E-value: 3.4e-105)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="RVR_2932"
                     /product="putative dTDP-glucose 4,6-dehydratase"
                     /protein_id="BBA97269.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 3.5e-21, bitscore:
                     66.3, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 4.1e-21,
                     bitscore: 66.1, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 1.6e-20, bitscore:
                     64.1, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRILVTGAAGFIGSHFVRELLADAYAGWAGAHVTALDKLTYAGNR
                     DNLPAAHERLAFVHGDVCDRDLLAELLPGHDAVVHFAAESHVDRSLEHAGAFFRTNVLG
                     TQTLLDAVLDSDVERVVHVSTDEVYGSIEEGSWTEECPLAPNSPYAASKAGADLVARAY
                     WRTHGVDLSVTRCSNNYGPFQHPEKLIPRFVTNLLEGRRVPLYGDGRNVREWLHVDDHC
                     RGVHLVLNHGQPGEVYHIGGGNAYTNLALTEALLDLTGAGEEMVRRVPDRRGHDLRYSI
                     DDSKIREQLGYAPRTDFATGLAETVAWYRDNPDWWKAAAHGESPAPGENPADGARHEDG
                     ARHAV"
     aSDomain        26088..26618
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_RVR_2932_NAD_binding_4.1"
                     /evalue="3.30E-20"
                     /label="RVR_2932_NAD_binding_4.1"
                     /locus_tag="RVR_2932"
                     /protein_end="181"
                     /protein_start="4"
                     /score="64.1"
                     /tool="antismash"
                     /translation="VTGAAGFIGSHFVRELLADAYAGWAGAHVTALDKLTYAGNRDNLP
                     AAHERLAFVHGDVCDRDLLAELLPGHDAVVHFAAESHVDRSLEHAGAFFRTNVLGTQTL
                     LDAVLDSDVERVVHVSTDEVYGSIEEGSWTEECPLAPNSPYAASKAGADLVARAYWRTH
                     GVDLSVTRCSNNYG"
     gene            27139..28140
                     /locus_tag="RVR_2934"
     CDS             27139..28140
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score:
                     148.8; E-value: 3.9e-45)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="RVR_2934"
                     /product="putative NDP-hexose 4-ketoreductase"
                     /protein_id="BBA97270.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 2e-14, bitscore:
                     44.1, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVVLGGTGFVGRHVVEGFAALGASVLPVSRTGGHAGARVRPPLRL
                     DLLAATPGRIAGMLGEAGADVVVNAAGQVWRSDEEQMAAGNAALVERLLTALASMPGDP
                     PRLVQLGTVHEYGAGAPDAGTGEDHPPAPVTAYGRTKLLGTRAVLGAVQERGVDAVVLR
                     LANVIGSGVPEGSLFGRVAAHLGAAAHAVRRGGRAAELRLPPLRAARDLVDARDAAAAV
                     LAAATAPGAAVTGRVVNVGRGEAVPMRGLIDRMVALSGIRVPVVEEPLSPSSRTDVAWQ
                     RLEIARAGRLLGWRPRRDLDDSLRDLLAPVLPPDRPPLGGTVHAPHPEEESP"
     gene            28137..29441
                     /locus_tag="RVR_2935"
     CDS             28137..29441
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056:DegT/DnrJ/EryC1/StrS aminotransferase (Score:
                     380.2; E-value: 1.9e-115)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="RVR_2935"
                     /product="putative NDP-hexose 3-dehydratase"
                     /protein_id="BBA97271.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 1.6e-102,
                     bitscore: 334.2, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDRKERILEDVRRHHQEVSPEREFVPGTTEIWPSGAVLDETDRA
                     ALVEAALDMRIAAGRSARSFESSFARRMGRRKAHLTNSGSSANLLAVSALTSHVLGDRR
                     LRPGDEVITVAAGFPTTVNPILQNGLVPVFVDVDLATCNTTADRVAAAIGPRTRAIIVA
                     HALGNPFPVTEIARLAEEHGLFLIEDNCDAVGSRYDGKLTGSFGAMATVSFYPAHHLTM
                     GEGGCVLTSDLGLARIVESLRDWGRDCWCEPGENDKCLKRFSYQMGTLPAGYDHKYIFS
                     HVGYNLKATDIQAALGLSQLARLDDFIAARKRNWRRLRDSLDGVPGLLLPEATPRSDPS
                     WFGFVLTVDPRAAYSRAELVAFLEARKIGTRRLFAGNLTRHPAYIGRPFRVVGGLENSD
                     VIADHTFWIGVYPALTDEMLDYVSASIKEFAASHG"
     gene            29571..30980
                     /locus_tag="RVR_2936"
     CDS             29571..30980
                     /codon_start=1
                     /locus_tag="RVR_2936"
                     /product="putative NDP-hexose 2,3-dehydratase"
                     /protein_id="BBA97272.1"
                     /transl_table=11
                     /translation="MLSPPLRPPLQARVDARLRSRIALSAAAEEGVQLRTGDFAAWLAE
                     RGRATDFRVERIPFAELDGWSFDERTGNLGHRSGRFFTVEGLHVTEEAGPFGDGPYADW
                     YQPIIKQPEVGILGILVKEFDGVPHFLMQAKMEPGNPNLLQLSPTVQATRSNYTKAHKG
                     ADVKYIEYFAGPRRGRVIADVLQSEHGSWFYRKSNRNMIVEATGDVPLLDDFCWLTLGQ
                     ISALLHRDNVVNMDSRTVLSCLPHPDTAARALLSDIELSSWITGERARHDVRTERVPLA
                     SVPRWKRGESTIEHEDGRYFRVVAVSVRAGNREVTGWTQPLFEPVGQGVTAFLSRAFDG
                     VRHVLVAARVEGGFLDTIELGPTVQCTPDNYAHLAPPDRPLFLDTVLRAPADRIRYEAI
                     HSEEGGRFLNAESRYLIVDADESDAPQDPPPGFAWVTPAQLTSLVRHGHYLNVQGRSLL
                     ARLNAAEPAGR"
     gene            30977..31936
                     /locus_tag="RVR_2938"
     CDS             30977..31936
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079:oxidoreductase (Score: 249.1; E-value: 1.2e-75)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="RVR_2938"
                     /product="putative oxidoreductase"
                     /protein_id="BBA97273.1"
                     /transl_table=11
                     /translation="MSTPVRIGVLGCADIAVRRMLPGFAAGPDTEVVAVASRRLAAAER
                     VAERFGGRAVRGYAGLLELDEVDAVYVPLPASLHDRWAEAALDAGKHVLAEKPLTASAA
                     RTGRLLDLARDRGLALMENVLFVHHRRHAAVRRLVADGAIGELRSLHAAFSIPALPDTD
                     IRYRPELGGGALADVGVYPLRAALHFLGPGLEVAGAVLAREDGREVETSGAALLRTREG
                     PTAQVAFGIGQAYLSRYELRGSTGRITVDRAFTPPADLVPVIGLHRGGQREEIRLAPHD
                     QVAAAIAAFAAAVRAGSAPAEETLRQARLLDDVRAHAA"
