BGC0002409: frankobactin A1 biosynthetic gene cluster from Frankia sp. CH37
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Location: 1,391,852 - 1,457,688 nt. (total: 65,837 nt).
This entry is originally from NCBI GenBank JADBID010000001.1.

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General information about the BGC

MIBiG accession | BGC0002409
Short description | frankobactin A1 biosynthetic gene cluster from Frankia sp. CH37
Status | Quality: questionable The quality level of this entry. Status: active The status of this entry. Completeness: unknown Whether the entry covers everything needed for the pathway producing the compound(s)

Biosynthetic class(es)

- NRPS (Type I)

Loci
JADBID010000001.1
1401852 - 1443553
via
Compounds

- frankobactin A1
- frankobactin A2
- frankobactin A3
- frankobactin B1
- frankobactin B2
- frankobactin B3
- frankobactin C1

Species Frankia sp. CH37 [taxonomy]
References

- [1] Frankobactin Metallophores Produced by Nitrogen-Fixing Frankia Actinobacteria Function in Toxic Metal Sequestration. Mohr, J et al., Journal of Natural Products (2021) DOI:10.1021/acs.jnatprod.0c01291
- [2] Frankobactin Metallophores Produced by Nitrogen-Fixing . Mohr JF et al., J Nat Prod (2021) PMID:33789052

Chemical products information
frankobactin A1 Evidence:
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NPAtlas
frankobactin A2 Evidence:
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frankobactin A3 Evidence:
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NPAtlas
frankobactin B1 Evidence:
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NPAtlas
frankobactin B2 Evidence:
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frankobactin B3 Evidence:
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NPAtlas
frankobactin C1 Evidence:
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NPAtlas
List of genes involved in compound(s) production

Identifiers | Position | Product | Functions | Evidence | Extra
--- | --- | --- | --- | --- | ---
IHE48_05520 MBE3200457.1 | 1401852 - 1403429 (+) | AMP-binding protein |  |  | copy AA seq copy Nt seq
IHE48_05525 MBE3200458.1 | 1403471 - 1404166 (-) | FadR family transcriptional regulator |  |  | copy AA seq copy Nt seq
IHE48_05530 MBE3200459.1 | 1404565 - 1406289 (+) | 2-isopropylmalate synthase |  |  | copy AA seq copy Nt seq
IHE48_05535 MBE3200460.1 | 1406388 - 1406915 (+) | hypothetical protein |  |  | copy AA seq copy Nt seq
IHE48_05540 MBE3200461.1 | 1407856 - 1410123 (+) | ATP-binding cassette domain-containing protein |  |  | copy AA seq copy Nt seq
IHE48_05545 MBE3200462.1 | 1410158 - 1411960 (-) | ABC transporter ATP-binding protein |  |  | copy AA seq copy Nt seq
IHE48_05550 MBE3200463.1 | 1411957 - 1413780 (-) | ABC transporter ATP-binding protein |  |  | copy AA seq copy Nt seq
IHE48_05555 MBE3200464.1 | 1414216 - 1415943 (+) | ABC transporter ATP-binding protein |  |  | copy AA seq copy Nt seq
IHE48_05560 MBE3200465.1 | 1415936 - 1417663 (+) | ABC transporter ATP-binding protein |  |  | copy AA seq copy Nt seq
IHE48_05565 MBE3200466.1 | 1417916 - 1437688 (+) | non-ribosomal peptide synthetase |  |  | copy AA seq copy Nt seq
IHE48_05570 MBE3200467.1 | 1438073 - 1439839 (+) | amino acid adenylation domain-containing protein |  |  | copy AA seq copy Nt seq
IHE48_05575 MBE3200468.1 | 1440116 - 1440607 (+) | aspartate 1-decarboxylase |  |  | copy AA seq copy Nt seq
IHE48_05580 MBE3200469.1 | 1440862 - 1441002 (-) | hypothetical protein |  |  | copy AA seq copy Nt seq
IHE48_05585 MBE3200470.1 | 1441057 - 1441794 (+) | SDR family oxidoreductase |  |  | copy AA seq copy Nt seq
IHE48_05590 MBE3200471.1 | 1441919 - 1442482 (-) | TetR/AcrR family transcriptional regulator |  |  | copy AA seq copy Nt seq
IHE48_05595 MBE3200472.1 | 1442558 - 1443553 (+) | alpha/beta hydrolase |  |  | copy AA seq copy Nt seq

Biosynthesis information

No biosynthesis information available for this record.

Annotation changelog

#### Entry version: 2

Date
Changes
Submitters
Reviewers
2022-10-07
Added chemical structures for compounds: frankobactin A2, frankobactin B3, frankobactin A3, frankobactin B1, frankobactin C1, frankobactin B2, frankobactin A1.

- (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

- (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

2022-10-07
Added NPAtlas links to compounds: frankobactin A2, frankobactin B3, frankobactin A3, frankobactin B1, frankobactin C1, frankobactin B2, frankobactin A1.

- (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

- (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

#### Entry version: 1

Date
Changes
Submitters
Reviewers
2022-09-15
Entry added

- (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

- (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

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