LOCUS       BGC0002398             10393 bp    DNA     linear   PLN 23-MAR-2023
DEFINITION  Arabidopsis thaliana chromosome 3.
ACCESSION   BGC0002398
VERSION     BGC0002398
KEYWORDS    .
SOURCE      Arabidopsis thaliana (thale cress)
  ORGANISM  Arabidopsis thaliana
            Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
            Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae;
            Pentapetalae; rosids; malvids; Brassicales; Brassicaceae;
            Camelineae; Arabidopsis.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 17:33:46
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10393
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10393
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="True"
                     /core_location="[143:2630]"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      144..2630
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     cand_cluster    1..10393
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..10393
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0002398"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..10393
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="terpene"
                     /region_number="1"
                     /rules="(Terpene_synth or Terpene_synth_C or phytoene_synt
                     or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps
                     or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /subregion_numbers="1"
                     /tool="antismash"
     mRNA            complement(join(1..437,518..766,846..984,1253..1474,
                     1549..1924,2014..2706))
                     /db_xref="Araport:AT3G29410"
                     /db_xref="TAIR:AT3G29410"
                     /locus_tag="AT3G29410"
                     /product="Terpenoid cyclases/Protein prenyltransferases
                     superfamily protein"
     gene            complement(1..2768)
                     /db_xref="Araport:AT3G29410"
                     /db_xref="TAIR:AT3G29410"
                     /locus_tag="AT3G29410"
     mRNA            complement(join(1..437,518..766,846..984,1253..1474,
                     1549..1924,2014..2287,2373..2768))
                     /db_xref="TAIR:AT3G29410"
                     /db_xref="Araport:AT3G29410"
                     /inference="Similar to RNA sequence,
                     EST:INSD:DR238837.1,INSD:AI998171.1,INSD:DR219999.1,
                     INSD:BX840498.1,INSD:BP575666.1,INSD:BP565818.1,
                     INSD:DR238835.1,INSD:BP799939.1,INSD:DR375029.1,
                     INSD:AU235877.1,INSD:BP577306.1,INSD:BP570235.1,
                     INSD:DR238836.1,INSD:AU226649.1"
                     /inference="Similar to RNA sequence,
                     mRNA:INSD:AK227963.1,INSD:BX822709.1"
                     /locus_tag="AT3G29410"
                     /product="Terpenoid cyclases/Protein prenyltransferases
                     superfamily protein"
     CDS             complement(join(144..437,518..766,846..984,1253..1474,
                     1549..1924,2014..2230))
                     /codon_start=1
                     /db_xref="Araport:AT3G29410"
                     /db_xref="TAIR:AT3G29410"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Terpene_synth_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Terpene_synth"
                     /gene_kind="biosynthetic"
                     /locus_tag="AT3G29410_rename1"
                     /product="Terpenoid cyclases/Protein prenyltransferases
                     superfamily protein"
                     /protein_id="ANM63395.1"
                     /sec_met_domain="Terpene_synth (E-value: 1.1e-49, bitscore:
                     156.2, seeds: 149, tool: rule-based-clusters)"