ORIGIN
        1 tcacccgtgg ccgaagcgga agccgacccc gcgcaccgtg cggatccacg agtagccgcc
       61 gagcttcccc cggagggagc tcacgtgcgt gtctatggtg cggctcgcct cggaccagtc
      121 gtcgtcccac acctccgaca tgagctgccg gcgcgagaag atggcgtccg gcttcgacgc
      181 cagcagggcg agcaggtcga actccttgcg ggtgagttcc accgcccggc cgtgcagcgt
      241 gacctcccgg gtggagaggt tgacctgcaa cgggccgcgg gtgacgacgg ccgcggtcgg
      301 cctggcgtgc gcgcggcgca tcacggcctg gatgcgcgcc agcagctccg agaagccgta
      361 gggcttgccc aggtagtcgt ccagcccggc ctggagcccg atgacgcggt ccatctcggt
      421 gtcgcgcttg ctcacggcga tgatcggcac gtcgcagtgg tcccggaggc gccgggtgat
      481 ctccagcccg tcgagatcgc gcaggtcgag gttgagcacc acgagatccg cctccttcga
      541 cgccgacatc gcgtcgtacc cttcgccgac ggcctgcacc tcgtatccat gtcgacgcag
      601 gtcgcgagta aggacctcgg ccgcttccgt gtcgtcctca accaatagca ggcgcaccta
      661 aacgctcccc gttacgtcgt tcgctgcagg tgagaattcc gcttcgataa gcaaaacggg
      721 taaccgcata cacataacag aagaaaaaga aggtatgggc gtgggaagta gtcggacgtg
      781 gacgttgtca gttcttgact aaaattaacc cacttcatcc gagccgtcaa ctgcatttac
      841 attccgtaaa gaatcagcaa accagtcaac catgccgcac attcgatggt gccacaccgc
      901 cacgccatcc atgggccgac aatccggacg aaggtcgcag gcccgtccca acggagcggt
      961 tcccccaaaa gccgaccgcg ccccgaaccg gtcaccgggg ccgctccgca gaaatgcccc
     1021 caccccgcgg aacgacgtgc accacccgga tcggaacgcc gaccgcggcc tccccgaccg
     1081 cgaacggtga actttcacga accgccgcca ccagatgtga gacggatctc gtttgacagg
     1141 ccccccgtat atccctccga gatcgcgagc ggagaaaata ctcagtcgcg agccacgcta
     1201 tcaagcggca atcgagtggc aagaagtcgc aaccggaata ggtcaggcga cggaaacggc
     1261 attttggcat aatccaccgc atcaccgaaa cgccgggccc gagcgaatcc gccgccggta
     1321 gcaccggtcg gcgggaaagt aaacagtgcg accagcaggc acagggagcg gcgaccggcc
     1381 ggcaccgctc cgggcggccg ttggctgtgg tctacacgtt catcggcgcc ccgccgtgcg
     1441 accgatcggc cgaaaatcga tcacgaagcg tccgaaatgc gagggaagtc gatcggatcc
     1501 ggtcgatcga catatgcagg aaaactccat caaggaaacg caaactctac tacagaaaat
     1561 cgacaccggg cgaacatccc acccttcgga gttcaaccct cgacctacaa cacccgctcc
     1621 gtccgggggc gggacggcga aacacgacac gtcggaacgg ggtcgaccat gacgcacgac
     1681 tcggagcgca cggcacgagt gggctgcgaa ggggtggtgt gccgcggccg gagcggagtg
     1741 cccgggcagg cgcgggcact cgccccggcg gggagcctgc tctgcccggc ctgcgtcctc
     1801 cgcctgaccg ccgatctgcg gcggatgccc cgcctgtacg acgagtgcgc gcggctgctc
     1861 gggggctccg accgtccgcg cgaacgcacc tccggcggcg gctcgccgac cggactcccg
     1921 ttcaacaccg cggcggccga agcgcgttcg gcgctcgtct ccctcctgcg ctcctgggcc
     1981 cggctggtcg tcgaggagcg ggtggtcgcg ccgccccggg acaccgtggc cggcgccgtc
     2041 gcgttcctgg tccggcacgt cgaatggctg gccgcccacg acgccgcggg cgagctgacc
     2101 gaggaggtgg cgcgcgcggt acgccgggca cggcgggtga ccgacccctc ccccggtcgg
     2161 agcgtacgcg tcgggacctg cgtggtggcg gagtgcgggg gcgggctgac ggccgtggcg
     2221 cgcggcgggc gtgacggcgc ggtggtcgag gtccgctgcg ccgcggtcgc ctcgcaccgc
     2281 tggtccggcc gggagtggat ggcgctgggc ggcggcgcgg tggcggcgcc gcgggaggac
     2341 ggcggggagc cggcggagca accggggtcg gtgggacgac cagggccggc tgagcagccg
     2401 gagccgacgg gaccgccgga gcggattgcc gaccgggcgc aggccgtgca gtggttgagc
     2461 ccgcgggacg tctccctgct gtgggggatt ccctccggca gcgtctaccg ccgcgccagc
     2521 gagcagaagt ggcggcggcg cagcggcaaa ggccgcacct tctactggaa ggaggacgtc
     2581 ctgcggtccg tcggagccga cgggggcgac gggggcgacg ggggcgagga atcctgacgc
     2641 tccggcagaa tcgcgcgggc acggcctcct ggccgtgccc gctctcgtcg gtgtccgttc
     2701 tcgtcggtgt ccgttctcgt cggcgtccgt tctcgtgggc gcctgcttcc gtcgcgcgtg
     2761 cgacacggaa gtccgcccgg gtttcccgtt tccggcggga acgcggcccc ggcaccggga
     2821 aatctgcaag cgggcgggcg gcgtcgcatc cgcactccgg ccagggggaa cggccgggga
     2881 acgccgggcg acttgacctt tctctgacat cggcctgtcg ttccttcggg aaagctgaat
     2941 tgacatcccc gacttccccg aagaggatgt tcactatctt cctcagcact gtgccgatcg
     3001 gccggacgga acacgtgccg ggccttttcc ggaatgctcc gcacaggcgg accgccgtgc
     3061 cgtaccggtg acttcggaag cggcggggaa gcgcacgcac ggaattcggt cgccgcggcg
     3121 ccggttcgcc cgccgcctcg cccgcagatt gttccgcagg ttgttccgcc cacggatcgt
     3181 cccgccccgg gctgtttcgc ccgccggccg ttccggccgc cttttcgcag cggcggacgc
     3241 gtgcccgggc cgcccggaaa agccgtcacg acgtcgtcac ggcacgtgcc atcccgttcc
     3301 gccgttccgc gttgcgcggt cccgcgacgg caggcacccc ggatccgacc gtaacgacaa
     3361 ggagatgtgg atgcacagca cgttgatcgt ggcccggatg gaaacccact cggccgcgga
     3421 ggtcgcgaag ctgttcggcg cgttcgacac cacggagatg ccgcaccgga tgggaacccg
     3481 gcgccgccaa ctcttctcgt accgcggcct gtacttccat ctgcaggact tcgacggcga
     3541 ggacggcggc gaacgcatcg aggaggcgaa gaccgacccc cggttcgtcg ccatcagcga
     3601 cgacctgaag ccgctcatca ccgcctacga cccggccacc tggcgctccc ccgccgacgc
     3661 catggcgcac cgcttctacc actgggccgc gcggtgagcg cgccgcacgg ccggcgggtc
     3721 gtcatcaccg gaatcggcgt caccgcgccg cggggcgtgg gcgtcaagga cttctggagc
     3781 ctgctgaccg acggccgcag cgccacccgc cggatcagct tcttcgaccc gtcgcccttc
     3841 cgctcgcagg tcgccgcgga ggtcgacttc gacgccgaac tcctcgggct gagcagccag
     3901 gagatccgac ggatggaccg ggccgcgcag ttcgccgtgg tgacggcgcg cgaggcgatg
     3961 gccgacagcg ggctggactt cggcaccctg gacccgcacc gcaccggcgt gacgatcggc
     4021 agcgcggtcg gcgcgaccac ggggctggac gaggagtacc gcacggtcag cgacagcggc
     4081 cggctcgacc tcgtggacca cacctacgcc gtcccgcacc tctacaacta cctggtgccc
     4141 agctccttcg ccgtcgaggt ggcgtgggcg gtgggcgccg agggcccggc cacggtggtc
     4201 tccaccggct gcacctccgg gctggacgcg gtgggctacg ccaccgagct gatccgcgag
     4261 ggctcggccg acgtgatggt ggccggcgcg gcggacgccc ccatctcacc gatcaccgtc
     4321 gcctgcttcg acgcgatcaa ggcgaccacc ccgcgcaacg acgacccgga gcacgcctcc
     4381 cgccccttcg accggacccg ggacggattc gtcctgggcg agggatcggc cgtcttcgtc
     4441 ctggaggagc tggacagcgc caggcgccgc ggcgcgcaca tctacgccga ggtcgccggc
     4501 tacgccaccc ggtccaacgc cttccacatg acgggcctgc gccccgacgg gcgggagatg
     4561 gccgaggcga tccgcgtcgc cctcgacgag gcccggctcg acccgcacga cgtcgactac
     4621 gtcaacgcgc acggctcggg cacctaccag aacgaccggc acgagaccgc cgccctcaag
     4681 cgcggcctgg gcacgcacgc ccaccgggtg cccgtcagct cgatcaagtc gatggtcggc
     4741 cactcgctgg gcgcgatcgg ctcgatcgag atcgcggcga gcgcgctcgc gatggagcac
     4801 cacgtggtgc cgccgaccgc caacctgcac acgcccgacc ccgagtgcga cctggactac
     4861 gtgccgttga cggcacgcga ctggcggacc gacgccgtgc tcacggtggg cagcggcttc
     4921 ggcggcttcc agagcgcgat ggtgctggcc cgtcccggaa ggagcgagac atgagcggcg
     4981 ccggcgtcag aaccgtggtg accggcctcg gcgtggccgc ccccaacggg tgcggcgtgg
     5041 aggcgtactg ggccgcggtc cgcaagggga ccagcggcat cggccgtgtc tcgcggttcg
     5101 accccgcgca gtacccggcg cggctggcgg gcgagatcac cgacttcgtc gccgaggacc
     5161 acctgccggg gcggctgctg ccgcagaccg accggatgac ccggatcgcc ctggccagtg
     5221 ccgactgggc actcgccgac gcgggcgtcg atccgcggaa cctgcccgag tacggcatgg
     5281 gcgtcatcac ggccagttcc tcgggcggtt tcgagttcgg ccagcgggag ctgcgggcgc
     5341 tgtggagcaa gggcggccgc catgtgagcg cctaccagtc cttcgcctgg ttctacgccg
     5401 tcaacagcgg ccagatctcg atccgcaacg gcatgcgcgg cccgagcggc gtggtcgtca
     5461 gcgaccaggc gggcgggctc gacgcgctcg cccaggcgcg ccgccagatc cgcaagggca
     5521 ccgggctggt gatgtccggc gccgtcgacg cctcgatctg cccgtggggc tgggtcgcgc
     5581 agatggcgag cggccggctg agcacgagcg aggacccgga gcgggcgtac ctgcccttcg
     5641 acgccgccgc gcgcggccac gtgccgggcg agggcggggc gctgctggtc ctggaggacc
     5701 tggagcacgc ccgtgcccgt caggcccgga ccccctacgg cgagatcgcc ggctacggct
     5761 cggccatgga cccgcggccg ggcagcggcc gcccgcccac gctggtcagg gcgatcgaac
     5821 tggcgctggc cgacgccggc gcggccccgg aggacatcga cgtggtgttc gccgacgcgg
     5881 ccgcggtgcc cgcgctggac cggatcgagg cggaggccgt ctcccgggtg ttcggtccgc
     5941 ggggcgtgcc ggtcaccgcg cccaagacca tgaccggacg cctctactcg ggcgccgcgc
     6001 cgctggacgt ggccgccgcg ctgctcgcgc tgcgcgacca ggtgatcccg ccctccgtcg
     6061 gggtgacccc cgaccccggg tacgccctgg acctggtggt cggcgcggag cgcgccgcgc
     6121 cggtccgctc cgccctggtg gtcgcccgcg gccacggcgg cttcaactcc gcgctggtgg
     6181 tgcgcgccgt ccggacgtga cgcccagggg gaggccggcc cggccggcgg ccggacaccg
     6241 gttccgacgg tgcccgcccg accccgcgac gcctccccgg ttcagggcct gtccggcgga
     6301 tcgtgccggt cgggctcgcg gcgtgcgatc cagcgcatct gacgccgcac gctgatccgc
     6361 cggggatgac cggacagccc taaccgagga gaaaggacaa cccatcatgt ctgcccacga
     6421 gttcaccgtc gccgacctga aacgcatcct gcgggaggga gccggcgcgg acgagggcgt
     6481 ggatctcgac ggagacatcc tcgacaccga cttcgagtcg ctcggctacg actcgctggc
     6541 catgctggag accggcagcc gcatcgagcg cgagttcggc gtcacgctgg acgacgaggt
     6601 cctgaccgag gcggagacgc cacgcgccct gatcgaggcc gtcaaccacg tggtggtgcg
     6661 gtccggcgcc gtctgatccc cgaccgcacc gccaggtcgc ggtcccgccc cgggtcggcg
     6721 gcaggtccgc cgtccgcacc gcaccccggt ccgcgccccg gtccgcgcca tcgcgcccgc
     6781 gccgcagccc cggcacaccg caccccgtga gtccgcaggg ccgcacgccc gcggcgccgc
     6841 accccacagg gccgcacccc cgcccgccgc aggaccgtac gcccgcaccg ccgtgcccac
     6901 gtgcccggcg tcgatcaccg acgagtcagg agagagcatg acggagcagc atccgaaggt
     6961 cgccgtcgtc accggcgcca ccagcggcat cggcctggcg accgccaggc tgctggcgcg
     7021 ccgggaccac cgcgtgttcc tctgcgcccg cacgcaggag agcgtgacgc gtaccgtcaa
     7081 ggaactcgtc gacgagggac tcgacgtcga cggcgcgccc tgcgacgtgc gctccgcggc
     7141 ggacgtccgg cgcttcgtgc ggcaggccgt cgaccgcttc ggcccgatcg acgtgctggt
     7201 caacaacgcc ggccggtccg gcggcggggt caccgccgac atcaccgacg agctgtggtc
     7261 cgacgtcatc gacaccaacc tcaacagcgt cttccggatg acccgcgagg tgctcaccgc
     7321 cggcggcatg cggcggcgcg gcagcgcccg catcgtcaac atcgcctcga ccgccgggaa
     7381 gcagggcgtg gtgctcggcg cgccgtactc cgcctccaag cacggcgtcg tcggcttcac
     7441 caaggcgctc ggcaacgagc tggcgccgac cgggatcacc gtgaacgcgg tctgccccgg
     7501 ctacgtcgag acgccgatgg cacagcgcgt ccgccagggc tacgcggccg cctacgacac
     7561 gagcgaggac gcgatcctgg agaggttcca ggccaagatc ccgctcggcc gctactcgac
     7621 ccccgaggag gtcgcgggcc tggtcggcta cctggtctcc gacaccgccg cctccatcac
     7681 cgcgcaggcg ctgaacgtct gcggcggtct gggcaacttc tgacatccgc gggagaagag
     7741 gaccgatgac gaaccgccag gtcgagcacg agatcaccgt cgccgcaccg gccgccgccg
     7801 tctaccggct gctggccgag gtggagaact ggccccggat cttcccgccc accatccacg
     7861 tcgagcacct ggagcgcggc gcggacgacg agcggatcag gatctgggcc accgcgaacg
     7921 gcggggtcaa gagctggacg tcccaccgcg cgctggaccc gcgcacgctg cggatcgcct
     7981 tccggcagga ggtctccagc ccgccggtcg ccgcgatggg cggcacctgg atcgtggaac
     8041 cgctgtccga cgcggcgtcc cgggtacggc tgctgcacga ctaccgggcg gtcgacgacg
     8101 accccgaggg cctggcgtgg atcgacgagg ccgtcgaccg caactcccgc agcgagctgg
     8161 ccgccctgaa gcagaacgtc gaacgggccc acgcggccga ggagatcacc ttctccttcg
     8221 aggacaccgt gcgggtgcgg ggcagggcgg cggacgtcta cgacttcgtc aacgaggccg
     8281 gccagtgggc gcggcgcctg ccgcacgtgg cgagcgtccg cctggaggag gagaccccgg
     8341 ggctccaggt gctggagatg gacaccctcg cgcaggacgg ctccacgcac accaccaagt
     8401 cgtaccgggt gaccttcccg caccgcggga tcgcgtacaa gcaggtcacc ctgcccgccc
     8461 tgatggccct gcacaccggg tactggacct tcgccgagga cgagcagggg gtcgccgcca
     8521 cctcgcggca cacggtggtc ctcgacaccg gcaacatcgc ccgggtgctc gggccgcagg
     8581 cgagcgtcgc cgacgcccgg ggctacgtcc ggcgcgcgct gagcaccaac agccgcatca
     8641 ccctcgcgca cgcgaaggac tacgcggagg gcaggcgttg accgggcacg cgcgcgcggc
     8701 ggacaccgac gtggtcgtcg tcggcgcggg accggtcggg ctgatgctcg ccggggagct
     8761 gcgggccggc ggggcgcggg tgaccgtact ggagcggctg gcggctccga ccggggagtc
     8821 gcgggcgtcg accctgcacg cccgcaccat ggagatcctg gacgagcgcg ggctgctcga
     8881 cgcgtggggc acggtgcccc gcgccgcggg cggccacttc ggcggcatcg ccctcgactt
     8941 cggcgggctg gacagccggt acgcgggcca gtggaaggtg ccgcagaccc gtaccgagca
     9001 cctgctgggc gaacgggcgg tccgcctcgg cgcggtcgtc cggcgcgggc acgcgctcgt
     9061 cggcctgcgc cagaccgggt ccggggtcga ggccgagacg gagggtcccg cgggccggtc