                     /sec_met_domain="Terpene_synth_C (E-value: 4.1e-101,
                     bitscore: 325.6, seeds: 87, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLMSPHSSDKERIRLIHLLISLGIAYYYENEIEEILHKAYGKLAC
                     LISDEDDLETIAIMFEVFRLYGHKMPCDVFERFKSEDGKFKESLVGDVRGLLQLYEAAH
                     LGAPSEDIMDEALSFARYHLEPLAGTETSSNLFKHVENVLYRARYHSIEILVARQYISF
                     YDQEEDQDETLLRFSKLNFNFCQMHYVKELKIVTRWWKELGIASKLPYSIRERNVETYL
                     GGLGVLFEPRYSLARIFLAKLTLIMTVVDDTCDAYATLPEVQSLHDAFHRWDLRAMEEL
                     PRYMRIIYQSVFETVEDIDREMIARGKHGRLQLTIDEIKSLMIWYLGIAKWARSDQVPS
                     FEDYMEIGTPSSALDDFASYGFIAMDDCDQKQLKEWFYSKPKIFHALNALFRIRNDIVT
                     FEQEMSRGEVANGVNCYMKQHGVTKEAAVEELRKMERESYKIMIEEFMTSKAMPRQILV
                     RPVNIARVMDLFYKEADGFGHPDQKLLQLIASLFLHPIPL"
     CDS             complement(join(144..437,518..766,846..984,1253..1474,
                     1549..1924,2014..2287,2373..2630))
                     /codon_start=1
                     /db_xref="TAIR:AT3G29410"
                     /db_xref="Araport:AT3G29410"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Terpene_synth_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Terpene_synth"
                     /gene_kind="biosynthetic"
                     /inference="Similar to RNA sequence,
                     EST:INSD:DR238837.1,INSD:AI998171.1,INSD:DR219999.1,
                     INSD:BX840498.1,INSD:BP575666.1,INSD:BP565818.1,
                     INSD:DR238835.1,INSD:BP799939.1,INSD:DR375029.1,
                     INSD:AU235877.1,INSD:BP577306.1,INSD:BP570235.1,
                     INSD:DR238836.1,INSD:AU226649.1"
                     /inference="Similar to RNA sequence,
                     mRNA:INSD:AK227963.1,INSD:BX822709.1"
                     /locus_tag="AT3G29410"
                     /note="Terpenoid cyclases/Protein prenyltransferases
                     superfamily protein; FUNCTIONS IN: lyase activity,
                     magnesium ion binding; INVOLVED IN: metabolic process;
                     EXPRESSED IN: embryo, root, flower, seed; EXPRESSED DURING:
                     F mature embryo stage, petal differentiation and expansion
                     stage, E expanded cotyledon stage, D bilateral stage;
                     CONTAINS InterPro DOMAIN/s: Terpene synthase, metal-binding
                     domain (InterPro:IPR005630), Terpenoid synthase
                     (InterPro:IPR008949), Terpenoid cylases/protein
                     prenyltransferase alpha-alpha toroid (InterPro:IPR008930),
                     Terpene synthase-like (InterPro:IPR001906); BEST
                     Arabidopsis thaliana protein match is: Terpenoid
                     cyclases/Protein prenyltransferases superfamily protein
                     (TAIR:AT3G14490.1); Has 1701 Blast hits to 1673 proteins in
                     176 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi -
                     0; Plants - 1697; Viruses - 0; Other Eukaryotes - 4
                     (source: NCBI BLink)."
                     /product="Terpenoid cyclases/Protein prenyltransferases
                     superfamily protein"
                     /protein_id="AEE77582.1"
                     /sec_met_domain="Terpene_synth (E-value: 7.2e-55, bitscore:
                     173.1, seeds: 149, tool: rule-based-clusters)"
                     /sec_met_domain="Terpene_synth_C (E-value: 6.6e-101,
                     bitscore: 324.9, seeds: 87, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEASKCFGPRTLPIIHNVPLCLKTNFSLFPCRLLQSQSLSSKKST
                     KHYLFRVKAETSGDLESTRPLTYFSPSYWGDHFLSVSIDDSEFEALEKEIETVFKPKVR
                     DMLMSPHSSDKERIRLIHLLISLGIAYYYENEIEEILHKAYGKLACLISDEDDLETIAI