     9121 ccggatcagg gccgcctacc tggtggggtg cgacggcgag gacagcaccg tacgccggct
     9181 ggcgggcttc gccttccccg gcacggacgc gacgcgggaa ctgctccgcg ccgacatcgc
     9241 cgggatcgac gtgcccgacc gccggttcga gcgccacgag cacggcctgg ccatcgccca
     9301 ccggcggccc gacgggatca cccgggtgat ggtgcaccag ttcgggcggg ccgccgcccc
     9361 gcgcgccgcg gcgcccggga tcgcggaggt cacgtccgtg tgggcgaagg tcaccgggga
     9421 ggacatcggc gcgggcaccc cggtctgggt cgacgcgttc ggcaacgccc gccggcaggc
     9481 cgagcggtac cgcgccggcc gggtcctgct cgccggggac gccgcccacg cgcagatgcc
     9541 ggtcggcggc caggccctca acctgggcct ccaggacgcc gtgaacctgg gctggaagct
     9601 cgcggcacag gtacgcggcc gggcgccgca gggcctcctc gacagctacc acgacgagcg
     9661 gcacgccgtc ggcagccggg tgctgaccaa catcgaggcc caggccacgc tgctgctggg
     9721 cggccccgag gtggagccgc tgcgcgcggt cgtgaccgac ctgctcggcc acgacgaagt
     9781 ggtcggccac ctggccggca tgatcagcgg cctggacgtg cgctaccccg tcggggacga
     9841 cggtccgcga ggcggccacc cgctgctcgg cggccgggtc ccgcactggg agctggccac
     9901 cgcctccggc gcgtccagca ccacggaact gctgcgcgcc ggccgcggcg tgctgctcga
     9961 cctggccggc tgcctgccgc ccggcgcggg cgccggctgg gcggaccggg tccgcacggt
    10021 gacggccgcc ccggcgcccg ccgacggagc accgtcccgc cccggcacgg cggccgtccc
    10081 cgcggtgctg atccgccccg acgggcacgt cgtctggtgc gccgacggca cggccggccc
    10141 ggaggccgcg ctgcgccgct ggttcggcga cccgcacgcg tgacgcggcc gccgcgcggg
    10201 cgggcggcgt acggctggcc gacgggcggc ggaccgccgg cggacggtcc ggcggacgac
    10261 ccggcagccg aacggccggc ggtcccgcgc ggcggcgccg cacccgaacc caggatctga
    10321 acaggaggcc cctgatggat gctcccttcg acgccgaggt cgtggtcgtc ggcgccgggc
    10381 cgaccggcct catgctcgcc ggggaactgc tcctcgccgg agtccgggtc accgtgctcg
    10441 accggctcgc cgaaccgacc accgagtccc gcgggttggg cttcaccccc aggaccatgg
    10501 aggtgttcgc gcagcgcggc ctggtggacc ggttcgacgg actggacatc ccgctccaga
    10561 ccaccacccg cgggcacttc ggcgggctgc cgctggactt cggggtgttc cccgaggccc
    10621 atccggccgt cgcgaacctg ccccagttcc acaccgagtc gatgctgcgc ggctgggtcg
    10681 ccgaactcgg ctgcgacctg cgccgcggcc acaccgtgac gggcctcgcc gacaccggcg
    10741 aggccgtgga ggtcacggtc gaacgccccg gcggcccgcg ggtcctgcgc gcccggtacg
    10801 tggtcggctg cgacggcggc cgcagcacgg tgcgcgggct ggccggcttc gccttccccg
    10861 gcacgcccgc caccctcgaa ctcttcctcg cggacgtccg aggctgcggc ctgcggccgc
    10921 gcttcatcgg cgagtggctg cccggcgggg tcgccatggc ggcgcccatc ggtgacggga
    10981 tcgaccgggt ggtggtgtgc gagcgcgacg cgcccccgcg gcggcgcacc cggcctgtgg
    11041 cgtacgcgga ggtcgcggcc ggctggcggc ggctgaccgg ggaggacatc agccacggcg
    11101 agccgctgtg ggtgagcgcc ttcggcgacg ccacccggct ggcgacggag taccgcaggg
    11161 gccgggtgct gctggccggg gacgccgcgc acgtccacct cccggcgggc ggcctcggga
    11221 tgaacaccgg tatccaggac gccttcaacc tcggctggaa gctcgccgcg gtggtgcgcg
    11281 gccacgcccc ggacgcgctg ctcgacacgt atcacgacga acggcacgcc gtgggcgagc
    11341 ggctgctcga caccacccgc gcccaggggc tgctcttcct gggcggctcg gtgatgcagc
    11401 cgctgcgcga cgtgctgggc gagctgacgg gccacgaggc ggtgcaccgg cggctggccg
    11461 gcacggtcag cgggctcggc atccgctacc cgatgggccc gggcggcggt gacgcacggc
    11521 agggccggcc gggcggcgat ccgccggccg gcggccaccc gctgctcggg ctgcggatgc
    11581 cggacctgga gatcgccggc gggacgggca ccacgtcggt cttcgcgctg ctgcgcgcgg
    11641 cacgcggcct cctgctggac ctcgcccacg acgcgtccct gcgccgggcc gcccggccgt
    11701 gggccgaccg ggtcgacgtg gtggccgccg aaccggccgc ggactccccg ctgccgcggg
    11761 tggacgcggt gctggtgcgg cccgacggac acgtggcctg ggccgcgccc ggcgggcgcg
    11821 aggacctggc cgacgcgatg acccgctggt tcggcgcccc gcgcgccgcg gcggcctgag
    11881 gcggaggagg acccccatgg cacggacggc acaggaggcg gacgcgctgc gccggctcgc
    11941 ggaccggatg gacgtacggg aactggtcga ccgctacctg gcggggctgg acgaggggcg
    12001 cttcgacgac acctgggcac ggtcggtctt caccgaggac ggccggttcg aggtgccgac
    12061 gggcggtcac gacggcgtgg ccggcatggc ggaggccacc gccgcgatga tcggcaggtg
    12121 gcggagcacc caccacctgg ccgcgggcca cctcgtcgag atcgacgggg accgggcgcg
    12181 ggtgcggggc agcctggtcg tcacccacct ctacccccct ggggcggtcg tgcgggagcc
    12241 ggcgccgcgg gagtccgggc cgcggaagcc cgggccacgg gagtccgggc tgcaggacgc
    12301 gcccgggcgg gtcggagcgc cggacgcgcc cggggcgccg gagccgttcc aggtcggcga
    12361 ccgcttcgag ggcgccgcgg tgcggaccgg cgccggctgg cgcttcgcgc ggctcgcgtt
    12421 cgaggtggtc tggacccgcg gcaccccgcc ggggcgcgtc gagttccccc acccctgacc
    12481 tctcccggat gacgtccgcg acggccggca tccacgacag cgaggacagc cacatgcgca
    12541 ttctcatcgc ggtcgcaccg ctgaccgccc atctgtaccc cagcgtcccg ctggcgtggg
    12601 cgctccagac cgccggacac gacgtacggg tcgcgagcaa cagcggtctg gtcgagcaga
    12661 tcaccgccgc cggcctgacc gcggtcggcc tcggcgaacg caccctgccg cccgcgcccg
    12721 tcaccgacga ggagctggac cgcttcagcg acgcgctcgc cttcgaggcc ggctccgacg
    12781 ccgaccagct ctggcgggcc atccgcttct acctggtggc cgcgcacgcc cggtaccacc
    12841 cggaccggga gggccggcag gaaccggccg acaacctggt cgaggccgcg cggagctggc
    12901 ggccggacct ggtcgtctgg gacccggcgt gtccggcggc gtcggtcgcc gcccgcgtgt
    12961 gcggggcggc gtcggcccgg atgatgtggg gcccggacta cctcggctgg atccgcggac
    13021 gcctgctgga acgcatggcc gacccggcgt ccggggtgcg cccggacacc gatccgctgg
    13081 cggcgaacct ggcgccggtg ttcgagcggt acggccacgg cttctccgag gacctgctct
    13141 tcggcgactt cacggtggac ccgatcccct cgcggttgcc gagacacccc ggcgtgcgcc
    13201 gcgttccgat gcgctgggtg ccctacaccg gggcggcgcc ggtaccgccg tggctgtccc
    13261 ggccgccgtc gcggccccgg gtgtgcctgt cgctgggcgt caccgggcgc accgtccagg
    13321 agggccggga cgcgcgcgtg gcggccgccc tggaggccgc ggccggcatg gacgtcgagg
    13381 tggtcgccac cgtcaacgcc tcgcagctcg gcccggacac gcgcgtgccc gacaacgtgc
    13441 ggctgcacga ctacgtcccg ctcacccagg tgatgccgac ctgctcggcg atcgtccacc
    13501 acggcgggtt cggcacgttc ttcgcggcgg ccgcgcaccg ggtgccccag atgatcgtca
    13561 ccgacgagct gggcagctcg ctgtccagct cccgctacct gacgtccaag ggcgccggag
    13621 tggccctgcc cggcgacggc ctgaccgccg atcggttggg cgaggagctg tccagggtgc
    13681 tcaccgagcc gtccttccgc gagggcgccg acgcggtgtt cgccgacctg gcctccgccc
    13741 cccgcccgac cgagatcgtg ccggtcctgg agcggatggc cgcccggcac cggaaggggg
    13801 cctgaggccg tggacgtcgt cgagaccacc gtgccgggcg cgttcgtgtt cacgccgcgg
    13861 cagatccgcg acgagcgggg cgcgttcttc gaggcgttcc gtgacgacca ggtcgaggcg
    13921 gccaccggcc gcccgttccg accggagcag atcaactact ccgtctcccg gcgcaacacc
    13981 ctgcgcggca tccacggggt ggccgtaccg ccggggcagg cgaagtacgt cacctgcgtc
    14041 cgcggggcgc tgcgcgacat cgtggtcgac ctgcgggtcg gctcccccac cttcggcgcc
    14101 caccacgtga cgtcgctgga cgccgggtcc gcgcggtgcg tgtacgtgcc ggacggggtg
    14161 gggcacggat tcctctcgct caccgacgac gcctgcatct gctacgtggt ctccacgcgg
    14221 cacgtgcccg gcacgcagat cgacatcaac ccgctcgacc ccgacctcgc gctgccgtgg
    14281 gagttcgacg agccgccgct gatgtcggag aaggacgcga cggcacccgg cgtgcacgcg
    14341 gcgctcgccg ccgggtcgct cgcgaactgg cacgacgtgc gctgaagccg tcccgtgggc
    14401 cggacgcgcc ccgagccgcc cccgaaccgg acggcccgcg gccgcgcgac ccggccgtac
    14461 cacgcccgga cgccgggccg gcctcccccg cacgcggcgg cccgtccggc gaagtccctg
    14521 gagaaggtgg acaaccgaca tgcccgatac gcactttgcg gccgacccgg cccagacccc
    14581 ggtgggtgtc tggaccggct cggtccgcca cgacgaccag accgacccct acaccatttc
    14641 cttcgcaccg gacgggacga tcgcgctgcg cacccccgtc acggtcggca ccgggacgtg
    14701 ggtcgccggc ccgccggggc ggttctccta cgaactcacc gaggtcttca cgccggcgag
    14761 cggccacgcg ggccacctgg aggcccacgt cgagggccgg ctcgacggat cggcgcacag
    14821 cggcaccggc accgccagga tctacacccc cgacggggtg ctggtgcaca ccaccacggc
    14881 ggagtccgcc ggtgagcggg tcggcgaccg gccggccgcc tggcacgccc tcgtgggcct
    14941 gggcgcgccg atccgcggac gcacgctcca ccgcggcgac gacgggttcg acgaggcggt
    15001 gtcccgccgg cccggcaacg gagggcgtcc ggaggcggtc gtggtcgccg cggacgccga
    15061 cgacgtggcc gccgcggtcc ggttcgccgc cgaggcgcgc cgcgcggtcg cggtggagcc
    15121 cggcgggccg gcgcccgccg acggcgcggt gctggtggtg accgcggacc tgacggaact
    15181 ggcggtcgat cagcgggccg cgactgcccg gatcggggcg ggtctgcggt ggggcgaggt
    15241 gctcgcggcg gccgccgagc acggtctcgc cccgctgcgc gacctgccgg cggacgccgg
    15301 tgcggcggac tacctgaccg gggacgcgtc ctgggcccgc ggcgcggccg cccccgcctc
    15361 gcacgacgtc cgctccctcg aactggtcac cgccgacggc ctggtccgca ccacctcgcc
    15421 cacccgggag cccgacctgt tctgggcggt gcgcggcggc gcgagcggcc tcggcgtgct
    15481 gaccggcgcc gagatcgggc tggcgccggc gctccccgcc gacggcggcg agcccgcggg
    15541 cgcccggccg gcggccccgc acccgcaccc tcacccgaac gcgaggcggc tcgccgaact
    15601 gaaggccgcg tacgacccgc acgacctgtt ccgtacccac cacagcaccc cgccgtcgcc
    15661 gacggcgggc gagaggggaa ccaccggcat gccgctttcc acggacccgc agtcggcgat
    15721 ggccgaactc gtcaaactgg ccggagcgca ggccgcccgg gccgacgccg agcgcaaggt
    15781 gagcccggag gtgatccggg cggtggtgga cgccgggttc gcccggtggc gggtgccggc
    15841 ccgctgggga ggggccgagc gcagccacgc cgagctgacc gccgcggtgg cccggctggg
    15901 cgaggagtgc tcgtcgaccg cctggctggc cagtgtcgcc gcctactccg cccgctacgt
    15961 ggcctgcatg ccggagcagg gccaggccga catctgggcg gacggccccg acgtgctggc
    16021 ggcgatcgtc ttcaagccgc tgggcacggt cgtcccggtg gacggcgggt tccggctgtc
    16081 cggttcctgg acctacgtca gcggcgtcga ccacttcgac tgggccctgc tgaccggccc
    16141 cggccccggc ccgagcgcgg ccgggcagcc gatgcggctg ttcgcggtgc cgcggcggga
    16201 ctacgcctac gaggacacct ggtcctccct cggcatgcgg gctaccggca gccacacgct
    16261 cgtcctggac gacgtcttcg tgcccgagca ccgcacctgc ctgcgcgagg acgcgatgcg
    16321 gggcgcgctg gtgggcctgc ccgggtacac ccagttgtcg aaccccgccg tgagcgggct
    16381 gatgttcgtc tcccccgtgc tcggcgccgc gcgcgccgcc ttggcggtcg cggcgcagtc
    16441 cgtggcggtc gcccccaccg ggccgcggac ccacgccggc cagccctacc aggtggactt
    16501 cgcccgggcc gccggggaga tcgacgcggc ccaactgctg ctggagcggg ccgccgccgt
    16561 cgcggacggc gacgcggtgc cgccggagct cgcgcgccgc aaccgccggg actgcgcgct
    16621 ggcgctccag atgctgatcg gcgcggtcga ccggctgctg cggatcggcg gcacccgggc
    16681 ccaggacgac gggcacccgc tccagcgcta ctggcgggac gtgcgctcgg tctccagtca
    16741 cgcggtgatg cagttcgagc ccgcggggct cgccttcacc gaaggtctcg tcggacagcc
    16801 ctgaagagga cggccatgat cctggtaacc ggagccaccg gccatgtcgg caggccgctg
    16861 gtggaggagt tgtcggcggc cggccggaag gtccgggcgc tcagccgcga cccggcgcgg
    16921 gccggcctgc ccgccggggt cgaggtggcc gccacctccg acctccccct cgacggcgtc
    16981 acgtccgtct tcctcgtgac ggccgccttc ccggacggct gcgcggagcc gatcgcccgg
    17041 atgaaggcgg ccggggtgcg ccgcatcgtc gccctgtcgt cctactcggt cctcgacgac
    17101 gatccccgga acatgatcgg tgtcaggcac cgcgagctgg aacgccggat cgaggagacc
    17161 ggcgccgagt ggaccttcct gcggcccgcc ggggggttcg cggcgaccgc cctggagtgg
    17221 gccgcgcgga tccgcgccga cggcgtcgcc cgctcgccgt tcgcggacgc gcggaccgcc
    17281 ccggtgcacg aacgggacat cgcggccgtg gccgcccgcg cgctgctcac cgacgacctg
    17341 gtgggcgagg caccgctgtt cagcgggccg gagtcgctca gctacgccga ccgggcgcgg
    17401 atcatcggcg aagtggccgg ccggccggtc cgcttcgagg agctcacccc cgaccaggcc
    17461 cggcaggagt ggctgcgggc cggtgtcccc ccgcacgccg tggaggcacg gctgcggatg
    17521 ttcgcccggc tggtcgggca cccgcacgag atctcaccgg tcgaccccta cctcggcagg
    17581 cccgggctga gcttcgcccg gtgggcggcc gaccacatcg actcgttccg agaggcggcg
    17641 tcatgattct ggtaaccggt gcccggggca acgtgggcgg cgagttgctg cggcaactga
    17701 gcgcgggggg gcacgccgtc cgcgcgctca cccgggacgc ggcgcgggcc gggctcccgg
    17761 ccggtgcgga cgtggccgag ggcgacttcg gcacggcggg gtcgctggcc gcggcgctcg
    17821 ccggggcgga ctccctgttc ctgatgacct cgggccacga gaccgcggtg ctccgggagg
    17881 cggtgcgcgc cggggtacgg cgggtggtgc tgctgtccag catggccgcg acgacccggc
    17941 cgcagtccct catcggcagg atgcaccggg aggcggagct cgccgtcgag gcgtccgggg
    18001 tggagtggac gttcctgcga ccgggccagt tcgcctccaa cacgctggcg tggcggtccc
    18061 agctcgcggc gggcgacgtc gtgcgcacgc cgttcgcgga cgtggccctg ccggccgtcc
    18121 accccggcga catcgcggcg gtggcccgca ccgcgctcac ccggaacggg cacgccggac
    18181 aggcgtaccc gctcagcggg cccgagccgg tcacacccgt cgagcaggtg gcggcggtcg