                     MFEVFRLYGHKMPCDVFERFKSEDGKFKESLVGDVRGLLQLYEAAHLGAPSEDIMDEAL
                     SFARYHLEPLAGTETSSNLFKHVENVLYRARYHSIEILVARQYISFYDQEEDQDETLLR
                     FSKLNFNFCQMHYVKELKIVTRWWKELGIASKLPYSIRERNVETYLGGLGVLFEPRYSL
                     ARIFLAKLTLIMTVVDDTCDAYATLPEVQSLHDAFHRWDLRAMEELPRYMRIIYQSVFE
                     TVEDIDREMIARGKHGRLQLTIDEIKSLMIWYLGIAKWARSDQVPSFEDYMEIGTPSSA
                     LDDFASYGFIAMDDCDQKQLKEWFYSKPKIFHALNALFRIRNDIVTFEQEMSRGEVANG
                     VNCYMKQHGVTKEAAVEELRKMERESYKIMIEEFMTSKAMPRQILVRPVNIARVMDLFY
                     KEADGFGHPDQKLLQLIASLFLHPIPL"
     gene            4577..5648
                     /db_xref="Araport:AT3G29420"
                     /db_xref="TAIR:AT3G29420"
                     /gene_synonym="MUO10.7"
                     /locus_tag="AT3G29420"
                     /pseudo=""
     misc_RNA        join(4577..4596,5510..5648)
                     /db_xref="Araport:AT3G29420"
                     /db_xref="TAIR:AT3G29420"
                     /gene_synonym="MUO10.7"
                     /locus_tag="AT3G29420"
                     /note="pseudogene of geranylgeranyl pyrophosphate synthase
                     3; AT3G29420.1"
                     /pseudo=""
     gene            8836..10393
                     /db_xref="Araport:AT3G29430"
                     /db_xref="TAIR:AT3G29430"
                     /gene_synonym="MUO10.10"
                     /locus_tag="AT3G29430"
     mRNA            join(8836..9479,9584..10393)
                     /db_xref="TAIR:AT3G29430"
                     /db_xref="Araport:AT3G29430"
                     /gene_synonym="MUO10.10"
                     /inference="Similar to RNA sequence,
                     EST:INSD:DR360822.1,INSD:EG505127.1,INSD:EG506636.1,
                     INSD:DR360821.1,INSD:DR379053.1,INSD:DR273471.1,
                     INSD:EG505122.1,INSD:T41558.1,INSD:AA585960.1,
                     INSD:EG506632.1"
                     /inference="Similar to RNA sequence, mRNA:INSD:DQ056612.1"
                     /locus_tag="AT3G29430"
                     /product="Terpenoid synthases superfamily protein"
     CDS             join(8997..9479,9584..10174)
                     /codon_start=1
                     /db_xref="TAIR:AT3G29430"
                     /db_xref="Araport:AT3G29430"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182:Polyprenyl synthetase (Score: 230.4; E-value:
                     4.2e-70)"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="MUO10.10"
                     /inference="Similar to RNA sequence,
                     EST:INSD:DR360822.1,INSD:EG505127.1,INSD:EG506636.1,
                     INSD:DR360821.1,INSD:DR379053.1,INSD:DR273471.1,
                     INSD:EG505122.1,INSD:T41558.1,INSD:AA585960.1,
                     INSD:EG506632.1"
                     /inference="Similar to RNA sequence, mRNA:INSD:DQ056612.1"
                     /locus_tag="AT3G29430"
                     /note="Terpenoid synthases superfamily protein; INVOLVED
                     IN: isoprenoid biosynthetic process; EXPRESSED IN: root;
                     CONTAINS InterPro DOMAIN/s: Polyprenyl synthetase-related
                     (InterPro:IPR017446), Terpenoid synthase
                     (InterPro:IPR008949), Polyprenyl synthetase
                     (InterPro:IPR000092); BEST Arabidopsis thaliana protein
                     match is: Terpenoid synthases superfamily protein
                     (TAIR:AT3G32040.1); Has 16721 Blast hits to 16714 proteins
                     in 2936 species: Archae - 341; Bacteria - 9398; Metazoa -
                     333; Fungi - 416; Plants - 457; Viruses - 12; Other
                     Eukaryotes - 5764 (source: NCBI BLink)."