    18241 gcgaggcgat cggccggaag ctgcgccacg aggagatcgg cccggagcag gccgcggcgg
    18301 cgatggccgc gcacatgccg gccccgatcg tggcggccag cctggagttc ctcggcagcc
    18361 ccaccccgga ggagacccgg ccggtgccca ccgtcgagaa ggtgaccggg acgccggcgc
    18421 ggaccttcgc gcagtgggcg cgcgacaacg ccgacggatt ccgctgacac ctggtcacga
    18481 gggagggaac gcgcgtgaga gcactggtgc ccgccgcggc ggccgcatcc cggggggcgc
    18541 ggccatgctg acccagcgcg gcttccgcga cgtcctggga tgcttcagca ccggagtggt
    18601 gctggtgacc gcggaccatg acggcgcgcc ggtcggcatg gcggtgaact ccttcacctc
    18661 cgtgtcgctg gacccgccgc tgatcgcctt ctgcgtcgcg ctgacctcca ccacgtggcc
    18721 gctcatccgg gcgaccggcg gcttcgcgat caccatcctc agcgacacgc aggaggacgt
    18781 ctgccgggtc ttctcggccc acggcgcgga ccggttcgcc gacggcgact ggacccggac
    18841 gcccgccggg cgcgccgtga cggccgacgg gctcggctgg ctggactgcc ggatcaggac
    18901 ggtccaggtc gaaggggacc acgaactggt catcgcccag gcgctggact ggtccatcgg
    18961 ggccgacgcc cggccgttga tcttccactc gggccgctac gccagcctca gggagcgttc
    19021 ggatgcggaa tgacaccgcc ggccggccgg cgcgcccctt cgcacggcgg gccgcgggcc
    19081 ccgcggccga cgccacgacg gccgacgcca cgacggccga cgccacgacg gaaccacagg
    19141 aggtgtcctc atgaccggag tgatcgtcgc gggcgccggc ccgaccgggc tgatgctcgc
    19201 ctgcgaactg cgactggccg gggtggacgt cctggtcgtg gagcggctcg cggagccgaa
    19261 cggccggtcg cgggccggcg gcctgcacgc ccggagcgtg gagctgttcg accagcgcgg
    19321 gatcgcggag cggttcgtcg cggcgggccg gcccgggccg ttcgcgcact tctcgttcat
    19381 cccgctggac atccgggacc tgccgacgcg gttcccgtac gcgctggcca tcccccaggc
    19441 ccaggtcgaa cggctgctgg aggagcgggc ggtggagctg ggcgtacggg tgcgccggtc
    19501 cgccgaggtg gtcgacctgc gccaggacgc caccggggtg gacgtgcgga tcgccggtga
    19561 gcggggcgtc gagtggctgc gcgccggcta cctggtgggc tgcgacggcg gccgcggcgc
    19621 ggtgcgcaag ctcgccggca tcgggctgtc cggcacaccg gccacgctca ccgcgctgct
    19681 cggcgacgtg gtgctcaccg acccgcccgc cgacgtggtc ttcggcgccg acagccgccg
    19741 ggagcacggg tccgtgatga tcttcccggc cgacgtcccc ggcctgcacc gggtgatcac
    19801 catggagttc ggcaaggtga cggagcggga ctccccggtg accctggaca cgctgcgcca
    19861 ggcgtgcctc gggctcgggg gcaccgactt cggcatgcac gacccgcact ggctgagcag
    19921 cttcagcgac gccgcccggc aggcggaccg gtaccgcgag gggcgggtcc tgctggccgg
    19981 ggacgcggcg cacgtccact tcccctccag cgggcagggc atgaacctgg ggctccagga
    20041 cgccgtcaac ctcggctgga agctcgccgc ggtcgcccgc gggcaggccc cggacgagct
    20101 gctggacagt tacggcgccg agcggcgccc ggccgtcgag cggatgctcg acagcacccg
    20161 ggcgcagacc gccctgtggc gcccggacgc ccagatcgag gcgctgcgcg gggtgttcgg
    20221 cgccctggtc ggctccgagg aggtcaaccg cgcgctgggc ggcacctgca cccagctcga
    20281 cgtccgctac cccctgggcg acggttcgcc ggccctcggc cgccggatgc ccgacctcga
    20341 catcacgtcg ccctccgggc acacccgcgt cttcgagtcg ctgcacgcgg ggcgcccggt
    20401 cctgctcgac ctcggcggcc ggccgggcct cagggccgcc cttgagggct ggacggaccg
    20461 ggtggacctg gtcgaggcgc ggtgcgagga cgacttctgg agctacccgg tgatcggcga
    20521 cgtcccggcc gccacggccg tgctgatccg cccggacggc cacgtcgcct gggtcgcgcc
    20581 cgccgcgccc gccgcggacg ccgtcgcgtc ggacgcctcc gccgcgtccc tcgggtccgc
    20641 gctcacccgg tggttcggcc ccgcccgcgg ccactgaccc gtacctgtac ccgttcccgt
    20701 tcccgtatcc gtatccgtat ccgtaccagg agacccgccg cgaccggccc gcgcgccggg
    20761 acgtgcacag accggcaccg cccacgttga tcggagaatc gcgtgtccaa ggacgaactg
    20821 acgccctccc aggaagcccc cgcgctgccc ccggagttcg ccacgctgat gcggctcggc
    20881 gacctggtga ccccgatggc gctgcgggtg gccgcccgcc tgcggctggt cgaccacctg
    20941 cgcggcggcg tccacgacgt cgagtcgctc gcgaaggcga ccggctccca ccagcaggcc
    21001 ctcggccggc tgatccgcca cctggtcgcc gtcgaggtgc tggaggagtc cgagccgggc
    21061 cactacacgc ccaccgcgct cggcgaactg ctggcccacg accacccggt gacccaggtg
    21121 ggatggctgg acccgaccca catgatcggg cgcgcggacc tcgcgctcat ccacctcttc
    21181 gaagccgtcc gcgacggccg ccccgtctac gagcggcagt acggcaagga gttctgggag
    21241 gacgtctcgg cggacccggt gctcagcgcc accttctacg acctgatggc gcacggccag
    21301 aagcacatct tcggcctggc ggtcgcgcag cacgactgga gcggcgcacg ccacctgctc
    21361 gacgtgggcg gcggcgacgg ggacctgatc gccaccctcc tcgcggcgga acccggcatc
    21421 cgcggcacgc tggtggagct gcccggtccg gcggcccggg cgcggacgaa gttcgaggag
    21481 gccgggctgg ccggccgggc cgaggtggtg gcgggcagct tcttcgaccc gctgccggtg
    21541 acggccgacg tgatcgcgct gtccttcgtc ctgcacaact ggtcggacca ggacgcggtg
    21601 cggatcctgc gcaactgcgc gcaggcgctg gagcccggcg ggtccctgct gctcatcgag
    21661 tgcgccgagc agtcgccgtc ggcgccggac ccggccttca ccagcggcga cctgcggatg
    21721 atggtctact tcgaggggcg cgaacgcacc cacgaccagt ggcgggagct cgcgaccgcg
    21781 gccggcatga ggatcgactc ggtgtccggc gcgctcgcgt acggcgcccg cgtgctcacc
    21841 ctcgtgaagg cgtcctcctg accggccgtc acctccaccg tcacctccat ctcgcggtgc
    21901 gctcgcccgg caccgccggg ccgcaccggc cacgcacacc aaccagccgg accgcgggac
    21961 cgcgcccccg cggccggatc gcgcaccggc gcggcggaag gggaaccact gtggcgcacg
    22021 acgaggtccg ggcggcagcc gcggacgacc gcggacacgt catccgactc gtgttcggaa
    22081 acctggcggc gcgtgccctg cacgcggccg tcgagctgag gatcgtcgag ctgatcgggg
    22141 acgggcagcg gtccgccgcc gacctcgccg cgcgggccgg cacggacccg cagtccacgc
    22201 tgcggctgct gcgcgcgctg accgccctgg gcctgctccg cgagcccgta ccgggcacct
    22261 tctcggccac gccggccggc gcgctcctcg acccgggcgc cccgggctcg atggccgcgc
    22321 tggtgctctc ctccgcgacc atggagcaga tgatgcggcc cggttgggac tacctggccg
    22381 acagcgtccg caccggggac acctcgttcg agaaggtctt cgacaaggac ttcttcagcc
    22441 acctgcggga ccacccggag cgctccgcgc gcttcaacga ggcgatgagc caggccaccc
    22501 gcagcaccgc cgcggtgctg ccgggctcct tcgacttcgg ccgcttcggc acggtcgccg
    22561 acgtcggggg cggcgacggc accctgctcg ccgccgtcct gcgggagcac acctcgctga
    22621 ccggcatcct ccacgacacc gaggagggcc tcgcgcaggc gccggagacg ctgcggcgcg
    22681 acgggctcgc ggaccgctgc tccctggtgc cgggggactt cttcacgtcg gtgcccgaag
    22741 gcgccgacgt ctatctcgtc aagagcatcc tgcacgactg gccggacgac cggtgcgcca