                     /product="Terpenoid synthases superfamily protein"
                     /protein_id="AEE77583.1"
                     /transl_table=11
                     /translation="MATTLSSSSLFIQFRGRRYNSLSSFNNLQKRTVLSLSCALSSQGG
                     DMIPPEGKSNDRNSAFDFKSYMIRKAESVSAALNVSVPLQEPLTIQEAVRYSLLAGGKR
                     VRPLLCIAACELVGGDEATAMSAACAVEMIHTSSLIHDDLPCMDDADLRRGKPTNHKEF
                     GEDMAVLAGDALLALAFEHMTFVSNGLVAPERMIRAVMELAKAIGTKGLVAGQVTDLCS
                     QGLNPDDVGLERLEFIHLHKTAALLEAAAVLGAIMGGGTEEEIEKLRKYARCIGLLFQV
                     VDDILDVTESTKELGKTAGKDVMAGKLTYPRLIGLERSREVAEKLRREAAEQLLGFDSD
                     KAAPLVALASYIACRHN"
ORIGIN
        1 tattaatatc aaatatatta aaagttataa cggtttggta aaataaatta aagaaaattc
       61 aaattcaaag taaacatata caaaacactt attcaaagtc acatacatat ataaaaactc
      121 cttatataac tttttataaa tgttcaaaga ggtattggat ggaggaacaa agacgcaata
      181 agttgtaaga gcttttgatc aggatgccca aatccatcgg cttctttgta aaacaaatcc
      241 attacacgcg caatgttgac gggtcgcacc agaatctgtc gtggcatagc tttggacgtc
      301 atgaactcct caatcattat cttataactc tctctttcca tcttcctcag ttcttcaacc
      361 gctgcttctt tggtgacacc atgttgcttc atgtaacagt tgacaccatt tgccacctct
      421 cctctgctca tctcttgctg tttattgtat tacttacatt agagatcttc caatagtacc
      481 taggaaagaa gataataatt aaaacttgtg tacgtacctc gaacgtgaca atgtcatttc
      541 tgatacgaaa cagagcattc aaggcatgaa agattttagg tttggagtaa aaccattcct
      601 tcaattgctt ctgatcacaa tcgtccattg ctataaagcc gtaggatgca aagtcatcca
      661 atgcagacga gggtgtccca atctccatgt aatcctcaaa gcttggcact tgatctgagc
      721 gtgcccattt tgctatccca agataccata tcatcagact cttgatctgc aaggatcgtt
      781 gtcctttgtt aattgacttt taattggttt ctactcttgc tactacttga gttcgatcaa
      841 cttacctcat ctatggttag ttgcaaccga ccatgttttc ctcgagctat catttctcga
      901 tcaatatctt ccacagtctc gaacacactt tggtagatga ttctcatata cctcggtagt
      961 tcttccatgg cacgcagatc ccatctggac atttgtttct ggttaaatac attgatatat
     1021 gataacatca taaatgcatg agatcttggc atgtaggagg ctagtgaaac aatttttgtg
     1081 gccctaagtt tttttttttt ttttttctaa aattcattag ccaatttagt ccaaattttc
     1141 ttaagcttaa aaaacaacat gatttttttc tttaaagctt tggcccaaca atttttaggg
     1201 tcgaccctgc atgtatgcag aatggttgta tataagacct ctacatacat acctatgaaa
     1261 agcatcatga agactctgaa cttcaggaag agtggcatat gcatcacatg tatcatccac
     1321 aacagtcatg atcagtgtta gtttagctaa gaaaattctt gcaagtgaat atcgcggctc
     1381 gaaaagcact cccaagcccc caagataagt ctccacattt cgctccctta tggagtacgg
     1441 tagcttagat gcgataccta gctccttcca ccatctagaa ccataaatta ggttacataa
     1501 aaaagaatat tgacgacgaa agatgttata tatatacaat atacttacct agtgacaatt
     1561 ttgagctctt tgacgtaatg catctggcaa aaattgaaat tgagctttga aaacctaagg