    22801 cgatcctcgg ccactgccgc gaggtgctgc cggccggcgg gcgggtgctg atcgtggaac
    22861 ccgtgctggc ggaggcggtc gatcccggcg ccgtggggct ctacctcggc gacctcaaca
    22921 tgctggtgaa ctggggcggc cgggagcgca cccggacgga gttcgacgcg gtgtgccacc
    22981 gggcgggcct ggagatcgtg tcggtgacgc ccctcgcggg ccccggcttc tccctgatcg
    23041 aggcacgggc cgtctgaccg cgggcacctc ccctttcccc gccttcgcgc ccccgcattc
    23101 cggtcggcac gataaaccgg aggaccgatc cgggaattcc catttccccg accggcaccg
    23161 gccgttggcg taaggcgatc ggagtttctc ggctccttga cagccaatgg gccgggctga
    23221 cagggtccgg gcgtcggtcc ggccccgctc ggagccggac cgatcggccc gggaaatcgc
    23281 gacgcatatt acggagtcac tccatgacag cacctctcga ccgcgccccg ctttcggtcg
    23341 gcgaactcga ccccgcacgg tacggacagg tcatcgggcc cggcgacgcc ggatacgacg
    23401 cggcacgcac cgtctacgcc ggcgacgtcg accgcaggcc cgccgtcgtc ctgcgccccg
    23461 gcgacgccga gcaggtcgcg cacgtcgtcg ccctggcgcg ggagaccggt ctggaactgg
    23521 ccgtccgcgg cggcggccac agcgcggccg ggcacagcgt gtgcgagggc ggcatcgtcc
    23581 tggacctggc aggcatgcgg ggactggaga tcgacgccga ggcccgtacc gcctgggccg
    23641 aggccggcgt cttagccggc gagtacaccg aggccgccgc gcggcacggg ctcgcgaccg
    23701 ggttcggcga cagcgccgcg gtcggggtcg cgggcatcac gctgggcggc ggcatcggct
    23761 acctgacccg caagcacggc atgaccgccg acgacctgct ggccgcggag atcgtcacgg
    23821 ccgacggggc gctgctgtcg gtggacgagc ggcaccaccc ggacctgttc tgggcgatcc
    23881 gcggcggtgg cggcaacttc ggggtggcga cccggctgaa gctgcggctg cacgaactcg
    23941 acggcgtgta cggcgggatg atggtcaccc cggtgacccc ggagatcctc gaagccttcg
    24001 tcgccgaggc cgaggccgcc cccgacgaac tgtccaccat cgtgaacgtg tggaccgcgc
    24061 cccggttccc cttcatcccg aaggagtacc acggcaggcc ggtcatcctc gcgatgctgt
    24121 gctacgccgg ccccgccgag gagggggaga aggtcgtcga ccggttccgg gcgatcgtgc
    24181 cgccgctggc cgacctggtg aaggccatgc cgtaccccgg gatgttcccg ccggtgaacc
    24241 ccgacgagca cccgatctcc gcggcgcgca acatgttcat cgaccgggtc gacagggcca
    24301 ccgccgagac catcgtggag cggatcagca cctcgaccgc gcggatggcc tcggcgcaac
    24361 tgcgggtgct cggcggcgcc ttggcgcggg tcccgtccga ggccaccgcc ttcgcccacc
    24421 ggcgcagccg gatcatggcc cacctggccg ccgtccacac cggcgagccc gacgtgcacg
    24481 aggcgtgggt cgaggagttc gcggccgcca tccggcagtc ggactccggc tcctacgcca
    24541 acttcgtggc ggccgcggac gcggaacagg tccaaaacgc gatgtatccc ggcgccacgt
    24601 gggaacggct cacccgggtc aaggcggaat acgacccgtc caacctgttc cgctccaacc
    24661 acaacattcc gccggcgacc gcgcgcgggt aatcaggaac cggagggaac ggaaaggaaa
    24721 ggggaaggaa cggcaggatc gggcgcgggc gaaaaggggc ggcggtcata caccgacggc
    24781 tttcgacgcc cgccggaaac gtgcccggca cgtgagatcg agcggtcctc cgaaggccgc
    24841 ggttcccctc agtcagcccc cgcccgtgcc ggcgggggct ccgtcatgtc cgcgcgaggc
    24901 ccgcccgtcc cgtcggcggg cccgggcttt cccgcgtggg gcgtccggcc ggcccgaacg
    24961 cccctcggcc ggctccacgg cacgaacaca cgaacccgag aggacctctc gatgaaggct
    25021 ctggtgctcg caggcggctc cggtacccgc ctgcggccgt tcagttactc gatgcccaaa
    25081 cagctcatcc ccatcgcgaa cacccccgtc ctggtgcacg tgctgcgggg tgtccgggac
    25141 ctgggggtga ccgaggccgg cgtcgtcgtc ggcgaccgcg ggcccgagat cgaggccgtg
    25201 ctcggcgacg gctcccggtt cgggctgcgc atcacctaca tcccccagga cgcgccgcgc
    25261 ggcctggccc acgcggtgtc cgtcgcccgc ggcttcctcg gcgacgacga cttcgtgatg
    25321 tacctgggcg acaacatgct gcccgacggg atcaccggca tcgccgagca gttcgccgcc
    25381 caccgcccgg ccgcccaggt cgtcgtccac aaggtgcccg acccgcgctc cttcggggtc
    25441 gccgaactcg gccccgacgg cgaggtgctg gccctggcgg agaagccggc gcacccgcgc
    25501 agcgacatgg cgctcatcgg cgtgtacttc ttcacaccgg ccatccacga ggcggtgcgg
    25561 gccatcgggc ccagcgcccg gggcgagttg gagatcaccg acgcgatcca gtggctggtc
    25621 tcctcaggcg cggacgtccg ggccggccag tacgacgggt actggaagga caccggcgag
    25681 gtcgagggcg tcctggagtg caacagccgc ctgctcgacc gcctgggacg gcgcgtcggc
    25741 ggccacgtcg acgacgccag cgtcctggtc ggccgggtcg tggtcgaggc gggggcgcgc
    25801 gtgctgcggt ccctggtcca gggtccggcg atcatcggcg ccggcaccgt cgtggaggac
    25861 agccacgtgg gcccgtacac ctcgatcggg cggaactgcg tggtcgctgg cagccggctg
    25921 gagagctcca tggccctgga cggggcgaag gtcaccggcg tcctcggcct gcgcgactcg
    25981 ctgatcgggc gggccgccct ggtcggcacc accggcgccg gcgcggacca ccactgcctg
    26041 gtcgtcgggg accacacccg ggtggaggtg gcggcatgag aatcctggtc accggagcgg
    26101 ccggcttcat cggctcccac ttcgtccgcg aactgctcgc cgacgcctac gccgggtggg
    26161 cgggcgccca cgtcaccgcc ctggacaagc tgacctacgc cggcaaccgg gacaacctgc
    26221 ccgccgcgca cgagcggctg gcgttcgtcc acggcgacgt ctgcgaccgc gacctgctcg
    26281 ccgaactcct gccgggccac gacgcggtgg tccacttcgc ggccgagtcc cacgtcgacc
    26341 gctccctgga gcacgccggc gccttcttcc gcacgaacgt cctgggcacc cagaccctgc
    26401 tggacgccgt gctggacagc gacgtggaac gcgtcgtgca cgtgtccacc gacgaggtgt
    26461 acggctcgat cgaggagggc tcctggaccg aggagtgccc gctggcgccc aactcgccgt
    26521 acgccgcctc gaaggccggc gcggacctgg tcgcgcgggc ctactggcgc acccacggcg
    26581 tggacctgtc cgtcacgcgc tgctccaaca actacggccc cttccagcac cccgagaagc
    26641 tcatcccgcg gttcgtcacg aacctgctgg agggccgccg ggtcccgctg tacggcgacg
    26701 ggcgcaacgt ccgcgagtgg ctgcacgtgg acgaccactg ccgcggcgtc cacctggtgc
    26761 tcaaccacgg ccagcccggc gaggtctacc acatcggcgg cggcaacgcg tacacgaacc
    26821 tcgcgctgac cgaggcgctg ctcgacctga ccggcgccgg cgaggagatg gtccgccgcg
    26881 tgccggaccg cagggggcac gacctgcggt actcgatcga cgattcgaag atccgcgagc
    26941 agctcggcta cgccccgcgg acggacttcg cgaccggtct ggccgagacg gtcgcctggt
    27001 accgggacaa cccggactgg tggaaggccg ccgcgcacgg cgagagcccc gcgcccggcg
    27061 agaaccccgc ggacggggcg cgccatgagg acggggcgcg ccatgcggtc tgacgcccgc
    27121 ccggtggccg ggctgcgcgt ggtcgtcctg ggcggtaccg gattcgtcgg ccgccacgtc
    27181 gtcgagggct tcgccgcgct cggcgcgagc gtgctgccgg tctcccgcac cggcgggcac
    27241 gccggcgcgc gggtgcgccc gccgctgcgc ctcgacctgc tcgcggcgac gcccgggcgc
    27301 atcgccggga tgctcggcga ggccggcgcc gacgtggtgg tcaacgcggc cggccaggtc