     1621 agcgtctcat cttggtcttc ttcttgatca tagaaagaga tgtactgtcg tgctactagt
     1681 atctctatgc tatgatatcg agctctatac aaaacgtttt ctacatgctt aaaaagatta
     1741 gagcttgttt cggtgcctgc caacggttcc aagtgatacc gcgcaaaact taaggcttca
     1801 tccattatat cttcagatgg tgctcctaga tgcgcggctt cgtacagctg tagcagccct
     1861 ctaacatccc caactaaact ttccttaaac ttcccatctt cgcttttgaa tctctcgaac
     1921 acatctaccc caaaccatta tatgctttgt tatatatatt tgtgaaacaa aaaaactgat
     1981 ctaattaact ggtttaaata attgtcaata taccgcaagg catcttgtgt ccatatagtc
     2041 tgaaaacctc aaacatgatt gctattgttt ccaaatcatc ctcgtccgaa attaagcagg
     2101 ccaacttccc gtaagccttg tgtaaaatct cctcgatttc attctcatag taataagcga
     2161 taccgaggct gataagcaaa tggatgagac gaatcctctc cttgtcgctg ctgtgaggag
     2221 acatgagcat gtctctcact ttaggcttga acaccgtttc aatttctttc tcaagtgcct
     2281 caaattccta caaatatgca attcaaaaaa acaaatcatg tactctaaca agacatatcc
     2341 actaaaacac atcggaccag gtgtgtactt acggagtcat cgatggaaac agagaggaag
     2401 tgatctcccc aataagatgg agaaaagtac gtcaatggac gagtactctc aagatcgcca
     2461 ctagtctcag ccttaacacg gaacaagtag tgttttgtgg atttcttgga ggaaagagat
     2521 tggctttgaa gcaaacggca aggaaagaga gagaagttgg tcttcagaca gagagggacg
     2581 ttgtgaatga tagggagagt tcttggacca aaacattttg atgcttccat ttttcagaca
     2641 ctctcgttac aagagagaca cgagatcaaa gtctttactt ggcccttgtc ttaggatgta
     2701 tgtgttactt cactgcccca tcctactctg ttttaaatag atcatggata tggtggagaa
     2761 actgtaactt cttgactact ttggtgacga caattattat tattattatt attatttttg
     2821 atagctggtg acgacaatta ttgttattta tttttattag aaaggacact tattgttatg
     2881 gcacttatta gtgttgaata attcgatttt tttaattatt tatatatata tatatatata
     2941 tatatatatt ttgtaggctt tttggccaaa aatcactata ctatttacta aataacatac
     3001 aagccttaca aattttatct taaccaaata ttttatttct aagaacttat aattcgttag
     3061 tttgcattaa atatttgact taactatttc ctctattaca tatatagtcg ctacaaaatc
     3121 tatctaaaaa gataattgtt taaatttata tcacttttat attaacaaat cttatcttta
     3181 ttgaactaca ttcaattaat tcctaatttc ttaaaatctc cctatctaca ttaaatataa
     3241 acatataaat tttctttcac ttttatttgt tcttatattt aatttatttg attgtatata
     3301 aaatacatat aattaataaa acattagatt ttttctatat ataatgtaac tcaaaatttt
     3361 aaaaacagtc atatattact caatcaatga aaaaaagtgt caaatgtccc acattgctta
     3421 agaaattgag caatagttca gagtcttatt attaaagaat aaaactgatt ttaaatatga
     3481 atgagccgaa agttttattt atcaagcatc caaaattaaa agtgttatct agtttatttt
     3541 gattctatat tttaaataaa tttgtcaagc atccaaaata aatttatttt ttctaaaaaa
     3601 tcaattagaa ataaataaaa gaagtattaa ttaaagacat gcataactcg aacatggggg
     3661 ttggttgcct atctactttc cgtttctgag gcattaaaat aaatttaatt tagtgtactt
     3721 caatgtaaat tgaatataat taattagact atacttgatc catcggttaa tttattttat
     3781 tctgtaatgt cccgtctatt tttctaggaa tcgtacaagt acaataatat atatatatat