    27361 tggcggtcgg acgaggagca gatggcggcg ggcaacgccg cgctggtcga gcgcctcctc
    27421 accgcgctcg cctcgatgcc cggcgatccg ccgcggctcg tccagctcgg caccgtccac
    27481 gagtacgggg ccggcgcgcc ggacgccggc accggtgagg accacccgcc cgccccggtc
    27541 accgcctacg ggcggaccaa gctgctgggc acccgggccg tgctgggcgc cgtacaggag
    27601 cggggcgtgg acgcggtggt gctccggctc gccaacgtga tcgggtccgg ggtgccggag
    27661 ggcagcctct tcggccgggt cgcggcccac ctcggcgcgg ccgcgcacgc cgtccgacgc
    27721 ggcgggcggg ccgccgagtt gcggctcccg ccgctgcgcg ccgcccgcga cctggtggac
    27781 gcgcgcgacg ccgccgcggc ggtgctggcc gcggccacgg cgccgggggc ggccgtcacg
    27841 ggccgggtgg tcaacgtggg ccgcggcgag gcggtcccga tgcgcgggct gatcgaccgg
    27901 atggtcgcgc tgagcggcat ccgggtcccg gtcgtcgagg aaccgctgtc cccgtcctcg
    27961 cgcaccgacg tcgcctggca gcggctggag atcgcgcgcg ccgggcggtt gctgggctgg
    28021 cgcccgcgcc gggacctcga cgactcgctg cgcgacctgc tcgcgcccgt actgccgccg
    28081 gaccggccac cgctcggcgg cacggtccac gcaccgcacc cggaggagga gtcaccgtga
    28141 gcgaccgcaa ggaacggata ctcgaggacg tccgccggca ccaccaggag gtctccccgg
    28201 aacgggagtt cgtgcccggc acgacggaga tctggccgtc cggcgcggtg ctggacgaga
    28261 cggaccgcgc ggccctggtg gaggccgcgc tggacatgcg catcgcggcc gggcgcagcg
    28321 cccgctcgtt cgagtcctcc ttcgcccggc ggatggggcg ccgcaaggcc cacctgacca
    28381 actccggttc gtcggcgaac ctgctggccg tgtcggcgct gacctcgcac gtcctggggg
    28441 accgccggct gcggccgggc gacgaggtga tcaccgtcgc ggcgggcttc ccgaccaccg
    28501 tcaacccgat cctgcagaac ggcctcgtgc cggtcttcgt ggacgtggac ctcgccacct
    28561 gcaacacgac ggccgaccgg gtggccgccg cgatcgggcc gaggacgcgg gcgatcatcg
    28621 tcgcgcacgc gctgggcaac ccgttccccg tcaccgagat cgcccgactc gccgaggaac
    28681 acggcctgtt cctgatcgag gacaactgcg acgcggtcgg ctcgcggtac gacgggaagc
    28741 tgaccggctc cttcggcgcc atggccaccg tcagcttcta cccggcgcac cacctcacga
    28801 tgggcgaggg cggctgcgtg ctgacctcgg acctgggcct ggcccggatc gtggagtcgc
    28861 tgcgggactg gggccgggac tgttggtgcg agcccggcga gaacgacaag tgcctcaagc
    28921 gcttctcgta ccagatgggc accctgcctg ccgggtacga ccacaagtac atcttctccc
    28981 acgtcggcta caacctgaag gcgaccgaca tccaggcggc gctgggcctg agccagttgg
    29041 ccaggctcga cgacttcatc gcggcccgga agcgcaactg gcggcggctg cgggacagtc
    29101 tggacggggt gcccggcctg ctgctgcccg aggccacccc gcgctccgac ccgagctggt
    29161 tcggcttcgt gctcaccgtc gatccccggg cggcgtacag ccgcgccgag ctggtggcct
    29221 tcctcgaagc ccgcaagatc ggcacccgcc ggctgttcgc cggcaacctc acccggcacc
    29281 cggcctacat cgggcggccg ttccgggtgg tgggcgggct ggagaacagc gacgtcatcg
    29341 ccgaccacac cttctggatc ggggtctacc cggcgctcac cgacgagatg ttggactacg
    29401 tctccgcctc gatcaaggag ttcgcggcct cgcacggctg agccggccgg ccgtccggag
    29461 cagccgcccg caccgaccgt cccgagcggg cagccgcccg cgtcccaccg cccccgcgcc
    29521 gccgcgtccg accgccggga cccggcgcac cgaacccagg gagacccctg atgctttccc
    29581 cgcccctccg tcccccgctc caggcgcgtg tggacgcgcg cctgcgctcc cgcatcgcgc
    29641 tgtccgccgc ggccgaggaa ggcgtccagt tgcgcaccgg ggacttcgcc gcctggctgg
    29701 ccgagcgcgg ccgggccacc gacttccgcg tggagcgcat cccgttcgcg gagctggacg
    29761 gctggtcgtt cgacgagcgc accggcaacc tcggccaccg cagcggccgc ttcttcaccg
    29821 tcgagggact gcacgtcacg gaggaggccg gccccttcgg ggacggcccc tacgccgact
    29881 ggtaccagcc catcatcaag cagcccgagg tcggcatcct cggcatcctc gtcaaggagt
    29941 tcgacggggt gccgcacttc ctgatgcagg ccaagatgga gccgggcaac ccgaacctgc
    30001 tccagctctc ccccaccgtc caggccaccc gcagcaacta caccaaggcc cacaagggcg
    30061 cggacgtgaa gtacatcgag tacttcgccg gtccgcgccg cggccgcgtc atcgccgacg
    30121 tgctccagtc cgagcacggc tcgtggttct accggaagtc caaccggaac atgatcgtcg
    30181 aggccaccgg cgacgtgccg ctgctcgacg acttctgctg gctcaccctc ggccagatca
    30241 gcgcgctgct gcaccgggac aacgtggtga acatggactc gcgcaccgtg ctgtcctgcc
    30301 tgccgcaccc ggacaccgcg gcgcgcgcgc tgctcagcga catcgagctg tcctcctgga
    30361 tcaccgggga gcgcgcccgg cacgacgtgc gcaccgagcg ggtcccgctg gcctccgtcc
    30421 cccggtggaa gcgcggcgag agcaccatcg agcacgagga cggccgctac ttccgggtcg
    30481 tggcggtgtc ggtgcgggcg ggcaaccgcg aggtcaccgg atggacccag ccgctcttcg
    30541 aaccggtggg ccagggcgtc accgccttcc tgtcccgcgc gttcgacggc gtgcgccacg
    30601 tcctggtggc cgcccgcgtc gagggcggct tcctcgacac catcgagctg ggccccacgg
    30661 tgcagtgcac cccggacaac tacgcccacc tcgccccgcc ggaccggccg ctgttcctcg
    30721 acacggtgct gcgcgcgccc gcggaccgca tccgctacga ggcgatccac tccgaggagg
    30781 gcgggcgctt cctcaacgcg gagagccgct acctgatcgt ggacgcggac gagtccgacg
    30841 cgccgcagga cccgccgccc ggcttcgcct gggtcacccc ggcgcagctc acctcgctgg
    30901 tccgccacgg ccactacctc aacgtccagg gccgcagcct gctggcgcgc ctcaacgcgg
    30961 ccgagccggc cggccggtga gcacaccggt gcgcatcggg gtgctcggct gcgcggacat
    31021 cgcggtgcgc cggatgctcc ccggtttcgc ggccggtccg gacaccgagg tcgtcgccgt
    31081 cgccagccgg cggctggcgg cggcggagcg ggtcgcggag cgcttcggcg gccgcgcggt
    31141 gcgcggctac gccgggctgc tggaactcga cgaggtggac gcggtctacg tgccgctgcc
    31201 cgcctcgctg cacgaccggt gggccgaggc cgcgctcgac gccggcaagc acgtgctcgc
    31261 ggagaagccc ctcaccgcga gcgccgcccg caccgggcgg ctgctggacc tggcccggga
    31321 ccgcgggctg gcgctgatgg agaacgtcct gttcgtccac caccggcggc acgcggcggt
    31381 acggcgcctg gtggccgacg gcgcgatcgg cgaactgcgt tcgctgcacg ccgcgttcag
    31441 cattcccgcg ctgccggaca ccgacatccg ctaccggccc gaactgggcg gcggcgcgct
    31501 ggccgacgtc ggcgtctacc cgctgcgcgc ggccctgcac tttctcggcc ccgggctgga
    31561 ggtcgccggg gcggtgctcg cccgggagga cggccgcgag gtcgagacgt ccggcgccgc
    31621 cctcctgcgc acccgcgagg gcccgaccgc gcaggtcgcc ttcggcatcg ggcaggcgta
    31681 cctgtcccgg tacgaactgc ggggcagcac cgggcggatc acggtggacc gcgcgttcac
    31741 cccgcccgcc gacctcgtcc cggtgatcgg gctgcaccgg ggcggacagc gggaggagat
    31801 ccggctcgcc ccgcacgacc aggtggccgc cgcaatcgcc gccttcgccg ccgcggtgcg
    31861 cgccggctcc gccccggccg aggagacgct gcgccaggcc cggctgctgg acgacgtccg
    31921 cgcgcacgcc gcgtga
//