     3841 atatatatag tacaagtaca gtaatatata tatatatata cacatagtac aagtacaata
     3901 atatatatat atagtacaag tacagtaaat aaatgtgaaa atttgtgata attattggat
     3961 tagttttgtc attatactaa catttgggtg ttatattcct aagaccatat tcaatggtat
     4021 gagtggttga gggaatctta ccaatttttt aatttttaaa ttttgacaat ttgaaagttt
     4081 agcaattcta ttggcctctt aacaattatc ttgttcaatg gtaaggtcct taagaaataa
     4141 aatttggtgt ttggtgtttt gaagttttga atagaaagat aaaaaagaga caagtgaagt
     4201 ttggtattag agtcttgata aacacatttt gaataacagg gattcatgaa aaaaaaaaaa
     4261 tatacaagag gttttgtatt aacacagatt catggcaata cataacaata atatgacaaa
     4321 gtatacaaac tgtgtgacga atctccatgt tgtaatcacc gccttgtcct aattccataa
     4381 acttgatctc agtgttccct ggattccaca gtccacttga accatttcat caaaaatgac
     4441 acgcgatgtt aagctgtgtg agacaataac aaagtttagc tcatgagacg ggttgatgtg
     4501 gagtctgttc atgtcgtcga tgtcttcgta gagacttgat aaaatctgta caacaacact
     4561 caaaaaagac caaagcatga gtcttaatac cttcttgttc attcacacag agattgatgg
     4621 aagaaaagca caacaaagag aagataaaac aacaacgatg aaactgacta gctagattct
     4681 tgctaagcct gcattattct gacacttcaa atttcaatag agattgatga aaaaaaaaat
     4741 cagtgctacc ttgcttctca aaaaaaaaaa aaaaaaaata tttattgagt tttaattttt
     4801 tttttggctt aatatttaag gattttggct ttagaacttt ttttaagtat cattaatagc
     4861 accctcaata gagggttttt agatagtttt tatgtataga aaagataaaa atattagaaa
     4921 atgaagagaa aataagaaaa aactcgtata taagagactt gaaattttat ataagagcca
     4981 aatgagtcac atgtcttcgt taaattgatt cattttttaa aaaaagattt aaaatttaat
     5041 tatttcagta aattataata aaataataat attttggtat taaagagaaa acatttagaa
     5101 tcctccattg atgatgcccg ttggaaagag ctattgccac ttgctacaac agatcacata
     5161 acaatcatag aacataataa agattttttc gcatttcatt ttattattat ttattagtaa
     5221 gaaatcgagt cgtaacaata cgcacataag tgaaaatttt tgaaaaattt gtcaattctt
     5281 tttatattgt ttttaactaa ttaagatgtt ttttttgccg taattaattg atatgttaaa
     5341 atgtatatat agaattagta tttcaaattt atgtcttata tacaaatgtc tcaactttca
     5401 aattttacat ttttcgtaat atataatgag atgtaaacga taaaacctac atttcatttc
     5461 agttgtatta catacatata caatacttaa ggttttagta aatattgagg ttgattggtt
     5521 tggaaagatg gaaggaattt gcagagaaat tgaacaaaga agtagacaaa caacttctag
     5581 ggtttgatcc gaataatgcg gcacctctgg tggctgttgc tagttacatt gctggaagac
     5641 acaattgagc tcttgcaagt tacattgcta ggttggttta ataagactct aggataaaag
     5701 ttttatccaa agttccccac tttcaactgt tttatccaaa aatctataaa ttttcaatga
     5761 acataactac ccgagatgta ccggatcaat ctctaggatg tcattttgaa ggaaaatggg
     5821 atttagaaat aaattttcaa cccgcgatct aacaaaaata taaacccgtg gtgtaccatg
     5881 ggtcaatgaa ttacccaaac tttacataga ttaaaattat gtttcaaaaa tatattattc
     5941 atatataaat attaattttt ataaaaatat ctataacttt taaatgaaca tatccaccca
     6001 cggtacaccg cgaatcaata tctaattagc aacatcattt gttttaagac attaaatact
     6061 ttgaaaataa agtatagcat ttaaagcttc taactttttg ttgaattact catgttttat
     6121 tttatcaaat tgaagtactc tctttggtaa agaattcctc tacttttatt ggagtcattc
     6181 tgtatttcag aaacattatt tgttgttaaa ctggttttta aattactcag ctttagtatc
     6241 tattatattt atgtatttca aaagcttatt ttctgcatta tgtttttact ttttagttaa
     6301 aaaccaaaaa taataaataa tactaattaa ataaaatata gctaatcccc tgttaatctc
     6361 gaaaatatgt aggatgataa tgtaagataa atcataaacg aatctttttt ttcaataaga
     6421 gaagaatctt acctgccatt aaagatttaa attatataaa taagattatg ggacaagaaa
     6481 aatgacatac gaataaaatc actaactttc tttatacata ataacagcca atggcggagg
     6541 cacaatatta gtaaggggtc agatgaccga cccccataaa tctttgaatt tttgcttaca
     6601 agcttatgct ctatttgatt attgtggtaa attgattgct ttctaataaa ttgacctcat
     6661 gtccagtggt catatctttt ctttgcacct atggaaacga tattatattt attcaactat
     6721 atcttttgca attatgtttt aagaaataat tactgaaact atcacaaaat atgtaaaatg
     6781 gaattatata tatactgtat ttgatgaata aagaacaata atgattatct tttattttat
     6841 ttatttttaa atacaatgaa ttttaaattt ttaaagttag atttttttag aaatgaaata
     6901 ttatatttaa atatttaatt aaaactaaaa ataaaatatg acccctaaac aattttttct
     6961 agctctacca ctgataacag ctagacattg catgtctatc aacaatctcc ccctgtatta
     7021 tattcttaat cagaacctct tggggatcac aaggaaacga aatgaagatt accaaaaaga
     7081 aaaagaaaaa aaaagtagaa gaaaagaaat ggatgatatc aaaggtccaa aaccaccgta
     7141 gaggagtact ctttttgttc cttattaatt gtgtttttag agaatttttt tttttcaaaa
     7201 agattgattt ttatatttct atgccttatt tattagttat tattgatgaa ttttaaactg
     7261 aaaaacaaat aattgaataa cattgatgta gaattacaca aaaatgtaaa tcacaaaaca
     7321 atacatttgt aaatcaattt taatataatt tcttaataaa tttgtttttt ctaaaaaaat
     7381 aattaaaata aataaaggaa atatgaatta aagacatgca taattcgaac atgggggttg
     7441 gttgcctatc tactctccgt ttccgaggca ttaaaataaa tttaatttag tgtacttaat
     7501 gtaaattgaa tataattaat tagtctatac ttatccatcg gttaatttat tttattctgt
     7561 aatgaccctt ctattttttt agtaatccta caagtacaat aatatatata tatatatata
     7621 tatatagtac aagtacagta atatatatat atatatatat atatatatag tacaagtaca
     7681 gtaatatata tatatatata tatatatagt acaagtacag taaataaatg tgaaaatttg
     7741 tgataattat tggattagtt ttgtcattat actaacattt gggtattata ttcctaagac
     7801 catattcaat ggtatgagtg cttgagagaa tcttacctat tttttaattt taaattttga
     7861 caatttgaaa gtttagcaat tctattggcc tcttaacaat tatcttgttc aatggtaagg
     7921 tccttaagaa ataaaatttg gtgtttggtg ttttgaagtt ttgaatagaa agatagaaaa
     7981 gagacaagtg aagtttggca ttagagtctt gataaacaca ttttgaataa caaggattca
     8041 tgaaaaaaaa aaaaaataca agaggttttg tattaacaaa gattcatgac aatacataac
     8101 aataatatga caaagtatac aaactgtgtg atgaatcgcc atgttgtaat caccgccttg
     8161 tcctaattcc ataaacttga tctcagtgtt ccctagattc cacagtccac ttgaaccatt
     8221 tcatcaaaaa tgacacgcga tgttaagctg tgtgagacaa tcacaaagtt tagctcatga
     8281 gacgggttga tgtggagtct gttcatgtcg tcgatgtctc tgtagagact tgagaaaacc
     8341 tgtacaacaa cactcaaaaa agaccaactt ctagggtttg atctgaataa tgcggcatct
     8401 gtggtggctg ttgctagtta cattgctgga agacacaatt gagctcttgc tagttacatt
     8461 gctaggttgg tttaataaga atctaggata aaagttttat ccaaagttcc ccactttcaa
     8521 ctgttttggc tgcattgctc ttaggacatc agaattgtga agatgagcat gacgtttgac
     8581 ttgttagttc aaaactcact tgatcctgac aaaaacaggt gcttcgttgg tttaataaga
     8641 tggatgctca aggaaaaaag ttttacctaa agctccccac tttcagctgc ttttgatcta
     8701 aggactgagc atgacatatg acttgttcaa tatttacata atcctgacaa tatcaggtga
     8761 accattttat acaccagctt atgttatatg atttttctat ggatccgctt gttagaatat
     8821 gtacataaaa tgtgacttat tcgaccaaac ccataattga aaattcatat aattttgttg
     8881 gcagattaca gttttaagac aacagtaagg acgttgacct tcattgcttc caagcattcg
     8941 aaacctatta agagctccac ttaatataat attatatcgg agaaggtgga tcggccatgg
     9001 ctactactct cagctcatcc tctctcttca tccaattcag aggacggaga tacaactccc
     9061 tatcatcatt caacaatctc caaaagcgca ccgttttgtc gctttcttgt gctctatcct
     9121 cacaaggtgg agacatgatt ccaccagagg gaaaaagcaa tgatcgcaac tctgcctttg
     9181 acttcaagtc gtatatgatc cgtaaagccg aatccgtaag tgcggctctc aacgtttcgg
     9241 tacctctcca agaaccactc acgatacaag aggcggtgcg gtactcatta ctagcgggcg
     9301 gaaaacgtgt gaggcctctc ctctgcattg ctgcttgtga gctcgtgggt ggcgacgagg
     9361 ctactgccat gtcagccgct tgtgcagtcg agatgatcca cacgagctcg ctaatccatg
     9421 acgacctccc gtgcatggac gatgccgacc tccgtagagg caagcccacc aaccataaag
     9481 tatgttgtta aatcatatgg acgctaattg ctcacgagat ttgaatcatt tattgatgtt
     9541 agtatttgct cactagtgac gaactatttt ttggtcaaac aaggaatttg gagaagacat
     9601 ggcggttttg gcgggtgatg cactccttgc tttagcgttt gagcacatga cgttcgtgtc
     9661 aaatgggttg gttgcccctg agaggatgat ccgtgctgta atggagctgg caaaggccat
     9721 agggacaaaa gggctagtgg ctgggcaagt gactgactta tgtagccaag gattgaatcc
     9781 agacgacgtc ggattggagc gtctagagtt catccacctc cacaaaacgg ccgccttgtt
     9841 ggaggcagcg gcagttttag gagccataat gggaggtgga acagaggaag agatcgaaaa
     9901 gctaagaaaa tatgcgagat gtattgggct gttgtttcag gtggttgatg atattcttga
     9961 cgtaacggaa tctactaagg aattgggcaa gacagccgga aaagatgtaa tggccgggaa
    10021 gctgacgtat ccaaggctga taggcttgga gagatccagg gaagttgcgg agaaactgag
    10081 aagagaagca gcggaacagc ttctagggtt tgattccgac aaggcggcgc ctcttgtggc
    10141 tcttgctagc tacattgcct gcagacacaa ctgatatttt gcatgaactg aacatatcct
    10201 caaagcatct aatgtcctga caagtccatt cttagtttta ttattcaaaa ataaaaataa
    10261 ggtccattag attgatccat ggtcttcttt catatgaacc tttgtcttgt gatcatcact
    10321 ttgtgttctc agcttgcatt ttagtattac gtttttgaat tttaatgtca tttttcgatt
    10381 actaatatat cat
//
